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191 results about "Exponential growth" patented technology

Exponential growth is a specific way that a quantity may increase over time. It occurs when the instantaneous rate of change (that is, the derivative) of a quantity with respect to time is proportional to the quantity itself. Described as a function, a quantity undergoing exponential growth is an exponential function of time, that is, the variable representing time is the exponent (in contrast to other types of growth, such as quadratic growth).

Private multimedia network

Private Multimedia Network (PMN) complements, and is an improved alternative to digital videoconferencing and multimedia delivery systems. PMN's desktop and meeting room delivery system is designed to support the exponential growth of enterprise team-based initiatives. PMN provides “one-stop-shopping” for the full multimedia rubric. It delivers user-friendly control and cost/effective TV and broadcast quality videoconferencing and other multimedia services to organizations with “critical mass” campuses and building complexes. Though digital systems dominate the videoconferencing marketplace, PMN's hybrid digital/analog architecture has no digital peer in breadth or quality of service within or between campuses. The novel architecture leverages advances in analog video short-haul technology, digital long-haul technology, and telephony audio and control technology to deliver four-level multimedia services: 1) premise; 2) campus; 3) multi-site; and 4) ubiquitous (any site with ITU compatible multimedia equipment (e.g., videoconferencing) and communication links). On balance, the price/performance afforded by PMN's centralized Telco-based control and audio delivery combined with its decentralized broadcast quality video distribution raise videoconferencing and other multimedia services to a new level of ubiquity. Just as telephones and PC LANs, PMN delivers expensive Boardroom and mobile cart videoconferencing capabilities to every desktop via existing multimedia wall plates. The key phases for this invention are: Lip-synchronization across differing network communication links and protocols; Ubiquitous multimedia service; Cost/effective room and desktop deployment; Telco control and audio; Broadcast quality video; Isochronous Quality; Centralized control and distributed operation; and Interoperable architecture.
Owner:SORRELL JOHN D

Methods and organisms for the growth-coupled production of succinate

InactiveUS20070111294A1Stable growth-coupled productionFungiBacteriaMicroorganismSuccinic acid
The invention provides a non-naturally occurring microorganism comprising one or more gene disruptions encoding an enzyme associated with growth-coupled production of succinate when an activity of the enzyme is reduced, whereby the one or more gene disruptions confers stable growth-coupled production of succinate onto the non- naturally occurring microorganism. Also provided is a non-naturally occurring microorganism comprising a set of metabolic modifications obligatory coupling succinate production to growth of the microorganism, the set of metabolic modifications comprising disruption of one or more genes selected from the set of genes comprising: (a) adhE, ldhA; (b) adhE, ldhA, acka-pta; (c) pfl, ldhA; (d) pfl, ldhA, adhE; (e) acka-pta, pykF, atpF, sdhA; (f) acka-pta, pykF, ptsG, or (g) acka-pta, pykF, ptsG, adhE, ldhA, or an ortholog thereof, wherein the microorganism exhibits stable growth-coupled production of succinate. Additionally provided is a non-naturally occurring microorganism having the genes encoding the metabolic modification (e) acka-pta, pykF, atpF, sdhA that further includes disruption of at least one gene selected from pyka, atpH, sdhB or dhaKLM; a non-naturally occurring microorganism having the genes encoding the metabolic modification (f) ackA-pta, pykF, ptsG that further includes disruption of at least one gene selected from pykA or dhaKLM, or a non-naturally occurring microorganism having the genes encoding the metabolic modification (g) ackA-pta, pykF, ptsG, adhE, ldhA that further includes disruption of at least one gene selected from pykA or dhaKLM. The disruptions can be complete gene disruptions and the non-naturally occurring organisms can include a variety of prokaryotic or eukaryotic microorganisms. A method of producing a non-naturally occurring microorganism having stable growth-coupled production of succinate also is provided. The method includes: (a) identifying in silico a set of metabolic modifications requiring succinate production during exponential growth, and (b) genetically modifying a microorganism to contain the set of metabolic modifications requiring succinate production.
Owner:GENOMATICA INC

Methods and Organisms for Growth-Coupled Production of 3-Hydroxypropionic Acid

The invention provides a non-naturally occurring microorganism having one or more gene disruptions, the one or more gene disruptions occurring in genes encoding an enzyme obligatory coupling 3-hydroxypropionic acid production to growth of the microorganism when the gene disruption reduces an activity of the enzyme, whereby the one or more gene disruptions confers stable growth-coupled production of 3-hydroxypropionic acid onto the non-naturally occurring microorganism. Also provided is a non-naturally occurring microorganism comprising a set of metabolic modifications obligatory coupling 3-hydroxypropionic acid production to growth of the microorganism, the set of metabolic modifications having disruption of one or more genes including: (a) the set of genes selected from: (1) adhE, ldhA, pta-ackA; (2) adhE, ldhA, frdABCD; (3) adhE, ldhA, frdABCD, ptsG; (4) adhE, ldhA, frdABCD, pntAB; (5) adhE, ldhA, fumA, fumB, fumC; (6) adhE, ldhA, fumA, fumB, fumC, pntAB; (7) pflAB, ldhA, or (8) adhE, ldhA, pgi in a microorganism utilizing an anaerobic β-alanine 3-HP precursor pathway; (b) the set of genes selected from: (1) tpi, zwf; (2) tpi, ybhE; (3) tpi, gnd; (4) fpb, gapA; (5) pgi, edd, or (6) pgi, eda in a microorganism utilizing an aerobic glycerol 3-HP precursor pathway; (c) the set of genes selected from: (1) eno; (2) yibO; (3) eno, atpH, or other atp subunit, or (4) yibO, atpH, or other atp subunit, in a microorganism utilizing a glycerate 3-HP precursor pathway, or an ortholog thereof, wherein the microorganism exhibits stable growth-coupled production of 3-hydroxypropionic acid. The disruptions can be complete gene disruptions and the non-naturally occurring organisms can include a variety of prokaryotic or eukaryotic microorganisms. A method of producing a non-naturally occurring microorganism having stable growth-coupled production of 3-hydroxypropionic acid is further provided. The method includes: (a) identifying in silico a set of metabolic modifications requiring 3-hydroxypropionic acid production during exponential growth, and (b) genetically modifying a microorganism to contain the set of metabolic modifications requiring 3-hydroxypropionic acid production.
Owner:GENOMATICA INC

Method and system for finding a friend in a social network

A process for reducing the resources employed in real time to communicate a message between related nodes that are separated by multiple degrees of separation in a social network. At least a portion of the shortest path for the multiple degrees of separation between at least two related nodes in a social network is determined out of band prior to the initiation of a process to communicate between the related nodes. By pre-processing at least a portion of the degrees of separation for the shortest path between the nodes, the actual resources employed in real time to calculate the entire shortest path can be reduced. Typically, approximately fifty percent or more of the shortest paths for the degrees of separation between related nodes in the social network are pre-processed. Since the amount of resources for determining the shortest path for each degree of separation can exponentially increase with each degree, the pre-processing of a portion of the degrees of separation along a shortest path can significantly reduce the resources required in real time to complete the determination of the shortest path. Also, if a common intermediate node is identified in the pre-processing of the shortest paths for two nodes in the social network, the intermediate shortest paths can be stored for reuse as a complete shortest path between these two nodes,
Owner:R2 SOLUTIONS

Pcr-free sample preparation and detection systems for high speed biologic analysis and identification

Provided herein are biologic sample preparation and analysis systems that are rapid, portable, robust detection system for multiplexed detection of bio-threats, and which can be ruggedized to operate in harsh environments. A new method of detection called Combinatorial Probe Analysis (CPA), which provides an exponential increase in detection reliability, has been incorporated into these systems. This type of analysis greatly reduces false positives and false negatives; in addition it is reusable and eliminates special storage requirements for reagents. Specific technical advancements in the optimization of hybridization assays for nucleic acid detection on porous polymer monoliths (PPM) are also disclosed. Performing rapid and complete solubilization of viruses, vegetative bacteria and bacterial spores with an ultra high temperature solubilization protocol is also described. The systems provided herein provides the ability to perform rapid highly multiplexed analysis of a variety of bioagents, including bacteria viruses, and protein biotoxins. The systems and assays described herein are perform completely automated sample preparation and analysis, in a time frame of five minutes or less. The assay is simple in design allowing users in personal protective equipment to easily operate the system. The disclosed systems are robust, simple to use, and address the goals of the first responder community.
Owner:FLUIDIGM CORP

Method for extracting astaxanthin from haematococcus pluvialis

The invention belongs to the technical field of medicines, and relates to a method for extracting astaxanthin from haematococcus pluvialis. The method comprises the steps of culturing a seed stock solution in a glass apparatus with a drainage system, and carrying out later amplification culture of the haematococcus pluvialis and accumulation culture of the astaxanthin after 10-15 d; centrifuging a culture in an exponential growth period of seed culture; and inoculating cell clusters in a BBM basal medium to obtain a primary culture. The later accumulation culture of the astaxanthin is amplification culture by using a breathable plastic bag type simple device provided by the invention. In the accumulation stage, a stress culturing method is adopted to obtain a lab-scale test haematococcus pluvialis culture; and haematococcus pluvialis powder is obtained by spray drying. According to a preparation technology that extracts astaxanthin from the haematococcus pluvialis by adopting an ultrasonic cell disruption assisted mixed solvent extraction method, the haematococcus pluvialis powder is added in an organic solvent to carry out ultrasonic cell disruption, and then the astaxanthin is obtained by the steps of reflux extraction in a water bath, suction filtration, filtrate merging and concentration. Compared with a conventional direct extraction method, the method provided by the invention saves extraction time, and increases astaxanthin yield.
Owner:SHENYANG PHARMA UNIVERSITY

Laser three-dimensional imaging system based on human-vision-based simulated mechanism

The invention belongs to the field of laser three-dimensional imaging, and particularly relates to a laser three-dimensional imaging system based on a human-vision-based simulated mechanism. The system comprises a trigger, a pulse laser, an emitting optimal module, a non-even collection module, a signal processing module and a displayer. By adopting the non-even collection module, after a target is irradiated by the pulse laser, reflected or scattered pulse echoes pass through a first lens, a second lens and a third lens in sequence, and imaging is carried out on a probe array board. The probe array board is composed of a series of independent probes, wherein the number of probes in each ring is the same, the probes are annularly arrayed, each ring of probes and each corresponding adjacent ring of probes are in a tangent relation, adjacent pixels are in a tangent relation, the radiuses of the rings of probes increase exponentially, facula areas of the rings of probes increase exponentially, and accordingly variable-resolution-ratio target collection can be achieved; optical signals are converted to electric signals by a probe array, and the electric signals are read from inner rings to outer rings sequentially by the signal processing module in an annular switch-on mode. Fast and efficient data transmission is achieved.
Owner:BEIJING INSTITUTE OF TECHNOLOGYGY

Method for producing tetracycline by fermentation of streptomyces aureus

The invention relates to a method for producing tetracycline by fermentation of streptomyces aureus. The method comprises the following steps: slant spore culture, seed culture and fermentation culture of the streptomyces aureus, and is characterized in that dextrin, sucrose, corn pulp, hydrolyzed soybean meal and other medium-effect carbon-nitrogen sources are adopted to replace original late-effect carbon-nitrogen sources; by reducing the contents of starch and bean flour in an original fermentation culture medium and combining with a formula of a mixture in the fermentation process and adjustment of a replenishing method and placing part of the nitrogen sources in the fermentation culture medium into material replenishment in the fermentation process, the concentration of the culture medium in the fermentation process is effectively controlled, the oxygen dissolution condition in the early stage of fermentation is improved, the final residue of the culture medium of fermentation is controlled by material replenishment, the material consumption is reduced, and the emission of solid wastes is reduced; the metabolism velocity in exponential growth phase in the fermentation process of the tetracycline is effectively controlled, the abnormal situations that a fermentation solution turns red and becomes sour and the like in the fermentation process are reduced, and the fermentation level is improved.
Owner:NINGXIA QIYUAN PHARMA

Method for raising hydrogen production efficiency of microalgae

The invention discloses a method for raising hydrogen production efficiency of microalgae and belongs to the field of a biological energy source. The method comprises the following steps: hydrogen-production microalgae cells are cultured in a medium until the exponential growth phase; the microalgae cells are collected, and the microalgae cells are transferred to a microalgae hydrogen-production medium containing organic matters, deoxygenization and sealing are carried out, and the microalgae cells are continuously cultured in a dark environment for a certain time, wherein the organic matters contain at least one of glucose, fructose, acetate, pyruvic acid, 3-phosphoglycerate, malic acid and amino acid and at least one of sodium salts and sylvite of the above organic matters; and finally, the microalgae cells are again placed in a light environment to induce water decomposition to produce hydrogen. It is verified through experiments that hydrogen production efficiency of microalgae can be remarkably raised by adding the organic matters to the microalgae hydrogen-production medium. The method has characteristics of novel technology and remarkable effect and the like, is simple and reliable, and has important practical application value in the field of new energy.
Owner:NINGBO INST OF MATERIALS TECH & ENG CHINESE ACADEMY OF SCI
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