33 results about "Bioindicator" patented technology

A biological indicator includes: a BI housing; a germinant container inside the BI housing and housing a germinant composition; a germinant releaser configured to release the germinant composition from the germinant container; a germinant releaser support supporting the germinant releaser and configured to bring the germinant releaser into contact with the germinant container upon application of a force to the germinant releaser support or the germinant container; a first spore carrier inside the BI housing, the first spore carrier having a plurality of spores deposited at a first surface thereof; and an imaging window at a first surface of the BI housing. A BI reader is configured to detect and quantify the presence of live spores in the BI, and includes an excitation source, a camera for capturing images of the spores over time, and a processor for analyzing the images to determine the presence of live spores.

The utility model provides a biological indicator which comprises an outer tube, the top end of the outer tube is sleeved with an end cover, a sealing plug is inserted in the end cover, filter paper is arranged in the end cover, the sealing plug is attached to the top face of the filter paper, a glass reagent tube is arranged in the outer tube, a bacterial sheet is arranged on the bottom face in the outer tube, and the bacterial sheet is bent to be of a U-shaped structure. The bottom end of the glass reagent tube is inserted into the U-shaped structure of the bacterial tablet; a positioning groove is formed in the bottom end of the outer tube; the packaging box comprises a box body for containing the biological indicator, and a packaging mechanism is connected to one side of the box body in an inserted mode. According to the utility model, the biological indicator is put into the packaging mechanism, and the packaging mechanism is inserted into the box body, so that the biological indicator can be well packaged and protected, and when the sterilization effect is detected, only the biological indicator subjected to high-temperature sterilization needs to be put into the box body, and the packaging mechanism is inserted into the box body. The turning and clamping assembly and the clamping column are matched to pinch off the internal structure of the biological indicator, and there is no need to find a clamp for pinch-off operation.

The biological indicator includes a BI housing, a germinant container that holds a germinant composition within the BI housing, a germinant releaser configured to release the germinant composition from the germinant container, a germinant releaser support that supports the germinant releaser, the germinant releaser support configured to bring the germinant releaser into contact with the germinant container when a force is applied to the germinant releaser support or the germinant container, a first spore carrier within the BI housing, the first spore carrier having a plurality of spores deposited on a first side thereof, and an imaging window on a first face of the BI housing. The BI reader is configured to detect and quantify the presence of viable spores within the BI and includes an excitation source, a camera for capturing images of the spores over time, and a processor for analyzing the images to determine the presence of viable spores.

This invention belongs to the field of ecological environment monitoring technology and relates to a multi-level bioindicator method for the effective phytotoxicity of heavy metal-like substances / heavy metals. The method includes the following steps: S1. Obtaining plant samples affected by the soil or water body to be tested; S2. Measuring the activity of superoxide dismutase (SOD), gibberellin (GA), and chlorophyll content in the plant samples; S3. Based on the measured results of SOD activity, plant hormone content, and chlorophyll content, and their changes over time, classifying and assessing the effective phytotoxicity effects of heavy metal-like substances or heavy metals. This invention is the first to propose a unified three-level bioindicator method (SOD activity, GA hormone, and chlorophyll) that can effectively reflect soil pollution levels for typical heavy metal-like substances / heavy metals present in the actual environment, enabling a simpler assessment of the degree of heavy metal pollution in actual soil.

A self-contained biological indicator is provided. The biological indicator includes a housing having at least one liquid-impermeable wall that forms an opening into a compartment. Disposed in the housing are a plurality of test microorganisms; an aqueous liquid medium disposed in an openable container; and a pH indicator dye substrate having a pH indicator dye bound thereto. The pH indicator is not disposed in or in liquid contact with the aqueous liquid medium. The biological indicator further comprises a nutrient composition that facilitates germination and / or outgrowth of the test microorganism, if viable; The nutrient composition can be disposed in the housing or is disposed in the openable container that is in selective fluid communication with the compartment.

The invention relates to the technical field of biology, in particular to a sterilization biological indicator and application thereof. The invention provides a biological indicator composed of sulfhydrylated spores containing bacillus atrophaeus and a spore culture solution containing a gold nanoprobe. The biological indicator is used for monitoring the sterilization effect, solves the problems of low spore detection speed of bacillus atrophaeus after ethylene oxide sterilization and high use cost of a rapid ethylene oxide indicator, can realize rapid detection within 10 minutes after sterilization, and does not need a complex instrument. The method has a wide application prospect in the monitoring of the sterilization effect of ethylene oxide sterilization equipment.

The crushing and shaking device comprises a base, a support, a shaking assembly and a crushing assembly, the base is provided with a cavity with an upward opening, the support is arranged on the base, the shaking assembly comprises a rotating disc and a power part, the rotating disc is rotationally arranged on the base, a plurality of indicator grooves are formed in the rotating disc, and the indicator grooves are arranged on the rotating disc. The power part is arranged in the cavity, the power part is connected with the rotating disc and used for driving the rotating disc to rotate forwards and backwards on the base, and the crushing assembly is arranged on the support and used for abutting against the rotating disc to press the indicator grooves. According to the utility model, a plurality of biological indicators placed in the indicator grooves on the turntable are firstly crushed through the crushing assembly, so that a culture solution flows out, and then the turntable is driven by the power part to rotate forwards and backwards on the base, so that a shaking effect is generated, the culture solution is fully mixed, the plurality of biological indicators can be crushed at one time, and the working efficiency of medical personnel is improved.

This application relates to the field of combustion product testing, specifically a smoke toxicity testing device. It includes a base on which multiple independent mouse cages are fixed, each cage having a gas inlet and a gas outlet. This smoke toxicity testing device directly assesses smoke toxicity by placing live mice in the cages, introducing smoke into the cages, and observing the mice's reactions. Using live mice as a bioindicator for assessing smoke toxicity simulates the potential harm to humans in real fire scenarios, intuitively reflecting the impact of smoke on organisms, and more effectively assessing smoke toxicity. This provides researchers with a direct method for assessing smoke toxicity, offering a basis for improving fire prevention and response measures.

A biological indicator (100) for use in a liquid-chemical decontamination system is disclosed. The biological indicator may include a housing (102) and a cap (106) coupled to the housing. The cap may comprise a liquid chamber and at least two ports. One of the ports may connect to a liquid passage in the cap such that liquids such as liquid-chemical decontaminants may be introduced and removed from the biological indicator via this port.

The utility model discloses a dry heat sterilization biological indicator resistance instrument, which comprises a shell, and is characterized in that a platform is arranged in the shell, a base, a lifting mechanism and a testing mechanism are arranged on the platform, a limiting part is arranged on the base, a testing chamber is formed between the base and the limiting part, and the testing mechanism is arranged in the testing chamber. The testing mechanism comprises a testing table which is locally and movably arranged in the testing chamber, the testing table can be sealed with the limiting part so as to limit the testing chamber to be communicated with the atmosphere, and the dry heat sterilization biological indicator resistance instrument is convenient to improve, good in sealing performance, accurate in testing data, convenient to operate and simple in structure.

The utility model discloses a self-contained biological indicator structure which comprises a cylinder body, a spore carrier is placed at the bottom of an inner cavity of the cylinder body, a second through hole is formed in the upper end of the cylinder body, and a puncture needle is fixedly connected to the lower end of the left side of the inner cavity of the cylinder body. And a threaded seat is fixedly connected to the upper end of the outer surface of the barrel and located below the second through hole. Through the arrangement of the first through hole and the second through hole, the environment in the cylinder body can be communicated with the environment in sterilization equipment in the sterilization operation process, so that a spore carrier in the cylinder body can be conveniently sterilized, and meanwhile, through the arrangement of the threaded seat, the clamping hole, the clamping convex block, the plastic baffle ring and the plastic connecting strip, the spore carrier can be conveniently sterilized. The protective cover can be effectively supported and limited, the protective cover is prevented from loosening from the top of the barrel, and meanwhile, the protective cover can be effectively prevented from rotating along the thread on the surface of the threaded seat, and dislocation between the first through hole and the second through hole is avoided.

The invention relates to a bioindicator and a method for using the bioindicator for microbiological testing of washing machines. The device according to the invention allows a safe, reliable, cost-effective and easy-to-use microbiological test of the disinfection performance of washing machines. The invention further relates to a use of the bioindicator and a kit comprising 10 bioindicators. In particular, the invention relates to a closed bioindicator for a verification of disinfecting washing processes.

The invention discloses a disinfection cabin hatch cover of medical waste disinfection equipment, and relates to the technical field of medical waste treatment, the disinfection cabin hatch cover comprises a support installed at a hatch opening and a cross beam hinged to the support, and further comprises a hatch cover body located below the cross beam, and an observation pipeline and a locking mechanism are installed between the hatch cover body and the cross beam in a penetrating mode; the observation pipeline is movably installed in the hatch cover body, the observation pipeline is rotationally sleeved with an adjusting sleeve piece for driving the locking mechanism, a lock hole corresponding to the locking mechanism is formed in the support, the biological indicator storage pipe is fixed to the bottom face of the hatch cover body, and the two ends of the biological indicator storage pipe are open; an anti-disengaging limiting assembly for covering the opening and locking the locking mechanism is installed in the hatch cover body. By arranging the locking mechanism and the adjusting sleeve piece, rapid locking and unlocking of the hatch cover are achieved, and meanwhile whether the locking mechanism is located at the correct locking position or not is judged through further clamping connection between the anti-disengaging limiting assembly and the locking mechanism.

The invention relates to the technical field of gardens, and discloses an arc-shaped surface shrub planting and pruning method, which comprises the following steps: determining a shrub planting area through soil sampling detection and topographic mapping, the planting area comprises a lawn earth surface and a shrub earth surface, and a U-shaped water collecting ditch is arranged between the lawn earth surface and the shrub earth surface; a biological indicator is adopted to conduct qualitative evaluation on the soil ecological environment of the planting area, a specific soil improvement scheme is customized according to the evaluation result, and the specific soil improvement scheme comprises modifier formula adjustment and application mode optimization; through full-chain technical innovation of soil improvement, rainwater interception, three-dimensional layout, dynamic pruning and data driving, the following core breakthroughs are achieved: a sustainable slope ecological system can be constructed, the landscape effect is relatively strong, the cost is relatively low, and the system is suitable for scenes such as urban road isolation belts and park landscape belts, and has remarkable popularization and application values.

Provided are a condition change detection system, a condition change detection program, and a vital data complementation method that can accurately detect changes in a subject's condition while suppressing a decrease in detection accuracy even when data is missing. [Solution] A condition change detection system 100 is configured to include a biological information measurement device 101 that measures the vital signs of a subject, and a host device 200 that manages changes in the subject's condition. The host device 200 is primarily configured to include a memory unit 201, an input unit 202, a control unit 203, an output unit 204, and a communication unit 205. In this case, the control unit 203 includes a preprocessing unit 203a that processes acquired vital data into a state suitable for detection, an index calculation unit 203b that calculates bioindicators using the processed data, a change detection unit 203c that detects changes in the subject's condition based on the calculated bioindicators, and a condition notification unit 203d that notifies the subject of changes in condition.

1. The name of the design product: fast biological reader (piano). 2. The use of the design product: through monitoring the survival state of microorganisms in biological indicators, to determine whether medical devices, laboratory equipment and other articles meet the sterile requirements. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view 1.

The utility model discloses a biological indicator protection device and a bioreactor, and belongs to the technical field of biological medicine equipment. In order to solve the problems that a biological indicator accidentally falls off in the sterilization process and is hit by a stirring paddle and the like, structures such as a hollow pipe, a plug and an indicator placing bin are mainly adopted, and the indicator placing bin is fixed on a bioreactor tank cover through a sealing ring and a threaded structure. The biological indicator protection device ensures that the position of the biological indicator is stable in the sterilization process, the indicator is prevented from being damaged or polluting reaction substances, and meanwhile operation efficiency and verification accuracy are improved. According to the utility model, the safety protection of the biological indicator and the high efficiency and reliability of sterile verification can be realized.

A system for assessing efficacy of a sterilization process is disclosed. The system includes a biological indicator, a receptacle configured to receive the biological indicator, an actuator mechanism, and a sensing system operatively coupled to the actuator mechanism. A method of using the system for assessing efficacy of a sterilization process is also disclosed.

The invention relates to a bioindicator and a method for using the bioindicator for microbiological testing of washing machines. The device according to the invention allows a safe, reliable, cost-effective and easy-to-use microbiological test of the disinfection performance of washing machines. The invention further relates to a use of the bioindicator and a kit comprising 10 bioindicators. In particular, the invention relates to a closed bioindicator for a verification of disinfecting washing processes.

According to the scheme, the self-contained biological indicator inoculation tool comprises a main body which is provided with an opening for placing a biological indicator and a containing cavity for inserting and placing the biological indicator; the top block is positioned at the top of the accommodating cavity and is provided with a guide surface; the side bulges are positioned on the inner wall of the accommodating cavity and are symmetrically arranged; after entering the containing cavity through the opening, the biological indicator can swing with the bottom of the biological indicator as a fulcrum, when the biological indicator swings towards the ejector block, a cap plug of the biological indicator can be pressed through the guide face of the ejector block, and meanwhile the side face protrusion in the containing cavity can extrude the side wall of the biological indicator so that a culture medium tube of the biological indicator can be broken through extrusion. The structure is simple, operation is convenient and cost is low.

The utility model discloses steam sterilization biological indicator D value testing equipment which comprises a machine body, a testing chamber is arranged on the machine body, one end of the testing chamber is communicated with a pipe body, the other end of the testing chamber is provided with a cover body, the cover body is detachably connected with the testing chamber, and a sealing mechanism is arranged between the cover body and the testing chamber. The sealing mechanism comprises a first sealing piece used for sealing the cover body and the inner wall of the test chamber in a matched mode and a second sealing piece used for sealing the cover body and the side face, facing one side of the cover body, of the test chamber in a matched mode, and the cover body and the test chamber are closed after being connected. The structure is simple.

The utility model relates to a related tool for biological indicator detection, which comprises a fast-assembly sealing ring and a mesh basket, the mesh basket is arranged at the bottom of the fast-assembly sealing ring, the mesh basket is used for being arranged at the position of a pipeline temperature sensor or randomly placed in a pipeline and a storage tank, and a microbial indicator is convenient to store and take in the mesh basket. When the device is placed at the position of a pipeline temperature sensor and used for SIP sterilization, a biological indicator can be conveniently stored and taken out, it is guaranteed that the biological indicator cannot be lost during sterilization, the device placed in the pipeline is made of 316L stainless steel, other foreign matter cannot be introduced during sterilization, and the pipeline cannot be polluted; the stainless steel net basket is an independent stainless steel net basket and can be placed at any position in a pipeline and a storage tank, the biological indicator can be conveniently stored and taken out, it is guaranteed that the biological indicator cannot be lost, the net basket placed in the pipeline is made of 316L stainless steel, and other foreign matter cannot be introduced in the sterilization process.

According to the scheme, the manual gland pipe clamping tool for the self-contained biological indicator comprises a base, a plurality of installation grooves used for installing the biological indicator are formed in the base, and an open hole is formed in the side, facing a pipe breaking movable block, of each installation groove; the pipe breaking moving block is matched with the base and is used for extruding a shell of the biological indicator, so that an ampoule straight pipe in the biological indicator is broken; the reset spring is arranged between the pipe breaking movable block and the base; the tube breaking shaft is provided with a breaking cam and a gland cam in the length direction of the tube breaking shaft, and the tube breaking movable block is driven to extrude the biological indicator by driving the breaking cam to rotate; the cover pressing swing rod is rotationally connected with the base and is matched with the cover pressing cam in an abutting manner; the rotary tension spring is arranged between the gland swing rod and the base; and the manual pressing swing rod is connected with the pipe breaking shaft. The convenience of capping and pipe clamping after sterilization of the self-contained biological indicator can be improved.

The invention discloses a biological indicator recognition and detection method. Detection is performed through a biological indicator recognition and detection device. During detection, the culture temperature is set, the optical filter switching device is switched to a non-filtering mode, an indicator is photographed through a camera to obtain an initial state image, the type of the indicator is recognized, and a corresponding detection algorithm is matched according to the type of the indicator; then switching to a fluorescent filtering mode through an optical filter switching device, turning on an ultraviolet light source, and performing photographing detection on the indicator through a camera: culturing the indicator after detection is completed, and photographing the indicator through the camera after culture is completed to obtain a final state image. Before the indicator is detected, the type of the indicator can be automatically identified; after the indicator type is obtained, the system can automatically match a corresponding indicator detection algorithm, so that different types of biological indicators can be compatible at the same time, and the universality of detection equipment is improved.

A process for determining the viability of a biological indicator includes exposing the biological indicator to a viability detection medium, the biological indicator including test microorganisms, the exposing the biological indicator to the viability detection medium producing a gaseous reaction product when one or more of the test microorganisms are viable. The presence or absence of the gaseous reaction product produced by the biological indicator combined with the viability detection medium is detected with a sensing device, the sensing device comprising a capacitive sensor, an electro-mechanical sensor, or a resistive sensor, wherein the presence of the gaseous reaction product indicates the presence of viable test microorganisms and the absence of the gaseous reaction product indicates the absence of viable test microorganisms. A sterilization detection device includes a container configured to contain the biological indicator, a viability detection medium, and the sensing device.

The invention discloses a suspension type moist heat sterilization biological indicator suitable for room temperature storage as well as a preparation method and application thereof, and belongs to the technical field of microbiological detection and analysis instruments. The suspension type moist heat sterilization biological indicator creatively prepared by adding D-phenylalanine or D-tyrosine can well inhibit spores, so that the spores can be effectively prevented from being damaged by the spores; the shelf life of the product can be prolonged; the inhibition on spores can be relieved, so that the spores can germinate under an unqualified sterilization condition, and the generation of false negative of a suspension type biological indicator is avoided.

The present invention provides a method of detecting an unrecognised environmental polluting event, comprising: (i) measuring the level of one or more bioindicators in a sample obtained from individuals in a first geospatially defined population; and (ii) comparing the level of the one or more bioindicators in the first geospatially defined population to the level of the same one or more bioindicators in a distinct geospatially defined population, or a control value; wherein a statistically significant difference in the level of the one or more bioindicators between the first geospatially defined population and the distinct geospatially defined population, or the control value, is indicative that the first geospatially defined population has been exposed to an environmental polluting event.

A biological indicator package includes an intermediate support member, a vapor permeable pouch, a biological indicator contained in the pouch, and a tab. The pouch protrudes from a first side of the intermediate support member. The biological indicator includes an organism carrier and a spore loaded onto the carrier. The tab protrudes from a second side of the intermediate support member. The tab includes a tab front layer and a tab back layer. The tab front layer or the tab back layer, or both, may have a tab adhesive layer configured to adhere the tab front layer to the tab back layer. The tab adhesive layer is configured to enable peeling apart of the tab front layer away from the tab back layer to expose the tab adhesive layer. The tab adhesive layer, once exposed, is configured to adhere to a surface during a decontamination cycle of a decontamination process.