124 results about "Thiocarboxylic acid" patented technology

An aqueous process is described in which thiocarboxylate silane is produced from haloalkyl silane by reaction of the haloalkyl silane with an aqueous solution of thiocarboxylate salt in the presence of a catalytically effective amount of alkylguanidinium salt.

The invention provides a plastic composition and a plastic surface metallizing method. The plastic composition contains plastic matrix resin and metal chelate; the metal chelate is a complex of metal ions and organic chelating agent; and the organic chelating agent is at least one of diketone, aminocarboxylic acid, thiocarboxylic acid, polycarboxylic acid and nitrogen-containing heterocyclic compound with a general formula CnH8N2, wherein n is 10, 12 or 14. The plastic surface metallizing method comprises the following steps of: performing injection molding on the plastic composition provided by the invention to form a plastic piece, then performing laser etching on the plastic piece by adopting laser with wavelength of 1,064 nanometers to 1,000 microns, and chemically plating a laser etching area to form a metal plating layer. The organic chelating agent adopted in the plastic composition has low cost and is sensitive to the laser, so the plastic surface has high activation degree; and when the plastic surface is metallized, the infrared laser with lower cost is adopted so that the metal ions of the metal chelate in the plastic piece are decomposed as an active center of subsequent chemical plating and the precision is very high.

The invention provides a preparation method of polymer-coated perovskite quantum dots. The preparation method comprises the following steps: supplying perovskite quantum dots, and dispersing the perovskite quantum dots in a solvent to form a perovskite quantum dot solution, wherein ligands on the surfaces of the perovskite quantum dots comprise thiocarboxylic acid ligands; adding a polymer monomerand a photoinitiator into the perovskite quantum dot solution for reacting under an ultraviolet radiation condition in which the water vapor content is less than 30 percent to generate the polymer-coated perovskite quantum dots, wherein the polymer monomer is an unsaturated polymer monomer containing amidogen.

The present invention provides a quantum dot having a ligand layer on a surface thereof, the ligand layer comprises a malonic acid derivative, a thiothiol compound, a thiocarboxylic acid compound, andmore than one of an ester group and sulfur alcohol group-based compounds. The quantum dot is excellent in oxidation stability, and can be effectively applied to various applications such as a quantumdot film, a color filter, and a quantum dot light-emitting diode.

The invention discloses a high-activity antimony/ titanium composite catalyst, which contains the following components: 1 antimony catalysts, 2 titanium catalysts, 3 first catalyst promoters and 4 second catalyst promoters, wherein the antimony catalysts are oxides and salts of antimony, the titanium catalysts are titanates, the first catalyst promoters are phosphoric acids, phosphorous acids and alkyl groups and/or polyaryl ethers of the phosphorous acids, and the second catalyst promoters are benzothiodiazoles. The antimony/ titanium composite catalyst can be used in a method for preparing polyethylene glycol terephthalate (PET) copolyesters, which includes the following steps: 1 mixing and adding the antimony/ titanium catalyst, the first catalyst promoters, the second catalyst promoters and binary acids into a reaction system, 2 leading the terephthalic acids, esters of the terephthalic acids and excess ethylene glycol to together perform an esterification reaction at temperature of 240-260 DEG C, at pressure of 0.2-0.4MPa and with reaction time of 1-2 hours, and 3 adding copolymerization glycol monomers for a polycondensation reaction to obtain the copolyesters. The antimony/ titanium composite catalyst and the application thereof in the method for preparing the PET copolyesters have the advantages that the catalyst can activate the antimony series catalyst and shortens polycondensation time, and the problem of decreasing of polyester heat stability due to the fact that the antimony series catalyst is apt to yellow products is solved.

The present invention relates to new technological process of converting carboxylic acid into thiocarboxylic acid, and is especially synthesis process of fluticasone acetate. The present invention prepares fluticasone acetate with medicinal level flumethasone as initial material and through one of six technological paths, and has the advantages of short reaction path, high yield, simple reaction condition, high product purity, low cost, etc.

The invention relates to a preparation method for preparing water-soluble nanoparticles by adopting a ligand exchange method. The method comprises the following specific steps of: introducing two water-soluble polyethylene glycol chains onto iminodiacetic acid; reacting the compound with carbon bisulfide to generate a carbon bisulfide derivative which has a thiocarboxylic acid structure and serves as a ligand; and performing ligand exchange on the obtained ligand and oil-soluble nanoparticles to obtain stable water-soluble nanoparticles. The water-soluble nanoparticles prepared by the method can be suitable for a plurality of fields of biology, photoelectric materials, catalysis and the like.

Provided is a technology for preparing a terminated-type sulfur-containing silane coupling agent through a hydrosilation method. First, acyl chloride and sodium sulfide or sodium bisulfide are reacted in a water phase to prepare an aqueous solution of sodium thiocarboxylate; under catalysis of phase-transfer catalysts, the aqueous solution of sodium thiocarboxylate is reacted with chloropropene, and thiocarboxylate allyl ester, liquid separation is carried out, after low-boiling-point substance removal, thiocarboxylate allyl ester and trialkoxysilane are subjected to a hydrosilation reaction under action of platinum catalysts, and after the reaction is over, a finished product silane coupling agent is obtained after low-boiling-point substance removal and decolouring steps. The raw material utilization rate is raised, The hydrosilation reaction process keeps anhydrous state, hydrolysis of alkoxy silane is inhibited, and the storage stability of the silane coupling agent is raised.

The present invention relates to a method for determining the concentration of iron ions in a hydrocarbon composition, as well as reagents and kits for use in such methods. The method utilises a thiocarboxylic acid having formula (I) which reduces the ferric ions and complexes ferrous ions producing a colored solution, which can be analysed to determine the amount of iron ions in the starting sample.

The invention relates to the field of environmental protection, and specifically relates to preparation of a carbodithioic acid-modified heavy metal adsorbing material, and application of the material for removing Cu<2+> in wastewater. The technological process comprises the following steps: (1) pretreatment of chlorine balls; (2) preparation of amino microspheres; (3) modification of amino resin by carbodithioic acid; (4) Cu<2+> adsorption property. The carbodithioic acid-modified chelating resin provided by the invention integrates physical adsorption and chemical adsorption, the preparation steps are simple, and the grafting percent of the amino resin is up to 70%. The resin uses insoluble and infusible crosslinked polystyrene as a matrix, and is good in acid and alkali resistance. The adsorption effect of the resin is higher than that of other types of resin, the 3.17*10<-4> moL.L<-1> Cu<2+> adsorption rate is 96%, the wastewater discharge can reach the primary standard (less than 0.5ppm) in China, and the resin is suitable for recycling a large number of Cu<2+> in wastewater in industrial cities and Cu<2+> salt production enterprises, and has good application prospects.

The invention relates to a preparation method of fluticasone furoate, especially preparation and purification of an intermediate 6alpha, 9alpha-difluoro-17alpha-[(2-furylcarbonyl)oxy]-11beta-hydroxy-16alpha-methyl-3-oxo-androstane-1,4-diene-17beta-thiocarboxylic acid. The preparation method comprises the following steps: in the presence of alkali and alcoholic solvent, a compound as shown in the formula VIII is converted into a mixture containing the compound of formula II; the mixture containing the compound of formula II is mixed with an aqueous solution of inorganic base and an ester solvent; a water phase is separated; pH value of the water phase is regulated by the use of acid until a solid is precipitated out; and the solid is separated. The invention provides a preparation method capable of remarkably raising purity of fluticasone furoate. Safety of drug application is guaranteed.

The invention discloses a preparation method of fluticasone propionate, 6 Alpha, 9 Alpha- difluoro-ll Beta-hydroxide radical-16 Alpha-methyl-17 Alpha- propionyloxy-3-androsterone-1, 4-diene-17 Beta- thiocarboxylic acid is put into solvent to be reacted with monobromomethane when alkali exists, then the products from the reaction are reacted with tetraalkyl fluorizate ammonium salt or M+F- when ion liquid and solvent exist, finally the target products are collected from the reaction products. The method of the invention has simple operation, high yield, low cost and easy disposal after reaction, thereby having good industrial production prospect.

The invention discloses a preparation method for synthesis of phenolic ester through a thiocarboxylic acid mediated visible light catalyzed phenol acylation reaction. Thiocarboxylic acid compounds andphenol compounds are subjected to a site specific reaction under certain conditions to produce phenolic ester compounds, wherein the certain conditions are as follows: under the conditions of normaltemperature, normal pressure and visible light, K2CO3 is used as an alkaline catalyst, terpyridyl ruthenium dichloride hexahydrate is used as a photosensitizer and acetonitrile is used as a reaction solvent. Synthesis of phenolic ester under catalysis of visible light is realized, thiocarboxylic acid is used as an acylation reagent, and the site specific phenol esterification reaction is realizedefficiently under mild conditions of normal temperature, normal pressure and visible light. The method has mild reaction conditions, large substrate functional group tolerance, high applicability andhigh yield, and an efficient, reliable and economical preparation method is provided for synthesis of phenolic ester.

The invention provides a salt-free preparation method for substituted taurine, and belongs to the technical field of organic synthesis. Nitroolefin and thionocarboxylic acid serving as raw materials are subjected to addition, oxidation and reduction to form the substituted taurine; and particularly, the method can be used for preparing cis and trans disubstituted and trisubstituted taurine. The preparation method has the advantages of simple and readily available raw materials, convenient operation and no troublesome desalting purification process, and suitability for large-scale industrial production. The compounds prepared by the method can be used as nutrient substances, medicaments, enzyme inhibitors, antibacterial agents, surfactants, plant growth regulators, raw materials for preparing sulfonamido peptide and the like.

The invention discloses an electrochemical oxidation synthesis method for amide and application thereof, and belongs to the technical field of electrochemical organic synthesis. According to the synthesis method for the amide, thiocarboxylic acid or thiocarboxylate and amine are adopted as reaction raw materials, firstly, the thiocarboxylic acid or the thiocarboxylate is oxidized through an anodein an electrolytic tank so as to form free radical intermediates, then the two free radical intermediates are coupled so as to form a key intermediate disulfide compound, and then nucleophilic addition-elimination reaction is carried out on the disulfide compound and the reactant amine so as to generate an amide compound. The synthesis method has the advantages that no catalyst needs to be added,in addition, the reaction conditions are mild, by-products are few, synthesis and purification of the amide compound are facilitated, and the method has wide application in preparation of amide drugsin drug synthesis.

This invention relates to a new method for the stereospecific thiocarboxylation of organic compounds for the preparation of compounds according to formula (I):

wherein a compound of formula (II):

is reacted with a compound of formula (IIIa) or (IIIb):

then treating the obtained product with a thiocarboxylic acid or a salt thereof, and subsequently carrying out a nitration reaction.

The invention discloses a sulfhydryl compound containing beta-ester groups and an acetyl-transferred synthesis method thereof. The method comprises the following steps of: under the protection of nitrogen gas, adding a compound or epoxy resin containing 1mol of epoxy groups, 5-100mol of solvent, 0.5-2mol of organic amine and 1.01-1.5mol of monothiocarboxylic acid into a reactor in sequence and reacting for 1-24h at -10 DEG C to 30 DEG C; washing by dilute hydrochloric acid; evaporating to remove the solvent; and, removing the excessive monothiocarboxylic acid by the vacuum evaporation or the column chromatography to obtain the sulfhydryl compound containing the beta-ester groups. The method provided by the invention has the advantages of rapidness, high efficiency and simple and convenient process. A lot of epoxy resins can be converted into the sulfydryl resin. The application prospects of the sulfhydryl compound in the functional macromolecular materials, the thermosetting high-performance materials and the additives and the like are wide.