17 results about "Limonin" patented technology

The invention relates to application of limonin as a pesticide synergistic aid in prevention and control of corn pests, which utilizes the characteristic that low-concentration limonin has a remarkable synergistic effect on chemical pesticides, 0.5-4g / mL limonin, 5% chlorantraniliprole and 25% thiamethoxam are mixed for use, so that the lethal medium concentration (LC50) of the limonin to corn borers, corn aphids and rhopalosiphum padi can be remarkably reduced; the insecticidal effect of chlorantraniliprole on corn borer and the insecticidal effect of thiamethoxam on aphid are improved. A field pesticide effect test also shows that the field prevention and control effect of the pesticide on Lepidoptera pests such as ostrinia nubilalis is remarkably improved by mixing 4 g / mL of limonin and 5% of chlorantraniliprole, the actual field dosage of chemical pesticides is reduced, the purposes of pesticide reduction and synergism are achieved, and a positive effect is achieved on comprehensive prevention and control of the field pests.

The invention discloses application of limonin in preventing and treating bacterial wilt of cigars. According to the method, limonin is applied by adopting a foliar spraying method, so that the relative control effect of cigars on bacterial wilt can be remarkably improved, and the morbidity of the bacterial wilt of cigars is reduced.

The invention relates to the technical field of tea processing, in particular to a method for preparing special tea through compound fermentation of pansy petals and bergamot fresh leaves and application of the special tea. According to the method, the pansy petals and the bergamot fresh leaves are mixed according to a specific proportion, synergistic fermentation is performed in a high-pressure CO2 environment, and aromatic substances, anthocyanin and flavonoid compounds in the pansy petals are fully combined with citrus aromatic substances and active ingredients in the bergamot leaves by accurately controlling parameters such as temperature, humidity and CO2 concentration. The prepared tea product has the flower fragrance of the pansy and the citrus fragrance of the bergamot, is orange red and bright in soup color, is rich in nutritional ingredients such as anthocyanin, flavonoid, limonin and vitamin C, and has the effects of tranquilizing and allaying excitement, resisting oxidation, promoting digestion and relieving anxiety. The invention also relates to application of the tea product in the fields of food, health care products and cosmetics.

The invention relates to a fruit extract preparation process based on enzymolysis and ultrasonic synergistic treatment, which comprises the following steps: S1, crushing citrus pomace, drying, sieving, adding cellulase, pectinase, beta-glucosidase and deionized water, uniformly stirring, adjusting the pH value, and carrying out enzymolysis at a constant temperature to obtain a mixture; s2, cooling the mixture, carrying out ultrasonic treatment, then heating for enzyme deactivation, centrifuging, and collecting supernate to obtain a crude extract; and S3, adsorbing the crude extract through adsorption resin, eluting, concentrating, crystallizing and drying to obtain the extract. The preparation process provided by the invention has relatively high limonin extraction rate and purity.

The invention provides application of five bitter substances in evaluation of bitter degree of hericium erinaceus and an evaluation method, and belongs to the technical field of quality monitoring. The invention provides application of five bitter substances, namely Limonin, Picrasin b, Fissinolide, Pristimulin and Samaderin a, in evaluating the bitter degree of the hericium erinaceus, the five bitter substances in the hericium erinaceus to be evaluated are extracted and separated, the content of the five bitter substances is detected, and the bitter degree of the hericium erinaceus is evaluated according to the correlation between the content of the five bitter substances and the bitter value of the hericium erinaceus. According to the method, the content of the five bitter substances and sensory evaluation are subjected to conjoint analysis, the correlation between the content of the five bitter substances and the bitter degree of the hericium erinaceus is confirmed, and a simple, convenient and scientific basis is provided for evaluating the bitter degree of the hericium erinaceus.

This invention discloses a method for extracting limonin, comprising the following steps: S1, preparing an extract containing limonin; S2, adding macroporous resin to the extract and stirring, the macroporous resin being used to adsorb limonin in the extract; S3, removing the macroporous resin from the extract and placing it in a chromatography column to collect the eluent; S4, evaporating and concentrating the eluent to obtain a limonin extract, using ethyl acetate as a washing solvent, ultrasonically dissolving the limonin extract, then adding pure water for washing, concentrating and evaporating the washing solution to obtain a limonin sample; S5, performing TLC directional analysis on the limonin sample to check whether the limonin sample is qualified. This invention improves the extraction rate of limonin and yields a high extraction content.

The invention relates to the field of natural products, and relates to application of limonin compounds or medicinal derivatives thereof in preparation of medicines for preventing or treating inflammation. The inventor of the invention finds for the first time that the compound I or the compound II extracted and separated from the mallotus oblongifolius can significantly inhibit the content of inflammatory factors of immune cells at an extremely low concentration, and can be used for preparing medicines for preventing or treating inflammation. Besides, the compound I or II can significantly reduce the expression level of LPS-induced inflammatory factors TNF-alpha, IL-1alpha, IL-1beta, IL-6 and IL-18 at a low concentration, and does not affect the survival of immune cells, which proves that the compound I or II can inhibit the expression of inflammatory factors and has a strong anti-inflammatory effect.

The application provides an anti-termite sealing material of silica gel foam and a preparation method thereof, and belongs to the technical field of polymer sealing materials. The raw material formula of the anti-termite sealing material of silica gel foam is as follows: vinyl silicone oil, reinforcing filler, flame-retardant filler, contact killing agent, bait agent, odor agent, structure control agent, inhibitor, platinum catalyst, foaming agent, hydroxyl silicone oil and hydrogen-containing silicone oil; wherein the contact killing agent is one or more of pyrethroid, neonicotinoid, phenylpyrazole, boric acid, glycine, erythritol and fipronil; the bait agent is one or more of diatomite, talcum powder, capsaicin, dihydrocapsaicin and denatonium benzoate; and the odor agent is one or more of camphor oil, peppermint oil, limonin, limonene, citral, decanal, octanal and nonanal. The anti-termite sealing material of silica gel foam has excellent flame-retardant performance, mechanical performance and anti-termite biting performance, and can well protect the integrity of the sealing material.

This invention discloses the application of limonene in the preparation of drugs for alleviating or improving vascular calcification. Intervention with limonene in CKD mouse models and primary vascular smooth muscle cells (VSMCs) significantly inhibited aortic calcification in CKD mice, significantly reduced high-phosphorus-induced osteogenic differentiation and calcium deposition in VSMCs, inhibited reactive oxygen species (ROS) production, reduced cellular iron accumulation, and alleviated ferroptosis. The findings of this application are highly likely to provide effective clinical drugs for the prevention and treatment of vascular calcification in CKD.

The invention discloses a special organic fertilizer for preventing and controlling tobacco black shank and a preparation method thereof.The special organic fertilizer is prepared from corn straw, rice husk charcoal, a biological leavening agent, limonin, salicylic acid, plant ash, shrimp shell powder and soluble potassium silicate, and the biological leavening agent is tarlaromyces flavus powder; the preparation process comprises the following steps: acidizing the prawn shell powder, crushing and fermenting the corn straws, the rice husk charcoal and the acidized prawn shell powder, increasing the activity of the tarlaromyces flavus powder by using limonin and salicylic acid, carrying out secondary fermentation, and finally granulating and drying. The growth and development of tobacco root systems are promoted, the stress resistance of the tobacco is enhanced, and the occurrence of soil-borne diseases is reduced, so that the yield of the tobacco is increased. Meanwhile, the tobacco absorbs more comprehensive and balanced nutrients, and the internal quality of the tobacco leaves is improved.

The present application relates to the technical field of health food, and provides a kind of nutrition food for regulating intestinal homeostasis and improving irritable bowel syndrome and its preparation process.The present application includes the following contents:(1) preparing astaxanthin nanoparticle powder by alkaline electrolytic water-ultrasonic coupling technology;(2) mixing the astaxanthin nanoparticle powder with limonin, vitamin D3, oryzanol, water or solid filler accessory in proportion to obtain a mixture;(3) homogenizing and filtering the mixture, or sieving the mixture;(4) sterilizing and filling the mixture, or tabletting and granulating the mixture to prepare a product.The present application can effectively regulate intestinal homeostasis and improve irritable bowel syndrome, and the product can be prepared into capsules, tablets, granules, oral liquids or beverages.The production process is simple, the cost is low, and the present application is suitable for large-scale industrial production.

The application relates to application of limonin as a pesticide synergist in corn pest control, and the characteristics that low-concentration limonin has a significant synergistic effect on chemical pesticides. 0.5-4 mu g / mL limonin is mixed with 5% chlorantraniliprole and 25% thiamethoxam for use, the lethal concentration (LC50) of the mixture to corn borer, corn aphid and Sitobion avenae can be significantly reduced, and the insecticidal effect of chlorantraniliprole on corn borer and thiamethoxam on aphids is improved. Field efficacy tests show that 4 mu g / mL limonin mixed with 5% chlorantraniliprole not only significantly improves the field control effect of the pesticide on lepidopterous pests such as corn borer, but also reduces the actual field use amount of the chemical pesticide, that is, the purpose of reducing the pesticide and improving the synergistic effect is achieved, and the method has a positive effect on comprehensive field pest control.

This invention provides a non-bitter, highly clarified, and flavonoid-rich pomelo rice wine and its preparation method, belonging to the field of functional rice wine technology. This invention uses pomelo juice, rice wine body, vitamin C, and citric acid as raw materials. It employs a targeted enzymatic debittering process to specifically degrade bitter precursors such as naringin and limonene, completely eliminating bitterness and astringency. A low-temperature, oxygen-free extraction technique is used to accelerate the gentle dissolution of pomelo flavor and functional components, avoiding the release of bitter substances and the degradation of heat-sensitive components. A β-cyclodextrin encapsulation technique is used to selectively encapsulate bitter substances such as naringin and limonene, achieving debittering without loss of functional components and flavor. A freeze-sedimentation process is used to fully extract unstable substances and easily crystallized components that are difficult to settle at room temperature, further improving shelf-life stability. The pomelo rice wine prepared by this invention has the advantages of a non-bitter taste, high stability, and high flavonoid content, making it easy to achieve large-scale mass production.

This invention relates to the field of natural medicines, and particularly to a limonin compound, its preparation method, and its application. This invention provides a limonin compound having the structure shown in any of compounds 1-8. Data from the examples show that the limonin compound provided by this invention can inhibit the assembly of the NLRP3 inflammasome by inhibiting ASC oligomerization, thereby reducing the generation and release of downstream inflammatory factors and exerting an anti-inflammatory effect.

The present application belongs to the field of food processing and biomedicine, and discloses a gel preparation with anti-hepatic inflammatory aging effect and application thereof. The gel preparation is a gel preparation formed by coating limonin with pectin; the neutral sugar content of the pectin is 15wt%-40wt%, and the methoxyl content is 5wt%-15wt%; and the embedding mass ratio of limonin to pectin is 1:5.5-1:9.5. The gel of the present application realizes the regulation of the embedding amount of limonin through the difference in the neutral sugar content and the methoxyl content of pectin. The gel preparation of the present application significantly improves the inhibitory effect on the inflammatory factor IL-18 and the aging-related protein p21 of hepatic inflammatory aging, and significantly improves the promoting effect on the hepatic regeneration-related protein RB, and reduces the dosage of limonin. The gel preparation of the present application has a synergistic anti-hepatic inflammatory aging effect, and is used for anti-hepatic inflammatory aging drugs, food or dietary supplements.

The invention belongs to the technical field of food processing, and particularly relates to teak high-activity oral liquid with stability, oxidation resistance and lipid lowering performance and a preparation method and application of the teak high-activity oral liquid. According to the oral liquid, teak dietary fibers are used as a core active component and matched with limonin, sucrose fatty acid ester and mono-and diglycerides fatty acid ester are compounded and emulsified, and an ultrasonic dispersion-high-speed shear emulsification-composite homogenization process is combined, so that the technical problems that the dietary fibers are easy to gather and the limonin is difficult to dissolve in water are solved. The preparation method comprises the following steps: preparing a water phase containing dietary fibers and related auxiliary materials and an oil phase containing limonin, emulsifying, performing ultrasonic treatment, homogenizing and sterilizing to obtain a finished product. The teak oral liquid has the beneficial effects that the oral liquid has antioxidant and lipid-lowering functions, realizes high-value utilization of teak low-value resources, and is suitable for functional food development.

The invention provides a citrus reticulata pulp juicing production line and a production method. In the preparation process of Xinhui pericarpium citri reticulatae, the remaining part (namely, citrus pulp balls) obtained after tea branch citrus fruits are peeled is soaked in a soaking solution in a soaking pool through an astringency and bitterness removing processor, limonin and naringin contained on the surfaces of the pulp balls are dissolved, astringency and bitterness of the citrus pulp balls are removed, and then the citrus pulp balls are subjected to vacuum drying to obtain the tea branch citrus peel. Soaking liquid on the citrus pulp balls is flushed by cleaning water in the cleaning pool through the bubbling cleaning machine, finally, the flushed citrus pulp balls are extruded in a screw type extrusion mode through the pulp juicer, and finally the citrus juice is prepared, so that waste of the citrus pulp balls is avoided, and meanwhile, the commodity vacancy of the citrus juice in the market can be made up; the invention belongs to the technical field of automatic equipment.