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Medicine composition for curing exogenous fever and process for preparing the same

A technology for exogenous heat generation and composition, which is applied in the field of preparation of oral pharmaceutical compositions and industrialized applications thereof, and can solve the problems of high import price and small output, etc.

Active Publication Date: 2006-02-15
JUMPCAN PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Antelope horns are commonly used in traditional Chinese medicine. The original animal of the genuine product on the market today is the saiga antelope. The domestic production is not large, and the import price is relatively expensive.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Prescription: forsythia 444g light tempeh 333g mint 222g nepeta 222g bupleurum 222g gardenia (fried) 189g rhubarb 189g artemisia annua 333g red peony 222g betel nut 167g magnolia 333g baicalin 333g pinellia 333g licorice 189g

[0046] Preparation method of granules: Take forsythia, peppermint, nepeta and Bupleurum four medicinal materials according to the prescription, and extract volatile oil for 3 hours with conventional steam distillation. According to the weight ratio of 1 ml of volatile oil, 10 g of β-cyclodextrin is used to inclusion the extracted volatile oil. According to the ratio of 1 gram of β-cyclodextrin to 6 ml of water, add β-cyclodextrin to water, heat and stir at 60°C to dissolve, and make a clear aqueous solution of β-cyclodextrin, let it cool to 40-50°C, Placed in a three-necked flask with stirring. After mixing 1 ml of volatile oil with 8 ml of 60% ethanol, the ethanol solution of volatile oil was prepared, and slowly dropped into the aqueous soluti...

Embodiment 2

[0050] Prescription: Forsythia 300g light tempeh 300g mint 100g Nepeta 100g Bupleurum 100g Gardenia (fried) 100g rhubarb 100g Artemisia annua 300g red peony 100g betel nut 100g Magnolia officinalis 300g Scutellaria baicalensis 300g and a half Summer 300 grams of licorice 100 grams.

[0051] Tablet preparation method: take peppermint, forsythia, nepeta and Bupleurum to extract volatile oil for 4 hours by steam distillation. According to the weight ratio of 1 ml of volatile oil, 10 g of β-cyclodextrin is used to inclusion the extracted volatile oil. According to the ratio of 1 gram of β-cyclodextrin to 6 ml of water, add β-cyclodextrin to water, heat and stir at 60°C to dissolve, and make a clear aqueous solution of β-cyclodextrin, let it cool to 45°C, and place In a three-necked flask with stirring. After mixing 1 ml of volatile oil with 8 ml of 60% ethanol, the ethanol solution of volatile oil was prepared, and slowly dropped into the aqueous solution of β-cyclodextrin under...

Embodiment 3

[0053] Prescription: Forsythia 500g light tempeh 400g mint 300g Nepeta 300g Bupleurum 300g gardenia (fried) 200g rhubarb 200g Artemisia annua 400g red peony 300g betel nut 200g Magnolia officinalis 400g Scutellaria baicalensis 400g and a half Summer 400 grams of licorice 200 grams.

[0054]Preparation method of dispersible tablet: extract volatile oil from peppermint, forsythia, nepeta and Bupleurum by steam distillation for 2 hours. According to the weight ratio of 8 g of β-cyclodextrin in 1 ml of volatile oil, the extracted volatile oil was included. According to the ratio of 1 gram of β-cyclodextrin to 4 ml of water, add β-cyclodextrin to water, heat and stir at 60°C to dissolve, and make a clear aqueous solution of β-cyclodextrin, let it cool to 50°C, and place In a three-necked flask with stirring. After mixing 1 ml of volatile oil with 6 ml of 70% ethanol, the ethanol solution of volatile oil was prepared, and slowly dropped into the aqueous solution of β-cyclodextrin ...

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Abstract

The invention provides a medicinal composition for treating exogenous fever and process for preparation, wherein the composition is prepared mainly from capsule of weeping forsythia, prepared soybean, mentha, Schizonepeta tenuifolia, Bupleurum root, cape jasmine, rhubarb horsetails, sweet wormwood, radix paeoniae rubrathe, areca-nut, magnolia bark, baikal skullcap root, pinellia tuber and licorice root.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating exogenous fever and a preparation method thereof, in particular to an oral pharmaceutical composition for treating children with exogenous fever and an industrially applicable preparation method thereof. Background technique [0002] Exogenous fever is a common disease, especially in infants and young children, and its incidence rate accounts for the first place in pediatric diseases. The characteristics of children with fever due to exogenous pathogenic factors are that their parents dote on them, often overeating fat, sweet and raw cold, resulting in impaired spleen and stomach transportation and transformation, food stagnation and internal stagnation, stagnation and heat transformation, and strong yang energy. Heat produces fire and produces phlegm, which is a syndrome of wind-heat exogenous pathogenesis and internal injury food stagnation. When wind-heat occurs, the pathogenic fact...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61K9/08A61K9/10A61K9/16A61K9/20A61K9/48A61P29/00A61P31/00
Inventor 曹龙祥
Owner JUMPCAN PHARMA GRP
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