This invention relates to the field of intelligent
brain disease diagnosis technology, specifically providing an auxiliary diagnostic method and
system based on multimodal decoupled dynamic graph learning. The method includes: acquiring and preprocessing
multimodal data (such as
neuroimaging, genetic markers, etc.) of the subject; extracting common
pathological information and modality-specific features through a shared
encoder and modality-specific encoders respectively, and optimizing the
separation process using a decoupling
loss function; furthermore, fusing all modality embeddings using a multi-head self-attention mechanism with a masked matrix to generate initial node representations, where the
mask is used to suppress modality self-attention; subsequently, performing hierarchical dynamic graph
convolution based on the node representations: in each layer, dynamically updating the graph
adjacency matrix by combining the current node representation with the original features, and iteratively optimizing the node representations through
message passing; finally, inputting the optimized representations into a classifier to obtain
disease prediction results. This invention improves the
automation performance and reliability of diagnosis.