186 results about "Acid molecule" patented technology

The invention provides a method for modulating gene expression by contacting a cellular system with a double-stranded ribonucleic acid molecule capable of associating with a regulatory machinery that controls transcription of one or more genes, wherein the association results in altered expression of the one or more genes. The invention is further directed to method for directing the differentiation of neuronal stem cells into neurons by contacting a cellular system with a double-stranded ribonucleic acid molecule capable of associating with a regulatory machinery that controls transcription of one or more genes involved in neuronal differentiation and directing the transcription of the one or more genes. In related embodiments, the invention provides particular compositions of double-stranded ribonucleic acid molecules as well as therapeutic and screening applications of the invention.

The invention relates to a method for synthesizing graphene oxide by an ultrasonic assistance Hummers method. The method for synthesizing the graphene oxide includes the steps as follows: firstly adding ultrasonic oscillation in low-temperature and middle-temperature reaction stages of the Hummers method to improve the intercalation efficiency and the oxidation degree of graphite oxide; secondly slowly dropping mixed liquor containing concentrated sulphuric acid into low-temperature deionized water to increase temperature when high-temperature reaction begins, thus effectively preventing intercalated materials such as sulphuric acid molecules and the like from rapidly escaping from graphite layers due to overhigh local temperature; and finally obtaining the graphite oxide through low-speed centrifugation. The method for synthesizing the graphene oxide by using the ultrasonic assistance Hummers method is convenient and fast, saves resources, and can effectively increase spacings of graphite oxide layers. The prepared graphene oxide can serve as a wild phase of a composite material and papyraceous laminated graphite oxide based composite material with high mechanical property and the like can be prepared. The reduction product graphene can be used for preparing graphene-based composite materials such as transparent electrodes, super capacitors, hydrogen storage materials, chemical/ biological sensors, thin film transistors and the like.

Method of deacidizing a gaseous effluent comprising acid compounds such as H₂S, mercaptans, CO₂, COS, SO₂, CS₂. An absorbent solution comprising reactive compounds with at least two amine functions is used and the following stages are carried out: a) contacting the gaseous effluent with a first fraction of the absorbent solution, so as to obtain a gaseous effluent depleted in acid compounds and a liquid effluent laden with acid compounds, b) contacting the liquid effluent obtained in stage a) with a second fraction of absorbent solution laden with molecules more acid than the acid compounds, so as to cause formation of a first liquid phase depleted in acid compounds and of a second liquid phase enriched in acid compounds and laden with more acid molecules, c) separating the first phase from the second phase, d) regenerating the second phase so as to release a gas stream rich in acid compounds and a liquid stream poor in acid compounds and laden with more acid molecules.

The present invention provides compositions, methods, and kits for covalently linking nucleic acid molecules. The methods include a strand invasion step, and the compositions and kits are useful for performing such methods. For example, a method of covalently linking double stranded (ds) nucleic acid molecules can include contacting a first ds nucleic acid molecule, which has a topoisomerase linked to a 3' terminus of one end and has a single stranded 5' overhang at the same end, with a second ds nucleic acid molecule having a blunt end, such that the 5' overhang can hybridize to a complementary sequence of the blunt end of the second nucleic acid molecule, and the topoisomerase can covalently link the ds nucleic acid molecules. The methods are simpler and more efficient than previous methods for covalently linking nucleic acid sequences, and the compositions and kits facilitate practicing the methods, including methods of directionally linking two or more ds nucleic acid molecules.

There is provided a transistor, which includes a deoxyribonucleic acid molecule or a deoxyribonucleic acid molecule aggregate as a part of structural materials, has a source electrode member, a drain electrode member and a gate electrode member, in which at least one of three electrode members connects to the deoxyribonucleic acid molecule or deoxyribonucleic acid molecule aggregate 1

The invention relates to methods for chemically and physically modifying nanotubes with nucleic acid, and uses thereof. In particular, the invention relates to one or more nanotube(s) with one or more numcleic acid molecule(s) with one or more nucleic acid molecule(s) attached thereto.

The invention discloses a soil restoration method based on oxygen activation of iron powder and polyphosphoric acid molecules. According to the method, by utilizing an environment-friendly low-cost oxidation reaction system formed by polyphosphoric acid, zero-valent iron and air, oxygen is activated by a Fe<2+> ligand generated by oxidizing polyphosphoric acid and the iron powder, so that the H2O2 is generated in situ and forms a Fenton reaction with Fe<2+>; and thus pollutants in the organic polluted soil are degraded. Compared with the traditional Fenton system or the similar Fenton system, polyphosphoric acid is very stable, difficult to degrade, environment-friendly and nontoxic to a human body, so that polyphosphoric acid does not generate secondary pollution as compared with other organic ligands, i.e., polyphosphoric acid is more durable in catalytic degradation effect. In addition, as the method is used, the erecting of a complicated device is not required; the restoration process is easy to operate; and the reaction can be performed by only mixing catalysts. Therefore, the dangerousness is avoided, i.e., the employing of a professional operator to perform the operation is not required.

The present invention relates to unique small ribonucleic acid molecules, for example siRNAs and miRNAs, identified and isolated using MPSS. Specifically, the invention is directed to the identification of a library of unique small RNA sequences from Arabidopsis thaliana. In another aspect, the small RNA sequences themselves are useful for performing biological functions, such as for example, RNA interference.

The invention discloses a surface modification process for improving luminance and dispersity of porous silicon. By adopting a method that chemical corrosion is combined with electrochemical corrosion, porous silicon of tidy pore structures can be prepared in a large area, subsequently the porous silicon is subjected to surface modification by using olefin and olefine acid, and Si-C bonds are introduced into the surfaces of silicon grains. The photoluminescence intensity of grains of the modified porous silicon is remarkably improved when being compared with that of the grains of porous silicon which is not subjected to surface modification; and meanwhile the luminance stability of the silicon grains in polar and non-polar solvents is greatly improved, and the phenomenon that the luminous intensity is attenuated along with the time extension is effectively reduced; and in addition, the dispersing property of the silicon grains wrapping olefine acid molecules in polar solvents is good. The surface modification process is simple, convenient to operate and applicable to production in a large scale, and has a good industrial application prospect.

The invention discloses a polyacid-based metal organic frame proton conductor material of inorganic acid molecule functionalization. Polyanions and crystal water molecules are domain-limited in pore canals of the metal organic frame, wherein the structure thereof is HAaPOM-MOF, wherein HA is one of H2SO4 or H3PO4; and POM-MOF is the polyacid-based metal organic frame, and is one of [Ag8L5](PMo12O40)(H2O)10 or [Ag8L5](PW12O40)(H2O)13, wherein L is 5-phenyl tetrazole. The invention further discloses a preparation method for the polyacid-based metal organic frame proton conductor material of the inorganic acid molecule functionalization. The preparation method comprises the following steps: firstly preparing the polyacid-based metal organic frame, uniformly mixing the prepared polyacid-based metal organic frame and HA solution, separating the material, washing, drying to obtain the polyacid-based metal organic frame proton conductor material of the inorganic acid molecule functionalization.

A sterilization germ killing comfort mask, including mask layers held in the mask with a fixed belt. There is a sterilization filter layer, an electrostatic layer, a far-infrared superfine calcium layer, and a facial protection layer from outside to inside of mask body. In use, the outside air passes through a first sterilization filter layer, the preliminary filtration sterilization filter layer removes larger grains of dust and sterilization, electrostatic layer can filter through the sterilization of dust. Superfine calcium far-infrared layer removes acidic dust, bacteria and oily molecular adsorption, and neutralize the acid molecules, sterilization and decomposition of oily molecules absorbed. Facial protection layer strengthen filtering and protection of facial skin. This mask for the various molecules in air dust filtration and sterilization, sterilization dust removal ability, remove the inclusion of peculiar smell in the air at the same time, guarantee the quality of air that users breathe, and the user to wear comfortable, strong practicability.

The invention relates to a method for preparing a slump loss-resistant type polycarboxylic acid water reducer by silanizing a terminal group of amino polyether. The method provided by the invention takes an amino polyether type compound, a silane coupling agent, an unsaturated carboxylic acid type monomer and the like as main reaction raw materials and a polycarboxylic acid water reducer is prepared through firstly hydrolyzing, substituting, then carrying out condensation, and finally copolymerizing; the method comprises the following steps: firstly hydrolyzing by a halogenated silane coupling agent; then taking the silane coupling agent and the amino polyether type compound to be subjected to substitution reaction; carrying out the condensation on a substituted product and a vinyl silane coupling agent hydrolyzed product; taking a condensed product and unsaturated polyoxyethylene ether, a molecular weight regulator and the unsaturated carboxylic acid type monomer to be subjected to free-radical copolymerization reaction under the action of an initiator to prepare the polycarboxylic acid water reducer with a plurality of branched silane modified polyether side chains. The method provided by the invention has the advantages of simple and easy-to-control process, low cost, energy saving and high efficiency, environmental protection and no pollution; dual modification of the side chains of a main chain of a polycarboxylic acid molecule is successfully realized and more excellent water reduction and slump loss resistance performance, which is better than that of a common polycarboxylic acid water reducer, is represented.

The invention provides a method for preparing a magnesium-lithium alloy surface micro-arc oxidation self-assembling super hydrophobic composite coating. The method includes: placing magnesium-lithium alloy in a stainless steel electrolytic cell, and using the magnesium-lithium alloy as anode and the stainless steel electrolytic cell as cathode, treating in a constant-current micro-arc oxidation mode for 5-10 minutes to form a micro-arc oxidation film of the magnesium-lithium alloy; and soaking the treated magnesium-lithium alloy in self-assembling solution for 6-72 hours to build the super hydrophobic composite coating. A self-assembling method is used for assembling amphiphilic organic phosphonic acid molecules on the surface of the micro-oxidation film so as to form a compact and sequential organic molecule layer and the super hydrophobic composite coating on the surface of the magnesium-lithium alloy. By the super hydrophobic composite coating, surface corrosion resistance of the magnesium-lithium alloy is improved greatly while excellent performance of the micro-arc oxidation film is kept.

The invention discloses a mixed type acidity regulator for feed additives. The mixed type acidity regulator is characterized by being prepared from the following components in parts by weight: 25-35 parts of formic acid, 15-25 parts of ammonia water, 8-15 parts of lactic acid, 5-8 parts of acetic acid, 3-5 parts of citric acid and 28-35 parts of silicon dioxide. According to the mixed type acidity regulator disclosed by the invention, firstly various acid components are added into a reaction kettle for sufficient reaction and fusion, and the fused acid components are shifted into an ion state and enter a high uniform state. The mixed type acidity regulator for the feed additives, produced in a manner, has extremely high mixing uniformity, and various acid molecules are highly dispersed, so that the situation that effective components uniformly enter feeds and then the feeds are eaten is facilitated, the situation that animals stably and uniformly digest the feeds is guaranteed, increase of culturing benefits is facilitated, and the mixed type acidity regulator is a development direction of future acidity regulators and other additives. In addition, the liquid acidifying agent disclosed by the invention is safe to use, free from toxic and side effects on the growth of the animals, free from residues, and low in corrosion to animals, human bodies and production equipment.

The invention provides a polyacid-based metal organic framework crystal material and a preparation method thereof and relates to a polyacid-based metal organic framework crystal material with nano porous channels. The invention aims at solving the problems that the polyacid-based metal organic framework material synthesized by adopting the prior art generally has a single porous channel, the finally obtained material does not have the porous channels after a polyacid molecule is immobilized, and therefore, the catalytic activity of the material is low. A chemical formula of the designed and developed flexible ligand assembled polyacid-based metal organic framework material with the nano porous channels is {[CuI(btpe)2][CuII2(H2O)2(btpe)2][BW12]40}}.2H2O. The preparation method comprises the following steps: dissolving borotungstic acid, copper acetate and 1,5-bis(triazole)-pentane into deionized water, regulating pH value, and then carrying out reaction for 3 days at the temperature of160 DEG C. By carrying out the preparation method provided by the invention, the flexible ligand assembled polyacid-based metal organic framework crystal material with the nano porous channels can beobtained.

The present invention is related to novel oral compositions comprising an irreversible gastric H⁺/K⁺-ATPase proton pump inhibitor (PPI) as a gastric acid secretion inhibitor and one or more aliphatic carboxylic acid derivative molecules which activate parietal cells, wherein the derivatives possess delayed or sustained enhancement effect on the PPI activity compared to the non-derivatized acid molecules. The present invention further relates to a method of using such compositions to reduce gastric acid secretion in a mammal.

The invention discloses a method for preparing graphene under the conditions of normal pressure and low temperature, which comprises the following steps that: firstly, volatile acid is used for treating graphite oxide so that volatile acid molecules are adsorbed between sheet layers of the graphite oxide, acidized graphite oxide is obtained, then, a heat treatment expansion method is adopted for preparing the graphene, experiments prove that the acidized graphite oxide generates a large amount of acid gas in the heat expansion process, and the peeling of the graphite oxide is prompted, so thegraphite oxide can generate the expansion peeling in the normal-pressure and low-temperature atmosphere, the graphene can be obtained, and in addition, the obtained graphene has high specific surfacearea. Therefore, the preparation method provided by the invention is simple, is easy to implement and overcomes the defect of vacuum or low-pressure condition limitation required during the graphene preparation in the prior art, the assurance is provided for the large-scale production of the graphene, and wide market application prospects are realized.

The invention belongs to the field of a nanomaterial, and particularly relates to a Dy-containing nano lamellar structure complex photocatalyst and a preparation method thereof. A chemical formula of a Dy-containing nano lamellar structure complex is [DyCu(pdc)2(OAc)2(H2O)2].11H2O; in the formula, pdc is a pyridine carboxylic acid molecule; and the complex is a monoclinic system, a P21/n point group and a complicated 3D structure, and is composed of repeated [DyCu(pdc)2(OAc)2(H2O)2].11H2O units. Cell parameters are as follows: a is equal to 1.3788(4)nm, alpha is equal to 90 degrees, b is equal to 1.1031(3)nm, beta is equal to 100.300(3) degrees, c is equal to 19.978(5)nm, gamma is equal to 90 degrees, V is equal to 2974.63nm<3>, and Z is equal to 4. In the complex, Cu<2+> ions are penta-coordinated, Dy<3+> ions are nona-coordinated, and a three-dimensional network structure is formed. The complex is of relatively uniform lamellar structure and has a photocatalysis effect.