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210 results about "Adenosine monophosphate" patented technology

Adenosine monophosphate (AMP), also known as 5'-adenylic acid, is a nucleotide. AMP consists of a phosphate group, the sugar ribose, and the nucleobase adenine; it is an ester of phosphoric acid and the nucleoside adenosine. As a substituent it takes the form of the prefix adenylyl-.

Method for regenerating ATP (adenosine triphosphate) by enzyme process and application thereof

The invention discloses a method for regenerating ATP by enzymatic method, which comprises the following steps: (1) preparing and obtaining ATP regenerating enzyme; (2) regenerating ATP in reaction liquid; (3) separating products and ATP regenerating enzyme. According to the method for regenerating ATP of the present invention, it has the following beneficial effects: (1) adopt three kinds of ATP regenerating enzymes of novel Ppk, Adk and Pap, the ATP consumed in the enzymatic reaction can be recycled and regenerated, greatly reducing the amount of ATP used, regenerated The process is simple and efficient, the reaction is easy to control, and the stability is high. (2) The substrate polyphosphoric acid or its salt to be added to the reaction is cheap and less polluting. (3) The enzymatic reaction does not need to add expensive ATP to start the reaction, add ADP or cheap AMP. (4) ATP regenerating enzyme recovery system was established, which is suitable for large-scale industrial production.
Owner:SHENZHEN GSH BIO TECH CO LTD

Medical prosthetic devices and implants having improved biocompatibility

A medical prosthetic device or medical implant containing a metal material (A) selected from the group consisting of titanium or an alloy thereof, zirconium or an alloy thereof, tantalum or an alloy thereof, hafnium or an alloy thereof, niobium or an alloy thereof and a chromium-vanadium alloy, wherein surface parts of the metal material (A) are coated with a layer of a corresponding hydride material (B) selected from titanium hydride, zirconium hydride, tantalum hydride, hafnium hydride, niobium hydride and chromium and/or vanadium hydride, respectively, said device or implant being characterised in that the layer of hydride material (B) comprises one or more biomolecule substances (C) associated therewith. The device or implant exhibits improved biocompatibility. The metal material (A) is preferably titanium. The biomolecule substance (C) may be selected from the following types of substances: Natural or recombinant bio-adhesives; natural or recombinant cell attachment factors; natural, recombinant or synthetic biopolymers; natural or recombinant blood proteins; natural or recombinant enzymes; natural or recombinant extracellular matrix proteins; natural or synthetic extracellular matrix biomolecules; natural or recombinant growth factors and hormones; natural, recombinant or synthetic peptide hormones; natural, recombinant or synthetic deoxyribonucleic acids; natural, recombinant or synthetic ribonucleic acids; natural or recombinant receptors; enzyme inhibitors; drugs; biologically active anions and cations; vitamins; adenosine monophosphate (AMP), adenosine diphosphate (ADP) or adenosine triphosphate (A TP); marker biomolecules; amino acids; fatty acids; nucleotides (RNA and DNA bases); and sugars.
Owner:NUMERICAL TECH INC

Low-carbon energy-saving latex paint and preparation method thereof

The invention discloses a low-carbon energy-saving latex paint and a preparation method thereof. The low-carbon energy-saving latex paint comprises water, hydroxyethyl cellulose thickener, AMP(adenosine monophosphate)-95 multifunctional assistant, wetting dispersant, defoamer, film-forming assistant, glycol, titanium pigment, 600-mesh triple superphosphate, calcined kaolin, talcum powder, vinyl acetate-acrylate copolymer emulsion, preservative and mildew inhibitor. The preparation method comprises the following steps: A. proportionally adding water into a stirred tank, sequentially adding the hydroxyethyl cellulose thickener, multifunctional assistant, wetting dispersant, defoamer, film-forming assistant and glycol, and dispersing at a medium speed; B. adding the titanium pigment, 600-mesh triple superphosphate, calcined kaolin and talcum powder, and dispersing at a high speed until the degree of fineness is less than 50 mu m; and C. dispersing at a low speed, adding the vinyl acetate-acrylate copolymer emulsion, preservative and mildew inhibitor, and evenly stirring to obtain the low-carbon energy-saving latex paint. The product disclosed by the invention has the advantages of high solid content, low VOC (volatile organic compound), light smell, and favorable film-forming property, and is environment-friendly, low-carbon and energy-saving, and is healthy.
Owner:中山市丽莎涂料有限公司

Hydrothermal method synthesized photosensitive gold-silver alloy nanocluster adopting micromolecular adenosine monophosphate as protection ligand

The invention discloses a hydrothermal method synthesized photosensitive gold-silver alloy nanocluster adopting micromolecular adenosine monophosphate as a protection ligand, and belongs to the technical field of preparation of gold-silver alloy nanoclusters. The photosensitive gold-silver alloy nanocluster is prepared through the steps of sequentially adding an adenosine monophosphate solid sample, deionized water, a chloroauric acid aqueous solution, a silver nitrate aqueous solution and a sodium citrate aqueous solution into a reaction kettle, wherein adenosine monophosphate is the protection ligand, and sodium citrate is adopted as a reducing agent and reduces trivalent gold ions into nulvalent and univalent gold; after hydrothermal reaction, slowly cooling a reactant to the room temperature, so as to obtain a gold-silver alloy nanocluster product adopting micromolecular adenosine monophosphate as the protection ligand; and carrying out purification through an acetone precipitation method or dialysis method, so as to obtain a target product. The adenosine monophosphate protected fluorescent gold-silver alloy nanocluster has the advantages that operation is simple, efficient, time-saving, eco-friendly and environmentally-friendly and photosensitivity is achieved, the nanocluster gives out orange light, fluorescent quantum yield is relatively high, and the nanocluster has relatively large application potentials in the aspect of biology.
Owner:JILIN UNIV

Electroluminescence logic gate adopting adenosine monophosphate and adenosine deaminase as excimers

The invention relates to electrochemiluminescence DNA logic gate constructed by adopting adenosine monophosphate and adenosine deaminase as excimers based on a specific binding effect of a aptamer and a ligand thereof, and a deamination effect of adenosine deaminase, wherein adenosine monophosphate aptamer-containing single-stranded DNA and two single-stranded DNA modified with a luminescence agent and a quenching agent are subjected to hybridization to form the DNA logic gate. According to the present invention, after adenosine monophosphate and the aptamer thereof are subjected to specific binding, the luminescence agent-modified single-stranded DNA is released, and is captured by the carbon nanotube-modified electrode so as to enhance the electrochemiluminescence signal; adenosine deaminase is added to catalyze deamination of adenosine monophosphate so as to destruct the binding effect of the adenosine monophosphate and the aptamer, and the aptamer and the luminescence agent-modified single-stranded DNA form the hybrid so as to separate from the electrode and reduce the electrochemiluminescence signal; and through the improvement of the logic gate structure and the introduction of the quenching agent, the background interference is reduced, and the detection sensitivity is improved.
Owner:LINYI UNIVERSITY

Protein protectant

The invention provides a series of protein protective solutions which are capable of effectively protecting the activity of Hsp90 (Heat Shock Protein90) alpha protein and increasing the stability of the Hsp90alpha protein and are invariant under the concentration in nanogram level. On the basis of a traditional protein protectant, other protectant components are added in the protein protective solutions, and the other protectant components are selected from AMP (Adenosine Monophosphate), heparin sodium, MgCl2, PVP40 (Polyvinylpyrrolidone 40), tea polyphenol, cyclodextrin and K2SO4.
Owner:YANTAI PROTGEN BIOTECH DEV

Health-care instant powder for people suffering from hyperlipidemia, hypertension and hyperglycemia and preparation method of health-care instant powder

The invention discloses health-care instant powder for people suffering from hyperlipidemia, hypertension and hyperglycemia. The health-care instant powder is prepared from raw materials as follows: dendrobium officinale, soybean meal, tea powder, kelp powder, tapioca flour, rice bran, fish oil, mushroom powder, laver powder, spina date seeds, bitter gourd powder, peach kernel powder, oat meal, cyclocarya paliurus leaves, ginseng, tuber fleeceflower roots, safflower, Chinese angelica, szechuan lovage rhizomes, fructus lycii, twotooth achyranthes roots, roots of redsepal eveningprimrose, pseudo ginseng, hawthorn fruits, lotus leaves, ginkgo leaves, pinellia tuber, cassia seeds, liquorice, pinus densiflora leaves, hemp fruits, persimmon leaves, parslane herbs, beewax, bottle brush herbs, wintercherries, dahurian rose fruits, motherwort herbs, earthworms, eucommiae folium, kudzuvine roots, cellulase, pectinase, black fungus polysaccharide extracts, a vitamin mixture, dextrin, 6-hydroxyflavanone, steviosin, adenosine monophosphate and mannitol. The invention further provides a preparation method of the health-care instant powder for people suffering from hyperlipidemia, hypertension and hyperglycemia. The health-care instant powder containing dendrobium officinale tastes mellow and sweet and can effectively reduce lipid, blood pressure and blood glucose of people suffering from hyperlipidemia, hypertension and hyperglycemia.
Owner:安徽皖斛堂生物科技有限公司

Fluorescent probe for selectively identifying ATP based on aggregation-induced fluorescence enhancement characteristic, synthetic method and application thereof

ActiveCN106814057AOvercoming easy bleachingOvercoming detectionFluorescence/phosphorescenceHigh concentrationATP Hydrolase
The invention discloses a fluorescent probe for selectively identifying ATP (adenosine triphosphate) based on an aggregation-induced fluorescence enhancement characteristic, a synthetic method and an application thereof. The fluorescent probe 1 is synthesized by taking a benzophenone derivative as a starting material. The invention carries out a detection research on ATP, ADP (adenosine diphosphate), AMP (adenosine monophosphate) and pyrophosphoric acid (PPi) with the fluorescent probe 1, and discoveries that the fluorescent probe has very good sensitivity and selectivity to ATP; compared with the prior art, the invention has the advantages that the synthetic raw material is easy to obtain, the fluorescent probe has high fluorescence quantum yield and strong photobleaching resistance, and the like, and avoids the defect that a conventional fluorescent dye is not suitable for detection under a high concentration; in addition, the fluorescent probe 1 is successfully used for monitoring a reaction process of ATP hydrolase Apyrase in a solution, and is also used for imaging research of ATP in cells. Therefore, the fluorescent probe 1 has a great application prospect in the aspect of detecting the content of in vivo ATP.
Owner:GANNAN NORMAL UNIV
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