The present invention relates to a method for simultaneously extracting
limonin and crude fat from pomelo
nucleus by using a
solvent acetone. The method comprises: (1) pretreatment: peeling pomelo
nucleus to obtain pomelo
nucleus kernel,
drying the pomelo nucleus kernel, and breaking; (2) extraction: adding an
acetone solvent to the broken pomelo nucleus kernel, extracting 1-7 times, and recovering the
solvent to obtain a mixture; and (3) separation: adding an
ethanol aqueous solution with a
volume fraction of 50-95% to the mixture, stirring, carrying out static layering or
centrifugation to obtain crude fat and an
ethanol solution containing
limonin, and recovering the solvent in the solution to obtain
limonin. According to the present invention, limonin and crude fat are simultaneously extracted from the pomelo nucleus by using the one solvent
acetone, wherein the
recovery rates of limonin and crude fat can respectively achieve more than 95% under the preferred conditions, the product is easy to separate, and acetone is the renewable solvent, has the low
boiling point, and is easily recycled; the method is easy to enlarge, can be used for large-scale production, does not requirecomplicated equipment, and is easy to operate; and the prepared limonin can be used as the
drug preparation
raw material, and the crude fat can be used as food and feed after being refined, and can beused as the
raw material for the preparation of fine chemicals, slow release fertilizers or
controlled release fertilizers.