53 results about "Pulsatillae" patented technology

The present invention provides a method for constructing a characteristic spectrum of Pulsatilla chinensis medicinal materials, standard decoctions, or traditional Chinese medicine granules, comprising the following steps: preparing a test solution from the Pulsatilla chinensis medicinal materials, standard decoctions, or traditional Chinese medicine granules; and subjecting the test solution to ultra-high performance liquid chromatography analysis. The ultra-high performance liquid chromatography analysis conditions include: mobile phase A being a mixture of acetonitrile and methanol, mobile phase B being an aqueous phosphoric acid solution, and employing gradient elution. The characteristic spectrum constructed by the method described herein is rich in information, highly characteristic, and has good reproducibility.

The invention relates to the field of traditional Chinese medicines and discloses a traditional Chinese medicine composition for treating damp-heat downward flow type balanitis and urinary tract infection as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 8 to 12 parts of rhizoma anemarrhenae, 8 to 12 parts of cortex phellodendri, 8 to 12 parts of honeysuckle flower, 13 to 17 parts of radix scrophulariae, 8 to 12 parts of rhizoma paridis, 4 to 6 parts of radix gentianae, 4 to 6 parts of radix angelicae, 5 to 7 parts of cicada slough, 25 to 35 parts of semen coicis, 5 to 7 parts of wintersweet flower, 8 to 12 parts of cortex moutan, 13 to 17 parts of radix paeoniae rubra, 8 to 12 parts of cyrtomium rhizome, 13 to 17 parts of herba patriniae, 8 to 12 parts of radix pulsatillae and 8 to 12 parts of liquorice root. The traditional Chinese medicine composition can effectively improve symptoms such as red and swollen glans penis, astringent and painful urination and scorching urethra, remarkably improve the treatment effective rate and effectively control infection, has good safety and low cost, and is suitable for long-term or repeated attack patients to use.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine electuary for intestinal injury caused by radiotherapy and chemotherapy and a preparation method of the traditional Chinese medicine electuary. According to the composition principle of monarch, minister, assistant and guide of a traditional Chinese medicine prescription, the traditional Chinese medicine electuary is prepared by taking radix astragali preparata as a monarch drug, taking radix codonopsis and rhizoma polygonati as minister drugs, and taking poria cocos, bran-fried rhizoma atractylodis macrocephalae, hairyvein agrimony, Chinese pulsatilla root, rhizoma bletillae and pinellia ternate as assistant drugs, and taking pericarpium citri reticulatae, vinegar-processed curcuma zedoary, pseudo-ginseng and musk as assistant drugs through scientific compatibility and a preparation process. The intestinal function can be adjusted, and the intestinal injury symptom caused by radiotherapy and chemotherapy is improved.

The invention relates to application of pulsatilla saponin D in preparation of a medicine for preventing or treating human prostatic hyperplasia. The invention shows that the pulsatilla saponin D has an inhibition effect on human prostate cell WPMY-1, HPRF and BPH-1 cell strains, and can cause cell apoptosis to a certain extent, so that the pulsatilla saponin D shows the effect of preventing or treating prostatic hyperplasia.

The invention belongs to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine compound composition for treating ulcerative colitis and a preparation method thereof. Chinese pulsatilla root and coptis chinensis are used for clearing away heat and toxic materials, cooling blood and stopping dysentery; bletilla striata has the effects of astringing to stop bleeding, diminishing swelling and promoting granulation, fried sanguisorba officinalis has the effects of cooling blood, stopping bleeding, detoxifying and astringing sores, golden cypress has the effects of clearing heat and drying dampness, and ash bark has the effects of inducing astringency and stopping dysentery, all serve as ministerial drugs, assist the monarch drugs to play roles, enhance the curative effects of the monarch drugs and assist the monarch drugs in purging fire and detoxifying. The fried radix paeoniae alba is used for regulating menstruation and relieving pain, the root of Chinese toona astringents and stopping bleeding, and the radix scutellariae is used for clearing away heat and toxic materials, which are all adjuvant drugs. The liquorice serves as a conductant drug and can relieve spasm and pain and resolve the drugs. All the traditional Chinese medicine components are in synergistic interaction, so that the traditional Chinese medicine compound composition has the effects of clearing away heat and toxic materials, astringing intestines and stopping bleeding, and astringing sores and promoting tissue regeneration, and can be used for treating ulcerative colitis.

The invention relates to a fermented traditional Chinese medicine composition for preventing and treating piglet viral diarrhea as well as a preparation method and application thereof, and relates to the technical field of livestock breeding. The feed is prepared by taking traditional Chinese medicine components as basic raw materials and adding probiotics for fermentation, and the traditional Chinese medicine components comprise the following raw materials in parts by weight: 0.5-1.5 parts of cardamine violifolia dry powder, 5-15 parts of Chinese pulsatilla root, 10-20 parts of coptis chinensis, 10-20 parts of golden cypress, 10-20 parts of ash bark, 4-8 parts of turmeric, 6-10 parts of pumpkin seeds and 4-8 parts of a ginkgo leaf extract feed additive. Through cooperation of multiple components, the immunity and antioxidant functions of the body are enhanced, the structural integrity of the intestinal tract is maintained, piglet diarrhea caused by PEDV infection is effectively relieved, and growth and development of the piglet are promoted; local specialty crops are selected as medicines, and theoretical basis and practical reference are provided for deep processing of local genuine medicinal materials and PED prevention and control.

The invention relates to the technical field of preparation of feed additives, in particular to a traditional Chinese medicine compound feed additive for preventing stress syndromes of early weaned piglets and a preparation method of the traditional Chinese medicine compound feed additive. The medicine specifically comprises the following components: rhizoma osmundae, astragalus membranaceus, mangnolia officinalis, hawthorn, medicated leaven, pericarpium citri reticulatae, polygala tenuifolia, Chinese pulsatilla root, cortex fraxini, poria cocos, liquorice and spina date seed. The traditional Chinese medicine compound feed additive provided by the invention has a remarkable technical effect in the aspect of preventing the early-stage weaned piglet stress syndrome. Through scientific compatibility of various traditional Chinese medicine components, the additive can effectively improve the digestive function of the weaned piglets, enhance the immunity, relieve the stress response and remarkably reduce the diarrhea rate and the death rate. Experimental results show that piglets using the additive are superior to a blank control group and other substitution groups in the aspects of weight gain, oxidation resistance, serum hormone level, immune globulin indexes and the like, and the additive is proved to have a comprehensive physiological regulation function.

The application discloses a medicine composition for treating infant night cough, which is composed of Radix Bupleuri, Radix Paeoniae Alba, Fructus Aurantii Immaturus, roasted Germinated Millet, roasted Millet, Pericarpium Citri Reticulatae, Folium Pyrrosiae, Radix Trichosanthis, Radix Pulsatillae, Radix Anemarrhenae, Radix Peucedani, Radix Trichosanthis, Radix Ophiopogonis, Radix Sophorae Immaturus, and Radix Glycyrrhizae. The medicine composition can be added with pharmaceutically acceptable adjuvants to form preparations. The medicine composition and the preparations can be used for preparing medicines for treating infant night cough.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating radiation proctitis and a preparation method thereof.The traditional Chinese medicine composition is prepared from rhizoma coptidis processed with wine, radix scutellariae slices, radix rehmanniae recen, baked ginger, rhizoma atractylodis macrocephalae fried with bran, carbonized sanguisorba root, the root of Chinese pulsatilla, rhizoma bletillae, the root of kudzu vine, astragalus membranaceus, carbonized hair, honey-fried licorice root, radix paeoniae alba and rhizoma nelumbinis charcoal. According to the principle of clearing heat, promoting diuresis, detoxifying, cooling blood, dispersing blood stasis and stopping bleeding in traditional Chinese medicine, the pathological states of internal exuberance of fire-heat toxins and burns intestinal collaterals are comprehensively conditioned. Clinical research proves that the medicine can improve the traditional Chinese medicine syndrome score of patients suffering from stomachache, diarrhea, mucous bloody stool type rectum mucosa edema, hyperemia, bleeding and even ulceration and ulceration caused by radiotherapy, has practical popularization and application value, and is worthy of popularization and application. Therefore, the problems that the existing western medicine for treating radiation proctitis can only temporarily relieve symptoms, cannot repair intestinal mucosa injury and is easy to cause drug resistance and intestinal flora imbalance are solved.

The application relates to the technical field of traditional Chinese medicine preparation, and particularly discloses a compound traditional Chinese medicine preparation for targeting egg duck and goose egg cytoplasmic disease, which comprises the following components: white head, Coptis chinensis, Huangqi, Phellodendron amurense, wine Danpi, bran-fried peach kernel, Chinese perilla, pomegranate peel, liquorice, honeysuckle, Andrographis, figwort, emblic, ginger, fried atractylodes, fried safflower, Xianhecao, spiny amaranth, and Poria cocos. Through the combination of monarch, minister, assistant and messenger, the core effects of heat-clearing and detoxifying, blood-cooling and dysentery-stopping, and dampness-drying and insect-killing of the medicines are synergistically exerted, the pathogenesis characteristics of the egg cytoplasmic disease are accurately targeted, blood stasis and blood circulation are promoted to eliminate the swelling of the lesion, and the intestinal mucosa damage is repaired to stop bleeding, the symptoms of hematochezia, diarrhea and oviduct inflammation of the egg duck and goose caused by the egg cytoplasmic disease are effectively relieved, the problems of the decreased antibiotic effect, drug residue, bacterial flora disorder and food safety risk are effectively solved, and the compound traditional Chinese medicine preparation has the remarkable progress of drug resistance, safety, no residue, intestinal protection and green environmental protection.

The invention discloses an anti-tumor traditional Chinese medicine compound capable of removing three flavors. The anti-tumor traditional Chinese medicine compound is prepared from radix puerariae, radix scutellariae, rhizoma coptidis, cortex phellodendri, rhizoma atractylodis, radix angelicae sinensis, radix aucklandiae, radix pulsatillae, herba hedyotidis diffusae, rhizoma atractylodis macrocephalae and raw liquorice Compared with the original formula of compound radix puerariae decoction, the three-component-removing anti-tumor traditional Chinese medicine compound has the advantages that the three traditional Chinese medicines of gentiana macrophylla, rhizoma alismatis and betel nut which do not have the effects of clearing away heat and toxic materials and tonifying spleen and do not enter lung meridians are removed, the three-component-removing anti-tumor traditional Chinese medicine compound is obtained, and research finds that the formula still has the anti-colorectal cancer efficacy, the anti-breast cancer efficacy is increased, and the anti-tumor effect is good. Compared with the original formula of the compound radix puerariae decoction, the compound radix puerariae decoction has higher safety.

The invention discloses a traditional Chinese medicine composition for treating constipation as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The composition comprises the following components in parts by weight: 45 to 85 parts of Chinese pulsatilla root, 45 to 85 parts of oldenlandia diffusa, 45 to 85 parts of sculellaria barbata, 80 to 140 parts of Chinese actinidia root, 45 to 85 parts of trogopterus dung, 80 to 140 parts of coix seed, 80 to 140 parts of poria cocos, 80 to 140 parts of rhizoma pinellinae praeparata, 45 to 85 parts of pericarpium citri reticulatae, 60 to 100 parts of bighead atractylodes rhizome, 45 to 85 parts of endothelium corneum gigeriae galli, 60 to 100 parts of white hyacinth bean, 60 to 100 parts of dried ginger and 45 to 85 parts of liquorice. The traditional Chinese medicine composition has a good treatment effect on constipation caused by gastrointestinal tumors, is mild in medicine property, and is specially developed for patients with constipation caused by tumors.

The invention belongs to the technical field of medicines, discloses a synergistic pharmaceutical composition based on pulsatilla saponin and bifendate and application of the synergistic pharmaceutical composition in treatment of acute liver injury, and particularly discloses a pharmaceutical composition which comprises pulsatilla saponin B4 and bifendate or dexamethasone. The invention provides a pharmaceutical composition containing pulsatilla saponin B4 (BS-B4) and a drug bifendate or dexamethasone combined with the pulsatilla saponin B4, and experiments prove that the pharmaceutical composition has good effects of preventing and treating acute liver injury and can effectively reduce spleen and liver indexes and expression of serum liver injury markers (ALT, AST and T-Bil-V). The pharmaceutical composition can be used for effectively relieving acute liver injury induced by carbon tetrachloride by regulating inflammatory factors (IL-1beta, TNF-alpha and IL-10) and oxidative stress pathways (MDA and GSH-Px).

The invention provides a Chinese pulsatilla root oral liquid preparation and a preparation method thereof.The Chinese pulsatilla root oral liquid preparation per liter comprises 300 g of Chinese pulsatilla roots, 150 g of rhizoma coptidis, 300 g of cortex fraxini, 225 g of cortex phellodendri, 50 ml of PEG-400, 20 g of xanthan gum, 20 g of hydrophilic colloidal silicon dioxide, 5 g of neotame, 1.5 g of ethylparaben and the balance auxiliary materials. The palatability is better, and the clinical effect is obviously improved compared with that of other similar products.

The invention discloses an anemoside B4 derivative as well as a preparation method and application thereof, a compound anemoside B4 (abbreviated as B4 or AB4) is taken as a raw material, and the derivative is prepared by respectively carrying out nucleophilic substitution, electrophilic addition, esterification reaction or amidation and other reactions on C-19 exocyclic double bonds or C-28 carboxyl. The compound is used as an active component to prepare medicines with anti-inflammatory and immunoregulation effects. The invention discloses the effect of the B4 derivative on treating inflammatory diseases such as inflammatory bowel disease, atopic dermatitis, eczema and psoriasis for the first time, and the drug effect of the B4 derivative is superior to that of B4 or clinically common drugs. In addition, the invention also discloses that most B4 derivatives do not show obvious cytotoxicity to macrophages for the first time, can reduce the P-I kappa Ba protein level in LPS and ATP induced macrophage NF-kappa B signaling pathways, inhibit the activation of NLRP3 signaling pathways and obviously reduce the Pro-IL-1beta level (p is less than 0.05), namely inhibit the activation of inflammasome pathways, and the effect is superior to that of B4; the results show that the B4 derivative disclosed by the invention has better anti-inflammatory activity.

The application discloses a traditional Chinese medicine composition for treating lung cancer and a preparation method thereof. The traditional Chinese medicine composition comprises the following raw medicinal materials in parts by weight: Platycladi seeds 5-8 parts, Aescleris stems 19-22 parts, Persicae Nucis 12-15 parts, Radix Pulsatillae 5-8 parts, Coicis Semen 35-38 parts, Benincasae Semen 12-15 parts, Herba Gnaphalii 12-15 parts, Baeckea frutescens 12-15 parts, Citri Reticulatae Pericarpium 5-8 parts and Fructus Jujubae 5-8 parts. The traditional Chinese medicine composition is developed on the basis of the pathogenesis of phlegm and blood stasis of lung cancer in traditional Chinese medicine, combined with classical prescriptions for treating lung diseases in traditional Chinese medicine and laboratory anti-lung cancer drug screening research, and has the effect of inhibiting lung cancer cell growth and good effect on the treatment of lung cancer. Experiments prove that the traditional Chinese medicine composition significantly inhibits lung cancer cell proliferation in vitro and improves the lung cancer pathological process of lung cancer mice in vivo, and is a great innovation of lung cancer drugs.

The invention discloses a laying hen feed and a preparation method thereof, and aims to improve the production performance, intestinal health, feed conversion rate and eggshell quality of laying hens. The feed is prepared from conventional raw materials such as corn, soybean meal, fish meal and the like, Chinese herbal compounds such as Chinese pulsatilla roots, radix scutellariae, berberine and the like, and functional additives such as cello-oligosaccharide, gamma-aminobutyric acid, medical stone and the like. Through the synergistic effect of the traditional Chinese medicine compound and the functional additive, a multi-dimensional intestinal tract protection barrier is constructed; a graded crushing and premixing process is adopted, so that accurate release of nutrients is realized, and the feed conversion rate is increased; chinese herbal compound compatibility activates the production performance of laying hens and improves the laying rate; the composite application of medical stone and zeolite is utilized to optimize the gradient adsorption and slow release of mineral elements. The laying hen feed disclosed by the invention has remarkable effects in the aspects of reducing enteritis morbidity, improving production performance, optimizing feed utilization and eggshell quality and the like, and has a wide application prospect.

The invention relates to a fermented Chinese pulsatilla root preparation for improving the yield of laying hens in humid and hot weather, relieving stress and improving the antioxidant function. Specifically, the invention provides application of the traditional Chinese medicine fermentation composition, and the traditional Chinese medicine fermentation composition is applied to one or more of the following groups: the traditional Chinese medicine fermentation composition is used for improving the feed conversion rate of poultry; the morbidity and mortality of poultry are reduced; the composition is used for reducing the hormone level related to high-temperature and high-humidity stress of poultry; the preparation method of the fermented Chinese pulsatilla root composition comprises the following steps: carrying out expanding culture on bacillus subtilis, lactobacillus plantarum and candida utilis to obtain compound probiotic liquid, and fermenting Chinese pulsatilla root powder by using the compound probiotic liquid to obtain the fermented composition. The feed has the advantages of solving the prominent problems of reduced immunity, high incidence of pathogenic bacteria infection, reduced production performance and the like caused by environmental stress in laying hen breeding in southern hot and humid areas, so as to improve the economic value of poultry production in summer.

The present invention relates to the field of biomedicine and provides the use of a STAT3 dual-phosphorylation inhibitor in the preparation of a drug for preventing or treating triple-negative breast cancer. The STAT3 dual-phosphorylation inhibitor comprises pulsatilla saponin E2 and / or a pharmaceutically acceptable salt thereof. As a STAT3 dual-phosphorylation inhibitor, pulsatilla saponin E2 can effectively inhibit the growth and migration of triple-negative breast cancer cells. Its application in the treatment of triple-negative breast cancer has the advantages of good efficacy and minimal toxic side effects.

The application belongs to the technical field of biological medicine, and particularly relates to a Pulsatillae radix vesicle, a preparation method thereof and application thereof in intestinal inflammation. The preparation method comprises the following steps: crushing fresh Pulsatillae radix, squeezing juice, filtering, and collecting the filtrate; centrifuging the filtrate at low speed, collecting the supernatant; and finally centrifuging the supernatant, collecting the precipitate, suspending the precipitate in PBS, and drying, to obtain the Pulsatillae radix vesicle. The Pulsatillae radix vesicle prepared by the method has a small particle size, is a nanometer carrier, carries rich active substances such as lipids and proteins, has natural targeting to the pathological site through multi-component synergistic effect, has high safety, low immunogenicity, and no ethical controversy.

The invention provides a traditional Chinese medicine enema for treating radiation enteritis, and belongs to the technical field of biological medicines. According to the technical scheme, a simplified formula and a complete formula are included, the complete formula comprises 12 components including radix scutellariae, rhizoma coptidis, the root of Chinese pulsatilla, the bark of ash, raw radix sanguisorbae, herba patriniae, vinegar-processed rhizoma corydalis, radix puerariae thomsonii, cortex phellodendri, oldenlandia diffusa, dandelion and the root of three-nerved spicebush, and according to the simplified formula, the cortex phellodendri, the oldenlandia diffusa, the dandelion and the root of three-nerved spicebush are removed on the basis of the complete formula. Compared with a complete formula, the simple formula provided by the invention has the advantages that the medicine flavor is reduced from 12 to 8, and potential medicine interaction and intestinal irritation are reduced. The Chinese pulsatilla root decoction is based on Chinese pulsatilla root decoction, the raw sanguisorba root and the patrinia herb are supplemented to enhance mucous membrane repair, the corydalis tuber relieves pain, the pachyrhizua angulatus improves diarrhea, and effective improvement of a classic formula is achieved. The traditional Chinese medicine composition has the effects of clearing heat, drying dampness, cooling blood, detoxifying, promoting qi circulation, relieving pain, raising yang and stopping diarrhea, has the effects of clearing heat, cooling blood, stopping bleeding, relieving pain and the like, and has an exact and remarkable treatment effect on radiation enteritis.

The invention relates to the technical field of feed additives, in particular to a feed additive for preventing and treating diarrhea of livestock and poultry as well as a preparation method and application of the feed additive. The feed additive comprises 10-30 parts of traditional Chinese medicine dry paste powder and 70-90 parts of auxiliary materials, wherein the traditional Chinese medicine dry paste powder comprises a traditional Chinese medicine extract extracted from the following traditional Chinese medicine compositions in parts by weight: 5-15 parts of coptis chinensis, 8-15 parts of Chinese pulsatilla root, 3-8 parts of carbonized sanguisorba root, 5-12 parts of honeysuckle stem, 2-5 parts of corydalis tuber, 3-6 parts of elecampane, 5-10 parts of ash bark, 8-15 parts of humifuse euphorbia herb, 8-15 parts of Chinese yam, 8-15 parts of white hyacinth bean, 3-6 parts of fingered citron, 3-6 parts of fortune eupatorium herb and 3-6 parts of raw liquorice. According to the invention, the unique compatibility theory of traditional Chinese medicines is utilized to form a multi-component synergistic effect, pathogens are not easy to generate drug resistance, the residue is low, the safety is high, the requirements of current mainstream'antibiotic-free breeding 'can be met, diarrhea is prevented and treated through the multi-dimensional effects of checking diarrhea, regulating bacteria, protecting membranes, resisting inflammation and promoting digestion, and the feed has the dual advantages of disease prevention and treatment and green safety.

The invention discloses a preparation method of colon powder for external use, and relates to the technical field of medicine preparation. The colon powder for external use is prepared from the following raw materials in parts by weight: 15 to 25 parts of radix astragali seu hedysari, 10 to 20 parts of radix pulsatillae, 8 to 18 parts of radix astragali seu hedysari, 6 to 16 parts of radix arnebiae seu lithospermi and 3 to 8 parts of auxiliary materials. The preparation method comprises the steps of raw material pretreatment, extraction, drying, mixing and sterilization. The raw materials also comprise the following components in parts by weight: 5-15 parts of purslane and 4-12 parts of cortex fraxini, and the weight ratio of the purslane to the cortex fraxini is 1: (0.8-1.2). According to the present invention, the radix astragali seu hedysari, the Chinese pulsatilla root, the radix astragali seu hedysari and the laver are adopted as the raw materials, the radix astragali seu hedysari has effects of spleen strengthening and qi supplementing, the Chinese pulsatilla root has effects of heat clearing and detoxification, the radix astragali seu hedysari has effects of immunity enhancing, and the radix arnebiae seu lithospermi has effects of blood cooling and blood activating so as to achieve multiple effects of inflammation resistance, colonic the treatment of ulcerative colitis and other diseases is remarkably improved, and the problems that an existing formula is single and the curative effect is limited are solved.

The invention relates to the technical field of traditional Chinese medicine preparations, and particularly discloses a traditional Chinese medicine composition capable of preventing and treating duck plague, a traditional Chinese medicine preparation and a preparation method and application thereof. The traditional Chinese medicine composition capable of preventing and treating duck disease comprises the following raw material components in parts by mass: 5-15 parts of corydalis conspersa, 5-15 parts of garlic, 15-25 parts of wild buckwheat rhizome, 5-10 parts of Chinese pulsatilla root, 5-10 parts of dandelion, 5-10 parts of scutellaria baicalensis, 5-10 parts of fructus forsythiae, 1-5 parts of humifuse euphorbia herb and 1-5 parts of liquorice. The traditional Chinese medicine preparation is prepared by taking the traditional Chinese medicine composition and polysaccharide as main raw materials, the traditional Chinese medicine preparation can be used for rapidly and effectively preventing and treating the duck plague, the preparation method is simple and convenient, the cost is low, and the defects in the prior art are overcome.

The invention discloses a traditional Chinese medicine formula for preventing and treating diabetic foot. The traditional Chinese medicine formula is prepared from deer root, perillaseed, coix seed, motherwort, herba siegesbeckiae, turmeric, mango leaf, sappan wood, kudzuvine root, nettle, Chinese pulsatilla root, rhizoma dioscoreae nipponicae, centipede and leech. The traditional Chinese medicine composition has the advantages that the medicines are combined, the pathological links of promoting blood circulation to remove meridian obstruction, resisting inflammation and detoxifying, promoting repair, conditioning the whole body and acting on the diabetic foot at multiple targets are realized, the symptoms such as foot pain, swelling and numbness are relieved, the ulcer healing is promoted, the treatment effect is good, the side effect is small, the treatment period is short, and the life quality of patients can be effectively improved.

The invention relates to the field of feed additives, and aims to provide a traditional Chinese medicine feed additive for preventing respiratory diseases of piglets and application of the traditional Chinese medicine feed additive. The additive takes scutellaria baicalensis and honeysuckle as monarch drugs, pulsatilla chinensis as a ministerial drug, and bighead atractylodes rhizome, radix paeoniae alba, elecampane and pericarpium citri reticulatae as adjuvant drugs; the traditional Chinese medicine composition is specifically prepared from the following raw materials in parts by weight: 170 to 190 parts of radix scutellariae, 170 to 190 parts of flos lonicerae, 140 to 160 parts of radix pulsatillae, 140 to 160 parts of rhizoma atractylodis macrocephalae, 110 to 130 parts of radix paeoniae alba, 110 to 130 parts of radix aucklandiae and 90 to 110 parts of pericarpium citri reticulatae. According to the invention, a compatibility strategy of eliminating evil, strengthening body resistance and treating qi, blood and phlegm is creatively adopted, and a multi-target synergistic effect is adopted to realize the purpose of preventing the respiratory diseases of the piglets, so that the limitation of simply treating the respiratory diseases is broken through. The traditional Chinese medicine composition can improve the structure of respiratory flora of piglets, reduce the abundance of harmful bacteria and enhance the immunity of the organism, so that the occurrence probability of respiratory diseases is effectively reduced.

The invention relates to the technical field of feed additives, in particular to a traditional Chinese medicine composition for preventing and treating streptococcus iniae diseases of humpback perches as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by weight: 10-15 parts of eucommia ulmoides, 10-15 parts of folium artemisiae argyi, 10 parts of radix angelicae, 10-13 parts of rhizoma zingiberis, 10-12 parts of liquorice, 7-9 parts of caulis spatholobi, 7-8 parts of herba ecliptae, 7-8 parts of radix ophiopogonis, 6-7 parts of poria cocos, 7-8 parts of hawthorn, 3-5 parts of radix aucklandiae, 3-4 parts of dendrobe, 3-5 parts of radix pulsatillae and 3-5 parts of radix puerariae. By feeding the traditional Chinese medicine composition provided by the invention, the weight gain rate of the humpback perches is increased by 20%, and the death rate of the humpback perches infected with streptococcus iniae is reduced by 10%.

The application provides a traditional Chinese medicine composition for treating avian colibacillosis and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations.The preparation method is as follows: 12-15 parts of Huangqin, 9-11 parts of Huanglian, 3.5-4.5 parts of Jinyinhua, 5-7 parts of Chuanxinlian and 5-7 parts of Pugongying are mixed, crushed, 8-10 times of the mass of an acidic ethanol solution is added, extracted, filtered, and a composite liquid one is obtained; 11-13 parts of Gegen, 10-12 parts of Baotouweng, 4-5 parts of Cebaiye, 6-7 parts of Wuhezi and 7-9 parts of Zixingujia are mixed, crushed, 8-10 times of the mass of an ethanol aqueous solution is added, extracted, filtered, and a composite liquid two is obtained; the composite liquid one and the composite liquid two are respectively vacuum rotary evaporated to a relative density of 1.09-1.13, mixed, and spray dried, and the traditional Chinese medicine composition is obtained.The traditional Chinese medicine composition prepared by the application has a fast effect speed and a remarkable curative effect for treating avian colibacillosis of chicks.

1. The name of the design product: packaging box (Tianjia Dizhang Houshen Dianfang Pulsatillae Poria Polypeptide Powder). 2. The use of the design product: for Tianjia Dizhang Houshen Dianfang Pulsatillae Poria Polypeptide Powder product packaging. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective drawing.

The invention discloses a high-immunity polypeptide biological preparation containing cornu cervi pantotrichum and a preparation method of the high-immunity polypeptide biological preparation, and belongs to the technical field of biological preparations. The high-immunity polypeptide biological preparation is prepared from the following components in parts by weight: 10 to 15 parts of sika deer cornu cervi pantotrichum, 3 to 4 parts of methoxy polyethylene glycol succinimidyl propionate, 20 to 25 parts of radix pulsatillae, 18 to 22 parts of rhizoma polygoni cuspidati, 8 to 10 parts of radix ginseng, 22 to 26 parts of radix glycyrrhizae and 30 to 40 parts of distilled water. The pilose antler polypeptide is subjected to terminal modification through methoxyl polyethylene glycol propionate succinimide ester, the water solubility of the pilose antler polypeptide is improved, the absorption rate of the pilose antler polypeptide is improved, the technical effect of improving the bioavailability is achieved, meanwhile, the pilose antler polypeptide and the traditional Chinese medicine extract are jointly used for preparing the nano-emulsion, the preservation time of the preparation is prolonged, and the safety of the preparation is improved.