12 results about "Electrospun fiber" patented technology

This invention provides a medical repair membrane with an orthogonal crack-limiting structure and its preparation method. This invention relates to the field of biomedical materials technology. The medical repair membrane of this invention comprises at least two electrospun fiber layers, which intersect to form an orthogonal fiber structure. Layer B, facing tissue integration, adopts a coaxial core-shell structure. The shell layer contains biodegradable polymers and bioactive components, while the core layer is a biodegradable polymer. The structure of this invention effectively inhibits crack propagation and improves the structural stability of the material. Simultaneously, the core-shell structure enables controlled release of active components and tissue-selective induction, balancing mechanical properties and biocompatibility. The medical repair membrane is suitable for soft tissue defect repair, such as dura mater repair, fascia repair, pericardial repair, and hernia repair.

The present disclosure provides a PI-in-situ functionalized bimetallic MOF / phosphoric acid proton exchange membrane and a preparation method and an aqueous organic flow battery. The preparation method comprises: sequentially adding diamine monomers and dianhydride monomers in a polar solvent and stirring to form a viscous polyamide acid spinning solution; electrospinning the spinning solution to obtain a PAA fiber membrane; gradient temperature imidization of the PAA fiber membrane to obtain a PI electrospun fiber membrane; plasma pretreatment of the PI electrospun fiber membrane to obtain a surface-activated PI electrospun fiber membrane; placing a sulfonated modified bimetallic MOF reaction solution and the PI electrospun fiber membrane in a reaction kettle by a solvothermal in-situ growth method to obtain a PI@ sulfonated modified bimetallic MOF composite fiber membrane; soaking the PI@ sulfonated modified bimetallic MOF composite fiber membrane in a phosphoric acid solution containing a silane coupling agent for soaking treatment, and then performing heat pressing densification and drying treatment to obtain a PI-in-situ functionalized bimetallic MOF / phosphoric acid composite proton exchange membrane.

The application provides a preparation method of an anti-ultraviolet / super-hydrophobic multifunctional silk cashmere fabric, comprising the following steps: S1, adding polylactic acid powder into dichloromethane to obtain a polylactic acid solution; S2, covering the silk cashmere fabric on a receiving plate, smearing a layer of silk fibroin protein solution on the surface of the silk cashmere fabric, and preparing an electrospun fiber layer on one side of the surface of the silk cashmere fabric on which the silk fibroin protein solution is smeared through electrospinning; S3, adding raspberry-shaped CeO2 / SiO2 composite microspheres into an N, N-dimethylformamide solution, ultrasonic dispersion, then adding polylactic acid and dichloromethane into the above solution, stirring and dissolving to obtain a composite microsphere / polylactic acid precursor solution; and S4, taking the electrospun fiber layer prepared in step S2 as a receiving surface, and performing electrostatic spraying to obtain the anti-ultraviolet / super-hydrophobic multifunctional silk cashmere fabric. Through cooperation of the electrospinning and electrostatic spraying methods, the dispersibility and the bonding strength of nanometer cerium dioxide are improved.

The present application relates to a kind of multifunctional medical fiber membrane and its preparation method and application, the multifunctional medical fiber membrane is with including poly high molecular material, material with anionic group, collagen and ε-polylysine in it Material is raw material, using the electrospun fiber membrane prepared by conjugated electrospinning technology.This medical fiber membrane has the advantages of electrospun membrane and self-assembly membrane simultaneously, close to the structure of extracellular matrix, can provide a large number of cell contact points, provide better microenvironment for cell adhesion, proliferation, physiological function;It contains collagen and ε-polylysine in composition, can make it have good hydrophilicity and antibacterial property, the addition of material with anionic group makes collagen and ε-polylysine more stably combined on fiber membrane, so that it slowly releases, while its own good characteristics make product can be directly attached in clinical use, more effectively induce cell growth and tissue regeneration, and then effectively promote the repair of wound surface.

An article comprising a multilayer matrix is provided, the matrix comprising a viscoelastic polymer film sandwiched between two or more layers of an elastic polymeric material; wherein each of the two or more layers of the elastic polymeric material is in the form of a fibrous mat; the fibrous mat (i) comprising a plurality of electrospun fibers characterized by an average cross-sectional dimension of between about 1 and about 5 microns, and (ii) characterized by an average pore size of between about 5 and about 50 microns; the viscoelastic polymer film characterized by a thickness of between about 10 and about 60 um; the viscoelastic polymer film characterized by a melting peak temperature of between 30 and about 45 °C; and the two or more layers of the elastic polymeric material comprising PLCL characterized by a Mw of between 78 and about 100 kDa. Methods of making the article are also provided.

The application provides an asymmetric anti-adhesion composite film and a preparation method and application thereof. The composite film comprises a bioactive layer and an electrospun fiber layer, and the electrospun fiber layer comprises a first fiber layer and a second fiber layer. The first fiber layer comprises fibers with a first diameter. The second fiber layer comprises fibers with the first diameter and fibers with a second diameter, and the first diameter is larger than the second diameter. The composite film has strong mechanical and degradation resistance properties, and is suitable for anti-adhesion applications of various moving organoids or tissues, so that the composite film still has structural integrity and functional integrity for a long time in these environments. One side of the composite film has adhesive fibers, and has stronger adhesion in a wet state, so that the composite film cannot be easily displaced when applied to moving organoids or tissues.

This invention belongs to the field of biomaterials technology, specifically relating to a bioactive scaffold, its preparation method, and its applications. This invention incorporates functionalized mesoporous silica nanoparticles loaded with aminoguanidine into the skin secretions of the giant salamander and polycaprolactone electrospun fibers to construct a bioactive composite scaffold (SPMA). This scaffold enables the sustained release of AG and osteogenic factors, effectively inhibiting free radical generation, AGEs toxicity, and inflammatory responses. Furthermore, it significantly improves the survival rate, osteogenic differentiation, and mineralization capacity of bone marrow mesenchymal stem cells in a high-glucose microenvironment. In vivo experiments further demonstrate that in a streptozotocin-induced diabetic mouse model of skull defects, the SPMA scaffold can alleviate local inflammation, promote angiogenesis, and significantly accelerate new bone formation and defect repair.

This application discloses a fiber scaffold and its preparation method, a fiber scaffold system and its preparation method, belonging to the field of medical devices. The scaffold has a hollow tubular structure, including an inner fiber layer, a fiber support structure, and an outer fiber layer. The fiber support structure is coaxially sleeved on the outer surface of the inner fiber layer, and the outer fiber layer covers the outer surfaces of the inner fiber layer and the fiber support structure. The fiber porosity of the inner fiber layer is less than or equal to that of the outer fiber layer. The fiber support structure is composed of electrospun fibers and includes annular bodies distributed along the axial direction of the scaffold, with axial spacing between adjacent annular bodies to provide radial support. This application utilizes the annular bodies to provide radial support, while the axial spacing provides deformation space for bending, giving the scaffold both radial stiffness and axial flexibility; the differentiated porosity design is beneficial for cell infiltration and tissue regeneration, making it suitable for vascular interventional therapy.

This invention discloses a slow-release electrospun fiber sex pheromone for the Asian corn borer, its preparation method, and its application, relating to the field of pest control technology. The method employs coaxial electrospinning technology, using polyhydroxybutyrate (PHB) as the shell and polylactic acid-glycolic acid (PLA) copolymer as the core, loaded with Asian corn borer sex pheromones to prepare a core-shell structured nanofiber membrane. By optimizing the flow rate ratio of the shell and core layers, the resulting fiber membrane exhibits uniform fiber diameter, and the core-shell structure is clearly visible via TEM. FTIR and TGA analyses confirm successful loading of TDA into the fibers. The fiber membrane has a drug loading of 12.09%, an encapsulation efficiency of 78.56%, and an effective release time of up to 138 days, significantly superior to monoaxial fibers, achieving a 42% burst release inhibition rate in the initial release phase. Field trapping trials show that this fiber membrane is more effective at trapping Asian corn borers than monoaxial electrospun fibers and commercially available butyl rubber stopper carriers.

An electrochemical device component comprises at least one electro-spun fibre (1) comprising a core (2) and a sheath (3) surrounding the core. The core (2) comprises particles of an electrode active material (4) held together by a first polymeric material (6), and is electrically conductive along its length. The sheath (3) is formed from a second polymeric material, the second polymeric material being electrically insulating. The core (2) of the at least one electro-spun fibre (1) is arranged to provide a first electrode of an electrochemical device. The sheath (3) of the at least one electro- spun fibre (1) may be arranged to provide a separator between the first electrode and a counter electrode of the electrochemical device.

This invention provides a bismuth-containing composite fiber, its preparation method, and its applications. Specifically, this invention provides a bismuth-containing composite fiber, which is a polymer electrospun fiber with bismuth-bismuth oxide particles doped on its surface and / or internally. The polymer comprises a first polymer and a second polymer. The blending of the two polymers not only imparts excellent mechanical strength to the composite fiber but also ensures its biodegradability and biocompatibility. The introduction of bismuth-bismuth oxide particles endows the nanofiber with functional properties, enabling it to generate reactive oxygen species under ultrasound, achieving highly efficient antibacterial effects and thus meeting the customized functional requirements for antibacterial treatment on wound surfaces. The bismuth-containing composite fiber prepared by this invention has advantages such as good biocompatibility, excellent antibacterial effect, high mechanical strength, and low bioirritation, showing promising application prospects in biomedical fields such as wound dressings.

This invention discloses the preparation of a MOFs-based multifunctional three-dimensional network nanocomposite fiber membrane material and its application in the removal of radioactive iodine aerosols. The method includes: dissolving at least two polymers in an organic solvent, then adding MOFs powder and stirring to form a precursor solution; electrospinning the precursor solution to obtain the MOFs-based multifunctional three-dimensional network nanocomposite fiber membrane material. This invention provides new ideas for the design and synthesis of electrospun fiber membranes and for the deep purification of iodine aerosols. Furthermore, compared with other fiber membrane materials, this fiber membrane material exhibits good radiation stability, high adsorption capacity, and excellent filtration efficiency. It has potential applications in the field of nuclear fuel reprocessing technology, including the adsorption of radioactive iodine gas and methyl iodine, as well as the filtration of radioactive aerosols.