62 results about "Evodia rutaecarpa" patented technology

The invention relates to the technical field of formula optimization, and discloses a Qi king liquid formula optimization method and system based on big data analysis, and the method comprises the steps: obtaining basic attribute data and compatibility relation data of traditional Chinese medicinal materials; constructing a medicine taste associated map, extracting a map embedding vector, splicing the vector with the medicine dosage information, and generating a state expression of the current formula; calculating a main efficiency reward item; when the medicinal material combination in the formula triggers the compatibility rule, calculating a compatibility constraint penalty term; calculating a reward signal; identifying monarch, minister, assistant and guide roles of the medicinal materials, generating role masks, limiting dosage adjustment ranges of the medicinal materials of different roles, and updating a task specific strategy according to an award signal; updating meta parameters of the meta learner based on the reward signals of the plurality of tasks; and repeating internal and external circulation until the convergence condition is met, and outputting the Qi liquid formula with the highest accumulated reward. According to the method, a comprehensive evaluation function capable of simultaneously evaluating the curative effect and accurately representing various incompatibility risks is constructed, so that the optimization result of the Qi king liquid formula is better.

This invention relates to the field of external moxibustion devices in traditional Chinese medicine, and in particular to a moxa stick for clearing dampness using the thunder-fire method, and its preparation method. The moxa stick comprises moxa wool, compound Chinese herbal powder, and moxa leaf paper; the compound Chinese herbal powder includes principal, assistant, adjuvant, and guiding herbs; the principal herbs include Evodia rutaecarpa, Cinnamomum cassia, and Ligusticum chuanxiong; the assistant herbs include stir-fried Atractylodes lancea, Poria cocos, Polyporus umbellatus, Alisma plantago-aquatica, stir-fried Atractylodes macrocephala, Astragalus membranaceus, and Amomum villosum; the adjuvant herbs include stir-fried Phellodendron chinense, Sophora flavescens, Artemisia capillaris, Gardenia jasminoides, Akebia quinata, Pinellia ternata, Centella asiatica, and Rosa laevigata root; the guiding herbs include Angelica dahurica, Pogostemon cablin, Angelica sinensis, Paeonia lactiflora, Glycyrrhiza uralensis, and Nelumbo nucifera leaf. This invention, guided by compound formulation theory, material innovation, process optimization, and packaging design, provides a thunder-fire moxa stick with strong targeted dampness-clearing properties, stable combustion performance, safety, portability, and controllable quality, showing promising application prospects.

The invention relates to the technical field of traditional Chinese medicine preparations, and provides a traditional Chinese medicine composition with acid inhibiting and esophagus protecting effects, which is prepared by compatibility of the following raw material medicines in parts by weight: 6-12 parts of coptis chinensis; 2 to 6 parts of fructus evodiae; 15 to 25 parts of cuttlebone; 10 to 20 parts of inula flower; 15 to 25 parts of ruddle; 12-20 parts of radix paeoniae alba; 8-15 parts of dried orange peel; and 6-10 parts of licorice root. According to the traditional Chinese medicine composition disclosed by the invention, through synergistic compatibility of multiple raw material medicines, the comprehensive efficacy of inhibiting acid, protecting mucous membranes and regulating power is realized, related symptoms are mildly relieved, no adverse reaction exists, and the traditional Chinese medicine composition is suitable for long-term conditioning. The standardized preparation process improves the extraction rate of effective components, ensures the stable and consistent curative effect of the product, overcomes the problems of extensive process and unstable quality of the traditional Chinese medicine preparation, and is suitable for different people, convenient to take, high in compliance, easily available in raw materials, controllable in cost and suitable for industrial production and clinical popularization.

This invention discloses a method for processing four-stage Coptis chinensis slices, its fingerprint spectrum, and its applications. The processing method includes two steps: preparation of excipients and processing. First, ginger juice, Evodia rutaecarpa juice, and licorice juice are prepared and mixed with rice wine in equal proportions to form a mixed medicinal juice. Then, the cleaned Coptis chinensis slices are mixed with the mixed medicinal juice and absorbed completely. After fermentation at 5℃-15℃ for 5-6 days, steaming for 1-2 hours, and drying at 70℃, the final product is obtained. This method is stable and feasible, and can significantly increase the content of alkaloid active ingredients in the slices. It also provides a method for establishing a fingerprint spectrum of the four-stage Coptis chinensis slices prepared by the above processing method. The fingerprint spectrum has been verified by precision, stability, and repeatability tests, showing high reliability. It can be used for quality evaluation of four-stage Coptis chinensis slices and for identification with Coptis chinensis slices processed using other methods. This invention constructs an integrated "processing-quality control" system, providing a scientific basis for standardized production, quality supervision, and standardized clinical application.

The present application belongs to the field of dandruff removal, and particularly relates to a dandruff removal composition, a preparation method and application thereof. The raw materials of the dandruff removal composition include a dandruff removal component and auxiliary materials, the raw materials of the dandruff removal component are Schisandra chinensis and Evodia rutaecarpa, and the auxiliary materials include phase A, phase B, phase C and phase E, phase A is selected from water and sodium laureth sulfate, phase B is selected from one or two of glycerol and polyquaternium, phase C is selected from one or more of sodium cocamphopropionate, sodium chloride, disodium EDTA, cocamide MEA, phenoxyethanol, ethylhexylglycerin, PEG-7, glyceryl cocoate and panthenol, and phase E is selected from one or more of citric acid, sodium chloride and water. It is found through repeated test research that Schisandra chinensis and Evodia rutaecarpa used in the dandruff removal component of the present application can synergistically promote the reduction of the number of dandruff of subjects with dandruff problems, not only achieving a good anti-dandruff effect, but also significantly inhibiting scalp itching.

The present application relates to the field of traditional Chinese medicine, and specifically relates to a kind of external use traditional Chinese medicine composition for treating thin endometrium, which is composed of the following raw medicinal materials: cinnamon 250-300g, fennel 250-300g, Corydalis 250-480g, Cnidium 250-400g, safflower 250-300g, Evodia 150-200g, mugwort leaf 250-300g, and ginger juice 500-600ml.The external use combined medicine of the present application can obviously improve the symptoms of dysmenorrhea, little menstrual flow, dark red menstrual color, and more menstrual blood clots, thicken the endometrial thickness during ovulation, and improve the clinical pregnancy rate of patients with thin endometrium.The external use traditional Chinese medicine is absorbed through skin, does not burden liver and kidney functions, achieves the purposes of warming meridians, activating blood and resolving stasis through the action of acupoint meridian, has little side effects, and is convenient for promotion.

The invention relates to the technical field of traditional Chinese medicine preparation. The invention provides a dripping pill containing radix angelicae sinensis, fructus corni and ginger as well as a preparation method and a quality detection method of the dripping pill. The dripping pill is prepared from the following raw materials in parts by weight: 10 to 20 parts of xanthoceras sorbifolia bunge, 10 to 20 parts of semen ziziphi spinosae, 8 to 15 parts of rhizoma chuanxiong, 8 to 15 parts of radix angelicae sinensis, 5 to 10 parts of rhizoma zingiberis and 5 to 10 parts of fructus evodiae. According to the preparation process of the dripping pill for cornus officinalis, provided by the invention, the extraction mode, the extraction solvent and the extraction time of the medicinal materials, dripping parameters of the dripping pill and the like are determined, so that effective components in the medicinal materials can be better extracted, and the purity, the dissolution rate and the extraction rate of the effective components are improved; the utilization rate of the medicinal materials and the absorption rate of effective components in the medicinal materials are improved; the prepared dropping pill is round and neat in appearance, moderate in hardness and not easy to adhere.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine composition for treating salivation of Parkinson's disease as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following raw materials: rhizoma pinellinae praeparata, trichosanthes kirilowii maxim, coptis chinensis, fructus evodiae, fructus aurantii immaturus, inula flower, rhizoma zingiberis, vinegar schisandra chinensis and cuttlebone. According to the traditional Chinese medicine composition for treating the salivation of the Parkinson's disease, the nine medicinal materials are scientifically matched, all the medicinal materials perform respective functions and have a synergistic effect, single-prescription accurate treatment is achieved for the salivation symptom of the Parkinson's disease, and the salivation improvement effect is remarkable; meanwhile, the whole formula follows the compatibility principle of regulating cold and heat, toxic drugs are not used, the overall drug property is mild, the adverse reaction of gastrointestinal tracts easily caused when Parkinson's disease is treated by clinical Chinese and western medicines can be effectively reduced while the salivary treatment effect is achieved, the curative effect and the medication safety are considered, and the long-term medication requirement of Parkinson's disease patients is met.

This invention provides a traditional Chinese medicine composition for reflux esophagitis, relating to the field of traditional Chinese medicine pharmaceutical technology. The composition comprises rose, Lithospermum erythrorhizon, Sargentodoxa cuneata, Rabdosia rubescens, honeysuckle, licorice, Evodia rutaecarpa, pearl, Coix seed, and Salvia miltiorrhiza. This composition is obtained through rational combination based on the principles of traditional Chinese medicine syndrome differentiation and treatment, with synergistic effects among the various herbs. This invention's composition exhibits significant anti-inflammatory effects and demonstrates significant repair and improvement effects on damaged esophageal mucosa. It shows significant efficacy in treating reflux esophagitis, significantly improving the treatment effectiveness and cure rate, significantly alleviating patient discomfort and pain. This invention's composition is a pure traditional Chinese medicine preparation, with no toxic side effects and no drug resistance.

This invention provides a traditional Chinese medicine composition for treating chronic atrophic gastritis and its application, belonging to the field of traditional Chinese medicine technology. The traditional Chinese medicine composition for treating chronic atrophic gastritis provided by this invention is made from the following raw materials in parts by weight: 15-25 parts of Salvia miltiorrhiza, 8-16 parts of Curcuma zedoaria (processed with vinegar), 2-6 parts of Eupolyphaga sinensis, 10-20 parts of Codonopsis pilosula, 8-16 parts of Dendrobium nobile (dried), 5-15 parts of Pinellia ternata (processed), 1-5 parts of Evodia rutaecarpa (processed), and 1-5 parts of Coptis chinensis. It has the effects of promoting blood circulation and removing blood stasis, strengthening the spleen and replenishing qi, nourishing yin and benefiting the stomach, inhibiting bacteria and inflammation, and regulating immunity. It is suitable for chronic atrophic gastritis, especially those with gastric blood stasis combined with stomach yin deficiency or spleen and stomach weakness. It can significantly repair the gastric mucosa and reverse atrophic intestinal metaplasia, and is safe and reliable, providing a new traditional Chinese medicine treatment for chronic atrophic gastritis.

This invention discloses a topical traditional Chinese medicine powder for eliminating effusions in cavities and its preparation method, belonging to the technical field of topical traditional Chinese medicine preparations. The powder is composed of Angelica sinensis, frankincense, myrrh, dragon's blood, catechu, Notopterygium incisum, Angelica dahurica, Saposhnikovia divaricata, Daphne genkwa, Paeonia lactiflora, Evodia rutaecarpa, and cinnamon in a specific weight ratio, prepared into a dark reddish-brown powder through a purely physical crushing process. This powder is specifically designed to eliminate various types of effusions in cavities. It can effectively improve symptoms within 1-7 days after use. The formula strictly adheres to traditional Chinese medicine compatibility principles, with each component working synergistically. The topical application method avoids the gastrointestinal irritation and other adverse reactions that may occur with oral medications. The preparation process is simple and environmentally friendly, requiring no complex equipment or chemical processing steps, and retains the original activity of each herbal component, demonstrating significant practical value and promising prospects for promotion.

This invention provides the application of Evodia rutaecarpa root extract in the preparation of antifungal agents, belonging to the field of agricultural fungal control technology. The active ingredient of the Evodia rutaecarpa root extract is naturally derived and easily obtained; its unique chemical structure and novel mechanism of action effectively avoid the problem of pathogen resistance caused by the concentrated mechanisms of action of existing fungicides, filling the market gap for quinolone-based plant-derived pesticides. The Evodia rutaecarpa root extract exhibits a precise antifungal spectrum and significant inhibitory effect, showing obvious inhibitory activity against soil-borne and interplant-borne plant fungi that are serious threats in agricultural production, such as Phytophthora tobaccoii, Fusarium equisetifolium, Colletotrichum gloeosporioides, and Fusarium moniliforme.

The application provides a traditional Chinese medicine composition and application thereof in preparation of a drug for treating reflux esophagitis, and relates to the technical field of traditional Chinese medicine pharmacy.The traditional Chinese medicine composition takes Fritillaria thunbergii Miq., Evodia rutaecarpa, Citrus medica L. as monarch drugs, Inula japonica, Terminalia chebula Retz., Nardostachys chinensis, Syzygium aromaticum, Amomum subulatum, Phoenix tree as minister drugs, mother-of-pearl, Cortex Fraxini, Gentiana scabra Bunge, Osmanthus fragrans as auxiliary drugs, and Glycyrrhiza uralensis as a servant drug, and the drugs are combined to have the effects of dispersing the liver and harmonizing the stomach, reducing adverse and acid, and regulating cold and heat.The traditional Chinese medicine composition can significantly improve the esophagitis index of RE rats, has obvious inhibitory effect on inflammatory damage, can significantly improve the pathological morphology of the esophageal tissue of the RE rats, and realizes better anti-inflammatory and therapeutic effect on the RE rats.Meanwhile, the traditional Chinese medicine composition can significantly improve and alleviate the clinical symptoms of the patients with reflux esophagitis, such as acid reflux, heartburn, abdominal distension and belching, and reduce the frequency of the clinical symptoms.The traditional Chinese medicine composition is expected to be further developed and popularized as a drug for treating reflux esophagitis.

The invention relates to the technical field of traditional Chinese medicine, and particularly discloses a traditional Chinese medicine composition for treating different syndrome types of stomach diseases and a preparation method thereof.The traditional Chinese medicine composition is prepared from, by weight, 15-25 parts of fried szechwan chinaberry fruit, 8-12 parts of radix bupleuri and 15-35 parts of fried fructus perillae. The traditional Chinese medicine composition is prepared from 40-60 parts of trogopterus dung, 15-35 parts of herba patriniae, 8-12 parts of radix scutellariae, 15-25 parts of radix codonopsis, 30-50 parts of fructus jujubae, 15-25 parts of radix paeoniae alba, 15-25 parts of pericarpium citri reticulatae, 2-6 parts of radix et rhizoma rhei, 8-12 parts of radix glycyrrhizae preparata and 10-35 parts of herba agrimoniae. The traditional Chinese medicine further comprises 15-35 parts of cuttlebone, 3-5 parts of calcined concha arcae, 40-60 parts of trogopterus dung, 8-12 parts of roasted rhizoma atractylodis macrocephalae, 15-25 parts of poria cocos, 4-8 parts of Chinese prickly ash, 8-12 parts of fructus amomi, 8-12 parts of fructus amomi rotundus and 5-10 parts of fructus evodiae. A complementary treatment system is formed for the four clinical common syndromes of spleen and stomach qi deficiency and water dampness, cold-dampness and qi stagnation and cold-heat intermingling, liver-stomach disharmony, cold-heat intermingling type reflux disease and phlegm-blood stasis type gastric polyp respectively and accurately.

The invention provides an antibiotic substitute preparation based on plant essential oil and a preparation method and application thereof, and belongs to the field of animal feed additives. The preparation comprises the following components in parts by mass: 2-4 parts of fructus evodiae essential oil, 0.5-2 parts of citronella essential oil, 1-2 parts of pepper essential oil, 5-8 parts of clostridium butyricum powder, 3-5 parts of xylooligosaccharide, 8-12 parts of beta-cyclodextrin, 2-3 parts of chitosan, 1-2 parts of poloxamer and 45-55 parts of a 1wt% acetic acid aqueous solution. The preparation has excellent stability and probiotic compatibility, and the antibacterial spectrum is wider than that of existing essential oil. When the preparation is used as an animal feed additive, the daily gain of animals can be remarkably increased, and the diarrhea rate can be remarkably reduced, so that the preparation can be used as a substitute of antibiotics.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating infant intestinal angina pectoris, a massage medium and a preparation method of the massage medium. The traditional Chinese medicine composition is prepared from 4-8 parts of cortex cinnamomi, 8-12 parts of fructus evodiae, 8-12 parts of rhizoma zingiberis, 4-8 parts of flos carthami, 8-12 parts of rhizoma chuanxiong, 8-12 parts of flos caryophylli, 8-12 parts of cortex magnoliae officinalis and 10-20 parts of cortex eucommiae. The medicines are combined to warm the spleen and stomach to dispel cold and treat infant intestinal colic caused by spleen deficiency and middle cold. Oil, wax and the traditional Chinese medicine composition are combined to prepare the massage medium for treating the infantile intestinal colic, the massage medium can remarkably enhance the treatment effect of infantile massage, and clinical experiment data show that the total effective rate of the massage medium for treating the infantile intestinal colic is 93.3%.

This invention provides a traditional Chinese medicine composition and a hot compress for postoperative rehabilitation after gynecological laparoscopic surgery, belonging to the technical field of traditional Chinese medicine hot compresses. The traditional Chinese medicine composition of this invention comprises the following raw materials by weight: 4-6 parts of Artemisia argyi, 6-10 parts of vinegar-processed Corydalis yanhusuo, 12-18 parts of Clematis chinensis, 20-30 parts of processed Evodia rutaecarpa, and 6-10 parts of stir-fried Atractylodes macrocephala. The traditional Chinese medicine composition can be further mixed with 250-350 parts of coarse salt to prepare a hot compress. When applied to patients after gynecological laparoscopic surgery, the traditional Chinese medicine composition and hot compress of this invention can significantly shorten the time to the first bowel sound and first flatus, reduce the incidence of postoperative abdominal distension, especially reducing the risk of severe abdominal distension; at the same time, it effectively relieves shoulder and neck pain, improving postoperative comfort and patient satisfaction.

The present application belongs to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition and application thereof. The present application takes the core principle of 'nourishing blood and activating blood, inhibiting estrogen and removing spots' as the core principle, is based on traditional Chinese medicine internal regulation and treatment of the root, and inhibits the formation of chloasma from the root by regulating estrogen balance. The traditional Chinese medicine composition is composed of eight medicines including Evodia rutaecarpa, cornu cervi, Angelica sinensis, Ligusticum chuanxiong, Radix Rehmanniae Preparata, Radix Paeoniae Alba and honeycomb, can significantly fade the skin lesions and reduce the recurrence rate, is safe, non-toxic, has long-lasting efficacy, and has outstanding clinical advantages. The present application is superior to the commonly used western medicine when used alone, and can synergistically enhance the efficacy when combined with the western medicine, and provides a new Chinese medicine selection for the treatment of chloasma.

The invention relates to a traditional Chinese medicine composition for treating cold evil stomach invading type epigastric pain and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by weight: 4-8 parts of processed radix aconiti carmichaeli, 6-10 parts of rhizoma zingiberis, 6-10 parts of rhizoma galangae, 3-5 parts of cortex cinnamomi, 3-5 parts of fructus evodiae, 8-12 parts of rhizoma atractylodis, 6-10 parts of cortex magnoliae officinalis, 6-10 parts of pericarpium citri reticulatae, 8-12 parts of rhizoma corydalis, 10-15 parts of radix paeoniae alba, 4-8 parts of flos carthami and 4-8 parts of honey-fried licorice root. Compared with the prior art, the traditional Chinese medicine composition is definite in curative effect, high in safety and free of obvious toxic and side effects, can effectively relieve symptoms such as gastral cavity crymodynia, fullness and belching, sour regurgitation and the like and reduce relapse, and has good clinical application prospects and popularization value.

The present application belongs to the field of traditional Chinese medicine, and relates to medical uses of Sishen pills or extracts thereof. Specifically, any one selected from items (1)-(3) below in the preparation of a drug for sedative-hypnotic, treatment or prevention of insomnia, anti-anxiety, or sleep regulation: (1) a pharmaceutical composition comprising Myristicae Semen, Fructus Psoraleae, Schisandra chinensis, Evodia rutaecarpa, Fructus Jujubae, and Zingiber officinale; (2) an extract which is a water extract and / or an ethanol extract of the pharmaceutical composition in item (1); and (3) a pharmaceutical preparation comprising the extract in item (2) and one or more pharmaceutically acceptable excipients. The pharmaceutical composition, extract or pharmaceutical preparation described in the present application has good sedative-hypnotic, prophylactic or therapeutic effects on insomnia, or sleep regulation.

The invention discloses a traditional Chinese medicine composition for treating metabolic syndrome as well as a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following ten raw material medicines in specific parts by weight: poria cocos, roasted rhizoma atractylodis macrocephalae, raw radix astragali, roasted radix puerariae, white mulberry root-bark, folium mori, herba lycopi, ginger processed pinellia, fructus citri and fructus evodiae. The prescription is based on the treatment rule of invigorating spleen and replenishing qi, clearing damp and dissolving turbidity, and regulating qi and activating blood circulation in traditional Chinese medicine, and the compatibility of monarch, minister, assistant and guide is scientific. The composition can improve the metabolic syndrome in a multi-target manner, can effectively reduce the body weight of a patient, and can reduce blood sugar, blood pressure, blood fat and inflammatory factor levels. The invention also provides a preparation method of the composition and application of the composition in preparation of drugs for treating metabolic syndrome, reducing blood sugar, reducing blood fat, reducing blood pressure or losing weight.

The invention belongs to the technical field of extraction of active ingredients of traditional Chinese medicines and natural medicines, and particularly relates to a method for extracting alkaloid compounds in fructus evodiae. The extraction method comprises the following steps: mixing evodia rutaecarpa powder and a deep-eutectic solvent, and carrying out ultrasonic extraction to obtain the alkaloid compound, the eutectic solvent comprises a hydrogen bond acceptor and a hydrogen bond donor; the hydrogen bond receptor is menthol; the hydrogen bond donor is formic acid. According to the method disclosed by the invention, the eutecticevaporate solvent is used for extracting the fructus evodiae powder under the assistance of ultrasonic waves, the extraction rate of alkaloid compounds is high, and the evodiamine, the rutaecarpin, the 1-methyl-2-nonylquinoline-4 (1H)-ketone, the 1-methyl-2-undecyl-4 (1H)-quinolone, the evodiamine, the 1-methyl-2-[(6Z, 9Z)-6, 7, 8-tetramethyl-1, 3, 4, 5, 6-tetramethyl-1, 3, 5-tetramethyl-1, 3, 5-tetramethyl-1, 3, 5-tetramethyl-1, 3, 5-tetramethyl-1, 3 The compound is composed of seven target compounds, i.e., 2, 3, 4, 6, 7, 9-pentadecadiene]-4 (1H)-quinolone and dihydroevodia rutaecarpin.

This invention provides a traditional Chinese medicine composition for hiccups, acid reflux, and / or bloating, its application, and a drug with the traditional Chinese medicine composition as an active ingredient and its preparation method. The traditional Chinese medicine composition of this invention comprises the following medicinal materials in parts by weight: 3-9 parts agarwood, 3-10 parts processed Evodia rutaecarpa, 10-20 parts cuttlebone, 6-12 parts patchouli, 3-10 parts perilla leaf, 6-12 parts Elsholtzia ciliata, 6-12 parts tangerine peel, 6-10 parts Magnolia officinalis, 6-12 parts Amomum villosum, 6-12 parts stir-fried white hyacinth bean, 6-20 parts stir-fried hawthorn, 3-6 parts Coptis chinensis, 6-12 parts stir-fried malt, 6-15 parts Poria cocos, 3-6 parts licorice root, 6-12 parts talc, 6-15 parts green plum blossom, 3-6 parts cinnamon, and 3-9 parts stir-fried fennel. The traditional Chinese medicine composition of the present invention, when used together, has the combined effects of regulating qi and stomach, relieving nausea and hiccups, neutralizing acid and relieving bloating, strengthening spleen and promoting digestion, and warming the middle and removing dampness. It treats both the symptoms and the root cause, and has a definite and lasting curative effect.

The invention relates to a traditional Chinese medicine composition for treating allergic rhinitis as well as a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition for treating allergic rhinitis comprises the following raw materials in parts by weight: 25-35 parts of astragalus membranaceus, 25-35 parts of hairyvein agrimony, 25-35 parts of clinacanthus nutans, 25-35 parts of penthorum chinense pursh, 8-13 parts of codonopsis pilosula slices, 8-13 parts of bran-fried atractylodes macrocephala koidz and the like. Compared with the prior art, the traditional Chinese medicine composition has the advantages that the astragalus membranaceus, the hairyvein agrimony, the clinacanthus nutans and the penthorum chinense pursh are used as main functional raw materials, and an ultrasonic-microwave synergistic extraction technology and a gradient elution technology are combined, so that the treatment effect of the obtained traditional Chinese medicine composition on the allergic rhinitis is remarkably improved, and a new treatment means is provided for allergic rhinitis patients; the application prospect is wide.

The invention provides a stem cell secretion combined preparation for improving skin elasticity, and belongs to the technical field of biology. The preparation uniquely combines the umbilical cord mesenchymal stem cell exosome and the piper longum fruit exosome which is specially optimized and extracted. Wherein advanced processes such as liquid nitrogen quick freezing, low-temperature homogenization, multi-stage centrifugation, ultrafiltration concentration and the like are adopted for preparing the piper longum fruit exosome, so that the high activity and the purity of the piper longum fruit exosome are ensured. Experimental results show that the composition shows a remarkable synergistic effect and can effectively promote proliferation of human skin fibroblasts and expression of elastin. More importantly, in an ultraviolet injury mouse model, the combined preparation can remarkably improve the skin elasticity and promote collagen synthesis, so that photoaging is effectively resisted, and the skin elasticity is comprehensively improved. The invention provides an efficient and innovative biological solution for anti-aging and repair of skin, and has a wide application prospect.

The invention relates to the technical field of traditional Chinese medicine preparations, and particularly discloses a traditional Chinese medicine foot bath composition for treating insomnia and a preparation method thereof.The traditional Chinese medicine foot bath composition is prepared from, by weight, 5-15 parts of folium artemisiae argyi, 5-15 parts of flos carthami, 3-9 parts of fructus evodiae, 5-15 parts of baked ginger, 20-40 parts of poria with hostwood, 3-9 parts of pepper, 3-9 parts of herba ephedrae, 5-15 parts of caulis spatholobi and 10-30 parts of caulis polygoni multiflori. Water extracts of all the raw materials and a pharmaceutically acceptable carrier are prepared into the foot bath preparation, the foot bath preparation specifically comprises a foot bath medicine bag, concentrated foot bath liquid and instant foot bath particles, the foot bath preparation is used for foot soaking and cannot be orally taken, and the preparation method comprises the following steps that S1, all the raw materials are weighed; and S2, removing mildew and impurities, and uniformly mixing the medicinal materials in the step S1. According to the traditional Chinese medicine foot bath composition for treating insomnia and the preparation method thereof, the formula is simple, scientific and reasonable, and the traditional Chinese medicine foot bath composition has the effects of warming and dredging, activating blood and soothing the nerves and has an exact curative effect on treating insomnia.

The present application relates to the technical field of traditional Chinese medicine. The purpose is to provide a traditional Chinese medicine hot compress for treating children's rhinitis, which comprises the following weight parts of traditional Chinese medicine raw materials: perilla seed 4-6 parts, radish seed 4-6 parts, white mustard seed 2-4 parts, xanthium 2-4 parts, cyperus 2-4 parts, asarum 1-2 parts, evodia 1-2 parts. The present application uses external application of medicine, the use mode is simple, and the patient compliance is high. Through precise proportioning of the prescription, the special prescription is suitable for special diseases, the force is special and one, and the chronic rhinitis patients can take the medicine for a long time, which is convenient, safe and reliable in curative effect. As a pure traditional Chinese medicine formula, its preparation and use are safer and more reliable than furazolidone and other hormone nasal drops in the treatment of rhinitis, and are green and safe.

The application discloses an alkaloid compound and an extraction method and application thereof, and belongs to the technical field of alkaloid compounds. After crushing, the Evodia fruit is subjected to acid extraction and alkali precipitation treatment, ethyl acetate extraction, water washing and drying in sequence to obtain Evodia total alkaloids; the Evodia total alkaloids are subjected to ODS medium-pressure column chromatography, reverse-phase semi-preparative HPLC separation, cyanogen column HPLC primary purification and cyanogen column HPLC secondary purification in sequence to obtain the alkaloid compound. The alkaloid compound provided by the application is prepared from traditional Chinese medicine Evodia, has an inhibiting effect on the proliferation of a colorectal cancer cell line (HCT-116), and can be applied to the preparation of an anti-colorectal cancer tumor drug.

The utility model relates to agricultural machinery and equipment technical field discloses a kind of evodia rutaecarpa harvesting machines, including mobile car body, two storage boxes, two lifting plates, lifting adjustment assembly, two multi-degree-of-freedom mechanical arms, two mounting seats, two shearing parts, two adaptive adjustment components one, two adaptive adjustment components two, two identification cameras, two hanging baskets, control panel and auxiliary turnover component;The storage box is fixedly installed at the both sides of mobile car body, the both sides of mobile car body are all provided with sliding slot, two lifting plates are slidably installed in corresponding sliding slot respectively, the lifting adjustment assembly is arranged in two sliding slots and is connected with two lifting plates, and two multi-degree-of-freedom mechanical arms are respectively arranged on corresponding lifting plate.The utility model has the following advantages and effects: it can effectively improve the evodia rutaecarpa harvesting efficiency, while greatly reducing the labor intensity of manual operation.

This invention provides a topical herbal patch for postpartum acute mastitis and its preparation method, belonging to the field of traditional Chinese medicine pharmaceutical technology. The patch is composed of *Paris polyphylla*, *Vaccaria segetalis*, *Uncaria rhynchophylla*, *Bombyx mori*, *Mild Glauber's salt*, processed *Evodia rutaecarpa*, *Citrus aurantium*, *Cirsium japonicum*, *Smilax china*, *Siegesbeckia orientalis*, stir-fried *Melia azedarach*, and licorice. Based on a rigorous formula of principal, assistant, and adjuvant herbs, this patch significantly reduces serum TNF-α, IL-1β, and IL-6 levels in mice with postpartum mastitis, and significantly improves the overall clinical efficacy. It rapidly relieves core symptoms such as breast redness, swelling, pain, and induration, clears milk stasis, and possesses multiple effects including anti-inflammatory, anti-swelling, lactation-promoting, and analgesic properties. This herbal patch is a topical care preparation that acts directly on the affected area of ​​the breast. The drug is absorbed transdermally without gastrointestinal metabolism, and its components do not affect the infant through breast milk. This provides a safe, efficient, and convenient new topical care solution for postpartum acute mastitis.