The invention discloses a municipal solid waste pyrolysis and gasification process. The municipal solid waste pyrolysis and gasification process comprises the following steps of a, crushing, wherein the size of crushed waste ranges from 2 cm to 2.5 cm; b, drying dehydration, wherein the crushed municipal solid waste is conveyed into a biology drying bin to be subjected to microorganism dehydration, and a microbial agent is used for treatment; c, sorting, wherein the dried waste is sorted into three classes, inorganic matter, gasifiable matter and waste metal; d, respective treatment; and e, waste gas treatment. According to the process, the municipal solid waste is crushed into the specified particle size and then put into the biology drying bin to be treated through the aerobiotic high-temperature-resisting microbial agent, the municipal solid waste is subjected to drying dehydration, the water content is reduced, waste drying is ensured, and sorting treatment of the next step is facilitated; the gasifiable matter is combusted to be used for power generation and heat supply, and energy consumption and treatment cost are further reduced; and by means of the process, large-scale treatment can be achieved, no dioxin gas is generated, the occupied area is not large, the additional value of the municipal solid waste can be increased, and the process is worth of application and popularization.