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Malic enzyme may refer to decarboxylating malate dehydrogenases: Malate dehydrogenase or NAD-malic enzyme Malate dehydrogenase, another NAD-malic enzyme Malate dehydrogenase or NADP-malic enzyme including D-malate dehydrogenase
T cells with increased expression of malic enzyme 1 and uses thereof in cancer therapy
PendingUS20260176650A1ImmunoglobulinsVector-based foreign material introductionT cellCancer treatment
Methods and materials for increasing expression of malic enzyme 1 (ME1) in T cells are provided herein, as are compositions containing ME1 coding sequences or ME1 mRNA, and methods and materials for using T cells with increased ME1 levels to treat mammals having cancer.
Owner:MAYO FOUNDATION FOR MEDICAL EDUCATION & RESEARCH