234 results about "Infection resistance" patented technology

The invention relates to a method for preparing an anti-stress agent used for fishing, belonging to the technical field of aquatic product compound feed. The method is characterized in that glutamine dipeptide, rhubarb extract, vitamin C, vitamin E, potassium chloride, sodium chloride, anhydrous dextrose and a carrier are taken and fully mixed to be ground and prepared into dry powder. The raw materials of the invention has the advantages of stable source, simple preparation, wide material source and low cost; due to the stress principle of fish body, the anti-stress agent not only supplements Chinese herbal medicines, but also complements western medicine of glutamine dipeptide; the combination of Chinese herbal medicines and western medicine regulates the stress of fish body, and appropriately supplements the loss of Na<>, K<> caused by stress to control the stress of fish body. When in use, the anti-stress agent can be added into feed and directly splashed; the immunity and inhibiting ability of fish body can be improved, the capacity of resisting high temperature and high density as well as infection resistance for resisting hydrophile aeromonas can be improved, and the growth of the fish body can be accelerated.

The invention provides a novel biological-material complex patch which is of a laminated structure comprising a basic layer and an additional layer. The novel biological-material complex patch is characterized in that the basic layer is an patch made from an artificial synthetic material; the additional layer is a biological patch made from an extracellular matrix/acellular tissue matrix material, or a synthetic-material patch made from an artificial synthetic biological material or the artificial synthetic biological material and an artificial synthetic degradable material; and the basic layer and the additional layer are integrated through a surgical suture or a medical adhesive or other methods. The biological-material complex patch has the advantages of easiness for peripheral tissue growth and angiogenesis, adhesion prevention, degradability, good infection resistance and the like of the biological material and the advantages of easiness for tissue growth by of a big mesh, excellent infection resistance, difficulty for generating hydrops, non-degradability, high late mechanical strength and durability of the artificial-synthetic-material patch, adopts a simple production method, is more effective after being applied in clinic, and ensures recent and late relapse and infection rates to be lower.

The invention discloses a channel catfish immunity enhancing feed, which comprises the following components in parts by weight: 5-14 parts of meat and bone meal, 15-25 parts of rapeseed meal, 20-40 parts of de-hulled soybean meal, 0.2-0.5 part of choline chloride, 15-22 parts of wheat middling, 0.5-1 part of soybean oil, 0.2 part of vitamin premix, 0.15 part of mineral premix, 1-2 parts of calcium dihydrogen phosphate, 0.01-0.03 part of plant enzyme, 0.05-0.1 part of cholate substances, 0.03-0.06 part of a toxin adsorbent, 0.1-0.3 part of a natural plant compound and 0.1-0.3 part of a polysaccharide compound. According to the immunity enhancing feed disclosed by the invention, nonspecific immunity of the channel catfish is enhanced through various compounds, and through reasonable proportioning of various natural plants and the polysaccharide components, nonspecific immunity of the channel catfish is significantly improved and infection resistance of the fish is enhanced; and meanwhile, growth performance of the fish is improved and a food coefficient is reduced.

The invention belongs to the field of biological agents and discloses triple probiotics viable bacteria powder obtained by whole oat mixed solid-state fermentation utilizing various probiotics direct-adding reagents. The triple probiotics viable bacteria powder contains bifidobacterium lactis V9, lactobacillus plantarum P-8 and lactobacillus casei Zhang, and is prepared by taking whole oat powder as a fermentation substrate, and has excellent gastrointestinal tract digestive juice endurance capacity, is capable of improving a bacterial community structure of human intestinal tracts, capable of regulating blood lipid metabolism and capable of improving pathogenic infection resistance of intestinal tracts, and effectively prevents and relieves irritable bowel syndromes such as diarrhea, constipation, stomachache, abdominal distension.

The invention discloses a method for preparing a nano-silver thread, which comprises the operation steps of: preparing 1 mmol of silver nitrate solution and 2 mmols of sodium borohydride solution respectively, then preparing the two solutions into a nano-silver colloid solution, then preparing the nano-silver colloid solution into a nano-silver gelatin solution, performing heating and concentration on the nano-silver gelatin solution, then performing water bath heat preservation on the concentrated nano-silver gelatin solution to ensure that the mixed gelatin solution is in a melted state, then soaking a suture which can be absorbed by human bodies into the nano-silver gelatin solution for a period of time, then uniformly drawing out of the suture at a preset rate, and naturally drying the suture; and thus ensuring that the nano-silver gelatin mixed solution with corresponding viscosity forms a layer of thin glue film on the suture to obtain the nano-silver thread. The method has simple and easy operation steps; used instruments are commonly used experimental vessels; and the prepared nano-silver wire has the surface silver content of between 15 and 300 ng/cm, is used as a novel thread body for catgut embedding therapy, can play roles in infection resistance, sterilization, inflammation diminishing and the promotion of wound healing of surface element-silver, and can increase the therapeutic effect, repair and stimulate the regeneration of organisms when embedded into tissues for a long time.

The invention relates to the technical field of feed and in particular to a feed for phasianus colchicas. The feed comprises the following raw materials in percentage by weight: 50-60% of corn flour, parched soybean flour 15-20% of parched soybean flour, 8-10% of rye bran, 1-2% of pea flour, 25-30% of bean cake, 1-2% of chicken viscera meal, 1-2% of hydrolyzed feather meal, 0.5-1% of raspberry, 1-2% of pumpkin seed, 0.5-1% of sea buckthorn fruit, 1-2% of stone meal, 1-2% of crab shell meal, 1-2% of pine moth powder, 0.5-1% of peeled shrimp, 1-2% of wasp powder, 1-2% of molasses grass seed, 5-6% of young perilla leaf, 1-2% of honeysuckle, 1-2% of houttuynia cordata, 2-3% of premix, an appropriate amount of table salt and 0.2-0.5% of a feed attractant. The feed for phasianus colchicas, provided by the invention, is designed according to the feed intake behavior of phasianus colchicas, is based on the conventional feed materials with the addition of plant fruits and branches as well as leaves (such as molasses grass seed, sea buckthorn fruit, raspberry and perilla leaf) which improve the palatability of the feed, and traditional Chinese medicine (such as honeysuckle and houttuynia cordata) which can improve the disease resistance and bacterial infection resistance of phasianus colchicas and reduce the incidence of diseases. The incidence of diseases in phasianus colchicas fed on the feed can be effectively controlled, the weight gain is fast, the hair color is bright, the feed intake behavior is active, and the benefit of farmers is high.

A nursery pig feed the following materials by weight: 600-650 parts of corn, 100-150 parts of dehulled soybean meal, 15-25 parts of corn protein powder, 20-30 parts of imported fish meal 65% CP, 27-32 parts of blood plasma protein powder, 23-28 parts of soybean oil, 130-170 parts of premix, 22-26 parts of Radix Pulsatillae, 5-10 parts of Radix Sophorae Flavescentis, 120-180 parts of Radix Astragali, 5-10 parts of Cortex Phellodendri, 10-20 parts of Radix Codonopsis, and 0.5-1.5 parts of mildew preventive. The feed contains complete nutrition including rich proteins, amino acids, vitamins and minerals needed by animals, improves immunity, digestion, absorption and infection resistance of nursery pig, lowers feed-meat ratio, and improves feed repay.

The invention discloses a medical titanium alloy surface coating and a preparation method thereof. The titanium alloy surface coating is Ti-27Nb-6Zr-5Mo alloy surface Ta or Ta-Cu-Zn composite coating.A Ti-27Nb-6Zr-5Mo alloy surface is polished; and a nano oxidation tube is prepared on the alloy surface with an anodizing method, then a layer including tantalum (Ta), copper (Cu) and Zinc (Zn) is sprayed to the surface of the nano tube with the plasma spraying technology, and the composite bio-coating is prepared. Medical titanium alloys are compared, the nano oxidation tube is attached to the alloy surface, Ta and TaCuZn are sprayed to the surface of the oxidation tube, the corrosion resistance, the biological activity and the antibacterial performance are improved, the bio-activity and thebonding strength of the coating and an alloy substrate can be improved through an intermediate nano oxidation layer, the corrosion resistance of the coating can be improved due to Ta on the surface,and the bacterial infection resistance of the medical titanium alloys can be improved through a trace of continuously-separated Cu and Zn ions in the coating. The novel coating material is beneficialto solving the problems that an existing bone implant material is poor in bio-activity, insufficient in corrosion resistance and antibacterial performance and the like.

The invention discloses a bionic polymer, a method for preparing a durable double-bionic polymer coating and an application thereof, wherein the method comprises the following steps: the bionic polymer with side groups containing zwitterionic groups W, amino hydrochloride S and quaternary ammonium cation groups T and dopamine are dissolved in a solvent in sequence to prepare a polymer-dopamine alkalescent aqueous solution, then the different substrates are in the polymer-dopamine alkalescent aqueous solution, and the durable double-bionic polymer coating is obtained by leaching and drying. Theobtained coating has the advantages of high light transmittance, good hydrophilicity, strong universal base material, excellent coating stability, good biomolecule adhesion resistance and antibacterial performance, and simple preparation process; one-step dipping and coating method is convenient and efficient, green and mild property; the surface of the material has the advantages of long-term biological pollution resistance, bacterial infection resistance and high biocompatibility; the coating is suitable for coating the surfaces of medical equipment, diagnosis and treatment instruments, implants, drug delivery systems, contact lenses, corneal shaping lenses and the like with various shapes and materials and high light transmittance requirements.

The present invention relates to the field of protein, and in particular relates to biologically active polypeptide WNIPMGLIVNQ and a preparation method and the application thereof, and the amino acid sequence of the biologically active polypeptide WNIPMGLIVNQ is Trp-Asn-Ile-Pro-Met-Gly-Leu-Ile-Val-Asn-Gln. In vitro antioxidant experiments and in vitro immune function promotion experiments verify the biologically active polypeptide WNIPMGLIVNQ has good antioxidant biological activity and immunity regulating function, on the one hand, the biologically active polypeptide WNIPMGLIVNQ has good antioxidant activity to remove free radicals in the body and improve the quality of life; on the other hand, the biologically active polypeptide WNIPMGLIVNQ can enhance the in-vitro proliferation ability of lymphocytes and macrophages to promote the increase of macrophage induced nitric oxide, the biologically active polypeptide WNIPMGLIVNQ can improve the external pathogen infection resistance of the body and reduce the disease incidence of the body, and has very important significance for development of food, health care products and drugs with immune function regulating and antioxidant function.

A boron coating is applied to selected surfaces of surgical devices, including orthopedic prosthetic alloys and surgical tools to improve sliding wear and provide other benefits. The coating may be applied to CoCrMo, stainless steel, or titanium alloy components of artificial hips, knees, shoulders, and other articulating joints, which bear on wear partners and which experience rubbing wear during use of the joint. In such cases, the coating is preferably applied in particular to the rubbing wear surface of the CoCrMo alloy component to reduce wear of either the alloy component or the mating polymer component, for corrosion improvement, for biocompatibility, or for improvement in infection performance of the device. The boron coating may show evidence for reactive bonding to the substrate, which may include evidence of in-diffusion or of interdiffusion between the boron and the substrate material. The inventive boron or boron-based coating may also be applied to non-wear surfaces of the alloy to improve performance in terms of biocompatibility or infection resistance, as for hip joint stems or other fixation parts of devices. The inventive coating may also be applied to medical devices such as surgical tools to provide a hard, sharp cutting surface. A method of making boron-coated medical devices is also disclosed.

The invention provides a biological repair tablet for herniae and a preparation method thereof. The repair tablet uses small intestine submucosa tissues of inbred line animals without cell and DNA (deoxyribonucleic acid) components as the raw material, completely reserves the extracellular matrix component and structure, and has a micropore structure. The preparation method of the repair tablet comprises the following operation steps: determination of animal source, pretreatment and rough cleaning of small intestine tissues, virus inactivation, cell removal, DNA removal treatment, formation, packaging and sterilization. The biological repair tablet for herniae prepared by the method uses an inbred line animal as an animal source, and thus, the hereditary features are pure, stable and uniform, thereby radically ensuring the stability and uniformity of different batches of products; and the biological repair tablet for herniae has fewer animal source DNA residues, completely reserves the three-dimensional structure of natural ECM, and has the advantages of low immune source property and high infection resistance.

The invention relates to recombinant protein of A1S_1523 as well as a preparation method and application of the recombinant protein. The recombinant protein comprises A1S_1523 mature peptide, and an amino acid sequence of the recombinant protein is shown in SEQ ID NO. 3. The recombinant protein disclosed by the invention is high in expression quantity and convenient to separate and purify, is efficient and safe, can be directly matched with adjuvants for use, and can be used for preparing acinetobacter baumannii infection resistant subunit vaccines and related detection kits; proven by animal experiments, gene engineering recombinant monovalent subunit vaccines have good immune protective effects on acinetobacter baumannii infection resistance; and the recombinant protein can be used for laying a foundation for further researching combined vaccines and multi-subunit fusion vaccines, and can also play important roles in the development and application of prevention and treatment vaccines and diagnostic kits.

The invention discloses a molecular marker of rice blast resistant gene Pigm of Gumei 4 and an application thereof. The molecular marker comprises a specific molecular marker Pigm-4 of Gumei 4, wherein the molecular marker Pigm-4 comprises the DNA fragments different in the 10436119-10436192bp of the chromosome 6 of Nipponbare genome, while the sequence of the section of Gumei 4 is lost; and the forward and reverse primers of the Pigm-4 primer pair are shown by SEQ ID No:2 and SEQ ID No:3 respectively. The forward and reverse primers of the Pigm-2 of the forward molecular marker primer pair of Pigm gene are shown by SEQ ID No:4 and SEQ ID No:5 respectively. The invention also discloses an application of the molecular marker in improving the rice blast infection resistance of rice through a molecular marker assisted selection of rice blast resistant rice breeding and a molecular marker assisted selection method. The molecular marker disclosed by the invention has good specificity and realizes tighter interlocking with a target area.

The invention relates to the field of fish medicine preparations, in particular to Sanhuang supper micropowder as well as a preparing method and applications thereof. The supper micropowder comprises in percentage by weight as follows: 25-35% of baical skullcap roots, 25-35% of amur cork tree bark, 25-35% of rhubarb and 5-10% of indigowoad leaves. The Sanhuang supper micropowder has effects of clearing heat, cooling blood, resisting viruses and detoxifying, plays powerful antibacterial, disinfection and antiviral roles in water bodies and pathogenic bacteria of aqueous animal (gills, body surfaces and the like) tissue and is particularly used for mainly treating bacterial enteritis caused by pseudomonas, vibrio, aeromonas hydrophila and Edwardsiella in the aqueous animals. Tests prove that the Sanhuang wall-breaking supper micropowder can improve and treat white excrement enteritis of penaeus vannamei boone and septicemia of Micropterus salmoides to a certain extent, can enhance the aeromonas hydrophlia infection resistance of the Micropterus salmoides and is a novel fish medicine for effectively protecting intestinal tracts and preventing bacterial enteritis in the aqueous animals, and the use amount can be significantly decreased by 2-3 times.

The invention discloses suckling pig feed and a preparation method thereof, belonging to the technical field of a livestock feed. The suckling pig feed consists of the following components in parts by weight: 26-28 parts of corns, 10-12 parts of extruded corn powder, 4-6 parts of extruded soybean meal, 3-4.5 parts of steam fish meal, 8-8.8 parts of fermented soybean meal, 10-12 parts of extruded soybean, 3.6-4.2 parts of soybean milk powder, 6-6.5 parts of organic calcium lactate, 8-8.6 parts of whey powder, 2.8-3.2 parts of plasma protein powder, 2.6-3.4 parts of whole milk powder, 3-4 parts of glucose, 0.3-0.45 part of calcium hydrogen phosphate, 0.3-0.5 part of edible salt, 1.2-1.5 parts of soybean oil, 10-12 parts of wheat midding and 3-5 parts of a premix. The suckling pig feed disclosed by the invention is complete in nutrition, free from hormone and residue of harmful ingredients, and is capable of effectively improving immunity and infection resistance of suckling pigs, enhancing digestion and absorption functions of the suckling pigs, greatly reducing the death rate of the suckling pigs and shortening a suckling period, so as to bring about benefit for next breeding of sows. The feed not only can meet growth demand of the suckling pigs, but also can avoid over capacity and waste, thus effectively saving resources.

The invention relates to a rapid haemostat using mipor starch with a high specific surface area as a main raw material and a preparation process thereof. The rapid haemostat capable of being absorbed by a human body is prepared by using the mipor starch with the high specific surface area as the raw material and adding growth factors stimulating the rapid healing of a wound and an antimicrobial with diminish inflammation and infection-resistant effects. The haemostat not only can more rapidly and effectively arrest bleeding, but also can effectively accelerate the healing, the diminish inflammation and the infection resistance of the wound.

The invention relates to the technical field of gene engineering, in particular to an immune enhanced gene vaccine of a hepatitis B virus core antigen (HBcAg). The vaccine is an immune stimulating complex (ISCOM) vaccine consisting of HBcAg and OX40 ligand (OX40L) dual-gene co-expression recombinant eukaryotic vector, saponin Quil A, cholesterol and lecithin. The vaccine can promote immune response of specific T cells of the HBcAg and efficiently induce the anti-virus replication capacity of immune cells, and has good application prospect in the field of hepatitis B virus infection resistance. The invention also relates to a preparation method for the vaccine with simple and convenient operation and low cost.

The invention discloses a high-efficiency hair care cosmetic and a preparation method thereof, and belongs to the technical field of cosmetic preparation. The cosmetic comprises the following main raw materials: humifuse euphorbia herb, shrubalthea bark, Polygonum aviculare, radix ligustici sinensis, phellodendron bark, Mangnolia officinalis, chrysanthemum flower, gardenia, catechu, chaulmoogra, Cyrtomium fortunei, radix ampelopsis, stemona, pomegranate rind, morning glory seed, southernwood, dark plum, pasqueflower, Lemna minor, tea bran, lysozyme, sericin, hydroxylated soybean lecithin, polyoxyethylene fatty acid ester and modified chitosan. The hair care cosmetic disclosed by the invention has high efficiency and safety, has a remarkable hair care effect, has the favorable effects of sterilization, bacterium resistance and itching relief, improves the infection resistance of hair, can effectively prevent and control phenomena such as head louse appearance and the like on the hair, and exerts favorable hair care action, thereby being worthy of popularization and application.

The invention provides a biological repair tablet for endocranium and a preparation method thereof. The repair tablet uses small intestine submucosa tissues of inbred line animals without cell and DNA (deoxyribonucleic acid) components as the raw material, completely reserves the extracellular matrix component and structure, and has a micropore structure. The preparation method of the repair tablet comprises the following operation steps: determination of animal source, pretreatment and rough cleaning of small intestine tissues, virus inactivation, cell removal, DNA removal treatment, formation, packaging and sterilization. The biological repair tablet for endocranium prepared by the method uses an inbred line animal as an animal source, and thus, the hereditary features are pure, stable and uniform, thereby radically ensuring the stability and uniformity of different batches of products; and the biological repair tablet for endocranium has fewer animal source DNA residues, completely reserves the three-dimensional structure of natural ECM, and has the advantages of low immune source property and high infection resistance.

The invention relates to medical glove wearing disinfecting equipment, which is characterized by comprising a disinfecting box (1) which is provided with a disinfecting device (6) inside, wherein a through hole for mounting a glove sleeve fixing ring (2) is formed in one side of the disinfecting box (1); the sleeve end of a glove (3) is fixedly arranged on the disinfecting box (1) by virtue of the glove sleeve fixing ring (2) which can dislocate automatically, and the finger sleeve end of the glove (3) is located inside the disinfecting box (1); an air bellow (5) is additionally arranged on one side of the disinfecting box (1) and the air source of the air bellow is supplied from an air pump (4); and the air outlet of the air bellow (5) is aligned to one side of the disinfecting box (1) mounted with a glove sleeve. The equipment disclosed by the invention can completely prevent cross infection which possibly generates when the glove is worn in one hand, and meanwhile, the equipment has a disinfecting function; and the equipment is high in using efficiency, strong in infection resistance, practical and convenient.

Disclosed herein is an implantable medical device including an antimicrobial layer. The antimicrobial layer may include a first distinct size of silver nanoparticles, a second distinct size of silver nanoparticles, and a third distinct size of silver nanoparticles. The antimicrobial layer extends over a surface of the implantable medical device, and, in some instances, the surface of the implantable medical device may serve as a substrate on which the antimicrobial layer is deposited.

The invention discloses a skin-wound magnetic stapler capable of enhancing natural healing of wounds. The skin-wound magnetic stapler comprises two stripy supporting frames which are arranged respectively along the two sides of the wound and have certain hardness, wherein each stripy supporting frame is internally provided with a hard base containing magnetic stones or magnetic substances, or a soft base containing soft articles including paper, textile fabric, plastic and leather for supporting the magnetic stones or the magnetic substances; the magnetic stones or the magnetic substances are arranged in the hard-base or soft-base frame, and the frame is larger than or equal to a magnetic body; the magnetic body is embedded on the hard-base or soft-base frame by a plurality of fulcrums, or is completely wrapped by the hard base or the soft base. The skin-wound magnetic stapler disclosed by the invention has the advantages that the magnetic force is adopted as kinetic energy, and in surgery, the skin wound does not need to be sutured and the extruding force of the two sides of the tissue of the skin wound is balanced, so that secondary injury to the skin wound can not be caused; wound cleaning, dressing change and drainage for the wound are convenient, and no blockage and hindering are caused for operation of a doctor; blood circulation, inflammation resistance and infection resistance of skin wound edges and wound base tissues also can be improved, and the natural healing can be enhanced.

The invention relates to a cultivation method for ganoderma lucidum with functions of moistening a lung and protecting health. A cultivation medium of the ganoderma lucidum is prepared from the following components in parts by weight of 50-60 parts of seasame chips, 20-25 parts of bagasse, 10-15 parts of chestnut shelsl, 10-15 parts of dry fermented cow dung, 5-6 parts of bran, 6-8 parts of corn flour, 4-5 parts of phaseolus radiatus, 1-2 parts of chilli seeds, 5-7 parts of shrimp shell meal, 4-6 parts of zeolite powder, 1-2 parts of quick lime, 1-2 parts of gypsum powder, 0.5-1 part of white sugar, 0.3-0.5 part of calcium carbonate, 0.5-1.0 part of calcium superphosphate, 0.8-1.0 part of magnesium sulfate, 0.01-0.02 part of potassium sulphate, 0.01-0.02 part of vitamin C and 15-20 parts of lung-moistening Chinese herbal medicine extraction solution. The components are mixed according to the proportion; water is added into the mixer and uniformly mixed; and then bagging, sterilizing and inoculating are performed to obtain the ganoderma lucidum. The ganoderma lucidum cultivated by the cultivation method disclosed by the invention has the advantages of abundant nutrition, high contents of trace elements and vitamin, the functions of moistening the lung and protecting the health as well as strong infection resistance and high yield during the fruiting period of the ganoderma lucidum.