3 results about "Cortex Fraxini" patented technology

The application provides a separation and purification method of aesculin, aesculetin and aesculin in cortex fraxini, which comprises the following steps: firstly, heating extraction is performed on the crushed cortex fraxini raw material; secondly, plate and frame pressure filtration is performed on the obtained extract, and the filtrate is subjected to chromatographic separation on a macroporous resin column; then, 10-30% ethanol is used for resolving the macroporous resin column and purifying aesculin; subsequently, 50-80% ethanol is used for resolving the macroporous resin column, and the resolving liquid is subjected to enzymolysis and aesculetin purification; finally, the enzymolysis mother liquor is treated and aesculin is purified. The multi-layer separation and purification scheme can simultaneously and efficiently separate and purify the three high-value active components of aesculin, aesculetin and aesculin in cortex fraxini, greatly improves the comprehensive utilization rate of cortex fraxini resources, creates higher product value, reduces the use amount of organic solvents, reduces the production cost, reduces the pollution to the environment, and meets the green and environmental protection production concept.

The application discloses a traditional Chinese medicine composition for preventing and treating the mandarinfish frog iridovirus disease, and belongs to the technical field of aquatic animal disease prevention and treatment, which is prepared from the following raw materials in corresponding weight parts: 40-45 parts of radix isatidis, 10-15 parts of rhizoma coptidis, 5-8 parts of acanthopanax, 3-7 parts of cortex fraxini, and 15-20 parts of radix scrophulariae. The traditional Chinese medicine composition has the advantages of simple and reasonable component combination, high cure efficiency, and green, non-toxic and non-side effect, and can effectively inhibit the iridovirus by interfering with the adsorption of the iridovirus to host cells, preventing the virus from penetrating into cells, and inhibiting the replication and synthesis of the virus in the host cells.

The application discloses application of a traditional Chinese medicine composition in preparation of a medicine for treating rheumatoid arthritis, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw medicinal materials in parts by weight: 20-60 parts of smilax glabra, 10-20 parts of achyranthes bidentata, 15-30 parts of radix paeoniae alba, 10-30 parts of giant knotweed, 6-20 parts of cortex fraxini, 3-10 parts of rhizoma coptidis, 6-20 parts of phellodendri chinensis, 10-30 parts of lily, and 6-20 parts of radix tinosporae. The traditional Chinese medicine composition can significantly improve the joint redness and swelling of a rheumatoid arthritis model animal, reduce an arthritis index, inhibit systemic and local joint inflammatory reactions, reduce synovial membrane proliferation, cartilage erosion and bone destruction, and is safe in use, thereby providing a safe and effective new scheme for clinical treatment of rheumatoid arthritis.