The invention provides a method for preparing a
chitosan-based silver-loaded composite
antimicrobial superfine
fiber membrane. The method is characterized by particularly comprising the following steps: 1, adding
silver nitrate powder into an
acetic acid aqueous solution with the
mass fraction of 50-90%, stirring to dissolve to obtain a solution, weighing and adding
chitosan and polyoxyethylene or
polyvinyl alcohol powder into the solution, and stirring to obtain a
spinning solution; and 2, adding the
spinning solution into an electrostatic
spinning device, carrying out electrostatic spinning under the conditions that the
voltage is 10-20kv, the spinning solution injecting speed is 0.1-1.0mL / h, the receive distance is 8-30cm, the spinning temperature is 20-50 DEG C and the
relative humidity is 10-55%, carrying out
vacuum drying on the obtained white
nanofiber membrane for 12-36 hours, and removing the
residual solvent to obtain the
chitosan-based silver-loaded composite
antimicrobial superfine
fiber membrane. The
electrospun fiber membrane has the advantages of a certain
mechanical property, good
antimicrobial property and water absorbing ability and can be used for the fields of
wound surface nursing and medical dressings with different anti-infection requirements through designing the
compositing ratio of the chitosan and the nanometer silver.