366 results about "Carnosine" patented technology

The invention belongs to the technical field of biochemical engineering, and provides a method for increasing L-carnosine yield of escherichia coli by increasing PRPP supply, and the yield and yield of L-carnosine are remarkably increased by up-regulating expression of a prs gene, increasing PRPP content in cells and promoting synthesis of L-histidine. Experiments show that the yield of the L-carnosine in different recombinant strains is increased by 55.56%-140%, and L-histidine and beta-alanine do not need to be added in the production process.

The invention relates to the technical field of enzyme engineering, in particular to an aminopeptidase mutant, a preparation method of the aminopeptidase mutant and application of the aminopeptidase mutant to preparation of L-carnosine. The aminopeptidase mutant is obtained by mutating wild type aminopeptidase and can be used for preparing the L-carnosine through reverse hydrolysis of beta-alanine methyl ester and L-histidine. The L-carnosine produced by using the aminopeptidase mutant disclosed by the invention has the following advantages: 1, the conversion rate is greater than or equal to 95%, the conversion time is short, and relatively cheap alanine methyl ester can be used as a raw material to catalytically prepare the L-carnosine; 2, the production process is simple, the reaction conditions are mild, and the green chemistry concept is met;

The invention belongs to the technical field of cosmetics, and particularly relates to essence with anti-wrinkle, repairing and skin-brightening effects as well as a preparation method and application of the essence. The essence is prepared from the following components in parts by weight: 10 to 70 parts of herba centellae extract, 0.0015 to 0.04 part of crocus sativus extract, 0.5 to 2.5 parts of spirulina maxima extract, 0.015 to 0.2 part of radix gentianae extract, 0.1 to 1.5 parts of panthenol, 0.25 to 1.5 parts of leuconostoc / radish root fermentation product filtrate, 0.1 to 1.5 parts of carnosine and 0.21 to 5.3 parts of anti-wrinkle components. According to the essence, various effective components such as the centella asiatica extract, the spirulina maxima extract and the radix gentianae extract are matched for use, a unique composite formula is formed, all the components promote one another, the anti-wrinkle, repairing and skin brightening effects of the essence can be remarkably enhanced, and therefore all-around skin care is provided for consumers, and the essence has a good market prospect. The overall quality of the skin can be effectively improved.

The invention belongs to the technical field of health-care food, and provides a composition containing ergothioneine and having sleep-aiding, whitening, anti-aging and anti-inflammatory effects and application thereof. The ergothioneine composition disclosed by the invention is prepared from ergothioneine, collagen peptide, carnosine, nicotinamide, an olive leaf extract and a chamomile extract. The components in the composition are matched for use, the synergistic effect is obvious, the whitening, anti-aging and anti-inflammatory effects are obviously improved, meanwhile, the composition also has a sleep-aiding effect, and the comprehensive performance is excellent.

The invention relates to a composition containing ceramide and collagen tripeptide and a preparation method thereof, and belongs to the technical field of health care products. The invention discloses a composition containing ceramide and collagen tripeptide. The composition is prepared from the following raw materials: collagen tripeptide, rice bran oil powder, a herba houttuyniae extract, pineapple powder, konjaku flour, a grape seed extract, olive fruit powder, carnosine, pomegranate concentrated powder and a whey fermentation product. The grape seed extract, the olive fruit powder, the carnosine and the pomegranate concentrated powder inhibit the Maillard reaction of the collagen peptide and improve the utilization rate of collagen tripeptide; ceramide rich in the rice bran oil powder is a natural skin moisturizing factor, and is matched with the pineapple powder and the konjaku flour which have a keratin metabolism effect to maintain the health of cuticles; the herba houttuyniae extract and the whey fermentation product are matched to have an excellent anti-inflammatory effect, so that the components enhance the skin barrier in multiple dimensions through collagen synthesis, cuticle maintenance, anti-inflammatory and anti-oxidation.

The invention relates to an anti-wrinkle and firming composition as well as a preparation method and application thereof. The anti-wrinkle and firming composition comprises the following components in parts by mass: 0.01-10 parts of composite polypeptide, 0.01-5 parts of recombinant collagen and 0.01-20 parts of amino acid or a derivative thereof, the composite polypeptide comprises acetyl peptide, palmitoyl peptide and carnosine. The brand-new anti-wrinkle and firming composition is developed through multi-dimensional formula design, acetyl peptide, palmitoyl peptide, carnosine and recombinant collagen are compounded, amino acid or amino acid derivatives are supplemented, the mutual synergistic effect is achieved, and the anti-wrinkle and firming purposes are achieved.

The invention relates to the technical field of microorganisms, and particularly discloses a recombinant microorganism and application thereof in fermentation production of decarboxylated carnosine. Compared with an original strain, the recombinant microorganism disclosed by the invention has the advantages that the expression of the mdtK gene is enhanced; the starting strain is escherichia coli capable of producing decarboxylated carnosine. When the recombinant microorganism is used for fermentation production, the yield of the decarboxylated carnosine can be increased, L-histidine, histamine or beta-alanine and other precursors do not need to be added in the production process, and an effective novel method is provided for industrial production of the decarboxylated carnosine.

The invention provides a preparation method and application of a camellia polypeptide composition with anti-wrinkle, repairing and brightening effects. The camellia polypeptide composition comprises a component A and a component B, wherein the component A comprises a wrapping solubilizer and polyhydric alcohol; component B: a plurality of polypeptides; the component C comprises carnosine, camellia polypeptide and water. The camellia polypeptide disclosed by the invention is prepared by the following steps: performing supercritical deoiling on camellia seeds, performing alkali extraction, acid precipitation and enzymolysis to prepare polypeptide, performing membrane filtration, taking micromolecule polypeptide as a main component, promoting synthesis of type I, type III and type V collagen, promoting cell migration and scavenging free radicals, and has the effects of resisting wrinkles, repairing and resisting oxidation; according to the invention, the problem of water solubility of palmitoyl peptide and acetyl peptide is solved, so that palmitoyl peptide and acetyl peptide can form a stable composition together with water-soluble polypeptide. The anti-wrinkle, repairing and whitening effects are achieved in multiple ways and multiple directions, the effects of improving wrinkles, repairing the skin, brightening the skin color and delaying senescence can be better achieved, and the anti-wrinkle, repairing and whitening composition can be widely applied to various types of cosmetics.

The invention discloses a preparation method of eye drops for treating glaucoma, cataract and vitreous opacification. The eye drops comprise the following components: berberine, N-acetyl carnosine and lycium barbarum polysaccharide. The specific formula comprises the following components: 0.1%-0.5% of berberine, 1%-3% of N-acetyl carnosine and 0.5%-2% of lycium barbarum polysaccharide. The invention belongs to the technical field of ophthalmic pharmaceutical preparations, and solves the problems that in the prior art, glaucoma, cataract and vitreous opacity generally need to be separately taken, the research on compound preparations is less, and the components possibly interact with one another.

The present invention relates to the fields of medicine and cosmetology, and discloses a cell active peptide composition that promotes the regeneration of multi-type collagen structural proteins, its preparation method, and its application in medicine and cosmetology. The composition uses raw materials such as tripeptide-10 citrulline, hexapeptide-9, hydrolyzed sodium hyaluronate, γ-aminobutyric acid, decarboxylated carnosine hydrochloride, acetyl tetrapeptide-3, acetyl tetrapeptide-11, palmitoyl dipeptide-7, and palmitoyl pentapeptide-4. The composition can promote the coordinated expression of skin type I, type III, type IV, type VII, type XVII collagen, fibronectin, elastin, and glycosaminoglycans; prevent collagen cross-linking, maintain triple helix structure, and inhibit collagen degradation. Applied to dermatology and cosmetology, it can accelerate the regeneration of structural proteins such as skin collagen, repair skin damage, reduce wrinkles such as crow's feet, tear groove lines, nasolabial folds, and under-eye lines, solve the skin aging problem caused by the loss of structural proteins such as collagen, and improve skin elasticity and firmness.

The embodiment of the invention discloses application of carnosine, the carnosine can be used for relieving the smell of a composition containing ergothioneine, on the basis, the invention further provides the composition containing ergothioneine and application, and the composition containing ergothioneine comprises ergothioneine, carnosine and water.

The invention discloses aminopeptidase for synthesizing L-carnosine and an application of the aminopeptidase. The amino acid sequence of the aminopeptidase is as shown in SEQ ID NO: 3 or 5. The aminopeptidase disclosed by the invention can catalyze L-histidine with high selectivity to synthesize L-carnosine in the presence of beta-alanine methyl ester, and has relatively high enzyme activity and industrial application value.

The invention relates to the field of bacteriostatic cream, and particularly discloses skin bacteriostatic cream and a preparation method thereof. The skin antibacterial cream is prepared from the following raw materials in parts by weight: 4 to 6 parts of bran coat extract, 2 to 4 parts of chlorhexidine salt, 2 to 4 parts of rutin extract, 1 to 3 parts of carnosine, 0.5 to 0.8 part of sodium hyaluronate, 0.8 to 1.2 parts of film-forming agent and 5 to 8 parts of purified water. The preparation method comprises the following steps: mixing the film-forming agent and a part of water, and uniformly stirring to obtain a film-forming agent solution; the preparation method comprises the following steps: mixing sodium hyaluronate and water, heating, stirring until the sodium hyaluronate and the water are completely dissolved, adding the cavings extract, the rutin extract, the chlorhexidine salt and the carnosine, stirring until the mixture is uniformly dispersed, heating to 75-85 DEG C, emulsifying for 25-35 minutes, homogenizing, adding a film-forming agent solution into the homogenized emulsion, and stirring, concentrating, degassing and discharging the paste in vacuum to obtain the antibacterial paste. The composition can be used for diminishing inflammation and resisting bacteria of damaged skin, and has the advantages of being high in antibacterial rate and capable of avoiding skin pigmentation.

The invention provides a tightening and repairing gynecological gel. Preparation raw materials comprise carbomer, sodium hyaluronate, an animal umbilical cord extract, madecassoside, carnosine, a polygonum cuspidatum root extract, a scutellaria baicalensis root extract, a tea leaf extract, a chamomile flower extract, elastic collagen, arginine, pentanediol, butanediol, glycerin, p-hydroxyacetophenone, capryloyl hydroximic acid and purified water. The gynecological gel can maintain balanced strains, so that the microenvironment of the vagina is kept normal; vaginal atrophy is improved, the tight state of the vagina is recovered, and vaginal dryness is relieved; damaged mucosa can be repaired, the natural defense function of women is enhanced, and gynecological infection is prevented. The gynecological gel has good biocompatibility, cell affinity and mechanical properties, and can supplement collagen to female private parts, repair damaged vaginal mucosa and promote wound healing; the vagina can be moisturized and moistened, the looseness and dryness of the vagina are improved, the micro-ecological balance of the vagina is adjusted, and the immunity of a female reproductive system is improved.

The invention discloses an active exosome stent coating based on traditional Chinese medicine enhanced secretion promotion and a preparation method and application thereof, and belongs to the technical field of biological medicine and interventional instruments. The stent coating comprises exosomes, wherein the exosomes comprise myocardial cell active exosomes and human mesenchymal stem cell active exosomes which are intensified and secreted by traditional Chinese medicines; wherein the traditional Chinese medicines comprise placenta extract, pilose antler extract, sheep myocardial peptide, sea cucumber peptide, lycium ruthenicum peptide, cnidium lactone, curculigo orchioides extract and morinda officinalis extract; the intervention concentration of each component added into cells is 2-50 [mu] g / mL; the light-cured gel matrix is prepared from methacrylated gelatin, a photoinitiator and polyether 127; tacrolimus; the final concentration of the exosome is 1 * 10 < 9 >-12 * 10 < 9 > particles / mL, and the final concentration of the tacrolimus is 5-25 mu g / mL. The coating can be coated on the surface of the poly-L-lactic acid degradable stent to prepare the degradable stent, and has obvious vascular repair promoting capability.

The invention belongs to the technical field of cosmetics, and particularly discloses an anti-wrinkle composition and application thereof in preparation of eye care products, the anti-wrinkle composition comprises carnosine, a purslane extract and a magnolia flower extract; the mass ratio of the carnosine to the herba portulacae extract to the magnolia flower extract is 1: (0.5-4.5): (0.5-4.5). The carnosine, the portulaca oleracea extract and the magnolia flower extract are combined and complement one another, so that the carnosine, the portulaca oleracea extract and the magnolia flower extract jointly exert a stronger anti-wrinkle effect. The antioxidant and moisturizing effects of carnosine can be combined with the nourishing and lubricating effects of the purslane extract, and more comprehensive protection is provided for the skin. Meanwhile, the anti-aging capability of the skin can be further enhanced by the anti-oxidation and whitening effects of the magnolia flower extract, so that the skin is young and healthy. Due to the synergistic effect, the formation of wrinkles can be reduced, the overall condition of the skin can be improved, and the skin is smoother and brighter.

The invention relates to the technical field of cosmetics, and particularly discloses emulsion type foaming cleaning scrub cream with a skin care effect and a preparation method of the emulsion type foaming cleaning scrub cream. The scrub cream is prepared from the following raw material components in percentage by mass: 8 to 15 percent of glycerol, 0.2 to 0.9 percent of sodium hydroxide, 0.3 to 0.8 percent of citric acid, 0.03 to 0.2 percent of EDTA (Ethylene Diamine Tetraacetic Acid) disodium, 0.5 to 1.5 percent of an auxiliary agent, 1.5 to 3.0 percent of a thickening agent A, 1.5 to 3.0 percent of a thickening agent B, 5.86 to 1457 percent of an emollient, 12 to 22 percent of a surface active foaming agent, 0.8 to 3.0 percent of an emulsifying agent, 2.5 to 13 percent of a cutin stripping agent, 0.7 to 1.3 percent of a preservative, 0.32 to 0.92 percent of a skin conditioning agent and the balance of water, the skin conditioner is a mixture prepared from sodium hyaluronate, tocopherol, papain, nicotinamide, carnosine, panthenol and phytosterol oleate.

The invention relates to an anti-wrinkle and anti-aging composition and application thereof. The anti-wrinkle and anti-aging composition is prepared from hydrolyzed rice protein, a bifidus yeast fermentation product lysate, dipeptide diaminobutyryl benzyl amide diacetate, adenosine, hydroxydecyl ubiquinone, ceramide NP, palmitoyl tripeptide-5, carnosine and acetyl hexapeptide-8. According to the present invention, the components achieve the synergistic effect, such that the fibroblast proliferation can be promoted, the cell metabolism can be improved, the generation of collagen, elastin and the like can be promoted, the excellent oxidation resistance can be provided, and the effects of expression line inhibition, existing wrinkle fading and long-term aging resistance can be combined.

The present invention discloses a composition with a penetration-promoting effect and a preparation method thereof, wherein the composition with a penetration-promoting effect comprises a solvent, a phase A moisturizer, a phase B moisturizer, a phase C moisturizer, a pH regulator, a thickener, a solubilizing agent, a skin conditioner, and a plant extract; wherein the skin conditioner is a compound of a bifid yeast fermentation product filtrate, decarboxylated carnosine hydrochloride, a yeast fermentation product extract, and ergothioneine; wherein the plant extract comprises an baobab seed extract, an echinacea extract, and a wood apple extract. A preparation method of a composition with a penetration-promoting effect is to uniformly stir the components of the composition with a penetration-promoting effect to obtain a composition with a penetration-promoting effect. The present application has the effect of significantly improving skin permeability, promoting effective moisturizing ingredients to penetrate into the stratum corneum of the skin, replenishing moisture for the skin from an endogenous source, and lastingly moisturizing.

The invention discloses a gelatin-hyaluronic acid injectable hydrogel drug-carrying nanoparticle composite material as well as a preparation method and application thereof, relates to the technical field of biomedicine, and solves the problems that in the prior art, existing drugs for treating cartilage related diseases are difficult to deliver; the chronic inflammatory response in the articular cavity cannot be effectively controlled and cartilage cells cannot be protected at the same time, so that the application effect of the medicine is limited. The preparation method disclosed by the invention comprises the following steps: S1, obtaining a carnosine modified hyaluronic acid derivative Car-HA; s2, preparing nano particles (FNPs) loaded with fenofibrate; and S3, mixing the gelatin solution containing the FNPs with a Car-HA solution, adding transglutaminase into the mixed system, and carrying out an enzymatic cross-linking reaction to form the hydrogel FNPs-GelHA with a stable network structure. The CarHA and FNPs synergistic hydrogel strategy provided by the invention has good structural adjustability and drug adaptability, is suitable for delivery of various anti-inflammatory, anti-oxidation and cartilage repair drugs, and can be widely applied to local precise treatment of cartilage related diseases.

The invention relates to a decarboxylated carnosine derivative as well as a preparation method and application thereof. The structural formula of the decarboxylated carnosine derivative is shown as a formula (I), wherein R is selected from C5-C21 alkyl and C5-C21 unsaturated chain alkyl. Compared with decarboxylated carnosine, the decarboxylated carnosine derivative disclosed by the invention has a more excellent anti-saccharification effect; meanwhile, a relatively good anti-oxidation effect is achieved; moreover, the decarboxylated carnosine derivative disclosed by the invention has certain lipophilicity, is relatively easy to penetrate through a skin cuticle, is good in skin permeability and relatively good in stability, can be used for preparing cosmetics for resisting saccharification, resisting oxidation, resisting skin aging and the like, and has an important market value. # imgabs0 #

The invention belongs to the field of cosmetics, and particularly discloses an ormosia henryi bark extract-containing composition capable of nourishing, repairing and brightening skin as well as a preparation method and application of the composition. The composition comprises an active component, a solubilizer, polyol, phospholipid and water, wherein the active ingredients comprise an ormosia henryi bark extract, acetylchitosamine, decarboxylated carnosine or salt thereof and a coast pine bark extract. Active ingredients in the composition are good in solubility in the composition, the composition is good in stability, good in skin permeability and good in AGEs inhibition effect, the four active ingredients including the ormosia henryi bark extract, the acetylchitosamine, the decarboxylated carnosine and the coast pine bark extract are in mutual synergistic interaction, and an excellent unexpected technical effect is achieved.

The invention relates to the technical field of microorganisms, and particularly discloses a PhPepD mutant and application of the PhPepD mutant in fermentation production of L-carnosine. According to the invention, a new PhPepD mutant is screened by means of construction of a mutation library from PepD of different sources and error-prone PCR, site-directed saturation mutation and the like, the amino acid sequence of the PhPepD mutant is shown as SEQ ID NO: 18, and compared with wild type PhPepD protein, the PhPepD mutant has N158D / I176F / E393Q mutation. By using the mutant, a microorganism with increased L-carnosine yield can be obtained, and in recombinant microorganisms capable of producing carnosine without adding beta-alanine, the mutant also shows an effect of increasing the L-carnosine yield, and a new effective method is provided for industrial large-scale production of L-carnosine.

The invention discloses a method for improving soluble expression of non-ribosome peptide synthetase in escherichia coli. According to the method, a polyion oligopeptide label is connected to the N end or the C end of the non-ribosome peptide synthetase; the method comprises the following steps: adding a polyion oligopeptide tag (D) 5 at the N / C end of ebony in a fusion protein SGE formed by non-ribosomal peptide synthetase ebony for producing decarboxylated carnosine and phosphokinase Sfp through a connecting peptide GSG, or replacing a GSG sequence in an original SGE sequence with the polyion oligopeptide tag (D) 5 to construct new plasmids, and transforming the obtained three new plasmids in recombinant escherichia coli to obtain the decarboxylated carnosine-producing non-ribosomal peptide synthetase ebony-phosphokinase Sfp. The solubility of the non-ribosome peptide synthetase in escherichia coli is greatly improved, and the addition of the polyion oligopeptide tag (D) 5 at the N end is more beneficial to reducing the formation of inclusion bodies and improving the yield of decarboxylated carnosine.

The invention discloses a fermented caffeine eye cream composition. Comprising the following components in parts by weight: 30 to 80 parts of a fermentation composition, 1 to 5 parts of caffeine, 0.1 to 0.3 part of hydroxypropyl tetrahydropyrantriol, 0.5 to 2 parts of nicotinamide, 0.1 to 1 part of squalane, 0.01 to 0.5 part of a ceramide composition, 0.005 to 0.05 part of dipeptide diaminobutyryl benzyl amide diacetate, 0.005 to 0.05 part of a polypeptide composition, 0.01 to 0.5 part of carnosine, 0.01 to 0.5 part of tetrahydromethylpyrimidine carboxylic acid and 3 to 12 parts of a plant extract. The invention also discloses an eye cream containing the eye cream composition. The fermented caffeine eye cream composition provided by the invention can effectively smooth the skin surface, and is beneficial to preventing and comforting aging, improving skin elasticity, improving dark circles, relieving edema and removing under-eye puffiness.

The invention relates to the technical field of skin care products. The invention aims to provide a split storage type novel skin-brightening skin-care product combined by oligopeptide freeze-dried powder and essence. The split storage type novel skin-brightening skin-care product comprises multiple oligopeptide freeze-dried powder and solvent essence, the multi-oligopeptide freeze-dried powder is prepared from the following raw materials in parts by weight: 90 to 95 parts of water, 1 to 2 parts of glutathione, 1 to 2 parts of mannitol, 1 to 2 parts of carnosine, 0.5 to 1 part of ergothioneine, 0.5 to 1 part of vitamin C and 0.0005 to 0.001 part of a multi-peptide-zinc chelate. The multi-peptide-zinc chelate is prepared from the following raw materials in parts by weight: 1-2 parts of hexapeptide-2, 1-2 parts of nonapeptide-1, 1-2 parts of dipeptide-2, 1-2 parts of tripeptide-10 and 2-3 parts of zinc oxide. According to the invention, various peptides with small molecular weights are chelated with zinc, the characteristics of good permeability and strong skin affinity of the small molecular peptides are fully played, the effects of zinc and other components are effectively played, and the overall use effect is greatly improved. Through compounding of multiple components, the moisturizing and brightening mask has multiple effects of moisturizing, good permeability, whitening, brightening and the like.

The invention belongs to the field of daily chemicals, and discloses a composition with whitening and brightening effects, which comprises a whitening component, a component containing a plant cell culture or extract, and carnosine, the components containing the plant cell culture or extract comprise crithmum maritimum callus culture filtrate and leontopodium alpinum flower / leaf extract; the weight ratio of the crithmum maritimum callus culture filtrate to the leontopodium alpinum flower / leaf extract is (0.01-0.5): (0.01-5). The whitening component, the component containing the plant cell culture or extract and the carnosine are combined, so that the whitening effect and brightening effect of the whitening component can be improved, and the applicability of sensitive skin is improved. Meanwhile, the invention also provides application of the composition.

The invention provides a composition containing polydeoxyribonucleotide (PDRN) and sodium hyaluronate and application of the composition, and relates to the technical field of cosmetics and medical beauty. The composition is prepared from polydeoxyribonucleotide, sodium hyaluronate, L-carnosine, glycine, alanine, proline, vitamin B2, ergothioneine, Ectoine, a sophora flower bud extract, an aloe extract, butanediol and 1, 2-pentanediol. The composition is high in stability and has whitening and anti-aging effects.

The invention discloses a preparation method of a piezoelectric MOF (Metal Organic Framework) sound-sensitive agent with an ultrasonic response ROS / CO synergistic antibacterial function. The preparation method comprises the following steps: synthesizing a catechol modified ruthenium carbonyl carbon monoxide donor through a coupling reaction of 2, 4-dihydroxyl-1-phenylalanine and carbonyl ruthenium chloride; the preparation method comprises the following steps: mixing a carnosine aqueous solution and a metal ion aqueous solution in a solvent, and self-assembling the carnosine aqueous solution and the metal ion aqueous solution by a hydrothermal method to obtain a piezoelectric metal organic framework (PMOF); and modifying the carbon monoxide donor on the surface of the PMOF through a complexation reaction between metal ions on the surface of the PMOF and phenolic hydroxyl groups of the carbon monoxide donor to obtain the piezoelectric MOF sound-sensitive agent with ultrasonic response ROS / CO synergistic antibiosis. The invention also discloses the piezoelectric MOF sonosensitizer with ultrasonic response ROS / CO synergistic antibacterial effect obtained by the preparation method and application of the piezoelectric MOF sonosensitizer in preparation of sonosensitizer hydrophobic drugs and / or antibacterial agents. The sonosensitizer provided by the invention has excellent biocompatibility, can controllably start release of active oxygen and carbon monoxide through ultrasound to achieve synergistic antibiosis, enhances the antibacterial ability, and has excellent biological membrane penetrating ability.

The invention provides a peptide beverage capable of dispelling effects of alcohol, protecting liver and relieving fatigue and a preparation method and application thereof.The peptide beverage comprises hovenia dulcis thunb oligopeptide, walnut peptide, antioxidant peptide, energy release auxiliary peptide and the like, and the antioxidant peptide is prepared by mixing cordyceps militaris, sea-buckthorn and sunflower heads. The energy release auxiliary peptide is prepared from carnosine and arginine succinic acid peptide through microbial fermentation. The preparation method comprises the following steps: mixing the components according to a certain ratio, stirring, homogenizing, sterilizing and the like. The peptide beverage has the effects of dispelling the effects of alcohol, protecting the liver and relieving fatigue, and is suitable for preparing drugs or health-care products for dispelling the effects of alcohol and protecting the liver. The preparation method has the characteristics of strict raw material selection and fine preparation process, and ensures the quality and efficacy of the product. Through a scientific ratio and an advanced preparation technology, the peptide beverage provides a new choice for dispelling the effects of alcohol, protecting the liver and relieving fatigue, and has a wide market application prospect.