2351 results about "Succinic acid" patented technology

The invention discloses acid-resistant pichia kudriavzevii and an application of the acid-resistant pichia kudriavzevii. The acid-resistant pichia kudriavzevii is Pichia kudriavzevii S9 and is preserved in the Guangdong Microbial Culture Collection Center on September 20, 2024, and the preservation number of the acid-resistant pichia kudriavzevii S9 is GDMCC.No: 65148. The acid-resistant pichia kudriavzevii S9 has the advantages that the acid-resistant pichia kudriavzevii S9 is used for According to the invention, a low-pH-resistant pichia kudriavzevii strain is screened from surface microorganisms of grapes, and the pichia kudriavzevii strain can tolerate an environment with pH of 1.8 and ferment organic acid under the condition of not adding a neutralizing agent; besides, genetic modification is carried out based on pichia kudriavzevii, including knocking out succinic acid degradation related genes, knocking out ethanol and glycerol production pathways and enhancing succinic acid transporter expression, so that engineering bacteria for high-yield succinic acid are obtained, and the fermentation yield of succinic acid reaches 31.74 g / L under the condition that a neutralizer is not added.

The invention relates to an engineering bacterium of high-yield ornamental blue as well as a construction method and application of the engineering bacterium, and belongs to the technical field of natural dye synthesis by a biological method. The engineering bacterium capable of highly producing the ornamental blue, disclosed by the invention, expresses icd, bpsA, glnAY405F and gd hA; acnR, yggB, glsK, aceA and ldh are knocked out from the engineering bacteria. According to the application, yggB and aceA genes are knocked out, site-directed mutagenesis (Y405F) is carried out on a glnA gene, a glsK gene is replaced by a glnAY405F gene, an acnR gene is replaced by an icd gene, an ldh gene is replaced by a gdhA gene, and a bpsA gene is integrated, so that the formation of by-products such as lactate and succinic acid in a blue-viewing synthesis process can be blocked; the flow direction of a passage from citric acid to isocitric acid to alpha-ketoglutaric acid to glutamic acid to glutamine is improved, so that the concentration of glutamine in cells is improved, and the yield of the ornamental blue is improved.

Embodiments of the present invention provide methods and intermediates for the large scale preparation of 2, 4, 6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl] benzamide hemisuccinate, as well as formulations and product forms prepared by these methods. Embodiments of the present invention further provide for the preparation of lamidetan acetate (2, 4, 6-trifluoro-N-[6-(1-methylpiperidine-4-carbonyl)-2-pyridyl] benzamide acetate) and / or a pharmaceutical composition thereof, and / or the use of lamidetan acetate and formulations thereof in subcutaneous drug delivery.

The invention relates to the field of pesticide bactericides, and discloses a difluoromethyl thiazole amide-containing compound and application thereof as a bactericide. The difluoromethyl thiazole-containing amide compound has a structure as shown in a formula (I), and the difluoromethyl thiazole-containing amide compound with efficient activity on diseases such as rice sheath blight disease is designed by introducing a difluoromethyl thiazole-containing structure and a diphenyl ether fragment. The compound can be used as a brand new succinate dehydrogenase inhibitor or bactericide. # imgabs0 #

The invention relates to the technical field of concrete preparation, in particular to fiber-reinforced building solid waste recycled aggregate concrete and a preparation method thereof.The preparation method comprises the following preparation steps that S1, recycled coarse aggregate, slag, fly ash and river sand are mixed and stirred according to the proportion, and a cement mixture is obtained; s2, calcining the cement mixture for 2-3 hours to obtain cement clinker; s3, cement clinker, modified fibers, modified graphene oxide and tetrasodium iminodisuccinate are mixed according to the proportion and then poured into a stirrer to be stirred for 5-6 min; and S4, adding water into the stirrer according to the proportion, continuously stirring for 6-10 minutes, and taking out to obtain the fiber-reinforced building solid waste recycled aggregate concrete. According to the invention, the polystyrene fiber and the concrete are connected more tightly by using the modified fiber, and the polystyrene fiber can be subjected to multiple reactions with components in the concrete in an alkaline environment of the concrete to form a stable network structure, so that mechanical indexes such as crack resistance and breaking strength of the concrete are improved.

The preparation method comprises the following steps: firstly, uniformly stirring and mixing synthetic fluorophlogopite, silica, polymethylsilsesquioxane, boron nitride, bismuth oxychloride, zinc stearate, aluminum starch octenylsuccinate, mica, aluminum oxide, hydrolyzed sodium hyaluronate and toner in a stirring homogenizer; then uniformly mixing polydimethylsiloxane, octyldodecanol stearoyloxy stearate, isoamyl laurate, diisostearyl malate, phenoxyethanol and caprylyl glycol, and heating to 45 + / -5 DEG C; pouring the mixture into an oil spraying barrel of a stirring homogenizer, uniformly stirring and mixing while spraying oil, crushing, then carrying out airflow crushing, sieving the material, putting the sieved material into a mold plate, and carrying out compression molding, so as to obtain a pressed powder block; and putting the mixture into a packing material powder box to obtain the make-up fixing and brightening pressed powder. The pressed powder is prepared by adding an airflow crushing process, the particle size of the powder is smaller, the powder is dispersed more uniformly, the powder is pressed into the solid pressed powder, and the phenomenon of powder flying is well reduced while makeup fixing and brightening effects are achieved.

The invention relates to the field of cutting fluids, and discloses a high-hardness brittle semiconductor anti-deterioration cutting fluid and a production process thereof, the cutting fluid comprises the following components by weight: 15-25 parts of a lubricant, 10-20 parts of an anti-wear modifier, 1-5 parts of organic acid, 5-15 parts of organic amine, 1-3 parts of a lubricating antibacterial additive, 0.1-0.3 part of a bactericide, 0.5-2 parts of a wetting agent, 0.1-0.5 part of an antifoaming agent, and 25-35 parts of deionized water; the anti-wear modifier is prepared by taking aminated nano hexagonal boron nitride as a carrier to grow silicon dioxide nanoparticles in situ and carrying out composite hybridization on the silicon dioxide nanoparticles and binary acid ionic liquid, and the binary acid ionic liquid is prepared from 2-(1, 3-benzothiazole-2-sulfenyl) succinic acid and choline hydroxide; the lubricating antibacterial additive is prepared from aminated nano hexagonal boron nitride, chitosan and ethylene glycol diglycidyl ether, and by adding the anti-wear modifier and the lubricating antibacterial additive, the cutting fluid is endowed with excellent lubricating wear resistance, antibacterial property and anti-rust performance.

The invention relates to a starch-based soft capsule shell and a preparation method thereof. The starch-based soft capsule shell is prepared from the following raw materials in parts by mass: 60 to 70 parts of hydroxypropyl starch, 9 to 20 parts of carrageenan, 5 to 15 parts of diquat, 5 to 15 parts of polylysine, 5 to 10 parts of hydroxypropyl methyl cellulose acetate succinate, 15 to 20 parts of glycerol and 30 to 40 parts of pure water. According to the soft capsule shell, hydroxypropyl starch serves as a base material, gelatin is not added, the conditions of poor weather resistance and fishy smell caused by use of gelatin are avoided, through the synergistic effect of all the components, the defects that a starch-based material is poor in plasticity, fragile and insufficient in mechanical strength are overcome, the structural stability is enhanced through chemical crosslinking, and the mechanical strength is improved; and the mechanical property is improved by virtue of physical compounding, so that the low-temperature resistance, high-temperature resistance and mechanical strength of the capsule skin are improved.

The invention discloses a preparation method of antibacterial fibers and a fabric, and relates to the technical field of textile fabrics. When the antibacterial fiber is prepared, 1, 6-hexanediol, 2-(bromomethyl) diethyl succinate and diethyl 2, 2 ': 6', 2 '-terpyridine-4'-yl phosphonate are polymerized to prepare polyester; the preparation method comprises the following steps: reacting polyester with 7-(dimethylamino) coumarin to prepare modified polyester; the preparation method comprises the following steps: polymerizing maleic anhydride and methyl-vinyl polysiloxane and coating the surface of a phase change microcapsule with the maleic anhydride and the methyl-vinyl polysiloxane to prepare a pre-modified phase change microcapsule; the pre-modified phase change microcapsule and 1-hydroxymethyl-5, 5-dimethyl hydantoin are subjected to a reaction, and a modified phase change microcapsule is prepared; preparing a spinning solution from the modified polyester, the modified phase change microcapsules and copper chloride, performing electrostatic spinning, and performing chlorination finishing to obtain the antibacterial fiber. The antibacterial fiber prepared by the invention has excellent antibacterial, anti-aging, flame-retardant and mechanical properties.

The invention provides an adenosine dihydroxysuccinate eutectic crystal and a preparation method and application thereof.In the adenosine dihydroxysuccinate eutectic crystal, the molar ratio of a dihydroxysuccinic acid molecule to an adenosine molecule is 1: (1-4), on the premise that the structure of adenosine is not changed, dihydroxysuccinic acid and adenosine are combined, the water solubility of adenosine is improved, and therefore the adenosine dihydroxysuccinate eutectic crystal is obtained. According to the preparation method, the adenosine which is difficult to dissolve in water is prepared into the water-soluble adenosine dihydroxysuccinate eutectic crystal, so that the water solubility of the adenosine dihydroxysuccinate eutectic crystal can reach 4%, the effects of the adenosine dihydroxysuccinate and the adenosine monomer are not damaged, and the adenosine dihydroxysuccinate and the adenosine monomer have a better synergistic effect; compared with a monomer and a simple mixture, the composition has better effects in the aspects of antibiosis, antioxidation, anti-aging, hair care, hair loss prevention and the like, and has a good application prospect in skin and hair care products.

The invention discloses a high-stability iron-cerium flow battery and a preparation method of electrolyte, and belongs to the technical field of flow batteries. A positive electrolyte and a negative electrolyte are cerium salt and ferric salt, and are respectively mixed with nitrilotriacetic acid, ethylenediamine tetraacetic acid, trans-1, 2-cyclohexanediamine tetraacetic acid, 1, 3-propane diamine tetraacetic acid, N-(2-ethoxyl) ethylenediamine-N, N ', N'-triacetic acid, iminodiacetic acid, iminodisuccinic acid, succinic acid, N, N '-bis (2-hydroxyethyl)-N, N', N '-triacetic acid and N, N'-bis (2-hydroxyethyl)-N, N '-bis (2-hydroxyethyl)-N, N'-bis (2-hydroxyethyl)- N, N '-ethylenediamine disuccinic acid, aspartic acid or a derivative chemical thereof are coordinated to form an aqueous solution of the coordination compound. The positive electrolyte and the negative electrolyte are prepared from the same and equal chelating agent and supporting electrolyte, and the matching degree of the acid-base property of the positive electrolyte and the negative electrolyte is maintained; the auxiliary electrolyte is added, so that the viscosity difference between the positive electrolyte and the negative electrolyte is reduced, the transmembrane migration of water is reduced, and the conductivity is improved. The selected chelating agent is stably combined with iron and cerium, transmembrane transportation of active substances is inhibited, ion cross contamination among different electrolytes is reduced, and meanwhile side reactions are reduced. The price is low, and the charge-discharge performance and the cycle life of the iron-cerium flow battery are effectively improved at relatively low cost.

This application discloses a detergent tablet free of SLS surfactant and its preparation method. The detergent tablet includes a film-forming agent, an anionic surfactant, a non-ionic surfactant, a chelating agent, an enzyme preparation, an auxiliary agent and a essence. The film-forming agent includes one or more of polyvinyl alcohol, cellulose, and dodecenyl succinate starch ester. The anionic surfactant includes at least two of sodium α-olefin sulfonate, sodium fatty acid methyl ester sulfonate, and sodium hydroxyethyl sulfonate. The non-ionic surfactant includes at least two of fatty alcohol polyoxyethylene ethers, fatty acid methyl ester ethoxylate, and oil ethoxylate.

The invention provides a succinic acid composition as well as polyester and a polyester composite material prepared from the succinic acid composition. The succinic acid composition comprises succinic acid, a compound containing sulfate radicals and a phosphorus compound, the mass content of sulfate radicals in the succinic acid composition is 240 to 500 ppm; the mass content of the phosphorus element in the succinic acid composition is 0.5 to 40 ppm. According to the present invention, by compounding the sulfate radical-containing compound and the phosphorus compound with the specific content, the polyester is prepared by using the succinic acid composition as the raw material, such that the production efficiency of the polyester can be ensured, the polyester with characteristics of low acid value and high viscosity can be obtained, and the corrosion of the polyester or the composition thereof on the metal equipment can be reduced during the polyester composite material extrusion process; the quality of the polyester composite material is ensured.

The invention discloses a strain of bacillus acidophilus CNBG-PGPR-17 and an application of the bacillus acidophilus CNBG-PGPR-17. The invention further discloses a preparation method of the bacillus acidophilus CNBG-PGPR-17. The strain is preserved in the China General Microbiological Culture Collection Center (CGMCC) on October 28, 2021, the preservation number is CGMCC No.23673, and the strain is classified and named as bacillus acidogenes (Bacillus acidogenes). The strain is high in growth speed, good in stability and easy to amplify and culture; the inorganic phosphorus dissolving capacity is high, and the inorganic phosphorus dissolving amount can reach 277.8 mg / kg 7 days after inoculation; small molecular organic acids such as lactic acid and succinic acid can be secreted, and the pH of the solution is reduced; the contents of soil organic matters, soil total nitrogen, available phosphorus and quick-acting potassium can be increased, and the pH value of the soil is reduced; the growth of blueberry seedlings is promoted, and the blueberry quality is improved.

Composition for use in the prevention and / or treatment of a liver disease in a mammal, the composition comprising an active agent, said active agent containing the amino acids leucine, isoleucine, valine, threonine, lysine and the carboxylic acids citric acid, succinic acid, malic acid.

The invention provides a recombinant pichia kudriavzevii strain and application thereof, pichia kudriavzevii is taken as an original strain, and a reduced TCA pathway is introduced and comprises the following steps: overexpressing fumarate reductase FRD in the strain; weakening or inactivating an ethanol pathway, comprising: knocking out any one or a combination of at least two of encoding genes of ethanol dehydrogenase ADH1, ADH3 or ADH6; enhancing the PPP pathway in the pentose phosphate pathway of the strain, including: overexpressing glucose-6-phosphate dehydrogenase ZWF1 and / or 6-phosphogluconate dehydrogenase GND1; the method for reducing the activity of the malate dehydrogenase MDH2 in the TCA circulation pathway comprises the step of knocking out the coding gene of the malate dehydrogenase MDH2 in the TCA pathway. The pichia kudriavzevii is modified by using genetic engineering and metabolic engineering methods, so that the yield and the yield of succinic acid are increased, and the pichia kudriavzevii has important application prospects in industrial production.

The invention belongs to the technical field of preparation of blocking removers, and particularly relates to a composite chelating blocking remover for an oil field and a preparation method of the composite chelating blocking remover. The composite chelating blocking remover for the oil field is prepared from the following raw materials in percentage by mass: 7 to 9 percent of 1-butyl-3-methylimidazole dodecyl sulfonate, 5 to 7 percent of erucamide propyl hydroxypropyl sulfobetaine, 3 to 4 percent of di-(2-ethylhexyl) sodium sulfosuccinate, 4 to 5 percent of ethylenediamine di-o-hydroxyphenylacetic acid, 5 to 7 percent of N, N '-di (2-hydroxybenzyl) ethylenediamine-N, N'-bis (2-hydroxybenzyl)-N, N '-bis (2-ethylhexyl)-N, N'-bis (2-hydroxybenzyl)-N, N '-bis (2-hydroxybenzyl)-N, N'-bis (2-hydroxyphenyl)-N, N '-bis (2-hydroxyphenyl)-N, N'-bis (2-hydroxyphenyl)-N The cleaning agent is prepared from the following components in percentage by weight: 3 to 4 percent of N, N '-diacetic acid, 2 to 3 percent of O-(3-(benzyloxy) propyl) hydroxylamine, 1 to 2 percent of heptadecenyl hydroxyethyl imidazoline quaternary ammonium salt, 1 to 1.5 percent of dimethyl diallyl ammonium chloride homopolymer and the balance of water. The composite chelating blocking remover for the oil field has excellent scale dissolution rate and paraffin inhibition rate when being applied to complex scale blocking removal of the oil field.

The invention discloses an enzyme response type KRAS targeted protein degradation chimera as well as a preparation method and application thereof, and belongs to the technical field of tumor targeted therapy. The enzyme response type KRAS targeted protein degradation chimera disclosed by the invention is obtained by covalently linking three parts, namely a KRAS targeted protein degradation chimera, an enzyme response type amino acid sequence and a cell penetrating peptide amino acid sequence, wherein the KRAS targeted protein degradation chimera is obtained by linking a KRAS targeted peptide and a VHL E3 ligase ligand through succinic acid. The enzyme response type KRAS targeted protein degradation chimera releases the KRAS targeted protein degradation chimera under the action of ATG4 enzyme shearing, and shows a relatively strong lung cancer resisting effect in vitro and in vivo. The invention has significant advantages in the aspect of antitumor drugs, and opens up a new field for the development of targeted protein degradation chimera drugs. Enzyme response type KRAS targeted protein degradation chimera molecular structural formula as follows: # imgabs0 #

According to the environment-friendly scale and corrosion inhibitor for the green treatment of the circulating cooling water of the thermal power plant, the polyepoxysuccinate copolymer is synthesized, itaconic acid, sodium p-styrenesulfonate and sodium epoxysuccinate synthesized by maleic anhydride are adopted as monomers, sodium persulfate is adopted as an initiator, and a terpolymer IA / PESA / SSS is synthesized in a free combination manner; according to the optimal synthesis scheme, the molar ratio of IA to PESA is 4: 1, the molar ratio of PESA to SSS is 1: 4, the use amount of the initiator accounts for 2% of the mass of the monomer, the polymerization temperature is 95 DEG C, and the reaction time is 4 h. A dynamic simulation experiment shows that the copolymer is excellent in scale inhibition performance, and meanwhile, the synthesis evaluation is successful. According to the invention, the concentration ratio of the circulating cooling water is improved, so that the utilization ratio is improved, and the purpose of saving water is achieved; meanwhile, generation of scale substances is reduced, and high heat exchange efficiency is maintained; the corrosion condition of the system is relieved and prevented, safe operation of the system is kept, and safe and stable operation of the system is kept.

The invention relates to the technical field of welding materials, and discloses washable semiconductor solder paste and a preparation method and application thereof. The washable semiconductor solder paste comprises scaling powder and tin powder, wherein the mass ratio of the scaling powder to the tin powder is 1: (8-9.6); the soldering flux comprises the following raw material components: a film-forming agent, composite organic acid, a thixotropic agent, a surfactant, an antioxidant and a solvent, wherein the composite organic acid is composed of succinic acid and glutaric acid according to the mass ratio of (1-3): (1-2.5). According to the washable semiconductor solder paste, the particle size, the melting point and the alloy components of the tin powder are controlled, composite organic acid composed of succinic acid and glutaric acid in a specific proportion is adopted in the soldering flux, and other components are matched with one another; the tin powder and the soldering flux in a specific mass ratio are combined, so that the prepared washable semiconductor solder paste is good in wettability, the expansion rate is larger than or equal to 85%, the storage life reaches 3 months, and the washable semiconductor solder paste can be directly cleaned with water after being welded and is high in corrosion resistance and oxidation resistance.

The invention belongs to the technical field of contact lenses, and provides a moisturizing contact lens containing a hyaluronic acid coating and a preparation method of the moisturizing contact lens. The preparation method comprises the following steps: carrying out ultrasonic mixing on a hydrophilic monomer, a siloxane monomer, a cross-linking agent and an initiator, injecting the mixed solution into a contact lens mold, and carrying out polymerization reaction to obtain a contact lens material; mixing the chitosan solution, the shellac acid solution, the hyaluronic acid solution and the vitamin E succinate solution to obtain a hyaluronic acid mixed solution; and soaking the contact lens material in the hyaluronic acid mixed solution, adding a cross-linking agent, curing, and drying to obtain the moisturizing contact lens containing the hyaluronic acid coating. The contact lens disclosed by the invention has excellent moisture retention, good light transmission performance, swelling performance and excellent mechanical property, the wearing comfort is remarkably improved, and the contact lens is suitable for being worn for a long time; the preparation method disclosed by the invention is environment-friendly and easy to industrialize.

The invention discloses a preparation method of sturgeon roe peptide freeze-dried powder with an anti-aging effect. The preparation method specifically comprises the following steps: (1) unfreezing sturgeon roes, adding water, uniformly stirring, grinding and crushing, and adjusting the pH value; (2) heating and naturally cooling; (3) adding alkaline protease, uniformly stirring, carrying out enzymolysis, and adding starch sodium octenylsuccinate and vitamin E powder; (4) carrying out enzyme inactivation, naturally cooling, and adjusting the pH value; (5) carrying out rough filtration and centrifugal treatment, taking supernate, adsorbing, filtering and taking filtrate; and (6) carrying out plate frame filtration, taking filtrate, carrying out vacuum freeze drying, screening and packaging, thereby obtaining the product. The preparation method disclosed by the invention has the advantages of simplicity and convenience in operation, low cost, high embedding yield and the like, and has important significance in improving the stability and biological activity of the sturgeon roe peptide. Moreover, the sturgeon roe peptide freeze-dried powder has an anti-aging effect, and can be widely applied to oral liquid, solid beverages, tablet candies and the like in common foods.

The invention relates to a method for treating a waste iron phosphate positive electrode material by a phosphoric acid-hydrogen peroxide method matched with a specific complexing agent. The method comprises the following steps: crushing the positive electrode material of the waste lithium iron phosphate battery, adding the crushed positive electrode material into deionized water, and stirring to prepare slurry; heating the slurry, dropwise adding a phosphoric acid-hydrogen peroxide mixed solution and a complexing agent, adding a NaOH solution to adjust the pH value to 3.5, and filtering to obtain a filtrate and a filter cake; adding a NaOH solution into the filtrate, and adjusting the pH value to 10 to obtain lithium phosphate; performing evaporative crystallization on the filter cake to obtain trisodium phosphate; the complexing agent is prepared by adding pentasodium salt of amino trimethylene phosphonic acid, triallyl citrate, epoxysuccinic acid and DMF (Dimethyl Formamide) into a reaction kettle, mixing, adding ammonia water to adjust the pH value to be 10, and distilling to remove the DMF after the reaction is finished. The precipitation rate of Fe reaches up to 99.99%, the leaching rate of Li reaches up to 99.91%, and efficient separation and recycling of lithium and iron are achieved.

The application relates to an engineering bacterium for high yield of observation blue and a construction method and application thereof, and belongs to the technical field of biological synthesis of natural dyes. The engineering bacterium for high yield of observation blue expresses icd, bpsA, glnA Y405F and gdhA; the engineering bacterium knocks out acnR, yggB, glsK, aceA and ldh. By knocking out the yggB and aceA genes, performing site-directed mutation (Y405F) on the glnA gene, replacing the glsK gene with the glnA Y405F gene, replacing the acnR gene with the icd gene, replacing the ldh gene with the gdhA gene, and integrating the bpsA gene, the application can block the formation of by-products such as lactate and succinic acid in the observation blue synthesis process, improve the flow direction of the citric acid->isocitric acid->alpha-ketoglutaric acid->glutamic acid->glutamine path, and then improve the intracellular glutamine concentration, so that the yield of observation blue is improved.

The invention provides a tubular reaction device for succinic acid type polycarbonate polyether polyol, which is characterized in that a specific premixing unit and the structure and parameters of a reaction unit are designed in the tubular reaction device, and the premixing unit mixes all raw materials in a carbon dioxide bubbling manner; a tubular reactor in the reaction unit is provided with a dispersing sheet with a specific shape and holes, the one-time feeding production process of the succinic acid type polycarbonate polyether polyol is realized through cooperative control of a device structure and process parameters, the process steps are reduced, the process time is shortened, and the production efficiency is improved. The problems that in the prior art, succinic acid type polycarbonate polyether polyol is wide in molecular weight distribution, obviously large in molecular weight ratio target value and prone to implosion are solved, the succinic acid type polycarbonate polyether polyol is narrow in molecular weight distribution, the difference between the actual product molecular weight and the target theoretical value is small, the production process is safe, implosion is avoided, and the method is suitable for industrial production. And the method is suitable for industrial large-scale production.

The present application relates to a chelated iron desulfurizer, which is composed of a high-price soluble iron salt, a chelating agent, a pH buffer and water, wherein the chelating agent is a compound of sodium polyetheramine tetraacetate and at least one of N,N-diethylcarboxylic acid-based ethylenediamino-3-hydroxysuccinic acid, a polycarboxylic acid chelating agent or an amino acid-derived chelating agent; or the chelating agent is a compound of tetrasodium N,N-diethylcarboxylic acid-based ethylenediamino-3-hydroxysuccinic acid and at least one of sodium polyetheramine tetraacetate, a polycarboxylic acid chelating agent or an amino acid-derived chelating agent. Compared with the existing commonly used desulfurizers EDTA or NTA, the chelating ability of the present application's chelated iron desulfurizer is significantly improved, the iron ion regeneration ability is significantly enhanced, and the desulfurization effect is comparable to EDTA or NTA.

The invention belongs to the field of food preparation of non-alcoholic beverages, and particularly relates to a medicinal and edible solid beverage and a preparation method thereof. The medicinal and edible solid beverage comprises slow-release particles and functional drinks, the slow-release particles are prepared by performing enzymolysis on medicinal and edible substances by adopting immobilized bromelain and the like, performing microwave foam drying on an enzymolysis filtrate, and then encapsulating the filtrate with beta-cyclodextrin modified by starch sodium octenylsuccinate, the slow-release particles are brewed with boiling water, and the functional drinks are prepared into the medicinal and edible solid beverage. And bioactive compounds can be completely released within 15 minutes. The functional drink is an unstable foaming substance and can be used as a drinking prompt substance, and consumers are reminded to enjoy the solid drink with the best flavor in time by observing the dissipation condition of foam. The medicinal and edible solid beverage disclosed by the invention solves the problem that the optimal flavor of the existing solid beverage cannot be accurately transmitted to consumers, has relatively high sensory evaluation in the aspects of appearance, color, flavor and mouth feel, and also has a relatively good antioxidant effect.

The invention relates to bio-based 1, 4-butanediol and a preparation method thereof, and belongs to the technical field of chemical raw material synthesis. The preparation method of the bio-based 1, 4-butanediol comprises the following steps: preparing a bio-based 1, 4-succinic acid solution; continuously feeding the obtained bio-based 1, 4-succinic acid solution and hydrogen into a fixed bed containing a first-stage nickel-copper catalyst, and carrying out hydrogenation reaction to obtain a first-stage product; continuously feeding the obtained first-stage product and hydrogen into a fixed bed containing a second-stage nickel-copper catalyst, and carrying out hydrogenation reaction to obtain a second-stage product; and feeding the obtained second-stage product into a separation tower for separation and purification to obtain the bio-based 1, 4-butanediol. According to the method, the polymer-grade bio-based 1, 4-butanediol is prepared through continuous liquid phase hydrogenation of the bio-based 1, 4-succinic acid, the purity of the obtained polymer-grade bio-based 1, 4-butanediol is larger than or equal to 99.90%, and the product does not contain methyl-1, 4-butanediol and does not contain 2-(4-hydroxybutoxy)-tetrahydrofuran.

Mixed aliphatic-aromatic polyesters having suitable thermal properties and terminal acidity characterised by having a dicarboxylic component comprising at least three saturated aliphatic C4-C24 dicarboxylic acids, their C1-C24 alkyl esters, their salts and their mixtures, azelaic acid and succinic acid always being present.