The present invention relates to the technical field of biological material preservation, and particularly discloses an
RNA preservation tube, which comprises: an
amino acid component selected from at least one of
glycine and a derivative thereof; the EDTA
metal chelating agent is selected from at least one of EDTA
alkali metal salts and hydrates thereof; a
preservative component; optionally comprising a
pH indicator; the
storage tube is provided with a sealed cavity for storing an
RNA solution, and the volume of the cavity is 1-20ml; through combination of a
glycine-EDTA synergistic buffer
system and an
imidazolidinyl urea preservative, long-acting stable preservation of an
RNA sample in an
extreme environment is realized,
metal ions can be dynamically chelated and the pH value is maintained in a range of 6.8-7.5 through a specific ratio of
glycine to EDTA salt, a multi-
protection mechanism is formed by combining a tube wall
nucleic acid adsorption inhibition treatment technology, and the RNA sample can be stably preserved in the
extreme environment through the combination of the glycine-EDTA synergistic buffer
system and the
imidazolidinyl urea preservative. And the loss caused by RNA
enzyme activity, acid-base degradation and physical adsorption is effectively blocked, and the product is especially suitable for high-temperature transportation or long-term normal-temperature storage scenes.