6 results about "Typhoid fever" patented technology

In one aspect, the disclosure relates to compositions and methods for dispersing exiting Salmonella biofilms and inhibiting formation of Salmonella biofilms. In various aspects, the disclosed compositions can be used in methods of treating a persistent Salmonella infection, including an asymptomatic infection. Such infections can colonize a variety of tissues, including the gall-bladder. Also disclosed are methods of treating typhoid fever. Also disclosed are methods for mitigating or preventing secondary outbreaks of typhoid fever by treating asymptomatic subjects who had been symptomatic for typhoid fever at a previous time. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

The invention discloses a salmonella H: i epitope specific monoclonal antibody and application thereof, the salmonella H: i epitope specific monoclonal antibody is secreted by hybridoma cells with the preservation number of CCTCC NO: C202645, and the antibody has the advantages of high titer and strong specificity. According to the blocking ELISA detection kit constructed by the antibody and the detection method of the blocking ELISA detection kit, the antibody containing H: i antigen epitope salmonella in infected animal serum can be specifically detected, the antibody does not react with antibodies containing no H: i antigen epitope salmonella and non-salmonella, the sensitivity, specificity and stability are good, and the detection method is simple and convenient. And a new method is provided for direct serological detection of H: i antigen epitope-containing salmonella infection of mouse typhimurium, kafenkii and the like.

The invention discloses warm-tonifying complex sugar and application thereof, and the warm-tonifying complex sugar comprises the following components in percentage by mass: 1.5-15% of kudzuvine root, 0.9-9% of dried ginger, 0.6-6% of clove and 70-97% of cane sugar. The sugar special for the ice cream can reduce the phenomenon that the current ice cream causes negative typhoid fever, abdominal pain and diarrhea to human bodies to affect appetite, so that the purposes of relieving summer-heat, quenching thirst and taste, warming the stomach, intestine and uterus, effectively protecting normal operation of digestive systems of the human bodies and protecting the bodies from being injured are achieved.

The present disclosure relates to novel immunogenic monovalent and multivalent polysaccharide-protein conjugate vaccine compositions comprising a polysaccharide selected from Salmonella serovar strains S. typhi; S. paratyphi A; S. typhimurium and S. enteritidis and alternative improved methods of polysaccharide fermentation, polysaccharide purification, polysaccharide-protein conjugation and stable formulation. The present disclosure further relates to methods for inducing an immune response in subjects against Salmonella and non-typhi related diseases and / or for reducing or preventing Salmonella typhi and non-typhi related diseases in subjects using the compositions disclosed herein. The vaccine elicits bactericidal antibodies and is useful for prevention of gastroenteritis, enteric and typhoid fever.

The invention discloses a classic famous formula ephedra decoction and a preparation method thereof, the ephedra decoction is derived from the theory of typhoid, is aboriginal by famous doctors in East Han, is a prescription created by Zhang gutta-percha and used for treating solar typhoid exterior syndromes, and the medicine is prepared from 9g of ephedra, 6g of cassia twig, 3g of liquorice and 6g of scalded bitter apricot kernels. The medicine has the effects of inducing sweat, dispelling exogenous evils, freeing lung and relieving asthma, and is good in treatment effect, lasting in effect and free of toxic and side effects; and the ephedra decoction is prepared into granules by using a modern preparation technology, so that the compliance of a patient to the medicine is improved, the production process is simple, and the production cost is low.

In one aspect, the disclosure relates to compositions and methods for dispersing exiting Salmonella biofilms and inhibiting formation of Salmonella biofilms. In various aspects, the disclosed compositions can be used in methods of treating a persistent Salmonella infection, including an asymptomatic infection. Such infections can colonize a variety of tissues, including the gall-bladder. Also disclosed are methods of treating typhoid fever. Also disclosed are methods for mitigating or preventing secondary outbreaks of typhoid fever by treating asymptomatic subjects who had been symptomatic for typhoid fever at a previous time. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.