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44 results about "Cornus officinalis" patented technology

Cornus officinalis is a species of dogwood known also as Japanese cornel or Japanese cornelian cherry or Cornelian cherries, not to be confused with C. mas, which is also known as the "Cornelian cherry." The correct term would be Korean cornel dogwood or Chinese cornel dogwood since the flower originated from Korea and China.

A traditional Chinese medicine composition for treating male infertility of liver stagnation and kidney deficiency type, a preparation method and application thereof

PendingCN122398881ASerum pharmacochemistryKidney
This invention discloses a traditional Chinese medicine composition for treating male infertility due to liver stagnation and kidney deficiency, its preparation method, and its application, belonging to the fields of traditional Chinese medicine pharmaceutical technology and andrological reproductive health technology. The composition is formulated with Bupleurum chinense, Tribulus terrestris, Cynomorium songaricum, Cuscuta chinensis, Cornus officinalis, and Epimedium brevicornu in specific weight proportions, following the principles of soothing the liver and relieving stagnation, tonifying the kidney and replenishing essence, and unblocking the meridians to treat impotence. This invention employs an alcohol-water dual-phase fractional extraction process, and can be prepared into various dosage forms such as granules, capsules, and tablets. Pharmacological experiments have confirmed that the composition of this invention can increase sperm density and progressively motile sperm rate, improve penile tissue nitric oxide synthase (NOS) activity, regulate reproductive hormones, and reduce testicular oxidative damage; serum pharmacochemistry and metabolomics have clarified the active components entering the bloodstream and their pathways of action. This invention features a refined formulation, abundant medicinal resources, and simple preparation, making it suitable for large-scale production and clinical application in treating male infertility due to liver stagnation and kidney deficiency.
Owner:GUIZHOU MEDICAL UNIV

Fermented soup for improving growth and immune function of broiler chickens and preparation method thereof

The present application belongs to the technical field of animal health care, and particularly relates to a fermented decoction for improving growth and immune function of broilers and a preparation method thereof. The fermented decoction for improving growth and immune function of broilers is prepared from the following raw materials by fermentation according to weight parts: radix codonopsis 8-12 parts, angelica sinensis 3-7 parts, cornus officinalis 8-12 parts, cinnamomum cassia 3-7 parts and portulaca oleracea 3-7 parts. The fermented decoction significantly increases the body weight of broilers, significantly improves the thymus index and spleen index, and increases the IgG and IgM contents in serum, thereby promoting the growth of broilers and improving the immune function of broilers. The preparation method of the fermented decoction is simple, and is suitable for industrialized production and market promotion and application.
Owner:SHANDONG VOCATIONAL ANIMAL SCI & VETERINARY COLLEGE +1

Use of a traditional Chinese medicine composition in preparation of a medicine for regulating three highs

The present application belongs to the technical field of medicinal and edible Chinese medicine composition, and particularly relates to a kind of regulating three high compositions and application thereof.The regulating three high composition, by mass parts, raw materials include: yam 2040 parts, female privet fruit 1535 parts, dogwood 1535 parts, medlar 1025 parts, licorice 1020 parts, eucommia 1020 parts, white atractylodes 816 parts, hawthorn 515 parts, tuckahoe 312 parts.The present application takes yam, female privet fruit and dogwood as monarch drug;takes licorice, eucommia and medlar as minister drug;takes white atractylodes and hawthorn as auxiliary drug, and takes tuckahoe as servant drug;the whole party is used together, and the effect of regulating three high is realized by combining the functions of invigorating spleen and stomach, tonifying qi and nourishing blood, regulating liver and kidney and supplementing and purging.
Owner:GUANGDONG ZHENGHUIYUAN IND CO LTD

A color selection device for cornus officinalis

ActiveCN224542390UGear driveGear wheel
The utility model discloses a color sorting equipment for dogwood relates to agricultural product processing technical field, and its technical key points include transportation frame, the transportation frame outside bottom fixed mounting has the support frame, the transportation frame inside rotation is installed with two transportation rollers, the transportation frame outer wall fixed mounting has the motor with one of the transportation roller rotation axis connection, two the transportation roller outer wall all fixed mounting has a plurality of antiskid bosses, the utility model discloses a set of components such as transportation belt, rotating disc and gear are set up, and the transportation groove on the transportation belt surface can accurately limit dogwood, solve its small body easy to accumulate, the problem of rolling, guarantee the stable passage of the fruit alone color selection area, create good conditions for color identification, improve color selection accuracy greatly, and the rotating disc rotates synchronously with the transportation roller under the gear transmission, and the adjacent blanking groove and the transportation groove spacing is consistent, makes dogwood even orderly fall into, avoids the uneven interference of feeding, and the color selection efficiency is improved significantly.
Owner:FOPING CORNUS TECH DEV CO LTD

A traditional Chinese medicine composition for treating diabetic nephropathy

PendingCN122075621Areduce leakageno obvious damageMetabolism disorderUrinary disorderSalvia miltiorrhizaLow density lipoprotein cholesterol
This invention relates to a traditional Chinese medicine composition, specifically a traditional Chinese medicine composition for treating diabetic nephropathy, belonging to the fields of medicine and health products. The traditional Chinese medicine composition of this invention is made from components comprising the following raw materials: yam, salvia miltiorrhiza, rosehip, turtle shell, cornus officinalis, dioscorea hypoglauca, cuscuta chinensis, oyster shell, and American ginseng. Through rational formulation, this traditional Chinese medicine composition utilizes the principle of clearing heat and removing dampness, with the synergistic effect of multiple drugs, to significantly reduce fasting blood glucose, improve glucose metabolism, lower low-density lipoprotein cholesterol and triglycerides, and raise high-density lipoprotein cholesterol to regulate lipid metabolism, reduce weight, and has no significant damage to liver and kidney function, with minimal side effects.
Owner:DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE

Use of a traditional Chinese medicine composition in the preparation of a medicament for treating intestinal injury

This invention relates to the application of a traditional Chinese medicine composition in the preparation of a drug for treating intestinal injury. The traditional Chinese medicine composition comprises: 50-150 parts of ginseng, 60-180 parts of polygonatum, 40-90 parts of atractylodes, 30-58 parts of sophora flavescens, 60-180 parts of ophiopogon japonicus, 60-110 parts of rehmannia glutinosa, 40-90 parts of polygonum multiflorum, 60-180 parts of cornus officinalis, 40-90 parts of poria cocos, 35-58 parts of eupatorium fortunei, 35-58 parts of coptis chinensis, 35-90 parts of anemarrhena asphodeloides, 35-58 parts of epimedium, 40-110 parts of salvia miltiorrhiza, 60-180 parts of kudzu root, 80-140 parts of litchi seed, and 40-90 parts of lycium chinense root bark. The above-mentioned traditional Chinese medicine composition can inhibit the expression of TNF, AGE-RAGE, TLR and IL-17 and the infiltration of macrophages. It also helps to regulate the proliferation and differentiation of intestinal cells, restore beneficial bacteria in the intestine, and significantly improve the barrier function of the intestine, thereby effectively improving the damaged intestinal function.
Owner:SHIJIAZHUANG YILING PHARMA CO LTD

A pharmaceutical composition for treating cervical spondylosis, preparation and application thereof

The application discloses a kind of drug composition for treating cervical spondylosis and its preparation and application, belong to traditional Chinese medicine composition technical field, the drug composition includes the following component by weight fraction: 6-28 parts of cornus officinalis, 6-28 parts of antler, 6-20 parts of cassia twig, 6-30 parts of kudzu root, 10-40 parts of astragalus, 6-16 parts of peach kernel, 6-16 parts of safflower, 6-20 parts of purple salvia miltiorrhiza, 6-20 parts of wine dengue, 6-20 parts of chuanxiong, 6-20 parts of red peony root, 6-20 parts of turmeric, 6-20 parts of frankincense, 6-20 parts of myrrh, 6-20 parts of notopterygium, 6-20 parts of rinkhals, 6-20 parts of sea wind, 6-20 parts of giant knotweed, 6-20 parts of corydalis, 6-15 parts of licorice.The drug composition can be added pharmaceutically acceptable adjuvant, and be made into preparation.The drug composition and preparation can be used for preparing the drug for treating cervical spondylosis mainly with wind, cold and damp.
Owner:HUALONG SHENGAI TRADITIONAL CHINESE MEDICINE GRP CO LTD

A traditional Chinese medicine composition for treating constipation, a preparation method thereof and application thereof

PendingCN122440735ASalvia miltiorrhizaCannabis
The application discloses a traditional Chinese medicine composition for treating constipation, which is prepared from the following traditional Chinese medicine extracts: 20-30 parts of radix rehmanniae preparata, 15-25 parts of fructus corni, 10-20 parts of radix scrophulariae, 10-20 parts of radix ophiopogonis, 10-20 parts of prunus domestica, 9-15 parts of semen platycladi, 10-20 parts of semen cannabis, 4-6 parts of semen abri, 10-20 parts of bombyx batryticatus, 8-12 parts of angelica sinensis, 8-12 parts of salvia miltiorrhiza, 3-8 parts of prunus armeniaca, 8-12 parts of platycodon grandiflorum, 8-12 parts of fructus aurantii, 9-12 parts of pericarpium citri reticulatae, 4-8 parts of glycyrrhiza uralensis, and a preparation method thereof is disclosed. The application is used for treating constipation of the type of dry intestine due to yin deficiency by the treatment principles of tonifying kidney yin, tonifying heart yin, moistening the intestines, moistening the intestines with pungent flavor, promoting lung and regulating qi, lifting the cover of the pot, regulating qi and invigorating the spleen, and regulating and protecting the spleen and stomach.
Owner:THE SECOND AFFILIATED HOSPITAL OF NANJING UNIV OF TRADITIONAL CHINESE MEDICINE (JIANGSU SECOND HOSPITAL OF TRADITIONAL CHINESE MEDICINE JIANGSU TRAINING CENT FOR TRADITIONAL CHINESE MEDICINE MANAGEMENT CADRES)

Application of a traditional Chinese medicine composition in the preparation of a drug for nervous headache

ActiveCN117530987BPaeonia suffruticosaSerotonin
This invention relates to the application of a traditional Chinese medicine composition in the preparation of a drug for neurogenic headache. The composition is characterized by being prepared from Rehmannia glutinosa (processed), Cornus officinalis, Dioscorea opposita, Alisma plantago-aquatica, Paeonia suffruticosa, and Poria cocos. The composition significantly reduces the number of head scratches in rats with nitroglycerin-induced neurogenic headache, decreases the levels of neurogenic headache-related factors (NO, CGRP) in plasma, improves reserpine-induced low serotonin (5-HT) symptoms in mice, and increases clotting time, suggesting that this traditional Chinese medicine composition has a good therapeutic effect on neurogenic headache.
Owner:JIANGSU KANION PHARMA CO LTD

Compound traditional chinese medicine composition for treating diabetic nephropathy and use thereof

PCT designated stageWO2026129500A1Metabolism disorderUrinary disorderDiabetic kidneyCornus officinalis
Disclosed are a compound traditional Chinese medicine composition for treating diabetic nephropathy, a method for preparing same, and use thereof. The compound traditional Chinese medicine composition is prepared from Astragali Radix, Atractylodis Macrocephalae Rhizoma, Corni Fructus, Cinnamomi Cortex, Psoraleae Fructus, Rehmanniae Radix, Eucommiae Cortex, Achyranthis Bidentatae Radix, and Schisandrae Chinensis Fructus. Marsdenia tenacissima Caulis may also be added to the substance of the compound traditional Chinese medicine composition.
Owner:TIANJIN TASLY DIGITAL INTELLIGENCE CHINESE MEDICINE TECHNOLOGY CO LTD

Compound traditional chinese medicine composition for treating diabetic nephropathy and application thereof

PendingCN122272695ADiabetic kidneyAchyranthes bidentata
This invention relates to a compound traditional Chinese medicine composition for treating diabetic nephropathy and its application. The invention provides a traditional Chinese medicine composition 1 for treating diabetic nephropathy, which is prepared from Astragalus membranaceus, Atractylodes macrocephala, Cornus officinalis, Cinnamomum cassia, Psoralea corylifolia, Rehmannia glutinosa, Eucommia ulmoides, Achyranthes bidentata, and Schisandra chinensis. The invention further provides a traditional Chinese medicine composition 2 for treating diabetic nephropathy, which is prepared from Astragalus membranaceus, Atractylodes macrocephala, Cornus officinalis, Cinnamomum cassia, Psoralea corylifolia, Rehmannia glutinosa, Eucommia ulmoides, Achyranthes bidentata, Schisandra chinensis, and Clematis chinensis.
Owner:TIANJIN TASLY DIGITAL INTELLIGENCE CHINESE MEDICINE TECHNOLOGY CO LTD

A blood-nourishing and kidney-tonifying pill for treating lower back pain due to kidney yin deficiency.

This invention discloses a blood-nourishing and kidney-tonifying pill for treating lower back pain due to kidney yin deficiency, prepared from the following Chinese medicinal herbs in parts by weight: 25-35 parts Rehmannia glutinosa, 20-30 parts Cornus officinalis, 18-22 parts Eucommia ulmoides, 15-25 parts Achyranthes bidentata, 20-30 parts Angelica sinensis, 22-30 parts Ligusticum chuanxiong, 20-28 parts Salvia miltiorrhiza, 15-25 parts Curcuma zedoaria, 20-30 parts Citrus reticulata peel, 10-20 parts Cyperus rotundus, 15-25 parts Bupleurum chinense, and 20-30 parts Atractylodes macrocephala. The formula contains 0 parts of Rehmannia glutinosa, 15-25 parts of Citrus aurantium, 18-22 parts of Amomum villosum, 20-30 parts of Scutellaria baicalensis, 15-25 parts of Morus alba root bark, 10-20 parts of bitter apricot kernel, and 15-25 parts of Eriobotrya japonica leaf. The whole formula contains Rehmannia glutinosa, Cornus officinalis, Eucommia ulmoides, Achyranthes bidentata, Angelica sinensis, Ligusticum chuanxiong, Salvia miltiorrhiza, Curcuma zedoaria, Citrus reticulata peel, Cyperus rotundus, Bupleurum chinense, Atractylodes macrocephala, Citrus aurantium, Amomum villosum, Scutellaria baicalensis, Morus alba root bark, bitter apricot kernel, and Eriobotrya japonica leaf. It nourishes blood and tonifies the kidneys to treat kidney yin deficiency and lower back pain, and its preparation method is disclosed.
Owner:NANJING TONGRENTANG PHARM CO LTD

Traditional Chinese medicine composition for treating dry mouth of Sjogren's syndrome and preparation method thereof

This invention belongs to the field of traditional Chinese medicine preparation technology, specifically relating to a traditional Chinese medicine composition for treating dry mouth in Sjögren's syndrome and its preparation method. The traditional Chinese medicine composition includes the following raw materials in parts by weight: 10g Rehmannia glutinosa, 9g Scrophularia ningpoensis, 10g Ophiopogon japonicus, 10g Fagopyrum dibotrys, 10g Phragmites communis, 6g Amomum villosum, and 3g Bletilla striata. Depending on clinical diagnosis, other herbs such as Cornus officinalis, Trichosanthes kirilowii, Lophatherum gracile, Paeonia suffruticosa, and Poria cocos may be selectively added. The preparation method includes two decoctions, filtration, and combining the filtrates. It is derived from the Kidney-Nourishing, Heat-Clearing, and Yin-Nourishing Decoction, retaining the core of the Fluid-Increasing Decoction, and adding three lung / stomach meridian-invigorating herbs: Fagopyrum dibotrys, Phragmites communis, and Bletilla striata. The core treatment principle is to nourish yin and generate fluids, clear heat and remove blood stasis, promote tissue regeneration and wound healing, and harmonize the spleen and stomach. Clinical observation shows that it can significantly reduce the VAS score for dry mouth in patients with Sjögren's syndrome, increase static salivary flow rate, and promote the recovery of oral mucosal ulcers and angular cheilitis. It has good safety and can be taken orally for overall conditioning or used as a mouthwash to directly target the affected area.
Owner:航空总医院

Traditional Chinese medicine for treating diabetic neuropathy and preparation method thereof

This application relates to the field of traditional Chinese medicine pharmaceutical technology, and discloses a traditional Chinese medicine for treating diabetic neuropathy and its preparation method. The traditional Chinese medicine is prepared from Coptis chinensis, Corydalis yanhusuo, Schisandra chinensis, Cornus officinalis, Astragalus membranaceus, and Cinnamomum cassia. The preparation method includes: low-temperature differential pretreatment of the raw materials; gas-phase assisted mechanical activation of components A and C under pressurized carbon dioxide environment, utilizing in-situ generation of carbamate intermediates in the gas phase to reduce lattice energy; subsequently, component B is added and pulsed milling is performed, directionally assembling into a hydrophobic ion-pair complex through a thermodynamically driven ligand substitution reaction; finally, the pressure and temperature are increased in situ to convert the reaction medium into a supercritical fluid for integrated extraction. This invention achieves the transformation of the active ingredient from a hydrophilic to a lipophilic chemical form through a gas-phase activation and stepwise substitution strategy, enabling it to effectively penetrate the blood-nerve barrier. Simultaneously, the low-temperature, anaerobic environment throughout the process effectively avoids the degradation of heat-sensitive components.
Owner:NINGXIA HUI AUTONOMOUS REGION TRADITIONAL CHINESE MEDICINE HOSPITAL (NINGXIA HUI AUTONOMOUS REGION TRADITIONAL CHINESE MEDICINE RESEARCH INSTITUTE)

Use of a traditional Chinese medicine composition in the preparation of a cardiovascular protective drug for myocardial infarction after PCI

PendingCN122163746ACardiovascular disorderPlant ingredientsProtective drugsAconitum carmichaeli
This invention provides the application of a traditional Chinese medicine composition in the preparation of cardiovascular protective drugs after percutaneous coronary intervention (PCI) for myocardial infarction, specifically acute ST-segment elevation myocardial infarction (STEMI), with a TCM syndrome of "heart yang deficiency." The composition comprises raw Cornus officinalis, dried ginger, ginseng, Astragalus membranaceus, Atractylodes macrocephala, Alisma plantago-aquatica, Poria cocos, and Aconitum carmichaelii. The cardiovascular protective effects of this composition include improving cardiac function, inhibiting postoperative oxidative stress, reducing NT-proBNP, and decreasing the risk of cardiovascular events within one year post-surgery. It can be prepared as a decoction, oral liquid, or other dosage forms, and can be used in combination with conventional Western medicine treatments for synergistic effects. The composition of this invention is scientifically formulated, targets multiple points of action, and effectively addresses the problem of limited cardiovascular protection methods after PCI in STEMI patients, significantly improving patient prognosis and demonstrating good clinical application value.
Owner:GUANGDONG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE HAINAN HOSPITAL

A medicinal and edible food formula for improving yang deficiency constitution, preparation process and application

PendingCN122271518ABiotechnologyMedicinal herbs
This invention discloses a food-medicine homology formula, preparation process, and application for improving Yang deficiency constitution, relating to the field of food preparation technology. The food-medicine homology formula, preparation process, and application for improving Yang deficiency constitution includes Ganoderma lucidum, Codonopsis pilosula, Astragalus membranaceus (processed), Lentinus edodes, Poria cocos, Dolichos lablab, Tremella fuciformis, Dioscorea opposita, Rehmannia glutinosa (processed), Cornus officinalis, Eucommia ulmoides leaf, Lycium barbarum, Angelica sinensis, Prunus persica kernel, Jujube, Glycyrrhiza uralensis (processed), Cinnamomum cassia, Citrus medica, Citrus reticulata peel, and Amomum villosum. This food-medicine homology formula is simple to prepare, using only medicinal and edible herbs or ingredients. The excipients used also comply with national food safety standards for food additives, ensuring safety for consumption. Long-term consumption has a good effect on improving Yang deficiency constitution. The process is suitable for large-scale industrial production, simultaneously replenishing Qi and assisting Yang, strengthening the body's foundation, and having a significant warming and nourishing effect on Yang deficiency constitution.
Owner:路传涛

A traditional Chinese medicine composition for treating diabetic foot and a preparation method thereof

PendingCN122251497AMetabolism disorderMammal material medical ingredientsFoot ulcersCoptis
The present application relates to the field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating diabetic foot and a preparation method thereof.The traditional Chinese medicine composition is made of the following weight parts of traditional Chinese medicine raw materials: 180-220 parts of raw astragalus, 140-160 parts of angelica, 90-120 parts of dogwood, 180-220 parts of coptis, 180-220 parts of scrophulariaceae, 90-120 parts of atractylodes, 90-120 parts of cortex phellodendri, 40-60 parts of white yam, 40-60 parts of pearl powder, 40-60 parts of geum japonicum and 4-8 parts of artificial musk.The traditional Chinese medicine composition has the effects of benefiting qi and nourishing blood, nourishing yin and purging fire, clearing heat and drying dampness, promoting blood circulation and generating muscle, and has a good therapeutic effect on foot ulcer caused by diabetes.Moreover, the traditional Chinese medicine composition is safe and effective for long-term use, and the patient is not prone to recurrence.
Owner:HENAN KUNLIN MIAOJIAN PHARMACEUTICAL TECHNOLOGY CO LTD

A method for determining the content of wine cornus officinalis and ginkgo biloba in yinlingtongmai jian nao granules

ActiveCN117388392BComponent separationBiotechnologyRhamnetin
The present application provides a kind of determination wine Jumu and ginkgo leaf content in Yining Tongmai Jian Nao Granules, adopts liquid chromatography to determine the content of monorin, strychnos seed, kaempferol, isorhamnetin, including being analyzed by liquid chromatograph, with the mixed solution of monorin control product, strychnos seed control product being prepared as a mixed control product solution, with the mixed solution of kaempferol control product, isorhamnetin control product being prepared as another mixed control product solution, with the solution of Yining Tongmai Jian Nao Granules sample being prepared as test product solution, corresponding chromatographic conditions are set respectively, are precisely sucked respectively, then are injected into liquid chromatograph respectively, and content is determined.The quality of Yining Tongmai Jian Nao Granules is evaluated by the detection of the present application by liquid chromatography, which can better reflect the internal quality of the compound granules and better control the quality of Yining Tongmai Jian Nao Granules.
Owner:HUNAN BUTIAN PHARMA

Traditional Chinese medicine for diabetes osteoporosis and preparation method thereof

PendingCN122163711AMetabolism disorderSkeletal disorderMedicinal herbsPaeonia suffruticosa
This invention discloses a traditional Chinese medicine for diabetic osteoporosis and its preparation method. The medicine is composed of Rehmannia glutinosa (processed), Cornus officinalis, Dioscorea opposita, Alisma plantago-aquatica, Poria cocos, Paeonia suffruticosa, Epimedium brevicornu, Angelica sinensis, and Achyranthes bidentata. Achyranthes bidentata is extracted using a eutectic solvent with choline chloride and oxalic acid in a 1:1 weight ratio before being used in the medicine. The preparation method is as follows: Achyranthes bidentata is extracted using a eutectic solvent to obtain an extract; the remaining herbs are decocted in water, and the two extracts are combined. Pharmacological tests show that this invention can significantly improve loose stools caused by the cloying and greasy nature of Rehmannia glutinosa, and the effect is superior to that of traditional decoction. This invention effectively reduces gastrointestinal side effects and is suitable for long-term use by patients with diabetic osteoporosis.
Owner:LIANYUNGANG SECOND PEOPLES HOSPITAL (LIANYUNGANG CLINICAL TUMOR RES INST)

A traditional Chinese medicine composition for treating cerebellar ataxia syndrome, a preparation method, a pharmaceutical preparation and applications

ActiveCN119236022BCerebellar ataxiaWolfiporia extensa
This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a traditional Chinese medicine composition, preparation method, pharmaceutical formulation, and application for treating cerebellar ataxia syndrome. The composition comprises the following components: Rehmannia glutinosa (raw and processed), Cistanche deserticola, Morinda officinalis, Cornus officinalis, Dendrobium nobile, Curculigo orchioides, Panax ginseng, Ophiopogon japonicus, Polygala tenuifolia, Acorus tatarinowii, Angelica dahurica, Poria cocos, Schisandra chinensis, Citrus reticulata peel, and Amomum villosum. The preparation method involves first soaking Rehmannia glutinosa (raw and processed) to obtain mixture A; then mixing the remaining ingredients and soaking them in water to obtain mixture B; finally, combining mixture A and mixture B, and decocting to obtain the final product. This traditional Chinese medicine formula can treat cerebellar ataxia syndrome, improving the main symptoms of ataxia such as gait instability, balance disorders, and dysarthria; it also helps to resolve turbidity and improve secondary symptoms such as bowel and bladder dysfunction, sleep disorders, and mental disorders, promoting patient compliance, slowing and stabilizing disease progression, and improving patients' quality of life.
Owner:WENZHOU TRADITIONAL CHINESE AND WESTERN MEDICINE HOSPITAL

A traditional Chinese medicine composition for treating diabetic nephropathy, its pharmaceutical preparation and application.

ActiveCN119925516BDiabetic kidneyJianpi yishen
This invention relates to the field of traditional Chinese medicine, specifically to a traditional Chinese medicine composition for treating diabetic nephropathy, its preparation method, and its application. The traditional Chinese medicine composition of this invention consists of the following raw materials in parts by weight: 10-60 parts of raw Astragalus membranaceus, 5-30 parts of Polygonatum sibiricum, 5-30 parts of Dioscorea opposita, 5-30 parts of Cornus officinalis, 3-15 parts of Coptis chinensis, 5-30 parts of Euonymus alatus, 5-30 parts of Arctium lappa, and 3-15 parts of Hirudo medicinalis. This invention optimizes the selection of raw materials and their compatibility, focusing on strengthening the spleen and replenishing the middle jiao, invigorating the spleen and benefiting the kidneys, strengthening the spleen and consolidating the kidneys, clearing heat and detoxifying, fully utilizing the synergistic therapeutic characteristics of traditional Chinese medicine with multiple components, pathways, and targets, and can significantly improve the clinical healing of patients with diabetic nephropathy. Preliminary small-scale clinical observations have found that the spleen-strengthening, kidney-benefiting, and heat-clearing formula can effectively improve the clinical symptoms and TCM syndromes of patients with diabetic nephropathy, reduce UACR values, and has good potential for widespread application.
Owner:SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M

A fast-dissolving compound microcapsule powder of traditional Chinese medicine and its preparation method

PendingCN122297424ABiotechnologyCyclodextrin
This invention provides a fast-dissolving compound microcapsule powder of traditional Chinese medicine and its preparation method, belonging to the field of health food technology. The microcapsule powder preparation method includes: sequentially extracting a mixture of Epimedium powder, Hovenia dulcis powder, Cornus officinalis powder, Pueraria lobata root, Morus alba fruit, and Citrus reticulata peel with 55-60% ethanol for a first extraction, followed by a second extraction with water to adjust the ethanol concentration to 45-50%, obtaining a mixed extract; concentrating and drying to obtain a powder of the traditional Chinese medicine extract; mixing this powder with maltodextrin, citric acid, and stevia to prepare a core material powder; preparing a capsule material solution with gum arabic, β-cyclodextrin, and konjac gum; and coating the core material surface with the capsule material using a fluidized bed, followed by solidification to obtain the final product. This invention achieves efficient extraction of components with different polarities through a combination of gradient alcohol extraction and fluidized bed microencapsulation technology, significantly improving product stability, hygroscopic resistance, and solubility, effectively masking unpleasant odors. The resulting microcapsule powder has synergistic effects of anti-fatigue and kidney tonification, is convenient to take, and is suitable for the health product field.
Owner:XICHANG COLLEGE +1

A traditional Chinese medicine composition for treating vascular cognitive impairment, a preparation method and application thereof

This invention discloses a traditional Chinese medicine composition for treating vascular cognitive impairment, its preparation method, and its application, belonging to the field of traditional Chinese medicine technology. It includes the following raw materials: stir-fried Atractylodes macrocephala, Fritillaria thunbergii, Ligusticum chuanxiong, Salvia miltiorrhiza, Curcuma longa, Acorus tatarinowii, Polygala tenuifolia, Cornus officinalis, Cistanche deserticola, Rehmannia glutinosa, Scrophularia ningpoensis, and borneol. Preparation method: First, the volatile oil is extracted by steam distillation and encapsulated with β-cyclodextrin; then, the lipid-soluble components in Salvia miltiorrhiza and Fritillaria thunbergii are extracted with ethanol; finally, the residue is combined with the remaining medicinal materials and decocted in water for extraction. Through the combination of Fritillaria thunbergii and borneol, the dual functions of "clearing inflammation + opening the blood-brain barrier" are achieved, increasing the brain concentration of lipid-soluble components such as tanshinone IIA. It significantly improves the learning and memory abilities of rats with vascular cognitive impairment, with efficacy superior to the Western medicine donepezil, and exhibits synergistic effects on multiple targets such as inhibiting NLRP3 inflammasomes and upregulating BDNF. This invention has a simple process, is suitable for industrial production, and has significant clinical application value.
Owner:NINGBO HOSPITAL OF TRADITIONAL CHINESE MEDICINE

A traditional Chinese medicine composition for treating liver disease, a preparation method and application thereof

PendingCN122351368ALycopus lucidusSalvia miltiorrhiza
This invention relates to the field of traditional Chinese medicine (TCM) technology and discloses a TCM composition for treating liver diseases. The composition, by weight, comprises at least the following ingredients: 10-14g of Salvia miltiorrhiza, 10-12g of Prunus persica, 10-12g of Rubia cordifolia, 13-17g of Lycopus lucidus, 13-17g of Polygonum cuspidatum, 10-12g of Cornus officinalis, 5-7g of Schisandra chinensis, 27-33g of Sedum sarmentosum, 27-33g of Atractylodes macrocephala, and 10-14g of Alisma plantago-aquatica. The preparation method of this TCM composition for treating liver diseases involves mixing the above ingredients, adding 400ml of water, bringing to a boil over high heat, and continuing to decoct for 30 minutes. The decoction is then filtered and extracted. Another method involves adding 400ml of water to the dregs, bringing to a boil over high heat, and continuing to decoct for 30 minutes. The decoction is then filtered and extracted. The two extractions are then combined. This traditional Chinese medicine composition for treating liver diseases is used to treat fatty liver hepatitis caused by blood stasis, toxin accumulation, dampness, spleen dysfunction, and liver yin deficiency. It has the effects of promoting blood circulation and detoxification, strengthening the spleen and promoting diuresis, and nourishing yin and softening the liver.
Owner:ZHEJIANG ZANGQIGE PHARMACEUTICAL CO LTD

A paste for improving cognitive function and a preparation method thereof

PendingCN122272747APinelliaCyclodextrin
This invention discloses a herbal paste for improving cognitive function and its preparation method, prepared from the following raw materials in parts by weight: Kidney-tonifying and marrow-nourishing components: 10-50 parts Rehmannia glutinosa, 10-50 parts Dioscorea opposita, 10-30 parts Cornus officinalis, 20-50 parts Tortoise shell glue, 20-50 parts Deer antler glue, 20-50 parts Dendrobium nobile; Spleen-tonifying and qi-boosting components: 10-15 parts Poria cocos, 5-50 parts Panax ginseng, 10-20 parts Atractylodes lancea, 10-30 parts Atractylodes macrocephala, 3-10 parts Amomum villosum; Phlegm-resolving and orifice-opening components: 10 parts Pinellia ternata. -15 parts, Citrus aurantium 6-9 parts, Bambusa textilis 6-12 parts, Citrus reticulata 6-9 parts, Acorus tatarinowii 5-15 parts, Polygala tenuifolia 10-20 parts, Alpinia oxyphylla 10-20 parts; Through the TCM theory of multi-dimensional synergistic regulation of "tonifying the kidney and replenishing essence, strengthening the spleen and replenishing qi, resolving phlegm and opening the orifices, clearing heat and promoting blood circulation, and warming yang and promoting qi circulation", combined with the systematic optimization of preparation processes such as water extraction-alcohol extraction synergistic extraction, β-cyclodextrin inclusion and vacuum concentration, a paste formula is provided to improve cognitive function and related psychosomatic symptoms, and improve the compliance and bioavailability of the medicine.
Owner:CHANGSHU MEIRENYU BIOTECHNOLOGY CO LTD