1290results about How to "Broad spectrum antibacterial" patented technology

The invention discloses a titanium alloy containing an antibacterial coating as well as a preparation method and application thereof. The titanium alloy deposited with nano-silver antibacterial coating on the surface is prepared by the following steps: preprocessing and sterilizing the surface of titanium alloy; then soaking the titanium alloy in a dopamine hydrochloride solution with mass-volume concentration of 1-10mg/mL for 12-36h to obtain titanium alloy deposited with a polydopamine thin film layer on the surface; and finally soaking the titanium alloy in a silver nitrate solution which is 5-100mmol/L in concentration for 12-36h. According to the titanium alloy disclosed by the invention, the titanium alloy is connected to silver nanoparticles by virtue of adhesion from self-polymerization of dopamine and adsorbed silver ions are reduced into nano-silver in situ through weak reducibility of the dopamine. Because of broad-spectrum antibacterial capacity of the nano-silver, an excellent antibacterial effect can be achieved with relatively low effect concentration. The invention provides new thinking for antibacterial modification of the titanium alloy, and can effectively promote application of a titanium alloy implant material in the fields of bone tissue repair and regeneration.

The invention discloses postoperation anti-adhesion hydrogel and a preparing method thereof. The hydrogel is prepared from sodium alginate powder, chitosan powder, acrylamide monomers, N,N'-methylene bisacrylamide, calcium sulfate, ammonium persulfate and N,N,N',N'-tetramethylethylenediamine. The preparing method of the high-strength high-tenacity chitosan and sodium alginate compound hydrogel is easy to operate, parameters are controllable, the materials are easy to obtain, and the solvent is nontoxic or low in toxicity and safe to treat and use; the method integrates advantages of the two natural biological materials, and the requirement for postoperation adhesion prevention of patients and the requirement for nursing care and treatment of medical workers can be met well. The hydrogel is soft, can be attached to the skin easily, has good flexibility and can effectively prevent wound surface adhesion and be degraded and absorbed, secondary trauma is avoided, and the hydrogel is expected to become a novel postoperation anti-adhesion material.

The invention relates to bacillus amyloliquefaciens which has stronger phosphate solubilizing and plant growth promoting functions and has a better preventing and treating effect on various plant diseases. According to the bacillus amyloliquefaciens JCD-H-12 with the phosphate solubilizing, disease preventing and growth promoting functions, disclosed by the invention, the preservation number is CGMCC NO.11856, the preservation date is December 10, 2015, and multiple effects of solubilizing phosphate, preventing diseases, promoting the growth, increasing the yield and the quality, having a broad bacteriostatic spectrum and the like are obtained; a bacterial strain and inoculant of the bacterial strain are capable of effectively preventing and treating powdery mildew, tobacco black shank, botrytis blight, rice blast, cucumber fusarium wilt, tomato early blight, sweet pepper anthracnose, watermelon sclerotinia sclerotiorum, wheat scab, watermelon fusarium wilt, phytophthora capsici and the like; a broad-spectrum antibacterial effect is obtained, the effect is stable and durable, and the bacillus amyloliquefaciens can be developed into a bacterial fertilizer and microbial pesticide preparation which integrates phosphate solubilizing with disease preventing and treating.

A compound anti-beta-lactamase antibiotic is prepared from cefuroxime or its salt, sulbactam or its salt, and tazobactan or its salt. Its advantages are broad spectrum and high antibacterial effect.

The invention provides a biocontrol bacterial strain for preventing and treating plant diseases and its bacterial agent, belonging to the field of biological control. The strains used are Gram-negative bacteria, identified as Lysobacter enzymogenes, and the strain code is OH11. Strain OH11 has no flagella but has slippage, can produce various extracellular hydrolytic enzymes including chitinase, β-1,3-glucanase and protease, and can effectively inhibit the growth of fungi and bacteria. The antibacterial zone diameters of strain OH11 against Sclerotinia sclerotiorum and Phytophthora capsici were both greater than 22.0 mm; the antagonism against potato ring rot was stronger, and the diameter of the inhibition zone reached 50 mm. The OH11 strain was inoculated into the seed tank, cultivated to the logarithmic growth phase, and the seed liquid was connected to the production tank for cultivation. The medium used in the production tank was the same as that of the seed tank. The liquid fermentation adopts aerobic submerged fermentation and fed-batch process, the dissolved oxygen is 15%-20%, the fermentation temperature is 30°C, the fermentation time is 72h, and the initial pH value is 7.5. After the fermentation is completed, the culture solution is taken out of the tank and directly packed into liquid dosage forms with plastic packaging barrels or packaging bottles, or subpackaged into solid dosage forms with peat adsorption packaging bags. The biocontrol strain OH11 can effectively control plant pathogenic fungi, bacteria, nematodes and other diseases, and the overall control effect is 50%-70%. In the greenhouse pot experiment, the control effects of OH11 on pepper blight and tomato bacterial wilt reached 83.6% and 86.4%, respectively. Strain OH11 has the characteristics of broad antibacterial spectrum, high activity, and environmental safety. In today's serious pesticide pollution, zymolysobacterium and its bacterial agent will be a good substitute.

The invention discloses a medical super-lubricity antibacterial catheter coating liquid. The coating liquid consists of lubricating liquid and antibacterial substance, wherein the lubricating liquid is prepared through dissolving hydrophilic polymer in organic solvent and adding adhesive polymer at the same time; and the antibacterial substance consists of nano-silver or other nano materials, iodine or iodine compounds, chitin or chitosan and derivatives thereof. The coating liquid is directly soaked or sprayed on a catheter surface through one step when being used, and after solidification, a medical super-lubricity antibacterial catheter is prepared. The coating liquid has double effects of super lubricity and antibiosis, the coating liquid preparation and a coating method are simple, and the coating liquid is easy for mass production. The coated product has strong lubricity, and the coating liquid has an antibacterial function and no drug resistance and can prevent various bacteria and fungi infections and related complications from being generated. The medical super-lubricity antibacterial catheter coating liquid is suitable for the medical field and has good popularization and use values.

The invention provides a high-performance antibiosis wood plastic composite material and a preparation method thereof, and relates to a composite material obtained by blending surface grafting modification vegetable fiber powder and molding powder. The high-performance antibiosis wood plastic composite material comprises components of modification vegetable fiber powder of which the surface is grafted with various germifuga, recycled molding powder and the like. The various activity antibiosis monomers are grafted on the surface of the vegetable fiber powder by high-energy radiation, so that the antibacterial long residual action and mechanical property of the wood plastic composite material are improved obviously. The high-performance antibiosis wood plastic composite material in the invention is prepared from the components by a general method of fusing and blending in plastic processing. The wood plastic composite material has excellent antibacterial long residual action, and obviously improves the interface of wood and plastic in the wood plastic composite material because of the chemistry grafting modification of the surface of the vegetable fiber, and ensures that the material mechanical property and the water absorbency resistance are improved greatly, and can be applied in the fields of indoor or outdoor decoration, furniture, packaging and the like.

The invention provides a lactobacillus plantarum ZJ316 which is separated from excrement of infants and anti-bacterial peptide which is produced by the fermentation of the lactobacillus plantarum ZJ316, namely plantaricin ZJ316, and preparation and application thereof; the plantaricin ZJ316 is a novel lactobacillus anti-bacterial peptide with high efficiency and small molecular; the anti-bacterial peptide has bacteriostatic action of broad spectrum; due to small molecular weight, a lipid bilayer is hard to be crossed so as to form a complex body with small holes to be different from the action mode of nisin; but the anti-bacterial peptide also has sterilizing capacity with high efficiency, is a lantibiotic anti-bacterial peptide with superhigh application and development potential and can be applied to preparing the alternative medicine of feed additives, food preservatives and antibiotic, etc.

The invention provides a toothbrush hair having an anti-bacterial and health-caring function and a preparation method thereof. The toothbrush hair includes the following raw materials, by weight, 75-90% of a polymer, 3-20% of a natural anti-bacterial agent, 1.8-3% of pomegranate seed oil, and 1.2-2% of a coupling agent. The natural anti-bacterial agent is prepared from following components comprising, by weight, 75-90% of loess powder, 4-10% of an extract of commelina communis, 3.5-9% of an extract of herba houttuyniae and 2.5-6% of an extract of caryopteris incana. By means of the technical scheme, the toothbrush hair is produced through various process methods. The toothbrush hair is wide in anti-bacterial spectrum, is high and durable in efficiency and is safe to use, has excellent light-prevention, wear-resistant and aging-resistant performance, has the health-caring effect of increasing fragrance and protecting teeth, is beneficial to environment cleaning and odor eliminating, has the effects of preventing and controlling decayed tooth and periodontal diseases, is good in anti-dirt property, rebound elasticity, flexibility and hydrophobicity, is free of deformation, is long in service life, is low in production cost and is easy to popularize.

The invention discloses an antimicrobial polycarbonate plastic and a preparation method thereof. The antimicrobial polycarbonate plastic comprises the following components in parts by weight: 100 parts of polycarbonate, 0.3-0.5 part of antimicrobial agent and 0.2-0.4 part of dispersant. The antimicrobial agent is one or mixture of nano titanium dioxide, nano silver oxide, polyhexamethyleneguanidine phosphate and N-(trichloromethylthio)phthalimide. The antimicrobial polycarbonate plastic disclosed by the invention can be easily processed into various shapes of interior ornaments of automobiles by an injection molding technique. The antimicrobial polycarbonate plastic disclosed by the invention has strong effects of bacterium control and killing and mold resistance.

The invention discloses a nano silver antibacterial latex pillow or mattress and a preparation method thereof. Tiny air holes are fully distributed on the surface of the nano silver antibacterial latex pillow or mattress, and air is filled into the tiny air holes; and the silver antibacterial latex pillow or mattress has bacterial resistance on aspergillus niger, aspergillus flavus, discolored aspergillus, penicillium citrinum, paecilomyces varioti, herbarium cladosporium, trichoderma viride and chaetomium globasum. The preparation method comprises the following steps of: uniformly mixing nano sliver with natural latex; then respectively adding sulphur, bi(triethoxy propylsilane)tetrasulfide and 2,6-butylethylene-4-methylphenol; uniformly stirring; adding soap and air to generate foams; then adding gelatin; and compressing for moulding. The nano silver antibacterial latex pillow or mattress of the invention combines air permeability, high elasticity and soft touch feeling of the latex with efficient bacterial resistance and broad spectrum sterilizing performance of nano silver and can effectively overcome the defects of easy bacterial generation, difficult air permeation, and the like of a common pillow on the market.

The invention provides a Bacillus coagulans HEW-B379 with a probiotic effect. The above strain is named as HEW-B379, and the preservation number of the strain is CGMCC No.12553. The Bacillus coagulans HEW-B379 has a substantial probiotic property, and can effectively inhibit growth breeding of enteropathogenic Escherichia coli, Staphylococcus aureus, Salmonella typhi, salmonella, Shigella, Proteus species, Shewanella putrefaciens and Pseudomonas aeruginosa. The Bacillus coagulans HEW-B379 has strong stress resistance, can resist high temperature and simulated gastric juice and simulate bile salt environment, can keep the survival rate of 99-100%, and can effectively adjust microbial balance of animal intestinal tracts, inhibit growth of harmful microbes, promote nutrition absorption of animals, improve the conversion rate of a feed and improve the productivity of the animals.

The invention discloses a green antimicrobial cleanser essence as well as a preparation method and application thereof. According to the invention, the green antimicrobial cleanser essence is prepared from an antimicrobial agent, 15.0-45.0% of natural surfactant, 0.1-0.3% of chelating agent, 2.0-5.0% of thickening agent and 0.3-0.9% of composite antimicrobial agent, wherein the antimicrobial agent is a composition of nano silver and natural plant extractives at a mass ratio of 1:5 to 1:1. The antimicrobial activity of the cleanser essence is greatly improved due to the antimicrobial synergistic effect of nano silver and the natural plant extractives; the cleanser essence has the following characteristics of wide antimicrobial spectrum and high antimicrobial efficiency and can be used for removing dirt and pesticide residues as well as peculiar smell while sterilizing effectively, so that the purpose of removing dirt, pesticide residues, harmful microorganisms and peculiar smell at one step is achieved. The preparation method is simple in preparation process, low in cost and capable of being applied to industrial mass production. The prepared green antimicrobial cleanser essence is high in anti-microorganism efficiency, free of toxicity and stimulation, environment friendly, bio-gradable and free of residues after being used so as to be used for cleaning dishes, fruits and vegetables.

The invention discloses a method for preparing a contamination-resistant composite reverse osmosis membrane. The method comprises the steps of (a) preparing a polysulfone support membrane; (b) preparing an aromatic polyamide reverse osmosis composite membrane by using the polysulfone support membrane obtained in Step (a); and (c) grafting chitosan on the surface of the aromatic polyamide reverse osmosis composite membrane obtained in Step (b). According to the method for preparing a contamination-resistant composite reverse osmosis membrane, chitosan is grafted on the surface of the polyamide reverse osmosis composite membrane through a chemical treatment method, so that hydrophilicity of the surface of the membrane as well as the water flux of the membrane is improved; meanwhile, contaminations such as hydrophobic organic matters and transition metal ions can be prevented from being absorbed on the surface of the membrane, thereby greatly improving the anti-pollution capability of the membrane; in addition, chitosan has broad-spectrum antibacterial property, so that the resistance of the membrane against microbial contamination is improved.

The invention provides an antiseptic viscose fiber. It is spinned by the silver antiseptic agent and the cellulose sulphonic acid ester. The silver antiseptic agent is 0.5-5% weight of the cellulose. The product has the good antisepsis and the detergent resistance.

The invention discloses a marine bios sterilization solution. The effective sterilization ingredients of the sterilization solution are prepared from beta-chitosan quaternized hyaluronic acid derivative, algal polysaccharide derivative, alpha-spiral cecropin serving as a marine organism, biological enzyme and cationic polyguanidine by a special technology. The sterilization solution is suitable for sterilization of restaurants, hotels, hospitals, marketplaces, banks, schools, kindergartens, households, offices and journey, can be used as a remedial measure after hand washing in hospitals, nursing centers, nursery centers, snack bars, kitchens and bathrooms, or can be used for sterilizing skin wounds and cleaning vulva and the like, can effectively control the propagation of typhoid fever, flu, dysentery, pinkeye, gonorrhea and various skin diseases, and has no stimulus or corrosion to the skin. The marine bios sterilization solution is characterized by comprising the following components in percentage by weight: 1.0 to 2.0 percent of beta-chitosan quaternized hyaluronic acid derivative, 0.5 to 1.0 percent of algal polysaccharide derivative, 6.0 to 8.0 percent of alpha-spiral cecropin serving as a marine organism, 0.5 to 1.0 percent of biological enzyme, 3.0 to 4.0 percent of cationic polyguanidine and the balance of deionized water.

The invention discloses a green mud crab antibacterial peptide Sphistin and application thereof, relates to the technical field of genetic engineering of crustaceans, and provides the green mud crab antibacterial peptide Sphistin and the application thereof. A molecular formula of the green mud crab antibacterial peptide Sphistin is C170H293N61O46S1 and molecular weight of the green mud crab antibacterial peptide Sphistin is 3,959.61 Dalton. The antibacterial peptide Sphistin consists of 38 amino acids, is derived from a part of sequences at end N of green mud crab histone 2A protein and is apolypeptide with an antibacterial function. By adopting the conventional solid-phase chemical synthesis method, the green mud crab antibacterial peptide Sphistin with purity of over 95 percent can beobtained. The green mud crab antibacterial peptide Sphistin has an obvious antibacterial effect on various gram negative bacteria and gram positive bacteria, has a broad antibacterial spectrum and high sterilization rate, shows extremely high medical value and is excellently applied to preparing antibacterial agents.

The invention relates to a Bacillus subtilis strain YB-05, and a preparation method of an inoculant of the Bacillus subtilis strain YB-05. The Bacillus subtilis strain YB-05 is preserved at China General Microbiological Culture Collection Center, and has a preservation number of CGMCCNO.6498. The microbial inoculant is a pulvis prepared through the spray dry preparation of a fermentation solution of the Bacillus subtilis strain YB-05. The YB-05 strain and its inoculant have the advantages of wide antibacterial spectrum, good antimicrobial effect, and strong inhibition effects on the wheat take-all disease, tomato Botrytis cinerea, wheat sheath blight fungi, Phytophthora melonis and the like; and the inoculant has the advantages of high efficiency, non-toxicity, simple use, and no environmental pollution.

The invention discloses bacillus methylotrophicus F7 and an application thereof. The invention aims at providing a strain which has a plurality of beneficial properties, namely producing siderophore, cellulase and protease, producing auxin, producing ammonia and the like; the strain not only can be used for effectively inhibiting various pathogenic bacteria such as ralstonia solanacearum, fusarium oxysporum f.sp.cubense, colletotrichum gloeosporioides, fusarium oxysporum f.sp cucumerinum but also can promote plant growth. In accordance with the technical scheme, the bacillus methylotrophicus F7 is preserved in China General Microbiological Culture Collection Center (CGMCC) on February 1, 2016, with preservation number of CGMCC No.12124; in addition, five surfactin homologs, six fengycin homologs and three iturin homologs, which have an antibacterial effect, are extracted from fermentation liquid of the bacillus methylotrophicus F7; and the bacillus methylotrophicus F7 belongs to the field of agricultural biotechnology.

The invention discloses a streptomyces microflavus. The streptomyces microflavus is the streptomyces microflavus NMG2-4-8, and the preservation number thereof is CGMCG No.3442. The streptomyces microflavus is separated and screened from alfalfa healthy tree rhizosphere soil for the first time in the invention, and experiments prove that the streptomyces microflavus has remarkable antagonistic action for 18 pathogenic fungi and 9 bacteria and broad antibacterial spectrum. The streptomyces microflavus has strong inhabiting action for crop pathogenic bacteria, such as alfalfa downy mildew and the like, shows a good disease prevention effect for the alfalfa downy mildew, powdery mildew, brown spots, stemphylium leaf spot disease, root rot disease and the like, and indicates that the bacterial strain has broad application prospect in the biological prevention and cure fields of alfalfa diseases.

The invention discloses an antibacterial natural latex product based on a quaternary ammonium salt antibacterial agent and a preparation technology of the antibacterial natural latex product, and belongs to the technical field of latex materials. The antibacterial natural latex product is prepared from the following components by weight: 90 to 100 parts of natural latex, 1 to 9 parts of sulfur, 1 to 5 parts of a vulcanization accelerator, 1.5 to 2 parts of an anti-aging agent, 1 to 6 parts of zinc oxide, 0.5 to 2 parts of sodium fluosilicate, 1 to 3 parts of potassium castorate, 0.1 to 2 parts of potassium oleate, 0.5 to 1 part of potassium permanganate and 0.1 to 3 parts of the quaternary ammonium salt antibacterial agent. The antibacterial natural latex product is based on the antibacterial characteristic of a low-concentration quaternary ammonium salt compound. The adopted quaternary ammonium salt compound has the advantage of stable performance, and the compound is tightly combined with latex polymer molecules and cannot permeate the skin of people or an animal by changing the physicochemical property of material surface. The latex product prepared in the invention has the advantages of high antibacterial property, hygiene, high practicability and the like, and has a broad market prospect.

The invention discloses enterococcus faecalis HEW-A131 which is high in thermal resistance, wide in acid-alkali resistance range, high in stress resistance and relatively high in probiotic property. The strain is preserved in the China General Microbiological Culture Collection Center on June 17th, 2014, the preservation serial number is CGMCC NO.9353, and the classification name is enterococcus faecalis. The enterococcus faecalis HEW-A131 has excellent microorganism characteristics, remarkable probiotic property and stress resistance and super high fermentation property, not only is the utilization efficiency of feed of animals increased, but also the cost is reduced, moreover the stability of the environment inside the alimentary canals of animals is greatly improved, the adsorption and utilization of nutrition are promoted, the animal growth is promoted, the production performance, immunity and breeding property of the animals are remarkably improved, the production cost is lowered, and the economic benefits are increased.

In the present invention, China cypress paper is painted with the ink and rolled, so that wide-spectrum antiseptic ink with inorganic antiseptic, organic antiseptic and Chinese medicinal antiseptic is painted on the surface to produce wide-spectrum antiseptic China cypress paper. The present invention features the ink, which consists of modified rosin, PVA, dibutyl phthalate, butyl aldehyde condensate, anatase type titania, medical alcohol, ferrite yellow calcium carbonate and talcum powder; has silver ion, copper ion, Ampicillin sodium and Eight Health Restoring Medicine mixture; and is produced through reaction, grinding, and dispersion.