779results about How to "Good pain relief" patented technology

A method of repairing a defect in an annulus fibrosus of an intervertebral disc, without excising the entire nucleus pulposus of the disc. The method includes inserting an introducer needle through the annulus fibrosus by puncturing the annulus fibrosus with the introducer needle, injecting an in situ curable, bio-compatible polymerizable or polymeric material composition into the disc through the introducer needle directly or indirectly so that the in situ curable composition contacts a defect in the annulus fibrosus; and curing said material in situ.

A method of treating a subject having a musculoskeletal disorder includes administering to a subject's articular site in need thereof an effective amount of a hyaluronic acid (HA) composition. In one embodiment, the HA composition includes an HA derivative, wherein carboxyl functionalities of the hyaluronic acid derivative are each independently derivatized to include an N-acylurea or 0-acyl isourea, or both N-acylurea and 0-acyl isourea. In another embodiment, the HA composition includes a crosslinked HA gel that is prepared by reacting an uncrosslinked HA with a biscarbodiimide in the presence of pH buffer in a range of between about 4 and about 8. The composite can optionally include at least one second bioactive agent other than the HA derivative, such as a steroid.

Methods and materials, including novel compositions, dosage forms and methods of administration, useful for treating arthritic conditions, inflammation associated with a chronic condition, and/or chronic pain, including pain from arthritis and inflammation, using opioid antagonists, including combinations of opioid antagonists and opioid agonists. Methods and materials comprising opioid antagonists or combinations opioid antagonists and agonists may optionally include one or more additional therapeutic agents.

Apparatus for delivering biologic sealant device that includes a pressure monitor coupled to the delivery device to measure pressure within the device. A method of treating a disc using the device as well as a kit including the device is described.

The invention relates to monitoring of pain-related responses in a patient in order to detect the level of pain experienced by the patient. At least one first measurement signal is acquired from the patient and at least one of the signals is transformed into a normalized signal having a predetermined value range. Based on the at least one normalized signal obtained in this way, a threshold condition is set and a rate at which at least one second measurement signal fulfills the threshold condition is monitored, wherein each of the at least one second measurement signal is derivable from a corresponding normalized signal and indicative of pain-related activity in the patient. The level of pain experienced by the patient depends on the rate monitored.

A method for the treatment of pain and/or inflammation in a subject by the administration of N-acetyl-cysteine (NAC) or derivative thereof and a pain and/or anti-inflammatory medication. The pain or anti-inflammatory medication is metabolized by the action of the cytochrome p450 system. The pain medication includes N-methyl-D-aspartate (NMDA) receptor antagonist(s). NAC and the pain medicine can be administered concurrently or sequentially. The joint administration can result in the use of lower dosages than typical dosage of the pain and/or anti-inflammatory medication or in enhanced relief from the treated condition.

The invention relates to a nakedflower beautyberry extract as well as a preparation method, a preparation and an application thereof. The nakedflower beautyberry extract is an extract which is extracted from nakedflower beautyberry leaves and contains a nakedflower beautyberry total flavonoid compound and a tannide class compound. The extract is obtained by the steps of extracting the nakedflower beautyberry leaves by water, diluted alcohol or diluted ketone and carrying out macroporous adsorptive resin column chromatography purification on an extracting solution after being concentrated. The nakedflower beautyberry extract has high purity and has the functions of bacteriostasis, hemostasis, pain relieving and convergence.

The invention discloses an aloe gel skin-care product and a preparation method thereof, and the aloe gel skin-care product comprises the following components by weight: 30.0%-98.0% of aloe gel fresh juice, 0.00%-5.00% of purslane extracts, 0.00%-5.00% of beta-glucan, 0.00%-0.20% of sodium hyaluronate, 0.00%-0.50% of allantoin, 0.00%-4.00% of vitamin B5, 1.00%-10.0% of polyols, 0.30%-2.00% of carbomer, 0.00%-10.0% of glyceride polyacrylate, 0.01%-0.30% of preservatives, 0.05%-0.20% of EDTA-2Na, 0.20%-1.50% of triethanolamine, and 0.00%-50.0% of deionized water. The aloe gel skin-care product of the invention has good stability and compatibility, has excellent efficacy of moisture retention, moisturization, inflammation removal, analgesia, irritation resistance, and rapid healing promotion for skin damaged tissues.

The invention discloses a cancer pain-relieving plaster prepared by a preparation A and a preparation B, wherein the preparation A is prepared by five branches, five skins, one brick, one stone, five cores, and the like; the preparation B is prepared by poria cocos, pinellia ternate, jackinthepulpit tuber rhizome, trichosanthes kirilowii maxim, centipede, zaocys dhumnade, and the like. When the cancer pain-relieving plaster is prepared, the preparation B is added into the preparation A to be decocted for 4.5-5.5 hours, red lead is added to be mixed to pasty fluid, then cold water is added for steeping to releasing fire-toxin, water is changed once one day, and the plaster is obtained after steeping for 7 days. When the plaster is used, the plaster is coated on cotton cloth or plaster paster. The cancer pain-relieving plaster mainly aims at tumour cancers of lung cancer, gastric cancer, liver cancer, pancreatic cancer, colon caner, rectal caner, kidney cancer, bladder caner, breast cancer, cervical cancer, ovarian cancer, esophagus cancer, laryngeal cancer, and the like and is obvious in pain-relieving effect.

Apparatus and methods for managing pain uses separate varying electromagnetic fields, with a variety of temporal and amplitude characteristics, which are applied to a particular neural structure to modulate glial and neuronal interactions as a mechanism for relieving chronic pain. In another embodiment, a single composite modulation/stimulation signal which has rhythmically varying characteristics is used to achieve the same results as separate varying electromagnetic fields. Also, disclosed is an apparatus and method for modulating the expression of genes involved in diverse pathways including inflammatory/immune system mediators, ion channels and neurotransmitters, in both the Spinal Cord (SC) and Dorsal Root Ganglion (DRG) where such expression modulation is caused by spinal cord stimulation or peripheral nerve stimulation using the disclosed apparatus and techniques. In one embodiment of multimodal modulation therapy, the prime signal may be monophasic, or biphasic, in which the polarity of the first phase of the biphasic prime signal may be either cathodic or anodic while the tonic signal may be either monophasic, or biphasic, with the polarity of the first phase of the biphasic tonic signal being either cathodic or anodic.

Provided are pharmaceutical compositions and methods for the alleviation of pain in a patient with optimal ratios of morphine and oxycodone that provide superior analgesic efficacy and lower incidence of adverse side effects compared to morphine and oxycodone alone. The pharmaceutical compositions comprise morphine and oxycodone, or pharmaceutically acceptable salts thereof, in ratios of about 3 to 2 to about 1 to 2, morphine to oxycodone by weight.

The invention relates to the technical field of crude drug, more specifically to a linaloe leaf extract. The invention also discloses its preparation and use in pharmaceuticals and health products.

The invention discloses a graphene heat-emitting film assembly with a single-side far infrared radiation function and a bed warmer based on the graphene heat-emitting film assembly. According to the graphene heat-emitting film assembly of the invention, one surface of a graphene heat-emitting film layer, which is far away an electrode layer, is provided with a far infrared reflecting layer. The graphene heat-emitting film assembly disclosed by the invention has an excellent infrared reflection effect and is more energy-saving; the bed warmer based on the graphene heat-emitting film assembly has the advantages of good heat-emitting stability, high temperature rise speed, uniform heat emission and soft material, and can realize the physical therapy functions of promoting blood circulation, repairing cells, preventing diseases and the like..

The invention provides a medicinal composition for treating exogenous fever and process for preparation, wherein the composition is prepared mainly from capsule of weeping forsythia, prepared soybean, mentha, Schizonepeta tenuifolia, Bupleurum root, cape jasmine, rhubarb horsetails, sweet wormwood, radix paeoniae rubrathe, areca-nut, magnolia bark, baikal skullcap root, pinellia tuber and licorice root.

Apparatus and methods for managing pain uses a single composite modulation/stimulation signal with variable characteristics to achieve the same results as separate varying electromagnetic signals. The composite signal is utilized for modulating the expression of genes involved in diverse pathways including inflammatory/immune system mediators, ion channels and neurotransmitters, in both the Spinal Cord (SC) and Dorsal Root Ganglion (DRG) where such expression modulation is caused by spinal cord stimulation or peripheral nerve stimulation using the disclosed apparatus and techniques.

The Chinese patent medicine for curing gynecopathy is made up by using 30-odd Chinese medicinal materials of ginseng, notoginseng, ass hide glue, velvet deerhorn, Chinese angelica root, cooked rehmannia root and others. Said invention also provides its preparation method, and said Chinese patent medicine can be made into capsule preparation.

The invention discloses a Chinese medicine combination for treating cardio-cerebral vascular diseases, which is composed of raw materials with the following parts by weight: 30-50 parts of radix astragali, 20-25 parts of angelica, 15-20 parts of hemlock parsley, 30-50 parts of salvia miltiorrhiza, 15-20 parts of pseudo-ginseng, 15-20 parts of hawkthorn and 20-30 parts of radix puerariae; the Chinese medicine combination of the invention has ingenious compatibility, simple prescription, broad source of raw materials, low price as well as the efficacies of tonifying both qi and blood, balancing yin and yang, activating blood circulation and dissolving stasis; the Chinese medicine combination can soften blood vessels through reducing blood fat and blood viscosity and eliminating blood scales and finally achieve the purposes of smoothing blood circulation and activating cardio-cerebral function; furthermore, the Chinese medicine combination has unique efficacy for resisting atherosclerosis as well as significant curative effect on cardio-cerebral vascular diseases like coronary heart disease, cerebral thrombosis, and the like; the total clinical effective rate can reach over 95% and the Chinese medicine combination can achieve good preventive and health care effect through long-term oral administration and has safe oral administration and no toxicity and side effect.

The invention discloses a method of using dopamine for rapidly crosslinking chitosan to prepare hemostatic sponge, and belongs to the field of biomedical materials. The dopamine is adopted to react with amidogen on a chitosan chain, and meanwhile a self-polymeric reaction is performed, so that chitosan chain sections are crosslinked to form a cross-linked network structure, and the obtained chitosan sponge has the certain mechanical strength. In the reaction process, the oxidizing agent sodium periodate is added to accelerate the reaction, and therefore the time spent for preparing the chitosan hemostatic sponge can be greatly shortened. The chitosan hemostatic sponge has the good biocompatibility, also has the strong water expansion performance, mechanical performance, water retention and moistening performance and biodegradability, has the good analgesic and hemostatic effects, prevents wound contamination and infection, promotes healing of injured tissue, and can be possibly applied to clinical first aid and hemostasis.

A functional dressing (film) comprises an edge remaining film 1 and a fixed pasting film 2 which are convenient to separate from each other, wherein a functional pad 3 is arranged between the edge remaining film 1 and the fixed pasting film 2, a protective film 4 is arranged on the face, with the back towards the functional pad, of the fixed pasting film, and a plurality of layers of annular adhesive tape or adhesive tape shaped like a Chinese character 'hui' is arranged on the fixed pasting film. Thus, on the one hand, the binding area of the fixed pasting film and the skin is reduced, and on the other hand, sweat can volatilize through reserved gap; due to the fact that a functional layer and a moisture-preserving layer are arranged in the functional pad, medicine ingredients in the functional layer and the moisture-preserving layer act on wounds and peripheral tissue, and the functional dressing (film) has the functions of stopping bleeding, resisting and preventing bacteria, diminishing inflammation, easing pain, promoting healing, reducing scar formation and accelerating local blood circulation.

The invention discloses a plaster for treating pains in neck, shoulder, waist and legs. The plaster is made by mainly using Caulis Sinomenii, Aconitum kusnezoffii, Radix Aconiti, Boswellia carteri, myrrh, Viciaamoena Fisch, centipede, Ligusticum wallichii, Common Threewingnut Root, rhizoma corydalis, dahurian angelica root, ramulus mori, Semen Brassicae, scorpio, pawpaw, Zoacys Dhumnades, Radix Clematidis, dragon's blood, Mythic Fungus, Salvia miltiorrhiza, Rhizoma Cibotii, Panax Notoginseng, Incised Notopterygium, Radix Angelicae Pubescentis, medicine called Lingxian Divaricate Saposhnikovia Root, Radix Stephaniae Tetrandrae, Gentiana macrophylla, Rhizoma Drynariae, unprepared Polygonum multiflorum Thunb, tortoise shell, Nux Vomica, stir-baked squama manitis, lumbricus, rhizoma corydalis, borneol, Manchurian wildginger, Herbal Ephedrae, Cortex Acanthopanacis, safflower, camphor and rosin. The plaster is a special medicine for treating rheumatoid arthritis, traumatic injury, pains in neck, shoulder, waist and legs, and hyperosteogeny patients, is a traditional black plaster dosage form prepared with Chinese herbal medicines as raw materials, is a traditional Chinese medicinal plaster dosage form with definite therapeutic effects, and cures more than 100000 patients through the combination of traditional Chinese medicinal channel and collateral theory and local infected position application treatment.

The invention discloses a preparation method of a medical bandage coated with a polyurethane resin prepolymer. The preparation method comprises the following steps: a. adding aromatic diisocyanate and a dehydrating agent to a reaction kettle, stirring, adding polyether glycol, polyether triols, high molecular polyethylene glycol, a defoaming agent, white carbon black, a lubricant and a catalyst, heating up to 75 DEG C and preserving heat, and then cooling to room temperature to obtain a polyurethane prepolymer; b. adding powdery nanoparticles, zinc oxide and a far infrared emitting material to absolute ethyl alcohol and a coupling agent solution, sufficiently stirring, drying and grinding to obtain functional powder; c. adding the functional powder to the polyurethane prepolymer, and sufficiently stirring for reacting under a nitrogen protection condition to obtain the polyurethane resin prepolymer; and d. uniformly coating base cloth with the polyurethane resin prepolymer, and conveying, rolling, coiling, shearing, sealing and bagging to obtain the medical bandage coated with the polyurethane resin prepolymer.