103 results about "Deamination" patented technology

The invention relates to a low-molecular-weight chondroitin sulfate composition as well as a preparation method and application thereof, and aims to solve the problems that a chondroitin sulfate product obtained by a single degradation mode is limited in function and difficult to synergistically regulate intestinal barriers. The preparation method comprises the following steps: firstly, preparing LMCSO through oxidative degradation; secondly, preparing LMCSH through hydrothermal degradation; and finally, the LMCSD is prepared through deamination degradation. Finally, the obtained LMCSO, LMCSH and LMCSD are compounded according to the weight ratio of 5: 3: 2, and the low-molecular-weight chondroitin sulfate composition LMCSs-C is obtained. The composition LMCSs-C prepared by the invention can synergistically improve the intestinal barrier function through multiple action mechanisms, not only shows an obvious intestinal barrier repair effect in vitro and animal models, but also has good biocompatibility and safety, and shows a wide application prospect in intestinal health maintenance and related disease intervention.

The invention provides a non-disease diagnosis purpose 5-hydroxymethylcytosine 5hmC detection method and a non-disease diagnosis purpose 5-hydroxymethylcytosine 5hmC detection kit. The detection method comprises the following steps: S1, glycosylation treatment; s2, carrying out enzyme digestion treatment on the GSREs; s3, carrying out APOBEC deamination treatment; s4, carrying out hydroxymethylation detection; the kit comprises a glycosylation reaction kit, a GSREs enzyme digestion reaction kit, an APOBEC deamination reaction kit and a PCR (Polymerase Chain Reaction) kit. The glycosylation reaction kit comprises a CutSmart buffer solution, UDP-Glucose, a T4-BGT enzyme and nuclease-free water, wherein the CutSmart buffer solution, the UDP-Glucose and the T4-BGT enzyme are used as raw materials; the GSREs enzyme digestion reaction kit comprises a GSREs enzyme, an enzyme digestion reaction buffer solution and nuclease-free water, the APOBEC deamination reaction kit comprises APOBEC, BSA (Bovine Serum Albumin), an APOBEC Reactive buffer solution and nuclease-free water; the PCR kit comprises a PCR reaction solution, a primer and a probe. According to the 5-hydroxymethylcytosine 5hmC detection method and kit for non-disease diagnosis purpose provided by the invention, precise quantification of extremely high specificity of 5hmC is realized, and the detection sensitivity is also improved while the specificity of a detection signal is improved.

The invention discloses a sulfur-oxidizing bacterium screening and enriching nutrient solution, a sulfur-oxidizing bacterium enriching method and a deodorizing method. The sulfur-oxidizing bacterium screening and enriching nutrient solution comprises 1.0 g.L <-1 > of K2HPO4, 0.5 g.L <-1 > of NaHCO3, 0.05 g.L <-1 > of NH4Cl, 0.225 g.L <-1 > of Na2S. 9H2O and 0.001 g.L <-1 > of trace elements, wherein the trace elements comprise 0.5 g.L <-1 > of EDTA (Ethylene Diamine Tetraacetic Acid), 0.01 g.L <-1 > of (NH4) 6Mo7O24. 4H2O, 0.04 g.L <-1 > of ZnSO4. 7H2O, 0.03 g.L <-1 > of MnCl2. 7H2O, 0.02 g.L <-1 > of CuSO4. 5H2O The deodorization performance of the municipal sewage treatment plant is improved through synchronous desulfurization and deamination of the acidophilic sulfur-oxidizing bacteria, and compared with a traditional deodorization process, the synchronous desulfurization and deamination process can enrich high-abundance sulfur-oxidizing bacteria in a short time and shows higher ammonia gas and hydrogen sulfide removal capacity.

The invention discloses a method for deeply removing total nitrogen in water through autotrophic-heterotrophic sulfur denitrification and application, and relates to the technical field of sewage treatment deep deamination. Comprising the following steps: S1, putting a suspended sulfur carrier into a biological contact oxidation pond; s2, sulfur autotrophic denitrification strains are added into the biological contact oxidation pond, the adding amount of the strains is 2-5 kg / m < 3 > of a carrier, and stuffy aeration is conducted for 48-240 hours after water is fed; s3, after changing the water, adding a sulfur heterotrophic denitrification strain into the biological contact oxidation pond according to the addition amount of 2-3 kg / m < 3 > of the carrier, and carrying out stuffy aeration for 24-48 hours; s4, group sensing factors are added into the biological contact oxidation pond, the adding amount is 0.01-0.03 / kg / m < 3 >, and stuffy aeration is conducted for 24 h; and S5, introducing to-be-treated sewage for denitrification. According to the sewage treatment method disclosed by the invention, under the condition that the organic matter content (COD value) is relatively low, a carbon source does not need to be additionally added to remove total nitrogen, so that the effluent reaches the IV-class standard of surface water.

The present invention relates to antisense oligonucleotides (AONs) that can mediate RNA editing by binding to a target RNA nucleic acid molecule, preferably an RNA transcript molecule, in a cell and recruiting an endogenous deaminating enzyme in the cell to deaminate a target adenosine in the target RNA molecule to an inosine. The target RNA molecule is a transcript molecule form the SLC10A1 gene that encodes the Na+ / Taurocholate Co-transporting Polypeptide (NTCP), and the target adenosine is the adenosine in the GAC codon coding for aspartic acid (D) at position 24 of the NTCP protein. The deamination of the adenosine changes the amino acid to a glycine (G). The RNA editing of the adenosine will result in a loss-of-function of the NTCP protein, which will result in lowered uptake of bile acids from the portal circulation into the liver, thereby lowering the risk of suffering from disorders related to bile accumulation in the liver.

The invention discloses a preparation method and application of a metal carrier loaded with deamination tyrosine, the preparation method comprises the following steps: ZrOCl28H2O, TCPP and benzoic acid with a specific ratio and concentration are synthesized into Zr-MOFs with a specific particle size and structure, then the Zr-MOFs react with deamination tyrosine with a certain concentration, and DAT-Zr-MOF is prepared through a two-step method. The prepared DAT (at) Zr-MOF loaded deamination tyrosine is high in content and good in stability, can effectively solve the problem that deamination tyrosine is subjected to enzymolysis and oxidation, and can be used for treating wounds and promoting tissue repair through external application.

The invention relates to the technical field of high-concentration ammonia nitrogen wastewater treatment, and discloses a device and a method applied to anaerobic ammonia oxidation strain enrichment culture, the device comprises a biological reaction tank, a heater, an online monitoring probe and a filter element arranged in the biological reaction tank, the on-line monitoring probe is used for monitoring the pH value, the temperature value and the dissolved oxygen content in the biological reaction tank; the heater is used for heating the biological reaction tank, the biological reaction tank is provided with a water inlet and a water outlet, the filter element is used for enriching anaerobic ammonia oxidation granular sludge in the biological reaction tank, and a liquid outlet of the filter element is communicated with the water outlet. According to the scheme, bacterial sludge is enriched through the filter element, and the retention time of the bacterial sludge is furthest realized, so that the deamination treatment load of the device is improved; the device has the advantages of high effective volume utilization rate and stable effluent quality, and is widely applicable to denitrification treatment of industrial wastewater with high ammonia nitrogen, low carbon nitrogen ratio and high suspended solids.

The invention belongs to the technical field of synthesis of ester compounds, and particularly relates to a preparation method of 2, 6-dichloro-4-cyanobenzoic acid methyl ester, which comprises the following steps: by taking dimethyl 2-aminoterephthalate as a raw material, sequentially carrying out substitution reaction, deamination reaction, hydrolysis reaction, amidation reaction and dehydration reaction to obtain the 2, 6-dichloro-4-cyanobenzoic acid methyl ester. The 2, 6-dichloro-4-cyanobenzoic acid methyl ester is prepared by the method, and the yield reaches 59.28%. The N-chlorosuccinimide is used as a chlorine source to carry out substitution reaction on the 2-amino dimethyl terephthalate, so that the potential safety hazard caused by the traditional chlorination reagent is avoided, and the tert-butyl nitrite used in the deamination reaction avoids the potential safety hazard caused by the use of strong corrosive sulfuric acid; the amidation reaction is completed in one step by adopting a condensing agent, so that the complicated operation caused by firstly preparing acyl chloride and then carrying out condensation reaction is avoided, and therefore, the preparation method has the characteristics of safe preparation process, environment friendliness, simplicity in operation and the like under the condition of ensuring the product yield and purity.

This utility model discloses a ternary precursor material mother liquor ammonia removal treatment system, including an ammonia removal tower, a falling film evaporator, a dilute ammonia water tank, a condenser, and an ammonia water storage tank. The top of the ammonia removal tower is connected to the shell side of the falling film evaporator section via an ammonia gas outlet pipe, and the bottom of the ammonia removal tower is connected to the gas-liquid separation section via a liquid outlet pipe. The shell side of the falling film evaporator section is connected to the cooling inlet end of the condenser via an ammonia gas outlet pipe, and the cooling outlet end of the condenser is connected to the ammonia water storage tank. A dilute ammonia water inlet pipe and a reflux pipe are connected between the shell side of the falling film evaporator section and the top of the dilute ammonia water tank. A liquid outlet pipe is connected to the gas-liquid separation section. A reflux pipe and a falling film circulation pump are connected between the liquid outlet pipe and the top of the tube side of the falling film evaporator section. A vapor compression unit is provided between the gas-liquid separation section and the ammonia removal tower. This utility model has the advantages of reducing the amount of vapor used in the ammonia removal tower, reducing energy consumption, achieving good ammonia removal effect from the mother liquor, achieving good ammonia water recovery effect, low system operating cost, and stable and reliable operation.

The invention relates to a preparation method of N-alpha-t-butyloxycarboryl-L-lysine (N-alpha-t-butyloxycarboryl). The preparation method of the N-alpha-t-butyloxycarbonyl-L-lysine comprises the following steps: mixing L-lysine hydrochloride with hyperbranched aromatic borate, reacting under the action of a phosphate buffer solution and N, N-dimethylformamide to obtain an intermediate b, mixing the intermediate b with benzyl halide, reacting under the action of alkali and a solvent I to obtain an intermediate c, and reacting under the action of a solvent II to obtain the N-alpha-t-butyloxycarbonyl-L-lysine. The intermediate c, a phosphate buffer solution and N, N-dimethylformamide are mixed and then react to obtain an intermediate d, the intermediate d and di-tert-butyl dicarbonate ester are mixed and then react under the action of alkali and a second solvent to obtain an intermediate e, and the intermediate e and ferric chloride react in a third solvent to obtain the ferric chloride. The preparation method comprises the following steps: protecting alpha-amino and carboxyl by using L-lysine hydrochloride and hyperbranched aromatic borate, performing benzyl protection on epsilon-amino, performing boron removal protection, reacting alpha-amino with di-tert-butyl dicarbonate, and performing epsilon-aminobenzyl removal protection to obtain N-alpha-tert-butyloxycarboryl-L-lysine.

The present invention relates to a low-molecular-weight chondroitin sulfate composition, its preparation method, and application, aiming to address the problem that chondroitin sulfate products obtained by a single degradation method have limited functions and are difficult to synergistically regulate the intestinal barrier. The preparation method first prepares LMCSO by oxidative degradation; secondly, prepares LMCSH by hydrothermal degradation; and finally, prepares LMCSD by deamination degradation. Finally, the obtained LMCSO, LMCSH, and LMCSD are compounded in a weight ratio of 5:3:2 to obtain a low-molecular-weight chondroitin sulfate composition LMCSs-C. The composition LMCSs-C prepared by the present invention can synergistically improve intestinal barrier function through multiple mechanisms of action. It not only demonstrates significant intestinal barrier repair effects in vitro and in animal models, but also has good biocompatibility and safety, showing broad application prospects in maintaining intestinal health and intervening in related diseases.

This invention discloses a method for the deamination functionalization of aliphatic nitrosamines, comprising: reacting an aliphatic nitrosamine as shown in formula (II) with a nucleophile in the presence of an acid and a solvent to generate a deamination functionalized product as shown in formula (III); wherein, R 1 R 2 R 3 Each group is independently selected from hydrogen, hydroxyl, alkyl, alkoxy, alkanoyl, alkoxycarbonyl, alkylsulfinyl, alkylsulfonyl, aryl, heteroaryl, phenylalkyl, or R 1 R 2 R 3 Two or three of the functional groups form a non-aromatic ring, cage-like compound; FG is a functional group in which a nucleophile participates in the reaction. The method of this invention has the advantages of inexpensive and readily available raw materials, simple reaction conditions, and wide substrate applicability.

The invention discloses application of a methyltransferase mutant and deaminase in DNA methylation single base resolution sequencing, and relates to the technical field of gene sequencing. On the basis of a methyltransferase mutant M.MedI-N377K, cytosine at a CG site in DNA (Deoxyribonucleic Acid) can be specifically recognized, and carboxymethyl of carboxyl-S-adenosine-L-methionine (caSAM) is transferred to a C5 site of C in the CG, so that the 5-carboxymethyl cytosine is generated. 5-methylcytosine can be subjected to deamination by deaminase to form thymine, and the thymine is paired with adenine in subsequent PCR amplification; and 5cam C can resist deamination of A3A and is paired with guanine in subsequent PCR (Polymerase Chain Reaction), and 5mC is read as T and C is read as C in a subsequent Sanger sequencing result of an amplification product, so that C and 5mC in DNA (Deoxyribonucleic Acid) are distinguished. The method disclosed by the invention is high in sensitivity, good in specificity and simple to operate, does not involve hydrosulfite treatment, and can be used for carrying out positioning analysis on 5mC in a biological sample under a single-base resolution ratio.

The utility model discloses a device for catalytic removal of ammonia nitrogen based on a novel surface activity denitrification agent. The device mainly comprises an ammonia nitrogen catalytic removal reaction device and an ammonia nitrogen catalytic removal collection device, the ammonia nitrogen catalytic removal reaction device comprises a reaction chamber, an openable and closable slag discharge port, a powerful stirrer motor, a water pump and a water discharge pipe, wherein the reaction chamber is formed by enclosing a heat dissipation wall body and is provided with an open top; a cover plate is arranged at the top of the reaction chamber, a powerful stirrer motor is fixedly mounted on the cover plate, and the cover plate is provided with a water inlet, a feed port, a feed port, a surface activity denitrification agent sample inlet and an exhaust port; the lower part of the reaction chamber is provided with an openable slag discharge port; a water outlet is further formed in the portion, above the slag discharging opening capable of being opened and closed, of the wall body capable of dissipating heat. And the ammonia nitrogen catalytic removal and collection device comprises an ammonia spray tower. The device is economical and practical, is convenient to install and construct, can be flexibly set in size according to the actual water treatment amount and the sample injection amount, and can realize efficient ammonia nitrogen catalytic removal.

The present invention relates to a kit for gently detecting 5hmC and a detection method thereof. The kit includes: a blocking reaction solution, an APOBEC deamination conversion solution, a pyridine borane conversion solution, a ligation reaction solution, and an amplification reaction solution; the ligation reaction solution includes probe A and probe B. First, the present invention uses glucosyltransferase to modify uridine diphosphate-glucose (UDP-Glu) on the hydroxyl group of 5hmC to form 5gmc, protecting 5hmC from being affected by subsequent reactions. Then, APOBEC is used to deaminate C and 5mC into uracil (U), and 5fC and 5caC are converted into dihydrouracil (DHU) by pyridine borane. U and DHU are complementary base-paired with A base, while 5gmc is still paired with G, so that 5hmC forms a single-base difference from other bases. The high-sensitivity detection of 5hmC is carried out by loop-mediated isothermal amplification (LAMP) based on ligation. The detection method of the present invention is gentle and efficient, can detect 5hmC as low as 2 fM, and the specificity reaches 1%.

The invention relates to the technical field of landfill leachate treatment, and discloses a landfill leachate full-quantitative treatment method and an electrocatalytic oxidation device thereof.The landfill leachate full-quantitative treatment method comprises the following steps that pretreatment is conducted, and landfill leachate raw water enters a regulating reservoir to be subjected to homogenization and primary hydrolytic acidification; meanwhile, large-particle substances and suspended matters in the landfill leachate are removed; biochemical treatment: the pretreated leachate enters a biochemical system to be subjected to biochemical treatment, so that the leachate is subjected to deamination and dephosphorization, and easy organisms and organic matters are degraded; membrane treatment: enabling the leachate subjected to biochemical treatment to pass through a membrane filtration system so as to intercept organic pollutants and salt in the leachate, and discharging the produced water after the produced water reaches the standard; and concentrated solution treatment: enabling the concentrated solution generated in the membrane filtration system to enter an electrocatalytic oxidation device for electrocatalytic oxidation, then discharging the concentrated solution with the effluent reaching the standard, and enabling the concentrated solution with the effluent not reaching the standard to flow back to the biochemical system to participate in treatment again. According to the invention, the efficiency of landfill leachate treatment can be improved.

The application discloses a method for recovering terephthalic acid from polyester-containing products, which comprises the following steps: (a) performing an enzymatic reaction by contacting the polyester-containing products with a degradation enzyme, using ammonia water / ammonia gas / liquid ammonia / ammonium hydroxide as a pH regulator in the enzymatic reaction, and forming a degradation solution containing ammonium terephthalate and a dihydric alcohol after the enzymatic reaction; (c) performing a heating treatment on the degradation solution; and (d) obtaining solid terephthalic acid through solid-liquid separation. Through the cycle mode of water dissolution-reconcentration-again deamination, the total recovery rate of PTA is significantly improved to more than 90%, efficient utilization of materials is realized, and the whole process still does not need to add acid and alkali, no waste salt is generated, and the process is green and economical.

The utility model discloses an energy-saving deamination and ammonia water recovery device, which is applied to the field of chemical separation and comprises a deamination shell, a liquid inlet pipe and a flora inlet are arranged on the deamination shell, a liquid discharge pipe is arranged on the lower surface of the deamination shell, a temperature adjusting mechanism and a stirring mechanism are arranged in the deamination shell, and the stirring mechanism is arranged on the lower surface of the deamination shell. The temperature adjusting mechanism extends into the deamination shell through a liquid discharging pipe, an ammonia water recycling mechanism is arranged on one side of the deamination shell, during use, ammonia-containing wastewater is firstly discharged into the deamination shell through a liquid inlet pipe, then flora is discharged into the deamination shell through a flora inlet, and the ammonia water recycling mechanism is arranged on the other side of the deamination shell. Ammonia is converted into nitrate ammonia by utilizing nitrifying bacteria, then the nitrate ammonia is reduced into ammonia gas to be discharged by utilizing denitrifying bacteria, the temperature in the deamination shell can be adjusted by the temperature adjusting mechanism, so that the temperature is suitable for growth of flora and the activity of the flora is maintained, and then the flora can be fully contacted with ammonia-containing wastewater by the stirring mechanism, so that the treatment efficiency is improved.

The present invention discloses a bio-based high-strength solvent-resistant hyperbranched adhesive and a preparation method thereof, belonging to the field of bonding technology. The present invention prepares a hyperbranched polymer containing rich amino functional groups by deamination polycondensation reaction, and crosslinks it with glycerol triglycidyl ether through addition to obtain the high-strength, solvent-resistant bio-based hyperbranched adhesive MDUG adhesive of the present invention. The adhesive prepared by the present invention is widely applicable to bonding various materials, has high bonding strength and good solvent resistance, and the bonded substrate can also maintain its stability in extremely cold or high temperature environments (-196°C to 100°C), and adopts a simple solvent-free synthesis method, is easy to operate, and has low cost.

The invention relates to the technical field of microorganism culture and screening, and discloses a culture medium, a preparation method thereof and application of the culture medium in screening mineralized microorganisms, and the culture medium contains peptone, yeast extract powder, sodium chloride, magnesium chloride and calcium chloride. The culture medium takes peptone and yeast extract powder as core components, is not only suitable for screening urealysis type mineralized bacteria, but also provides nutrient substances required by growth of amino acid deamination, carbonic anhydrase catalysis or heterotrophic metabolism driven type mineralized microorganisms, comprehensively screens and prevents potential mineralized bacteria from being omitted. The culture medium can be used for accurately and efficiently screening metal surface mineralizable microorganisms. According to the culture medium, the ecological adaptability of marine strains is optimized, peptone and yeast extract powder supply nutrient substances needed by growth of marine bacteria, sodium chloride, magnesium chloride and calcium chloride are mainly used for simulating the marine salinity environment and adjusting the osmotic pressure and enzyme activity of the bacteria, the matching degree with the environment is high, and the enrichment efficiency is high.

A high pressure melamine production process wherein treating crude melamine comprises separating solid melamine from a mother liquor (1) comprising water, ammonia, carbon dioxide, residual melamine and OAT; the treatment of the mother liquor comprises deamination (100) and treatment of an ammonia depletion solution (4) in an OAT decomposition section (200); a purification treatment (300) of the OAT-depleted stream (6) produces a vapor stream (7) containing ammonia, CO2 and water and a first liquid stream (8) and a second liquid stream (9); said first liquid stream (8) comprising residual ammonia and having a CO2 concentration not greater than a target concentration; the second liquid stream (9) has an ammonia concentration not greater than a target concentration; at least part of the first liquid stream and / or at least part of the second liquid stream is recycled to the melamine production process.

The present application relates to the technical field of chemical separation, and discloses a methylamine separation and purification system and method, which can efficiently destroy hydrogen bond association system by accurately controlling flash evaporation pressure, temperature and material residence time, can recover the extraction water after removing trace organic impurities, can recover the extraction agent polarity and selectivity, can guarantee the stable separation efficiency of trimethylamine, can cut off the cross-unit pollution path from the source, can slow down the tower scaling and improve the mass transfer efficiency, can simultaneously match the whole process parameter monitoring system, can collect the operation parameters of each tower, product purity, impurity removal rate and hydrogen bond dissociation rate, can calculate the system running cycle and failure probability based on the data, and can propose the product purity stability and system energy consumption optimization strategy, so as to dynamically control the operation parameters of the whole link such as deamination, extraction, separation and recovery, and guarantee the stable output of high-purity methylamine product and the long-period continuous operation of the system.

The application discloses a system and method for extracting ammonia from solvent regenerator overhead reflux to a deamination tower, and belongs to the technical field of solvent regeneration. The system comprises a solvent regenerator, a deamination tower, a reboiler, a water cooler, a first circulating pump, a second circulating pump and a static mixer. The pipeline connecting the first circulating pump and the water cooler is connected with the pipeline connecting the second circulating pump and the static mixer through an ammonia extraction pipeline. The ammonia collected at the top of the regenerator affects the desulfurization effect of the solvent. In the application, the ammonia water collected at the top of the regenerator is sent to the deamination tower for treatment, so that the ammonia nitrogen and hydrogen sulfide contents in the amine solution after regeneration are reduced, and the amine regeneration effect is ensured. The application of the solvent regenerator overhead reflux ammonia extraction to the deamination tower to a hydrogenation device for removing hydrogen sulfide in circulating hydrogen can solve the common problem of poor desulfurization effect, and can also be applied to other naphthenic base distillate hydrogenation devices of various tonnages.

The invention discloses a method for jointly preparing silazacyclopentane silane and alkoxy trialkylsilane, which comprises the following steps of: firstly, promoting intramolecular coupling of amino silane by adding a main catalyst and an auxiliary catalyst so as to reduce the reaction temperature and time; amino alkoxy silane and excessive hexaalkyldisilazane are used as raw materials, a trialkylsilyl substituted unstable intermediate structure is formed through deamination, then cyclization reaction is carried out, alkoxy trialkylsilane fraction and silazacyclopentyl silane distillate are obtained in sequence, energy consumption is remarkably reduced, the process difficulty is reduced, and the yield is increased. The problem that the conventional amino silane easily causes difficult product storage or inactivation is solved, the problems that silazacyclopentyl silane is high in preparation difficulty and difficult to separate are solved, and the obtained alkoxy trialkylsilane can obtain economic benefits after being purified and distributed.

The invention belongs to the technical field of wastewater treatment and utilization, and relates to a double-tower coupled coal chemical industry wastewater deacidification and deamination process, to-be-treated wastewater is divided into a cold part and a hot part to enter a deacidification tower from the upper part and the middle upper part of the deacidification tower respectively, deacidification tower kettle liquid without most acidic gas is pumped to the upper part of a deamination tower, and the deamination tower kettle liquid is pumped to the lower part of the deamination tower; after ammonia-containing water vapor is stripped from the top of the deamination tower, one part of the ammonia-containing water vapor enters the multi-stage segregation device, and the other part of the ammonia-containing water vapor enters the tower kettle of the deacidification tower to be used as a heat source of the deacidification tower; the segregation device is also connected with an ammonia water vapor compressor, and part of ammonia-containing water vapor is boosted to be slightly higher than the pressure of the tower kettle of the deacidification tower and then enters the deacidification tower. According to the process disclosed by the invention, deacidification and deamination are carried out in two towers, meanwhile, the deacidification tower is not provided with a reboiler, and a part of ammonia water vapor separated from the deamination tower is selected to enter the deacidification tower, so that a heat source is provided on one hand, and the reaction is more thorough through the disturbance action of gas on the other hand; and heat loss caused by the fact that waste gas directly flows out from the top of the deacidification tower is reduced or prevented.

The application belongs to the technical field of organic synthesis and specifically relates to a preparation process of high-efficiency taurine. The process specifically comprises the following steps: S1, raw material solution preparation and mother liquor threshold reuse; S2, construction of an aminolysis selective chemical environment; S3, aminolysis reaction; S4, deamination and clarification filtration; S5, segmented acidification-crystallization coupling; S6, crystal throwing and controlled cooling crystallization; S7, solid-liquid separation, washing and drying; and S8, mother liquor threshold detection and closed-loop reuse. The application constructs an aminolysis selective control, acidification-crystallization purification and mother liquor threshold reuse synergistic closed-loop process, stably controls a reaction system, dynamically determines an end point, and inhibits by-product generation from the source; segmented acidification and temperature-controlled crystallization are adopted to improve the purity of crystals and the first-time pharmaceutical-grade qualified rate; and the mother liquor is recycled according to a multi-index threshold access, thereby blocking impurity accumulation.

An emission reduction device for ammonia in granulation exhaust gas from a urea production device. The emission reduction device comprises a combined tower body (1), a deamination section (2) arranged at a lower portion inside the combined tower body (1), and an ammonia recovery section (3) arranged at an upper portion inside the combined tower body; and further comprises a partition plate (7) and a gas riser (8) that are arranged between the deamination section (2) and the ammonia recovery section (3), wherein the deamination section (2) and the ammonia recovery section (3) are in gas phase communication but not in liquid phase communication. The emission reduction device can be flexibly mounted in a granulation tower or a granulation plant, has low investment costs and operation costs, and has a prolonged service life.

The invention belongs to the field of biological medicine, and particularly relates to a 12-bit deamination esterification impurity of terlipressin for injection and application. The deamination and esterification impurity is a terlipressin 12-site deamination and esterification compound generated by reaction of terlipressin 12-site amination glycine and mannitol, the molecular weight of a single isotope is 1391.5510, and the structural formula of the deamination and esterification impurity is shown as a formula I. The deamination and esterification impurity is a terlipressin 12-site deamination and esterification compound.

The invention relates to the technical field of wastewater treatment, and particularly discloses a biological deamination treatment process based on an iron-carbon coupling method. The invention discloses a biological deamination treatment process based on an iron-carbon coupling method. The biological deamination treatment process comprises the following steps: pretreatment: filling a reactor with iron-carbon composite filler with a sandwich structure; then circularly contacting the surface of the filler with an iron reducing bacteria solution and a sulfur autotrophic bacteria solution, and culturing and biofilm culturing to form a composite membrane; wherein the iron-carbon composite filler with the sandwich structure comprises two conductive net layers and an iron powder layer arranged between the two net layers; wastewater treatment: adjusting the pH and temperature of the wastewater, then introducing the wastewater into a reactor, and using hydrogen generated by iron-carbon reaction as a signal source: when the hydrogen concentration is greater than 0.5%, automatically closing aeration to enter a denitrification mode, and when the hydrogen concentration is less than 0.2%, starting aeration to convert into a nitrification mode; the composite membrane formed in the reactor continuously degrades ammonia nitrogen, and deamination treatment is completed.