49 results about "Cortex Fraxini" patented technology

The invention discloses a traditional Chinese medicine effective component compound preparation for inhibiting colorectal cancer transformation, which is composed of palmatine, berberine, coptisine and aesculin, and the mass ratio of the palmatine to the berberine to the coptisine to the aesculin is 3: 3: 1: 3. The traditional Chinese medicine active ingredient compound preparation can be prepared into clinical common preparations including granules, capsules or oral liquid according to a conventional method. The traditional Chinese medicine effective component compound preparation disclosed by the invention is proved to be capable of inhibiting intestinal inflammation, improving the intestinal barrier function and remarkably inhibiting colorectal tumor in an inflammatory state by intervening a mouse DSS induced chronic colitis model and an AOM / DSS combined induced colitis and proctitis cancer transformation model.

The present invention discloses a traditional Chinese medicine composition for treating dry eye and a preparation method thereof. The traditional Chinese medicine composition for treating dry eye is made from the following components in parts by weight: 10-12 parts of Chinese wolfberry, 5-10 parts of chrysanthemum, 10-15 parts of cassia seed, 10-12 parts of cortex fraxini, 5-10 parts of safflower, and 10-12 parts of phellodendron amurense. The traditional Chinese medicine composition for treating dry eye prepared by this method has less dosage, is convenient to use, safe and without side effects when treating dry eye, and has a significant therapeutic effect in aspects such as prolonging the breakup of the tear film, increasing the tear flow rate, and improving corneal staining, and can be promoted as a drug for treating dry eye.

The invention belongs to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine compound composition for treating ulcerative colitis and a preparation method thereof. Chinese pulsatilla root and coptis chinensis are used for clearing away heat and toxic materials, cooling blood and stopping dysentery; bletilla striata has the effects of astringing to stop bleeding, diminishing swelling and promoting granulation, fried sanguisorba officinalis has the effects of cooling blood, stopping bleeding, detoxifying and astringing sores, golden cypress has the effects of clearing heat and drying dampness, and ash bark has the effects of inducing astringency and stopping dysentery, all serve as ministerial drugs, assist the monarch drugs to play roles, enhance the curative effects of the monarch drugs and assist the monarch drugs in purging fire and detoxifying. The fried radix paeoniae alba is used for regulating menstruation and relieving pain, the root of Chinese toona astringents and stopping bleeding, and the radix scutellariae is used for clearing away heat and toxic materials, which are all adjuvant drugs. The liquorice serves as a conductant drug and can relieve spasm and pain and resolve the drugs. All the traditional Chinese medicine components are in synergistic interaction, so that the traditional Chinese medicine compound composition has the effects of clearing away heat and toxic materials, astringing intestines and stopping bleeding, and astringing sores and promoting tissue regeneration, and can be used for treating ulcerative colitis.

The invention relates to a fermented traditional Chinese medicine composition for preventing and treating piglet viral diarrhea as well as a preparation method and application thereof, and relates to the technical field of livestock breeding. The feed is prepared by taking traditional Chinese medicine components as basic raw materials and adding probiotics for fermentation, and the traditional Chinese medicine components comprise the following raw materials in parts by weight: 0.5-1.5 parts of cardamine violifolia dry powder, 5-15 parts of Chinese pulsatilla root, 10-20 parts of coptis chinensis, 10-20 parts of golden cypress, 10-20 parts of ash bark, 4-8 parts of turmeric, 6-10 parts of pumpkin seeds and 4-8 parts of a ginkgo leaf extract feed additive. Through cooperation of multiple components, the immunity and antioxidant functions of the body are enhanced, the structural integrity of the intestinal tract is maintained, piglet diarrhea caused by PEDV infection is effectively relieved, and growth and development of the piglet are promoted; local specialty crops are selected as medicines, and theoretical basis and practical reference are provided for deep processing of local genuine medicinal materials and PED prevention and control.

The invention relates to the technical field of traditional Chinese medicine pharmacy, and discloses a traditional Chinese medicine composition for reducing uric acid and application thereof, and the traditional Chinese medicine composition comprises the following components in parts by mass: 15-20 parts of ash bark, 20-25 parts of clerodendranthus spicatus, 18-22 parts of astragalus membranaceus, 12-15 parts of prepared polygonum multiflorum, 15-18 parts of rhizoma smilacis glabrae, 8-10 parts of ligusticum wallichii, 10-12 parts of roasted rhizoma atractylodis macrocephalae and 10-15 parts of salt-fried semen plantaginis. The preparation method comprises the three steps of segmented extraction, sustained-release pellet forming and preparation forming. The traditional Chinese medicine composition disclosed by the invention has the high-efficiency performance of reducing uric acid, protecting healthy qi and achieving long-term effect, and can regulate and control a uric acid metabolic pathway in a multi-target manner; the product can be widely applied to the fields of products for treating primary hyperuricemia and gout in a sustained-release period, products for improving hyperuricemia metabolic syndrome, health-care tea for hyperuricemia and high-risk people, gel products for relieving red, swollen and heat pain of joints in an acute attack period of gout and the like, and the preparation process is controllable and easy to industrialize.

The invention relates to the technical field of preparation of feed additives, in particular to a traditional Chinese medicine compound feed additive for preventing stress syndromes of early weaned piglets and a preparation method of the traditional Chinese medicine compound feed additive. The medicine specifically comprises the following components: rhizoma osmundae, astragalus membranaceus, mangnolia officinalis, hawthorn, medicated leaven, pericarpium citri reticulatae, polygala tenuifolia, Chinese pulsatilla root, cortex fraxini, poria cocos, liquorice and spina date seed. The traditional Chinese medicine compound feed additive provided by the invention has a remarkable technical effect in the aspect of preventing the early-stage weaned piglet stress syndrome. Through scientific compatibility of various traditional Chinese medicine components, the additive can effectively improve the digestive function of the weaned piglets, enhance the immunity, relieve the stress response and remarkably reduce the diarrhea rate and the death rate. Experimental results show that piglets using the additive are superior to a blank control group and other substitution groups in the aspects of weight gain, oxidation resistance, serum hormone level, immune globulin indexes and the like, and the additive is proved to have a comprehensive physiological regulation function.

The invention discloses near-vision-preventing health-care liquid and a preparation method thereof. The near-vision-preventing health-care liquid is prepared from the following raw materials in parts by weight: 8-12 parts of cornu bubali, 1-3 parts of borneol, 4-6 parts of xanthophyll, 8-12 parts of radix angelicae sinensis, 8-12 parts of radix paeoniae rubra, 6-10 parts of folium mori, 12-18 parts of semen plantaginis, 8-12 parts of flos chrysanthemi, 12-18 parts of cortex fraxini and 12-18 parts of semen cassiae. According to years of medicine practicing experience and in combination with the theory of traditional Chinese medicine, natural traditional Chinese medicine plants with the effects of clearing liver and improving vision, clearing away heat and toxic materials, promoting blood circulation, dissipating blood stasis and relieving pain, clearing away heat and drying dampness and promoting blood circulation are selected; the traditional Chinese medicine composition can relieve eyestrain, eye dryness, eye acerbity, red eyes, blurred vision, dark circles, ghosting, photophobia, tear against wind, eye discomfort and other symptoms caused by overuse of eyes, the effect is remarkable, the effect taking speed is high, and myopia development is delayed by relieving eyestrain and preventing myopia; in addition, the preparation process is simple, easy to operate and convenient for expanded production.

The present application belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition for treating acute or chronic gouty arthritis, and a preparation method and application thereof. One of the purposes of the present application is to provide a traditional Chinese medicine composition comprising lotus leaf, cortex fraxini, atractylodes, smilax glabra, phellodendron, plantago seed and licorice. In the prescription, the lotus leaf is the monarch herb for clearing heat and resolving summer-heat, raising clear yang and cooling blood to stop bleeding; cortex fraxini, phellodendron and atractylodes are the ministerial herbs to strengthen the heat-clearing and dampness-drying effect of the monarch herb; plantago seed is diuretic and detoxicant, smilax glabra is detoxicant and dampness-removing and joint-activating, and licorice is heat-clearing and detoxicant and pain-relieving, which can not only relieve symptoms, but also has mild medicinal property. The whole prescription has the effects of removing dampness and discharging turbidity, removing blood stasis and heat, and relieving pain, and is effective in treating acute or chronic gouty arthritis with symptoms of joint redness and swelling, fever, pain or tenderness, and limited activity, or accompanied by systemic fever, thirst and yellowish urine.

The invention discloses an anti-enterocytozoon hepatopenaei traditional Chinese medicine compound and a preparation method and application thereof.The anti-enterocytozoon hepatopenaei traditional Chinese medicine compound is characterized by being prepared from, by weight, 10-20 parts of sophora alopecuroide alcohol extract, 50-75 parts of cortex fraxini alcohol extract and 10-30 parts of fructus evodiae alcohol extract.The preparation method comprises the following steps that dried and smashed sophora alopecuroide, cortex fraxini and fructus evodiae are weighed; respectively dissolving and extracting by using absolute ethyl alcohol to obtain alcohol extracts; the preparation method comprises the following steps: weighing the traditional Chinese medicine alcohol extract in parts by weight, uniformly mixing to obtain the anti-enterocytozoon hepatopenaei traditional Chinese medicine compound, and further provides application of the anti-enterocytozoon hepatopenaei traditional Chinese medicine compound, the sophora alopecuroide alcohol extract, the ash bark alcohol extract and the fructus evodiae alcohol extract in preparation of an enterocytozoon hepatopenaei inhibitor. The weight gain rate of prawns is increased, economic losses caused by outbreak of enterocytozoon hepatopenaei to prawn culture can be effectively reduced, and the compound is low in cost and simple in use method.

The application provides a traditional Chinese medicine composition and application thereof in preparation of a drug for treating reflux esophagitis, and relates to the technical field of traditional Chinese medicine pharmacy.The traditional Chinese medicine composition takes Fritillaria thunbergii Miq., Evodia rutaecarpa, Citrus medica L. as monarch drugs, Inula japonica, Terminalia chebula Retz., Nardostachys chinensis, Syzygium aromaticum, Amomum subulatum, Phoenix tree as minister drugs, mother-of-pearl, Cortex Fraxini, Gentiana scabra Bunge, Osmanthus fragrans as auxiliary drugs, and Glycyrrhiza uralensis as a servant drug, and the drugs are combined to have the effects of dispersing the liver and harmonizing the stomach, reducing adverse and acid, and regulating cold and heat.The traditional Chinese medicine composition can significantly improve the esophagitis index of RE rats, has obvious inhibitory effect on inflammatory damage, can significantly improve the pathological morphology of the esophageal tissue of the RE rats, and realizes better anti-inflammatory and therapeutic effect on the RE rats.Meanwhile, the traditional Chinese medicine composition can significantly improve and alleviate the clinical symptoms of the patients with reflux esophagitis, such as acid reflux, heartburn, abdominal distension and belching, and reduce the frequency of the clinical symptoms.The traditional Chinese medicine composition is expected to be further developed and popularized as a drug for treating reflux esophagitis.

The invention discloses a traditional Chinese medicine composition, which is prepared from the following raw materials: cortex fraxini, herba portulacae, artemisia rupestris, duckweed, rhizoma atractylodis macrocephalae, poria cocos and liquorice in a weight ratio of (15-20): (15-20): (15-20): (15-20): (7-12): (7-12): 10, and the traditional Chinese medicine composition is a mixture obtained by mixing screen underflow obtained after the medicinal materials are crushed and sieved by a 80-mesh sieve. The traditional Chinese medicine composition can improve the average daily gain of heat stress poultry animals; the feed conversion ratio of heat stress poultry animals is reduced; the body temperature of the heat stress poultry animals is reduced; the respiratory rate of heat stress poultry animals is reduced; treating or alleviating intestinal injury of heat stress poultry animals; the content of IL-10 in serum of poultry animals is increased; and the content of IL-1beta, IL-6 and TNF-alpha in serum of poultry animals can be reduced. The traditional Chinese medicine composition has an application prospect.

The invention discloses a pharmaceutical composition for treating diarrhea of yak calves, and relates to the technical field of biological pharmacy, the pharmaceutical composition is prepared from the following raw materials: coptis chinensis, cortex phellodendri, cortex fraxini, Chinese pulsatilla root, purslane, Chinese yam, poria cocos, bighead atractylodes rhizome and liquorice, various natural traditional Chinese medicinal materials are adopted as the raw materials, and the pharmaceutical composition is safe and free of side effects; and adverse effects on the meat quality of the yak calves and the quality of dairy products are avoided. The invention also discloses a preparation method of the pharmaceutical composition for treating diarrhea of yak calves. The preparation method comprises the following steps: step 1, weighing raw materials; 2, pretreating the raw materials; step 3, adding water for soaking; step 4, first heating reflux extraction; step 5, filtering for the first time; step 6, adding water for the second time and extracting; step 7, filtering for the second time; step 8, concentration treatment; the preparation method is easy to operate, effective components in the raw materials can be extracted to the maximum extent through reasonable extraction and concentration processes, and the curative effect of the pharmaceutical composition is improved.

The invention belongs to the technical field of detection of active ingredients of viola tianshanica, and particularly relates to construction and application of an electrochemical test strip for simultaneous electrochemical detection of aesculetin and quercetin. Ti3C2Tx MXene (at) MWCNTs / SPE is prepared and represented, feasibility analysis is carried out on the Ti3C2Tx MXene (at) MWCNTs / SPE through an electrochemical method, and aesculetin and quercetin are both in an adsorption control process and a double-proton and double-electron quasi-reversible process on the surface of an electrode. The two compounds have good electrochemical activity in a PBS (Phosphate Buffer Solution) with the pH value of 3, the optimal scanning potential interval is 0.1-0.7 V, and the concentration and Ipa are in a good linear relationship. The method disclosed by the invention has good sensitivity, reproducibility and anti-interference performance, the content detection of aesculetin and quercetin can be realized at the same time, and the electrochemical sensor plays an important role in evaluating the quality of traditional Chinese medicinal materials.

The present invention provides a traditional Chinese medicine composition for herpes zoster oticus and its application, which relates to the technical field of traditional Chinese medicine pharmacy. The traditional Chinese medicine composition is obtained by reasonable compatibility in accordance with the principle of syndrome differentiation and treatment of traditional Chinese medicine, and is composed of Scorzonera austriaca, Cimicifuga foetida, Cortex Fraxini, Arisaema heterophyllum, Abutilon theophrasti, Aucklandia lappa, Chrysanthemum indicum, Houttuynia cordata, Cynanchum atratum, and Ginger Peel. The compatibility of various herbs is reasonable, and it has the effects of clearing heat and detoxifying, promoting qi circulation to relieve pain, detumescing and treating sores, and promoting diuresis to reduce swelling. It has good curative effect, short course of treatment, and no toxic and side effects. The traditional Chinese medicine composition of the present invention has a significant improvement effect on the spontaneous pain behavior of rats with postherpetic neuralgia model and aspects such as the levels of serum IL-2, IL-6, and TNF-α, achieving the simultaneous treatment of the symptoms and root causes of herpes zoster oticus. The traditional Chinese medicine composition of the present invention has a significant therapeutic effect on herpes zoster oticus, has a high effective rate, can quickly relieve the clinical symptoms of patients, shorten the recovery time of patients, and relieve the pain of patients.

The invention provides a Chinese pulsatilla root oral liquid preparation and a preparation method thereof.The Chinese pulsatilla root oral liquid preparation per liter comprises 300 g of Chinese pulsatilla roots, 150 g of rhizoma coptidis, 300 g of cortex fraxini, 225 g of cortex phellodendri, 50 ml of PEG-400, 20 g of xanthan gum, 20 g of hydrophilic colloidal silicon dioxide, 5 g of neotame, 1.5 g of ethylparaben and the balance auxiliary materials. The palatability is better, and the clinical effect is obviously improved compared with that of other similar products.

The invention relates to a preparation method of a cortex fraxini and wormwood composition. The preparation method comprises the following steps: mixing sterilized cortex fraxini powder with an aqueous solution containing zymophyte and biological enzyme, fermenting and performing enzymolysis; adding water for extraction, filtering, concentrating under reduced pressure, centrifuging, taking supernate, enabling the supernate to pass through a polyamide resin column, firstly eluting with water, then eluting with 10%-30% ethanol, finally eluting with 70%-90% ethanol, collecting eluent, and concentrating under reduced pressure until the eluent is dry, so as to obtain a cortex fraxini lignan component extract; adding DES with the water content of 10%-30% and cellulase with the water content of 2%-5% into the wormwood powder, extracting, filtering, concentrating filtrate under reduced pressure, centrifuging, taking supernate, passing through a medium pressure to prepare chromatography, eluting with 30%-50% ethanol, collecting eluent, and concentrating under reduced pressure until the eluent is dry, so as to obtain wormwood chlorogenic acid component extract; the cortex fraxini and wormwood composition is a mixture of cortex fraxini lignan component extract and / or wormwood chlorogenic acid component extract. The cortex fraxini and wormwood composition has antibacterial, anti-inflammatory and anti-allergic effects and can be widely applied to prevention and treatment of acne.

The invention relates to a traditional Chinese medicine composition for treating blurred vision and muscae volitantes and a preparation method thereof. The invention belongs to the technical field of traditional Chinese medicines, and is helpful for relieving symptoms such as blurred vision and muscae volitantes. The formula comprises the following components: fructus lycii, flos chrysanthemi, herba taraxaci, radix ophiopogonis, pericarpium citri reticulatae fried with honey and bran, cortex fraxini, semen cuscutae, dendrobium officinale, soft talc, rhizoma coptidis, radix cynanchi paniculati, radix scutellariae, fried semen cassiae, fried fructus viticis, radix rehmanniae praeparata, prepared fructus corni, cortex moutan, rhizoma dioscoreae with honey and bran, white poria, rhizoma alismatis and bear gall, wherein the fructus lycii, the flos chrysanthemi, the herba taraxaci, the cortex fraxini, the semen cuscutae and the fried fructus viticis have the effects of clearing away heat and toxic materials, nourishing the liver and improving eyesight and the like; through the combined effect of various herbal medicine components, compared with similar products, the effect is better, and compared with western medicines, the Chinese herbal medicines reduce the potential safety hazard of medicine taking. The traditional Chinese medicine composition has the remarkable effects of clearing away heat and toxic materials, nourishing the liver, improving eyesight and relieving eye fatigue and blurred vision, muscae volitantes and other symptoms caused by overuse of eyes, and is safe and effective after being taken for a long time.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition, a preparation method thereof and application of the traditional Chinese medicine composition to preparation of medicine for treating ulcerative colitis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 27 to 33 parts of radix puerariae, 45 to 55 parts of acalypha australis, 13 to 17 parts of polygonatum kingianum, 27 to 33 parts of radix scutellariae, 27 to 33 parts of cortex fraxini, 40 to 50 parts of poria cocos, 27 to 33 parts of radix aucklandiae, 13 to 17 parts of fructus mume and 13 to 17 parts of liquorice root. The traditional Chinese medicine is used for treating ulcerative colitis according to the thinking of traditional Chinese medicine, and has the effects of clearing heat, eliminating dampness, regulating liver and spleen, regulating qi, harmonizing blood, astringing ulcer, promoting tissue regeneration, invigorating spleen, replenishing qi, tonifying kidney and consolidating basis in a remission period, so that the effect of treating ulcerative colitis is achieved. The traditional Chinese medicine composition disclosed by the invention is simple and efficient, the raw material medicines are economical and practical, the preparation and extraction method is simple, the cost is low, and the traditional Chinese medicine composition has universality and is easy for large-scale production, so that the traditional Chinese medicine composition has good practical application value.

The invention discloses a traditional Chinese medicinal material identification and collection device and method, and belongs to the technical field of traditional Chinese medicinal material identification. The identifying and collecting device for the traditional Chinese medicinal materials comprises a chassis, and a walking mechanism and a collecting mechanism which are respectively connected to the bottom and the upper surface of the chassis, and further comprises a pesticide spraying mechanism and an identifying mechanism which are fixedly connected to the chassis, and an ultraviolet lamp irradiation or sunlight irradiation atmosphere covering the upper parts of the traditional Chinese medicinal materials; the spraying mechanism sprays medicine to the surfaces of the traditional Chinese medicinal materials; the collection mechanism collects the fluorescent dominant traditional Chinese medicinal materials identified by the identification mechanism, and based on the fluorescent dominant mechanism of the traditional Chinese medicinal materials, through the cooperation of the collection mechanism and the identification mechanism, the problems of high cost and low efficiency required by identification of the cortex fraxini traditional Chinese medicinal materials in the prior art are solved.

The invention relates to the technical field of traditional Chinese medicine preparations, and provides veterinary traditional Chinese medicine oral liquid for preventing and treating poultry glandular and muscular gastritis and application of the veterinary traditional Chinese medicine oral liquid for preventing and treating the poultry glandular and muscular gastritis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 30 to 50 parts of rhizoma coptidis, 20 to 30 parts of cortex phellodendri, 40 to 50 parts of herba taraxaci, 20 to 30 parts of herba patriniae, 30 to 40 parts of radix astragali seu hedysari, 80 to 100 parts of cortex fraxini, 20 to 40 parts of rhizoma atractylodis, 50 to 70 parts of poria cocos, 10 to 30 parts of rhizoma alismatis, 20 to 40 parts of pericarpium citri reticulatae, 10 to 30 parts of fried medicated leaven, 20 to 30 parts of fried fructus crataegi, 10 to 30 parts of fried malt, 10 to 30 parts of radix angelicae sinensis, 20 to 30 parts of rhizoma cyperi, 10 to 30 parts of rhizoma curcumae and 10 to 20 parts of radix glycyrrhizae preparata. According to the technical scheme, the problems of reduced feed intake, slow growth and development, emaciation and the like of poultry caused by glandular ventriculitis in the prior art are solved.

The invention provides a construction method and application of a fingerprint spectrum of Hexishi chrysanthemum. The construction method comprises the following steps: a) preparation of reference substance solutions: taking aesculetin, scutellarin, apigenin and luteolin as reference substances, respectively adding solutions for dissolving to obtain the reference substance solutions, and the reference substance solutions comprise an aesculetin solution, a scutellarin solution, an apigenin solution and a luteolin solution; b) preparation of a test solution: mixing the powder of the Hexishi chrysanthemum with a methanol solution, carrying out heating reflux treatment, cooling, and filtering to obtain the test solution; and c) placing the test solution and the plurality of reference substance solutions in a high performance liquid chromatograph, and measuring to obtain a high performance liquid chromatogram of the test solution and high performance liquid chromatograms of the reference substance solutions. The method can solve the problem of lack of a method for controlling the quality of the Hexishi chrysanthemum in the prior art, and is suitable for the field of traditional Chinese medicine analysis.

The invention discloses a traditional Chinese medicine decoction and intestinal probiotic combined medicine for treating ulcerative colitis. The medicine is prepared by uniformly mixing traditional Chinese medicine decoction and intestinal probiotic liquid, the traditional Chinese medicine decoction is prepared by adding water into pulsatilla chinensis, cortex fraxini, coptis chinensis, radix sophorae flavescentis, hairyvein agrimony, pomegranate rind, purslane, sophora flower and sanguisorba officinalis, soaking at room temperature, decocting with strong fire, then slowly decocting with slow fire, and filtering. The intestinal probiotic liquid is one of clostridium butyricum liquid, lactobacillus plantarum liquid and lactobacillus reuteri liquid or a mixture of two or more than two of the clostridium butyricum liquid, the lactobacillus plantarum liquid and the lactobacillus reuteri liquid in equal volume. The traditional Chinese medicine is rich in raw materials, easy to produce and prepare, convenient to take and good in effect, provides a new medicine for treating ulcerative colitis, opens up a new way for treating ulcerative colitis, and has huge economic and social benefits.

The invention relates to the technical field of feed additives, in particular to a feed additive for preventing and treating diarrhea of livestock and poultry as well as a preparation method and application of the feed additive. The feed additive comprises 10-30 parts of traditional Chinese medicine dry paste powder and 70-90 parts of auxiliary materials, wherein the traditional Chinese medicine dry paste powder comprises a traditional Chinese medicine extract extracted from the following traditional Chinese medicine compositions in parts by weight: 5-15 parts of coptis chinensis, 8-15 parts of Chinese pulsatilla root, 3-8 parts of carbonized sanguisorba root, 5-12 parts of honeysuckle stem, 2-5 parts of corydalis tuber, 3-6 parts of elecampane, 5-10 parts of ash bark, 8-15 parts of humifuse euphorbia herb, 8-15 parts of Chinese yam, 8-15 parts of white hyacinth bean, 3-6 parts of fingered citron, 3-6 parts of fortune eupatorium herb and 3-6 parts of raw liquorice. According to the invention, the unique compatibility theory of traditional Chinese medicines is utilized to form a multi-component synergistic effect, pathogens are not easy to generate drug resistance, the residue is low, the safety is high, the requirements of current mainstream'antibiotic-free breeding 'can be met, diarrhea is prevented and treated through the multi-dimensional effects of checking diarrhea, regulating bacteria, protecting membranes, resisting inflammation and promoting digestion, and the feed has the dual advantages of disease prevention and treatment and green safety.

The application discloses a traditional Chinese medicine pair for treating radiation enteropathy and application thereof, and relates to the technical field of traditional Chinese medicine preparation. The traditional Chinese medicine pair comprises the following components in parts by weight: 2-20 parts of cortex fraxini and 2-20 parts of radix scrophulariae. The cortex fraxini has the effects of astringing and stopping dysentery, the radix scrophulariae has the effects of clearing heat and drying dampness, and the cortex fraxini and the radix scrophulariae have the effects of clearing heat and resolving toxins, invigorating the spleen and removing dampness, and astringing intestines and stopping dysentery, and have the effect of treating radiation enteropathy. The application solves the problem that effective drugs for treating radiation enteropathy are lacked in the prior art.

The invention discloses a preparation method of colon powder for external use, and relates to the technical field of medicine preparation. The colon powder for external use is prepared from the following raw materials in parts by weight: 15 to 25 parts of radix astragali seu hedysari, 10 to 20 parts of radix pulsatillae, 8 to 18 parts of radix astragali seu hedysari, 6 to 16 parts of radix arnebiae seu lithospermi and 3 to 8 parts of auxiliary materials. The preparation method comprises the steps of raw material pretreatment, extraction, drying, mixing and sterilization. The raw materials also comprise the following components in parts by weight: 5-15 parts of purslane and 4-12 parts of cortex fraxini, and the weight ratio of the purslane to the cortex fraxini is 1: (0.8-1.2). According to the present invention, the radix astragali seu hedysari, the Chinese pulsatilla root, the radix astragali seu hedysari and the laver are adopted as the raw materials, the radix astragali seu hedysari has effects of spleen strengthening and qi supplementing, the Chinese pulsatilla root has effects of heat clearing and detoxification, the radix astragali seu hedysari has effects of immunity enhancing, and the radix arnebiae seu lithospermi has effects of blood cooling and blood activating so as to achieve multiple effects of inflammation resistance, colonic the treatment of ulcerative colitis and other diseases is remarkably improved, and the problems that an existing formula is single and the curative effect is limited are solved.

The present application relates to a preparation method and application of Cortex Fraxini extract with pine wood nematode killing activity, wherein dry powder of Cortex Fraxini is extracted by ethanol to obtain an extract solution, and the ethanol extract obtained after reduced pressure distillation is extracted by ethyl acetate-water liquid-liquid extraction, the ethyl acetate phase is reduced pressure distilled to obtain the ethyl acetate extract of Cortex Fraxini with strong pine wood nematode killing activity, and the main active ingredient of the extract, aesculin, is separated therefrom. The corrected mortality rate of the ethyl acetate extract of Cortex Fraxini to pine wood nematode is as high as 94.14% at a concentration of 1 mg / mL within 72 h; and the half lethal concentration of aesculin to pine wood nematode is 30.37 μg / mL. The present application develops a new use of Cortex Fraxini extract, and provides an effective plant-derived pine wood nematode killing active substance, the raw material source is convenient, the extraction method is simple, the cost is low, the Cortex Fraxini extract has development potential in controlling pine wood nematode disease, and is applied to the development of an environmentally friendly plant-derived pine wood nematode killing agent.

The application provides a separation and purification method of aesculin, aesculetin and aesculin in cortex fraxini, which comprises the following steps: firstly, heating extraction is performed on the crushed cortex fraxini raw material; secondly, plate and frame pressure filtration is performed on the obtained extract, and the filtrate is subjected to chromatographic separation on a macroporous resin column; then, 10-30% ethanol is used for resolving the macroporous resin column and purifying aesculin; subsequently, 50-80% ethanol is used for resolving the macroporous resin column, and the resolving liquid is subjected to enzymolysis and aesculetin purification; finally, the enzymolysis mother liquor is treated and aesculin is purified. The multi-layer separation and purification scheme can simultaneously and efficiently separate and purify the three high-value active components of aesculin, aesculetin and aesculin in cortex fraxini, greatly improves the comprehensive utilization rate of cortex fraxini resources, creates higher product value, reduces the use amount of organic solvents, reduces the production cost, reduces the pollution to the environment, and meets the green and environmental protection production concept.

The application discloses a traditional Chinese medicine composition for preventing and treating the mandarinfish frog iridovirus disease, and belongs to the technical field of aquatic animal disease prevention and treatment, which is prepared from the following raw materials in corresponding weight parts: 40-45 parts of radix isatidis, 10-15 parts of rhizoma coptidis, 5-8 parts of acanthopanax, 3-7 parts of cortex fraxini, and 15-20 parts of radix scrophulariae. The traditional Chinese medicine composition has the advantages of simple and reasonable component combination, high cure efficiency, and green, non-toxic and non-side effect, and can effectively inhibit the iridovirus by interfering with the adsorption of the iridovirus to host cells, preventing the virus from penetrating into cells, and inhibiting the replication and synthesis of the virus in the host cells.

The present invention discloses a Tibetan medicine composition for treating chronic obstructive pneumonia, its preparation method and application. The Tibetan medicine composition is obtained by repeatedly optimizing the drug composition and content through clinical and basic research, and is made of seven medicinal materials including Gentiana scabra Bunge flower, Cortex Fraxini, Lagotis glauca, Myristica fragrans Houtt., Glycyrrhiza uralensis Fisch., Concretio Silicea Bambusae, and Zhaxun ointment. The Tibetan medicine composition of the present invention can reduce the expression levels of inflammatory factors in the serum and lung tissues of mice with chronic obstructive pneumonia efficacy models and improve lung function indicators, induce autophagy by activating the AMPK / mTOR pathway to reduce airway inflammation, and reduce the expression of inflammatory proteins by inhibiting the activation of MAPK pathway proteins. This formula is clinically applicable to the treatment of chronic obstructive pulmonary disease, is safe, effective, and quality controllable, and has better curative effects than chemical drugs such as glucocorticoids already on the market, and is a national medicine variety urgently needed in clinical practice.

The invention relates to a traditional Chinese medicine composition for clearing away heat and toxic materials and cooling blood, a preparation method and application and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine composition for clearing away heat and toxic materials and cooling blood comprises coptis chinensis, pulsatilla chinensis, cortex fraxini, Chinese yam, semen coicis, liquorice, codonopsis pilosula, poria cocos, plantain herb and the like, can be used for treating snake wounds, and effectively relieves snake venom symptoms and promotes body recovery through multiple effects of clearing away heat and toxic materials, relieving swelling and pain and strengthening body resistance to eliminate pathogenic factors; the traditional Chinese medicine can also be used for relieving insomnia and skin allergy symptoms, and has very good curative effects.