The invention provides an application of a
drug composition in the preparation of drugs for preventing
salmonella infection in laying hens, improving
egg laying performance of the laying hens, reducing the amount of
salmonella in shells and contents of eggs and improving quality of the eggs of the laying hens. The
drug composition comprises, by weight, 20-50 parts of gallnut
tannic acid and 10-30parts of
glycine. The
drug composition has the advantages of green safety and no tolerance by taking 'source conditioning' as the core; replacing
antibiotics, the drug composition can effectively inhibit and kill
salmonella, eliminate endotoxemia caused by bacterial death and release of endotoxin, adjust the body's
immune defense, purify salmonella from the laying hens, reduce horizontal spread ofsalmonella and egg-borne
contamination caused by potential endogenous displacement of chickens, improve
egg laying performance and the quality of the eggs and effectively avoid
food safety problems caused by the egg-derived salmonella.