673 results about "Aqueous solubility" patented technology

The application discloses a method for rapidly and harmlessly treating phosphogypsum, and particularly relates to the harmless treatment technical field of industrial solid waste. The method comprises the following steps: mixing raw materials with an alkaline neutralizing agent, a trapping agent and an activating agent, adding a phosphorus solidifying agent and a fluorine solidifying agent, mixing, carbonizing and aging, and obtaining harmless phosphogypsum. The method adopts the alkaline neutralizing agent to rapidly neutralize free acid and improve the pH of the system; the trapping agent adsorbs heavy metals; the activating agent promotes As, Cd and the like to form a difficult-to-dissolve iron oxide gel or a precipitate; the phosphorus solidifying agent and the fluorine solidifying agent perform deep chemical precipitation to form a stable iron-calcium-phosphate / ferric fluoride composite solidified body. The functions of the agents are clear, and the agents have synergistic effects; the solidification effect of the agents on high water-solubility phosphorus, fluorine and various heavy metals is far better than that of a single or simply compounded agent system; and the leaching concentration can be reduced to a level far lower than the national standard.

This invention provides an inkjet recording method that enables the recording of images with minimal misalignment of grid lines, even when recording images using a recording head having overlapping sections where the end ejection ports of adjacent ejection port rows overlap. [Solution] An inkjet recording method comprising the step of discharging aqueous ink from end discharge ports constituting an overlapping portion, allocated to a first discharge port row and a second discharge port row, to record an image on a recording medium, wherein the viscosity of the aqueous ink is 4.0 mPa·s or more, and the water-soluble organic solvent contains a water-soluble organic solvent (A) with a vapor pressure of 0.030 Pa or more and 0.200 Pa or less at 25°C, and a water-soluble organic solvent (B) with a vapor pressure of 1.000 Pa or more at 25°C, wherein the content (mass%) of water-soluble organic solvent (A) is 0.30 times or more by mass ratio to the content (mass%) of water-soluble organic solvent (B).

This invention relates to the field of food preservation technology and discloses a liquid preservative for preserving fresh walnut kernels. The preservative comprises a natural preservative, a solubilizing and stabilizing agent, and a solvent. This liquid preservative uses natural phloretin as the preservative component, combined with Tween 80 as a solubilizing and stabilizing agent and ethanol as a solvent. This effectively solves the problems of poor water and oil solubility and inadequate stability of phloretin, allowing it to be stably dispersed in the preservative system and fully exert its antioxidant and antimicrobial effects. Furthermore, the preparation method is simple and easy to implement, and the production process is safe and controllable. It is convenient to use; the preservation of fresh walnut kernels can be achieved through dilution and soaking. The diluted solution can be reused, reducing usage costs. Simultaneously, it can inhibit bacterial growth during the storage of fresh walnut kernels, delay oxidative deterioration, maintain their good appearance and quality, extend shelf life, and meet the market demand for high-quality fresh walnut kernels.

This invention discloses a four-armed star-shaped polymer containing a polyoxyethylene structure, its preparation method, composition, and applications. The polymer is prepared by mixing an unsaturated organic carboxylic acid compound, an unsaturated sulfonic acid compound, and water, stirring to obtain a reaction solution, and continuously stirring and heating the reaction solution. An aqueous solution of a polyether macromonomer compound and the initiator aqueous solution are added to the heated reaction solution, followed by polymerization and purification. The polymer structure contains a large number of carboxyl groups, sulfonic acid groups, and ether groups, as well as abundant polyoxyethylene groups and alkyl chains, giving the polymer good water solubility and excellent chelating properties for metal ions. The polymer prepared by this method shows good effects in cleaning, defoaming, and scale inhibition. Furthermore, compositions formed by combining the polymer with other corrosion and scale inhibitors exhibit good compatibility and can be used for scale inhibition in high-hardness water.

The present application relates to the technical field of fluorescent dyes, in particular to an asymmetric pentamethine cyanine compound. The compound comprises a structure as shown in formula I. The compound provided by the present application has good water solubility, near-infrared absorption, high fluorescence quantum yield and good molar absorption coefficient, and can be used in nucleic acid labeling, DNA sequencing, cell imaging, protein labeling or specific recognition of amino acids.

This invention discloses a method for preparing hydrophilic drug nanoliposomes based on microfluidic-low-shear coupling double emulsion and the hydrophilic drug nanoliposomes prepared according to the following method: (1) Prepare aqueous solutions of hydrophilic drugs and chloroform solutions of soybean lecithin respectively; (2) Add the chloroform solution of soybean lecithin to the chamber as the oil phase, and inject the aqueous solution of hydrophilic drugs into the oil phase in the low-shear stirring field through a microtube under low-speed stirring and shearing, and collect the W / O pre-emulsion sample; (3) Use the W / O pre-emulsion sample as the dispersed phase, and inject it into the external aqueous phase in the same way as in step (2), and emulsify it under low-speed stirring and shearing to form a W / O / W double emulsion; (4) Remove the chloroform by vacuum evaporation of the W / O / W double emulsion to obtain hydrophilic drug nanoliposomes. The prepared Ganoderma lucidum polysaccharide nanoliposomes have a particle size controlled at 200-300 nm, a polydispersity index of about 0.2, and an encapsulation efficiency of more than 70%, which is more than twice that of the traditional thin film hydration method. It solves the technical problem of low encapsulation efficiency of water-soluble macromolecular Ganoderma lucidum polysaccharides.

This invention provides a drug-coated balloon catheter, its preparation method, and its application, relating to the field of medical device technology. The drug-coated balloon catheter includes a balloon catheter and a drug coating disposed on the surface of the balloon catheter; the drug coating includes an active drug and an excipient; the active drug is a flavonoid. The drug-coated balloon catheter utilizes flavonoids, which combine the advantages of low toxicity and high water solubility. While reducing the toxic side effects of the drug coating, it achieves rapid release and efficient absorption of the drug. Furthermore, through a dual mechanism of anti-proliferation and anti-inflammation, it effectively solves the problems of potential toxic side effects, limited transport efficiency, and limited functionality that may exist in existing products at high dose densities.

This invention provides a highly water-soluble composition for promoting autophagy and its application. The composition comprises 5-hydroxyflavone, acetylhydroxyproline, and a suitable solvent. This composition is a unique vesicular composition that enables efficient delivery and synergistic effects of the two active ingredients. It promotes autophagy, has improved solubility, stability, and antioxidant properties, and can prevent and repair skin photodamage at its source. This invention also discloses a method for preparing this composition and its applications.

The present invention refers to a method for manufacturing a phosphorylated lignin which is soluble in water at a pH range of 2 to 14. Said method comprises the efficient phosphorylation of lignin preventing the formation of undesired species, which leads to an outstanding water solubility at neutral and acidic conditions, and, preferably, the separation of the water-soluble phosphorylated lignin from the reaction medium, wherein said separation comprises acid precipitation and / or ultrafiltration and drying under specific conditions. The invention also refers to a phosphorylated lignin that is water- soluble at a pH of 2 to 14, preferably obtained by the method of the invention.

The present application discloses a kind of eggshell membrane water solution device and the production method using it, the device includes multiple containers, a liquid supply unit, a heating unit, a condensation recovery unit, a hanging unit, a microwave generating unit and a control unit, multiple the container is used to install different units respectively and is combined in stack mode, to make an eggshell raw material, a clean water and an enzyme in the container inside, heated to 50~70 DEG C for 6~12 hours, water vapor in the process is collected to become recovery water, the recovery water is used to flush the eggshell raw material to wash the water-soluble eggshell membrane remaining on the surface, air extraction and heating to 60~80 DEG C are carried out to reduce pressure concentration, finally using microwave destroys the protein bond of the egg membrane water solution and makes the enzyme inactivation;The foregoing action flow is automated to improve product quality and efficiency, and stack design can also improve the flexibility of configuration.

This invention proposes a Gynostemma pentaphyllum tea bag and its processing technology, belonging to the field of tea bag technology. The tea bag comprises the following raw materials in parts by weight: 60-80 parts Gynostemma pentaphyllum, 6-12 parts wild chrysanthemum, 5-10 parts Acer truncatum tea, 3-6 parts nervonic acid microcapsules, and 4-8 parts licorice. The processing technology includes: raw material pretreatment, chopping, segmented roasting, pulverizing, mixing, sterilization, and packaging. This invention, through a unique formula design, effectively improves the bitter taste of Gynostemma pentaphyllum using licorice and wild chrysanthemum; it increases the water solubility of nervonic acid by utilizing the wall structure of the microcapsules, solving the problem of its insolubility in water, allowing nervonic acid to be effectively dissolved in the tea infusion, achieving the effects of brain nerve protection and repair. Simultaneously, the microcapsule protection system ensures its dispersibility and stability in the processing system; through the combination of segmented roasting and ultra-fine pulverization, it not only alleviates the cold nature of Gynostemma pentaphyllum but also significantly improves the extraction rate of effective components.

The present invention relates to a temperature-responsive in situ gelling composition comprising an amphiphilic triblock copolymer of polyoxyethylene-polyoxypropylene-polyoxyethylene (PEO-PPO-PEO), a water-soluble hydrophilic polymer, wherein the composition further comprises at least one lipid agent. The lipid agent is selected from the group consisting of a phospholipid, a sterol, a glyceride, a fatty acid or ester and derivative, a fatty alcohol, a cholesterol and derivative or a combination of more than one lipid agent. The present invention further relates to a vascular embolization agent comprising the temperature-responsive in situ gelling composition.

The application discloses a photoresist stripping agent composition containing a sulfur alkyl single-head quaternary phosphonium salt quaternary phosphonium salt, a preparation method and application thereof. The composition comprises, in parts by weight, 1-5 parts of the sulfur alkyl single-head quaternary phosphonium salt, 65-75 parts of an organic solvent, 10-15 parts of an organic alcohol amine, 1.5-5 parts of a corrosion inhibitor, 0.1-0.5 parts of a defoaming agent and 1-2 parts of a wetting agent. The stripping agent has the advantages of fast stripping speed, strong stripping capacity, maintained stripping performance at a lower temperature, low corrosiveness to various substrates such as metals, silicon and silicon oxide, good water solubility, easy cleaning and good application prospect in the fields of semiconductor wafer cleaning and the like.

This invention discloses a low-temperature early-strength, low-viscosity liquid accelerator and its compounding and production process, relating to the field of concrete admixture technology. The accelerator is compounded from a basic skeleton component, a rheological stabilizing component, and a low-temperature early-strength component. The basic skeleton component includes an inorganic aluminum salt accelerator, anhydrous magnesium sulfate, diethanolamine, and water; the rheological stabilizing component includes liquid polyaluminum sulfate, an amphoteric internal salt viscosity reducer, and cationic nano-silica sol; the low-temperature early-strength component includes water-soluble organic aluminum salt, zirconium oxysulfate, lithium acetate, and water. This invention improves the rheological stability of the accelerator under low-temperature conditions through the combination of the amphoteric internal salt viscosity reducer and the cationic nano-silica sol; and improves the early strength development ability of the accelerator under low-temperature conditions through the combination of the water-soluble organic aluminum salt, zirconium oxysulfate, and lithium acetate.

The application discloses a high-water-solubility florfenicol powder and a preparation method thereof, and belongs to the technical field of veterinary drug preparations. The powder is prepared from florfenicol, a water-soluble polymer carrier, tetraethyl orthosilicate or a mixture of the tetraethyl orthosilicate and methyl triethoxysilane and a C2-C6 organic polyacid containing polyhydroxy and polycarboxyl groups as raw materials through in-situ sol-gel spray drying one-step method. In the preparation, the controllable hydrolysis and condensation of organosilane and the in-situ esterification cross-linking of the organic polyacid are used to synergistically assemble and build an organic-inorganic hybrid network skeleton, and the amorphous florfenicol is anchored in the network skeleton. The product has both instant and moisture-proof properties. The method is simple in process, and the raw and auxiliary materials are safe and easy to obtain, so the method is suitable for industrial production and solves the problem that traditional solid dispersions are easy to absorb moisture and form lumps.

The purpose of the present invention is to provide a composition which is for use in hydraulic materials and attains excellent storage stability. An aluminosilicate-containing composition according to the present invention contains an aluminosilicate, wherein the aluminosilicate is one obtained by reacting an aluminum-containing compound with a silicon-containing compound at a temperature of 30°C or higher in the presence of a water-soluble polymer having at least one functional group selected from among a carboxyl group, a phosphoric acid group, a sulfonic acid group, salts of these, and phosphoric ester groups.

A modified ethylene vinyl alcohol copolymer having a saponification degree of 70 mole% or more according to JIS K 6726 (1994); wherein the modified ethylene vinyl alcohol copolymer has monomer units containing carboxylic acid groups and monomer units containing lactam functional groups; wherein the modified ethylene vinyl alcohol copolymer has a 1 H-NMR spectrum, the integral area of the spectrum at 3.65 to 4.00 ppm is defined as 1, and the integral area corresponding to the spectrum at 2.05 to 2.35 ppm is 0.002 to 0.200; wherein the modified ethylene vinyl alcohol copolymer is subjected to thermal analysis by a differential scanning calorimeter, and the curve obtained by plotting the temperature as the X axis and the heat flow as the Y axis has a slope between -0.00100 and -0.00190 W / g°C at 100°C to the melting point Tm (°C). The modified ethylene vinyl alcohol copolymer of the present application is suitable for preparing a polyvinyl alcohol aqueous film. The present application also relates to a resin film and a water-soluble packaging.

The application discloses a kind of corrosion and scale inhibitor sulfur removal agent and preparation method thereof, belong to sulfur removal agent technical field, by weight parts including following components: hydroxyl alkyl amine modified triazine compound 30~60 parts, polyaspartic acid scale inhibitor 10~25 parts, sodium gluconate 5~15 parts, ethylenediamine tetramethylene phosphonic acid sodium 3~10 parts, organic phosphonic acid corrosion inhibitor 2~8 parts and water 20~40 parts;The hydroxyl alkyl amine modified triazine compound is prepared by triazine sulfur removal agent and N-methyl diethanolamine or diethanolamine under 50~80 ℃ for 2~4 hours, wherein the molar ratio of triazine sulfur removal agent and hydroxyl alkyl amine is 1:0.3~0.8.The application is prepared by using hydroxyl alkyl amine modified triazine compound as core sulfur removal component, triazine sulfur removal agent and N-methyl diethanolamine or diethanolamine are reacted under specific temperature and time, which greatly improves the capture activity and reaction rate of hydrogen sulfide, and improves water solubility and dispersibility, realizes efficient sulfur removal.

This invention discloses a guanylate cyclase-C (GC-C) activating peptide and its applications, belonging to the field of bioactive peptide technology. The amino acid sequence of the GC-C activating peptide is PFPGPIPN. The GC-C activating peptide of this invention can significantly activate GC-C activity, increasing intracellular cGMP levels. Furthermore, the GC-C activating peptide of this invention can alleviate constipation and abdominal pain symptoms in mice, thereby effectively preventing or improving irritable bowel syndrome (IBS). Therefore, the GC-C activating peptide provided by this invention has advantages such as high activity, safety and non-toxicity, and good water solubility. It can be used as a candidate molecule for alternative or adjuvant drugs in the clinical treatment of IBS, and also as a health product or food to improve constipation or abdominal pain.

The application provides a preparation method and application of resveratrol-polylactic acid microspheres, and relates to the technical field of biological agents, quantitative resveratrol is dissolved in methanol as O1 phase; quantitative polylactic acid is dissolved in an oil phase solution (ethyl acetate, dichloromethane, trichloromethane) as O2 phase; ammonium bicarbonate, sodium bicarbonate, sodium chloride and hydrogen peroxide are used as a porogen; O1 phase, O2 phase and the porogen solution are subjected to ultrasonic emulsification to obtain O / O primary emulsion; the O / O primary emulsion is added to a polyvinyl alcohol aqueous solution under stirring to obtain O / O / W multiple emulsion; the obtained O / O / W multiple emulsion is subjected to mechanical stirring to remove the oil phase solution in the O / O / W multiple emulsion, and then is subjected to standing, centrifugation, washing, drying and the like to obtain resveratrol-polylactic acid microspheres with uniform size. The resveratrol-polylactic acid microspheres of the application break through the bottleneck of poor water solubility of resveratrol, can effectively prolong the drug action time, and have good antibacterial effect.

The application discloses a tri-substituted tetrahydroisoquinoline amide derivative with a novel structure or a pharmaceutically acceptable salt thereof, which is a compound shown in formula I. The compound has a strong inhibiting capacity on immune cell migration, the compound itself has high permeability and good water solubility, and can be used as an immune cell migration inhibitor and used for developing a medicine for treating ophthalmic diseases such as dry eye.

The application discloses a preparation process of electronic-grade trans-1,2-cyclohexanediaminetetraacetic acid. The preparation process takes industrial-grade 1,2-cyclohexanediamine as raw material, reacts the 1,2-cyclohexanediamine with electronic-grade organic acid to generate a water-soluble salt, crystallizes at 0-30 DEG C, filters out the crystal to reserve the filtrate, adds an alkaline solution to the filtrate, then adds a polar organic reagent to extract, directly adds an aqueous bromoacetic acid solution to the oil phase to react, after the reaction is completed, adds electronic-grade dilute acid to precipitate trans-1,2-cyclohexanediaminetetraacetic acid until the PH of the system is less than or equal to 2, filters and reserves the solid, washes with pure water, and electronic-grade trans-1,2-cyclohexanediaminetetraacetic acid is obtained. The method has a clear process route, can effectively remove metal ion impurities in the synthesis process, the obtained trans-1,2-cyclohexanediaminetetraacetic acid product has high purity, can be used for preparing high-end semiconductor cleaning liquid, and meets the strict requirements of advanced processes on the purity of cleaning chemicals.

This invention pertains to microbial fermentation, specifically a method for preparing a fermentation broth containing β-1,3 / α-1,3-glucan. The method involves inoculating *Rhizobium spp.* into a sterilized fermentation medium containing carbon sources, nitrogen sources, and essential nutrients, followed by aerated fermentation. The carbon source in the fermentation medium is sucrose, and the nitrogen source is soy protein isolate. The aeration rate is controlled in stages, and nitrogen sources and hydrogen peroxide are supplemented during fermentation. This invention solves the problem of low fermentation yield in existing technologies, offering advantages such as high fermentation broth viscosity, a fermentation yield of 25 g / L to 30 g / L, and good water solubility of the prepared product.

The object of the present invention is to provide an oil-in-water emulsion cosmetic for mist spray that has excellent SPF boosting effect, good stability, and a fresh, non-sticky feel. [Solution] The present invention relates to an oil-in-water emulsion cosmetic composition for mist spray, comprising an aqueous clay mineral together with an ultraviolet absorber, wherein the aqueous clay mineral content is 1.0% to 5%, and which does not contain a water-soluble polymer or an ultraviolet scattering agent.

The present invention relates to: a water-soluble substituent-based novel compound having high solubility and a method for preparing same. The novel compound having high solubility of the present invention has repeating units represented by chemical formula 1, and has an excellent anti-inflammatory effect and an excellent effect on diseases caused by oxidative stress and neuroinflammatory diseases, and thus is useful as a health food or a pharmaceutical composition. [Chemical formula 1]

We provide a ground improvement agent that reduces CO2 emissions while improving the ground. [Solution] Seawater is electrolyzed to extract an acid (S1, S3), and an acid is added to calcium waste material to produce a calcium agent with higher solubility in water than the calcium waste material (S4). A ground improvement agent containing the calcium agent and slag powder derived from metal smelting is then applied to the ground (S6).

This invention provides a Panax notoginseng-Paris polyphylla supramolecular complex, its preparation method, cosmetic products, and applications. The Panax notoginseng-Paris polyphylla supramolecular complex is a complex formed by non-covalent bonding of Panax notoginseng extract (as the host molecule) and Paris polyphylla extract (as the guest molecule), with the host molecule encapsulating the guest molecule structure. The Panax notoginseng-Paris polyphylla supramolecular complex of this invention not only improves the water solubility of Paris polyphylla extract but also increases its skin permeability and reduces its cytotoxicity. The preparation method of this invention utilizes the synergistic effect of the active ingredients, resulting in strong compatibility and synergistic efficacy. It also slows down the release time of the active ingredients, extends their shelf life, and features a simple and easy-to-control process, stable granulation effect, and low production cost.

The application discloses a kind of phytosphingosine inclusions and its preparation method and application, belong to daily chemical technical field.The phytosphingosine inclusion of the application uses maltodextrin and gum arabic as embedding carrier, and the mass ratio of maltodextrin and gum arabic in embedding carrier is 1:1~3.The phytosphingosine of the application is modified by screening embedding carrier and optimizing embedding process, and the water solubility of the obtained phytosphingosine inclusion is significantly improved, which can increase the addition amount in daily chemical products, improve the skin care effect of moisturizing, repairing skin barrier and anti-aging, etc.The embedding carrier used in the application has good biocompatibility, no skin irritation, high safety;Moreover, the embedding process step is simple, without complex equipment, easy for large-scale industrial production, and the production cost is controllable, with good market application prospect.

The application belongs to the technical field of biological medical materials, and discloses a polydopamine modified modified nano-graphyne and a preparation method and application thereof. In the method, the polydopamine coating is combined with the nano-graphyne for the first time to construct a GDY@PDA composite system, and the core defects of the blocky graphyne, such as easy agglomeration, poor water solubility and insufficient biocompatibility, are solved. The graphyne-based material is applied to the near-infrared two-region photothermal regulation of neural cell calcium influx for the first time, the calcium ion channel is activated through the local thermal effect of the material, and precise, remote and reversible calcium influx regulation is realized; the limitation that the traditional biocompatibility modification is easy to fall off and difficult to functionalize is broken through, the polydopamine modification makes the material have both photothermal efficiency and biological safety, and the application of the graphyne in the treatment of neural diseases (such as neural cell injury repair) is expanded.