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259 results about "Inclusion compound" patented technology

In host–guest chemistry, an inclusion compound is a complex in which one chemical compound (the "host") has a cavity into which "guest" compound can be accommodated. The interaction between the host and guest involves purely van der Waals bonding. The definition of inclusion compounds is very broad, extending to channels formed between molecules in a crystal lattice in which guest molecules can fit.

Polyphosphate flame retardant with high thermal stability and preparation method thereof

The invention belongs to the technical field of flame retardants, and particularly relates to a high-thermal-stability polyphosphate flame retardant and a preparation method thereof. The DOPO is modified through the polyethylene glycol acrylate, methyl methacrylate and dicumyl peroxide composite solution, double bonds of the polyethylene glycol acrylate and P-H bonds of the DOPO can be subjected to nucleophilic addition to form stable C-P bonds, and thermal migration of the DOPO is hindered; dOPO has polymerization double bonds of methyl methacrylate and long carbon chains of polyethylene glycol acrylate, so that the compatibility of the polyphosphate flame retardant and a polymer substrate is improved, and phase separation is avoided; maleic anhydride grafted silicone oil is connected to the surface of an amino modified gamma-cyclodextrin-modified DOPO inclusion compound, so that the polyphosphate flame retardant has high thermal stability and high compatibility after long-chain alkyl modification; amino groups in the modified gamma-cyclodextrin react with maleic anhydride grafted silicone oil to generate an amido bond cross-linked network, so that the thermal migration of DOPO is reduced together, and the high thermal stability of the polyphosphate flame retardant is improved.
Owner:SHOUGUANG LUYUAN SALINIZATION CO LTD

Composition with effects of protecting liver and resisting oxidation and preparation method thereof

The invention relates to the technical field of pharmaceutical preparations, and discloses a composition with liver protection and antioxidation effects and a preparation method thereof.The composition is prepared from galactosamine modified astragalus membranaceus exosome, schisandra chinensis nanocrystals, liquorice-chitosan nanoparticles, lactobacillus acidophilus freeze-dried powder, beta-(1, 3) / (1, 3, 4-tetramethyl-1, 3-pentanediol monoisobutyrate) sourced from saccharomyces cerevisiae, and beta-(1, 3, 4-tetramethyl-1, 3-pentanediol monoisobutyrate). And (6) a dextran, grape exosome-curcumin hybrid vesicle freeze-dried powder, a curcumin-mitochondrial targeting peptide compound, a resveratrol-hydroxypropyl-beta-cyclodextrin inclusion compound and reduced panthenol. According to the liver-protecting and anti-oxidation composition disclosed by the invention, multi-dimensional intervention on liver protection is realized through an elaborately designed ternary system. The system is composed of a traditional Chinese medicine extract, a microorganism-plant exosome combination and a high-bioavailability antioxidant, all the parts have a synergistic effect, and the liver protection effect is remarkably improved.
Owner:BEIJING FUTAIMING BIOTECHNOLOGY CO LTD

Method for reducing content of aged starch and soluble miscellaneous sugar in alpha-cyclodextrin

PendingCN121087125AFermentationAmylaseSugar
The invention discloses a method for reducing the content of aged starch and soluble miscellaneous sugar in alpha-cyclodextrin, and belongs to the technical field of alpha-cyclodextrin synthesis, the method comprises the following steps: liquefaction, conversion, primary filtration, inclusion, secondary filtration, complexing agent removal and post-treatment; the conversion comprises the following steps: adding alpha-CGTase and isoamylase into the starch liquefied liquid at 38-42 DEG C, adjusting the pH value to 5.30-5.70, and carrying out conversion to obtain a conversion liquid; the primary filtration comprises the following steps: carrying out enzyme deactivation treatment on the conversion liquid, filtering, washing a filter cake with water, and combining the washing liquid with the filtrate to obtain primary filtrate; and the secondary filtration comprises the following steps: filtering the material liquid containing the complex, taking a filter cake, and washing the filter cake with water to obtain the inclusion compound. The preparation method of the alpha-cyclodextrin is improved, so that the alpha-cyclodextrin with high yield and high stability is obtained, and the industrial controllability is realized.
Owner:SHANDONG GUOBANG PHARMA +1

Novel long-acting bird repellent and preparation method thereof

The invention discloses a novel long-acting bird repellent and a preparation method thereof, and belongs to the technical field of chemical bird repelling. The bird repellent is composed of a core material and a wall material, the core material is a mixture of geraniol, cinnamyl aldehyde and allicin according to the mass ratio of 1: (1.2-1.5): (0.5-0.8), the wall material is modified beta-cyclodextrin and pumpkin seed protein nanoparticles, and the mass ratio of the geraniol, the cinnamyl aldehyde and the allicin is (5-7): (3-5): (1-3). The preparation method comprises the following steps: preparing the quaternary ammonium salt modified beta-cyclodextrin, including the core material, performing high-speed shearing emulsification on the quaternary ammonium salt modified beta-cyclodextrin and the pumpkin seed protein nano dispersion liquid, and performing freeze drying to obtain a final product. According to the invention, a stable and compact'molecular inclusion + physical barrier 'dual slow-release structure is constructed by utilizing the electrostatic interaction between the positively charged modified beta-cyclodextrin and the negatively charged protein nanoparticles, the release time of effective components is remarkably prolonged to 9 months or more, and the composite material has excellent rain wash resistance and ultraviolet resistance, and can be used for preparing a composite material with a good application prospect. And efficient, environment-friendly and long-acting bird repelling is realized.
Owner:SHANDONG SHENYE ELECTRIC TECH CO LTD

Dihydroartemisinic acid inclusion compound as well as preparation method and application thereof

The invention relates to a dihydroartemisinic acid inclusion compound as well as a preparation method and application thereof. The dihydroarteannuic acid clathrate compound comprises dihydroarteannuic acid and a cyclodextrin compound wrapping the dihydroarteannuic acid. The cyclodextrin compound comprises cyclodextrin and / or a cyclodextrin derivative. According to the invention, the inclusion effect of the cyclodextrin compound on the dihydroarteannuic acid is utilized, so that dihydroarteannuic acid molecules are embedded in the tubular structure of the cyclodextrin compound, and the water solubility of the dihydroarteannuic acid is greatly improved.
Owner:YUNNAN YUNKE CHARACTERISTIC PLANT EXTRACTION LABORATORY CO LTD +1

Salicylic acid-cyclodextrin-amino acid ternary inclusion compound as well as preparation method and application thereof

ActiveCN120918962ACosmetic preparationsAntibacterial agentsPolymer scienceAmino acid side chain
The invention discloses a salicylic acid-cyclodextrin-amino acid ternary inclusion compound and a preparation method thereof. The salicylic acid-cyclodextrin-amino acid ternary inclusion compound is formed by salicylic acid, amino acid and a cyclodextrin derivative through non-covalent bond interaction, the cyclodextrin derivative is a cross-linked beta-cyclodextrin polymer, salicylic acid molecules are included in a cavity of the cross-linked beta-cyclodextrin polymer, and the cross-linked beta-cyclodextrin polymer is a cross-linked beta-cyclodextrin polymer. And meanwhile, guanidyl or carboxyl of an amino acid side chain interacts with hydroxyl outside the cross-linked beta-cyclodextrin polymer or an exposed part of an included salicylic acid molecule. According to the invention, a cross-linked beta-cyclodextrin polymer is used, arginine is introduced as a synergist, a salicylic acid-cross-linked beta-cyclodextrin polymer-arginine ternary clathrate compound is constructed, and through charge neutralization and hydrogen bond network synergistic effect, clathration efficiency is significantly improved, and water solubility of salicylic acid is improved.
Owner:AIXIMEI (ZHUHAI) BIOTECHNOLOGY CO LTD

Preparation method for reverse osmosis membrane resistant to high-temperature water environment

The invention provides a preparation method for a reverse osmosis membrane resistant to a high-temperature water environment, comprising: synthesizing an α-cyclodextrin@polyethylene glycol supramolecular inclusion complex by a saturated aqueous solution coprecipitation method; preparing an aqueous phase solution containing m-phenylenediamine, D(+) camphorsulfonic acid and triethylamine; preparing an oil phase solution containing trimesoyl chloride; preparing a secondary aqueous solution containing α-cyclodextrin@polyethylene glycol powder and triethylamine; forming an ultrathin polyamide separation layer on a base membrane by interfacial polymerization; and performing secondary interfacial polymerization to form an α-CD@PEG polyester protection layer, and storing a prepared reverse osmosis membrane in ultrapure water.
Owner:ZHEJIANG JINMO ENVIRONMENT TECH CO LTD

Silymarin inclusion compound liposome as well as preparation method and application thereof

The invention relates to the technical field of biology, in particular to silymarin inclusion compound lipidosome and a preparation method and application thereof. The silymarin inclusion compound liposome is prepared from the following components in parts by weight: 10 to 48 parts of silymarin, 10 to 53 parts of phospholipid, 5 to 10 parts of Arabic gum and 25 to 70 parts of cyclodextrin. According to the invention, cyclodextrin and phospholipid are combined to form a double-drug-loading structure; on the basis, Arabic gum is used as a film-forming agent to form a protective film on the surface of the liposome, so that the stability of the system is further improved; the silymarin inclusion compound is encapsulated in a water phase in the liposome, and meanwhile, part of free silymarin is encapsulated in a lipid bilayer. According to the structure, the solubility and the encapsulation efficiency of the silymarin are remarkably improved, the liposome stability is enhanced, the drug release is effectively controlled, and the silymarin inclusion compound lipid is simple in preparation process and suitable for industrial production.
Owner:EFFEPHARM (SHANGHAI) CO LTD

Pterostilbene-based stability enhanced antioxidant as well as preparation method and application thereof

The invention relates to the technical field of functional antioxidants, in particular to a stability-enhanced antioxidant based on pterostilbene and a preparation method and application thereof. The pterostilbene tablet comprises the following components in percentage by weight: 10-30% of pterostilbene, 8-20% of Arabic gum, 5-15% of tocopheryl succinate, 1-5% of disodium ethylene diamine tetraacetate, 30-60% of beta-cyclodextrin, 2-8% of rosmarinic acid, 1-6% of chitosan quaternary ammonium salt, 0.5-3% of nano silicon dioxide and 2-7% of polyglycerol fatty acid ester. In the preparation process, beta-cyclodextrin and pterostilbene form an inclusion compound, the dispersity of nano silicon dioxide and chitosan quaternary ammonium salt is improved through hydrogen bonds, and tea polyphenol or ascorbyl palmitate can be added to enhance the synergistic effect. The antioxidant is high in stability, high in pterostilbene retention rate, uniform in dispersion, free of agglomeration, excellent in antioxidant activity, suitable for the fields of foods, cosmetics and medicines, simple in preparation process, low in consumption and suitable for industrial production.
Owner:WANG SHUHE BIOMEDICINE (WUHAN) CO LTD

A composition for reducing uric acid and a method for preparing the same

ActiveCN120771238BOrganic active ingredientsPowder deliveryAscophyllum nodosum extractPhospholipid complex
The application relates to the technical field of traditional Chinese medicines, in particular to a uric acid reducing composition and a preparation method thereof. The uric acid reducing composition comprises 35-45 parts of a cyclodextrin inclusion compound, 25-35 parts of nano-liposomes, 20-30 parts of a chicory extract-phospholipid complex and 5-8 parts of an antioxidant complex; the preparation method of the cyclodextrin inclusion compound comprises the following steps: step 1, adding beta-cyclodextrin into water, stirring and dissolving, adding pueraria extract, drying after inclusion reaction, and obtaining inclusion compound a; step 2, adding hydroxypropyl-gamma-cyclodextrin into water, stirring, adding mulberry leaf extract, drying after inclusion, and obtaining inclusion compound b; and step 3, mixing the inclusion compound a and the inclusion compound b, and obtaining the product. The uric acid reducing composition can more comprehensively and efficiently reduce blood uric acid level, and has high safety, high stability and high bioavailability. The preparation method is simple, easy to industrialize and beneficial to large-scale industrial production.
Owner:SHANGHAI HQL TECH DEV CO LTD

Salidroside composition with core-shell-shell structure and preparation method and use thereof

The present application provides a rhodiolide composition with a core-shell-shell structure, a preparation method thereof comprising the steps of: 1) EGCG inclusion: adding beta-cyclodextrin and EGCG into water, ultrasonic, forming an inclusion compound; 2) liposome assembly: weighing soybean phospholipid and cholesterol, dissolving in chloroform to form a uniform solution; weighing rhodiolide, dissolving in the uniform solution, rotary evaporation to remove chloroform, then adding the inclusion compound and PBS buffer into the container, hydrating, forming a liposome wrapping rhodiolide and inclusion compound; 3) shell loading: weighing collagen, mixing with chitosan solution uniformly to form a complex; adding the complex into the liposome, the complex is coated on the outer layer of the liposome, centrifugal purification, obtaining a rhodiolide composition with a core-shell-shell structure. The present application belongs to the technical field of cosmetic raw materials, and the rhodiolide composition provided has the advantages of high stability, good transdermal effect, and significant anti-aging effect.
Owner:PEPTIDE SOURCE (GUANGZHOU) BIOTECHNOLOGY CO LTD +1

Covalent organic framework antibacterial material with NO light-controlled release as well as preparation method and application of covalent organic framework antibacterial material

The invention discloses a covalent organic framework antibacterial material with NO light-controlled release as well as a preparation method and application thereof, and belongs to the technical field of biological medicines. The covalent organic framework antibacterial material is a porous polymer taking a cyclodextrin inclusion compound and a porphyrin metal coordination compound as structural units; a plurality of porphyrin metal coordination compounds surround the cyclodextrin inclusion compound in each structural unit, and the porphyrin metal coordination compounds are not on the same plane; the cyclodextrin inclusion compound is obtained by inclusion of BNN6 with beta-cyclodextrin; the porphyrin metal coordination compound is a coordination compound of porphyrin and copper. The preparation method comprises the following steps: firstly preparing a cyclodextrin porphyrin porous polymer, then matching the cyclodextrin porphyrin porous polymer with copper and entrapping BNN6 to obtain a covalent organic framework antibacterial material, utilizing NO release and combining simulated photo-thermal, photodynamic, peroxidase and glutathione peroxidase to achieve synergistic antibacterial effect, and remarkably accelerating the recovery of bacterial infected wounds.
Owner:WEIFANG MEDICAL UNIV

Functional minced garlic sauce based on fermentation engineering and preparation method

The invention belongs to the technical field of functional condiments, and provides a functional minced garlic sauce based on fermentation engineering and a preparation method thereof.According to the functional minced garlic sauce based on fermentation engineering and the preparation method thereof, the design that a lactic acid fermentation minced garlic matrix is combined with a double-layer structure functional microcapsule dispersion phase is adopted, and an inner core layer is composed of a clathrate compound formed by gamma cyclodextrin and allicin; an outer shell is formed by compounding protein and high-methoxyl pectin under a specific pH condition and is subjected to calcium ion cross-linking stabilization, and an immobilized gamma-glutamyltransferase conversion and a lactobacillus plantarum and lactobacillus rhamnosus co-fermentation process are adopted; the microcapsule has the advantages that the content of S-allyl L-cysteine is larger than or equal to 220 mg / kg, the particle size D50 of the microcapsule is 5-10 micrometers, and the viable bacterium stability is good under the low-salt condition, the technical problems that allicin retention and stability of minced garlic seasoning products are insufficient, and functional ingredient enrichment and viable bacterium stability are difficult to consider under the low-salt condition are solved, and the technical effects that the content of S-allyl L-cysteine is larger than or equal to 220 mg / kg and the particle size D50 of the microcapsule is 5-10 micrometers are achieved. And the method has a wide industrial application value.
Owner:SHANDONG YUZHOUXIANG FOOD CO LTD

Salidroside composition with core-shell-shell structure as well as preparation method and application of salidroside composition

The invention provides a salidroside composition with a core-shell-shell structure, and a preparation method of the salidroside composition comprises the following steps: 1) EGCG (epigallocatechin gallate) clathration: adding beta-cyclodextrin and EGCG into water, and carrying out ultrasonic treatment to form a clathrate compound; 2) liposome assembly: weighing soybean phospholipid and cholesterol, and dissolving in chloroform to form a uniform solution; the preparation method comprises the following steps: weighing salidroside, dissolving the salidroside in a uniform solution, carrying out rotary evaporation to remove chloroform, then adding an inclusion compound and a PBS (Phosphate Buffer Solution) into a container, and hydrating to form lipidosome wrapping the salidroside and the inclusion compound; 3) shell loading: weighing collagen, and uniformly mixing the collagen with the chitosan solution to form a compound; the salidroside composition with the core-shell-shell structure is obtained by dropwise adding the compound into the lipidosome, coating the outer layer of the lipidosome with the compound and carrying out centrifugal purification. The invention belongs to the technical field of cosmetic raw materials, and provides a salidroside composition which has the advantages of high stability, good transdermal effect, remarkable anti-aging effect and the like.
Owner:PEPTIDE SOURCE (GUANGZHOU) BIOTECHNOLOGY CO LTD +1

A decontamination composite solution and a preparation method and application of a gel film thereof

This invention discloses a method for preparing a detergency-removing composite solution and its gel membrane, as well as its applications. Based on the host-guest inclusion mechanism of cyclodextrin, its hydrophobic cavity is achieved by "encapsulating" hydrophobic molecules or their hydrophobic portions. The volume of the hydrophobic portion / functional group of the complexing agent molecule is smaller than the volume of the cyclodextrin cavity. The complexing agent forms a complex with cyclodextrin, thus dispersing well in the solution. Furthermore, complexing agents with good coordination ability for radioactive ions can almost always form inclusion complexes with cyclodextrin. The polysaccharide molecular chains used in this invention are rich in hydrophilic functional groups such as hydroxyl and amino groups, giving the gel membrane good hydrophilicity, low ion transport resistance, and short equilibrium time. The hydroxyl and amino functional groups also participate in the coordination process of radioactive ions, further improving the adsorption capacity of the gel membrane. The method and application of this invention have strong universality, can simultaneously remove multiple radioactive ions, and can be used on a large scale.
Owner:CHINA INSTITUTE OF ATOMIC ENERGY

A modified bromhexine hydrochloride inhalation solution with enhanced stability and a method for its preparation

The application discloses a modified bromhexine hydrochloride inhalation solution with enhanced stability and a preparation method thereof, and belongs to the technical field of medical preparations. The inhalation solution is mainly prepared from a targeting impurity control modified bromhexine hydrochloride inclusion compound, a special composite buffer mother liquor for inhibiting impurity B, inhalation grade sodium chloride, pharmaceutical grade sodium hydroxide and water for injection, and the pH value of the finished product is 4.5-5.5. The application constructs a three-stage progressive modification system, covalently grafts a mercapto-activated L-cysteine derivative onto hydroxypropyl-gamma-cyclodextrin to prepare a functional carrier, and realizes molecular-level isolation of bromhexine hydrochloride through host-guest inclusion, thereby blocking the generation of impurity B of bromhexine hydrochloride from the whole path, and solving the core pain points of easy impurity exceeding, short effective period and airway irritation of the existing product. The application can realize long-acting stable storage for 36 months, is suitable for the existing industrial production line, and has high clinical application and industrialization values.
Owner:HEFEI SINOPHARM NOVO PHARM CO LTD

A method for producing a clathrate pharmaceutical

A method for producing an inclusion complex drug includes the following steps: adding cyclodextrin to an aqueous solution of ibuprofen sodium salt at a saturation concentration at a first temperature, then placing it in an electrodialysis apparatus to obtain a first crystallization solution; then removing it and adding acid to adjust the pH to 6.0-6.5, controlling the temperature at a second temperature to obtain a second crystallization solution; placing the second crystallization solution in an electrodialysis apparatus to obtain a third crystallization solution; then removing it and continuing to add acid to adjust the pH to below 3.0 to obtain a fourth crystallization solution; filtering and recovering the fourth crystallization solution, and rinsing to obtain the ibuprofen inclusion complex. This application uses pre-added cyclodextrin, with cyclodextrin and the ibuprofen sodium salt obtained from the reaction as feedstock, then obtaining the second crystallization solution through electrodialysis acidification and acid treatment, followed by electrodialysis to obtain raw materials that can be used as nucleation sites for crystallization, and finally adding acid for final crystallization. The entire crystallization process is controllable.
Owner:SHANDONG XINHUA PHARMA CO LTD

Hydrocolloid acne patch and preparation method thereof

The invention belongs to the technical field of medical dressings, and provides a hydrocolloid acne patch and a preparation method thereof. According to the invention, beta-cyclodextrin functionalized gelatin and adamantane functionalized hyaluronic acid are subjected to inclusion interaction to form a reversible cross-linked network, and hydroxypropyl trimethyl ammonium chloride chitosan and sodium carboxymethyl cellulose are subjected to electrostatic interaction to form a polyelectrolyte cross-linked network; the genipin is combined with a primary amine group amido bond to form a triple cross-linked network structure design of a covalent cross-linked network, and antibacterial components such as a gamma-cyclodextrin-salicylic acid inclusion compound are loaded, so that the excellent properties that the self-healing recovery rate is 90-95%, the water vapor transmission rate is 500-900g. M <-2 >. 24h <-1 >, and the peel strength is greater than or equal to 1.0 N / 25mm are realized; the technical problem that an existing hydrocolloid acne patch is insufficient in antibacterial persistence and self-healing and repairing capacity is solved, and wide application value is achieved.
Owner:JIANGSU HONGSHENG BIOLOGICAL ENG CO LTD

Preparation method for improving quality of surimi product by using V-type starch-grease inclusion compound

The invention discloses a processing method for improving the quality of a surimi product by using a V-type starch-grease inclusion compound. The method comprises the following steps: preparing V-type starch, preparing a V-type starch-grease inclusion compound, blending raw materials, carrying out gradient thermal induction, cooling and shaping, carrying out vacuum exhausting and filling, and sterilizing. The V-type starch-grease inclusion compound is added into the surimi product, and the V-type starch can be embedded into a gel matrix after absorbing water and expanding, so that the flowability of water is effectively limited, the water-holding capacity of the surimi product is further enhanced, and the cooking loss is reduced; and pores in the gel can be physically filled and occupied, so that the gel network structure is more compact, the deformation resistance is improved, and the elasticity and the gel strength of the surimi product are enhanced, thereby optimizing the texture characteristics. The V-type starch-grease inclusion compound also effectively masks characteristic fishy smell substances of the surimi and releases specific flavor components of the starch-grease, so that the surimi product has better flavor characteristics.
Owner:GUANGDONG OCEAN UNIVERSITY

Application of licorcidine and clathrate compound thereof in preparation of malassezia furfur antibacterial agent

The invention provides application of licorcidine and an inclusion compound thereof in preparation of a malassezia furfur antibacterial agent, belongs to the technical field of biological medicines, and discloses a remarkable inhibition effect of licorcidine on malassezia furfur for the first time, and the licorcidine is prepared into the inclusion compound to increase water solubility so as to be further used for inhibiting malassezia furfur. The preparation method of the licorcidine inclusion compound comprises the following steps: dropwise adding a licorcidine solution into a beta-hydroxypropyl cyclodextrin solution, and mixing to obtain a mixed solution; and removing the solvent of the mixed solution, resuspending with water, and removing insoluble substances to obtain the product. The MIC of the glycyrrhizine to the malassezia furfur strain is 25 [mu] g / mL, and the MIC of the glycyrrhizine inclusion compound to the malassezia furfur strain is 12.5 [mu] g / mL; compared with a chemically synthesized antibacterial component, the licorcidine or licorcidine inclusion compound has better biocompatibility and safety, can be used for treating skin diseases caused by malassezia furfur, and has wide application potential.
Owner:BEIJING UNIV OF CHEM TECH +1

Eupatorium fortunei extract slow-release pillow filler with temperature and humidity double responses

The invention discloses a scheme design of a temperature and humidity dual-response eupatorium extract slow-release pillow filler, and belongs to the technical field of functional home textile materials. The problems that an existing eupatorium pillow is single in filler response, fast in effective component loss, poor in signal transmission and insufficient in comfort level are solved. According to the technical scheme, the preparation method comprises the following steps: preparing an eupatorium volatile oil-hydroxypropyl-beta-cyclodextrin inclusion compound (the inclusion rate is 88-92%), and loading the inclusion compound on gradient pore activated ceramic balls (the surface layer is 5-8 [mu] m, the transition layer is 8-10 [mu] m and the core layer is 15-20 [mu] m); coating a composite coating of a beewax-sunflower wax-coconut fat temperature-sensitive matrix (phase change is 32-33 DEG C) and hydroxypropyl methyl cellulose-sodium alginate humidity-sensitive gel (50%-70% RH expansion is 150%-200%); and a three-layer composite bag (3 mm silica gel salient points are arranged on the inner layer) is matched. The 24-hour release rate of the filler during double-signal triggering is 68-72%, the day time is less than or equal to 15%, the service life is 9 months, and the filler is mainly applied to sleep-aiding pillows to improve the sleep quality and comfort.
Owner:SHENZHEN LIUDE TRADING CO LTD

Antibacterial fiber material as well as preparation method and application thereof

The invention belongs to the technical field of antibacterial materials, and discloses an antibacterial fiber material as well as a preparation method and application thereof. The preparation method of the antibacterial fiber material comprises the following steps: heating polyamide and maleic anhydride to react, then adding a composite antibacterial agent, melting, mixing and cooling to obtain an antibacterial-polyamide sheet, and then carrying out melt spinning and drafting treatment to obtain the antibacterial fiber material, the preparation process of the composite antibacterial agent comprises the following steps: (1) mixing cyclodextrin and silver nitrate for reaction to obtain an inclusion compound; (2) mixing cyclodextrin with nano-zinc oxide, and performing ultrasonic dispersion to obtain a nano-zinc oxide coating; and (3) dissolving chitosan in an acetic acid aqueous solution, then adding the inclusion compound, the nano-zinc oxide coating and a catalyst, and reacting to obtain the composite antibacterial agent. The antibacterial fiber material has the characteristic of washing durability, and when the antibacterial fiber material is used for preparing textiles such as clothes and socks, a good antibacterial effect is still kept even if the antibacterial fiber material is washed for multiple times.
Owner:SHENZHEN ZHONGKE RONGHUA TECHNOLOGY CO LTD

Preparation method and application of temperature-sensing hole-cutting liquid surface layer material

The invention relates to the technical field of composite materials, in particular to a preparation method and application of a warm-heat-sensing hole cutting liquid surface layer material. The material comprises a non-woven fabric substrate and a nano non-woven fabric which is sprayed on the non-woven fabric substrate and contains a warming agent clathrate compound and soft components, the material is subjected to hydrophobic after-treatment and fine hole cutting treatment, and the material has warm feeling, softness, water resistance, high fluid absorption efficiency and biodegradability, can be applied to the fields of high-end hygienic products, medical treatment, clothing, air filtration and the like, and is wide in application prospect.
Owner:ZHUYOU (GUANGZHOU) FLUID TECHNOLOGY CO LTD

Long-acting microsphere sustained release preparation and preparation method thereof

The invention provides a long-acting microsphere sustained release preparation and a preparation method thereof, and belongs to the technical field of sustained release preparations, the long-acting microsphere sustained release preparation is prepared from the following raw materials of effective components: 9.5 to 10.5 parts of antipsychotic drug, 48 to 50 parts of hydroxypropyl-beta-cyclodextrin, 50 to 52 parts of polylactic acid-glycolic acid copolymer, 1.25 to 1.3 parts of glycerol triacetate and 10 to 11 parts of polyvinyl alcohol. The preparation method comprises the following steps: firstly, the hydroxypropyl-beta-cyclodextrin is used for clathration of the antipsychotic drug, the obtained clathrate compound is further clathrated by the polylactic acid-glycolic acid copolymer, and the long-acting microsphere sustained release preparation is obtained. According to the invention, the double-valve design of beta-CD and PLGA synergistic inclusion is utilized, so that the preparation can realize two-stage release; the macroscopic slow release characteristic of the PLGA is combined with the microcosmic express characteristic of the hydroxypropyl-beta-cyclodextrin, so that the technical limitation of a single carrier is broken through.
Owner:LVYE JIAAO PHARM SHIJIAZHUANG CO LTD

Photodynamic antibacterial modified atmosphere film as well as preparation method and application thereof

The invention belongs to the technical field of food packaging materials, and discloses a photodynamic antibacterial modified atmosphere film as well as a preparation method and application thereof. The antibacterial modified atmosphere membrane is obtained by drying a membrane casting solution, the membrane casting solution comprises the following components in percentage by mass: 80-95% of anionic waterborne polyurethane emulsion, 5-20% of cationic quaternized nanocellulose and an antibacterial agent inclusion compound which accounts for 1-10% of the total mass of the components, and the antibacterial agent inclusion compound is a curcumin-cyclodextrin inclusion compound. The transparent film which has good compatibility and obviously improved air conditioning performance and mechanical performance is successfully prepared, the film has excellent antioxidant and photodynamic antibacterial functions, and the defect that an existing film is single in function is overcome. When the functional waterborne polyurethane film is applied to strawberry preservation, the oxidation and corruption process of strawberries is effectively delayed, the purpose of prolonging the preservation period is achieved, reliable support is provided for preparation of the functional waterborne polyurethane film and food preservation application, and the functional waterborne polyurethane film has important theoretical and practical significance.
Owner:SOUTH CHINA UNIV OF TECH

Jasmine flower essential oil beta-cyclodextrin inclusion compound and preparation method thereof

The invention relates to the technical field of food beverages, and discloses a jasmine flower essential oil beta-cyclodextrin inclusion compound and a preparation method thereof. The method comprises the following steps: dissolving beta-cyclodextrin in water to obtain a wall material solution; dissolving jasmine flower essential oil in absolute ethyl alcohol to prepare a core material solution; slowly dropwise adding the core material solution into the wall material solution, and stirring to form an emulsion; and performing vacuum freeze drying on the emulsion to obtain the inclusion compound. Furthermore, Tween 60 and other emulsifiers can be added into the core material solution to improve the dispersity, and the quality of the powder is improved through program control of sectional type pre-freezing, main drying and post-drying. The obtained clathrate compound is solid powder, the particle size is 0.7-4.6 microns, the clathrate compound is in an irregular shape, secondary particles are attached to the surfaces of the particles, and the clathrate compound has a certain pore structure. Compared with the prior art, the preparation method has the advantages that the food-grade beta-cyclodextrin is used as a unique wall material, a large number of surfactants and a complex process are avoided, the preparation is simple and convenient, the cost is low, and the obtained product has higher jasmine essential oil embedding rate, aroma retentivity and water solubility.
Owner:HANGZHOU TEA RES INST CHINA COOP

Perianal care solution containing herbaceous plants and hyaluronic acid and preparation method of perianal care solution

The invention discloses a perianal care solution containing herbaceous plants and hyaluronic acid and a preparation method of the perianal care solution, and belongs to the technical field of care solutions, the preparation method comprises the following steps: preparing a decolorizing agent, preparing a composite inclusion compound, extracting and mixing; the preparation method of the composite clathrate compound comprises the following steps: mixing hydroxypropyl-beta-cyclodextrin and pure water, stirring at room temperature until the hydroxypropyl-beta-cyclodextrin and the pure water are completely dissolved, adding ethyl lauroyl arginate hydrochloride, stirring at 55-60 DEG C, adding small molecular hyaluronic acid, stirring at room temperature, refrigerating at-22 DEG C to-18 DEG C, freeze-drying at-80 DEG C to-75 DEG C, and grinding to obtain the composite clathrate compound. The perianal care solution prepared by the invention contains the herbaceous plant extract and the hyaluronic acid, and is good in oxidation resistance, good in care effect, free of precipitation and good in storage resistance.
Owner:SHANDONG FOCUSFREDA BIOTECH CO LTD

Anti-cracking treatment method for peach wood

PendingCN120697138ARadiation/waves wood treatmentWood treatment detailsVegetable oilEmulsion
The invention discloses an anti-cracking treatment method for peach wood, and belongs to the technical field of wood anti-cracking treatment. Comprising the following steps: mixing and stirring a vegetable oil inclusion compound, a plant-derived insect repellant inclusion compound, amino acid, absolute ethyl alcohol and a surfactant compounding agent for reaction to obtain a mixed solution, and mixing and stirring the mixed solution and deionized water to obtain a composite emulsion; after peach wood is soaked in a caustic soda mixed solution, the peach wood is completely soaked in the composite emulsion, and pretreated peach wood is obtained through ultrasonic soaking; and the pretreated peach wood is washed and then soaked in a metal ion solution, and finally anti-cracking treatment is completed through drying. According to the clathration system constructed by the method disclosed by the invention, the anti-cracking treatment of peach wood is realized through the synergistic cooperation of hydrogen bond combination and metal coordination.
Owner:SHANXI LONGXINSHAN CULTURE DEVELOPMENT CO LTD

A water-dispersible 25-hydroxyvitamin D3 powder and a method for preparing the same

The present application provides a kind of water dispersion type 25-hydroxyvitamin D3 Powder inclusion compound, it is characterized in that, including 25-hydroxyvitamin D3, β-cyclodextrin, malt dextrin, wherein, the mass ratio of β-cyclodextrin and 25-hydroxyvitamin D3 is 3-6:1, the mass ratio of malt dextrin and 25-hydroxyvitamin D3 is 10-20:1, in the inclusion compound, β-cyclodextrin, malt dextrin jointly as inclusion compound's inclusion shell, 25-hydroxyvitamin D3 as inclusion compound's content.
Owner:SUZHOU LEAD BIOTECH CO LTD

High-stability theanine soft candy and preparation method thereof

The invention belongs to the technical field of food processing, and particularly relates to high-stability theanine soft sugar and a preparation method thereof. The preparation method comprises the following steps: S1, uniformly mixing theanine and a carboxylate polymer in water, adjusting the temperature to 30-40 DEG C and the pH value to 4-5, carrying out a heat preservation reaction for 25-35 min, and then carrying out vacuum drying, grinding and sieving to obtain a theanine inclusion compound; s2, mixing syrup prepared by heating and dissolving carbohydrates with the gel after swelling and gelatinizing, and boiling to form a sugar solution; and S3, fully mixing the theanine inclusion compound with the sugar solution, controlling the temperature at 65-75 DEG C, adding a metal compound buffer solution, uniformly stirring and mixing, carrying out injection molding, cooling and shaping, and drying to obtain the theanine soft sugar. By means of the collaborative design of inclusion protection and ion collaborative gel strengthening, the activity stability of theanine can be guaranteed, the gel strength and texture of the soft sweets are optimized, and the market competitiveness of products is improved.
Owner:GUANGDONG FUWEI FRUITS & NUTS MFG CO LTD