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336 results about "Cornus officinalis" patented technology

Cornus officinalis is a species of dogwood known also as Japanese cornel or Japanese cornelian cherry or Cornelian cherries, not to be confused with C. mas, which is also known as the "Cornelian cherry." The correct term would be Korean cornel dogwood or Chinese cornel dogwood since the flower originated from Korea and China.

Traditional Chinese medicine preparation fermentation liquor, preparation method thereof and application of traditional Chinese medicine preparation fermentation liquor in aspects of losing weight, lowering lipid and / or relieving liver injury

The invention discloses fermentation liquor of a traditional Chinese medicine preparation, a preparation method of the fermentation liquor and application of the fermentation liquor in the aspects of losing weight, lowering lipid and / or relieving liver injury. The traditional Chinese medicine preparation is prepared from the following components in parts by weight: 3 to 6 parts of mulberries, 3 to 6 parts of raspberries, 3 to 6 parts of fructus corni, 12 to 20 parts of fructus lycii, 15 to 25 parts of rhizoma polygonati, 15 to 25 parts of fructus crataegi and 2 to 5 parts of semen cassiae. The traditional Chinese medicine preparation is prepared by extracting, sterilizing, cooling, inoculating a leavening agent and fermenting. The mulberry, the raspberry and the dogwood which are medicinal and edible materials are used for replacing fleece-flower root, the original formula of the lipid-lowering drug is combined, the fermentation liquor prepared after fermentation can effectively retain the obesity adjusting effect of the classic formula of the lipid-lowering drug, meanwhile, the biological activity of the lipid-lowering drug is remarkably improved through the optimized compatibility and the probiotic fermentation technology, and the lipid-lowering drug has a good application prospect. A safe and efficient innovative scheme is provided for functional food to intervene in obesity / overweight.
Owner:YANGZHOU UNIV

Application of dendrobium extract in preparation of medicine for treating type 2 diabetes mellitus

ActiveCN120960338AMetabolism disorderOrganic non-active ingredientsSalvia miltiorrhizaCornus officinalis fruit extract
The invention discloses an application of a dendrobium extract in preparation of a medicine for treating type 2 diabetes, and mainly relates to the technical field of dendrobium. Particularly, the invention provides the dendrobium extract-containing medicine for treating the type 2 diabetes, so that the stability of components applied to the medicine for treating the type 2 diabetes in acidic, neutral and alkaline environments is improved, and the blood sugar rising amplitude is slowed down. Compared with the prior art, the medicine for treating type 2 diabetes mellitus prepared by the invention takes the dendrobium extract as a core and is matched with the synergistic emulsion, the rhizoma polygonati extract, the dogwood extract, the radix salviae miltiorrhizae extract, the bitter gourd extract, the vitamin B and the trace element chromium element; the traditional Chinese medicine composition disclosed by the invention can be used for synergistically regulating blood sugar metabolism, enhancing insulin sensitivity, improving microcirculation, stabilizing blood sugar, improving insulin resistance and lipid metabolism and enhancing immunity and cardiovascular functions, and a safe and effective medicine is provided for preventing and treating type II diabetes.
Owner:PENGJUN (GUANGZHOU) BIOTECHNOLOGY CO LTD

Composition for dispelling effects of alcohol and protecting liver and preparation method thereof

InactiveCN120550074AOrganic active ingredientsPeptide/protein ingredientsBiotechnologyCornus officinalis fruit extract
The invention discloses a hangover alleviating and liver protecting composition, which is prepared from the following components in parts by mass: 5 to 20 parts of radix puerariae extract, 5 to 20 parts of semen hoveniae extract, 5 to 20 parts of silybum marianum extract, 1 to 20 parts of rhizoma curcumae longae extract, 1 to 20 parts of rhizoma gastrodiae extract, 1 to 10 parts of lucid ganoderma extract, 1 to 20 parts of folium cortex eucommiae extract, 1 to 10 parts of fructus corni extract and 1 to 30 parts of corn oligopeptide powder. 1-50 parts of maltodextrin, 1-10 parts of microcrystalline cellulose, 1-2 parts of silicon dioxide and 1-2 parts of magnesium stearate. The total alcoholism-relieving and liver-protecting composition has the following beneficial effects: for acute drunkenness, the discomfort of drunkenness is obviously reduced, the chronic injury of alcohol to the liver is reduced, the systematic effect from alcohol metabolism to organ protection is realized through multi-target regulation and control, and the three-in-one effect of relieving alcoholism, protecting cells and regulating metabolism is achieved. The invention also discloses a preparation method of the alcohol effect dispelling and liver protecting composition.
Owner:ZHEJIANG BAIKEJIAN IND CO LTD

Traditional Chinese medicine compound for reducing urine protein, traditional Chinese medicine preparation and preparation method thereof

The invention discloses a traditional Chinese medicine compound for reducing urine protein, a traditional Chinese medicine preparation and a preparation method thereof, belongs to the technical field of traditional Chinese medicine compounds, and solves the problems that although the existing western medicine can reduce the urine protein level of a patient to a certain extent, the adverse reaction risk is high; the traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-30 parts of prepared rehmannia root, 10-30 parts of Chinese yam, 10-30 parts of dogwood, 10-20 parts of achyranthes root, 5-15 parts of schisandra chinensis, 5-15 parts of semen cuscutae, 10-30 parts of corn stigma, 10-30 parts of rhizoma alismatis, 10-30 parts of astragalus membranaceus, 10-30 parts of fried fructus rosae laevigatae, 10-30 parts of gordon euryale seed, 5-15 parts of flatstem milkvetch seed, 5-30 parts of salvia miltiorrhiza, 3-10 parts of wine-treated rhubarb and 3-5 parts of wine-treated coptis chinensis. According to the traditional Chinese medicine composition, all the medicines are compatible, all the components complement each other, the effects of reducing urinary albumin and protecting the kidney are increased, all the components are reasonably compatible, and the effect of coordinating and synergism is achieved.
Owner:TEACHING HOSPITAL OF CHENGDU UNIV OF T C M

Method for synergistically extracting dogwood seed oil and antioxidant peptide by coupling supercritical CO2 extraction with deep-eutectic solvent DES

The invention belongs to the technical field of food processing, and particularly relates to a method for synergistically extracting dogwood seed oil and antioxidant peptide by coupling supercritical CO2 extraction with deep-eutectic solvent DES. The method comprises the following steps: S1, performing microwave treatment on dogwood seeds, crushing and sieving to obtain dogwood seed powder; s2, the dogwood seed powder is subjected to supercritical CO2 extraction, a eutectic solvent serves as an entrainer, and residues A and dogwood seed oil are obtained after extraction is completed; s3, mixing the residue A with a deep eutectic solvent, and carrying out secondary extraction to obtain a residue B and a filtrate; s4, adding water into the filtrate, uniformly mixing, centrifuging, respectively collecting a water phase and an oil phase, carrying out reduced pressure distillation on the oil phase, and combining with the dogwood seed oil obtained in the step S2; and S5, adding the residue B obtained in the step S3 into water, and adding mixed enzyme to carry out enzymolysis reaction, so as to obtain the dogwood seed antioxidant peptide. According to the method, the dogwood seed oil and the antioxidant peptide can be extracted at the same time, the oil extraction rate of the dogwood seed oil reaches 90% or above, the yield of the antioxidant peptide is 78.7%, and the resource utilization rate is increased.
Owner:HENAN BUSINESS SCI RES INST +1

Pharmaceutical composition for treating benign prostatic hyperplasia and preparation method thereof

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a pharmaceutical composition for treating benign prostatic hyperplasia and a preparation method thereof. The composition is prepared from the following medicinal materials in parts by weight: 6 to 8 parts of radix aconiti lateralis preparata, 3 to 5 parts of cortex cinnamomi, 10 to 15 parts of fructus alpiniae oxyphyllae, 10 to 15 parts of fructus psoraleae, 5 to 10 parts of semen myristicae, 5 to 10 parts of ground beeltle, 8 to 12 parts of spina gleditsiae, 10 to 15 parts of radix angelicae sinensis, 8 to 12 parts of radix linderae, 15 to 20 parts of radix rehmanniae praeparata, 10 to 15 parts of fructus corni, 8 to 12 parts of rhizoma anemarrhenae, 15 to 20 parts of radix scrophulariae, 8 to 12 parts of rhizoma alismatis, 5 to 10 parts of radix stephaniae tetrandrae and 10 to 15 parts of radix cyathulae. The invention provides the self-prepared medicine composition for treating the prostatic hyperplasia, the diseases of patients with the prostatic hyperplasia are remarkably improved through the synergistic effect of all the medicines in the composition, and a new traditional Chinese medicine treatment thought is provided for clinical treatment of the BPH disease. According to the traditional Chinese medicine composition, medicine pairs are increased or decreased on the basis of referring to a traditional Chinese medicine classic treatment compound, the unique traditional Chinese medicine composition is finally formed, and all the medicine pairs in the formula cooperate with one another and are indispensable.
Owner:GUANGDONG PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE HAINAN HOSPITAL

Traditional Chinese medicine composition for reducing blood pressure and preventing heart diseases

The invention discloses a traditional Chinese medicine composition for reducing blood pressure and preventing heart diseases, and belongs to the technical field of traditional Chinese medicine preparation, and the traditional Chinese medicine composition is prepared from the following raw materials: selfheal, radix puerariae, eucommia ulmoides, salvia miltiorrhiza, ligusticum wallichii, radix paeoniae rubra, fructus trichosanthis, coptis chinensis, semen cassiae, angelica sinensis, radix paeoniae alba, rhizoma polygonati, dogwood, rhizoma atractylodis macrocephalae, poria cocos, radix cyathulae, radix curcumae, hawthorn and rheum officinale. The traditional Chinese medicine composition is suitable for people suffering from hypertension in the early stage, the middle stage and the later stage, has a good multi-target-point, targeted and broad-spectrum blood pressure lowering effect and a defecation effect, and can also protect the heart function, so that the risk of cardiovascular and cerebrovascular disease complications caused by hypertension lesion is reduced.
Owner:李广东

Traditional Chinese medicine composition for treating acute altitude sickness and preparation method thereof

The invention provides a traditional Chinese medicine composition for treating acute altitude sickness. The traditional Chinese medicine composition is prepared from ginseng, astragalus membranaceus, acanthopanax, rhodiola rosea, turnip, salvia miltiorrhiza, dogwood, poria cocos, rhizoma cimicifugae, radix bupleuri, platycodon grandiflorum, aster, elecampane, rhizoma anemarrhenae and liquorice. The traditional Chinese medicine composition disclosed by the invention can be used for treating the acute altitude sickness, remarkably prolonging the load-bearing swimming time of rats, remarkably increasing the arterial oxygen partial pressure and the arterial oxygen saturation of acute altitude sickness model rats and relieving physical fatigue, has obvious effects of resisting anoxia, improving acid-base balance and resisting inflammation, and has obvious curative effects on myocardial injury, liver injury, liver injury and the like. And the kidney injury can be protected.
Owner:INSTITUTE OF CHINESE MATERIA MEDICA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES

Kidney-tonifying and liver-nourishing compound preparation and preparation method thereof

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a kidney-tonifying and liver-nourishing compound preparation and a preparation method thereof. The compound preparation comprises 5-15 parts of roasted herba epimedii, 5-15 parts of fructus cnidii, 50-70 parts of roasted radix astragali and 10-30 parts of pulp of dogwood fruit. The traditional Chinese medicine composition has remarkable curative effects on various diseases and chronic strain caused by deficiency of liver and kidney and deficiency of blood and essence, such as dizziness, blurred vision, fatigue, swelling and pain of waist, back and limbs, dry mouth and eyes, limb ache and weakness, irregular menstruation, incapability of holding weight or hemiplegia and the like, and has a very good application prospect.
Owner:THE FIRST AFFILIATED HOSPITAL OF TIANJIN UNIV OF TRADITIONAL CHINESE MEDICINE

Bacteriostatic and antipruritic plant composition as well as preparation method and application thereof

PendingCN121177173ACosmetic preparationsToilet preparationsBiotechnologySanguisorba officinalis Root
The invention relates to the technical field of skin care product raw materials, and particularly discloses an antibacterial and antipruritic plant composition as well as a preparation method and application thereof. The preparation method of the antibacterial and antipruritic plant composition comprises the following steps: step 1) putting sanguisorba officinalis roots, pericarpium zanthoxyli fruits, gentiana australis, dracocephalum dracocephalum, artemisia capillaris and dogwood into water, and putting zymophyte for fermentation to obtain a fermented compound; (2) adding an ethanol water solution into the fermentation compound, heating, extracting, filtering, and taking filtrate to obtain a compound extracting solution; 3, the composite extracting solution is concentrated and dried, and the bacteriostatic and antipruritic plant composition is obtained, zymophyte is a compound of Weissella herlentini and zymozygous yeast.The bacteriostatic and antipruritic plant composition has the advantage that the bacteriostatic and antipruritic effect is further improved on the premise that low irritation is kept.
Owner:GUANGZHOU ZHENYAN COSMETICS CO LTD

Traditional Chinese medicine composition for treating depression and insomnia and application thereof

The invention discloses a traditional Chinese medicine composition for treating depression and insomnia and application thereof, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following raw material components in parts by weight: 10-15 parts of fermented soybean, 10-30 parts of lily, 10-15 parts of red wolfberry, 10-15 parts of radix puerariae, 10-30 parts of cistanche, 10-15 parts of longan aril, 10-30 parts of jujube, 9-30 parts of oyster, 10-15 parts of pawpaw, 3-10 parts of fingered citron, 5-15 parts of dogwood, 6-10 parts of fried gardenia, 15-30 parts of light wheat and 3-10 parts of honey-fried licorice root. Animal experiments and clinical tests prove that the traditional Chinese medicine composition can improve insomnia and depression symptoms at the same time. The traditional Chinese medicine composition has the overall regulation advantage of traditional Chinese medicine and the controllability of a modern preparation, and a safe and efficient treatment scheme is provided for depression and insomnia.
Owner:NINGXIA MEDICAL UNIV +1

Traditional Chinese medicine composition for preventing and treating premature ovarian failure and application thereof

ActiveCN120437251APowder deliveryAntinoxious agentsMedicinal herbsEndocrine functions
The invention discloses a traditional Chinese medicine composition for preventing and treating premature ovarian failure and application thereof. Belongs to the technical field of traditional Chinese medicine. The traditional Chinese medicine composition comprises gordon euryale seed, agilawood, sandalwood, processed rhizoma pinelliae, rheum officinale, amomum cardamomum, alpinia katsumadai, processed rhizoma arisaematis, processed radix aconiti, asarum, fructus aurantii and fructus piperis longi. The composition follows the compatibility principle of monarch, minister, assistant and guide in traditional Chinese medicine, belongs to a composite traditional Chinese medicine preparation, and needs to regulate the reproductive endocrine function through the synergistic effect of multiple medicinal materials. The traditional Chinese medicine focuses on phlegm-dampness stasis and kidney-yang deficiency type infertility and premature ovarian failure. The prior art purely focuses on tonifying the kidney (such as prepared rehmannia root and dogwood) or activating blood (such as peach kernel and safflower), while the formula disclosed by the invention integrates multiple effects of resolving dampness, warming and dredging, removing stasis, promoting the circulation of qi and the like, and is stronger in pertinence.
Owner:HUNAN ACAD OF CHINESE MEDICINE

Tableted candy capable of dispelling effects of alcohol and protecting liver and preparation method thereof

The tablet candy is prepared from the following raw materials in parts by weight: 25 to 30 parts of radix puerariae, 13 to 15 parts of semen hoveniae, 13 to 15 parts of ampelopsis grossedentata leaves, 13 to 15 parts of herba dendrodii officinalis, 8 to 11 parts of American ginseng, 8 to 11 parts of hericium erinaceus, 7 to 10 parts of fructus corni, 7 to 10 parts of flos chrysanthemi, 11 to 14 parts of poria cocos, 12 to 15 parts of semen coicis, 9 to 11 parts of corn stigma, 9 to 12 parts of pericarpium citri reticulatae and 4 to 7 parts of liquorice root. According to the tablet candy, radix puerariae and hovenia dulcis thunb are used as main materials, alcohol is directly decomposed, and the concentration of alcohol is reduced; the ampelopsis grossedentata leaves and the dendrobium officinale are used for protecting the liver and gastric mucosa, and substantive injuries caused by alcohol are reduced; american ginseng, hericium erinaceus, dogwood, chrysanthemum and other medicinal materials are used as auxiliary materials, so that the body is conditioned from multiple aspects of tonifying qi, nourishing stomach, clearing heat, tonifying liver and kidney and the like, and various discomfort after drinking is relieved; and finally, discharging metabolic wastes out of the body by using corn stigma, pericarpium citri reticulatae, poria cocos and the like, and regulating the whole body by using liquorice, thereby achieving the purposes of dispelling the effects of alcohol and protecting liver.
Owner:ZHEJIANG CHINESE MEDICAL UNIV MEDICAL PIECES

Cornus plant named β€˜Elsie Red’

A new cultivar of Cornus florida plant named β€˜Elsie Red’ that is characterized by its flowers that are bright red-pink in color (bracts) with yellow centers, its rapid growth habit, its good resistance to powdery mildew, and its flowers that are sturdy and have a high tolerance to wind.
Owner:IBARRA ROMAN MARTINEZ

Yang-tonifying health-care wine and preparation method thereof

The invention belongs to the technical field of health-preserving medicinal liquor, and particularly discloses yang-tonifying health-care liquor. The traditional Chinese medicine is prepared from the following traditional Chinese medicines in parts by weight: 2 to 5 parts of American ginseng, 10 to 20 parts of raspberry, 6 to 12 parts of herba cistanche, 3 to 7 parts of fructus alpiniae oxyphyllae, 12 to 16 parts of lucid ganoderma, 8 to 12 parts of fructus corni, 17 to 22 parts of fructus lycii, 1 to 4 parts of cortex cinnamomi, 13 to 17 parts of fructus hippophae, 30 to 80 parts of red dates, 8 to 16 parts of fructus hippophae powder and 2000 to 4000 parts of base wine. Aiming at the problem of physiological hypofunction caused by factors such as fatigue and pressure of modern males, the health-care wine takes pure grain white spirit as a carrier, and medicinal and edible medicinal materials such as American ginseng, raspberry, cistanche, fructus alpiniae oxyphyllae, lucid ganoderma, dogwood, medlar, cinnamon, sea-buckthorn and red dates are scientifically combined, so that a synergistic interaction effect is generated; the alcohol metabolism burden is relieved while kidney tonifying and essence securing are achieved, and safe and mild conditioning of kidney tonifying, essence securing, qi and blood regulating and metabolic protection is achieved.
Owner:SHANXI XIAONIUWA FOOD CO LTD

A traditional Chinese medicine composition for treating male infertility of liver stagnation and kidney deficiency type, a preparation method and application thereof

PendingCN122398881ASerum pharmacochemistryKidney
This invention discloses a traditional Chinese medicine composition for treating male infertility due to liver stagnation and kidney deficiency, its preparation method, and its application, belonging to the fields of traditional Chinese medicine pharmaceutical technology and andrological reproductive health technology. The composition is formulated with Bupleurum chinense, Tribulus terrestris, Cynomorium songaricum, Cuscuta chinensis, Cornus officinalis, and Epimedium brevicornu in specific weight proportions, following the principles of soothing the liver and relieving stagnation, tonifying the kidney and replenishing essence, and unblocking the meridians to treat impotence. This invention employs an alcohol-water dual-phase fractional extraction process, and can be prepared into various dosage forms such as granules, capsules, and tablets. Pharmacological experiments have confirmed that the composition of this invention can increase sperm density and progressively motile sperm rate, improve penile tissue nitric oxide synthase (NOS) activity, regulate reproductive hormones, and reduce testicular oxidative damage; serum pharmacochemistry and metabolomics have clarified the active components entering the bloodstream and their pathways of action. This invention features a refined formulation, abundant medicinal resources, and simple preparation, making it suitable for large-scale production and clinical application in treating male infertility due to liver stagnation and kidney deficiency.
Owner:GUIZHOU MEDICAL UNIV

Health-care deer medicinal liquor and preparation method thereof

The invention discloses health-care deer medicinal liquor and a preparation method thereof. The health-care deer medicinal liquor is prepared from the following raw materials in parts by weight: 80 to 120 parts of Chinese chive seeds, 80 to 120 parts of fructus schisandrae chinensis, 80 to 120 parts of polygala tenuifolia, 80 to 120 parts of fructus alpiniae oxyphyllae, 80 to 120 parts of rhizoma anemones altaicae, 80 to 120 parts of radix cyathulae, 80 to 120 parts of fructus corni, 80 to 120 parts of semen cuscutae, 40 to 60 parts of radix morindae officinalis, 160 to 240 parts of radix ophiopogonis, 160 to 240 parts of radix polygonati officinalis, 480 to 720 parts of mulberries, 30 to 50 parts of lucid ganoderma and 20 to 40 parts of cornu cervi pantotrichum. The invention solves the problems that the existing medicinal liquor preparation process is relatively simple, normal-temperature soaking is generally adopted, deep effective components of medicinal materials are difficult to fully extract, the fusion degree of the effective components and liquor is relatively low, and the final curative effect of the medicinal liquor is reduced.
Owner:HUBEI TIANYI HEALTH RESEARCH INSTITUTE (LLP)

Fermented soup for improving growth and immune function of broiler chickens and preparation method thereof

The present application belongs to the technical field of animal health care, and particularly relates to a fermented decoction for improving growth and immune function of broilers and a preparation method thereof. The fermented decoction for improving growth and immune function of broilers is prepared from the following raw materials by fermentation according to weight parts: radix codonopsis 8-12 parts, angelica sinensis 3-7 parts, cornus officinalis 8-12 parts, cinnamomum cassia 3-7 parts and portulaca oleracea 3-7 parts. The fermented decoction significantly increases the body weight of broilers, significantly improves the thymus index and spleen index, and increases the IgG and IgM contents in serum, thereby promoting the growth of broilers and improving the immune function of broilers. The preparation method of the fermented decoction is simple, and is suitable for industrialized production and market promotion and application.
Owner:SHANDONG VOCATIONAL ANIMAL SCI & VETERINARY COLLEGE +1

Qi and blood nourishing and anti-aging fermented traditional Chinese medicine compound as well as preparation process and application thereof

The invention discloses a fermented traditional Chinese medicine compound capable of nourishing qi and blood and resisting aging, which is a composition of a fermented product and an edible carrier thereof, wherein the fermented product is obtained by carrying out composite enzymolysis treatment on traditional Chinese medicinal materials with the effects of tonifying qi, enriching blood and resisting aging and then carrying out composite strain fermentation on the treated traditional Chinese medicinal materials. Wherein the traditional Chinese medicinal materials at least comprise qi-tonifying traditional Chinese medicinal materials selected from ginseng, codonopsis pilosula, astragalus membranaceus, radix pseudostellariae, bighead atractylodes rhizome, poria cocos and liquorice; the blood-enriching traditional Chinese medicinal materials are selected from angelica sinensis, prepared rehmannia roots, radix paeoniae alba, donkey-hide gelatin, longan aril and mulberries; the anti-aging traditional Chinese medicinal materials are selected from fructus lycii, glossy privet fruit, dogwood, polygonum multiflorum, polygonatum kingianum, ginseng and acanthopanax senticosus.
Owner:CHENGDU JIYANG HEALTH MANAGEMENT CO LTD +1

Traditional Chinese medicine composition and application thereof in preparation of medicine for relieving renal fibrosis caused by ferroptosis

The invention relates to a traditional Chinese medicine composition and application of the traditional Chinese medicine composition in preparation of a medicine for relieving renal fibrosis caused by ferroptosis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15 to 30 parts of radix salviae miltiorrhizae, 9 to 12 parts of radix et rhizoma rhei preparata, 8 to 18 parts of peach kernel, 5 to 15 parts of radix angelicae sinensis, 9 to 15 parts of radix achyranthis bidentatae, 4 to 10 parts of radix paeoniae rubra, 9 to 20 parts of herba dendrodii officinalis, 6 to 15 parts of fructus ligustri lucidi, 5 to 10 parts of fructus corni, 9 to 15 parts of herba centellae, 3 to 6 parts of radix notoginseng powder and 10 to 30 parts of radix astragali seu hedysari. Compared with the prior art, the traditional Chinese medicine composition provided by the invention can relieve kidney fibrosis caused by ferroptosis and reduce the score of kidney injury, and compared with a model group, the expression of GSH, TFR-1, SLC7A11 and GPX4 in the traditional Chinese medicine composition group is remarkably up-regulated, and the content of 4-HNE and MDA is remarkably reduced, so that the kidney injury caused by ferroptosis is relieved, and the kidney protection effect on patients with chronic kidney diseases is achieved.
Owner:SHANGHAI HOSPITAL OF TRADITIONAL CHINESE MEDICINE +1

Traditional Chinese medicine composition for treating xerophthalmia and relieving asthenopia and preparation method thereof

The invention belongs to the field of biological medicine, and particularly relates to a traditional Chinese medicine composition for treating xerophthalmia and relieving asthenopia and a preparation method thereof, the traditional Chinese medicine composition comprises mulberry leaf, chrysanthemum, cassia seed, wolfberry, rehmannia, dogwood, moutan bark, Chinese yam, lily, poria cocos, rhizoma alismatis, dendrobe, Chinese angelica, marigold, blueberry, lycium ruthenicum, raspberry, lutein ester and bear gall gold powder. Through the scheme, the traditional Chinese medicine composition provided by the invention can effectively treat clinical symptoms of xerophthalmia, increase tear secretion, improve fundus microcirculation and increase ciliary muscle blood flow, thereby eliminating asthenopia symptoms and improving eyesight.
Owner:HANGZHOU HEYON PHARM TECH CO LTD

Preparation method of dogwood extract and application of dogwood extract in bone strengthening products

PendingCN122031546ASkeletal disorderPharmaceutical non-active ingredientsCornus officinalis fruit extractUltrafiltration
The invention provides a preparation method of a dogwood extract and application of the dogwood extract in bone strengthening products, and belongs to the technical field of medicine extraction. The method comprises the following steps: (1) crushing a dogwood raw material, and immediately spraying an acid solution; (2) sequentially extracting the pretreated material by adopting an ethanol water solution containing citric acid and L-ascorbic acid as a first-phase extraction solvent and a phosphate buffer solution containing a compound enzyme preparation as a second-phase extraction solvent; (3) combining the extracting solutions, sequentially separating through an ultrafiltration membrane and at least two stages of nanofiltration membranes to obtain active fractions with different molecular weight intervals, and recombining the active fractions according to a preset proportion to obtain a refined solution; and (4) drying the refined liquid to obtain the dogwood extract. The preparation method provided by the invention has the advantages of high extraction rate of target active ingredients (especially aglycone), synergistic retention of multiple active ingredients, strong process controllability, suitability for large-scale production and the like.
Owner:ACE BIOTECHNOLOGY CO LTD

Model prediction optimization-based dogwood health wine soaking process

The invention provides a dogwood health wine soaking process based on model prediction optimization, and relates to the technical field of dogwood health wine soaking processes, and the dogwood health wine soaking process comprises the following steps: calculating a comprehensive cell wall degradation index, grading raw materials, and coding the graded raw materials into raw material quality grade values; establishing a first-order dissolution kinetic model, and performing parameter optimization in combination with a golden section search algorithm to obtain an optimal infusion temperature and an optimal infusion time; weighing the medicinal materials according to a preset ratio, mixing the medicinal materials with the base liquor, and starting to soak; arranging a two-parameter collaborative monitoring system in the soaking container; constructing a random forest model, predicting the dissolution completion degree and the predicted residual equilibrium time, performing dynamic regulation and control, and ending the dynamic regulation and control process when the prediction result meets the requirement to obtain an immersion liquid; and taking out the soaking liquid from the soaking container, and separating and purifying by adopting a secondary filtering process to obtain the dogwood health wine product. The technical defects that a traditional process depends on experience, parameters are solidified, and the monitoring means is single can be overcome.
Owner:HUBEI SIAN PHARM LTD CO

Traditional Chinese medicine external application preparation for sciatica and femoral head injury and auxiliary treatment equipment

The invention discloses a traditional Chinese medicine external application preparation for sciatica and femoral head injury and auxiliary treatment equipment. Taking the following materials: tonics: 10g of red ginseng, 10g of codonopsis pilosula, 10g of rhizoma polygonati, 10g of liquorice, 10g of angelica sinensis, 10g of turtle glue, 10g of radix rehmanniae, 10g of dogwood, 10g of cornu cervi pantotrichum, 10g of cistanche, 10g of morinda officinalis, 10g of herba epimedii, 10g of fructus psoraleae, 10g of semen cuscutae, 10g of eucommia ulmoides, 10g of teasel root, 10g of rhizoma drynariae, 10g of fructus alpiniae oxyphyllae, 10g of radix rehmanniae, 10g of turtle glue, 10g of rhizoma anemarrhenae, 10g of dogwood, 10g of parasitic The invention relates to the technical field of traditional Chinese medicine preparations, and has the beneficial effects that through the synergistic effect of compound optimization and intelligent equipment, the comprehensive treatment effects of efficient transdermal absorption, precise targeted treatment, safety and no side effect are realized, and the core problems of poor permeability, single curative effect, insufficient adaptability and the like of a traditional external treatment method are solved; and a safe, efficient and convenient solution is provided for sciatica and femoral head injury.
Owner:ηŽ‹δΉ‰ε‹

Traditional Chinese medicine composition for treating middle-jiao type diabetes mellitus as well as preparation method and application of traditional Chinese medicine composition

The invention discloses a traditional Chinese medicine composition for treating middle-jiao type diabetes as well as a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 15-30 parts of herba eupatorii, 10-20 parts of radix astragali, 8-15 parts of radix codonopsis, 1-3 parts of gypsum, 6-12 parts of radix rehmanniae preparata, 6-12 parts of radix rehmanniae recen, 9-15 parts of Chinese yam, 18-30 parts of radix trichosanthis, 12-20 parts of rhizoma anemarrhenae, 12-20 parts of radix ophiopogonis, 9-15 parts of dendrobe, 9-15 parts of radix polygonati officinalis, 3-6 parts of safflower, 3-6 parts of coptis chinensis, 9-15 parts of radix scrophulariae, 9-15 parts of dogwood, 6-10 parts of liquorice and 9-15 parts of seville orange flower. , 9-15 parts of loquat flower, 6-12 parts of penthorum chinense pursh and 6-12 parts of angelica keiskei. The traditional Chinese medicine composition is suitable for nourishing yin, moistening the lung, clearing the stomach, clearing heat, moistening dryness and promoting the secretion of saliva or body fluid, has a positive regulation effect on blood sugar and blood fat of diabetes patients, and is used for middle-digestion diabetes.
Owner:ZHEJIANG BAOZI BENCAO MEDICAL TECH CO LTD

Composition for improving constipation and diarrhea as well as preparation method and application thereof

The invention belongs to the technical field of medicinal and edible products, and particularly relates to a composition for improving constipation and diarrhea as well as a preparation method and application thereof. The composition for improving constipation and diarrhea provided by the invention comprises the following raw materials in parts by weight: Chinese yam, resistant dextrin, ginseng, radix ophiopogonis, poria cocos, dogwood, semen coicis, aronia melanocarpa freeze-dried powder, mulberry, radix polygonati officinalis, lycium ruthenicum freeze-dried powder, fructo-oligosaccharide and crystalline fructose. Experiments prove that through synergistic cooperation of the raw materials, the composition can effectively improve the diarrhea index of diarrhea rats, improve the intestinal barrier function, increase the villus length of small intestine tissues, reduce the depth of crypts, increase the water content of excrement of constipation mice and promote intestinal peristalsis, and has the effect of bidirectionally regulating diarrhea and constipation; the intestinal barrier function can be favorably repaired.
Owner:HEBEI JIDONG BIOTECHNOLOGY CO LTD

Traditional Chinese medicine composition for reinforcing qi and nourishing blood as well as preparation method and detection method thereof

PendingCN120478519AComponent separationUnknown materialsLigustrum vulgareSallow complexion
The invention discloses a traditional Chinese medicine composition for reinforcing qi and nourishing blood and a detection method thereof. The traditional Chinese medicine composition is prepared from ginseng, astragalus membranaceus, Chinese yam, lily, colla corii asini, roasted rhizoma atractylodis macrocephalae, pulp of dogwood fruit, ligustrum lucidum, schisandra chinensis, pericarpium citri reticulatae, rhizoma anemarrhenae, cornu cervi pantotrichum and lycium barbarum. According to the theory of traditional Chinese medicine, the prescription is screened by adopting the theory of treatment based on syndrome differentiation, and the medicines are scientifically and reasonably matched, have the effects of reinforcing qi, nourishing blood, consolidating the body resistance and strengthening the body resistance, and are used for treating shortness of breath, palpitation, lusterless complexion, weakness and weakness caused by deficiency of qi and blood. In addition, the traditional Chinese medicine composition can improve the body immunity of patients with deficiency of qi and blood, and can also be used for reducing adverse reactions such as myelosuppression and thrombocytopenia caused by radiotherapy and chemotherapy. Content determination is carried out through TLC identification and HPLC, and a scientific basis is provided for guaranteeing the clinical quality and effectiveness of reinforcing qi, nourishing blood and strengthening body resistance.
Owner:CHANGSHU LEI YUN SHANG PHARM CO LTD

Traditional Chinese medicine composition for qi deficiency, blood stasis and phlegm stagnation type coronary heart disease as well as preparation method and application of traditional Chinese medicine composition

The invention belongs to the technical field of cardiovascular disease treatment medicines, and particularly relates to a traditional Chinese medicine composition for qi deficiency, blood stasis and phlegm stagnation type coronary heart disease as well as a preparation method and application thereof. The traditional Chinese medicine composition comprises codonopsis pilosula, astragalus membranaceus, dogwood, rhizoma anemarrhenae, platycodon grandiflorum, radix bupleuri, rhizoma cimicifugae, rhizoma sparganii, curcuma zedoary, cassia twig, trichosanthes kirilowii maxim, allium macrostemon, rhizoma pinelliae preparata, Chinese yam and honey-fried licorice root. The traditional Chinese medicine composition can tonify qi, activate blood, eliminate phlegm and resolve turbidity, can be used for treating qi deficiency, blood stasis and phlegm stagnation type coronary heart disease, and can treat both symptoms and root causes. Experiments prove that for a mouse with coronary heart disease, the traditional Chinese medicine composition can obviously improve the heart function of the mouse, and has the effects of inhibiting atherosclerosis and regulating lipid metabolism; for patients with qi deficiency, blood stasis and phlegm stagnation type coronary heart disease, the traditional Chinese medicine composition can improve the symptoms of chest pain and chest distress of the patients. Therefore, the traditional Chinese medicine composition can be used for preparing a medicine for treating qi deficiency, blood stasis and phlegm stagnation type coronary heart disease, and can also be used for preparing a medicine for regulating blood fat.
Owner:THE FIRST AFFILIATED HOSPITAL OF HENAN UNIV OF TCM

Traditional Chinese medicine composition and preparation for treating knee osteoarthritis as well as preparation method and application of traditional Chinese medicine composition

The invention relates to the technical field of pharmaceutical preparations, in particular to a traditional Chinese medicine composition for treating knee osteoarthritis, a preparation as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 10 to 15 parts of herba epimedii, 10 to 15 parts of fructus corni, 15 to 25 parts of rhizoma dioscoreae nipponicae, 15 to 30 parts of rhizoma smilacis glabrae, 10 to 15 parts of radix gentianae macrophyllae, 3 to 6 parts of ground beeltle, 10 to 15 parts of spina gleditsiae, 10 to 15 parts of radix achyranthis bidentatae, 10 to 15 parts of cortex eucommiae, 3 to 6 parts of radix notoginseng, 10 to 15 parts of rhizoma drynariae, 10 to 15 parts of radix paeoniae alba, 15 to 30 parts of semen coicis and 3 to 6 parts of liquorice root. The traditional Chinese medicine compound provided by the invention integrates tonifying, blood activating, dampness eliminating and collateral dredging medicines, and avoids the limitation of pure tonifying or evil eliminating, so that the traditional Chinese medicine compound is more in line with the characteristics of KOA deficiency in root and excess in superficies. The traditional Chinese medicine composition is especially suitable for patients with complex knee osteoarthritis with symptoms such as deficiency of liver and kidney, rheumatic arthralgia and stagnation of blood stasis. In addition, through multi-target treatment, the formula gives consideration to both symptoms and root causes, not only aims at local symptoms of KOA, but also adjusts the overall function.
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE