195 results about "Blisters" patented technology

The present invention provides an inhaler comprising a housing which contains a blister strip having a plurality of blisters which contain powdered medicament for inhalation, a mouthpiece mounted to the housing through which the medicament is inhaled by a user, an indexing and opening mechanism for indexing the blister strip and for opening the blisters which is operated by an actuator, wherein the blister strip is indexed by forward motion of the actuator from a first position to a second position, such as by opening a cover, and is also indexed in the same direction by reverse motion of the actuator from the second positon to the first position, such as by closing the cover.

The present invention provides an inhaler comprising a housing which contains a blister strip having a plurality of blisters which contain powdered medicament for inhalation; a mouthpiece through which the medicament is inhaled by a user; an indexing wheel for indexing the blister strip; an opening mechanism for opening the blisters; an actuator which is movable between a first position and a second position in order to operate the indexing wheel and the opening mechanism; and a coupling mechanism for coupling the actuator to the indexing wheel so that the indexing wheel rotates together with the actuator during part of the motion of the actuator; characterized in that the coupling mechanism comprises a shuttle that rotates on the same axis as, and translates axially relative to, the indexing wheel.

A split grip sock device is disclosed that reduces slippage during lateral movements commonly performed during sports like basketball, tennis, soccer, and football. The device solves these problems by adding grip to the bottom of the sock and having a separate compartment for the big toe which allows for improved pivoting and change of direction. Further, the device also provides cushioning over the metatarsals to alleviate shoelace pressure and over the heel area to prevent blisters. Specifically, the split grip sock device comprises a thicker weave over the top of the foot and heel, with heat-pressed rubber pieces on the bottom of the sole.

A child resistant container comprising a blister and a sleeve. The blister comprises a plurality of compartments arranged radially around a centrally disposed hub. Each compartment defines a cavity for holding contents. The container is a “dial pack” type container in that the blister can be rotated with respect to the sleeve to expose each cavity in turn.

The present disclosure relates to high barrier, polyvinyl chloride (PVC) free, cold forming multilayer blisters. The laminate comprises an intermediate aluminum layer, defining an operative outer surface and an operative inner surface; at least one polyethylene polymer layer adhered to the inner surface of the intermediate layer and an oriented polyamide layer, metallized on its operative outer surface, and adhered to the operative outer surface of the intermediate layer. The MULTILAYER laminate of the present disclosure has a water vapour transmission rate (WVTR) less than 0.0035 gm / pkg / day. The multilayer laminate of the present disclosure provides a high barrier against moisture, light and gas, which enhances the overall shelf life of the product that is being packaged.

The invention discloses an alternative virus infection model capable of being used for simulating human Marburg virus disease symptoms under BSL-2 as well as an establishment method and application of the alternative virus infection model, and belongs to the technical field of biology. According to the invention, firstly, a recombinant vesicular stomatitis virus (VSV-MARV / GP) for expressing Marburg virus glycoprotein is constructed, and the VSV-MARV / GP is used as an alternative virus to cause lethal infection of a narrative hamster. The pathogenicity of the VSV-MARV / GP has species specificity, age correlation, gender correlation and attack pathway dependency. After infection of VSV-MARV / GP, female narrative hamsters of 5 weeks old show weight loss, multiple organ failure, high virus load and other symptoms and develop into serious systemic diseases similar to those observed by human MARV patients, and all animals die within two to three days after infection. The model provided by the invention can be used as an effective tool for carrying out rapid preclinical evaluation on medical countermeasures of MARV under the BSL-2 condition.

An osmotic bandage for treating wounds, such as cuts, abrasions, minor burns, blisters, and post-surgical incisions. The bandage includes a bandage strip with an adhesive along with a plurality of apertures or airholes disposed therethrough for breathability. The bandage further includes a multi-layered gauze pad. The multi-layered gauze pad includes a first layer, a second salt laced layer, and a third odor-reducing layer. The salt is a natural bactericide, through the dehydration of water in bacteria, and kills any bacteria that attempt to invade or enter the wound site. A semi-permeable membrane cover may be disposed in overlying relation to the pad to prevent the salt from being in direct contact with the wound tissue and causing the patient pain.

The invention discloses a solid-liquid separation method for low-odor water-soaked manure, which specifically comprises the following steps: acting on water-soaked manure with the water content of 80-99.9% by adopting an electrode plate with conductive and filtering effects, enabling charged large particles in the water-soaked manure to do directional movement towards one side under the action of an electric field, filtering and recovering a liquid phase through the electrode plate, and recycling the liquid phase through the electrode plate. Therefore, fine particulate matters with the particle size of more than 0.1 mu m in the blistered manure are efficiently separated in a low-odor manner; according to the method and the device disclosed by the invention, the fine particulate matters in the blister dung can be efficiently separated, the odor emission content in the treatment process is low, the content of separated liquid-phase pollutants is also greatly reduced, and the removal rates of COD, TP, ammonia nitrogen and turbidity are 75%, 80%, 20% and 90% or above.

Wearable blister card magazines, blister card transfer trays and systems, and standalone medication magazines including one or more compartments that hold respective sleeves of medication, as well as a respective blister card, are provided. The blister card(s) include blisters of medication, and the blister sleeve(s) include openings designed to align with the blisters of the blister card(s). The removal of medication from each blister may be automatically detected and digitally recorded, along with the time and the individual who removed the medication. In addition to permitting alignment of each blister on the blister card, the openings on the sleeve also permit the ejection of the medicine through the openings without being removed from the sleeve. Intelligent medication management systems configured to provide end-to-end management and monitoring for patient dosing regimens are also provided.

A blister pack having a backing having a first side and an opposing second side. Each of the first and second side is flat or planar. The blister pack can also include a cover having a first side and an opposing second side. At least a portion of the second side of the cover is adhered to the first side of the backing to form a sealed package for containing product. The cover can include at least one blister. The blister pack can also include an active member positioned within each blister. Each active member can be in the form of a ring with an opening extending therethrough or a depression formed therein.

A paper-based blister package comprising a flat card and a tray is provided. The tray comprises a bottom wall, two opposing side walls, two opposing end walls, two opposing side flanges, and two opposing end flanges. The bottom wall has a perimeter defined by two side fold lines and two end fold lines. Each side flange has at least one locking end that meets a side wall and a side flange fold line at a junction. The side flange and the side wall are contoured to define a side flange shoulder adjacent the junction. At least one end flange forms an outward projecting lip configured to engage the junction to maintain proper positioning of the side flange, the end flange, the side wall and the end wall.

A method for operating a repackaging device for repacking medications comprising transportable pill containers, each container exhibiting a receptacle compartment and either exhibiting a dispensing mechanism or an opening sealed by a foil, wherein a pill located in the compartment can be pushed out through the opening, destroying the foil, a working storage device in which some pill containers can be stored and a filling device, a packaging station, wherein a device transports a pill removed from the pill container to the station, a mixing storage area in which some pill containers and packages containing pills or blisters can be stored, a workstation for unpacking pills or blisters in packages and a supply device with which a pill container and / or package can be supplied from the mixing storage to the workstation, and / or a discharge device with which a pill container and / or a package can be supplied to the mixing storage.

The invention belongs to the technical field of label attaching, and discloses a label attaching device which comprises a first attaching module and a driving module, and the first attaching module comprises a first suction cup and a label bending module. The driving module drives the first suction cup to move between the label feeding station and the label attaching station, so that the first suction cup can suck the first label from the label feeding station and transfer the first label to the label attaching station, and in addition, the first suction cup can suck the first label from the label feeding station and transfer the first label to the label attaching station. The first suction cup and the label bending module are matched to attach the first label to the edge of the sealing position of the product, and the first label is pasted to the two intersecting surfaces forming the edge at the same time. Compared with manual labeling, the automatic labeling machine has the advantages that automation of labeling operation can be realized, so that the working efficiency of labeling operation can be improved, the production efficiency of products can be improved, and the quality problems of wrinkles / blisters and the like of the first labels attached to the products can be avoided.

An object of the present invention is to provide a solid substance, a molded article, and a method for producing the solid substance, which can form a molded article that is less likely to generate blisters due to ozone and has excellent ozone resistance. 【Solution means】The solid substance of the present invention is a powdery or pelletized solid substance containing a copolymer containing a unit A based on tetrafluoroethylene and a unit B based on a monomer selected from the group consisting of a monomer represented by the formula (1) (CF2=CF-O-(CF2) n -CF3) and a monomer represented by the formula (2) (CF2=CF-CF2-O-(CF2) n -CF3), wherein the total number of functional groups of -CF=CF2, -CF2H, -COF, -COOH, -COOCH3, -CONH2, and -CH2OH is less than 150 per 10 main chain carbons of the copolymer, and substantially does not contain a compound represented by the formula (3) (CF3-(CF2) 6 -COOH). n-1 ​

The invention provides a device for compressing hematoma of a forearm after a coronary artery operation, relates to the technical field of medical equipment, and solves the technical problem that in the prior art, uniform pressure distribution in a whole compression area is difficult to ensure in a manual bandaging process. The device for compressing the hematoma of the forearm after the coronary artery operation comprises a plate body used for supporting the arm to compress the hematoma; the at least two arc-shaped plates are oppositely and slidably arranged on the plate body and move in the width direction of the plate body; each arc-shaped plate is provided with an arc-shaped concave surface facing an arm, and the arc-shaped concave surfaces of the two arc-shaped plates are oppositely arranged; the driving assembly is connected with the arc-shaped plates and used for driving the two arc-shaped plates to get close to the extrusion arm or get away from the extrusion arm. The compression strength is controlled by adjusting the driving assembly, the occurrence of complications such as skin damage, blisters and even infection possibly caused by long-time fixed compression in traditional manual bandaging is avoided, and the extra body burden and pain of a patient are greatly reduced.

The invention discloses special feeders matched with bubble cap molds in a one-to-one mode. Comprising a bubble cap machine table board, a bubble cap machine table board track arranged on the bubble cap machine table board, a caterpillar band feeder discharging component detachably arranged on the bubble cap machine table board and located above the bubble cap machine table board track, and a caterpillar band feeder feeding component detachably arranged on the caterpillar band feeder discharging component. When the feeder is used, the reliability is high, the service life is long, and blisters can be efficiently and stably filled with medicine. The universality of the feeding mechanism can be greatly improved, and the feeding requirements of customers for various tablets are met. And universal feeding is really achieved. Servo tracking is adopted, and the speed is completely matched with a host.

To provide an inhaler device provided with medicament carriers containing individual pockets or blisters of powdered medicament covered by a lidding sheet such as lidding foil.SOLUTION: An inhaler device (701) provides a common actuator (710) for controlling movement of indexing systems (712, 714) for advancing / indexing a dose, and provides opening systems (790, 791) for opening a dose such that progression of the opening systems (790, 791) is disproportional to progression of the indexing systems (712, 714) during movement of the common actuator (710).SELECTED DRAWING: Figure 66

The invention is directed to the field of machinery for the automated dosing of drugs for therapeutic plans intended for patients, and relates to a machine (1) for the preparation of pre-dosed drug administration units, in particular of the type in the form of tablets, lozenges, capsules or the like, comprising: - means for feeding blisters (BL) of the type provided with cells (A); - a three-dimensional scanner (2), adapted to detect the shape and arrangement of the cells (A) of one of said blisters (BL); - handling means adapted to move said blisters (BL) from said feeding means towards said three-dimensional scanner; - a shear (3) adapted to separate said cell (A1) from said blister (BL) on the basis of the coordinates (X, Y) detected by said three¬ dimensional scanner (2); - a packaging unit (4), adapted to receive the cells (A) separated by said shear (3); - an electrical panel (5) and a control panel (6); a robotic arm (7) to which said shear (3) is associated, so that said shear (3) is moved towards said blister (BL) to carry out the separation, by cutting, of a single cell (A1) when the blister (BL) is positioned below said three-dimensional scanner; - said shear (3) includes a tray (8) adapted to at least partially support said blister (BL) during the cutting step and to accommodate the cell (A1) separated from said blister (BL), supporting it until it reaches the unit packaging machine (4) where it will be abandoned.

A point-of-care testing (POCT) system comprising an analyzer, a measurement cartridge, and a calibration cartridge for calibrating the measurement cartridge is described. The measurement cartridge comprises at least one electrochemical sensor for measuring the one or more properties of the blood sample, and the calibration cartridge comprises a similar at least one electrochemical sensor and at least one sealed blister containing calibration fluid for calibrating the measurement cartridge. Examples of properties of the blood sample may be pH, blood gases, electrolytes, and metabolites like glucose and creatinine. The measurement cartridge may also comprise an optical chamber for measuring for example, bilirubin and hemoglobin species, for which the analyzer comprises stored calibration algorithms. The optical chamber may be disposed in any location in the measurement cartridge, for receiving a portion of the blood sample.

Disclosed is a dry powder inhaler for delivering medicament from at least one blister pack, each blister pack having a plurality of spaced-apart blister pockets containing doses of the medicament. The inhaler comprises: a housing for accommodating unused and used portions of the at least one blister pack together with a dispensing mechanism for simultaneously opening at least two blister pockets at a time; and a manifold component through which air can be drawn in use of the inhaler. The manifold component comprises: first and second air inlet openings for receiving external air; a first air outlet opening for providing the external air to a first opened blister pocket and a first medicament inlet opening for receiving air-entrained medicament from the first opened blister pocket, the first air outlet opening and the first medicament inlet opening being arranged side-by-side to enable simultaneous communication with the first opened blister pocket; a second air outlet opening for providing the external air to a second opened blister pocket and a second medicament inlet opening for receiving air-entrained medicament from the second opened blister pocket, the second air outlet opening and the second medicament inlet opening being arranged side-by-side to enable simultaneous communication with the second opened blister pocket; and a medicament outlet opening for delivery of the air-entrained medicament from the first and second opened blister pockets to the user, the first and second medicament inlet openings being fluidly connected to the medicament outlet opening by a medicament delivery conduit formed in the manifold component. The first and second air inlet openings are fluidly connected to the first and second air outlet openings by respective first and second air conduits in the manifold component, wherein the air conduits are separately provided so that the external air from each of the first and second air inlet openings does not mix with the external air from the other of the first and second air inlet openings before reaching the first and second opened blister pockets.

The invention provides a medicine package detection device and method, and relates to the technical field of package detection. A pneumatic suction cup is arranged at the bottom of the movable seat, a pressing mechanism comprises a fixed seat, a plurality of pressing assemblies are arranged at the bottom of the movable seat and the top of the fixed seat, a detection box performs defect detection on a bubble cap medicine plate and comprises a box body, a top cover is connected with the top of the box body in a sealed mode, a detection cavity is formed in the top of the box body, and a pressure adjusting cavity is formed in the box body. The hydraulic cylinder is arranged on the side of the pressure regulating cavity, the piston assembly is arranged on a piston rod of the hydraulic cylinder and is in sliding sealing with the pressure regulating cavity, the visual detection mechanism is arranged in the detection box, the pressing assembly corresponds to the bubble cap in position, and an electric push rod is arranged on the pressing assembly at the bottom of the moving seat to drive the pressing assembly to move. The detection cavity is communicated with the pressure adjusting cavity, a pressure gauge is arranged in the detection cavity, and the pressure adjusting cavity is communicated with an air pipe. The hidden defect of the bubble cap medicine plate can be detected, and deterioration and failure of the medicine caused by bubble cap breakage in the transportation and storage process of the medicine are avoided.

A dry-powder inhaler may include a casing. The casing may include a first casing portion, a second casing portion, and a hinge arrangement connecting the first casing portion and the second casing portion. The dry-powder inhaler may be assembled via folding the first casing portion and the second casing portion together. The first casing portion may include a cavity for receiving a dose blister foil. The cavity may be adapted to contain a dry-powder medicament. The first casing portion and the second casing portion, when folded together, may define an inlet for allowing a lidding foil to extend out therefrom. The casing may further include an outlet nozzle for providing the medicament. The outlet nozzle may extend at an angle from one of the first casing portion and the second casing portion.

The present disclosure relates to multilayer, multibarrier, cold formable blister laminate. The present disclosure further relates to a compact blister pack made by cold forming of the multilayer, multibarrier, cold formable blister laminate. The laminate of the present disclosure incorporates or interlace mechanical cum impact strength enhancing materials, desiccant materials or both mechanical cum impact strength enhancing and desiccant materials. The laminate of the present disclosure has enhanced deep draw formability as well as is capable of yielding cold formed blisters of compact size along with improved mechanical and impact strength for cavities with large dimensions without any rupture after forming and at the same time providing requisite ultra high barrier with use of desiccant interlacing when required, against adverse environmental impact. The laminate of the present disclosure can be used for packaging of various products having large dimensions and which are fragile as well as sensitive or highly sensitive to moisture, temperature, and light.

The present invention relates to inhaler devices (701), and in particular to devices provided with medicament carriers containing individual pockets or blisters of powdered medicament covered by a lidding sheet such as a lidding foil. A common actuator (710) is provided for controlling movement of an indexing system (712,714) for advancing / indexing a dose and an opening system (790,791) for opening a dose such that progression of the opening system (790,791) is disproportional to progression of the indexing system (712,714) during movement of the common actuator (710).

The invention discloses a traditional Chinese medicine preparation for treating herpes pain and itch as well as a preparation method and application of the traditional Chinese medicine preparation, and belongs to the technical field of traditional Chinese medicines. 30 to 45 parts of paniculate swallowwort root; 25-35 parts of lithospermum erythrorhizon; 25 to 35 parts of sedum sarmentosum; and 8-12 parts of borneol. The traditional Chinese medicine preparation for treating herpes pain and itching is reasonable in formula, simple in raw material components and low in cost, has the effects of clearing heat, promoting diuresis, detoxifying, cooling blood, relieving itching and pain, and has obvious anti-inflammatory, analgesic and itching-relieving effects; the traditional Chinese medicine is used for treating heat sores caused by excessive lung and stomach heat and liver and gallbladder damp-heat syndromes, can effectively treat pruritus and pain caused by herpes, and is quick in effect and remarkable in curative effect; the traditional Chinese medicine composition can be used for preventing and treating itching and pain caused by herpes zoster and pain and itching of postherpetic nerves, and has a good prevention and treatment effect; the traditional Chinese medicine composition is safe, free of toxic and side effects, free of drug resistance, simple in preparation method and wide in application prospect.

The invention discloses a blister tray feeding and discharging device and a packaging production line, and relates to the technical field of feeding device tray feeding and discharging. The bubble cap feeding and discharging mechanism is used for supplying the bubble caps to the bubble cap transferring mechanism and recycling the bubble cap trays. Through automatic lifting of the object carrier, automatic clamping and pushing of the limiting clamping plate and automatic transferring of the second-stage conveying frame, ordered circulation of tray feeding, bubble cap transferring and tray recycling is achieved, full-process semi-automation of bubble cap supplying and tray recycling is achieved, frequent manual intervention is not needed, and the production efficiency is improved. Operators only need to be responsible for material supplement, equipment inspection and finished product collection, and do not need to participate in high-strength and repeated manual transfer, putting and other operations, so that the production efficiency is greatly improved, the labor intensity is greatly reduced, meanwhile, direct contact between workers and materials is reduced, the drug pollution risk is reduced, the production operation environment is improved, and the production cost is reduced. The clean production requirement of the pharmaceutical industry is met.

The utility model discloses a heat sealing machine for blister blister packaging, which comprises a turntable and an L-shaped baffle plate, and the top of the turntable is fixedly connected with the L-shaped baffle plate; the flexible replacement assembly comprises a rectangular baffle, a strip-shaped groove and a strip-shaped rod, the strip-shaped groove is formed in the L-shaped baffle in a penetrating mode, the side portion of the rectangular baffle is fixedly connected with the strip-shaped rod, and the strip-shaped rod movably penetrates through the strip-shaped groove in a penetrating mode; the flexible replacement assembly further comprises half-shaped check blocks, a first external connection plate and a second external connection plate, the L-shaped baffle and the rectangular baffle are movably connected with the half-shaped check blocks, and the first external connection plate and the second external connection plate are movably connected between the half-shaped check blocks. According to the plastic uptake blister packaging device, the space for containing the plastic uptake blisters can be adjusted, then the plastic uptake blisters of two different sizes can be packaged, the purpose that the plastic uptake blisters of two different specifications can be produced through one structure is achieved, and the universality and economical efficiency of the device are improved.

The application discloses digital mold positioning dry particle ceramic tiles with reduced pimple and pinhole and a preparation method thereof, and the method comprises the following steps: A, a blank is formed by rolling and molding, and a body is obtained after first drying; B, mold ink and digital face glaze are printed on the surface of the body in sequence, and a digital mold layer is obtained after second drying; C, oily protective glaze ink is printed on the surface of the digital mold layer to obtain a moisture isolation layer; D, positioning glue and positioning dry particles are printed on the surface of the moisture isolation layer in sequence, and a positioning dry particle layer is obtained after third drying; E, protective glaze is sprayed on the surface of the positioning dry particle layer, and digital mold positioning dry particle ceramic tiles are obtained after fourth drying, firing and polishing in sequence. The scheme can effectively solve the problem of difficult exhaust caused by large thickness of the positioning dry particle layer and large number of dry particles, and improve the pimple and pinhole defects on the surface of the ceramic tiles, so as to overcome the shortcomings in the prior art.

The invention provides a non-adhesive hydrogel patch for skin wounds as well as a preparation method and application of the non-adhesive hydrogel patch, and belongs to the technical field of medical dressings. The non-adhesive hydrogel application comprises a wound contact layer and an absorption layer which are sequentially arranged in a stacked mode. Wherein the wound contact layer is composed of a bacteriostatic hydrogel cushion layer and a reinforcing layer, and the bacteriostatic hydrogel cushion layer is composed of poly (sodium acrylate-co-acrylamide) composite hydrogel and a bacteriostatic agent; the reinforcing layer is a non-woven fabric composed of carboxymethyl cellulose or alginate fibers; the absorption layer is formed by combining a semi-permeable membrane and a substrate, and the semi-permeable membrane is a cellulose acetate semi-permeable membrane coated with anionic polyacrylamide hydrogel. The non-adhesive hydrogel application disclosed by the invention has a bacteriostatic agent three-stage slow-release effect, has more stable and lasting bacteriostatic performance, and has the effects of unidirectional water passing and wound seepage absorption, and realizes rapid and efficient repair of wound surfaces such as skin erosion, debonding, necrosis, blisters, skin trauma and the like in a wet surface environment.