49 results about "Cyclodextrin polymer" patented technology

The invention discloses a method for improving the performance of a resistance reducing agent based on cyclodextrin solubilization modification and application, and belongs to the technical field of fracturing fluids. The method comprises the following steps: S1, preparing a mixed liquid from hydrophobic associated polymer dry powder and cyclodextrin; s2, stirring the mixed liquid, testing the particle size of the mixed liquid at the same time interval, and ending stirring after the particle size is reduced to a stable size, so as to obtain the hydrophobic associated polymer solution. The cyclodextrin polymer not only has a high-molecular effect, but also retains the inclusion ability of a cyclodextrin cavity, and has better inclusion performance under the condition of larger guest molecules. The hydrophobic association polymer is modified through a host-guest inclusion technology, the solubility of the hydrophobic association polymer is improved on the basis of guaranteeing the resistance reducing effect of the hydrophobic association polymer, and the prepared hydrophobic association polymer resistance reducing agent has the advantages of being fast in dissolution and good in shear resistance and resistance reducing effect.

The invention provides a preparation method of a novel heterogeneous Fenton-like catalytic material, i.e., a water-insoluble beta-cyclodextrin polymer is formed by esterification, polycondensation and crosslinking of citric acid and beta-cyclodextrin, and is combined with an iron-copper bimetallic catalytic active center through a metal coordination effect; a novel iron-copper beta-cyclodextrin polymeric material is successfully prepared and is used for catalyzing and activating H2O2 oxidized sulfonamide antibiotics SAs. Under the conditions that the temperature is 35 DEG C, the pH value is 3, the adding amount of the iron-copper beta-cyclodextrin polymeric material is 1.2 g / L, the adding amount of H2O2 is 10 mM, and the rotating speed of a stirrer is 500 r / min, the removal capacity of the iron-copper beta-cyclodextrin polymeric material Fenton-like system to 1 mg / L sulfameracil (SMR) is close to 90% within 10 min. The method provided by the invention has the characteristics of low cost, good effect, no generation of a large amount of iron mud, environmental protection and the like, is helpful for promoting the development of beta-cyclodextrin in the field of Fenton-like environment treatment, and provides an effective reference and a new thought for treatment of sulfonamide antibiotics in a water environment.

The invention discloses a zinc-bromine flow battery multifunctional bipolar plate and a preparation method and application thereof.The method comprises the steps that polyaniline is added into a cetyltrimethylammonium bromide ethanol solution, after stirring and ultrasonic treatment, a mixed solution is obtained and sprayed to the positive electrode side of a pretreated polypropylene bipolar plate, and after drying, the zinc-bromine flow battery multifunctional bipolar plate is obtained; the polyaniline modified polypropylene bipolar plate is obtained; the preparation method comprises the following steps: dissolving beta-cyclodextrin in a NaOH solution, adding epoxy chloropropane, stirring for reaction, washing to be neutral, drying, grinding and sieving to obtain a cyclodextrin polymer, dispersing the cyclodextrin polymer in a Nafion solution to obtain a cyclodextrin polymer solution, spraying the cyclodextrin polymer solution on the negative electrode side of a polyaniline modified polypropylene bipolar plate, and drying to obtain the multifunctional bipolar plate of the zinc-bromine flow battery. Polyaniline is loaded on the positive electrode side of the bipolar plate to reduce a bromine permeation source and bromine reaction activation energy, a cyclodextrin polymer Nafion solution is used for modifying and stabilizing the pH value of an electrolyte on the negative electrode side, uniform and compact deposition of zinc is promoted, formation of sharp dendrites is reduced, and the electrochemical performance and long-term stability of the battery are improved.

The invention discloses a salicylic acid-cyclodextrin-amino acid ternary inclusion compound and a preparation method thereof. The salicylic acid-cyclodextrin-amino acid ternary inclusion compound is formed by salicylic acid, amino acid and a cyclodextrin derivative through non-covalent bond interaction, the cyclodextrin derivative is a cross-linked beta-cyclodextrin polymer, salicylic acid molecules are included in a cavity of the cross-linked beta-cyclodextrin polymer, and the cross-linked beta-cyclodextrin polymer is a cross-linked beta-cyclodextrin polymer. And meanwhile, guanidyl or carboxyl of an amino acid side chain interacts with hydroxyl outside the cross-linked beta-cyclodextrin polymer or an exposed part of an included salicylic acid molecule. According to the invention, a cross-linked beta-cyclodextrin polymer is used, arginine is introduced as a synergist, a salicylic acid-cross-linked beta-cyclodextrin polymer-arginine ternary clathrate compound is constructed, and through charge neutralization and hydrogen bond network synergistic effect, clathration efficiency is significantly improved, and water solubility of salicylic acid is improved.

The invention belongs to the technical field of environmental remediation materials, and discloses preparation and application of a novel zero-valent iron-cyclodextrin polymer composite material with a nano-crack structure. The preparation method comprises the following steps: firstly preparing a novel cyclodextrin polymer material with enhanced confinement effect, and then regulating and controlling the liquid-phase reduction process of iron ions to prepare the novel zero-valent iron-cyclodextrin polymer composite material with a nano-crack structure. According to the cyclodextrin polymer preparation method based on the citric acid double-stage shearing effect, a confinement effect enhanced cyclodextrin polymer material is prepared, citric acid cooperates with cyclodextrin to enhance the binding and confinement regulation effect on Fe < 2 + > / Fe < 3 + >, and the occurrence form of Fe < 2 + > / Fe < 3 + > in a liquid phase system and the potassium borohydride reduction reaction process are regulated; the nano zero-valent iron material with a nano crack structure and better dispersity is prepared, and the reaction activity and the long-term effect of activating persulfate to degrade organic pollutants in water are improved. The preparation method of the material is easy to regulate and control and simple in step, and has practical application significance.

The invention provides a two-dimensional cyclodextrin polymer material as well as a preparation method and application thereof. The two-dimensional cyclodextrin polymer material is prepared by a method comprising the following steps: stirring a self-assembly agent and cyclodextrin molecules in a solvent, standing, and carrying out self-assembly to form a dispersion liquid with a sheet structure crystal; and mixing the dispersion liquid with a cross-linking agent, reacting, carrying out solid-liquid separation, washing and drying to obtain the product. The method is simple and convenient in preparation process, the two-dimensional cyclodextrin polymer with monomolecular layer thickness is obtained, and the method has considerable industrial application prospects. The invention also provides a two-dimensional cyclodextrin polymer material and application thereof.

The invention discloses a host-guest supermolecule dynamically linked alginate fiber and a preparation method and application thereof, alginate is used as a substrate, and the surface of the alginate is dynamically linked with a three-dimensional network structure formed by a beta-cyclodextrin polymer and an adamantane polymer through host-guest interaction. The fiber has excellent hydrogen peroxide selectivity and stability, not only can effectively produce hydrogen peroxide, but also is expected to be applied to multiple fields due to the unique fiber structure.

The invention is applicable to the technical field of environmental functional materials and pollution abatement, and provides a core-shell photocatalyst capable of efficiently degrading pollutants in water and a preparation method thereof.The photocatalyst takes TiO particles as a core structure and takes a high-swelling cyclodextrin polymer prepared through esterification cross-linking reaction of cyclodextrin and ethylenediamine tetraacetic acid dianhydride as a shell layer; and forming the core-shell structure composite material. Efficient enrichment and rapid degradation of organic pollutants in water are achieved through the adsorption-catalysis synergistic effect, and the method has the advantages of being environmentally friendly, excellent in performance, good in stability and wide in application prospect.

This invention discloses a cross-linked cyclodextrin polymer, its preparation method, and its applications, belonging to the field of compound synthesis and separation enrichment technology. This invention employs a Sonogashira coupling reaction to react α, β, and γ cyclodextrins with 2-, 3-, or 6-position fully iodine-substituted cyclodextrins with polyalkynyl groups, respectively, to obtain cross-linked cyclodextrin polymers with large specific surface areas and numerous cyclodextrin cavities. These polymers exhibit good separation effects for organic dyes, small organic molecule pollutants, and harmful components in cigarette smoke.

The application discloses a salicylic acid-cyclodextrin-amino acid ternary inclusion compound and a preparation method thereof. The salicylic acid-cyclodextrin-amino acid ternary inclusion compound is formed by non-covalent bond interaction of salicylic acid, amino acid and cyclodextrin derivatives, wherein the cyclodextrin derivative is a cross-linked beta-cyclodextrin polymer, wherein the salicylic acid molecules are included in the cavity of the cross-linked beta-cyclodextrin polymer, and meanwhile, the guanidino group or carboxyl group of the amino acid side chain interacts with the hydroxyl group outside the cross-linked beta-cyclodextrin polymer or the exposed part of the salicylic acid molecules after inclusion. The application uses the cross-linked beta-cyclodextrin polymer and introduces arginine as a synergist to construct a salicylic acid-cross-linked beta-cyclodextrin polymer-arginine ternary inclusion compound, and through charge neutralization and hydrogen bond network synergistic effect, the inclusion efficiency is significantly improved, and the water solubility of salicylic acid is improved.

The present invention provides an acid-resistant nano-polymer microsphere inclusion plugging system and its preparation method and application. The plugging system of the present invention is prepared by including the following raw materials in parts by mass: 1-5 parts of acid-resistant nano-polymer microspheres, 1-5 parts of acid-resistant low-molecular-weight cyclodextrin polymers, and 80-120 parts of water. The present invention introduces the idea of ​​supramolecular construction, and proposes an inclusion-enhanced plugging system constructed by the host-guest inclusion action of acid-resistant nano-polymer microspheres and cyclodextrin polymers through the design of the surface molecular structure of nano-polymer microspheres and the molecular structure of cyclodextrin polymers. The plugging system of the present invention has strong acid resistance and excellent shear resistance, wherein the nano-polymer microspheres have good dispersibility, good injectability, and are easy to be injected into the formation and migrate to deep; at the same time, they have the characteristics of low concentration and high efficiency, can effectively enter the deep formation and efficiently achieve the plugging of cracks, thereby increasing the swept volume and displacement efficiency of CO2.

The application belongs to a kind of adsorbent and its preparation method, application, for cyclodextrin in adsorbing dye wastewater, it is difficult to separate from solution after dye molecule, limit the recycling use and convenience of cyclodextrin technical problem, provide a kind of boric acid-cyclodextrin polymer adsorbent and its preparation method, application, only need to mix boric acid and cyclodextrin and dissolve, then heat, drying can obtain boric acid-cyclodextrin polymer adsorbent, preparation process is carried out in water, does not need to add any organic solvent or crosslinking agent, green environmental protection, preparation process is simple and easy to operate, does not need complicated and lengthy step, as raw material, boric acid and cyclodextrin source is simple, low cost, has wide use in industry and medical field.

The present invention provides a surfactant-based CO2 flooding reservoir heterogeneous supramolecular inclusion synergistic system and its preparation method and application. The supramolecular inclusion synergistic system of the present invention comprises the following raw material compositions in parts by mass: 0.1-0.2 parts of acid-resistant hydrophobic polymer microspheres, 1-2 parts of acid-resistant cyclodextrin polymers, 1-3 parts of surfactants, and 800-1200 parts of water. The heterogeneous supramolecular inclusion synergistic system of the present invention has acid resistance and good stability, and is stable under supercritical CO2 acidic conditions (pH is about 2-3); it has shear recovery, and the viscosity of the system is reduced under high shear conditions during injection, making it easy to inject, and supramolecular action occurs underground to achieve in-situ viscosity increase. The heterogeneous supramolecular inclusion synergistic system of the present invention can effectively achieve the blocking of gas channeling channels, with good blocking effect, thereby being able to improve the swept volume and displacement efficiency of CO2.

The invention belongs to the field of preparation of polysaccharide antibacterial agents, and discloses a cyclodextrin polymer microcapsule capable of realizing controlled release of silver nanoparticles through gelatinization, and a preparation method of the cyclodextrin polymer microcapsule comprises the following steps: firstly, synthesizing a porous crystal of a cyclodextrin metal organic framework in which the silver nanoparticles are uniformly dispersed in one step through a strategy of synergistic nucleation growth induction multi-core packaging; and then cross-linking to obtain the cyclodextrin polymer microcapsule capable of controlling the release of the silver nanoparticles through gelatinization. According to the synthesis strategy, all the silver nanoparticles are limited in cyclodextrin skeleton pore channels of the porous crystal, the problem that the silver nanoparticles are loaded on the surface of the cyclodextrin polymer microcapsule is avoided, and the silver nanoparticles are small in size and uniform in distribution; the prepared microcapsule is gelatinized when encountering water, controllable release of the silver nanoparticles can be achieved, and the microcapsule has good application potential in the fields of antibiosis, catalysis, pollutant detection and the like.

The application discloses a preparation method and application of a cyclodextrin polymer composite adsorbing material. The preparation method of the adsorbing material comprises the following steps: under the action of NaH, β-cyclodextrin is subjected to hydroxyl activation, then maleic anhydride is slowly added to carry out a reaction, and thus a β-cyclodextrin-dibutenedioic acid ester derivative is prepared; under the action of an initiator and a crosslinking agent, the β-cyclodextrin-dibutenedioic acid ester, a double-bond-containing monomer and a functional monomer are subjected to a polymerization reaction, and then are washed and dried, so as to obtain the cyclodextrin polymer composite adsorbing material; the functional monomer is silanized montmorillonite or Fe3O4-dibutenedioic acid ester; and the double-bond-containing monomer is one of acrylic acid, acrylamide and styrene. The cyclodextrin polymer composite adsorbing material with multiple action sites is prepared by using β-cyclodextrin and the functional monomer as raw materials, and by utilizing the structural advantages of different compounds; the preparation conditions of the obtained composite material are mild, the post-treatment is simple, and the composite material has high adsorbing efficiency as an adsorbent.

The application discloses a method for improving the performance of a resistance reducing agent based on cyclodextrin solubilization modification and application, and belongs to the technical field of fracturing fluids, and comprises the following steps: S1, mixing a hydrophobic associated polymer dry powder and cyclodextrin to prepare a mixed liquid; S2, stirring the mixed liquid, and testing the particle size in the mixed liquid at the same interval of time; and ending the stirring after the particle size is reduced to a stable size, so as to obtain a hydrophobic associated polymer solution. The cyclodextrin polymer not only has a high molecular effect, but also retains the inclusion ability of the cavity of the cyclodextrin, and has good inclusion performance in the case that the guest molecules are large. The hydrophobic associated polymer is modified through host-guest inclusion technology, the solubility of the hydrophobic associated polymer is improved on the basis of ensuring the resistance reducing effect, and the prepared hydrophobic associated polymer resistance reducing agent has the advantages of fast dissolution, good shear resistance and good resistance reducing effect.

The invention discloses a safe and environment-friendly water-based paint and a preparation method thereof.A methoxy group on a red molecular structure of pigment 146 is modified into a phenolic hydroxyl group through a chemical modification method; the modified 146 red with the phenolic hydroxyl group is introduced in the process of synthesizing polyurethane, and the pigment is combined with resin in a chemical bond mode, so that the physical resistances such as adhesion, hardness and water resistance of the pigment on a base material can be greatly improved. The essence polymer is prepared by using cyclodextrin coated essence as a seed phase and carrying out in-situ polymerization to obtain an essence-cyclodextrin-polymer; meanwhile, the same essence is introduced into a monomer dropwise adding phase, so that volatilization of the essence in the high-temperature polymerization process can be effectively inhibited, and the embedding effect of cyclodextrin on the essence is ensured. When the essence polymer is used as an essence adding system of the water-based paint, the long-range essence release property of the water-based paint can be effectively controlled.

The present disclosure relates to anionic cyclodextrin polymer- and chitosan-based hydrogel compositions for use in the treatment of joint disorders. In particular, the hydrogel combines a pharmacological action, in particular an analgesic action, with viscosupplementation (lubrication action).

The invention discloses a polyferric chloride high-efficiency water purifying agent and a production process and application thereof, and belongs to the technical field of water purifying agents, the polyferric chloride high-efficiency water purifying agent is of a polymer inclusion structure; the polyferric chloride high-efficiency water purifying agent comprises polyferric chloride and a beta-cyclodextrin polymer matrix loaded with the polyferric chloride. Through beta-cyclodextrin polymer matrix carrier loading, the stability of polyferric chloride can be effectively improved, a polymer inclusion structure can integrate the advantages of a polymer matrix and polyferric chloride, good stability and structure adjustability are achieved, the advantages of the polymer matrix and the polyferric chloride can be integrated, the sewage treatment capacity is improved, and the sewage treatment efficiency is improved. The utilization rate of polymerization ferric chloride is effectively improved. In addition, polypropylene glycol block copolymerized polyethyleneimine can be compounded in a beta-cyclodextrin polymer matrix, so that the charge neutralization and adsorption bridging effects of polyferric chloride can be enhanced, and heavy metal ions in sewage can be chelated, so that the water purification effect and the water purification efficiency are improved, and an efficient water purification agent is obtained.

The invention belongs to the technical field of development of water treatment adsorbents, and discloses a large-scale preparation method and application of a cyclodextrin polymer adsorbent based on a citric acid two-stage shear effect, and the preparation method comprises the following steps: adding an epichlorohydrin (EPI) cross-linking agent in two stages, inhibiting and relieving the self-polymerization process of the cross-linking agent, and preparing a cyclodextrin polymer adsorbent. The covalent binding of cyclodextrin CD and EPI is promoted to generate a cross-linked structure unit; citric acid serving as an EPI polymerization reaction shearing agent is synchronously added in the two stages, the citric acid induces EPI to be subjected to ring-opening reaction to inhibit the auto-polymerization process of the EPI, the rate and disorder of cross-linking polymerization reaction of the EPI and CD are reduced, and the cyclodextrin polymer material with regular morphology is prepared. According to the method, rapid preparation of kilogram-level cyclodextrin polymer by single feeding is realized, and the prepared novel cyclodextrin polymer adsorbent with multiple binding sites and a regular spherical structure can adsorb organic pollutants and heavy metal ions in water. The preparation method is easy to regulate and control, simple in step and wide in application prospect.

The invention relates to the technical field of cleaning agents, in particular to a medical rapid low-foam multi-enzyme cleaning agent and a preparation method thereof. The cleaning agent is prepared from propylene glycol, borax decahydrate, phenylboronic acid cross-linked polymer gel dispersion liquid, a double-grafted cross-linked beta-cyclodextrin polymer aqueous solution, a low-foam surfactant, composite multi-enzyme liquid, calcium chloride, a polydimethylsiloxane defoaming agent, essence and the like. The preparation method is realized through multi-step polymerization, step-by-step dispersion and key component addition. By adopting the synergistic effect of the reversible borate micro-network, the double-grafted cyclodextrin and the polyethylene glycol / tannic acid and combining the siloxane defoaming and low-foam surface activity system, the foam height is obviously reduced, the foam persistence is inhibited, the multi-enzyme synergistic stability is improved, and rapid and efficient decontamination is realized. The formula has good adaptability to hard water, and is suitable for the rapid and standardized cleaning process of medical instruments, especially endoscopes and spray cleaning equipment.

The invention discloses a bio-based super absorbent for a dispersible sanitary towel and a preparation process of the bio-based super absorbent. The water absorbent is prepared by compounding functional polysaccharides such as sodium alginate, carboxymethylated pea protein, octenyl succinic starch ester and gellan gum with structured auxiliaries such as porous cyclodextrin polymer, nano kaolin, calcium hydrogen citrate and tartaric acid. The preparation process creatively adopts a pre-assembly dry method compounding and fluidized bed trigger type synchronous crosslinking-pore forming integrated technology, and the core is that calcium hydrogen citrate is utilized to synchronously generate CO and Ca in situ under the triggering of acid, and an ideal structure with gradient crosslinking core-shell and through open micropores is constructed by a one-step method. And the obtained product has the advantages of high water absorption rate, high multiplying power and strong pressure maintaining capability, and can be completely biodegraded.

The present invention discloses a method for preparing a hybrid supramolecular fluorescent nanoprobe system, comprising the following steps: (1) preparing a β-cyclodextrin polymer; (2) preparing an adamantane-derivatized nucleic acid aptamer; (3) preparing an adamantane-derivatized folic acid; (4) preparing a self-assembled supramolecular fluorescent nanoprobe targeted by a nucleic acid aptamer; (5) preparing a self-assembled supramolecular fluorescent nanoprobe targeted by a folic acid; (6) mixing the nanoprobes prepared in step (4) and step (5) to obtain a hybrid supramolecular fluorescent nanoprobe system. The present invention successfully constructs two supramolecular fluorescent nanoprobes based on a self-assembly method, and the hybrid probe system composed of the two can not only effectively distinguish human lung adenocarcinoma cells, activated macrophages and normal cells, but also can successfully distinguish lung adenocarcinoma areas, inflammatory areas and normal areas in paracancerous tissue sections, providing valuable detection methods and technical support for the diagnosis of lung adenocarcinoma.

The invention provides well cementation flushing fluid and a preparation method thereof, and belongs to the technical field of flushing fluid, and the preparation method comprises the following steps: dissolving benzyl quaternized cyclodextrin and benzyl dichloride in [BMIm] Cl / FeCl3 ionic liquid, stirring at high temperature, filtering, washing, Soxhlet extraction and vacuum drying to obtain a porous cyclodextrin polymer; dissolving a porous cyclodextrin polymer in water, standing, adding silanized SiO2 nanoparticles, mixing, stirring, filtering, and drying in vacuum to obtain a SiO2 / porous cyclodextrin polymer composite material; monoethanolamine, sodium cocoyl aminopropionate and water are mixed and stirred, the SiO2 / porous cyclodextrin polymer composite material is added, high-speed stirring is performed, and the well cementation flushing fluid is prepared. The prepared well cementation flushing fluid has good compatibility with drilling fluid and cement paste, can be used for flushing residual drilling fluid and filter cakes of well walls and casing walls in well cementation cementing operation, and has certain high temperature resistance.

Disclosed herein are mesoporous polymeric materials and methods for preparing and using the same. The mesoporous polymeric material comprises a network of cyclodextrin moieties crosslinked by a plurality of crosslinks.

The invention relates to the technical field of biomedical materials, and discloses an injectable biocompatible hydrogel based on dynamic supramolecular assembly, and the hydrogel comprises the following components by weight: 3.0-5.0% of zinc oxide nanocrystalline regenerated cellulose; 3.0%-5.0% of chondroitin sulfate; 1.5% to 2.5% of recombinant human source collagen; 1%-2% of beta-sodium glycerophosphate; 0.7%-1% of a cyclodextrin polymer; 0.4%-0.7% of an adamantane derivative; 0.3% to 0.5% of PEI-DNA nano particles; 0.1% to 0.3% of calcium citrate; 0.1% to 0.2% of sodium alginate microspheres; 0.15%-0.2% of a pH buffer agent; the preparation method comprises the following steps: taking collagen as a raw material, taking sterile deionized water and normal saline as residual components, and adjusting the components through subject-object supramolecular interaction, ionic crosslinking, collagen thermosensitive assembly and a step-by-step mixing process and structure, so that the prepared hydrogel has the advantages of dynamic reversible crosslinking, shear thinning and self-healing synergy, high biocompatibility and controllable degradation rate.

The invention relates to the field of veterinary drugs, in particular to veterinary water-soluble florfenicol powder and a preparation method thereof. Comprising florfenicol, an inclusion agent and a dispersing agent, the inclusion agent is selected from beta-cyclodextrin, hydroxypropyl beta-cyclodextrin and a water-soluble cyclodextrin polymer, the water-soluble cyclodextrin polymer is water-soluble epoxypropane cross-linked cyclodextrin, and the molecular weight of the water-soluble cyclodextrin polymer is 1t; 100,000, 20,000, 20,000, 20,000; the dispersing agent is selected from povidone K30, polyethylene glycol, poloxamer 188 or sodium carboxymethyl cellulose. The preparation process is simplified, and the preparation method is suitable for large-scale industrial production; the production cost is greatly reduced; meanwhile, the water solubility of florfenicol is improved, the water solubility reaches up to 10000 ppm, and the prepared product is good in water solubility, safe and reliable and does not affect the health of animals.

Methods and kits are provided for an assay for detecting and quantifying a PFAS compound or a mixture of PFAS compounds in a sample. The method includes the steps of providing a solid cyclodextrin polymer adsorbed on or linked to a substrate, contacting an indicator molecule with the solid cyclodextrin polymer or the cyclodextrin adsorbed on or covalently linked to the substrate to form a complex, contacting the complex with the sample and measuring a parameter of the indicator molecule. The parameter is correlated with displacement of the indicator molecule from the solid polymerized cyclodextrin or the cyclodextrin adsorbed on or covalently linked to the substrate upon binding of the PFAS compound to the cyclodextrin, thereby indicating presence and quantity of the PFAS compound or the mixture of PFAS compounds in the sample.

The invention discloses a method for extracting and detecting microcystic toxins in water, and belongs to the technical field of water quality detection.The method comprises the steps that cyclodextrin and a compound with a quaternary ammonium salt structure are polymerized, and a porous cyclodextrin polymer with cations is obtained and serves as a cation modified solid-phase extraction column; the covalently-bound and non-covalently-bound microcystic toxins are converted into free microcystic toxins through enzymolysis and the cation modified solid-phase extraction column, the recovery rate is high, and the detection accuracy is improved.

The invention belongs to the technical field of nano-drugs, and particularly relates to an ultrasonic responsive apoptosis bionic targeting nano-carrier delivery material and a preparation method thereof. According to the invention, a beta-cyclodextrin polymer (PCD) is used as a core skeleton, and phosphorylserine (PS) is modified through a phosphate bond so as to enhance the targeting ability; pFH (perfluorohexane) is entrapped as an ultrasonic response core under a low-temperature condition by utilizing interaction of a subject and an object; liposome (soya bean lecithin and cholesterol) is used for outer layer coating, so that the in-vivo stability and the circulation half-life period of the system are remarkably improved, and the breakthrough of the PCD-PS system from local administration to systemic administration is realized for the first time; the system has excellent ultrasonic responsiveness, and can be accurately triggered at a targeted part and release contents; meanwhile, the apoptotic cell imitating design endows the system with active targeting property, and the dual-coating structure ensures the stability of in-vivo circulation, so that the synergistic interaction of stable circulation, active targeting and ultrasonic triggering is realized.