7 results about "Cortex Fraxini" patented technology

The application provides a traditional Chinese medicine composition and application thereof in preparation of a drug for treating reflux esophagitis, and relates to the technical field of traditional Chinese medicine pharmacy.The traditional Chinese medicine composition takes Fritillaria thunbergii Miq., Evodia rutaecarpa, Citrus medica L. as monarch drugs, Inula japonica, Terminalia chebula Retz., Nardostachys chinensis, Syzygium aromaticum, Amomum subulatum, Phoenix tree as minister drugs, mother-of-pearl, Cortex Fraxini, Gentiana scabra Bunge, Osmanthus fragrans as auxiliary drugs, and Glycyrrhiza uralensis as a servant drug, and the drugs are combined to have the effects of dispersing the liver and harmonizing the stomach, reducing adverse and acid, and regulating cold and heat.The traditional Chinese medicine composition can significantly improve the esophagitis index of RE rats, has obvious inhibitory effect on inflammatory damage, can significantly improve the pathological morphology of the esophageal tissue of the RE rats, and realizes better anti-inflammatory and therapeutic effect on the RE rats.Meanwhile, the traditional Chinese medicine composition can significantly improve and alleviate the clinical symptoms of the patients with reflux esophagitis, such as acid reflux, heartburn, abdominal distension and belching, and reduce the frequency of the clinical symptoms.The traditional Chinese medicine composition is expected to be further developed and popularized as a drug for treating reflux esophagitis.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition, a preparation method thereof and application of the traditional Chinese medicine composition to preparation of medicine for treating ulcerative colitis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 27 to 33 parts of radix puerariae, 45 to 55 parts of acalypha australis, 13 to 17 parts of polygonatum kingianum, 27 to 33 parts of radix scutellariae, 27 to 33 parts of cortex fraxini, 40 to 50 parts of poria cocos, 27 to 33 parts of radix aucklandiae, 13 to 17 parts of fructus mume and 13 to 17 parts of liquorice root. The traditional Chinese medicine is used for treating ulcerative colitis according to the thinking of traditional Chinese medicine, and has the effects of clearing heat, eliminating dampness, regulating liver and spleen, regulating qi, harmonizing blood, astringing ulcer, promoting tissue regeneration, invigorating spleen, replenishing qi, tonifying kidney and consolidating basis in a remission period, so that the effect of treating ulcerative colitis is achieved. The traditional Chinese medicine composition disclosed by the invention is simple and efficient, the raw material medicines are economical and practical, the preparation and extraction method is simple, the cost is low, and the traditional Chinese medicine composition has universality and is easy for large-scale production, so that the traditional Chinese medicine composition has good practical application value.

The application provides a separation and purification method of aesculin, aesculetin and aesculin in cortex fraxini, which comprises the following steps: firstly, heating extraction is performed on the crushed cortex fraxini raw material; secondly, plate and frame pressure filtration is performed on the obtained extract, and the filtrate is subjected to chromatographic separation on a macroporous resin column; then, 10-30% ethanol is used for resolving the macroporous resin column and purifying aesculin; subsequently, 50-80% ethanol is used for resolving the macroporous resin column, and the resolving liquid is subjected to enzymolysis and aesculetin purification; finally, the enzymolysis mother liquor is treated and aesculin is purified. The multi-layer separation and purification scheme can simultaneously and efficiently separate and purify the three high-value active components of aesculin, aesculetin and aesculin in cortex fraxini, greatly improves the comprehensive utilization rate of cortex fraxini resources, creates higher product value, reduces the use amount of organic solvents, reduces the production cost, reduces the pollution to the environment, and meets the green and environmental protection production concept.

The application discloses a traditional Chinese medicine composition for preventing and treating the mandarinfish frog iridovirus disease, and belongs to the technical field of aquatic animal disease prevention and treatment, which is prepared from the following raw materials in corresponding weight parts: 40-45 parts of radix isatidis, 10-15 parts of rhizoma coptidis, 5-8 parts of acanthopanax, 3-7 parts of cortex fraxini, and 15-20 parts of radix scrophulariae. The traditional Chinese medicine composition has the advantages of simple and reasonable component combination, high cure efficiency, and green, non-toxic and non-side effect, and can effectively inhibit the iridovirus by interfering with the adsorption of the iridovirus to host cells, preventing the virus from penetrating into cells, and inhibiting the replication and synthesis of the virus in the host cells.

The invention discloses a traditional Chinese medicine composition for treating skin inflammation as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 5 to 30 parts of snake slough, 5 to 30 parts of cortex dictamni, 10 to 50 parts of fructus mume, 5 to 30 parts of cortex fraxini, 5 to 30 parts of radix arnebiae seu lithospermi, 10 to 40 parts of radix isatidis, 10 to 40 parts of rhizoma anemarrhenae, 10 to 40 parts of gypsum and 5 to 30 parts of folium isatidis. The traditional Chinese medicine composition can effectively inhibit pruritus and inflammatory response caused by various dermatitis including neurodermatitis, accelerate tissue repair and healing processes of burn and scald parts, promote fading of red and swollen parts caused by mosquito bites, relieve local edema and discomfort and promote body function recovery.

The application discloses application of a traditional Chinese medicine composition in preparation of a medicine for treating rheumatoid arthritis, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw medicinal materials in parts by weight: 20-60 parts of smilax glabra, 10-20 parts of achyranthes bidentata, 15-30 parts of radix paeoniae alba, 10-30 parts of giant knotweed, 6-20 parts of cortex fraxini, 3-10 parts of rhizoma coptidis, 6-20 parts of phellodendri chinensis, 10-30 parts of lily, and 6-20 parts of radix tinosporae. The traditional Chinese medicine composition can significantly improve the joint redness and swelling of a rheumatoid arthritis model animal, reduce an arthritis index, inhibit systemic and local joint inflammatory reactions, reduce synovial membrane proliferation, cartilage erosion and bone destruction, and is safe in use, thereby providing a safe and effective new scheme for clinical treatment of rheumatoid arthritis.

The invention belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating gout, a preparation method and application. The traditional Chinese medicine composition comprises 15-20 parts of yam rhizome, 12-15 parts of radix clematidis, 15-20 parts of cortex fraxini, 20-25 parts of Chinese starjasmine stem, 18-20 parts of pyrrosia lingua, 10-15 parts of herba lycopi, 15-18 parts of motherwort, 10-12 parts of endothelium corneum gigeriae galli, 3-6 parts of edible tulip, 10-15 parts of lily, 12-15 parts of hovenia dulcis thunb, 8-10 parts of spina gleditsiae, 10-15 parts of fructus liquidambaris and 8-10 parts of radix puerariae. The medicines in the whole formula are compatible to jointly achieve the effects of clearing damp and expelling turbidity, promoting blood circulation to remove meridian obstruction, clearing heat and diminishing swelling, and softening hard mass and eliminating stone, take care of healthy qi, adapt to symptoms of intermingled dampness and blood stasis, or combined dampness and heat or combined formation of tophus in the acute / remission period of gout, regulate inducements such as drinking, weakness of spleen and stomach and the like and combined symptoms, and are rigorous in compatibility and clear in primary and secondary effects.