145 results about "Thiophosphoric acid" patented technology

Disclosed is a method for removing heavy metal ions from a phosphoric acid containing stream, the method may include: adding a diluted solution of a dialkyldithiophosphate compound having an alkyl chain length ranging from 8 to 12 carbon atoms to the phosphoric acid containing stream to form a heavy metal ion complex; and separating the heavy metal ion complexes from the phosphoric acid containing stream.

The invention discloses an epoxy resin-based fireproof heat-insulating coating as well as a preparation method and application thereof, and relates to the technical field of fireproof coatings. The epoxy resin-based fireproof heat-insulating coating prepared by the invention comprises an epoxy resin base material and modified ammonium polyphosphate, the epoxy resin base material is prepared by reacting epoxy resin with a hyperbranched block copolymer; hydroxyl hyperbranched polyethylene is used as an initiator and is subjected to chain extension with dihydroxyl-terminated poly (p-dioxanone) under the action of organic alkali, and thiophosphate triphenyl isocyanate is introduced, so that a hyperbranched block copolymer and epoxy resin form a stable cross-linked structure, the flame retardant property is improved, the thermal stability is ensured, and the flame retardant property is improved. The modified ammonium polyphosphate is prepared by coating the surface of ammonium polyphosphate with polyaldehyde polyester and polyamino polyether, so that the flame retardance and adhesive force of the coating are further improved.

The present invention relates to 5′-morpholino amidite monomers as 5′-CE / 5′-tBu phosphoramidite morpholino monomers (2) and process chemistry for the efficient synthesis of N-Trityl or monomethoxytrityl (MMTr)-protected 5′-morpholino amidite monomers and their use in the synthesis of phosphorodiamidate morpholino oligonucleotides (PMO), thiophosphoramidate morpholino oligonucleotides (TMO) and their chimeras which can be used for antisense technology or in general oligonucleotides related research.

The present application belongs to the technical field of phosphoric acid purification, and particularly relates to a heavy metal cadmium removal agent and a removal method for phosphoric acid. The removal agent comprises a solvent and a thiophosphoric acid type capturing agent A and a thiophosphoric acid type capturing agent B dispersed in the solvent; the thiophosphoric acid type capturing agent A and the thiophosphoric acid type capturing agent B are different types of thiophosphoric acid type capturing agents, the thiophosphoric acid type capturing agent A and the thiophosphoric acid type capturing agent B are independently selected from one of a hydrocarbyl dithiophosphoric acid or a salt thereof, a phenolic dithiophosphoric acid or a salt thereof, and an amine dithiophosphoric acid or a salt thereof, and at least one hydrocarbyl dithiophosphoric acid or a salt thereof is selected; the salt is a sodium salt or an ammonium salt; and the solvent is water or an alkaline aqueous solution. The present application uses a combination of dithiophosphoric acid type capturing agents as a cadmium removal agent for wet-process phosphoric acid, and generates a precipitate that is difficult to dissolve in a strong acidic aqueous phase after reaction, so that the cadmium in the phosphoric acid is removed after filtration. Compared with the conventional sulfide precipitation method, the present application has less cadmium residue and less pollution in the phosphoric acid.

The invention provides a gas engine lubricating oil composition and a preparation method thereof. The gas engine lubricating oil composition of the present invention comprises: (A) an alkyl phosphate compound; (B) alkylated diphenylamine; (C) a polyisobutylene succinic acid pentaerythritol ester dispersing agent; (D) a salicylate and / or sulfonate; (E) zinc dialkyl dithiophosphate; (F) an oil-soluble organic molybdenum friction modifier; (G) a metal corrosion inhibitor; (H) a pour point depressant; (I) a major amount of a lubricating base oil. The gas engine lubricating oil composition disclosed by the invention has excellent high-temperature oxidation resistance, cleaning performance, extreme pressure anti-wear performance and anti-corrosion performance.

The embodiment of the specification provides a modification identification method of a thio-phosphorylated nucleic acid sequence, which comprises: performing enzymolysis on a to-be-identified nucleic acid sequence by using a nucleic acid mixed enzyme to obtain an enzymolysis product; performing secondary mass spectrum analysis on the enzymolysis product based on first mass spectrum information; and determining whether a target sequence fragment exists in the to-be-identified nucleic acid sequence based on the first mass spectrum information and the second mass spectrum information. At least the to-be-identified nucleic acid sequence modified by thio-phosphorylation is actually obtained based on a preset modification rule. The first mass spectrum information comprises a theoretical analysis result generated by analyzing a theoretical sequence fragment, and the theoretical sequence fragment is determined based on the preset modification rule, the to-be-identified nucleic acid sequence and the nucleic acid mixed enzyme. The modification identification method can accurately and efficiently identify the chemical modification of the thio-phosphorylated nucleic acid sequence.

The invention discloses a generalized pustular psoriasis diagnosis marker based on metabonomics and application of the generalized pustular psoriasis diagnosis marker. The diagnostic marker is prepared from one or more of the following 35 compounds: pyruvic acid, alpha-ketoisovaleric acid, 2-hydroxybutyric acid, 3-hydroxybutyric acid, methane thiophosphoric acid, proline, uracil, tranexamic acid, 4-aminobutyric acid, threonine, scopoletin, dodecanol, N-methyl-L-leucine, L-cysteine-glycine and L-kynurenine. The feed additive is prepared from the following raw materials: 3-hydroxybenzoic acid, allantoin, delta-tocopherol, xylofuranose, glucose-1-phosphoric acid, pyrophosphate, taurine, L-asparagine, phthalic acid, 4-(dimethylamino) azobenzene, 5-tert-butyl-1h-indole-2, 3-dione, quinic acid, glucose, histidine, lysine, palmitic acid, 7-methylguanine, oleic acid and whale acid. The marker can be used for accurately distinguishing patients with generalized pustular psoriasis from healthy people.

This invention belongs to the field of mineral flotation technology, and discloses a flotation collector for non-ferrous metal sulfide ores, its preparation method, and its application. The collector uses O,O-dialkyldithiophosphate as a starting material, and reacts sequentially with a halocarboxylic acid ester, hydrazine hydrate, potassium hydroxide, and carbon disulfide in anhydrous ethanol in a three-step reaction to obtain the target product, O,O-dialkyldithiophosphate hydrazide-N′-dithiocarbamate potassium. Its molecular structure simultaneously contains three active groups: a dithiophosphate group, an hydrazide group, and a dithiocarbamate group. This invention achieves efficient process connection and smooth transition by optimizing the material ratio, temperature, and time of each reaction step, and has advantages such as mild reaction conditions, simple operation, few side reactions, high yield, and stable product. The prepared collector exhibits excellent collecting performance and good selectivity for non-ferrous metal sulfide ores such as chalcopyrite, and is suitable for widespread application in sulfide ore flotation processes.

The invention relates to the technical field of biological medicines, and particularly discloses synthesis and application of oligonucleotide with a spacer group embedded between 5-terminal oxygen and thiophosphoric acid. The chemical modification strategy comprises the following steps: preparing a modified nucleotide phosphoramidite monomer in which a spacer group is embedded between O5'and thiophosphoric acid P (V); performing solid-phase synthesis on the modified nucleotide phosphoramidite monomer to construct a target oligonucleotide molecule; a spacer group is embedded between oxygen at the 5 '-terminal of the oligonucleotide and thiophosphoric acid P (V) to form a 5'-terminal thiophosphoric acid structure; as the terminal modified thiophosphoric acid belongs to a non-phosphatase substrate, the terminal modified thiophosphoric acid can resist exonuclease degradation and improve the biological activity of siRNA after being modified.

The invention relates to the field of lubrication of ball screws, in particular to long-life creep-resistant lubricating grease for a high-precision ball screw, which comprises the following components in parts by weight: 65 parts of polyolefin, 5-10 parts of pentaerythritol ester, 5-10 parts of isocyanate, 2-5 parts of amine chain extender, 5 parts of PTFE (polytetrafluoroethylene), 1.0-1.5 parts of diphenylamine, 0.1-0.5 part of 2, 4-diphenyl-1, 3-pentanediol monoisobutyrate, 0.1-0.5 part of antioxidant, 0.1-0.5 part of antioxidant and 0.1-0.5 part of lubricant. The composite material is prepared from the following components in parts by weight: 0.5 to 1 part of 2, 6-butylated hydroxytoluene, 1.5 to 2 parts of molybdenum isocaprylate, 0.5 to 1 part of molybdenum bis (2-ethylhexyl) dithiocarbamate, 1 to 2 parts of zinc dialkyl dithiophosphate, 3 parts of calcium petroleum sulfonate, 1 to 1.5 parts of polyisobutene, 0.2 to 0.5 part of benzotriazole and 0.1 to 0.3 part of polymethacrylate. The isocyanate comprises HDI and IPDI, and the amine chain extender comprises TETA and TEPA. According to the invention, isocyanate and the amine chain extender react to form a polyurea macromolecular chain, and a high-energy hydrogen bond network is formed, so that the lubricating grease has relatively high creep resistance; the anti-creep performance is further enhanced through cooperation with the PTFE particles; meanwhile, through cooperation with diphenylamine, the oxidation resistance is promoted, the consumption is reduced, and the service life of the lubricating grease is longer.

The invention relates to the field of lubricating oil, in particular to a compressor oil composition which is prepared from the following components in parts by weight: 0.005 to 0.2 part of an anti-rust agent, 0.05 to 1 part of an extreme pressure anti-wear agent, 0.01 to 0.5 part of a friction reducing agent, 3 to 8 parts of synthetic ester, 0.01 to 1 part of an antioxidant, 0.001 to 0.1 part of an anti-foaming agent and 90 to 97 parts of base oil. The anti-friction agent is a trimethylolpropane-triacid ester derivative, the anti-rust agent is formed by mixing an alkenyl succinic acid half-ester derivative and a carboxyl imidazoline derivative, and the anti-wear reagent at extreme pressure is formed by mixing triphenyl phosphate and an alkyl thiophosphate derivative. The antioxidant is formed by mixing any two of alkyl diphenylamine, alkyl phenyl-alpha-naphthylamine and alkyl hindered phenol. The invention further relates to a preparation method of the compressor oil composition. The compressor oil composition provided by the invention has excellent washing resistance and rust resistance.

This invention proposes a composite foaming agent, a foam drilling fluid, its preparation method, and its application. The composite foaming agent of this invention comprises a first foaming agent of zinc dialkyl thiophosphate (ZDDP) and a second foaming agent of alkyl sulfate, and water. The foam drilling fluid of this invention contains 0.3wt% to 0.8wt% composite foaming agent, 0.2wt% to 0.5wt% foam stabilizer, 1.5wt% to 3.0wt% filtration loss reducer, and the balance being water. The foam drilling fluid has a foam half-life of up to 240 min, a temperature resistance of up to 150℃, and an API filtration loss of ≤12 mL, which is significantly higher than the performance of foam drilling fluids prepared with conventional foaming agents.

The application relates to a method for producing polarized smerons by regulating copper indium thiophosphate through an electric field and application thereof, and the method comprises the following steps: preparing copper indium thiophosphate by a chemical vapor transport method, the molecular formula of the copper indium thiophosphate is Cu 1‑ x InP2S6, 0.28 > x >= 0.15, and the copper indium thiophosphate has ferroelectric domains; the copper indinium thiophosphate is prepared into a nanometer film through a mechanical stripping technology; the nanometer film is placed on the surface of a substrate through a dry transfer technology; a piezoelectric response force microscope technology is used, a voltage is applied on the surface of the nanometer film through a needle tip to form an electric field, the ferroelectric domains are converted into polarized smerons, the direction of the electric field is perpendicular to the nanometer film, and the nanometer film points to the needle tip, and the intensity is 20V / mu.m-40V / mu.m. The method can effectively regulate the conversion of the ferroelectric domains into the polarized smerons without affecting the crystal lattice structure and the morphology of the copper indium thiophosphate.

The application belongs to the technical field of cutting oil, and specifically provides a kind of composite cutting oil and a preparation method thereof.A kind of composite cutting oil uses coconut oil, mineral oil, poly-alpha olefin as mixed base oil, adds specific amount of rust preventive, polyethylene glycol, nano molybdenum disulfide, antioxidant, dispersant and composite additive obtained by chemical combination of carboxylated multi-walled carbon nanotube surface and thiophosphate amine salt, etc., through the synergistic effect of multiple components, the prepared cutting oil has excellent lubricity, extreme pressure and wear resistance, and is suitable for severe extreme pressure cutting environment.

A process for removing impurity metal ions from an acidic metal sulfate containing stream by adding an effective amount of a reagent, comprising at least one dialkyldithiophosphate compound with the alkyl chain length of C1 to C8 to the acidic metal sulfate containing stream to form impurity metal ion complexes; and separating the impurity metal ion complexes from the acidic metal sulfate stream.

The invention discloses a zinc thiophosphate material with a yolk double-shell structure as well as a preparation method and application thereof, and relates to the technical field of sodium ion batteries. The preparation method comprises the following steps: firstly, preparing a ZIF-8 precursor template through a zinc source and solvothermal reaction of 2-methylimidazole, and then sequentially carrying out coating, template etching, synchronous carbonization and vulcanization treatment and phosphorus vulcanization treatment on the ZIF-8 precursor template to finally obtain the ZnPS3 / NC-C material with the yolk double-shell structure and excellent electrochemical performance. Compared with a traditional transition metal thiophosphate preparation process, the method is safer in process, and the yolk double-shell morphology of the metal phosphorus sulfide can be accurately regulated and controlled. Compared with pure zinc thiophosphate prepared by a traditional process, the prepared ZnPS3 / NC-C material with the yolk double-shell structure has the characteristics of hollow and porous characteristics, high specific surface area and structural stability, and shows relatively high first charge-discharge efficiency and excellent cycle stability when being used as a sodium-ion battery negative electrode material.

A working oil composition for shock absorbers, which contains the following components (A) and (B): (A) an ester base oil having a pour point of-45 DEG C or less and a 10% distillation temperature of 300 DEG C or more as determined by the gas chromatography distillation test method specified in JIS K 2254: 1998; and (B) zinc dialkyl dithiophosphate.

The invention discloses a generalized pustular psoriasis diagnosis marker based on metabonomics and application of the generalized pustular psoriasis diagnosis marker. The diagnostic marker is prepared from one or more of the following 35 compounds: pyruvic acid, alpha-ketoisovaleric acid, 2-hydroxybutyric acid, 3-hydroxybutyric acid, methane thiophosphoric acid, proline, uracil, tranexamic acid, 4-aminobutyric acid, threonine, scopoletin, dodecanol, N-methyl-L-leucine, L-cysteine-glycine and L-kynurenine. The feed additive is prepared from the following raw materials: 3-hydroxybenzoic acid, allantoin, delta-tocopherol, xylofuranose, glucose-1-phosphoric acid, pyrophosphate, taurine, L-asparagine, phthalic acid, 4-(dimethylamino) azobenzene, 5-tert-butyl-1h-indole-2, 3-dione, quinic acid, glucose, histidine, lysine, palmitic acid, 7-methylguanine, oleic acid and whale acid. The marker can be used for accurately distinguishing patients with generalized pustular psoriasis from healthy people.

The invention provides a recyclable metal pickling corrosion accelerant and application thereof, and belongs to the technical field of metal corrosion. The O, O '-di (n-propyl) diethylammonium dithiophosphate can be combined with different inorganic acids, has different corrosion effects on low-carbon steel after being combined, can generate different use effects inevitably after being reasonably mixed with different inorganic acids, and can be suitable for scenes with different corrosion requirements. Experiments show that when the O, O '-di (n-propyl) diethylammonium dithiophosphate is combined with hydrochloric acid, the corrosion promotion rate of the O, O'-di (n-propyl) diethylammonium dithiophosphate to low-carbon steel is maximum and can reach 758.42%; and when only the type of the inorganic acid is changed, the corrosion promotion effect on the low-carbon steel is the best after the inorganic acid is combined with sulfuric acid.

The invention belongs to the technical field of protective agents, and particularly relates to a protective agent for a turbocharged engine and a preparation method of the protective agent. The protective agent for the turbocharged engine comprises the following raw materials in parts by mass: 85-90 parts of base oil, 5-8 parts of graphite powder, 0.5-2 parts of oxymolybdenum dialkyldithiophosphate, 3-5 parts of an auxiliary agent, 4-6 parts of a dispersing agent, 1-2 parts of an antioxidant and 2-4 parts of a thickening agent. According to the protective agent for the turbocharged engine, the maximum non-seizure load and the maximum sintering load of engine lubricating oil can be improved, meanwhile, the abrasion resistance is improved, and meanwhile, the stability is high.

The invention discloses a graphene composite lubricating additive as well as a preparation method and application thereof, and belongs to the technical field of lubricating additive preparation. Modified graphene, nano molybdenum disulfide, a dispersing agent and thiophosphate amine salt are mixed and react to obtain the graphene composite lubricating additive. According to the invention, a triple synergistic stabilization mechanism of chemical anchoring, physical blocking and steric hindrance is utilized, so that the compatibility of graphene and base oil is improved, and the dispersion stability of the graphene composite lubricating additive is improved. Meanwhile, the prepared graphene composite lubricating additive can reduce the temperature of a friction pair, can form a friction reaction film containing C, Mo, P and O elements on the surface of the friction pair, reduces friction wear, shows good friction reduction and wear resistance, provides a theoretical basis and technical support for development of high-performance lubricating oil additives and application of high-temperature working conditions, and has wide application prospects. And the high-temperature lubrication problem of the marine diesel engine is solved, and remarkable engineering value and application prospects are achieved.

The invention belongs to the technical field of flotation reagents, and discloses a use method for activating minerals by utilizing ion waste liquid generated by preparing alkyl thiophosphate. The method comprises the following steps: removing or reducing impurities in the waste liquid to obtain purified waste liquid which can be used as an activating agent; and then, in the flotation operation, ore to be treated is crushed, ground and pulped, an inhibitor, the activating agent, a collecting agent and a foaming agent are sequentially added, and target concentrate is obtained after stirring, air inflation and flotation. The activation potential of the alkyl thiophosphate waste liquid on minerals is found for the first time, industrial wastewater is converted into the efficient flotation activating agent, and a traditional activating agent can be replaced and strengthened. According to the method, the pollution problem of the alkyl thiophosphate waste liquid is solved, the flotation reagent cost is reduced, meanwhile, the concentrate grade and the recovery rate of valuable minerals such as zinc ore, gold ore, copper ore and pyrite can be improved, the requirement for green mine construction is met, and a new path is provided for efficient separation of low-grade ore.

A novel bis-ligand chalcopyrite collector and a preparation method and application thereof. The collector is prepared by first synthesizing an intermediate oxalyl diisothiocyanate from oxalyl chloride and thiocyanate, and then reacting the intermediate with an amine or an alcohol using a one-pot method. The collector provided by the present disclosure can form more stable dual-site adsorption on the chalcopyrite surface, thereby generating a more stable double-chelate-ring structure than the single-site adsorption of a traditional chalcopyrite collector such as xanthate and dithiophosphate. The collector not only has higher collection ability and excellent selectivity, but also can achieve efficient copper-sulfur separation even under a low-alkalinity condition. The preparation process of the collector is simple and operable, facilitating the flotation of chalcopyrite and its separation from pyrite.

A lubricating oil composition is disclosed. The composition comprises a major amount of an oil of lubricating viscosity; one or more ashless dispersants; at least one phosphorus-containing antiwear additive, wherein the at least one phosphorus-containing antiwear additive is a phosphorus-containing acid, a phosphate ester, a phosphite ester, a thiophosphate ester, or an amine salt thereof; at least one friction modifier, wherein the at least one friction modifier is a diol, an ethoxylated amine, a fatty acid ester, or an alcohol; a nitrogen-containing friction modifier having the structure wherein R1 and R2 are independently a branched C10-C25 hydrocarbyl group.

The lubricant composition may provide corrosion resistance, oxidation resistance, and reduced wear to the hydraulic system. A lubricant composition can include an ashless dithiophosphate ester in an amount sufficient to provide the lubricant composition with a phosphorus concentration in the range of from 10 ppm to 250 ppm, a metal dialkyldithiophosphate salt, such as zinc dialkyldithiophosphate (ZDDP), in an amount sufficient to provide the lubricant composition with a phosphorus concentration in the range of from 50 ppm to 1000 ppm, a corrosion inhibitor comprising an alkyl triazole derivative in an amount sufficient to provide the lubricant composition with a nitrogen concentration in the range of from 0.75 ppm to 100 ppm; and a major amount of a base oil.

Lubricant compositions may provide corrosion resistance, oxidation resistance, and reduced wear for hydraulic systems. A lubricant composition may comprise an ashless dithiophosphate in an amount sufficient to provide a concentration of phosphorus ranging from 10 ppm to 250 ppm to the lubricant composition, a metal dialkyl dithiophosphate such as zinc dialkyl dithiophosphate (ZDDP) in an amount sufficient to provide a concentration of phosphorus ranging from 50 ppm to 1000 ppm to the lubricant composition, a corrosion inhibitor comprising an alkyltriazole derivative in an amount sufficient to provide a concentration of nitrogen ranging from 0.75 ppm to 100 ppm to the lubricant composition, and a major amount of a base oil.

Provided is the use of two-dimensional nanomaterials in the inhibition of a coronavirus, and specifically disclosed is the use of the two-dimensional nanomaterials in the preparation of a medicament for treating or preventing diseases caused by a coronavirus or of a material for adhering to or inhibiting the coronavirus. The two-dimensional nanomaterial is selected from the group consisting of copper indium thiophosphate (CIPS) nanosheet, graphene oxide nanosheet, molybdenum disulfide nanosheet, black phosphorus nanosheet and mixtures thereof. The coronavirus is selected from one of HCoV-229E, HCoV-OC43, HCoV-NL63, HCoV-HKU1, SARS-CoV, SARS-CoV2 or MERS-CoV. The diseases caused by the coronavirus are diseases caused by coronavirus infection. The material has the advantages of being simple to prepare, having a high biological safety and an excellent effect.

The application belongs to the technical field of organic synthesis, and particularly relates to a kind of beta-carbonyl dithiophosphoric acid ester compounds, preparation method and application. The application is prepared by using cheap and easily available styrene, P4S 10 And alcohol as raw material, tetrabutylammonium tetrafluoroborate ( n Bu4NBF4) as electrolyte, acetonitrile (CH3CN) as solvent, beta-carbonyl dithiophosphoric acid ester compound is prepared in room temperature and air atmosphere. Compared with the preparation method reported previously, the application has the advantages of green, environmental protection, safety, high efficiency and energy saving, the raw material is easy to obtain, and the operation is simple, and has potential industrial application prospect.

The invention discloses a generalized pustular psoriasis diagnosis marker based on metabonomics and application of the generalized pustular psoriasis diagnosis marker. The diagnostic marker is prepared from one or more of the following 35 compounds: pyruvic acid, alpha-ketoisovaleric acid, 2-hydroxybutyric acid, 3-hydroxybutyric acid, methane thiophosphoric acid, proline, uracil, tranexamic acid, 4-aminobutyric acid, threonine, scopoletin, dodecanol, N-methyl-L-leucine, L-cysteine-glycine and L-kynurenine. The feed additive is prepared from the following raw materials: 3-hydroxybenzoic acid, allantoin, delta-tocopherol, xylofuranose, glucose-1-phosphoric acid, pyrophosphate, taurine, L-asparagine, phthalic acid, 4-(dimethylamino) azobenzene, 5-tert-butyl-1h-indole-2, 3-dione, quinic acid, glucose, histidine, lysine, palmitic acid, 7-methylguanine, oleic acid and whale acid. The marker can be used for accurately distinguishing patients with generalized pustular psoriasis from healthy people.

This invention belongs to the field of biomedicine, specifically relating to the development and application of oligonucleotide drugs targeting the key assembly proteins G3BP1 / 2 of stress granules. The oligonucleotides in these drugs are all composed of 20 bases, with 5 bases at each end modified with 2'-O-methoxyethyl, and 10 consecutive ordinary bases in the middle to ensure targeting specificity. Simultaneously, the entire nucleic acid chain is modified with thiophosphorylation. The oligonucleotide molecules disclosed in this invention possess targeting specificity, high molecular activity, and in vivo metabolic stability, providing research directions and candidate drugs for clinical targeting of stress granules and improvement of neurodegenerative diseases such as ALS.