324 results about "Lipophilicity" patented technology

The invention discloses a lipophilic liposome containing polydeoxyribonucleotide as well as a preparation method and application of the lipophilic liposome. The lipophilic liposome comprises the following components in parts by weight: 0.001-3 parts of polydeoxyribonucleotide; 0.5 to 3 parts of phospholipid; 0.1-2 parts of a cationic emulsifier; 0.1-3 parts of an anionic emulsifier; 40 to 70 parts of polyol; the total amount is 100 parts. According to the invention, an emulsifier system formed by combining lecithin with anionic and cationic compound surfactants is adopted, so that the transdermal absorption of PDRN is facilitated. The lipophilic liposome containing polydeoxyribonucleotide prepared by the invention can effectively resist nuclease degradation, prolong the acting time of PDRN in skin, and improve the skin anti-aging and repairing effects of the liposome. The anti-aging effect of the active ingredients is improved, and the bioavailability of the active ingredients is improved. The cosmetic composition can be widely applied to cosmetic formulas of various dosage forms.

The invention relates to the technical field of materials, in particular to preparation of an amphiphilic tungsten disulfide nano material and application of the amphiphilic tungsten disulfide nano material in preparation of an oil displacement agent. The oil-displacing agent prepared from the amphiphilic tungsten disulfide nano material can reduce the interfacial tension of an oil-water interface, and can be quickly adsorbed to the oil-water interface to layer oil and water; the surface wettability of the rock is changed, the lipophilicity of the rock is changed into weak hydrophilicity, and the pore throat cannot be blocked due to excessive hydrophilicity while the oil phase is stripped. The nano oil-displacing agent disclosed by the invention can still have an enough stable use effect after being frozen at a low temperature and then unfrozen.

The invention discloses a surface lipophilic modified barite weighting material as well as a preparation method and application thereof, and belongs to the technical field of drilling fluids. The surface lipophilic modified barite weighting material comprises barite and a surface modifier, and the surface modifier comprises a copolymer formed by polymerizing a monomer A, a monomer B, a monomer C and a monomer D. According to the invention, the lipophilicity of the barite is chemically modified by the surface modifier, and all monomers have a synergistic effect, so that when the grafted and modified barite weighting material is used as the weighting agent of the oil-based drilling fluid, the dispersity and the stability of particles in the oil-based drilling fluid can be improved, and the rheological property, the plugging property and the high-temperature resistance of the drilling fluid can be adjusted.

The invention relates to the technical field of packaging materials, in particular to a manufacturing method of an industrial byproduct semi-hydrated gypsum hollow plastic plate. The plastic plate is prepared from the following components in parts by weight: 60 to 70 parts of superfine modified semi-hydrated phosphogypsum powder, 28 to 35 parts of polypropylene resin, 0.5 to 1.5 parts of slipping agent, 0.5 to 1.5 parts of dispersing agent, 0.5 to 1.5 parts of antistatic agent, 0.3 to 0.8 part of antioxidant, 5 to 10 parts of calcium oxide and 3 to 6 parts of polyolefin elastomer. The gypsum powder subjected to purification, calcination and quaternary ammonium / stearic acid surface treatment has oleophylic and hydrophobic properties, and 65% high-proportion filling can be realized; the light moisture-proof plate with the density of 0.75-0.95 g / cm < 3 > and the thickness of 3-6 mm is obtained by matching with a double-screw granulation process and a single-screw hollow plate extrusion process, the use amount of resin is reduced, the mechanical property and the heat resistance are obviously superior to those of a single surface modifier, and high-value utilization of ardealite resources is realized.

Disclosed in the present disclosure are a bio-based organic silicon surfactant, and a preparation method therefor and the use thereof. The surfactant has the following structure: Si(CH3)3-O-[Si(CH3)2-O]a-[Si(CH3)R1-O]b-[Si(CH3)R2-O]c-Si(CH3)3. By using a comb-shaped structure with a hydrophobic siloxane as a main chain and a hydrophilic polyether as a side chain, a bio-based substance is grafted and introduced to the polyether at the side chain thereof by means of an epoxide ring-opening reaction, thereby adjusting the hydrophilicity and lipophilicity of the organic silicon surfactant to a certain extent and improving the surface activity of the organic silicon surfactant. The introduction of the bio-based substance can reduce the heat conductivity coefficient of polyurethane foam, increase the flow index of the polyurethane foam and improve the heat insulation performance and flowing performance of the foam. In addition, the synthesis of the organic silicon surfactant provides a new synthesis route for the development of a bio-based foam stabilizer; and the preparation method is simple, easily operated and suitable for industrial production.

The present invention relates to new salt forms of sabcomeline. The new salt forms are lipophilic acid salts of sabcomeline wherein the lipophilic acids used to prepare the new salts may have a Hansen solubility parameter distance from water of at least 20.7. The present invention also relates to new crystalline forms of sabocomeline salts.

The object of this invention is a lipophilic activity modifier in the form of dimethyl sulfone (MSM) for use as a transdermal penetration enhancer for high molecular weight active substances with a molecular weight (Mw) > 500 Da. Another object of this invention is a cosmetic composition for transdermal application comprising an active substance and a transdermal penetration enhancer, characterized in that the active substance is encapsulated by the transdermal penetration enhancer, which is the lipophilic activity modifier according to claim 1, and the active substance is a high molecular weight active substance with a molecular weight (Mw) > 500 Da. Another object of the present invention is a method for preparing a composition according to the invention, characterized in that the method is carried out by thermal emulsification or cold emulsification, wherein thermal emulsification comprises the following steps: a) mixing dimethyl sulfone and a diluent in a reaction vessel; b) bringing the mixture to 70-85°C; c) stirring the mixture at 70-85°C; the start of homogenization depends on the stage of phase combination; d) cooling the mixture to 20-40°C, preferably 30°C; e) adding a high molecular weight active substance with Mw>500 Da and homogenizing the mixture, preferably for 1-3 min; while cold emulsification comprises the following steps: a) mixing dimethyl sulfone and a diluent in a reaction vessel and dissolving at a temperature maintained at 20-25°C; b) bringing the mixture to a temperature of 15-35°C, preferably ambient temperature or 25°C; c) stirring the mixture at a temperature of 15-80°C, preferably 25°C; the start of homogenization depends on the stage of phase combination; d) adding a high molecular weight active substance with Mw>500 Da and homogenizing the mixture, preferably for 1-3 min.

A topical neurocosmetic composition comprising a first component including one or more of bakuchiol, allantoin, squalane, or Morinda citrifolia extract; a second component including one or more of hyaluronic acid, vitamin E, Zanthoxylum alatum fruit extract, Coriandrum sativum seed oil, Vitex agnus-castus extract, Helianthus annuus sprout extract, niacinamide, resveratrol, or an ascorbyl ester; and a cosmetically acceptable oil-in-water vehicle configured to deliver both lipophilic and hydrophilic actives through the skin to dermal neurons. The composition improves measurable skin parameters such as hydration and elasticity and supports psychophysiological comfort. Methods of manufacture and use are also described

A lipophilic derivative of an aminopolycarboxylic acid may be used as an extractant to extract at least one rare earth from an acidic aqueous solution. Such a lipophilic derivative may be applied to the production of rare earths from concentrates derived from urban ores and, in particular, from concentrates from waste electrical and electronic equipment such as used or discarded NdFeB permanent magnets. Such a lipophilic derivative may be used in producing rare earths from concentrates derived from natural ores or from concentrates derived from residues of natural ores.

The application provides a drying method of Chuanxiong medicinal material and application of Chuanxiong or its extract in preparation of an external medicine for treating atopic dermatitis. The drying method of Chuanxiong medicinal material improves Chuanxiong processing efficiency, shortens processing period, obtains by-product Chuanxiong extract in addition to preparation of decoction pieces, reduces energy consumption and lowers production cost. The Chuanxiong essential oil and Chuanxiong extract are both composed of small molecule components, have good affinity to skin, are absorbed through skin quickly, can quickly relieve symptoms such as itching and skin damage caused by atopic dermatitis, and are natural, safe and free of side effects. Meanwhile, the small molecule components contained in the Chuanxiong essential oil and Chuanxiong extract have good lipophilicity, have softening effect on the thickened stratum corneum caused by atopic dermatitis, and are more conducive to drug absorption. In addition, the Chuanxiong essential oil and Chuanxiong extract are simple to prepare and low in price.

The invention discloses a solution immersion type fingerprint detection method based on AIEgens, which comprises the step of carrying out immersion type fluorescent fingerprint detection based on the aggregation-induced emission effect of an organic fluorescent compound TPP-APBP-P. TPP is used as a luminous substrate, a long chain is connected to the luminous substrate to improve the lipophilicity of the luminous substrate, TPP-APBP-P is obtained, meanwhile, the PH of a solution is adjusted to improve the hydrophilicity of the luminous substrate, and finally the detection effect of the luminous substrate on potential fingerprints is improved; the fingerprint detector has very excellent detection effects on fingerprints in a high-temperature environment and aged fingerprints, and has high contrast, high sensitivity and high precision on fingerprint development.

COMPOSITION COMPRISING INORGANIC UV FILTERS The present invention relates to a composition comprising: (a) at least one first inorganic UV filter selected from hydrophilic inorganic UV filters; and (b) at least one second inorganic UV filter selected from (b1) amphiphilic inorganic UV filters, (b2) lipophilic inorganic UV filters, and mixtures thereof, the weight ratio of the quantity of (a) first inorganic UV filter(s) / the quantity of (b1) amphiphilic inorganic UV filter(s) in the composition being from 10:1 to 1:10, and the weight ratio of the quantity of (a) first inorganic UV filter(s) / the quantity of (b2) lipophilic inorganic UV filter(s) in the composition being from 10:1 to 1:8.The composition according to the present invention can offer at least an acceptable user experience, preferably in terms of a pulling sensation, a sticky sensation, a fresh sensation and a greasy sensation. Figure for the abstract: none.

The invention discloses a liquid-liquid coalescence filter element material for oil dehydration, which takes glass fiber paper as a substrate and is coated with the following modified materials in percentage by mass: 1 to 5 percent of nano silicon dioxide, 2 to 10 percent of gamma-aminopropyltriethoxysilane, 2 to 10 percent of octadecyltriethoxysilane and the balance of absolute ethyl alcohol. The water contact angle of the liquid-liquid coalescence filter element material is larger than 150 degrees, and the oil contact angle is smaller than 10 degrees; the invention also discloses a preparation method which comprises the following steps: uniformly mixing the raw materials to form a modified solution, spraying the modified solution on the surface of the cured glass fiber paper, and drying to obtain the liquid-liquid coalescence filter element material. According to the invention, the nano silicon dioxide is modified by gamma-aminopropyltriethoxysilane and octadecyltriethoxysilane, so that the super-hydrophobicity and super-lipophilicity of the glass fiber paper are improved; the prepared liquid-liquid coalescence filter element material is uniform and firm in coating adhesion and suitable for the fields of oil product production, storage, transportation and the like.

The present application relates to an antifungal microneedle patch and its preparation method and application, the antifungal microneedle patch includes backing layer and the needle head arranged on the surface of the backing layer;The needle head constitutes n×n array on the surface of the backing layer;The surface of the needle head includes fatty acid coating containing antibacterial drug;The inside of the needle head includes photosensitizer;The n is selected from integer.The antibacterial drug is lipophilic triazole antifungal drug.The fatty acid is selected from saturated fatty acid containing 6-12 carbon atoms.The present application innovatively combines antifungal drug itraconazole and photo-thermal agent / photosensitizer indocyanine green, loads in microneedle, can carry out painless minimally invasive local administration, through the antibacterial action, photo-thermal effect and photodynamic effect of antifungal drug released under the excitation of near-infrared light, realize the effective killing to fungi, and will not cause irreversible damage to normal tissue.

The present invention relates to a cosmetic composition in the form of a water-in-oil (W / O) emulsion, comprising a continuous fatty phase comprising at least one hydrocarbon oil with a refractive index greater than equal to 1.4, an aqueous phase dispersed in the continuous fatty phase, at least one emulsifying surfactant with an HLB less than or equal to 8, at least one lipophilic filmforming polymer, at least one ester-terminated polyester polyamide, and at least one coloring material.

A photoluminescent nanocomposite material according to one aspect of the present invention includes a carrier matrix, a plurality of photoluminescence nanostructures distributed in the carrier matrix, and an additive including one or more coordination complexes having thiol and lipophilic properties.

The application discloses a preparation method of soybean oil body with antioxidant effect, and relates to the field of food processing and storage. The inner core of natural soybean oil body is hydrophobic triglyceride, which is lipophilic, and the outer part is covered by a phospholipid-oil body protein film, which is hydrophilic. The application utilizes the structural characteristics of natural soybean oil body with amphiphilicity, couples small-molecule compounds with antioxidant effect with soybean oil body protein, and wraps the antioxidant active substances into the inner part of the soybean oil body to prepare soybean oil body composite particles with antioxidant effect. The application improves the antioxidant capacity and storage stability of the soybean oil body.

The present invention relates to a solid composition comprising a lipophilic drug (such as a cannabinoid or Vitamin E) and a cyclodextrin wherein the lipophilic drug and the cyclodextrin are in the form of a combined complexation, and the lipophilic drug and the cyclodextrin in the combined complexation are either at a molar ratio of about 1:2; and methods of obtaining the same.

LIQUID COSMETIC COMPOSITION COMPRISING SILICONE OILS AND HYDROCARBON-BASED OILS, AND THEIR PROCESSES This disclosure relates to a liquid cosmetic composition for skin and lip makeup, comprising a non-volatile, non-polar hydrocarbon-based oil, a volatile, non-polar hydrocarbon-based oil, a mixture of at least one volatile silicone oil and at least one non-volatile silicone oil, a trimethylsiloxysilicate, and a lipophilic gelling agent. Figure for abstract: none

The invention discloses a core-shell microcapsule and a preparation method thereof, and relates to the technical field of daily chemical products. The core-shell microcapsule comprises a microcapsule core with a hydrophobic material and a microcapsule shell for encapsulating the microcapsule core, the microcapsule shell comprises hybrid thermosetting resin formed by reacting multifunctional amine with epoxy resin and acrylate respectively, a coordination polymer formed by an anionic polymer containing carboxylate radicals and divalent cations, and a polyion compound formed by the anionic polymer containing carboxylate radicals and a cationic polymer. The core-shell microcapsule disclosed by the invention is suitable for wrapping various hydrophobic / lipophilic oily core materials, shows good stability in a high-temperature washing liquid environment and good adhesion performance on fabrics, and the capsule shell material has a biodegradable characteristic, so that the coating of essence can be effectively realized and the functional requirement of generating fragrance by friction can be met; the environment friendliness, the use safety and the application functionality are realized.

The application provides a palladium ion extractant material and a preparation method thereof, and the pyridine-oxadiazole ligand is used as the extractant, most Pd 2+ in the aqueous phase can be extracted into the organic phase in a short time, and has a very high extraction rate; selective extraction separation of Pd 2+ under acidic conditions can be realized, the applicable range of acidity is wide, and excellent extraction capacity is achieved in the range of 0.2-4M nitric acid concentration; the extractant has excellent selectivity to Pd 2+ in the aqueous phase containing various metal ions; the pyridine-oxadiazole extractant has a good application prospect in the separation and recovery of Pd 2+ in high-level radioactive waste; the m-nitro-trifluorotoluene is used as a diluent of the extraction system, has good solubility to the organic ligand and the extractant, and the 2-bromohexanoic acid can increase the lipophilicity of the extractant.

The invention discloses a preparation method of tacrolimus capsules, and relates to the technical field of medicines. The preparation method comprises the following steps: S1, preparing a drug-loaded pellet core; s2, coating and curing a flexible buffer layer, namely curing for 8 hours under the conditions that the temperature is 100 DEG C and the relative humidity is 35%, so that the xanthan gum is in a swelling state; s3, coating with a high-barrier layer; s4, protective controlled release layer coating: preparing a coating solution from the third polymer grafted with the lipophilic bile salt derivative and phospholipid; and S5, capsule filling. Through functional gradient multilayer structure design and fine regulation and control of phospholipid composition and spatial distribution, multiple technical problems of poor chemical stability of tacrolimus, brittle rupture of a coating, burst drug release, dissolution and absorption disorder and release drift caused by individual difference of gastric emptying are synergistically solved; the excellent mechanical strength, stable and controllable release kinetics and obvious solubilization promoting effect of the pellet are realized. The method is clear in technological parameters and suitable for industrial production.

Keratinous Material Makeup Composition. The present invention relates to a composition, preferably a keratinous material makeup composition, comprising: (a) at least 5% by weight of at least one MQ resin, relative to the total weight of the composition; (b) at least one organic lipophilic gelling agent; and (c) at least 25% by weight of at least one aqueous solvent, relative to the total weight of the composition. Figure for the abstract: none

The present invention relates to an anhydrous composition for caring for and / or making up keratin materials, in particular the eyebrows and the eyes and the skin around the eyebrows, comprising, in particular in a physiologically acceptable medium: (a) at least one non-glycerolated silicone resin; and (b) at least one glycerated silicone resin; and (c) at least one silicone adhesive; and (d) at least one oil phase comprising at least one volatile hydrocarbon oil; and (e) a lipophilic thickener. The invention also relates to a method for coating keratin materials, in particular the eyebrows and the eye and the skin around the eyebrows, and more particularly to a method for making up said keratin materials, comprising the application to them of a composition as defined above.

The application discloses a ginseng stem and leaf composition based on fine extraction, a tablet and a production process, belongs to the technical field of natural medicine preparation, and aims to solve the problems of low utilization rate of ginseng stem and leaf components, complex rare saponin conversion process and poor bioavailability of products in the prior art. The core process comprises the following steps: fine separation of hydrophilic ginseng flavone / ginseng polysaccharide component A and saponin precursor component by adopting enzyme-assisted extraction combined with double-membrane filtration and fractional elution; solid phase thermal conversion of the saponin precursor component into lipophilic conversion component B rich in rare saponins Rg5, Rk1 and Rh4 by using a solid acid catalyst; and further preparation of the lipophilic conversion component B into a solid self-microemulsifying carrier, and compression of the hydrophilic ginseng flavone / ginseng polysaccharide component into a double-layer tablet.

To provide a stable composition that, despite containing a large amount of water, can not only provide a refreshing sensation but also reduce or eliminate a sticky feeling. [Solution] The present invention relates to a composition comprising (a1) at least one first polyglyceryl fatty acid ester having an HLB value of 4 or less, (a2) at least one second polyglyceryl fatty acid ester having an HLB value greater than 4, (b) at least one lipophilic thickener, (c) at least one hydrophilic thickener selected from nonionic polysaccharides, (d) at least one oil, and (e) water, wherein (e) the amount of water is more than 50% by mass of the total mass of the composition, and the composition does not contain silicone, or contains less than 1% by mass, preferably less than 0.5% by mass, more preferably less than 0.1% by mass of silicone, based on the total mass of the composition. Despite containing a large amount of water, the composition according to the present invention is stable and can provide a refreshing sensation, such as a water-repellent feeling, as well as reducing or eliminating a sticky feeling.

A composition for conditioning keratin fibres comprising: a) at least one spherical particle of lipophilic modified silica; b) at least one superabsorbent polymer selected from starches grafted with acrylic polymers; and c) at least one hyaluronic acid cross-linked polymer. A cosmetic process for conditioning keratin fibers comprising applying a composition to the keratin fibers.

An ozone-containing composition comprises a volatile oily solvent, a volatile aqueous solvent, and ozone. The volatile oily solvent is present in a concentration ranging from 1 wt % to 99 wt % based on the total composition. The volatile aqueous solvent is present in a concentration ranging from 1 wt % to 99 wt % based on the total composition. The volatile oily solvent is a volatile liquid paraffin having a boiling point of 170 degrees and being lipophilic, a volatile silicone oil having a boiling point ranging from 170 degrees to 200 degrees and being lipophilic, or a mixture of the volatile liquid paraffin and the volatile silicone oil. The volatile liquid paraffin is one or more volatile liquid paraffins selected from the group consisting of light isoparaffin, light liquid isoparaffin, and hydrogenated polyisobutene. The volatile silicone oil is a volatile silicone oil containing cyclic dimethyl silicone oil. The volatile aqueous solvent is a volatile alcohol having a boiling point of 150 degrees or less and being hydrophilic and lipophilic, a volatile ketone having a boiling point of 150 degrees or less and being hydrophilic and lipophilic, or a mixture of the volatile alcohol and the volatile ketone. The volatile alcohol comprises ethanol, isopropyl alcohol, or 1-pentanol. The volatile ketone comprises methyl ethyl ketone, or 2-hexanone. The ozone-containing composition is for use in killing insects, repelling pests, or decontaminating and decomposing anticancer drugs.

The present application relates to the field of agricultural organic chemistry, and provides an abamectin B 2a Carbamate derivatives, preparation method and application thereof, by introducing nitrogen-containing lipophilic functional groups at C4" position of abamectin B 2a Carbamate derivatives, by modifying and modifying the structure of abamectin B 2a Carbamate derivatives, by modifying and modifying the structure of abamectin B 2a Carbamate derivatives, by modifying and modifying the structure of abamectin B 2a Carbamate derivatives, by modifying and modifying the structure of abamectin B 2a Carbamate derivatives can be used for preventing and treating harmful organisms that harm ornamental plants and crops, especially organisms that harm fruits, flowers, leaves, stems, tubers or roots of plants, and also can be used for protecting growing plants from the invasion of harmful organisms.

Implants containing lipophilic pharmaceutical agents are described. Excipients are used that provide adequate and controllable / tunable release of the lipophilic drug from the matrix of the implant. The implants can be implanted in a patient for release of the pharmaceutical agent. Methods for making and using such implants are also described.