The invention provides a
traditional Chinese medicine compound which is prepared from the following
raw material medicines: rhizoma smilacis glabrae, rhizoma dioscoreae septemlobae,
semen coicis, rhizoma curcumae longae, herba taxilli, radix salviae miltiorrhizae, cortex phellodendri, rhizoma acori graminei, plantain
herb, rhizoma atractylodis macrocephalae,
wine-treated rhubarb, radix angelicae pubescentis,
bran-fried rhizoma atractylodis and vinegar-treated rhizoma
corydalis, and also provides application of the
traditional Chinese medicine compound composition in medicines for treating
gout and gouty
nephropathy. In addition, the invention also provides a preparation method of the sustained-release granule of the compound composition, which comprises the following steps: firstly, preparing the raw medicinal materials into a
traditional Chinese medicine fluid extract, then adding the filler into the traditional Chinese
medicine fluid extract, stirring to form a soft material, passing the soft material through a swinging granulator, and
drying to obtain a
medicine-containing
pill core; and putting the
pill cores into a
fluidized bed, laterally spraying the slow-release
coating solution,
drying, and sieving to prepare the slow-release granules. The prepared traditional Chinese
medicine formula sustained-release granules can release 90% or above within 8-10 hours, have a good constant-speed sustained-release characteristic, can meet the clinical requirement of 1-2 times of administration every day, and have good clinical application prospects and market value.