114 results about "Hydroxylamine Hydrochloride" patented technology

The application discloses a method for preparing a CGRP receptor antagonistic intermediate, and belongs to the field of synthesis of medical intermediates. Compound 1 is used as a raw material, reacts with hydroxylamine hydrochloride in an organic solvent to generate an intermediate 2, and then reacts in the presence of a reducing agent to obtain a remikiren intermediate 3. The application is characterized in that a large steric hindrance silicon group is used as the R substituent in the compound 1, so that high stereoselectivity is ensured in the reduction reaction. The key intermediate obtained by using the method has high chiral purity, and the operation is simple, so that the industrial production of the product in the later stage can be realized.

The invention relates to the technical field of precious metal recovery, in particular to a method and system for recovering gold, silver, palladium and platinum from silver anode slime. S2, palladium precipitation: adding a potassium-magnesium mixture and sodium chlorate into the pre-impregnation liquid obtained in S1 to obtain palladium precipitation residues and platinum precipitation liquid; s3, separating gold; s4, platinum and palladium precipitation: adding a potassium-magnesium mixture and sodium chlorate into the gold separation liquid obtained in S3 to obtain platinum and palladium precipitation residues and platinum and palladium precipitation post-liquid; s5, gold is reduced; s6, platinum and palladium separation, wherein hydroxylamine hydrochloride is added into the platinum and palladium precipitation residues obtained in the step S4, and palladium separation liquid and platinum precipitation residues are obtained; 7, platinum purification, wherein hydroxylamine hydrochloride is added into the platinum precipitation residues obtained in the step 6, and platinum separation liquid is obtained; s8, carrying out primary palladium deposition; s9, carrying out secondary palladium deposition; and S10, palladium is reduced. The recovery rate of palladium is 99% or above, the recovery rate of platinum is 99% or above, the purity of platinum is 99.9%, the purity of palladium is 99.95%, the recovery rate of silver is 98.5% or above, and the recovery rate of gold is 99% or above.

The invention provides a preparation method of milbemycin oxime A4, which comprises the following steps: under an acidic condition, carrying out hydrolysis disaccharide removal reaction on tenvermectin B to obtain tenvermectin B aglycone; the preparation method comprises the following steps: carrying out silicon-based protection on tenvermectin B aglycone by adopting a silicon-based protection reagent to obtain 5-hydroxyl silicon-based tenvermectin B aglycone; the preparation method comprises the following steps: brominating 5-hydroxyl silicon-based tenvermectin B aglycone by adopting a brominating reagent to obtain 13-bromine-5-hydroxyl silicon-based protected tenvermectin B aglycone; the preparation method comprises the following steps: reducing 13-bromo-5-hydroxyl silicon group protected tenvermectin B aglycone by using a reducing agent to obtain 5-hydroxyl silicon group protected milbemycins A4; the milbemycins A4 protected by the 5-hydroxyl silicon group is subjected to desilicication protection treatment, and the milbemycins A4 is obtained; oxidizing milbemycins A4 by adopting an oxidizing agent to obtain 5-ketomilbemycins A4; the preparation method comprises the following steps: reacting 5-ketomilbemycins A4 with hydroxylamine hydrochloride to obtain milbemycins A4, and efficiently preparing the active component milbemycins A4 single component by taking tenvermectin B as a raw material.

The invention relates to the technical field of palladium recovery, in particular to a method for recovering palladium. According to the technical scheme, the method comprises a precipitant pre-synthesis stage, a targeted palladium precipitation stage and a multi-stage reduction purification stage, and the precipitant pre-synthesis stage comprises the step of adding 10-15 parts by mass of butanedione, 18-30 parts by mass of hydroxylamine hydrochloride and 0.1-0.3 part by mass of iron phthalocyanine into a reaction kettle. Through a composite precipitator system and a multi-stage reduction process, the method has safety and high efficiency: flammable and explosive solvents such as ethanol and highly toxic reducing agents such as hydrazine hydrate are not needed, so that the potential safety hazard of production and the environment-friendly treatment cost are remarkably reduced; high-selectivity capture and efficient reduction of palladium are achieved through magnetic separation of magnetic nano-microspheres, induced precipitation of nitrogen-doped graphene quantum dots and a staged temperature-control and pressure-control reduction technology, the palladium recovery rate and purity are high, the process period is short, operation is controllable, and the method is suitable for industrial continuous production.

The application discloses a synthesis method of afugan, which comprises the following steps: 1-[3-chloro-5-(trifluoromethyl)phenyl]-2,2,2-trifluoroacetone and 4-acetylnaphthalene carboxylic acid are added into a solvent, a base is added, DMAP is added after complete reaction at 50-80 DEG C, acetic anhydride is added dropwise, tetrabutylammonium bromide is added after complete reaction, and an aqueous solution of sodium hydroxide and hydroxylamine hydrochloride is added, and reaction is carried out at 0-5 DEG C, so that an intermediate is obtained; the intermediate is reacted with acyl chloride under the action of DMF and dichloromethane, so that 4-(5-(3-chloro-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole-3-yl)-1-naphthalene carboxylic chloride is prepared; 2-amino-N-(2,2,2-trifluoroethyl)acetamide hydrochloride and a dichloromethane solution of a base are added dropwise, and reaction is carried out at 0-5 DEG C, so that afugan is obtained. The method has a short route, high yield and suitability for large-scale industrial production.

The invention relates to the technical field of uranium extraction fiber membranes, and discloses a preparation method of an MXene / PVDF / PAO photo-thermal-piezoelectric composite fiber membrane, and the preparation method comprises the following steps: S1, dissolving PAN in DMF, adding hydroxylamine hydrochloride and NaOH, and stirring to obtain a spinning solution I; s2, PVDF is dissolved in DMF, multiple layers of MXene materials are added, and a uniform spinning solution II is obtained through stirring; and S3, preparing the MXene / PVDF / PAO fiber membrane from the spinning solution I and the spinning solution II in a double-spinning form by using an electrostatic spinning device. And jointly assembling the PAO, the PVDF nano particles and the Mxene nano sheets into the electrostatic spinning membrane. Wave energy excites the piezoelectric effect of PVDF, and light energy is absorbed by Mxene. Compared with an existing scheme, water flow resistance is smaller, adsorption sites are more, and large-scale sea tests are better facilitated.

This invention belongs to the field of soil manganese extraction technology, and discloses a stepwise extraction method and application for manganese species in soil. First, exchangeable manganese is extracted using magnesium chloride; then, manganese carbonate and sulfides are extracted using hydrochloric acid; next, active Mn(III) bound to organic matter is extracted using pyrophosphate solution under alkaline pH; then, manganese oxides are dissolved using hydroxylamine hydrochloride; and finally, manganese bound to crystalline iron and manganese oxides is extracted using sodium dithionite solution. This stepwise extraction scheme accurately quantifies the concentration of active Mn(III) species bound to organic matter in the soil. Experimental results show that the extraction method of this invention can effectively separate different forms of manganese in soil. In particular, PP extraction successfully distinguishes Mn(III) bound to organic matter without introducing interfering substances such as iron minerals that may interfere with dissolution.

The invention discloses an organic peroxide reaction endpoint rapid detection method and application thereof, and belongs to the technical field of organic chemistry. The invention aims to solve the technical problems that the reaction endpoint of an organic peroxide initiator is difficult to judge, the generated organic peroxide is easy to decompose due to too long reaction time, and the reaction is incomplete and raw materials are remained due to too short reaction time, and provides a rapid detection method for acyl chloride residues in the organic peroxide reaction process. Therefore, the reaction endpoint is determined. According to the technical scheme, the method for rapidly detecting the reaction endpoint of the organic peroxide is characterized in that in the reaction process of an organic peroxide initiator, acyl chloride is gradually consumed, the content is reduced, and the acyl chloride completely reacts when the reaction endpoint is reached. Through reaction of different acyl chloride concentrations and hydroxylamine hydrochloride, a standard curve or a color card is established, the residual amount of acyl chloride is judged, and the reaction endpoint is accurately judged.

The application discloses a hydroxylamine hydrochloride detection method in azithromycin dry suspension, and relates to the trace detection field. The method uses isoamyl aldehyde as a derivatizing agent, generates isoamyl aldoxime by performing derivatization treatment on a sample to be measured, and then uses N-nitrosodiisopropylamine as an internal standard substance to quantitatively determine the isoamyl aldoxime by using liquid chromatography-tandem mass spectrometry. The detection method adopts an isoamyl aldehyde derivatizing agent-N-nitrosodiisopropylamine internal standard substance system, can correct detection errors caused by factors such as matrix effect, pretreatment loss and derivatization efficiency fluctuation, and improves the accuracy and sensitivity of the trace hydroxylamine hydrochloride detection result, thereby guaranteeing the safety of the medicine.

The invention relates to the technical field of graphene modification, and particularly discloses a preparation method of modified graphene for lubricating oil, which comprises the following steps: ultrasonically dispersing graphene in water to obtain a graphene dispersion liquid; potassium octadecyl benzene sulfonate is added into the graphene dispersion liquid, and a stirring reaction is performed for 10-20 min; then adding ammonium molybdate and sodium sulfide into the system, adjusting the pH value of the reaction system to 4.5-6, and reacting for 1-2 hours under the reflux stirring action at 60-110 DEG C; adding hydroxylamine hydrochloride into the reaction system, and continuously stirring to react for 2-4 hours; and finally, carrying out centrifugal separation on the reaction liquid, washing with ethanol and distilled water for multiple times, and carrying out centrifugal separation to obtain the modified graphene. According to the preparation method of the modified graphene provided by the invention, a stable and uniform lubrication enhancement layer can be constructed on the surface of the graphene in situ, so that the graphene is endowed with excellent oil solubility and oil phase dispersion stability.

The invention relates to the technical field of organic synthesis, in particular to the field of IPC C07D239, and more particularly relates to a synthesis method of a phenyl isoxazoline compound. Comprising the following steps: step 1, using a benzaldehyde compound as an initial raw material, and reacting with hydroxylamine hydrochloride to generate a benzaldoxime compound; 2, carrying out a chlorination reaction on the benzaldoxime compound generated in the step 1 and liquid chlorine through a microchannel reactor to generate a chlorinated benzaldoxime compound; and 3, carrying out ring closing on the chlorobenzaldoxime compound generated in the step 2 and an alkene compound to obtain the phenyl isoxazoline compound. A metal catalyst is not used in the preparation method, so that the solid waste treatment cost is reduced; in the step 2, a continuous flow reaction technology of a microchannel reactor is adopted, the reaction time is shortened, compared with a kettle type intermittent process, the productivity is greatly improved, and the reaction safety is higher.

This invention relates to the field of bionanomaterials technology, and particularly to mitochondrial-targeting nanomaterials capable of releasing HNO, their preparation methods, and applications. The preparation method of the mitochondrial-targeting nanomaterials capable of releasing HNO includes the following steps: synthesis of a silanized HNO donor: hydroxylamine hydrochloride is dissolved in a mixed solvent of anhydrous tetrahydrofuran and anhydrous pyridine, and a dichloromethane solution of 2-(4-chlorosulfonylphenyl)ethyltrimethoxysilane is added. The mixture is stirred at room temperature, and after post-treatment, a silanized HNO donor is obtained; synthesis of aminated carbon dots: chitosan, ethylenediamine, and mercaptosuccinic acid are dispersed in deionized water, and concentrated hydrochloric acid is added and stirred until dissolved. This preparation method can prepare mitochondrial-targeting nanomaterials capable of releasing HNO, achieving precise delivery, controlled release, and visual tracking of HNO to cardiac mitochondria, solving the technical problems of traditional HNO donors' inability to achieve stable loading on carriers and lack of mitochondrial targeting ability.

The invention provides a preparation process and system of N-benzyl hydroxylamine hydrochloride, and the preparation process utilizes a microchannel reactor and a film concentration device to realize synthesis of a target product through a two-step method. The method comprises the following steps: firstly, continuously pumping dibenzylamine, an auxiliary agent and hydrogen peroxide into a micro-channel reactor, and carrying out accurate temperature control and efficient mixing under a micro-scale to promote an oxidation reaction to be rapidly completed so as to generate a key nitrone intermediate; the step effectively avoids the dangerous thermal runaway phenomenon possibly occurring in a traditional reaction kettle, and the operation safety is improved. Then, introducing the nitrone intermediate and hydrochloric acid into a film concentration device; in the device, the nitrone intermediate is hydrolyzed under an acidic condition, and meanwhile, a reaction solution can be quickly evaporated by a film concentration technology, so that a solvent and byproducts generated along with the reaction are efficiently removed. The thin film concentration technology not only inhibits the occurrence of side reactions, but also ensures the high yield and high purity of the final product.

The invention relates to the technical field of high polymer materials, and discloses a fully biodegradable mulching film for corn for seed production and a preparation method thereof, the fully biodegradable mulching film comprises the following components by weight: 65-75 parts of polylactic acid, 4-6 parts of modified polyester, 8-12 parts of biomass charcoal, 2-3 parts of acetyl tributyl citrate, and 0.4-0.5 part of an antioxidant 1010; the preparation method of the modified polyester comprises the following steps: synthesizing an intermediate 1 by taking 2-hydroxyadipaldehyde and hydroxylamine hydrochloride as raw materials, and then esterifying, oxidizing and curing to obtain the modified polyester. The full-biodegradable mulching film for the corn for seed production has relatively good tensile property and degradable effect.

The invention discloses a preparation method of a biochar-zinc sulfide-tungsten sulfide heterojunction composite material, and the scheme comprises the following steps: S1, dissolving sodium tungstate, hydroxylamine hydrochloride, sodium hydroxide, thiourea and zinc chloride in deionized water, and uniformly stirring to obtain a light yellow transparent reaction solution; s2, biological carbon is prepared, the reaction liquid and the biological carbon are mixed in a reaction kettle and then subjected to a hydrothermal reaction for 8-48 h at the constant temperature, and the constant temperature is any one of the temperature values ranging from 180 DEG C to 240 DEG C; s3, filtering, cleaning and drying a product obtained in the step S2 to obtain a heterojunction composite material precursor; s4, the heterojunction composite material precursor is subjected to calcination treatment in the inert gas atmosphere, the biochar-zinc sulfide-tungsten sulfide heterojunction composite material is obtained, and the calcination temperature ranges from 850 DEG C to 950 DEG C.

The invention discloses a method for co-production of 2, 4-dichloro-5-fluoroacetophenone and hydroxylamine hydrochloride, and belongs to the technical field of organic chemical industry, 2, 4-dichlorofluorobenzene is used as a raw material, alkylation and reaction with tert-butyl nitrite are performed to generate oxime, and then hydrochloric acid hydrolysis is performed to generate 2, 4-dichloro-5-fluoroacetophenone and hydroxylamine hydrochloride; according to the method, co-production of the 2, 4-dichloro-5-fluoroacetophenone and the hydroxylamine hydrochloride is innovatively realized, not only are high yield and high purity of the target product 2, 4-dichloro-5-fluoroacetophenone ensured, but also the nitrogen element in the reaction is recycled and converted into the hydroxylamine hydrochloride with high additional value, and the atom economy is remarkably improved; according to the method, the operation process is greatly simplified, the use of dangerous reagents is avoided, and the intrinsic safety and environmental friendliness of the process are improved from the source; the method is simple to operate, safe and environment-friendly, the production cost is effectively reduced, and the market competitiveness of the product is enhanced.

The invention provides a preparation method of acacia gum nano-composite hydrogel. The preparation method comprises the following steps: S1, mixing an acacia gum aqueous solution with a free radical initiator, and then sequentially adding acrylonitrile, CuFe2O4 nanoparticles and a cross-linking agent into the mixture to obtain the acacia gum nano composite hydrogel. The acacia gum nano-composite hydrogel combines the characteristics of a natural polymer, a synthetic polymer and inorganic nanoparticles, and is an effective adsorbent for removing heavy metals in an aqueous solution, the prepared magnetic hydrogel is treated by hydroxylamine hydrochloride, so that a nitrile group is converted into an amidoxime group to serve as a bidentate ligand, and the adsorption capacity of the hydrogel is improved. The existence of CuFe2O4 in the acacia gum nano-composite hydrogel makes the recoverable magnetic hydrogel possible, the recoverable magnetic hydrogel can be easily removed from an aqueous solution and regenerated, and after three continuous cycles, the recoverable magnetic hydrogel still has high heavy metal adsorption capacity.

The invention discloses a preparation method of salicylhydroxamic acid, and relates to the technical field of flotation reagents and preparation thereof, in particular to the preparation method of salicylhydroxamic acid, which comprises the following steps: in the presence of an organic solvent and water, adding a phase transfer catalyst, alkali and a hydroxylamine hydrochloride aqueous solution into a reaction tank, uniformly stirring, adding methyl salicylate, and reacting for 2-4 hours at the temperature of 50-60 DEG C; after the reaction is finished, concentrated sulfuric acid is added to obtain salicylhydroxamic acid, through the arrangement of the reaction tank, a stirring rod, an extrusion bag and a slope ring plate, the stirring rod can be driven by a driving column to rotate, and the downward moving-resetting circulation of the stirring rod is achieved through the cooperation of an adjusting rod, a top block and the slope ring plate; the extrusion bag is driven to press and grind sodium hydroxide particles gathered on the inner bottom surface of the reaction tank, particle aggregation is broken, the particles are refined, the sodium hydroxide dissolution rate is increased, local high temperature is prevented from damaging key components such as hydroxylamine and methyl salicylate, generation of non-target substances is reduced, and the yield and purity of salicylhydroxamic acid are improved.

The invention discloses a low-toxicity method for measuring soil nitrate nitrogen 15N based on an optical cavity ring-down technology, which comprises the following steps: extracting 1 g of fresh soil with 10 ml of 2M KCl, determining the content of nitrate nitrogen in the soil through a flow analyzer, and diluting to 0.14-0.28 mgN / ml to obtain a soil extract for later use; the method comprises the following steps: adding 2ml of a soil leaching solution into a headspace bottle for later use, and then sequentially adding 0.2 ml of a 0.01 M VCl3 solution and 0.5 ml of 0.02 M hydroxylamine hydrochloride; transferring to a constant-temperature shaking table at the temperature of 37 DEG C, reacting for 16 hours at the speed of 125 rpm / min, extracting a gas sample by using a gas-tight injector, and injecting into an isotope measuring instrument based on an optical cavity ring-down technology to measure 15N of N2O as 15N of nitrate nitrogen. According to the method, the analysis efficiency of the whole experiment can be effectively improved, environmental hazards caused by use of high-toxicity chemical reagents are reduced, and meanwhile, the analysis cost is effectively reduced.

This invention relates to the field of bionanomaterials technology, and particularly to mitochondrial-targeting nanomaterials based on ZnO quantum dots, their preparation methods, and applications. The preparation method of mitochondrial-targeting nanomaterials based on ZnO quantum dots includes the following steps: synthesis of silanized HNO donor: hydroxylamine hydrochloride is dissolved in a mixed solvent of anhydrous tetrahydrofuran and anhydrous pyridine, and a dichloromethane solution of 2-(4-chlorosulfonylphenyl)ethyltrimethoxysilane is added. The reaction is carried out with stirring at room temperature, and after post-treatment, silanized HNO donor is obtained; synthesis of zinc oxide quantum dots: zinc acetate dihydrate is dissolved in anhydrous ethanol, diethanolamine is added, the reaction is carried out, and after post-treatment, zinc oxide quantum dots are obtained. The preparation method can prepare mitochondrial-targeting nanomaterials that achieve precise delivery, controlled release, and visual tracking of HNO into cardiac mitochondria, solving the technical problems of traditional HNO donors' inability to achieve stable loading on a carrier and lack of targeting ability to mitochondria.

The invention discloses gallium ion imprinted amidoxime-based macroporous resin as well as a preparation method and application thereof, and belongs to the technical field of functional polymer materials and separation. The method comprises the following steps: pre-assembling a gallium trichloride template and monomers such as acrylonitrile, generating monodisperse liquid drops by utilizing a microfluidic technology, polymerizing by combining ultraviolet light, eluting the template by hydrochloric acid, and performing amidoximation modification by a hydroxylamine hydrochloride alkaline solution, thereby obtaining the resin. The resin is a monodisperse spherical microsphere, has a macroporous structure, has high selective recognition capability and high adsorption capacity on gallium ions, is fast in adsorption kinetics and good in regeneration performance, and is suitable for selectively separating or enriching gallium ions from a complex solution system.

The invention discloses a substituted benzoxazinone-isoxazoline compound as well as a preparation method and application of the substituted benzoxazinone-isoxazoline compound. The preparation method comprises the following steps: by taking DMF (Dimethyl Formamide) as a solvent, reacting ethyl bromoacetate with a compound (II) to generate a compound (III), performing cyclization in the presence of acetic acid and reduced iron powder to obtain a compound (IV), reacting the compound (IV) with hydroxylamine hydrochloride to generate a compound (V), reacting the compound (V) with NCS and MMA (Methyl Methacrylate) in the presence of TEA (Tetraethyl Ammonium) to generate a compound (VI), and reacting the compound (VI) with NCS and MMA to generate a compound (V). Reacting the compound (VI) with propargyl bromide to obtain a substituted benzoxazinone-isoxazoline compound, performing alkaline hydrolysis on the substituted benzoxazinone-isoxazoline compound, and performing condensation reaction on the substituted benzoxazinone-isoxazoline compound and alcohol or amine to obtain a target product. According to the present invention, the weeding activity test results of the obtained product show that the inhibition effects of the compounds I1, I2, I4, I15 and I16 on the rape are good under the concentration of 100 ppm, the excellent weeding activity is provided, and the good prevention and control effect on the invasive organism zinnia elegans is provided.

The invention discloses a spherical bismuth oxychloride and tin oxide composite material as well as a preparation method and application thereof, and belongs to the field of catalyst technology and electro-catalysis application. According to the spherical bismuth oxychloride and tin oxide composite material, bismuth salt and organic acid serve as raw materials, an organic solvent and hydroxylamine hydrochloride are added under high-speed stirring, then spherical bismuth oxychloride is obtained through a hydrothermal reaction, finally, the spherical bismuth oxychloride and tin salt are physically mixed, and the spherical bismuth oxychloride and tin oxide composite material is obtained. And placing in a muffle furnace for high-temperature calcination to obtain the spherical bismuth oxychloride and tin oxide composite material. The composite material product has extremely high selectivity under an alkaline condition, and high-yield preparation of alkaline hydrogen peroxide is realized by combining a self-made flow type electric reactor. The electrocatalyst prepared by the method disclosed by the invention has extremely high selectivity and high yield for electrocatalytic preparation of hydrogen peroxide, and has a good application prospect in a reaction for realizing on-site in-situ production of hydrogen peroxide.

The invention provides a polyamidoxime uranium adsorbent as well as a preparation method and application thereof, and belongs to the technical field of macromolecular adsorption materials. The preparation method of the polyamidoxime uranium adsorbent comprises the following steps: dispersing polyacrylonitrile microspheres in a water-methanol mixed solvent to obtain a water-methanol solution of the polyacrylonitrile microspheres; dissolving hydroxylamine hydrochloride in water to obtain a hydroxylamine hydrochloride aqueous solution; dropwise adding the alkaline solution into the hydroxylamine hydrochloride aqueous solution, uniformly mixing and stirring, and adding methanol to obtain a free hydroxylamine water-methanol solution; a water-methanol solution of polyacrylonitrile microspheres and a free hydroxylamine water-methanol solution are mixed to obtain a reaction solution, and the polyamidoxime uranium adsorbent is obtained after a heating reaction. Wherein the methanol content in the free hydroxylamine water-methanol solution and the methanol content in the water-methanol solution of the polyacrylonitrile microspheres are the same and are both 16-66 vol%.

The invention provides a synthesis method of 3-chloro-5, 5-dimethyl-4, 5-dihydroisoxazole, which comprises the following steps: mixing isovaleric acid with a catalyst, pumping the mixture and liquid chlorine into a mixer, uniformly mixing, and slowly introducing the mixture into a microchannel for reaction to obtain 2-chloroisovaleric acid; s2, uniformly mixing 2-chloroisovaleric acid in S1 with an acylation reagent, and slowly introducing the mixture into the microchannel for reaction to obtain 3, 3-dimethyl crotonyl chloride; adding hydroxylamine hydrochloride or hydroxylamine sulfate and a solvent into the 3, 3-dimethyl crotonyl chloride in the step S2 in a reaction kettle for dissolving, controlling the temperature of the system to be 0-30 DEG C while stirring, adding alkali in batches, and stirring for reaction to obtain 5, 5-dimethyl-3-isoxazolidinone; and S3, diluting the 5, 5-dimethyl-3-isoxazolidinone obtained in the step S3 and a chlorination reagent with a solvent respectively, and then pumping the diluted 5, 5-dimethyl-3-isoxazolidinone and the chlorination reagent into the microchannel reactor respectively for reaction to obtain the 3-chloro-5, 5-dimethyl-4, 5-dihydroisoxazole. In the production process, tail gas is single in component and convenient to treat, and environmental protection pressure is small; meanwhile, the used main raw materials are bulk and cheap chemicals, so that the production cost is lower.

The invention relates to a synthesis method for improving the mechanical property of amidoxime resin, and belongs to the technical field of new material preparation. The method comprises the following steps: mixing a monomer containing carbon-nitrogen triple bonds, styrene, a dispersing agent, water, an initiator, a pore-foaming agent and a cross-linking agent to obtain a mixed material; sequentially carrying out first heat treatment and second heat treatment on the mixed material in a nitrogen environment to carry out suspension polymerization reaction to obtain an amidoxime resin precursor; mixing the amidoxime resin precursor, hydrazine hydrate and a first solvent to carry out a secondary cross-linking reaction to improve the cross-linking density and mechanical strength of an amidoxime resin skeleton so as to obtain a hydrazine hydrate modified highly-crosslinked precursor; and under a set pH condition, mixing the hydrazine hydrate modified highly-crosslinked precursor, hydroxylamine hydrochloride and a second solvent, and carrying out an amidoxime reaction to obtain the amidoxime resin.

The invention discloses anti-mildew plastic for a packaging container and a preparation method of the anti-mildew plastic, and relates to the technical field of plastic. The plastic is prepared from the modified biochar and the modified polyethylene; wherein 3, 5-diformylphenylboronic acid, 5-nitro-2-(oxiranyl methoxy) acetophenone, ethynyl magnesium bromide, isobutyldichlorosilane, hydroxylamine hydrochloride, ammonium salt and 3-butenyl chloroformate are used for synthesizing an anti-aging substance, then the anti-aging substance and polyethylene are subjected to cross-linking modification, an ultraviolet absorption group, a silicon-carbon bond and a boron-carbon bond are introduced into a polyethylene side chain, and the anti-aging substance is prepared. While the photo-thermal aging of the plastic is prevented, the barrier property of the plastic is improved; the biochar is modified by aminopropyl methyl dimethoxysilane, N, N-diethyl-p-aminobenzaldehyde, 11-chlorodecanoic acid and chitosan, antibacterial groups are generated on the surface of the biochar, and the biochar and modified polyethylene can be stacked in order, so that movement of water vapor and oxygen is prevented, and the anti-mildew effect of the plastic is improved.

This invention belongs to the field of organic chemical synthesis technology, specifically relating to a method for synthesizing 2-fluoro-3-aminobenzoic acid, an important chemical intermediate. Specifically, o-nitroaniline is condensed with hydrated trichloroacetaldehyde and hydroxylamine hydrochloride to obtain 2-(hydroxyimino)-N-(2-nitrophenyl)acetamide; the resulting product undergoes an intramolecular Beckmann rearrangement to generate 7-nitroindigo; 7-nitroindigo undergoes Bayer-Villedge oxidation to generate 2-amino-3-nitrobenzoic acid; 2-amino-3-nitrobenzoic acid undergoes diazotization and halogenation reactions to generate 2-fluoro-3-nitrobenzoic acid or 2-chloro-3-nitrobenzoic acid; 2-fluoro-3-nitrobenzoic acid can be further reduced by nitro to obtain 2-fluoro-3-aminobenzoic acid; or, 2-chloro-3-nitrobenzoic acid can be esterified to obtain 2-chloro-3-nitrobenzoic acid ester, which can then be fluorinated, saponified, and reduced to obtain 2-fluoro-3-aminobenzoic acid. The raw materials of this invention are low in cost and readily available, and the entire reaction route has specific regioselectivity, making it suitable for industrial production.

The invention relates to the technical field of oilfield chemistry, in particular to a reductive dihydroxyl biquaternary ammonium salt, a preparation method thereof and a low-temperature reservoir fracturing fluid assistant.The reductive dihydroxyl biquaternary ammonium salt is prepared according to the following steps that firstly, a needed amount of 2, 3-epoxypropyl trimethyl ammonium chloride is dissolved in water, and a reaction solution is obtained; and 2, introducing nitrogen into the reaction solution to remove oxygen, adding a required amount of diethyl hydroxylamine hydrochloride to obtain a reaction mixed solution, and reacting to obtain an aqueous solution of the reductive dihydroxyl biquaternary ammonium salt. The reductive dihydroxyl biquaternary ammonium salt disclosed by the invention not only has reducibility, but also is a strong polar molecule containing two cations and two hydroxyls, and is small in molecular weight and high in charge density. The low-temperature reservoir fracturing fluid additive prepared from the reductive dihydroxyl biquaternary ammonium salt has dual functions of a low-temperature activator and a clay stabilizer, and can be used for low-temperature reservoir fracturing transformation.

The invention relates to a pre-oxidation coupled coagulation algae removal method, and belongs to the technical field of water treatment.The method comprises the steps that ferrate is added into a water body for pre-oxidation, hydroxylamine hydrochloride is added into the water body after pre-oxidation, algae are flocculated and precipitated, and water-algae separation is achieved; according to the method, the ferrate and the hydroxylamine hydrochloride are combined to treat the algae-containing water body, the ferrate is utilized to pre-oxidize the extracellular organic matters of the algae cells, and by changing the composition of functional groups of the extracellular organic matters, the potential value of the algae liquid is remarkably reduced, and the algae cells are easy to settle. After the ferrate is pre-oxidized, hydroxylamine hydrochloride is added for reduction and stirring reaction, high-valence iron is rapidly reduced and decomposed to generate a large amount of Fe (OH) 3, under the combined action of adsorption, bridging, entrainment and the like, algae cells are agglomerated, flocs are generated and rapidly settled, and the flocs can be directly precipitated and removed from water.