237 results about "Nitrogenous heterocyclic compound" patented technology

A salt of a substituted amino six-membered nitric heterocyclic compound, a crystal form thereof, a method for preparing same, and use thereof are provided. A dihydrochloride salt of a compound represented by formula (I) is a specific example. The salt can be prepared as a crystal form, the crystal form preferably having the following advantages: good solubility, low hygroscopicity, stable quality, and crystal form stability, thus being more easily developed into drugs as compared with the compound represented by formula (I) or other salts.

The present invention discloses a non-aqueous electrolyte for a secondary battery and a secondary battery thereof, the electrolyte comprises an electrolyte salt, a non-aqueous solvent and an additive, the additive at least comprises: a nitrogen-containing heterocyclic compound as a first additive, a film-forming additive with a film-forming potential of less than 1.5 V (vs. Li + / Li) as a second additive, the specific structure of the additive is shown in the specification. The nitrogen-containing heterocyclic compound and the film-forming additive with the film-forming potential lower than 1.5 V (vs.Li < + > / Li) are combined for use, and the nitrogen-containing heterocyclic compound and the film-forming additive are regulated in a specific content ratio range to fully generate a synergistic effect, so that water catching and acid inhibition can be effectively realized, decomposition and gas production can be effectively inhibited at high temperature and high voltage, the stability of the electrolyte is greatly improved, and the service life of the electrolyte is prolonged. And an SEI film with excellent ion transmission capability and structure / thermal stability can be formed on the surface of the electrode, so that the first efficiency of the battery is effectively improved, and the low-temperature performance and the cycle performance of the battery are further improved.

The invention relates to a nitrogen-containing heterocyclic compound as well as a preparation method and application thereof, belongs to the technical field of heterocyclic compound synthesis, and solves the problems of low reaction efficiency and high energy consumption caused by the fact that an existing method for synthesizing an indole maleimide derivative needs to be carried out step by step. The preparation method comprises the following steps: step 1, adding indoleacetamide and a nucleophilic reagent into a mixed solution, and reacting; 2, performing post-treatment to obtain a nitrogen-containing heterocyclic compound; the mixed solution comprises alkali, an additive and an organic solvent; the alkali comprises one of triethylamine (Et3N), N, N-diisopropylethylamine, pyridine and 1, 8-diazabicyclo [5.4. 0] undec-7-ene, and the alkali comprises one of 1, 8-diazabicyclo [5.4. 0] undec-7-ene.

The invention belongs to the field of alkyd resin, and particularly relates to alkyd resin with high adhesive force and a preparation method thereof. The high-adhesion alkyd resin is prepared from soya oil acid, a nitrogen-containing heterocyclic compound, phthalic anhydride, pentaerythritol and hydroxyl-terminated polydimethylsiloxane. By introducing a nitrogen-containing heterocyclic compound (such as quinoline and triazole) and hydroxyl-terminated polydimethylsiloxane (PDMS), the molecular structure of the alkyd resin is remarkably optimized, so that the alkyd resin is superior to the traditional alkyd resin in the aspects of heat resistance, corrosion resistance, mechanical strength, adhesive force, construction performance and the like. The coating is suitable for the fields of high-temperature anticorrosive coatings, marine coatings, industrial protective coatings and the like, and shows remarkable technical advantages and wide market prospects.

The invention belongs to the technical field of photoelectric materials, and relates to a nitrogen-containing heterocyclic compound and an organic electroluminescent element containing the nitrogen-containing heterocyclic compound. The compound has a structure represented by formula (1): wherein L is selected from a single bond, a substituted or unsubstituted C6-C60 arylene group, and a substituted or unsubstituted C3-C60 heteroarylene group, o is an integer from 1 to 3, and when o is 2 or greater, L are the same as or different from each other. The organic electroluminescent element prepared from the compound has higher current efficiency and longer service life, and can be used as an N-type charge generation layer material for preparing the organic electroluminescent element.

The invention relates to a porous aromatic ion framework material as well as a preparation method and application thereof in iodine adsorption. The structural formula is shown as a formula (I) or a formula (II), an organic monomer with electronegativity and a triazine nitrogen-containing heterocyclic compound are adopted as construction elements, the porous aromatic ion framework material is prepared through Friedel-Crafts alkylation reaction self-polymerization or copolymerization, and tedious steps such as post-modification are avoided. A large number of benzene rings exist in the polymer, an ion skeleton provides rich active sites, and the material can rapidly adsorb steam iodine and iodine elementary substances in a solution in a large amount. The porous aromatic ion framework material prepared by the invention has excellent stability, can be used as a novel solid adsorbent to capture elemental iodine from a severe environment, is easy to recover, can be recycled, and has a good application prospect in the practical application of iodine capture.

The invention belongs to the technical field of pest control, and discloses application of a nitrogen-containing heterocyclic compound in control of ampullaria gigas. According to the invention, a nitrogen-containing heterocyclic compound with the activity of killing ampullaria gigas is screened by taking ampullaria gigas arginine kinase as an action target, and the nitrogen-containing heterocyclic compound is N-[4-(3, 5-diphenyl-4, 5-dihydro-1H-pyrazole-1-yl) benzyl]-N-(1-hexyl-1H-benzimidazole-2-yl) amine. The nitrogen-containing heterocyclic compound is used as an active component to be prepared into a suspending agent or a granule, the suspending agent or the granule has an excellent killing effect on ampullaria gigas, and compared with an existing arginine kinase inhibitor quercetin, the nitrogen-containing heterocyclic compound is higher in activity, good in selectivity, low in toxicity to vertebrates and huge in application potential.

The disclosure relates to compounds of the disclosure and pharmaceutically acceptable salts thereof to their use in medicine; to compositions containing them; to processes for their preparation; and to intermediates used in such processes. The compounds of the disclosure may be useful in the treatment, prevention, suppression and amelioration of disease(s) such as atopic dermatitis, eosinophilic gastritis, atopic keratoconjunctivitis, allergy, alopecia, Alzheimer's disease, asthma, atherosclerosis, Bechet's disease, bullous pemphigoid, cancer, chronic obstructive pulmonary disease, chronic pruritis, chronic urticaria, Crohn's disease (CD), dermatitis, diabetic kidney disease, eosinophilic esophagitis, fungal keratitis, gout, idiopathic pulmonary fibrosis (IPF), keloids, non-alcoholic steatohepatitis (NASH), primary biliary cirrhosis, prurigo nodularis, psoriasis, psoriatic arthritis, rhinosinusitis, scleroderma, systemic lupus erythematosus (SLE), systemic sclerosis, ulcerative colitis (UC), vitiligo, or hidradenitis suppurativa. The compounds of the disclosure may be useful in the treatment, prevention, suppression and amelioration of a dermatological condition or a respiratory condition.

The invention belongs to the technical field of antibacterial medicines, and particularly relates to a heliotropin-modified ruthenium polypyridine complex as well as a preparation method and application thereof. The structural formula of the ruthenium polypyridine complex is shown as a formula I. According to the polypyridine ruthenium complex modified by the heliotropin structure, the bacterial cell membrane penetrating capacity and the retention effect of the polypyridine ruthenium complex are enhanced. As the ruthenium complex has a rigid octahedral geometric structure, the structure is easier to modify, so that the ruthenium complex can more easily optimize the binding affinity of cell targets compared with organic drugs; the polypyridine structure is a typical nitrogen-containing heterocyclic compound, so that the polypyridine structure has more target spots, and can be used for breaking bacterial cell membranes, thereby inhibiting the generation of bacterial toxins; and the formula I of the # imgabs0 # is shown in the specification.

Provided is a low-molecular compound or a salt thereof, or a solvate thereof which has the ability to activate Nrf2.The present invention provides a compound represented by the formula (1) or a salt thereof, or a solvate thereof, wherein Xa1 is CRa1 or N, Xa3 is CRa3 or N, Ra1, Ra2 and Ra3 are each independently selected from the group consisting of hydrogen, halogen and C1-C6 alkoxy, Xb1, Xb2 and Xb3 are each independently selected from the group consisting of CH2, O, NH, S and C═O, Y is C6-C10 aryl optionally having a substituent or 5- to 10-membered heteroaryl optionally having a substituent, and Z is C6-C10 aryl optionally having a substituent, 5- to 10-membered heteroaryl optionally having a substituent or C1-C6 alkyl optionally having a substituent.

The invention belongs to the field of oligonucleotide synthesis, and particularly relates to a polymer-loaded glass carrier, a preparation method and application thereof, and an oligonucleotide synthesis method. The polymer-loaded glass carrier comprises a glass carrier and a modified styrene / nitrogen-containing heterocyclic ring copolymer coating the surface of the glass carrier, the ratio of the thickness of the modified styrene / nitrogen-containing heterocyclic ring copolymer to the average pore size of the glass carrier is 1: (200-250), and the modified styrene / nitrogen-containing heterocyclic ring copolymer has a structure as shown in a formula (1). The preparation method is characterized in that a nitrogen-containing heterocyclic ring is introduced into a polystyrene molecular chain and coupled to CPG, and meanwhile, the ratio of the thickness of the modified styrene / nitrogen-containing heterocyclic ring copolymer to the average pore size of CPG is strictly controlled, so that the effective load of nucleotide can be effectively improved; meanwhile, compared with the method that a nitrogen-containing heterocyclic compound is independently introduced into an oligonucleotide synthesis system, the synthesis efficiency and purity of nucleic acid can be remarkably improved. # imgabs0 #

The application discloses a preparation method of a nitrogen-containing heterocyclic compound and an alkali metal salt of the nitrogen-containing heterocyclic compound, and steps of the preparation method of the nitrogen-containing heterocyclic compound comprise: (1) uniformly mixing trithiocyanic acid with a first solvent, introducing sulfuryl fluoride gas or adding an alkenyl sulfonyl fluoride to perform a reaction, and obtaining a crude product through a crude treatment after the reaction is finished; (2) purifying the crude product to obtain the nitrogen-containing heterocyclic compound shown in a structural formula 1; wherein R1, R2 and R3 are each independently selected from -H, -SO2F or -CH2-(CH2) n -SO2F, n is an integer selected from 1-10, and R1, R2 and R3 are not H at the same time. The preparation method of the nitrogen-containing heterocyclic compound and the alkali metal salt of the nitrogen-containing heterocyclic compound can be applied to a large amount of trithiocyanic acid in a lithium battery electrolyte, raw materials are easy to obtain, operation is simple, the yield is high, the condition is mild, the requirement for equipment is low, and the method is suitable for industrial production.

Provided are: a composition for chemical mechanical polishing; and a polishing method using the same. The composition allows rapid polishing of a polishing surface that contains a silver material for wiring, and makes it possible to obtain a polished surface having a high reflective property. This composition for chemical mechanical polishing comprises (A) abrasive grains, (B) a liquid medium, (C) an oxidizing agent, and (D) a nitrogen-containing hetrocyclic compound. The absolute value of the zeta potential of the (A) component of the composition for chemical mechanical polishing is 10 mV or more. When the content of the (C) component is noted as Mc (mass %) and the content of the (D) component is noted as Md (mass %), Mc / Md is 10 to 200.

The invention discloses a nitrogen-containing heterocyclic compound and an organic electroluminescent device thereof, and relates to the technical field of organic electroluminescent devices. The nitrogen-containing heterocyclic compound provided by the invention has an appropriate energy level structure, excellent charge transfer performance and good thermal stability and chemical stability. When the material is used as a main material of a light-emitting layer of an OLED device, a carrier injection barrier between the light-emitting layer and an adjacent functional layer can be effectively reduced, meanwhile, the driving voltage of the device can be effectively optimized, the light-emitting efficiency is improved, and the service life is prolonged.

The invention relates to an oil-containing sludge biochar catalyst, a preparation method thereof and a method for removing organic pollutants in sewage, the method comprises the following steps: S1, heating a mixture containing saccharides, amino compound raw materials, inorganic alkali and oil-containing sludge for Maillard reaction to obtain a precursor containing a nitrogen-containing heterocyclic compound; wherein the amino compound raw material contains amino acid and / or protein; and S2, in an inert atmosphere, carrying out pyrolysis on the precursor containing the nitrogen heterocyclic compound. The oily sludge biochar catalyst prepared by the method disclosed by the invention has a better catalytic effect on activating persulfate to degrade organic pollutants in a water body.

The present invention relates to nitrogen-containing heterocyclic compounds suitable for use in electronic devices and to electronic devices, in particular organic electroluminescent devices, containing these heterocyclic compounds.

To provide a cured product which suppresses crack formation even when subjected to repeated moisture resistance tests, a laminate including the cured product, and a semiconductor device including the cured product.SOLUTION: The present invention provides a cured product, a laminate containing the cured product, and a semiconductor device containing the cured product. The cured product is obtained by curing a curable resin composition containing at least one resin B selected from the group consisting of a polyimide and a polyimide precursor and a photosensitive agent, in which the Young modulus of the cured product is 2.5 to 6.0 GPa, and the cured product contains a nitrogen-containing heterocyclic compound. A resin A formed after the curing of the resin composition has a repeating unit represented by formula (A-1).SELECTED DRAWING: None

The problem to be solved is to provide a novel herbicide having both high safety for crops and excellent herbicidal activity against weeds in order to resolve the food crisis that is anticipated to come in the near future due to global population growth. The problem is solved by the compound represented by the following general formula (1): or a salt thereof, an agricultural or horticultural herbicide comprising the compound or the salt thereof as an active ingredient, and a method for using the herbicide.

The present invention relates to nitrogen-containing heterocyclic compounds suitable for use in electronic devices, and to electronic devices, in particular organic electroluminescent devices, containing these heterocyclic compounds.

To provide a new compound having inhibitory activity against MYT1, its salts or their solvates.SOLUTION: Wherein, R4 is selected from optionally substituted C6 - C10 aryl and the like; R5 and R6 are taken together with the atoms to which they are attached to form an optionally substituted D ring; D ring is selected from 3 - to 10-membered mono-alicyclic ring and the like; any two adjacent substituents on D ring may be taken together with the atoms to which they are attached to form an optionally substituted E ring. Or a salt thereof, or a solvate thereof.SELECTED DRAWING: None

The invention discloses a nitrogen-containing heterocyclic compound and application thereof. Specifically disclosed is a compound represented by formula I or a pharmaceutically acceptable salt thereof. The compound disclosed by the invention has an inhibition effect on JAK1 kinase; the compound has a good application prospect in preparation of drugs for treating diseases related to JAK1 kinase.

The present invention relates to polymorphs of a nitrogen-containing heterocyclic compound. The polymorphs of the present invention can effectively enhance or reactivate synaptic plasticity, and inhibit or eliminate the accumulation of beta-amyloid, without causing side effects, thereby exerting a therapeutic effect on various nervous system diseases or neurodegenerative diseases. In addition, the polymorphs of the present invention exhibit excellent physicochemical properties, such as stability, solubility, hygroscopicity, and mechanical strength, and show excellent permeability to the blood-brain barrier (BBB).

Provided is a novel photothermal conversion material. A manganese oxide cluster compound represented by general formula (1). (In general formula (1), L is a tricarboxytriptycene residue, alpha1 is an organic acid residue, beta1 is a solvent selected from the group consisting of water and a polar organic solvent having a dielectric constant of 6-47, P1 is a coordinating molecule selected from the group consisting of a nitrogen-containing heterocyclic compound, an oxygen-containing cyclic compound and a phosphine, or a polymer containing the coordinating molecule, [gamma] 1 is a solvent selected from water and a polar organic solvent having a dielectric constant of 6-47, q is a number of 0 < = m < = 8, and m is a number of 0 < = m < = 10. ).

The invention belongs to the technical field of microbiological detection, and relates to a method for detecting the ability of microorganisms to degrade nitrogen-containing heterocyclic compounds and application of the method. The technical problems that in the prior art, a color developing system for directional detection of the degradation capacity of a nitrogen-containing heterocyclic compound is lacked, and traditional absorbance detection has false positive and low accuracy are solved. The detection method provided by the invention comprises the following steps: inoculating bacteria to be detected into a culture medium taking a nitrogen-containing heterocyclic compound as a unique carbon source to prepare a bacterial suspension with initial OD600 of 0.4-0.6; the bacterial suspension and a color developing agent WST-8 or XTT are subjected to a color developing reaction, a reaction solution is obtained, and the initial concentration of the color developing agent in the reaction solution is 250-350 mg / L; the absorbance difference value of the reaction liquid is measured by adopting a dual-wavelength spectrophotometric method and is used for representing the degradation capability of the bacteria to be detected on the nitrogen-containing heterocyclic compound, and the method is high in accuracy. The invention also provides an application of the method in screening nitrogen-containing heterocyclic compound degrading bacteria.

A composition for semiconductor processing according to the disclosure contains (A) a compound represented by the following general formula (1), (B) a compound represented by the following general formula (2), (C) a compound having at least one functional group selected from the group consisting of an amino group and a salt thereof and a hydroxyl group (excluding the compound represented by the following general formula (1), a compound having a carboxyl group and a nitrogen-containing heterocyclic compound) and (D) a liquid medium, and, when the content of the (A) component is indicated by MA [mass %] and the content of the (B) component is indicated by MB [mass %], MA / MB is 1.0×102 to 1.0×104.R2N(OH)  (1)R2NH  (2)(In the formula (1) and the formula (2), R's each independently represent an alkyl group having 1 to 4 carbon atoms).

To provide a dyeing inkjet ink composition having excellent discharge stability and superior wash fastness of a printed product.SOLUTION: A dyeing inkjet ink composition comprises a colorant represented by formula (1), a water-soluble organic solvent, and a nitrogen-containing heterocyclic compound, wherein a total content x (mass%) of the nitrogen-containing heterocyclic compound relative to a total amount of the ink composition satisfies the following relational expression (A): 0<x≤0.5 (A).SELECTED DRAWING: Figure 1

The present application relates to the technical field of synthesis of nitrogen-containing heterocyclic compounds, and particularly relates to a continuous flow synthesis method of nitrogen-containing heterocyclic acetic acid; specifically, nitrogen-containing heterocyclic compounds, halogenated acetic acid ester and inorganic acid binding agent are mixed in an aprotic solvent, and then are introduced into a microchannel of an ultrasonic microchannel continuous flow reactor to perform a substitution reaction under ultrasonic cavitation; after the reaction, the reaction liquid is collected and post-treated to obtain a nitrogen-containing heterocyclic acetic acid ester intermediate; the nitrogen-containing heterocyclic acetic acid ester intermediate is introduced into a second microreactor using an inorganic lye to perform a hydrolysis reaction, and after the reaction, the reaction liquid is collected and post-treated to obtain the nitrogen-containing heterocyclic acetic acid; the present application realizes continuous flow reaction of a heterogeneous system by using emulsification and ultrasonic technology, and can be used for the next step of continuous flow hydrolysis reaction after simple filtration and separation; the present application has high yield of two-step reaction, simple separation, short reaction time, and is suitable for large-scale industrial production.

The invention discloses a non-silicon non-ether type defoamer and a preparation method thereof, wherein a nitrogen-containing heterocyclic compound and a long-chain isocyanate are subjected to a branching reaction under the action of a catalyst to obtain the defoamer; the nitrogen-containing heterocyclic compound structural formula contains 2 to 3 groups, so as to react with the long-chain isocyanate to form a highly branched structure; the long-chain isocyanate structural formula is R-N=C=O, wherein R is a C10-C18 long-chain alkyl, and a relatively long hydrophobic long-chain alkyl can well cope with the foam system for defoaming. The present invention can form a highly branched molecular structure by mixing a nitrogen heterocyclic compound and a long-chain isocyanate, and the defoamer can be defoamed without adding an emulsifier for complex emulsification, and has good temperature resistance, so that the defoamer can be applied to the defoaming and defoaming of a foam system at a higher temperature.

The problem to be solved by the present invention is to provide a novel herbicide that is highly safe for crops and has excellent weed-controlling activity against weeds, in order to address the food crisis expected in the near future due to global population growth. This problem is solved by: a compound represented by the following general formula (I): or a salt thereof; an agricultural or horticultural herbicide containing the compound or its salt as an active ingredient; and a method for using the herbicide.

The invention provides a chemical mechanical polishing solution. The chemical mechanical polishing solution comprises grinding particles, a nitrogen-containing heterocyclic compound, organic acid, a twin anionic surfactant and an oxidizing agent. The chemical mechanical polishing solution has a relatively high copper removal rate, and meanwhile, can remarkably reduce disc-shaped recesses and dielectric layer erosion in a copper wire region on a polished pattern wafer.