Traditional Chinese medicine compound feed additive for preventing stress syndrome of early weaned piglets and preparation method of traditional Chinese medicine compound feed additive

Traditional Chinese medicine compound feed additives, formulated with scientific compatibility and modern preparation technology, have solved the problem of early weaning stress syndrome in piglets, achieving improved digestive function, enhanced immunity, and improved growth performance, thus meeting the requirements of green and environmentally friendly breeding.

CN120982647APending Publication Date: 2025-11-21SHANXI AGRI UNIV
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Patent Information

Application Number
CN202511445556.6
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-10-10
Publication Date
2025-11-21

AI Technical Summary

Technical Problem

In existing technologies, early weaning causes stress syndromes in piglets, such as digestive dysfunction, immunosuppression, and abnormal behavior. Furthermore, preventive antibiotic interventions can lead to problems such as heavy metal accumulation, spread of microbial resistance, and intestinal flora imbalance. There is a lack of green alternative products.

Method used

This compound feed additive is prepared by using a combination of traditional Chinese medicines such as Os scutellaria baicalensis, Astragalus membranaceus, Magnolia officinalis, Crataegus pinnatifida, Medicated leaven, Citrus reticulata peel, Polygala tenuifolia, Pulsatilla chinensis, Fraxinus chinensis, Poria cocos, Glycyrrhiza uralensis, and Ziziphus jujuba var. spinosa. It is prepared through precise pulverization, water decoction concentration, and low-temperature drying. It is designed to specifically improve digestive function, enhance immunity, and resist stress response.

Benefits of technology

It significantly reduces the diarrhea and mortality rates of weaned piglets, improves growth performance, enhances immune function, improves sleep quality, and increases bioavailability, aligning with the trend of green and environmentally friendly farming and improving farming efficiency.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of preparation of feed additives, in particular to a traditional Chinese medicine compound feed additive for preventing stress syndromes of early weaned piglets and a preparation method of the traditional Chinese medicine compound feed additive. The medicine specifically comprises the following components: rhizoma osmundae, astragalus membranaceus, mangnolia officinalis, hawthorn, medicated leaven, pericarpium citri reticulatae, polygala tenuifolia, Chinese pulsatilla root, cortex fraxini, poria cocos, liquorice and spina date seed. The traditional Chinese medicine compound feed additive provided by the invention has a remarkable technical effect in the aspect of preventing the early-stage weaned piglet stress syndrome. Through scientific compatibility of various traditional Chinese medicine components, the additive can effectively improve the digestive function of the weaned piglets, enhance the immunity, relieve the stress response and remarkably reduce the diarrhea rate and the death rate. Experimental results show that piglets using the additive are superior to a blank control group and other substitution groups in the aspects of weight gain, oxidation resistance, serum hormone level, immune globulin indexes and the like, and the additive is proved to have a comprehensive physiological regulation function.
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Description

Technical Field

[0001] This invention relates to the field of feed additive preparation technology, and in particular to a traditional Chinese medicine compound feed additive for preventing early weaning stress syndrome in piglets and its preparation method. Background Technology

[0002] Early weaning, as a core management technique in modern intensive pig farming, has significantly improved sow productivity, but it inevitably poses severe challenges to the physiological functions of piglets. During the weaning stage, piglets face multiple stressors, including sudden changes in nutritional sources, environmental adaptation stress, and the loss of maternal antibodies, often leading to stress syndromes characterized by digestive dysfunction, immunosuppression, and abnormal behavior. These symptoms not only directly restrict the growth performance and health of piglets but are also significant contributing factors to decreased economic benefits in pig farms and the overuse of antibiotics.

[0003] Currently, the industry commonly uses antibiotic combinations for preventative intervention. While these can control diarrhea and secondary infections in the short term, long-term use can easily lead to secondary harms such as heavy metal accumulation, the spread of antimicrobial resistance, and intestinal flora imbalance. With the continued advancement of global "antibiotic reduction" policies, developing green alternative products that combine nutritional regulation and pathological prevention has become a research focus in the field of animal nutrition.

[0004] Traditional Chinese medicine (TCM) compound formulas, with their holistic regulation and multi-target intervention characteristics, demonstrate unique advantages in alleviating animal stress responses. However, existing technologies have several limitations: on the one hand, most compound formula designs remain at the stage of traditional empirical combinations, failing to fully integrate with modern animal physiology and stress pathology mechanisms; on the other hand, conventional pulverization and addition methods result in low bioavailability, and bitter substances affect feed intake. There is an urgent need to develop a novel TCM feed additive that can effectively integrate growth-promoting, stress-resistant, and immune-regulating functions through scientific formulation optimization and innovative preparation processes. Summary of the Invention

[0005] The purpose of this invention is to provide a traditional Chinese medicine compound feed additive for preventing early weaning stress syndrome in piglets and its preparation method.

[0006] To achieve the above-mentioned objectives, the present invention provides the following technical solution: This invention provides a traditional Chinese medicine compound feed additive for preventing early weaning stress syndrome in piglets, comprising the following components in parts by weight: 10-15 parts of Osmanthus fragrans, 10-15 parts of Astragalus membranaceus, 15-20 parts of Magnolia officinalis, 20-30 parts of Crataegus pinnatifida, 15-25 parts of Massa fermentata, 15-20 parts of Citrus reticulata peel, 10-15 parts of Polygala tenuifolia, 10-15 parts of Pulsatilla chinensis, 8-12 parts of Fraxinus chinensis, 15-20 parts of Poria cocos, 5-10 parts of Glycyrrhiza uralensis, and 10-15 parts of Ziziphus jujuba var. spinosa.

[0007] This invention also provides a method for preparing the aforementioned traditional Chinese medicine compound feed additive, comprising the following steps: (1) Mix and grind the following ingredients together: Os scutellaria, Astragalus membranaceus, Magnolia officinalis, Crataegus pinnatifida, Medicated leaven, Citrus reticulata peel, Polygala tenuifolia, Pulsatilla chinensis, Fraxinus chinensis, Poria cocos, Glycyrrhiza uralensis and Ziziphus jujuba var. spinosa to obtain material 1; (2) Mix the material 1 with water and boil to obtain a filtrate; (3) The filtrate is concentrated under reduced pressure to obtain an extract, which is then dried to obtain the final product.

[0008] Preferably, the material after grinding in step (1) is passed through a 55-75 mesh sieve, and the material under the sieve is material 1.

[0009] Preferably, the mass ratio of material 1 to water in step (2) is 1:4~7.

[0010] Preferably, the simmering time in step (2) is 2 to 4 hours.

[0011] Preferably, the extract obtained by step (3) is concentrated under reduced pressure to a relative density of 1.12 to 1.20 at 65°C.

[0012] Preferably, the drying temperature in step (3) is 75~85℃.

[0013] Preferably, the drying time in step (4) is 2 to 4 hours.

[0014] This invention also provides the application of the aforementioned traditional Chinese medicine compound feed additive in the preparation of weaned piglet feed.

[0015] Preferably, the mass ratio of the traditional Chinese medicine compound feed additive in the weaned piglet feed is 1.5 to 3.5%.

[0016] Compared with the prior art, the present invention has the following beneficial effects: In this compound formula, hawthorn and medicated leaven work synergistically to invigorate the stomach and promote digestion, addressing the core issue of insufficient digestive function in piglets by powerfully promoting digestion and preventing nutritional diarrhea caused by indigestion. The assistant herbs include tangerine peel and magnolia bark to regulate qi and relieve bloating; astragalus to tonify qi and raise yang, enhancing the body's disease resistance; and poria to invigorate the spleen and eliminate dampness, while also calming the mind. These herbs work synergistically with the principal herbs to enhance the therapeutic effect from the perspectives of spleen and stomach qi and overall health.

[0017] The adjuvant herbs are divided into two aspects: First, Ziziphus jujuba seed and Polygala tenuifolia are specifically used for anti-stress and calming the nerves, directly regulating the function of the nervous system, reducing abnormal behaviors such as restlessness, screaming, and tail biting caused by weaning stress, and improving sleep quality; Second, Os scutellaria baicalensis, Dryopteris crassirhizoma, Pulsatilla chinensis, and Fraxinus chinensis are used as heat-clearing and disease-preventing herbs to eliminate potential damp-heat pathogens, inhibit the proliferation of harmful bacteria in the intestines, and prevent secondary infections. The guiding herb, Glycyrrhiza uralensis, harmonizes the properties of all the herbs while improving palatability, ensuring the overall coordination of the preparation and feeding acceptance.

[0018] The traditional Chinese medicine compound feed additive provided by this invention has shown significant technical effects in preventing early weaning stress syndrome in piglets. Through the scientific formulation of various traditional Chinese medicine ingredients, this additive can effectively improve the digestive function of weaned piglets, enhance immunity, alleviate stress responses, and significantly reduce diarrhea and mortality rates. Experimental results show that piglets using this additive are superior to the blank control group and other alternative groups in terms of weight gain, antioxidant capacity, serum hormone levels, and immunoglobulin indicators, confirming its comprehensive physiological regulatory function.

[0019] Furthermore, this additive employs modern preparation processes, such as precision pulverization, water decoction concentration, and low-temperature drying, effectively improving the dissolution rate and bioavailability of active ingredients. This avoids the problems of poor palatability and low absorption rates caused by traditional pulverization methods. This product aligns with the industry trend of "antibiotic reduction" and has promising prospects for widespread application. It can serve as a green and safe feed additive to replace antibiotics, improving breeding efficiency and animal welfare. Detailed Implementation

[0020] This invention provides a traditional Chinese medicine compound feed additive for preventing early weaning stress syndrome in piglets, characterized by comprising the following components in parts by weight: 10-15 parts of Osmanthus fragrans, 10-15 parts of Astragalus membranaceus, 15-20 parts of Magnolia officinalis, 20-30 parts of Crataegus pinnatifida, 15-25 parts of Massa fermentata, 15-20 parts of Citrus reticulata peel, 10-15 parts of Polygala tenuifolia, 10-15 parts of Pulsatilla chinensis, 8-12 parts of Fraxinus chinensis, 15-20 parts of Poria cocos, 5-10 parts of Glycyrrhiza uralensis, and 10-15 parts of Ziziphus jujuba var. spinosa. The preferred ingredients are: 11-14 parts of Ostreae and Dryopteris crassirhizoma, 11-14 parts of Astragalus membranaceus, 16-19 parts of Magnolia officinalis, 22-28 parts of Crataegus pinnatifida, 17-23 parts of Massa fermentata, 16-19 parts of Citrus reticulata peel, 11-14 parts of Polygala tenuifolia, 11-14 parts of Pulsatilla chinensis, 9-11 parts of Fraxinus chinensis, 16-19 parts of Poria cocos, 6-9 parts of Glycyrrhiza uralensis, and 11-14 parts of Ziziphus jujuba var. spinosa. Further preferred ingredients include 12-13 parts of Ostridium perfringens and Dryopteris crassirhizoma, 12-13 parts of Astragalus membranaceus, 17-18 parts of Magnolia officinalis, 24-26 parts of Crataegus pinnatifida, 19-21 parts of Massa fermentata, 17-18 parts of Citrus reticulata peel, 12-13 parts of Polygala tenuifolia, 12-13 parts of Pulsatilla chinensis, 9-11 parts of Fraxinus chinensis, 17-18 parts of Poria cocos, 7-8 parts of Glycyrrhiza uralensis, and 12-13 parts of Ziziphus jujuba var. spinosa. More preferably, it consists of 13 parts of *Dryopteris crassirhizoma*, 13 parts of *Astragalus membranaceus*, 18 parts of *Magnolia officinalis*, 25 parts of hawthorn, 20 parts of *Medicated Leaven*, 18 parts of dried tangerine peel, 13 parts of *Polygala tenuifolia*, 13 parts of *Pulsatilla chinensis*, 10 parts of *Fraxinus chinensis*, 18 parts of *Poria cocos*, 8 parts of licorice, and 13 parts of *Ziziphus jujuba* seed.

[0021] This invention also provides a method for preparing the aforementioned traditional Chinese medicine compound feed additive, comprising the following steps: (1) Mix and grind the following ingredients together: Os scutellaria, Astragalus membranaceus, Magnolia officinalis, Crataegus pinnatifida, Medicated leaven, Citrus reticulata peel, Polygala tenuifolia, Pulsatilla chinensis, Fraxinus chinensis, Poria cocos, Glycyrrhiza uralensis and Ziziphus jujuba var. spinosa to obtain material 1; (2) Mix the material 1 with water and boil to obtain a filtrate; (3) The filtrate is concentrated under reduced pressure to obtain an extract, which is then dried to obtain the final product.

[0022] In this invention, the ground material in step (1) is passed through a 55-75 mesh sieve, and the material collected under the sieve is material 1; preferably 60-70 mesh; more preferably 65 mesh.

[0023] In this invention, the mass ratio of material 1 to water in step (2) is 1:4~7; preferably 1:5~6; and more preferably 1:6.

[0024] In this invention, the simmering time in step (2) is 2 to 4 hours; preferably 3 hours.

[0025] In this invention, the extract concentrated under reduced pressure to 65°C in step (3) has a relative density of 1.12 to 1.20; preferably 1.14 to 1.18; more preferably 1.15 to 1.17; and more preferably 1.16.

[0026] In this invention, the drying temperature in step (3) is 75~85℃; preferably 77~83℃; more preferably 79~81℃; and even more preferably 80℃.

[0027] In this invention, the drying time in step (4) is 2 to 4 hours; preferably 3 hours.

[0028] This invention also provides the application of the aforementioned traditional Chinese medicine compound feed additive in the preparation of weaned piglet feed.

[0029] In this invention, the mass ratio of the traditional Chinese medicine compound feed additive in the weaned piglet feed is 1.5-3.5%; preferably 1.5%.

[0030] The technical solutions provided by the present invention will be described in detail below with reference to the embodiments, but they should not be construed as limiting the scope of protection of the present invention.

[0031] Example 1

[0032] A traditional Chinese medicine compound feed additive for preventing early weaning stress syndrome in piglets, comprising the following components in parts by weight: 15 parts of Osmanthus fragrans, 10 parts of Astragalus membranaceus, 15 parts of Magnolia officinalis, 20 parts of Crataegus pinnatifida, 15 parts of Massa fermentata, 15 parts of Citrus reticulata peel, 10 parts of Polygala tenuifolia, 10 parts of Pulsatilla chinensis, 12 parts of Fraxinus chinensis, 15 parts of Poria cocos, 5 parts of Glycyrrhiza uralensis, and 10 parts of Ziziphus jujuba var. spinosa. The preparation method of the aforementioned traditional Chinese medicine compound feed additive includes the following steps: (1) Mix and grind the following ingredients: Osmanthus fragrans, Astragalus membranaceus, Magnolia officinalis, Crataegus pinnatifida, Medicated leaven, Citrus reticulata peel, Polygala tenuifolia, Pulsatilla chinensis, Fraxinus chinensis, Poria cocos, Glycyrrhiza uralensis and Ziziphus jujuba var. spinosa. After grinding, pass the material through a 55-mesh sieve and collect the material that passes through the sieve as material 1. (2) Mix the material 1 with water at a mass ratio of 1:4 and boil for 2 hours to obtain the filtrate; (3) The filtrate is concentrated under reduced pressure to an extract with a relative density of 1.12 at 65°C, and then dried at 75°C for 2 hours to obtain the final product.

[0033] Example 2

[0034] A traditional Chinese medicine compound feed additive for preventing early weaning stress syndrome in piglets, comprising the following components in parts by weight: 10 parts of Osmanthus fragrans, 15 parts of Astragalus membranaceus, 20 parts of Magnolia officinalis, 30 parts of Crataegus pinnatifida, 25 parts of Massa fermentata, 20 parts of Citrus reticulata peel, 15 parts of Polygala tenuifolia, 15 parts of Pulsatilla chinensis, 12 parts of Fraxinus chinensis, 20 parts of Poria cocos, 10 parts of Glycyrrhiza uralensis, and 15 parts of Ziziphus jujuba var. spinosa. The preparation method of the aforementioned traditional Chinese medicine compound feed additive includes the following steps: (1) Mix and grind the following ingredients: Osmanthus fragrans, Astragalus membranaceus, Magnolia officinalis, Crataegus pinnatifida, Medicated leaven, Citrus reticulata peel, Polygala tenuifolia, Pulsatilla chinensis, Fraxinus chinensis, Poria cocos, Glycyrrhiza uralensis and Ziziphus jujuba var. spinosa. After grinding, pass the material through a 75-mesh sieve and collect the material that passes through the sieve as material 1. (2) Mix the material 1 with water at a mass ratio of 1:7 and boil for 4 hours to obtain the filtrate; (3) The filtrate is concentrated under reduced pressure to an extract with a relative density of 1.20 at 65°C, and then dried at 85°C for 4 hours to obtain the final product.

[0035] Example 3

[0036] A traditional Chinese medicine compound feed additive for preventing early weaning stress syndrome in piglets, comprising the following components in parts by weight: 13 parts of Osmanthus fragrans, 13 parts of Astragalus membranaceus, 18 parts of Magnolia officinalis, 25 parts of Crataegus pinnatifida, 20 parts of Massa fermentata, 18 parts of Citrus reticulata peel, 13 parts of Polygala tenuifolia, 13 parts of Pulsatilla chinensis, 10 parts of Fraxinus chinensis, 18 parts of Poria cocos, 8 parts of Glycyrrhiza uralensis, and 13 parts of Ziziphus jujuba var. spinosa. The preparation method of the aforementioned traditional Chinese medicine compound feed additive includes the following steps: (1) Mix and grind the following ingredients: Osmanthus fragrans, Astragalus membranaceus, Magnolia officinalis, Crataegus pinnatifida, Medicated leaven, Citrus reticulata peel, Polygala tenuifolia, Pulsatilla chinensis, Fraxinus chinensis, Poria cocos, Glycyrrhiza uralensis and Ziziphus jujuba var. spinosa. After grinding, pass the material through a 65-mesh sieve and collect the material that passes through the sieve as material 1. (2) Mix the material 1 with water at a mass ratio of 1:6 and boil for 3 hours to obtain the filtrate; (3) The filtrate is concentrated under reduced pressure to an extract with a relative density of 1.16 at 65°C, and then dried at 80°C for 3 hours to obtain the final product.

[0037] Experimental Example 1

[0038] 1. Laboratory Animals and Grouping

[0039] Fifty 26-day-old weaned three-way crossbred piglets (from Taiyuan Hongxin Livestock Professional Cooperative) were selected and divided into 5 groups according to a completely randomized block design, with 10 replicates (pens) in each group, and the experimental period was 14 days.

[0040] The basic daily ration is formulated as follows: soybean meal 25%, fish meal 8%, whey powder 5%, wheat bran 9.7%, vegetable oil 2%, and the remainder corn.

[0041] The traditional Chinese medicine compound feed additive obtained by the method in Example 3 was used as the experimental group.

[0042] Control group 1 followed the same methods as in Example 3, except that nutmeg and Atractylodes macrocephala were used in equal amounts to replace Dryopteris crassirhizoma and Astragalus membranaceus.

[0043] Control group 2 followed the same methods as in Example 3, except that equal amounts of Platycladus orientalis seed and Coptis chinensis were used to replace Polygala tenuifolia and Pulsatilla chinensis.

[0044] Control group 3 followed the same methods as in Example 3, except that the addition of Ostreae Herba Dryopteris, Pulsatillae Herba and Fraxini Cortex was omitted.

[0045] The experiment consisted of 5 treatment groups, specifically: Blank control group: fed a basal diet without any additives; Drug group 1: basal diet + 1.5% of the traditional Chinese medicine compound feed additive of Example 3; Drug group 2: basal diet + 1.5% of the traditional Chinese medicine compound feed additive of control group 1; Drug group 3: basal diet + 1.5% of the traditional Chinese medicine compound feed additive of control group 2; Drug group 4: basal diet + 1.5% of the traditional Chinese medicine compound feed additive of control group 3; All groups in each experimental group were fed wet feed for 14 days. Piglets had free access to feed and water and were fed and immunized according to standard procedures.

[0046] Weigh the pigs at the beginning and end of the experiment and record the initial and final weights; calculate the diarrhea and mortality rates from weaning to the end of the experiment; record the initial and final weights and calculate the weight gain of the pigs.

[0047] At 8:00 AM on the last day of the experiment, under fasting conditions, three piglets were randomly selected from each replicate. 10 mL of blood was collected from each piglet via the anterior vena cava. After the blood was allowed to stand at room temperature for 0.5 hours, it was centrifuged at 3000 r / min for 15 minutes to separate the serum, which was then stored at -20℃ protected from light for later use. This serum was used to determine antioxidant indicators, serum hormone levels, and immunoglobulin levels.

[0048] The measured indicators included: total antioxidant capacity (T-AOC, colorimetric method), superoxide dismutase (SOD, hydroxylamine method), and malondialdehyde (MDA, TBA method). The reagent kits were provided by Nanjing Jiancheng Bioengineering Institute; porcine serotonin (5-HT), porcine cortisol, porcine gastrin (Gas), porcine immunoglobulin A (IgA), porcine immunoglobulin M (IgM), and porcine immunoglobulin G (IgG) were also tested. The ELISA kits were purchased from Taiyuan Fangcheng Laboratory Supplies Sales Department and were used according to the ELISA kit instructions. Diarrhea rate and mortality results are expressed as mean values, as shown in Table 1. Other results are expressed as mean ± standard deviation, as shown in Tables 2-4.

[0049] Table 1. Diarrhea Rate and Mortality Survey

[0050] Note: Data with the same superscript letter in the same column indicate no significant difference (ρ>0.05), adjacent data indicate significant difference (ρ<0.05), and data that are adjacent to each other indicate extremely significant difference (ρ<0.01).

[0051] Table 2 Pig Weight Gain Survey Form

[0052] Note: Data with the same superscript letter in the same column indicate no significant difference (ρ>0.05), adjacent data indicate significant difference (ρ<0.05), and data that are adjacent to each other indicate extremely significant difference (ρ<0.01).

[0053] Table 3. Antioxidant enzyme activity survey form

[0054] Note: Data with the same superscript letter in the same column indicate no significant difference (ρ>0.05), adjacent data indicate significant difference (ρ<0.05), and data that are adjacent to each other indicate extremely significant difference (ρ<0.01).

[0055] Table 4. Serum Hormone Levels and Immunoglobulin Indicators Survey Form

[0056] Note: If the same superscript letter is in the same row, the difference is not significant (ρ>0.05); if adjacent, the difference is significant (ρ<0.05); and if adjacent, the difference is extremely significant (ρ<0.01).

[0057] According to the results of the diarrhea rate and mortality survey shown in Table 1, the traditional Chinese medicine compound feed additive (drug group 1) prepared in Example 3 of this invention showed a significant advantage in preventing weaning stress syndrome in piglets, with a diarrhea rate and mortality rate of 0%, which was significantly better than the blank control group and other control groups. Although control groups 2 and 3 showed some improvement, they still had varying degrees of diarrhea and mortality, indicating that the compound of this invention has unique effects in anti-stress and intestinal protection.

[0058] As shown in Table 2, the piglets in drug group 1 had the highest weight gain, which was significantly higher than that of the blank control group and significantly higher than that of other drug groups. This indicates that the compound formula of this invention can effectively promote the growth performance of weaned piglets and improve feed utilization efficiency.

[0059] Table 3 shows that the antioxidant indicators in drug group 1 were the highest in total antioxidant capacity (T-AOC) and superoxide dismutase (SOD) activity, at 4.77 U / ml and 143.2 U / ml, respectively, significantly higher than drug group 3, highly significantly higher than the blank group, and other control groups. Drug group 1 had the lowest malondialdehyde (MDA) content (2.34 nmol / ml), significantly lower than drug group 3, highly significantly lower than the blank group, and other control groups. This indicates that the compound formula of this invention can effectively enhance the body's antioxidant capacity and reduce oxidative stress damage.

[0060] Table 4 shows serum hormone levels and immunoglobulin indicators, further confirming that drug group 1 had the highest levels of Gas, IgA, IgM, and IgG, at 318 pg / mL, 693.12 μg / mL, 4.17 mg / mL, and 4.68 mg / mL, respectively, significantly higher than the drug control group and extremely significantly higher than the blank control group. Drug group 1 also had the lowest levels of 5-HT and Cortis, at 458.60 pg / mL and 8.24 ng / mL, respectively, significantly lower than the drug control group and extremely significantly lower than the blank control group. This indicates that the compound formula can effectively improve the immune function of weaned piglets, enhance their stress resistance, and strengthen their overall immunity.

[0061] The above description is only a preferred embodiment of the present invention. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the principle of the present invention, and these improvements and modifications should also be considered within the scope of protection of the present invention.

Claims

1. A traditional Chinese medicine compound feed additive for preventing early weaning stress syndrome in piglets, characterized in that, The composition includes the following components in parts by weight: 10-15 parts of Osmanthus fragrans, 10-15 parts of Astragalus membranaceus, 15-20 parts of Magnolia officinalis, 20-30 parts of Crataegus pinnatifida, 15-25 parts of Massa fermentata, 15-20 parts of Citrus reticulata peel, 10-15 parts of Polygala tenuifolia, 10-15 parts of Pulsatilla chinensis, 8-12 parts of Fraxinus chinensis, 15-20 parts of Poria cocos, 5-10 parts of Glycyrrhiza uralensis, and 10-15 parts of Ziziphus jujuba var. spinosa.

2. The method for preparing the traditional Chinese medicine compound feed additive according to claim 1, characterized in that, Includes the following steps: (1) Mix and grind the following ingredients together: Os scutellaria, Astragalus membranaceus, Magnolia officinalis, Crataegus pinnatifida, Medicated leaven, Citrus reticulata peel, Polygala tenuifolia, Pulsatilla chinensis, Fraxinus chinensis, Poria cocos, Glycyrrhiza uralensis and Ziziphus jujuba var. spinosa to obtain material 1; (2) Mix the material 1 with water and boil to obtain a filtrate; (3) The filtrate is concentrated under reduced pressure to obtain an extract, which is then dried to obtain the final product.

3. The preparation method according to claim 2, characterized in that, The material after grinding in step (1) is passed through a 55-75 mesh sieve, and the material under the sieve is material 1.

4. The preparation method according to claim 2, characterized in that, In step (2), the mass ratio of material 1 to water is 1:4~7.

5. The preparation method according to claim 4, characterized in that, The simmering time in step (2) is 2 to 4 hours.

6. The preparation method according to claim 2, characterized in that, The extract obtained by step (3) is concentrated under reduced pressure to a relative density of 1.12~1.20 at 65°C.

7. The preparation method according to claim 2, characterized in that, The drying temperature in step (3) is 75~85℃.

8. The preparation method according to claim 2 or 7, characterized in that, The drying time in step (3) is 2 to 4 hours.

9. The application of the traditional Chinese medicine compound feed additive according to claim 1 in the preparation of weaned piglet feed.

10. The application according to claim 9, characterized in that, The traditional Chinese medicine compound feed additive is added to the weaned piglet feed at a mass ratio of 1.5 to 3.5%.