The invention discloses a laser diode pumping Kerr-lens mode locking Yb:(YLa)2O3 all-solid-state femtosecond laser device. Yb:(YLa)2O3 laser ceramics, a pumping source, an optical coupling focusing system, two concave mirrors, two triple prisms, a GTI reflecting mirror, a plane mirror and an output mirror are arranged. According to the device, Kerr-lens mode locking is achieved on the Yb:(YLa)2O3 laser ceramics at the first time, 170 fs of mode locking pulses are output, the half-width of a mode-locking pulse spectrum is 7.7 nm, and the average output power is 140 mW. The device has the advantages of being good in practicability and operability, compact, small and exquisite in structure, suitable for repeated production and assembling, and mass production and lower in cost, achieving single-way laser output, high repetition frequency and femtosecond magnitude pulse width, and being high in stability and light beam quality, can be widely applied to the fields of national defense, industries, medical treatment and scientific research, and has the good application prospects and commercial value.