Production equipment and a method of a self-adhesive layer band. A base material is treated by a base material unfolding machine, a head-tail-overlapping machine, a base material buffering adjusting bracket and a base material dryer successively, enters into a gluing pool for gluing, then enters a dryer for drying; the dried base material is rolled with an isolated film on a surface thereof by a mulch applicator, cooled by a self-adhesive layer buffering adjusting bracket and adjusted by an automatic error correcting controller; then the base material can be packaged by a product winder and finally cut into dimensions required by production specifications by a cutting machine. After gluing, the base material is dried and returns to the gluing pool for a second gluing; and base material enters into the dryer again for drying after the second gluing, so as to increase peeling intensity of a self-adhesive waterproof coiled material and bonding strength of the material with a base, accelerate drying speed and increase product quality. According to the invention, base material treatment, gluing, drying, coating, cooling, rolling and packaging can be finished in a line, so as to realizeflexible operation, high degree of automation and good product quality.