651 results about "Doped graphene" patented technology

The invention discloses an aptamer sensor for detecting a tumor marker through nanochannel confinement electrochemical luminescence and a construction method and application of the aptamer sensor. The aptamer sensor comprises a three-electrode system of an aptamer electrode, a reference electrode and a counter electrode, and an electrolyte solution containing luminol is used as a detection solution; the aptamer electrode is an SNF modified electrode of confined nitrogen-doped graphene quantum dot nano-enzyme, and is obtained by covalently immobilizing a tumor marker aptamer and closing a non-specific site. According to the invention, the gated ECL aptamer sensor of the endogenous co-reactant is constructed based on the SNF confinement N-GQDs nano-enzyme, the ECL signal of a luminol-O2 system is greatly sensitized, and the sensor has the advantages of low detection limit, high sensitivity, wide detection range and the like.

The invention provides a zeolite imidazate framework fluorescent material and a preparation method and application thereof, and belongs to the technical field of detection material preparation and environment. Quantum dots, a molecular imprinting technology and an MOFs material are combined, firstly, Mg and N co-doped graphene quantum dots and ZIF-8 are compounded, then imprinting is carried out on the surface of ZIF-8, and the zeolite imidazate framework fluorescent material based on MOFs is obtained. In the zeolite imidazate framework fluorescent material, Mg and N co-doped graphene quantum dots not only have good fluorescence performance, but also can generate electron transfer with SDZ to form hydrogen-bond-like acting force, imprinted holes similar to a target object in size and shape are reserved in the surface of the imprinted material, and the target object needing to be detected can be selectively recognized; the zeolite imidazate framework fluorescent material can be used for detecting sulfadiazine in the environment and has good practicability.

The invention discloses a self-driven bio-electro-Fenton sewage treatment method based on granular sludge electroactivity domestication. The sewage treatment method comprises the following steps: firstly, inoculating anaerobic granular sludge into an anode chamber of a microbial fuel cell, fixing a clustered carbon fiber electrode in a biological anode chamber as an electrode collector, taking a cathode as an oxygen reduction cathode, and performing electrochemical enrichment to obtain electroactive granular sludge; then, preparing an iron-cobalt diatomic catalyst from the nitrogen-doped graphene oxide, cobalt phthalocyanine and iron phthalocyanine; and finally, adding the iron-cobalt diatomic catalyst into the electroactive granular sludge to form a hybrid structure, controlling dissolved oxygen in a reaction system, and degrading organic pollutants by adopting an SBR (sequencing batch reactor). The biological electro-Fenton technology has a better effect of removing refractory organic pollutants, and compared with a traditional electro-Fenton method, the self-Fenton technology can achieve the activity of molecular oxygen without external electric energy input.

The invention discloses an electrochemical luminescence immunosensor with low trigger potential and a construction method and application thereof, the sensor comprises a three-electrode system of an immune electrode, a reference electrode and a counter electrode, and when the electrochemical luminescence immunosensor is used, a detection solution comprises luminol and hydrogen peroxide; the immunoelectrode is an SNF modified electrode confined with metal palladium nanoparticles and nitrogen-doped graphene quantum dots, immunoglobulin A of immunospheres is covalently immobilized, then a primary antibody of a directionally immobilized tumor marker is constructed, and non-specific sites are closed, so that the immunoelectrode is obtained. The independent nano channel of the SNF film effectively avoids agglomeration of a confinement material, and the in-situ deposition mode is efficient and rapid; the good biocompatibility of the SNF provides a high-quality platform for the preparation of an immunosensing interface. The prepared immunosensor has the advantages of fast response speed, high ECL signal and good selective anti-interference capability, and has potential application prospects in tumor marker analysis and detection.

The invention discloses an anti-corrosion fireproof coating applied to a new energy battery box and a preparation method, and relates to the technical field of industrial coatings, the anti-corrosion fireproof coating comprises the following specific components: a base resin system, a curing agent, a functional filler system, a flame retardant system, a solvent system and an auxiliary agent system; the anticorrosive and fireproof coating further comprises additives, wherein the additives specifically comprise a functionalized MXene loaded lithium ion adsorbent, a metal organic framework encapsulated quaternary phosphonium salt, polyaryletherketone coated antimony trioxide nano-particles and boron-nitrogen co-doped graphene aerogel powder; the material is prepared based on the materials. According to the invention, multiple additives are synergistically introduced into a traditional basic coating system, and on the basis of a basic flame-retardant and anti-corrosion structure, lithium ion directional adsorption, gas-phase free radical active intervention, high-temperature carbonization barrier construction and three-dimensional thermal barrier network configuration are further realized; therefore, the multi-dimensional safety performance of the coating in battery thermal runaway, salt spray corrosion and high-temperature impact environments is remarkably improved.

The invention relates to a dual-rare earth metal catalytic nano material, a diaphragm and a preparation method and application thereof. The preparation method comprises the following steps: carrying out hydrothermal reaction on an aqueous solution containing a carbon source, a hard template, a graphene oxide dispersion liquid, a nitrogen source, a phosphorus source, cerium salt and neodymium salt; then carrying out centrifugal separation to obtain a precipitate, and generating a precursor containing Ce and Nd rare earth bimetallic modified nitrogen and phosphorus doped graphene coated microspheres; and carrying out chemical etching on the precipitate after heat treatment to obtain the dual-rare earth metal catalytic nano material (HCS-coated NPrGO / CeNd). The HCS-coated NPrGO / CeNd can be used as a modification material of a lithium-sulfur battery diaphragm, not only can catalyze the conversion of polysulfide, but also can inhibit the shuttle effect of the polysulfide, so that the lithium-sulfur battery has relatively high capacity under high-rate charge and discharge, and has relatively low capacity fading rate in a high-rate long-cycle test.

The invention provides a composite lithium ion battery diaphragm. The composite lithium ion battery diaphragm is composed of rare earth doped graphene and polyimide. According to the invention, the problem that the existing composite lithium ion battery diaphragm is insufficient in conductivity, dendritic crystal inhibition, stability in long-term use under extreme conditions and the like is solved, and the preparation of the lithium ion battery diaphragm capable of keeping high ionic conductivity, mechanical strength, thermal stability and dendritic crystal inhibition is realized. Experiments prove that the ionic conductivity of the cerium nitrate doped graphene-polyimide composite lithium ion battery diaphragm obtained by the invention is 0.5-1.8 mS / cm; the mechanical strength is 50 to 79 MPa; the thermal shrinkage rate in thermal stability is less than or equal to 5%-12% (150 DEG C / 1h); and the cycle life of a dendritic crystal inhibition test is more than 80-200 times (1mA / cm).

The invention relates to the technical field of electrode paste, in particular to electrode paste for a submerged arc furnace and a preparation method of the electrode paste. Comprising three-level grain size distribution anthracite aggregate which is electrically calcined at high temperature and modified by a KH-550 silane coupling agent, a modified silicon carbide whisker and boron-doped graphene-like carbon nitride composite filler, a maleic anhydride-mediated compatible medium-temperature pitch-polyborosiloxane binder and a graphite powder-borax functional additive. A step-by-step mixing and two-stage sintering process is adopted in the preparation process, a covalent bond interface bridging structure is constructed through the coupling agent, the composite dispersing agent regulates and controls the multi-dimensional network distribution of the filler, and the process synergistically improves the compactness and the interface bonding force of the green body. The electrode paste is firm in interface bonding, can form a ceramic protective phase at a high temperature, has excellent conductivity and mechanical strength, and prolongs the service life of the electrode paste for the submerged arc furnace.

The invention relates to the field of catalysts, in particular to a preparation method and application of an alumina-loaded copper-doped graphene-like catalyst, and the preparation method comprises the following steps: step 1, dispersing biomass in deionized water to form a suspension A; step 2, adding an aluminum salt and an iron salt into the turbid liquid A to form a turbid liquid B; step 3, adding a nitrogen source into the turbid liquid B to form impregnation liquid C; step 4, pouring the steeping liquor C into a beaker filled with alumina pellets, and drying to obtain dried pellets; and 5, roasting the dried pellets in a tubular furnace, cooling to room temperature, repeatedly washing with water, and drying to obtain the catalyst. The catalyst disclosed by the invention can be used for rapidly degrading refractory organic pollutants in water within 30 minutes under the synergism of microorganisms. The catalyst provided by the invention has good stability in the process of removing organic pollutants, and almost no metal ions are released.

The present invention combines a fluorescence sensor with an array to provide a fluorescence sensing array detection platform and a detection method for multiple plasticizers. The fluorescence sensing array detection platform includes a B-doped graphene quantum dot solution using N,N-dimethylformamide as a solvent and a B-GQDs solution using cyclohexane as a solvent; the fluorescence intensity of the B-GQDs solution with DMF as the solvent at the fluorescence characteristic peak obtained under ultraviolet light excitation at a wavelength of 350 nm, and the fluorescence data at 391 nm, 413 nm, and 434 nm are used as array points 1, 2, and 3; the fluorescence intensity of the B-GQDs solution with CH as the solvent at the fluorescence characteristic peak obtained under ultraviolet light excitation at a wavelength of 350 nm, and the fluorescence data at 386 nm, 408 nm, and 430 nm are used as array points 4, 5, and 6; thus, a 3×2 fluorescence sensor array is constructed. The detection method using the fluorescence sensor array of the present invention has simple steps, and has satisfactory specificity, reproducibility, stability and practicability, and has application potential.

The invention relates to a method for preparing porous carbon based on synchronous synthesis of nitrile resin / graphene nanosheets and a porous carbon material, synthesis of nitrile resin and dispersion of graphene nanosheets are synchronously realized by means of a ball milling process, the synthesized nitrile resin is used as a carbon source, the graphene nanosheets are used as conductive reinforcements, and the porous carbon material is prepared. According to a certain component proportion, the nitrile resin doped graphene nanosheet porous carbon is prepared according to a certain heat treatment procedure. Based on synchronous synthesis of the nitrile resin / graphene nanosheets, functionalized utilization of nitrile resin and graphene is realized; the high carbon yield of the nitrile resin and the high conductivity of the graphene are utilized to improve the electrochemical performance of the prepared porous carbon. The obtained nitrile resin / graphene porous carbon has excellent electrochemical performance, is synthesized in one pot, not only integrates and optimizes the technological process, but also has the effect of '1 + 1 > 2', and has industrial application prospects.

According to the cobalt-doped molybdenum disulfide lithium-sulfur battery composite positive electrode material, the preparation method and the application, a cobalt-doped stable molybdenum disulfide defect structure composite nitrogen-doped graphene material is prepared by combining a solvothermal method and an annealing technology, and the process is mature; the method is simple, and the composite positive electrode material with high sulfur content is easy to obtain. According to the lithium-sulfur battery composite sulfur positive electrode material disclosed by the invention, the strong chemical adsorption effect and catalytic conversion effect of the cobalt-doped stable molybdenum disulfide defect structure composite nitrogen-doped graphene carrier on polar lithium polysulfide are utilized, so that the diffusion of the lithium polysulfide in an ether electrolyte is inhibited, and the electrochemical reaction kinetics is improved; therefore, the shuttling effect is slowed down, and the lithium-sulfur battery has the characteristics of high capacity and long service life.

The invention discloses a hydrophilic graphene dispersion liquid for PCB hole metallization, and belongs to the technical field of circuit board processing, the hydrophilic graphene dispersion liquid comprises the following components by mass: 1-5% of boron-doped graphene, 1-5% of boron-doped graphene quantum dots, 10-40% of polypyrrole, 0.5-1% of a dispersant, and 0.5-2% of a surfactant. The second purpose of the invention is to provide a preparation method of the hydrophilic graphene dispersion liquid for PCB hole metallization, the dispersion liquid is subjected to boron doping treatment on graphene and graphene quantum dots, so that the overall conductivity is enhanced, the hydrophilicity is enhanced, the dispersion liquid has excellent dispersity, and the hydrophilicity of the dispersion liquid is improved. Through the synergistic effect of polypyrrole, boron-doped graphene and boron-doped graphene quantum dots, the stability and adhesion of the composite material are further enhanced.

The invention discloses a double-channel gold-copper-doped graphene electrochemical immunosensor as well as a preparation method and application thereof. The double-channel gold-copper-doped graphene electrochemical immunosensor comprises a gold / gold-copper co-doped vertical graphene electrode, and bovine serum albumin and an antibody which are incubated on the gold / gold-copper co-doped vertical graphene electrode, the gold / gold-copper co-doped vertical graphene electrode comprises a gold-copper co-doped vertical graphene electrode and gold nanoparticles loaded on the surface of the gold-copper co-doped vertical graphene electrode, and the gold-copper co-doped vertical graphene electrode comprises a substrate and a gold-copper co-doped vertical graphene nanosheet grown on the surface of the substrate. The sensor capable of sensitively detecting the concentration of the carcinoembryonic antigen secreted by the tumor cells is prepared, an immunoreaction detection system is built, a reliable industrial signal amplification platform is provided for early diagnosis of tumors, and a new strategy is developed for research of tumor cytology.

The invention belongs to the technical field of graphene film preparation, and particularly relates to a graphene thick film preparation method, which comprises: mixing a boric acid aqueous solution and a graphene oxide dispersion liquid to obtain a boric acid / graphene oxide mixed dispersion liquid; after the mixed dispersion liquid of boric acid / graphene oxide is coated, a solvent is evaporated, and a boric acid doped graphene oxide film is prepared; and stacking a plurality of layers of boric acid doped graphene oxide films, performing pressurization treatment, and performing annealing treatment in an inert atmosphere to obtain the graphene thick film. The preparation method provided by the invention not only solves the problem of film interface effect of the graphene thick film in the prior art and remarkably improves the conductivity of the graphene thick film, but also realizes effective regulation and control of the thickness of the graphene thick film through a simple stacking mode, and the preparation method is suitable for large-scale production. Powerful support is provided for application of the graphene thick film in the fields of electrochemical energy storage, electromagnetic shielding, heat dissipation and electric conduction.

The invention relates to the technical field of capacitors, and discloses a high-energy-density capacitor which is characterized in that a positive electrode is composed of a composite active material, a conductive agent and a binder, the composite active material comprises a mixture of nitrogen-sulfur co-doped carbon foam magnetic microspheres and iron sesquioxide nanodot at nitrogen-doped graphene, and the conductive agent is a mixture of nitrogen-sulfur co-doped carbon foam magnetic microspheres and iron sesquioxide nanodot at nitrogen-doped graphene. The preparation method of the nitrogen-sulfur co-doped carbon foam magnetic microspheres comprises the following steps: by taking polyacrylonitrile as a carbon source, thiourea as a sulfur source and ferric nitrate as an iron source, carrying out hydrothermal reaction and then carrying out carbonization treatment at 800-1000 DEG C for 2-4 hours; the energy density of the high-energy-density capacitor can reach 700-800 Wh / kg, the power density is larger than or equal to 10 kW / kg, compared with a traditional super capacitor, the high-energy-density capacitor has the advantages that the energy density is remarkably improved, and the application requirements of the fields with high requirements for energy and power such as electric automobiles and intelligent power grids can be met.

A boron-doped graphene composite solid-state electrolyte and its preparation and application. A mixed solution of polyacrylonitrile (PAN) and N,N-dimethylformamide is prepared into a PAN porous film using electrospinning technology. A PEO casting solution is prepared by mixing boron-doped graphene, polyethylene oxide, lithium bis(trifluoromethanesulfonylimide), and acetonitrile. This solution is then cast onto the PAN porous film and, after vacuum drying, forms a composite solid-state electrolyte with polyacrylonitrile fibers as a support, polyethylene oxide as a matrix, and boron-doped graphene as a filler. The composite solid-state electrolyte prepared by the present invention has high ionic conductivity and lithium ion transference number, providing lithium batteries with good rate performance and cycle stability.

The invention discloses a double transition metal doped graphene catalyst and application thereof, the double transition metal doped graphene catalyst is of a hexagonal crystal system structure, and the space group is P6 / mmm; the composition form of the active center is Cu2C3N3, Nb2C3N3, Ta2C3N3, Rh2C6, Rh2C3N3 and Rh2N6, the hydrogen evolution free energy of the active center is-0.03 eV,-0.09 eV, 0.10 eV, 0.12 eV,-0.21 eV and 0.06 eV respectively, the metal binding energy of the active center is-4.53 eV,-8.60 eV,-8.03 eV,-6.13 eV,-7.11 eV and-5.62 eV respectively, the metal forming energy of the active center is-0.54 eV,-1.94 eV,-0.06 eV,-0.64 eV,-1.62 eV and-0.13 eV respectively, and the active center has good catalytic activity, structural stability and preparation feasibility and is used for

The invention discloses a preparation method of an N-doped graphene-coated silicon-based negative electrode material, which comprises the following steps of: performing carbon coating by using graphene, controlling the particle size of a silicon substrate to be less than 2 microns, and realizing micro-nanocrystallization of a silicon main body material through mechanical ball milling, so that the micro-nanocrystallization silicon material is distributed in a graphite layer while metal-doped silicon monoxide obtains a smaller particle size; according to the preparation method, metal doped silicon monoxide is taken as a silicon source, the surface of the metal doped silicon monoxide is coated with the stripped graphene, the metal doped silicon monoxide is coated with the graphene oxide, finally, a silicon material is further uniformly coated with graphene micro-nanosheets by adopting a rapid spray drying technology, and an electroactive substance is effectively protected from being influenced by volume change caused in the charging and discharging process through the synergistic effect of the graphene micro-nanosheets. The preparation method has the advantages that after the composite material is prepared from micron-sized silicon monoxide and graphene, low-cost preparation of the modified silicon monoxide is realized, the electrode material with excellent electrochemical performance is obtained, the stability of the composite material is effectively improved, the cycle service life is prolonged, and the application and popularization value is relatively good.

The invention relates to the field of photoelectrocatalytic materials, and discloses a photoelectrocatalytic material and a preparation method and application thereof.The photoelectrocatalytic material is formed by a bismuth molybdenum oxide and nickel-doped cobalt oxide heterostructure, the surface plasma resonance effect of gold nanoparticles and a conductive network of nitrogen-doped graphene and carbon quantum dots are combined, and a graded micro-nano structure is constructed; according to the present invention, the material has characteristics of high light current density, low charge transfer resistance and excellent catalytic activity and long-term stability in liquid-phase degradation and gas-phase oxidation through the built-in electric field and the optimization of the conductive network, such that the material has characteristics of high light current density and low charge transfer resistance, and can be used in liquid-phase degradation and gas-phase oxidation. The material is widely applicable to the fields of pollutant degradation, gas conversion, water photoelectrolysis and the like, and an efficient solution is provided for innovative development of a photocatalysis technology.

The invention discloses a method for preparing a polyphenylene sulfide-based membrane electrode in situ, which comprises the following steps: carrying out plasma treatment on polyphenylene sulfide cloth, soaking the polyphenylene sulfide cloth in an acid solution or an alkaline solution, cleaning and drying to obtain a hydrophilic polyphenylene sulfide membrane; then, a layer of PAN or PVP solution doped with rare earth ions or iron element ions is poured on the surface of the hydrophilic polyphenylene sulfide diaphragm, and after drying, the composite polyphenylene sulfide diaphragm is obtained; and performing laser engraving on the PAN or PVP polymer layer containing rare earth ions or iron-series element ions in the composite polyphenylene sulfide diaphragm by utilizing carbon dioxide laser engraving to form rare earth ion or iron-series element ion doped graphene, thereby obtaining the polyphenylene sulfide-based membrane electrode for alkaline electrolyzed water. The method has the advantages of low requirement on temperature, simplicity, feasibility, safety, controllability and low energy consumption, the electrode material is generated on the surface of the membrane in situ, and the possibility that the electrode falls off in the later use process is reduced.

The present invention relates to the technical field of high thermal insulation carbon materials and provides a carbon fiber-doped graphene oxide foam material, a preparation method therefor, and a use thereof. In the present invention, graphene oxide and carbon fibers are composited in a hydrothermal synthesis manner, the resulting composite is processed into a composite aerogel in a freeze drying manner, and the composite aerogel is carbonized and graphitized to prepare the carbon fiber-doped graphene oxide foam material. The carbon fiber-doped graphene oxide foam material of the present invention can resist a high temperature of 2000-3000℃. The carbon fiber-doped graphene oxide foam material has a heat conductivity coefficient of 0.16-0.27 W / m·K and a porosity of 85-95%. The carbon fiber-doped graphene oxide foam material has excellent high-temperature resistance and stability, and maintains good mechanical properties and structural strength while improving the heat insulation performance.

The invention belongs to the technical field of new energy batteries, and particularly relates to a fluorine-doped graphdiyne material and a preparation method and application thereof. The preparation method of the fluorine-doped graphdiyne material comprises the following steps: in a solvent system, mixing graphdiyne and a solid fluorine source, and drying to obtain a composite precursor; under the protective atmosphere, the composite precursor is annealed, so that the fluorine source is decomposed to release hydrogen fluoride and fluorine free radicals, the hydrogen fluoride or the fluorine free radicals are combined with carbon sites on graphdiyne through nucleophilic substitution, C-F bonds are formed, and the fluorine-doped graphdiyne material is obtained; the mass ratio of graphdiyne to the solid fluorine source is 30: (1-4). The fluorine-doped graphdiyne has the advantages that the defects are increased, the disorder is reduced, and the lithium storage capacity of the graphdiyne is improved, so that the long-term cycle performance and the high-rate performance are improved.

The invention discloses a copper-rich phase high-entropy alloy and application thereof in urea synthesis, and belongs to the technical field of electro-catalysis. According to the method, serine and histidine functionalized and boron-doped graphene quantum dots (SHB-GQD) and a copper-rich phase are introduced, so that the urea synthesis electro-catalytic performance of the MnFeCoNiCu2.0 high-entropy alloy (MnFeCoNiCu2.0 HEA / SHB-GQD) is improved; the method disclosed by the invention is green and environment-friendly, simple and easy to implement and relatively low in cost, and shows excellent electrocatalytic activity and high stability. According to the MnFeCoNiCu2. 0HEA / SHB-GQD urea prepared by the preparation method disclosed by the invention, the synthesis rate reaches 59.01 mmol gcatalyst <-1 > h <-1 >; the Faraday efficiency reaches 26.6%; and the influence on the urea synthesis yield and the Faraday efficiency is small after the catalyst is recycled for 8 times.

The invention discloses a method for screening a high-catalytic-activity nitrogen-doped graphene-loaded single-metal-atom ammonia synthesis catalyst, and belongs to the technical field of ammonia synthesis. The method comprises the following steps: constructing an original graphene configuration; constructing a nitrogen-doped graphene configuration; a nitrogen-doped graphene loaded monometal configuration is constructed; the Eform is formed to judge the stability; constructing an adsorption configuration of reactant molecules; analyzing the relaxation configuration to judge the activation degree; the adsorption stability is judged according to the adsorption energy Eads; determining a path of N2 thermal reduction reaction; adopting NEB and Dimer methods to construct a transition state spatial configuration; reaction heat and activation energy are calculated, and activity differences of different catalyst surfaces are analyzed. Based on density functional theory calculation, catalyst screening standards with formation energy, adsorption energy and activation energy barriers as indexes are established, the high-activity catalyst is screened out theoretically, the experiment trial and error cost is reduced, and the catalyst development efficiency is improved.

A method of forming a graphene device includes: providing a glass substrate with a blocking layer disposed thereon to form a stack; providing a first electrode and a second electrode; increasing the temperature of the stack to at least 100° C.; applying an external electric field (VP) to the first electrode such that at least one metal ion of the glass substrate migrates toward the first electrode to create a depletion region in the glass substrate adjacent the second electrode; decreasing the temperature of the stack to room temperature while applying the external electric field to the first electrode; and after reaching room temperature, setting the external electric field to zero to create a frozen voltage region adjacent the second electrode.

The invention provides a crystalline silicon solar cell with high conversion efficiency and a preparation process thereof, and belongs to the technical field of solar cell preparation. The preparation process comprises the following steps: pretreating a crystal silicon wafer; preparing a bionic micro-nano composite film; preparing a composite structure on the surface of the silicon wafer; preparing the glass powder doped with the phosphorus-doped graphene; preparing a positive electrode conductive slurry; and preparing the crystalline silicon solar cell. The CuS nanocrystals / quantum dots are deposited on the surface of the bionic micro-nano composite film, the effects of antireflection, passivation and sensitization of the silicon wafer can be achieved, the photoelectric conversion efficiency of the battery is further improved, the CuS nanocrystals / quantum dots are deposited, the absorption range of the silicon wafer to the optical wavelength can be increased, and the photoelectric conversion efficiency of the battery is improved. Meanwhile, one absorbed photon can be converted into a plurality of photon-generated carriers through the CuS quantum effect, and the photoelectric conversion efficiency of the cell is improved.

The invention provides a method for preparing a 4, 4 '-biphenol compound by an electrochemical method, which is characterized in that in a diaphragm-free electrolytic bath, a phenol compound and a salt solution thereof are used as raw materials, a boron-phosphorus doped graphene electrode is used as an anode electrode, and an electrolytic reaction is carried out to generate the 4, 4'-biphenol compound. According to the method provided by the invention, the para-coupled product 4, 4 '-biphenol compound can be obtained with high selectivity through electrochemical phenol oxidative coupling, the selectivity is high, only trace electrolyte salt is used in the whole process, and basically no three wastes are generated. Compared with the traditional catalytic reaction, the method has the advantages of open reaction, mild reaction conditions, no generation of isomerized products, great shortening of the separation and purification process, and very good industrial application scenario.

The invention relates to a nano composite photosensitizer for transepithelial iontophoresis corneal collagen crosslinking and a preparation method and application of the nano composite photosensitizer, and the prepared nitrogen-sulfur co-doped graphene quantum dot has the characteristics of small particle size, negative potential, high electron transfer efficiency, high optical excitation ROS efficiency and the like, is an excellent nano carrier of riboflavin sodium phosphate, and can be used for preparing the nano composite photosensitizer. The nano composite photosensitizer prepared by modifying riboflavin with nitrogen and sulfur co-doped graphene quantum dots has high electric field responsiveness, high corneal riboflavin infiltration capacity, high ROS generation efficiency and good biocompatibility; according to the invention, nitrogen-sulfur co-doped graphene quantum dots are synthesized by a simple hydrothermal method, and then the nitrogen-sulfur co-doped graphene quantum dot modified riboflavin nano-composite photosensitizer is synthesized by a one-step esterification reaction. The method is simple, environment-friendly and safe to operate, low in cost and beneficial to industrialization and entering a clinical test stage; according to the invention, the nano-composite photosensitizer of riboflavin modified by nitrogen and sulfur co-doped graphene quantum dots is creatively applied to a cross-epithelial iontophoresis cornea collagen cross-linking technique. By using the composite photosensitizer, the matrix riboflavin content similar to that of an epithelium-removed standard group can be realized; the biomechanical property slightly better than that of a gold standard group is realized; and compared with a gold standard operation, the advantages of epithelium retention and short penetration time are realized. The research result certainly provides a new insight for treatment in the field of keratoconus.

The present invention discloses a sulfur-nitrogen co-doped graphene hollow nanosphere and its preparation and application, belonging to the technical field of graphene nanomaterials. During the preparation, a mixture of thiourea and zinc powder is first calcined under the protection of an inert gas, and then H2O and HCl are added to the calcined product and heated for reaction, followed by post-processing to obtain the target product. The resulting product is a sulfur-nitrogen co-doped graphene material, which presents a hollow spherical morphology. This material has a large specific surface area and pore volume, and both the nitrogen and sulfur doping amounts have reached a high level. It has been verified that the obtained high-sulfur-nitrogen co-doped graphene hollow nanospheres have unique graphite nitrogen-pyridine nitrogen-thiophene sulfur synergistic active sites, which have high atomic utilization and high stability, and exhibit the best performance of activating persulfate to degrade organic matter. It can continuously and rapidly separate organic pollutants in actual water bodies and exhibit excellent stability.