159 results about "Electrospun fiber" patented technology

The present invention relates to an electrospun fiber, a process for preparing the same, a nonwoven fabric comprising the electrospun fiber, as well as corresponding uses and articles. The inventive electrospun fiber comprises a polymer, a surface-reacted calcium carbonate and a pharmaceutically or nutraceutically active ingredient, wherein at least a part of the pharmaceutically or nutraceutically active ingredient is present within the pores of the surface-reacted calcium carbonate. The inventive fibers may be used e.g. in yarns, transdermal patches, intrabuccal patches, implantable textiles, wound dressings and / or medical tapes.

Aspects of the disclosure relate to synthetic tissue or organ scaffolds and methods and compositions for promoting or maintaining their structural integrity. Aspects of the disclosure are useful to prevent scaffold damage (e.g., delamination) during or after implantation into a host. Aspects of the disclosure are useful to stabilize tissue or organ scaffolds that include electrospun fibers.

The invention relates to the field of textile fabrics, and particularly discloses an antibacterial and crease-resistant garment fabric and a preparation process thereof. The antibacterial and crease-resistant garment fabric is prepared from modified cotton fibers and electrospun fibers of polyacrylonitrile and polyurethane according to the mass ratio of 1: (0.1-0.3): (0.3-0.5), and a preparation method of the polylactic acid fiber modified cotton fibers containing silver nanowires comprises the following steps that the cotton fibers are padded in finishing liquid and then dried and shaped, and pretreated cotton fibers are prepared; the pretreated cotton fibers are padded in the treating fluid and then dried and baked, and modified cotton fibers are prepared; the finishing liquid is prepared from the following raw materials: citric acid modified titanium dioxide sol, sodium hypophosphite, triethanolamine and deionized water; the treating fluid is prepared from the following raw materials: nylon waste silk, chitosan quaternary ammonium salt, N, N-dimethylformamide and alkaline silica sol. The garment fabric has the advantages of being good in antibacterial and crease-resistant effect, lasting in antibacterial effect and high in breaking strength.

The invention discloses a bimetal MOFs-loaded electrostatic spinning fiber membrane for oil-water separation and a preparation method thereof, and belongs to the technical field of membrane separation, and the preparation method comprises the following steps: (1) preparing a hydroxyl-modified metal organic framework material MIL-53 (Al)-OH through a solvothermal reaction; (2) preparing an MIL-53 (Fe) precursor solution by using ferric salt, terephthalic acid, polyvinylpyrrolidone and an organic solvent, ultrasonically dispersing MIL-53 (Al)-OH in the MIL-53 (Fe) precursor solution, uniformly mixing, and soaking the electrostatic spinning fiber membrane in the MIL-53 (Fe) precursor solution for 1-3 hours; and (3) transferring the system in the step (2) into a reaction kettle, reacting at 130-150 DEG C for 10-15 hours to enable the bimetallic MOFs to grow on the surface of the electrostatic spinning fiber membrane, washing, and drying to obtain the bimetallic MOFs-loaded electrostatic spinning fiber membrane for oil-water separation. The bimetal MOFs-loaded electrostatic spinning fiber membrane has the advantages of good oil-water separation performance, strong antifouling ability and strong dye degradation ability.

Disclosed herein are non-woven graft materials for use in specialized surgical procedures involving nerve repair and regeneration. Some embodiments describe electrospun fiber products such as conduits, wraps, or grafts comprising a resorbable hybrid-scale matrix to facilitate nerve repair and regeneration.

The invention relates to the technical field of medical instruments, in particular to a multi-layer ultra-light hernia patch which comprises a large-mesh electrostatic spinning tissue ingrowth layer, a mesh woven base material layer and an anti-adhesion layer which are sequentially connected in a stacked mode. Wherein after the large-mesh electrostatic spinning tissue ingrowth layer is implanted into a human body, a cell microenvironment can be better simulated, cell adhesion, differentiation and migration are facilitated, uniform distribution of newborn cells in the fiber direction of an electrospinning membrane is promoted, granulation tissues uniformly ingrow in a defect part, and the electrospinning fiber membrane and the tissues are cooperatively repaired; secondly, the middle layer can provide supporting performance and mechanical performance of the patch in the early stage for the patch, the defects of the electrospinning fiber membrane in the supporting performance and the mechanical performance are overcome, the long-term implantation amount of the patch after later degradation is greatly reduced, and the foreign body sensation is obviously reduced; the anti-adhesion layer also adopts the electrostatic spinning technology, and the anti-adhesion effect is achieved by selecting materials and regulating and controlling the porosity, the aperture and the fiber diameter of the electrospun fiber membrane.

A dry drug delivery system comprising a middle layer encased in two outer layers, the middle layer and the two outer layers each comprising a mixture of electrospun fibers. Also disclosed is a water-dissolvable dry device containing a physical mixture of a first fiber and a second fiber in which the first fiber and the second fiber are configured to react with each other and with a biological tissue upon hydration, and the device transforms into a hydrogel upon contact with the biological tissue. Further provided is a method for delivering a bioactive substance to a soft tissue using the system or device.

The invention relates to a nerve-promoting electrostatic spinning fiber membrane, the nerve-promoting electrostatic spinning fiber membrane comprises a plurality of nanofibers loaded with 3, 5-DHBA / Zn-MOF particles, the 3, 5-DHBA / Zn-MOF particles are formed by self-assembly of Zn < 2 + > and 3, 5-DHBA, and the mass percentage of Zn < 2 + > in the nerve-promoting electrostatic spinning fiber membrane is 0.48-0.66%. The nanofiber membrane containing 3, 5-DHBA / Zn-MOF particles prepared by the invention not only can remove ROS (reactive oxygen species), but also can be used as a functional electrospun membrane for promoting vascular nerves to jointly and mutually repair diabetic wounds, the preparation method is simple and easy to implement, and the raw materials are affordable and easy to obtain.

The invention discloses a solid electrolyte using an electrostatic spinning fiber membrane as a matrix and a preparation method and application thereof, and the preparation method of the solid electrolyte specifically comprises the following steps: (1) sequentially dissolving PVDF powder and commercial tetragonal phase BaTiO3 (BTO) powder in a mixed solvent of DMF and THF, and uniformly stirring with a magnetic stirrer to obtain a PVDF / BTO solution; and (2) carrying out electrostatic spinning on the PVDF / BTO solution to prepare a fiber membrane, drying, and carrying out a solution pouring method to prepare the composite solid electrolyte film. Compared with the prior art, the prepared solid electrolyte has excellent cycle performance, the ion transference number of the solid electrolyte is greatly increased, and the solid electrolyte has good lithium metal negative electrode compatibility.

The invention belongs to the technical field of flexible electronic materials and sensing, and particularly relates to a PVDF (polyvinylidene fluoride) fiber membrane doped with a surface modified boron nitride nano material and a preparation method of the PVDF fiber membrane. The PVDF fiber membrane is prepared by adopting an electrostatic spinning method, and a surface-modified boron nitride (BN) nano material is doped during spinning, so that the electrospun PVDF / BN composite fiber membrane is prepared. The piezoelectric property of the electrospun PVDF fiber membrane can be effectively improved by adding the boron nitride, the dispersity of the boron nitride nano material in PVDF can be improved after the boron nitride nano material is subjected to surface modification, and the piezoelectric property of the composite fiber membrane is further enhanced. The electrospinning PVDF / BN flexible piezoelectric fiber membrane provided by the invention can be widely applied to the fields of human health monitoring, intelligent wearable equipment, biomedical treatment and the like.

The invention discloses a multifunctional composite flexible fabric which has multiple functions of radiation refrigeration, energy collection, hydrophobicity and antibiosis. The composite flexible fabric is composed of a plurality of electrostatic spinning fiber layers, and all the layers are formed through electrostatic spinning in sequence from top to bottom. Comprising at least two polymer electrospinning fiber layers and at least one nanometer functional electrospinning fiber layer, the nanometer functional electrospinning fiber layer is a middle interlayer, and the nanometer functional electrospinning fiber layer and the polymer electrospinning fiber layers located on the upper surface and the lower surface respectively form a sandwich structure. The invention also discloses a preparation method of the flexible fabric, and the flexible fabric is prepared by electrostatic spinning of PVDF or a series of polymer solutions thereof and a polymer solution modified by adding functional nanoparticles by using an electrostatic spinning method. The preparation method can effectively regulate and control the form of the nanofiber and the functions of the nanoparticles, so that the functional scattering nanoparticles and the nanofiber generate a synergistic effect, and the functional fabric with thermal management, energy collection and antibacterial properties is integrated.

The invention provides a pH response type self-repairing electrostatic spinning fiber material and a synthesis method and application thereof.According to the method, pH response type micro / nano containers are evenly distributed in a polymer matrix through the electrostatic spinning technology, so that the self-repairing function of a coating is achieved, and the method is particularly suitable for the field of anticorrosive coatings.

The invention discloses a photodynamic antibacterial fiber membrane and a preparation method and application thereof, and relates to the field of functional materials.The preparation method comprises the steps that aggregation-induced emission photosensitive molecules are dissolved in a first solvent, and a photosensitive molecule solution is obtained; dissolving the purified polymer in a second solvent, and adding a photosensitive molecular solution to obtain a spinning precursor solution; adjusting and controlling the orientation degree of the spinning precursor solution through electrostatic spinning to obtain a fiber membrane; adjusting and controlling the crystallinity of the fiber membrane to obtain the photodynamic antibacterial fiber membrane. According to the preparation method provided by the invention, a polymer condensed state structure is combined with aggregation-induced emission photosensitive molecules, and a rigid confinement domain is provided for the photosensitive molecules by utilizing polymer crystallization and an orientation structure; meanwhile, the contact area between the material and oxygen is increased by utilizing the nanoscale of the electrostatic spinning fiber membrane, and the active oxygen yield of the material is synergistically improved.

The invention relates to a eugenol liposome / chitosan / polyoxyethylene hydrophobic electrospun fibrous membrane and a preparation method thereof, and the method comprises the following steps: based on soybean lecithin and cholesterol, adding eugenol and Tween 80, preparing a lipid solution, injecting the lipid solution into water or a phosphate buffer solution, and preparing an eugenol liposome suspension with the eugenol embedding rate greater than 88%; preparing a cross-linked chitosan acetic acid solution based on chitosan and a cross-linking agent; preparing a polyoxyethylene acetic acid solution, and mixing the cross-linked chitosan acetic acid solution with the polyoxyethylene acetic acid solution to obtain a base material spinning solution; mixing the eugenol liposome suspension with a base material spinning solution to prepare a final spinning solution, and preparing the eugenol liposome / chitosan / polyoxyethylene hydrophobic electrospinning fiber membrane by adopting an electrostatic spinning method. The embedding rate of eugenol is high, the water contact angle of the fiber membrane can reach 90 degrees or above, the slow release effect on eugenol is good, and the antibacterial and fresh-keeping effects are improved.

This invention discloses a multifunctional composite flexible fabric with multiple functions including radiative cooling, energy harvesting, hydrophobicity, and antibacterial properties. The composite flexible fabric consists of several electrospun fiber layers, each formed sequentially by electrospinning in a top-to-bottom order. It includes at least two polymer electrospun fiber layers and at least one nanofunctional electrospun fiber layer, wherein the nanofunctional electrospun fiber layer serves as an intermediate sandwich layer, forming a sandwich structure with the polymer electrospun fiber layers located on the upper and lower surfaces. This invention also discloses a method for preparing this flexible fabric, using electrospinning to prepare it by electrospinning a PVDF or related polymer solution and a polymer solution modified with functional nanoparticles. This preparation method can effectively control the morphology of the nanofibers and the functions of the nanoparticles, enabling a synergistic effect between the functional nano-scattering particles and the nanofibers, resulting in an integrated functional fabric with thermal management, energy harvesting, and antibacterial properties.

The invention provides a genetically engineered oriented electrostatic spinning fiber as well as a preparation method and application thereof, and belongs to the technical field of biomedical materials. Gene TSPAN9 is packaged in liposome through a micro-fluidic chip technology, then oriented electrostatic spinning fibers of a shell-core structure are prepared through an oriented micro-sol electrostatic spinning technology, and the liposome containing the TSPAN9 is protected on a core layer by hyaluronic acid; and the polylactic acid fibers are arranged in an oriented manner to form a shell layer. An in-vitro experiment shows that the oriented fiber closely simulates a fascia oriented arrangement structure, and the cell migration rate is remarkably improved through contact guidance; by slowly releasing lipidosome loaded with genes into cells and maintaining the mitochondrial steady state, mitochondrial respiration is effectively recovered, the active oxygen level is reduced, and the mitochondrial membrane potential function is maintained. In-vivo experiments show that the genetically engineered fiber can effectively inhibit inflammatory response and promote fascia tissue regeneration by promoting mitochondrial exocytosis to discharge damaged mitochondria.

The invention discloses a multifunctional wound patch combined with electrical stimulation therapy and a preparation method and application thereof, and relates to the technical field of medical materials, and the multifunctional wound patch comprises a double-layer electrostatic spinning fiber membrane, a conductive ink layer and a conductive hydrogel layer. S-shaped concentric circle conductive electrode pairs written by conductive ink are integrated on the surface (directly in contact with the wound) of the hydrophobic fiber layer, and square conductive ports with corresponding sizes can be drawn at the tail ends of the two electrodes as required. And the surface of the conductive electrode pair is packaged by conductive hydrogel with an antibacterial function. An external electric signal can be transmitted to the electrode pair of the patch through the conductive port of the electrode pair, and then acts on a wound through the conductive hydrogel layer, so that on-demand electrical stimulation treatment on the wound is realized. According to the multifunctional wound patch combined with the electrical stimulation therapy, discharge of redundant seepage can be achieved, and it is guaranteed that the wound environment is good; the curcumin-loaded medicine has the effects of resisting bacteria, resisting oxidation and promoting healing on wounds.

A method for controlling fiber cross-alignment in a nanofiber membrane, comprising: providing a multiple segment collector in an electrospinning device including a first and second segment electrically isolated from an intermediate segment positioned between the first and second segment, collectively presenting a cylindrical structure, rotating the cylindrical structure around a longitudinal axis proximate to an electrically charged fiber emitter; electrically grounding or charging edge conductors circumferentially resident on the first and second segment, maintaining intermediate collector electrically neutral; dispensing electrospun fiber toward the collector, the fiber attaching to edge conductors and spanning the separation space between edge conductors; attracting electrospun fiber attached to the edge conductors to the surface of the cylindrical structure, forming a first fiber layer; increasing or decreasing rotation speed of the cylindrical structure to alter the angular cross-alignment relationship between aligned nanofibers in adjacent layers, the rotation speed being altered to achieve a target relational angle.

The disclosed concept includes systems and methods for the delivery of magnesium to a patient to modulate the human immune system and create an anti-inflammatory periodontal environment to support tissue regeneration. Various mechanisms for the delivery of magnesium include magnesium-polymer (PLGA) microparticles, magnesium-polymer (PLGA) electrospun fibers, and / or magnesium-polymer (PLGA) implant devices, e.g., scaffolds, constructed of the magnesium-polymer (PLGA) electrospun fibers. These mechanisms provide a controlled- and / or sustained-release of magnesium for the treatment of one or more of periodontitis, peri-implantitis, and bone defects. The magnesium-polymer (PLGA) microparticles include magnesium metal nanopowder that is coated with a fatty acid or lipid.

The invention relates to preparation of a multi-layer composite flame-retardant fiber material combining far infrared rays and negative ions. The preparation method comprises the following steps: modification of tourmaline powder, preparation of a flame retardant from modified GO, preparation of polyester slurry, preparation of an electrostatic spinning solution, preparation of tourmaline fibers, preparation of flame-retardant composite fibers, preparation of electrostatic spinning PPSU / PU fiber sponge and preparation of a multi-layer composite flame-retardant fiber material. A gel method and an electrostatic spinning method are creatively combined, the prepared material is beneficial to improving comfort, the flame retardant property of the fiber material is improved, and the fiber material has the advantages of being high in antibacterial property, good in flame retardant property and the like.

The application belongs to the field of functional material preparation, and particularly relates to a preparation method of a super-light high-nucleic-acid-absorption electrospun fiber sponge material and application thereof. The SiO2 electrospun fiber is used as a framework, a three-dimensional monolithic structure assembled by fragmented electrospun nanofiber membranes is used, the interconnected nanofiber cell structures of which endow the three-dimensional monolithic structure with high porosity and excellent structural flexibility and stability. Meanwhile, the amino-rich polyethylene imine and chitosan are chemically crosslinked by using epichlorohydrin as a crosslinking agent, and finally during freeze-drying, the ice crystals are partially sublimated, leaving a pore structure, and a porous sponge material is obtained. The material has a high nucleic acid adsorption capacity, and makes nucleic acid extraction more simple, rapid and sensitive.

A flexible barrier laminate comprising a cellulose fiber-based substrate layer (1), a barrier layer (2) comprising an electrospun fiber web, deposited on one side of the substrate layer.

The invention relates to the technical field of composite membranes, in particular to a PLLA / DFSCs composite membrane and a preparation method thereof.DFSCs are cultured after being separated, then the DFSCs are inoculated to a PLLA electrostatic spinning fiber membrane to be cultured, and the final PLLA / DFSCs composite cell membrane is obtained. The method comprises the following steps: inoculating DFSCs to a PLLA bracket, and carrying out flat culture for 3 days to construct a P-CS composite cell sheet; compared with a traditional membrane (the culture period is 14-28 days), the P-CS composite membrane only needs to be cultured for 3 days, so that the culture time of the cell membrane is greatly shortened; compared with a traditional diaphragm (CS), the P-CS composite diaphragm has excellent mechanical strength and plasticity and is suitable for different defect surface plasticity.

This application discloses a photodynamic antibacterial fiber membrane and its preparation method and application, which relates to the field of functional materials, including: dissolving aggregation-induced luminescence photosensitive molecules in a first solvent to obtain a photosensitive molecule solution; dissolving the purified polymer in a second solvent and adding the photosensitive molecule solution to obtain a spinning precursor; regulating the orientation of the spinning precursor by electrospinning to obtain a fiber membrane; and regulating the crystallinity of the fiber membrane to obtain a photodynamic antibacterial fiber membrane. The preparation method provided in this application combines the polymer condensed state structure with aggregation-induced luminescence photosensitive molecules, using the polymer crystallization and orientation structure to provide a rigid confined domain for the photosensitive molecules; at the same time, the nanoscale of the electrospun fiber membrane is used to increase the contact area between the material and oxygen, synergistically improving the material's active oxygen yield.

The invention relates to the technical field of material engineering, in particular to a lignocellulose-based amphiphilic polymer, an electrospun fiber film and a preparation method thereof. The preparation method comprises the following steps: pre-treating agricultural product processing byproducts by adopting a chemical method and / or a biological method to obtain lignocellulose; the method comprises the following steps: taking lignocellulose as a raw material, carrying out high-pressure homogenization treatment to obtain lignocellulose nanofibers, mixing the lignocellulose nanofibers, an aliphatic monomer and a catalyst, and carrying out high-temperature polymerization to obtain the lignocellulose-based amphiphilic polymer. The invention further provides a porous electrospun fiber film which is converted from a mixture of the lignocellulose-based amphiphilic polymer and the aliphatic polymer and has excellent mechanical strength, flexibility and biocompatibility, and the porous electrospun fiber film can be widely applied to the biomedical fields of wound dressing, tissue engineering and the like. And optimal regulation and control of material performance and efficient utilization of agricultural product processing byproducts are realized.

The application provides a preparation method of a down-like heat storage and preservation material, and comprises the following steps: dissolving polylactic acid in a mixed solution of chloroform / acetone to obtain a polylactic acid solution; dissolving composite hollow spheres in a mixed solution of chloroform / acetone to obtain a composite hollow sphere solution; using the polylactic acid solution as a shell layer solution and the composite hollow sphere solution as a core layer solution, adopting a coaxial conjugate electrospinning instrument to prepare a fiber bundle, the spinning voltage is 12-14 kV, the distance between composite spinnerets is 25-30 cm, the flow rate of the shell layer solution is 0.5-3 mL / h, and the flow rate of the core layer solution is 0.5-3 mL / h, to obtain an electrospun fiber bundle; using the electrospun fiber bundle as a covering yarn and polylactic acid filaments as core yarns, the down-like heat storage and preservation material is obtained by covering. The application adopts the electrospinning method to prepare the fiber bundle, and adds the composite hollow spheres in the core layer of the fiber bundle, uses the electrospun fiber bundle as the covering layer and the ordinary filaments as the core layer, so that a heat storage and preservation effect of the down-like heat storage and preservation material is better than that of ordinary air long down material.

A barrier laminate comprising a substrate layer (1), a connection layer (2) comprising an electrospun fiber network, and a non-fiber-based sealing layer (3), adjacent to the connection layer (2) and facing the outside of the laminate.

A porous membrane can include a first plurality of near-field electrospun fibers that are substantially parallel one to another. A second plurality of near-field electrospun fibers can be deposited over the first plurality of fibers. The second plurality of fibers can also be substantially parallel one to another. The second plurality of fibers can be transverse to the first plurality of fibers, such that the second plurality of fibers cross the first plurality of fibers to form pores between adjacent fibers of the first plurality of fibers and adjacent fibers of the second plurality of fibers.

This invention provides a medical repair membrane with an orthogonal crack-limiting structure and its preparation method. This invention relates to the field of biomedical materials technology. The medical repair membrane of this invention comprises at least two electrospun fiber layers, which intersect to form an orthogonal fiber structure. Layer B, facing tissue integration, adopts a coaxial core-shell structure. The shell layer contains biodegradable polymers and bioactive components, while the core layer is a biodegradable polymer. The structure of this invention effectively inhibits crack propagation and improves the structural stability of the material. Simultaneously, the core-shell structure enables controlled release of active components and tissue-selective induction, balancing mechanical properties and biocompatibility. The medical repair membrane is suitable for soft tissue defect repair, such as dura mater repair, fascia repair, pericardial repair, and hernia repair.

The present invention provides a composite dressing with continuous unidirectional moisture conduction capability and a preparation method thereof, wherein a hydrophobic silk fiber membrane and a hydrophilic electrospun cellulose membrane are respectively arranged on both sides of a super absorbent sponge to obtain a unidirectional moisture conduction dressing, and then a graphene oxide dispersion is evenly sprayed onto the surface of one side of the hydrophilic electrospun cellulose membrane to obtain the composite dressing. The present invention realizes unidirectional continuous transport of exudate through a hierarchical multi-level pore structure jointly constructed by a hydrophobic layer, a hydrophilic sponge and a hydrophilic layer containing graphene oxide.