1 results about "Pathway activity" patented technology

This application relates to the field of bioinformatics computing technology, and discloses a method, device, computer equipment, and storage medium for predicting pathway activity status. The method includes: acquiring multi-omics data of a target object, wherein the multi-omics data includes multiple different omics entities; performing interaction strength analysis on each omics entity to obtain edge weight data between each omics entity; evaluating pathway activity on the edge weight data based on a pre-trained multilayer heterogeneous graph convolutional network to obtain pathway activity evaluation results of the edge weight data; and predicting the pathway activity status of the target object based on the activity evaluation results. This method can effectively capture the activity changes of genes in different omics entities, thereby improving the accuracy of biological pathway activity prediction.