1578 results about "High grade fever" patented technology

A multi-layer structure containing an evenly dispersed super absorbing polymer to be used for fabric covered cooling, wetting, and fire deterrent applications. Such multi-layer structure incorporates a laminate super-absorbing polymer within various layers and pockets to maintain an even distribution of super-absorbing polymer within the fabric layers. Various applications such as cooling neckbands, fever reducing suits, house-covering fire deterrent blankets and other personal cooling devices are disclosed.

The invention is directed to compositions comprising a nanoparticulate acetaminophen composition, or a salt or derivative thereof, having improved bioavailability. The nanoparticulate acetaminophen particles of the composition have an effective average particle size of less than about 2000 nm and are useful in the treatment of aches and pain, and in the reduction of fever and related conditions.

A wearable article including a fever indicator disposed on at least a portion of the article for indicating the body temperature of a wearer. The fever indicator may be used in conjunction with a disposable absorbent article and provides a signal indicating qualitative or quantitative information about the body temperature of the wearer based on the temperature of the wearer's urine.

The invention discloses a health-care electronic cigarette liquid for medical use, which mainly comprises: 3-5%w / v of tobacco leaf extract, 40-50%w / v of propanediol, 10-15%w / v of pure water, 3-5%w / v of tobacco essence, 0.2-1.0%w / v of stabilizer, 3-8%w / v of thickener, 15-20%w / v of medicament. Because of no harm of second-hand smoke, the invention can be used at public places without influence to body health of others. The invention is capable of treating cough, hacking cough, itchy throat, abundant expectoration, sensitive cough cause by acute upper respiratory tract infection of fever, influenza or the like while enjoying smoking, having treatment function to oral therapy, cough relieving, nasal and pharyngeal mucosa congestive swelling relieving and sneezing.

Astaxanthin is a potent antioxidant, over 500 times more powerful than Vitamin E and 10 times stronger than other carotenoids such as zeaxanthin, lutein, canthaxanthin and beta-carotene. Astaxanthin has also been shown to enhance and modulate the immune system and diminish the damaging effects of UVA sunlight. Disclosed is a method for retarding and ameliorating fever blisters (cold sores) and canker sores. The method comprises administering a source of astaxanthin in a therapeutically effective amount to prevent, retard and ameliorate fever blisters and canker sores. The astaxanthin may be administered orally, topically, or in a combination of oral and topical dosage.

The invention relates to a traditional Chinese medicine mixture for treating livestock and poultry virosis and a preparation method thereof. The traditional Chinese medicine mixture contains the contents according to the parts by weight: 10-40 of radix isatidis, 10-40 of folium isatidis, 7-20 of honeysuckle, 3-9 of radix bupleuri, 1-6 of radix lithospermi, 5-20 of forsythia, 5-20 of scutellaria baicalensis, 3-9 of lightyellow sophora root, 2-7 of coptis chinensis, 4-11 of raidx astragali and 1-6 of liquorice. The traditional Chinese medicine mixture has reasonable compositions, convenient mixture taking, obvious effects and no mixture residues, conforms to the safe requirement of animal-derived foods and can be effectively applied to preventing and curing the infective livestock and poultry virosis of chicken flu, newcastle diseases, duck hepatitis viruses, swine fever, virus diarrhea, and the like. The traditional Chinese medicine mixture has the advantages of low cost, simple preparation process and no environmental pollution and is suitable for industrial production.

The invention relates to a capsule for forcedly improving the immunity, which is a capsule formulation prepared by traditional Chinese medicines of parasites detoxifying and destroying type, heat dry dampness clearing, detoxifying and blood cooling type, cough and asthma relieving and phlegm reducing type, temperature cooling and exterior relieving type, kidney warming and yang enhancing type, health building type, resolving damp with aromatics and blood enriching type, qi invigorating type, spleen and stomach strengthening and interior warming type, invigorating blood circulation by removing blood stasis type, liver soothing and qi regulating type, yin tonifying and converging type, digestion helping type, liver clearing, vision helping and resuscitation inducing type, deswelling and pain stopping type, heart nourishing as well as fever reducing and fire purging type according to a certain preparation method. The capsule has the functions as follows: forcedly improving the immunity, clearing away heat and toxic material, detoxifying and destroying parasites, soothing the liver and regulating qi, invigorating blood circulation by removing blood stasis, building health, invigorating qi and enriching blood, regulating qi and stopping pain, inducing diuresis and excreting dampness, eliminating phlegm, relieving cough and asthma, warming kidney and enhancing yang, invigorating the spleen and stomach and the like. The capsule has effects for various headaches, dizzy and neurasthenia, and various intestinal tract diseases, abdominal pains and abdominal distension, and various waist and leg pains and various tumors, and can cure diseases when in ill, build body when not in ill, and can achieve the goal of healthy and long life if the long-term or discontinuous taking is carried out.

The invention relates to an alcohol-detoxication inflammation-relieving liver-protection beverage and a preparation method thereof. The beverage is prepared by taking radix puerariae, pueraria flower, citrus trifoliate, honeysuckle, chrysanthemum, rhizoma zingiberis recens and glucose as raw materials and refining and processing the raw materials by extraction technology. The beverage balances and integrates the functions of alcohol-detoxication, fever reduction, inflammation or internal heat relieving, and liver detoxification promotion, can effectively relieve bad symptoms of headache, thirst, excessive internal heat, gastric distress, and the like caused by alcoholism after a person drinks too excessively, and has obvious protection functions for livers. The invention can be prepared into liquid drink and solid drink as well.

The invention discloses an ointment used for reinforcing spleen and promoting digestion, which solves the problem that ointment is lacked in treatment of indigestion for the moment. The ointment is prepared by following steps: herbal raw materials, such as atractylis ovata, tuckahoe, medicated leaven, white paeony root, wheat germ, rhizoma cyperi, angelica, fructus aurantii immaturus, etc., are soaked in balm and fried, filtered to make medicinal oil and then the medicinal oil is added with pellets to continue decocting to obtain the ointment. The ointment of the invention is mainly used for treating indigestion, vomiting, infantile indigestion, abdominal distension, diarrhea, bellyache, malnutritional stagnation and other diseases, which are caused by adynamic fever of the spleen and stomach.

The present invention is directed to therapeutic methods using antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat cachexia, fever, weakness and / or fatigue in a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level. In another preferred embodiment, the patient's survivability or quality of life will preferably be improved.

The invention discloses an oil-in-water type vaccine adjuvant as well as a preparation method and application thereof. The oil-in-water type nano-emulsion vaccine adjuvant comprises the following components in percentage by mass: 0.1-10 percent of oil phase, 0.1-10 percent of emulsifier, 0.1-3 percent of stabilizer, 0.1-3 percent of complexing agent and 0.01-10 percent of immunopotentiator. The preparation method comprises the following steps: (1) uniformly dispersing the immunopotentiator, the stabilizer and the complexing agent in water, thereby obtaining an aqueous phase; (2) mixing an oil phase and an emulsifier, thereby obtaining an oil phase; (3) slowly adding the oil phase into the aqueous phase, and continuously stirring, thereby forming a stable emulsion; (4) regulating the pH value of the emulsion, and fixing the volume to obtain a primary emulsion; and (5) performing high-speed shearing and high-pressure homogenizing on the primary emulsion. The vaccine adjuvant provided by the invention is simple in preparation, convenient to use and small in side reactions, is used for diluting vaccines, particularly swine fever live vaccines and is high in stability and good in immune effect.

The present invention relates to novel inhibitors of glutaminyl cyclase and combinations thereof for the treatment of neuronal disorders, especially Alzheimer's disease, Down Syndrome, Parkinson disease, Chorea Huntington, pathogenic psychotic conditions, schizophrenia, impaired food intake, sleep-wakefulness, impaired homeostatic regulation of energy metabolism, impaired autonomic function, impaired hormonal balance, impaired regulation, body fluids, hypertension, fever, sleep dysregulation, anorexia, anxiety related disorders including depression, seizures including epilepsy, drug withdrawal and alcoholism, neurodegenerative disorders including cognitive dysfunction and dementia.

The invention discloses a fever epidemic situation monitoring and traceability cloud management system and method. According to the system, the identity of a detected object is recognized by a camera,a temperature measurement sensor is used to quick detect the body temperature, the body temperature data are transmitted to a cloud management server, and the data are saved to a corresponding detected object database; the associative group attributes of the detected object pre-stored in the cloud management server are used at the same time to detect all detected objects under the same associative group attributes, the number change condition of detected objects whose body temperatures exceed a set body temperature alarming threshold is counted, the state of the fever epidemic situation is thus quickly screened and judged, and corresponding help is provided for subsequent epidemic situation monitoring, traceability and control. According to the fever epidemic situation monitoring and traceability cloud management system and the method provided in the invention, the technical problem that the epidemic situation can only be known after the epidemic situation outbreaks in the prior art,epidemic situation control is not easy, communicable disease carriers can not be judged accurately, and the monitoring is caused not to be accurate can be overcome.

Methods and compositions containing bicifadine are provided for the treatment and prevention of hyperthermia in mammalian subjects. The methods and compositions may be used to prevent or treat fever, pyresis, menopausal hot flashes; peri menopausal hot flashes, postmenopausal hot flashes, hot flashes caused by anti-estrogen therapy, hot flashes secondary to surgical removal of estrogen producing tissue, hot flashes caused by radiation therapy, malignant hyperthermia, serotonin syndrome, heat stroke, febrile seizures, and neuroleptic malignant syndrome, among other conditions. Additional compositions and methods are provided employing bicifadine to treat pyresis and simultaneously elicit an analgesic response in mammalian subjects. Yet additional compositions and methods are provided which employ bicifadine in combination with a second antipyretic agent, a second analgesic agent, or a different therapeutic agent to yield more effective antipyretic treatment tools, and / or dual activity therapeutic methods and formulations useful to prevent or reduce hyperthermia and one or more additional symptoms (e.g., pain, or depression) in mammalian subjects.

The present invention provides a pharmaceutical composition comprising an aqueous solution of arginine and ibuprofen, wherein the molar ratio of arginine to ibuprofen is less than 1:1, as well as a method of making the same. The present invention also provides a method of treating a condition chosen from pain, inflammation, fever, and / or other conditions alleviated by ibuprofen comprising administering a pharmaceutical composition comprising an aqueous solution of arginine and ibuprofen, wherein the molar ratio of arginine to ibuprofen is less than 1:1.

A device and method for providing body cooling for treating fever. The cooling device applies cooling to blood flowing in a vein or artery, e.g., the vena cavae, that is then distributed throughout the body.

The technology provides an external device for estimating a core body temperature of a human subject, and a system for use in a local area, such as a school, hospital, workplace, and the like. The wrist monitor device includes a casing sized and shaped to fit onto a wrist of a human subject. The casing has a first face and a second face. In addition there is a cavity in the casing that houses a heat trap. The heat trap has an opening oriented to receive incoming thermal energy and a shell of a thermal-insulation material that has an inner thermal energy-reflective surface. Detected temperature data is compiled in a database and used to estimate whether an identified individual has a core body temperature indicative of a fever. There is also provided a system for identifying persons and screening the persons for a febrile condition. The system may include the steps of: identifying a person using data input by the individual or detected from indicia of the person and previously stored data about the person; detecting a temperature condition of the person; determining whether the person has a febrile condition using the detected temperature condition and previously stored temperature data of the person; and taking action to restrict ingress, deny ingress or allow ingress, based on the determined febrile condition of the person requiring ingress.

The invention provides a medicine preparation for clearing away heat and toxic material, which is composed of following Chinese traditional medicine materials: radix isatidis, chrysanthemum, mulberry leaf, mint, moutan bark, Chinese thorowax root, reed rhizome, cicada ecdysis, taraxacum, gypsum, dried orange peel, leaf of common perilla, cassia seed, rice, magnolia officinalis, figwort, Chinese wolfberry, rhizoma anemarrhenae, forsythia, liquorice, selfheal, gardenia and radix sileris; according to Chinese broad and wide traditional medicine theory and finely selected more than 20 Chinese traditional medicines and made through repeated clinical experiments, the medicine has the curative effects of heat-clearing and fire-purging and removing toxin for detumescence; and the medicine is used for swelling and pain in throat, swelling and pain in gum, constipation, fever heat, thirst, abdominal distention and red tongue caused by inner heat; thus having fine social effects and economical benefits through popularizing widely.

The invention discloses a method for producing a live swine fever vaccine by using a cell line. The present invention comprises the following technical steps: (1) selecting a cell line as the cells for making seedlings; (2) subculture and cultivation of cells for making seedlings; (3) breeding of cytotoxic species; (4) breeding of venom for making seedlings; 5) Mixing seedlings, subpackaging and freeze-drying. The invention has the advantages of simple and stable production process, easy operation, high virus content, small difference between batches, easy quality control, and can significantly improve the yield and quality of vaccines. The live swine fever vaccine produced by the invention has good safety and high immune efficacy, and has complete immune protection against the virulent attack of swine fever.

We have generated novel molecularly marked FMDV A24LL3DYR and A24LL3BPVKV3DYR vaccine candidates. The mutant viruses contain a deletion of the leader coding region (LL) rendering the virus attenuated in vivo and negative antigenic markers introduced in one or both of the viral non-structural 3Dpol and 3B proteins. The vaccine platform includes unique restriction endonuclease sites for easy swapping of capsid proteins for different FMDV subtypes and serotypes. The mutant viruses produced no signs of FMD and no shedding of virulent virus in cattle. No clinical signs of disease or fever were observed and no transmission to in-contact animals was detected in pigs inoculated with live A24LL3DYR. Cattle immunized with chemically inactivated vaccine candidates showed an efficacy comparable to a polyvalent commercial FMDV vaccine. These vaccine candidates used in conjunction with a cELISA provide a suitable target for DIVA companion tests.

A kit that is useful for relieving humans, and in particular infants, from discomfort is disclosed. Examples of such discomfort include fever, pain, congestion, skin irritation, and irritability. The kit includes an inner container having a plurality of compartments and at least one product for comforting humans packed in one of the compartments. Optionally, the inner container may be placed inside of an outer container.

The externally applied plaster for treating infantile fever is developed on the infantile physiological and pathological characteristics and fever cause and is prepared with 18 kinds of Chinese medicinal materials, including sweet wormwood, eucalyptus leaf, mint, schizonepta, etc. and through decoction, concentration, crushing, mix and other steps. It has the functions of dispelling wind and other pathogenic evil, clearing away heat and toxic material, resolving stagnation and alleviating mental depression, is used to treat infantile fever diseases, and has obvious curative effect and high safety.

The invention relates to a vaccine production technology in the technical field of biology, in particular to a CHO cell strain which is established by utilizing a gene engineering means and is used for expressing recombinant protein PigFC-pigSCFVE2, and a preparation method and application of the recombinant protein. The recombinant fusion protein PigFC-pigSCFVE2 provided by the invention is A1) or A2) shown as follows, wherein A1) is protein of which the amino acid sequence is as shown in SEQ ID No.2, and A2) is protein which is obtained by substituting, losing and / or adding one or several amino acid residues in the amino acid sequence of the protein of the A1) and has PigFC-pigSCFVE2 activity. A monoclonal cell strain which is obtained through the method and capable of carrying out secretory expression on PigFC-pigSCFVE2 is higher in fusion protein expression quantity, fusion protein obtained through affinity separation and purification of an antibody can be combined with a monoclonal antibody, animals can be immunized, the immunity of a generated neutralizing antibody is higher than that of a present market product, the fusion protein can be used for swine classical fever preventive vaccine, and the production cost and the immunity failure loss can be reduced.

The invention discloses application of Chinese medicinal composition in preparation of medicament for treating hand-foot-and-mouth disease. The Chinese medicinal composition comprises weeping forsythiae capsule, honeysuckle flower, ephedra herb, bitter apricot seed and the like. The Chinese medicinal composition has the function of broad-spectrum anti-virus, and can effectively treat hand-food-and-mouth disease by effectively killing virus, eclipsing fever and diminishing inflammation.

The invention discloses an intelligent public health service system used for rapidly screening and managing fever endemic situations. The intelligent public health service system comprises a remote management platform, a plurality of area screening systems, and a plurality of site disposal systems in communication with the area screening systems, wherein the area screening systems carry out body temperature screening on the human bodies, confirm the abnormal human body objects with the abnormal body temperature, detect the sign data of the abnormal human body objects, and determine the key monitoring objects in the abnormal human body objects; the site disposal systems implement the regulation measures on the key monitoring objects; the remote management platform receives the abnormal human body objects, the key monitoring objects, the detected sign data, and the regulation measure recording, and carries out the tracking and statistics service. With the intelligent public health service system provided by the invention, the technical problem that in the prior art, the monitoring, detection, reporting and management for the infectious diseases of the public health areas are inconvenient is solved.

The present invention relates to derivatives of non-steroidal anti-inflammatory drugs (NSAIDs) having improved anti-inflammatory properties useful in the treatment of inflammation, pain and fever. More particularly, NSAIDs are derivatized with a hydrogen sulfide (H2S) releasing moiety to produce novel anti-inflammatory compounds having reduced side effects.

The invention provides a fever to-be-checked computer aided diagnosis method based on PET / CT images. Full-automatic analysis of the PET / CT bone images is achieved, and a doctor is assisted in diagnosing fever to-be-checked patients. Firstly, lossless interpolation of the PET images is conducted; secondly, hospital beds in the CT images are automatically removed; thirdly, full-automatic bone segmentation of the CT images is conducted; fourthly, bone segmentation is conducted on the whole-body CT images through an optimal active contour model of a CV active contour region; fifthly, after-treatment of the CT segmented images is conducted; sixthly, bone tissue information of the PET images is acquired; seventhly, bone tissue SUVs and bone tissue BSI values are acquired through calculation, wherein the SUVs of bones, marrow and bone cortices are acquired through calculation respectively, and the BSI values of the bones, the marrow and the bone cortices of the patients are acquired through calculation via the SUVs; eighthly, diagnosis is conducted based on the BSI values, wherein the SUVs and the BSI values are compared with SUVs and BSI values in an existing confirmed patient database, and a diagnosis report is made.

The invention relates to a method for producing Chinese herbal medicine health-care dark eggs. The method comprises the following steps: (1) taking bear gall powder, western safflower and the like to form a Chinese herbal medicine composition; (2) adding the above Chinese herbal medicine composition into a feed, mixing evenly and forming a mixed feed, wherein, the addition quantity is the weight ratio of 5-20:100 of the Chinese herbal medicine composition to the feed; and (3) feeding laying Taihe chicken with the mixed feed and laying eggs after feeding for 7 days, namely, the Chinese herbal medicine health-care dark eggs. The produced dark eggs contain abundant proteins, amino acids, vitamins, selenium, DHA and various famous and precious Chinese herbal medicine components, have abundant nutrition, strong medicine potency and obvious curative effect, have the effects of strengthening the spleen and the kidney, tonifying the liver, nourishing the stomach, supplementing qi, tonifying the blood, nourishing yin, reducing fever, smoothing collaterals, promoting blood circulation and the like, and have a favorable food therapy effect for preventing and treating diabetes, hypertension, hemiplegia, apoplexy sequelae, cardiovascular and cerebrovascular diseases and all classes of cancers.

The invention describes novel organic nitric oxide enhancing salts of nonsteroidal antiinflammatory drugs (NSAIDs) and novel compositions comprising at least one organic nitric oxide enhancing salt of an NSAID, and, optionally, at least one nitric oxide enhancing compound and / or at least one therapeutic agent. The invention also provides novel compositions and kits comprising at least one organic nitric oxide enhancing salt of an NSAID, and, optionally, at least one nitric oxide enhancing compound and / or at least one therapeutic agent. The invention also provides methods for (a) treating inflammation, pain and fever; (b) treating gastrointestinal disorders; (c) facilitating wound healing; (d) treating gastrointestinal, renal and / or respiratory toxicities resulting from the use of nonsteroidal antiinflammatory compounds; (e) treating inflammatory disease states and / or disorders; (f) treating ophthalmic disorders; (h) treating peripheral vascular diseases; (i) treating diseases resulting from oxidative stress; (j) treating endothelial dysfunctions; and (k) treating diseases caused by endothelial dysfunctions. The organic nitric oxide enhancing compounds that form salts with the NSAIDs are organic nitrates, organic nitrites, nitrosothiols, thionitrites, thionitrates, NONOates, heterocyclic nitric oxide donors and / or nitroxides. The heterocyclic nitric oxide donors are furoxans, sydnonimines, oxatriazole-5-ones and / or oxatriazole-5-imines.