287 results about "Corydalis" patented technology

The invention discloses a traditional Chinese medicine composition for treating skin diseases and a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 6-12 parts of radix notoginseng, 8-15 parts of radix salviae miltiorrhizae, 10-20 parts of rhizoma chuanxiong, 8-15 parts of rhizoma curcumae longae, 15-35 parts of radix angelicae sinensis, 3-8 parts of sandalwood, 3-8 parts of fructus aurantii immaturus, 40-60 parts of ramulus cinnamomi, 8-15 parts of rhizoma corydalis, 8-15 parts of rhizoma curcumae, 2-5 parts of flos carthami, 5-12 parts of radix puerariae, 8-15 parts of radix rehmanniae, 3-8 parts of pericarpium citri reticulatae and 8-15 parts of spica prunellae. The traditional Chinese medicine composition is prepared from 3-8 parts of radix trichosanthis, 15-35 parts of tribulus terrestris, 15-35 parts of cicada slough, 5-12 parts of stiff silkworm and 8-15 parts of rhizoma drynariae. According to a multi-target collaborative mechanism, network pharmacology proves that 12 pathological pathways such as IL-17A and the like can be regulated and controlled, and the TNF-alpha inhibition rate is 89% and the barrier repair speed is increased by 2.3 times through key component combination. According to a transdermal synergistic technology, the specific surface area of the medicine reaches 8.5 m < 2 > / g through superfine grinding, a Franz test shows that the penetration amount of tanshinone is increased by 3.7 times, and the onset time is shortened to 8.3 minutes. Dual scar regulation and control: the thickness of scars in 12 weeks is reduced by half through TGF-beta3 up-regulation and alpha-SMA inhibition, and the collagen order degree is improved by 3.2 times.

The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for relieving pain, promoting blood circulation, diminishing swelling and removing blood stasis, application thereof and a blood stasis dispersing and pain relieving patch. The invention provides a traditional Chinese medicine composition for relieving pain, activating blood, diminishing swelling and removing stasis. The traditional Chinese medicine composition comprises the following components: lycopodium clavatum, radix clematidis, asarum, gentiana macrophylla, radix angelicae, rheum officinale, notopterygium root, roasted herba epimedii, radix achyranthis bidentatae, peach kernel, radix angelicae pubescentis, vinegar-processed rhizoma corydalis, vinegar-processed rhizoma cyperi, moutan bark, prepared kusnezoff monkshood root, prepared monkshood, vinegar-processed frankincense, Sinkiang lithospermum, vinegar-processed myrrh and sanguisorba officinalis. The blood stasis dispersing and pain relieving patch has the advantages of being good in curative effect, quick in effect taking, convenient to use, safe and reliable, can be used for treating traumatic injuries and pain caused by cervical spondylosis, scapulohumeral periarthritis, lumbar disc herniation, lumbar vertebrae hyperosteogeny, spinal stenosis, sciatica, ankylosing spondylitis, arthritis and other diseases, and can achieve the effect of treating both symptoms and root causes.

The present invention provides a composite insecticide containing plant extracts and its preparation process, belonging to the technical field of pesticide preparation; the preparation process includes the following steps: preparing a composite carrier powder; preparing a modified composite carrier powder; preparing a Corydalis extract; preparing a composite insecticide. By first dispersing nano-calcium carbonate powder in deionized water, then adding a mixed solution of calcium nitrate solution and diammonium hydrogen phosphate solution, and carrying out a hydrothermal reaction to prepare a composite carrier powder of nano-calcium carbonate and hydroxyapatite, after loading the Corydalis extract and veratridine with this composite carrier powder, the prepared composite insecticide can have a slow-release effect, extend the insecticidal action time, reduce the number of pesticide applications, and reduce environmental pollution. In addition, after modifying the composite carrier powder, its loading rate for the Corydalis extract and veratridine can be improved, thereby enhancing the insecticidal effect of the composite insecticide.

The invention discloses a traditional Chinese medicine composition for diabetic foot ulcer and a preparation method thereof. Comprising effective extracts of folium ginkgo, radix astragali, rhizoma corydalis and rhizoma anemones raddeanae as active pharmaceutical ingredients. The traditional Chinese medicine composition has an obvious improvement effect on diabetic foot ulcer, the cure rate of a rat with the diabetic foot ulcer can be obviously increased, wound healing is accelerated, and the action mechanism of the traditional Chinese medicine composition is closely related to a Wnt / beta-catenin signal channel. In addition, the traditional Chinese medicine composition provided by the invention also has the advantages of simplicity in preparation, low cost, convenience in carrying and remarkable effect.

The invention discloses a traditional Chinese medicine composition for treating chronic pelvic inflammation, which is prepared from the following raw materials: 8-16 parts of fried radix bupleuri, 8-16 parts of white peony root, 20-40 parts of astragalus membranaceus, 20-40 parts of radix pseudostellariae, 10-20 parts of poria cocos, 10-20 parts of bighead atractylodes rhizome, 10-20 parts of angelica sinensis, 8-16 parts of ligusticum wallichii, 8-16 parts of mint, 8-16 parts of rhizoma cyperi, 8-16 parts of corydalis tuber, 8-16 parts of fried endothelium corneum gigeriae galli, 8-16 parts of salvia miltiorrhiza, 8-16 parts of sargentgloryvine stem, 8-16 parts of patrinia and 4-8 parts of liquorice. The traditional Chinese medicine is especially suitable for treating qi deficiency and blood stasis type chronic pelvic inflammation.

The invention belongs to the technical field of traditional Chinese medicines, and provides an external traditional Chinese medicine composition for tendon injury, blood stasis, swelling and pain and bone impediment. The traditional Chinese medicine composition comprises the following components: prepared kusnezoff monkshood root, lycopodium clavatum, garden burnet, rheum officinale, radix clematidis, ligusticum wallichii, rhizoma zingiberis, angelica sinensis, Sinkiang lithospermum, peach kernel, fried gardenia, turmeric, radix angelicae pubescentis, asarum, notopterygium root, sappan wood, red paeony root, garden balsam stem, vinegar frankincense, vinegar corydalis tuber, vinegar myrrh, vinegar rhizoma cyperi, bran-fried fructus aurantii and golden cypress. The invention further discloses a preparation method and application of the traditional Chinese medicine composition for tendon injury, blood stasis, swelling and pain and bone impediment. The traditional Chinese medicines perform respective functions in monarch, minister, assistant and guide, the whole formula has the effects of promoting blood circulation to remove blood stasis, activating meridians to stop pain, dispelling wind and eliminating dampness, and reducing swelling and removing stasis, a synergistic treatment effect on tendon injury, blood stasis, swelling and pain and bone impediment is formed through a multi-target-point synergistic effect, the limitation that a traditional Chinese medicine with a single effect is difficult to comprehensively deal with is solved, and the effect of treating both symptoms and root causes is achieved; the traditional Chinese medicine composition has remarkable social benefits and clinical application value.

The invention relates to the technical field of traditional Chinese medicine compositions, and discloses a traditional Chinese medicine composition for wound healing and a preparation method thereof.The traditional Chinese medicine composition used in the early stage comprises 10-12 parts of rheum officinale, 5-6 parts of coptis chinensis, 10-12 parts of scutellaria baicalensis, 10-12 parts of golden cypress, 10-12 parts of corydalis tuber, 6-7 parts of pseudo-ginseng, 5-6 parts of pollen typhae, 4-5 parts of dragon's blood, 10-12 parts of sanguisorba officinalis, 10-13 parts of ramulus mori and 10-12 parts of gallnut; the traditional Chinese medicine composition used in the middle stage is prepared from 10-12 parts of radix astragali, 10-12 parts of radix angelicae sinensis, 10-12 parts of radix salviae miltiorrhizae, 10-12 parts of talc, 10-12 parts of ramulus mori, 10-12 parts of gallnut, 10-12 parts of rhizoma chuanxiong, 4-5 parts of resina draconis, 10-12 parts of frankincense and 10-12 parts of myrrh; the traditional Chinese medicine composition used in the later period comprises 10-12 parts of radix astragali, 10-12 parts of radix dipsaci, 10-12 parts of radix angelicae sinensis, 10-12 parts of rhizoma chuanxiong, 10-12 parts of gallnut, 10-12 parts of ramulus mori, 10-12 parts of radix codonopsis, 10-12 parts of radix salviae miltiorrhizae, 10-12 parts of radix morindae officinalis and 10-12 parts of talc. Wound treatment is divided into three stages, the cure rate of chronic refractory wounds (CRW) can be remarkably increased, inflammatory factors are inhibited, and tissue regeneration is promoted.

The invention discloses a traditional Chinese medicine compound preparation for treating insomnia and a preparation method thereof, the traditional Chinese medicine compound preparation is prepared from the following raw materials or alcohol and water of the following raw materials or water extract or honey-processed paste: 15-30g of lily, 15-30g of lucid ganoderma, 15-90g of vine of multiflower knotweed, 30-60g of cortex albiziae, 30-60g of nacre mother of pearl, 6-15g of coptis chinensis, 15-30g of spina date seed, 30-60g of poria with hostwood, 6-15g of polygala tenuifolia and 30-60g of magnetite. The preparation method comprises the following steps: uniformly mixing 30-60 g of lapis chloriti, 30-60 g of ligusticum wallichii, 10-15 g of schisandra chinensis, 3-10 g of cinnamon, 15-30 g of salvia miltiorrhiza, 30-60 g of oyster, 15-30 g of platycladi seed, 15-30 g of corydalis tuber and 15-30 g of rhizoma anemarrhenae with alcohol or water or refining honey to prepare paste, and preparing the paste into a required dosage form. The traditional Chinese medicine composition has the beneficial effects that after scientific and reasonable compatibility and preparation, the medicine effect has a synergistic effect, and the traditional Chinese medicine composition has the effects of nourishing yin, clearing heat, calming the heart and soothing the nerves and is used for treating insomnia caused by fire excess from yin deficiency and liver depression.

The invention provides a traditional Chinese medicine preparation for treating chronic prostatitis, and relates to the technical field of traditional Chinese medicine pharmacy. The traditional Chinese medicine preparation is prepared from black nightshade, hypericum perforatum, yam rhizome, rhizoma sparganii, common sage herb, chingma abutilon seed, polyporus umbellatus, uniflower swisscentaury root, corydalis amabilis, aspongopus, glossy privet fruit, fructus broussonetiae, radix ophiopogonis, tuber fleeceflower stem, day lily and liquorice. The traditional Chinese medicine preparation has the effects of clearing heat and promoting diuresis, promoting blood circulation to remove blood stasis, nourishing yin and soothing nerves and tonifying liver and kidney. The traditional Chinese medicine preparation disclosed by the invention has a remarkable treatment effect on CNP rats, and the prostate pathological injury condition and inflammatory response of the CNP rats are effectively relieved. In addition, the traditional Chinese medicine composition has a good treatment effect on relieving pain, frequent micturition, urgent urination, dysuria and other clinical symptoms and inflammation conditions of patients, and has a high total treatment effective rate on chronic prostatitis. The traditional Chinese medicine preparation provides a new scheme for treating chronic prostate.

The invention discloses an establishment method of an HPLC (high performance liquid chromatography) characteristic chromatogram of granules for treating common cold and clearing heat and a component content test thereof, and belongs to the technical field of pharmaceutical analys.According to the research, the HPLC characteristic chromatogram of the granules for treating common cold and clearing heat is established under the same chromatographic condition by adopting a high performance liquid chromatography, and the overall internal quality in a preparation is comprehensively reflected; the method for simultaneously determining the content of amygdalin, puerarin, cimicifugin and corydalis bungeana is established, methodology verifies that the method is simple, convenient and feasible, has good stability and repeatability, and can be used for detection in production process monitoring and quality evaluation of the cold and heat clearing granules to ensure that the quality of the cold and heat clearing granules meets the standard. The scheme not only scientifically restores the overall pharmacodynamic material basis of the compound preparation, but also provides a new generalizable normal form for quality control of traditional Chinese medicines with the advantages of low cost and high efficiency, and has milestone significance for promoting industry standardization and internationalization.

The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine application for relieving neck-shoulder and lumbocrural pain and a preparation method thereof. The traditional Chinese medicine application is prepared from, by mass, 15-50 g of obscured homalomena rhizome, 15-50 g of cortex illicii, 15-50 g of herba lycopodii, 15-50 g of rhizoma curcumae longae, 15-50 g of rhizoma corydalis, 15-50 g of radix puerariae, 15-50 g of garden balsam stem, 15-50 g of radix saposhnikoviae, 15-50 g of flos carthami, 15-50 g of radix cyathulae, 15-50 g of rhizoma seu radix notopterygii, 15-50 g of radix angelicae pubescentis, 15-50 g of lumbricus, 15-20 g of frankincense, 15-20 g of myrrh and 20-30 g of radix clematidis. Compared with traditional medicine application with a single effect, the traditional Chinese medicine application has the advantages that the pain relieving effect is quicker, the symptom improvement is more thorough, meanwhile, the application range of treating the neck, shoulder, waist and leg pain is expanded, and a patient can operate the traditional Chinese medicine application at home without assistance of professional medical equipment.

The invention relates to the technical field of seedling raising devices, in particular to a seedling raising device and method for promoting the germination rate of cnidium monnieri seeds. The seedling raising device comprises a seedling raising box, and the inner wall of the seedling raising box is provided with a reset rack and a starting rack which are distributed in parallel up and down and incline downwards; an inclined upward guide groove is formed in the inner wall, located above the reset rack, of the seedling raising box, and a tooth locking block is inserted into the guide groove in a sliding mode. By arranging the soil loosening mechanism, when a substrate is dry, a sleeve drives a harrow wheel to rotate, so that the harrow wheel slides along with a sliding seat while rotating, the effect of punching holes in the substrate on a seedling raising plate is achieved, the situation that water cannot permeate due to substrate hardening is avoided, when the humidity of the substrate is high, a gear is locked by a gear locking block, and the soil loosening effect is good. Therefore, the harrow wheel on the sleeve drives the harrow nails to slide along with the sliding seat without rotating, then the harrow nails can turn over the substrate, the air permeability of the substrate is improved, and meanwhile water loss is accelerated.

The invention discloses a traditional Chinese medicine composition for treating acute gout, an external gel and a preparation method thereof, and the traditional Chinese medicine composition comprises the following raw material components in parts by mass: 5-20 parts of radix clematidis, 5-20 parts of polygonum cuspidatum, 5-20 parts of honeysuckle stem, 5-15 parts of radix aconiti preparata, 5-15 parts of pine nodular branch, 1-5 parts of corydalis tuber and 1-3 parts of asarum. The gel disclosed by the invention is an external gel prepared by researching through a traditional Chinese medicine composition intermediate extraction process and a preparation forming process, has the effective effects of directly reaching an affected part, taking effect quickly, being good in patient compliance and the like, and can realize industrial production through pilot scale-up experiment verification. Animal experiment research results show that the radix clematidis pain-relieving gel has remarkable anti-inflammatory and pain-relieving effects.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to an external traditional Chinese medicine ointment for treating acute gouty arthritis and a preparation method thereof. Comprising the following components in parts by mass: 18-22 parts of rheum officinale, 20-26 parts of turmeric, 15-19 parts of cortex phellodendri, 15-19 parts of indigo naturalis, 15-19 parts of rhizoma smilacis glabrae, 14-18 parts of radix clematidis, 14-18 parts of moutan bark, 14-18 parts of herba lycopi, 10-14 parts of semen plantaginis, 8-12 parts of radix stephaniae tetrandrae, 8-12 parts of rhizoma corydalis and 5-9 parts of liquorice. The ointment not only aims at inflammation and pain in the acute stage of gout, but also promotes uric acid excretion through medicines such as rhizoma smilacis glabrae and semen plantaginis, and has a certain auxiliary uric acid reduction effect. The compound design of the traditional Chinese medicine composition integrates the functions of clearing heat and promoting diuresis and promoting blood circulation to remove blood stasis, body metabolism is regulated from multiple targets, symptoms are relieved, pathogenesis conditioning is also considered, and a more comprehensive solution is provided for treatment of gouty arthritis.

The invention relates to the technical field of traditional Chinese medicines, and discloses an external traditional Chinese medicine formula for treating arthralgia with syndrome of cold-dampness obstruction, which comprises the following ingredients: 10g of cassia twig, 6g of dried ginger, 12g of lycopodium clavatum, 12g of herba lycopi, 10g of notopterygium root, 10g of radix angelicae pubescentis, 9g of loose knot, 9g of semen brassicae, 10g of rhizoma corydalis, 15g of caulis spatholobi and 10g of cortex acanthopanacis. According to the external traditional Chinese medicine formula for treating the cold-dampness arthralgia, through accurate compatibility of medicinal materials with effects of warming and dispelling cold and dampness, promoting blood circulation to remove meridian obstruction and strengthening tendons and bones, a synergistic treatment system of warming and dredging, eliminating dampness, dredging collaterals and protecting bones is formed, so that symptoms such as joint crymodynia, stiffness and the like can be quickly relieved, cold-dampness evil can be eliminated from the pathogenesis level, and qi and blood circulation of joints can be improved; by adopting a standard processing technology and an optimized preparation method, the transdermal efficiency is improved while the irritation of the medicinal materials is reduced, the medicine can directly reach the focus, the gastrointestinal tract side effect caused by oral administration is avoided, and the traditional Chinese medicine composition is particularly suitable for middle-aged and elderly people and cold-dampness blockage type arthralgia patients with poor liver and kidney functions and sensitive skin.

The application belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating abdominal distension and diarrhea of cold-heat complex type and a preparation method thereof. The technical scheme points of the traditional Chinese medicine composition are as follows: the traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 3-6 parts of perilla, 3-10 parts of dried ginger, 3-12 parts of eucommia, 3-10 parts of scrophularia, 2-6 parts of coptis, 10-20 parts of fried coix seed, 6-10 parts of clear pinellia, 3-10 parts of dried tangerine or orange peel, 10-15 parts of poria, 6-10 parts of wheat-cooked atractylodes, 6-10 parts of vinegar-cured corydalis, 6-10 parts of vinegar-cured bupleurum, 6-10 parts of pericarpium zephyritae, 6-10 parts of chuanxiong, 6-10 parts of magnolia officinalis, 6-10 parts of fried hawthorn fruit, 3-6 parts of platycodon, and 3-10 parts of fried licorice. The traditional Chinese medicine composition and the traditional Chinese medicine water pill prepared from the traditional Chinese medicine composition have the effect of treating abdominal distension and diarrhea of cold-heat complex type.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to stasis-removing and pain-relieving pills and a quality detection method thereof. The stasis-removing and pain-relieving pill is prepared by taking radix paeoniae alba, rhizoma corydalis, radix paeoniae rubra, angelica sinensis, ligusticum wallichii, rhizoma cyperi, rhizoma zingiberis, fennel and astragalus membranaceus as raw materials and taking 10% starch slurry as an adhesive. The quality detection method of the stasis-removing and pain-relieving pill comprises general inspection, microscopic identification and thin-layer chromatography identification. And high performance liquid chromatography content determination. According to the present invention, by researching the preparation process and the quality standard of the stasis removing and pain relieving pill, the new thought and the new method are provided for the development of the traditional Chinese medicine preparation, the excellent choice is hopefully provided for the common gynecologic symptoms such as irregular menstruation, dysmenorrhea, postpartum blood stasis abdominal pain and the like, and the pain caused by the illness is relieved.

The invention relates to the field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for treating chronic prostatitis and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 5-15 parts of pericarpium citri reticulatae viride; 5-15 parts of szechwan chinaberry fruit; 5-15 parts of the root of three-nerved spicebush; 5-15 parts of radix angelicae dahuricae; 10-20 parts of herba lycopi; 10 to 20 parts of herba patriniae; 4 to 8 parts of frankincense; 4 to 8 parts of myrrh; 5 to 15 parts of rhizoma corydalis; 10 to 20 parts of caulis spatholobi; 5 to 15 parts of diverse wormwood herb; 10 to 20 parts of cowherb seed; 5-15 parts of radix curcumae; and 4-8 parts of fennel. The traditional Chinese medicine composition can significantly improve the symptoms of chronic prostatitis, regulate the syndromes of traditional Chinese medicine and improve the life quality of patients, and has good safety and patient compliance.

The invention belongs to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine preparation for treating peptic ulcer and a preparation method thereof. The traditional Chinese medicine preparation is prepared from the following components in parts by weight: 10 to 15 parts of cassia twig, 10 to 20 parts of radix paeoniae alba, 10 to 20 parts of radix salviae miltiorrhizae, 8 to 12 parts of rhizoma cyperi, 4 to 8 parts of rhizoma chuanxiong, 25 to 35 parts of rhizoma corydalis, 10 to 20 parts of herba artemisiae scopariae, 25 to 35 parts of cortex magnoliae officinalis, 8 to 12 parts of caulis perillae and 2 to 4 parts of liquorice root. According to the invention, theories of dialectical treatment, holism concept and the like are reasonably applied, the compatibility is scientific and reasonable, the prescription is simplified, the preparation process is simple, the efficacy is accurate, the clinical applicability is strong, and the efficacy on peptic ulcer is exact. The traditional Chinese medicine preparation is an innovation of medicines for treating peptic ulcer, and has remarkable economic and social benefits.

The invention belongs to the technical field of drenching medicine bags, and particularly relates to a drenching medicine bag, which is prepared from the following raw materials in parts by weight: 8 to 12 parts of radix angelicae sinensis, 8 to 12 parts of myrrh, 13 to 17 parts of garden balsam stem, 8 to 12 parts of cortex eucommiae, 8 to 12 parts of radix salviae miltiorrhizae, 18 to 22 parts of caulis spatholobi, 8 to 12 parts of cortex cinnamomi, 8 to 12 parts of radix achyranthis bidentatae, 13 to 17 parts of rhizoma corydalis and 13 to 17 parts of herba lycopodii. The medicine bags are packaged by breathable non-woven fabrics, the amount of mixed medicine powder contained in each medicine bag is consistent with the total weight part of the raw materials in the claim 1, and the size of each medicine bag is 15-25 cm * 10 <-20 > cm. The drenching medicine bag is reasonable in formula, high in effective component dissolution rate and stable in quality, and meanwhile the standardized preparation method of the drenching medicine bag is provided so as to improve the application effect of drenching therapy.

The invention discloses a traditional Chinese medicine composition for treating chronic atrophic gastritis. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 20 parts of radix codonopsis, 10 to 20 parts of rhizoma atractylodis macrocephalae, 10 to 15 parts of poria cocos, 10 to 12 parts of pericarpium citri reticulatae, 6 to 10 parts of rhizoma pinellinae praeparata, 10 to 12 parts of radix aucklandiae, 10 to 12 parts of rhizoma corydalis, 3 to 6 parts of radix notoginseng, 10 to 12 parts of fructus aurantii immaturus, 10 to 20 parts of radix ginseng rubra, 15 to 30 parts of herba hedyotidis diffusae, 15 to 30 parts of semen coicis, 10 to 15 parts of rhizoma curcumae, 10 to 20 parts of radix salviae miltiorrhizae, 10 to 20 parts of radix astragali seu hedysari and 3 to 6 parts of liquorice root. The invention further discloses a preparation method of the traditional Chinese medicine composition. The traditional Chinese medicine composition aims at chronic atrophic gastritis with pathological characteristics of gastric mucosa dysplasia and intestinal metaplasia, and is remarkable in curative effect and small in side effect through reasonable medicine compatibility.

The present invention relates to a method for cultivating transgenic plants having increased anthocyanin content and enhanced tolerance to biotic and abiotic stress environments. The method comprises transferring a bHLH35 gene into recipient plants using a genetic engineering transformation method, to obtain transgenic plants having increased anthocyanin content and tolerance to biotic and abiotic stress environments. The bHLH35 gene may be selected from a ChbHLH35 gene from Corydalis hemidicentra or an AtbHLH35 gene from Arabidopsis thaliana.

The present invention discloses SSR molecular markers associated with the fresh weight trait of Corydalis bulbocapniodes sub-bulbs, their primers and applications, belonging to the technical field of molecular genetics. The SSR molecular markers associated with the fresh weight trait of Corydalis bulbocapniodes sub-bulbs disclosed by the present invention have amplification primer sequences as shown in SEQ ID NO.1 and 2. The SSR molecular markers associated with the fresh weight trait of Corydalis bulbocapniodes sub-bulbs and their amplification primers can be applied to the population structure analysis of Corydalis bulbocapniodes, the analysis of markers associated with the fresh weight trait of Corydalis bulbocapniodes sub-bulbs, the selection of excellent germplasms of Corydalis bulbocapniodes and the preparation of a kit for screening excellent germplasms of Corydalis bulbocapniodes with high sub-bulb weight, and can be directly used for screening excellent germplasms, gene mapping and cloning, and molecular marker-assisted breeding. Moreover, they have chromosome mapping information, which is beneficial to further fine mapping and cloning of genes controlling the fresh weight trait of sub-bulbs, and is of great significance in the breeding of high-yield Corydalis bulbocapniodes.

A preparation method of the wine comprises the following steps: 1) weighing the following raw materials in parts by weight: 18-22 parts of raw radix astragali, 13-17 parts of rhizoma drynariae, 13-17 parts of dog bone, 1-5 parts of semen strychni, 1 part of ginseng, 13-17 parts of herba epimedii, 13-17 parts of caulis spatholobi, 3-7 parts of gecko, 1 part of radix salviae miltiorrhizae, 3-7 parts of rhizoma corydalis, 1-5 parts of asarum heterotropoides, 1 part of gynostemma pentaphylla and 3-7 parts of chili; and 2) processing the raw materials into powder, placing the powder in a pottery clay jar, soaking the powder in 50-degree grain white spirit for more than half a year, performing high-temperature fermentation in summer, leaching the liquid medicine, and removing medicine residues to obtain the finished product of the fermented wine for rheumatic bone impediment. The traditional Chinese medicine has the advantages that the traditional Chinese medicine is reasonable in raw material design and convenient to prepare, has a good effect on treating various arthritis such as rheumatism, ankylosing spondylitis, rheumatic arthritis, lumbar disc herniation and hyperostosis, and has a very good popularization prospect and a very good medical economic value.

The invention discloses an internal and external compound medicine for treating gout, which comprises an oral medicament and an external medicament, the oral medicament is prepared by taking a first pharmaceutical composition as a raw material, the external medicament is prepared by taking a second pharmaceutical composition as a raw material, and the first pharmaceutical composition is prepared from herba lycopi, rhizoma alismatis, chicory and lily; the second pharmaceutical composition is prepared from the following components in parts by weight: radix aconiti preparata, rhizoma arisaematis preparata, ligusticum wallichii, caulis spatholobi and rhizoma corydalis. According to the traditional Chinese medicine composition, internal and external treatment is achieved through the oral medicament and the external medicament, the synergistic effect of the oral medicament and the external medicament can not only achieve the purpose of treating symptoms in emergency but also take'benefit 'as attack, especially for acute gout, symptoms of patients can be rapidly improved and relieved, the pain of the patients is relieved, and both symptoms and root causes are treated through different targets and multiple ways.

The application discloses a traditional Chinese medicine for treating contusion and injury, postoperative swelling and pain, and early swelling and pain of broken tendon and bone injury, which is configured from angelica sinensis, ligusticum chuanxiong, red peony root, prepared rehmannia, persicae semen, safflower, costus, fructus aurantii, panax notoginseng, poria cocos, alisma orientalis, astragalus membranaceus and rhizoma corydalis. The medicine is prepared according to the traditional Chinese medicine dialectical theory, has the effects of activating blood and resolving stasis, eliminating swelling and relieving pain, has reasonable formula, simple manufacturing process, remarkable curative effect, convenient use and moderate price, and is an effective prescription for treating tendon and bone pain in traditional Chinese medicine.

The invention discloses a formula and a preparation method of a quick-acting analgesic tincture external spraying agent, and belongs to the technical field of external spraying agents, the quick-acting analgesic tincture external spraying agent comprises the following raw materials in parts by weight: a group A: 25kg of radix clematidis, 20kg of radix saposhnikoviae, 20kg of rhizoma zingiberis, 20kg of radix angelicae, 20kg of rhizoma drynariae, 20kg of notopterygium root, 15kg of corydalis tuber, 15kg of radix aconiti preparata, 15kg of radix aconiti kusnezoffii preparata and 15kg of frankincense preparata; the traditional Chinese medicine is prepared from 15 kilograms of prepared myrrh, 15 kilograms of ligusticum wallichii, 10 kilograms of ephedra, 10 kilograms of asarum, 5 kilograms of saffron crocus (240 kilograms of 15 parts) and 1200 kilograms of ethanol. The group B comprises 15 kilograms of camphor, 5 kilograms of storax oil, 3 kilograms of vanillyl butyl ether and ethanol (the dosage is 300-900% of the total weight of the medicines), the prepared'ten-full-pain quick-napping 'tincture is generally used for various arthralgia pains caused by wind-cold-dampness stasis, and aims at the etiology and symptoms of arthralgia, cold-dampness pains, blood stasis pains, spasm pains and wind-excess channeling pains, medicine symptoms are combined, both symptoms and root causes are taken into consideration, and the traditional Chinese medicine tincture can be used for treating various arthralgia pains caused by wind-cold-dampness stasis. The composition has the advantages of quick transdermal effect, quick effect, broad effect, special effect, safety and convenience, and meets the fast-paced life of modern people and the high requirements on health, high efficiency, convenience and safety. The promotion and popularization of the invention will surely produce great social and economic benefits.

The present invention relates to a pharmaceutical composition for treating chronic glomerulonephritis, its preparation method and application. The pharmaceutical composition is composed of Rhizoma Smilacis Glabrae Albae, Flos Abelmoschi Manihot, Herba Ephedrae Delavayi, Radix Saposhnikoviae Divaricatae, Ramulus Ulmi Pumilae, Herba Dichondrae Repentis, Rhizoma Corydalis Saxicolae, Radix Salviae Yunnanensis, and Radix Achyranthis Aspera. The preparation method is to first extract the above nine herbs with ethanol and then with water, and the mixed solution is concentrated to make a pharmaceutical preparation. The combined use of this pharmaceutical preparation and western medicine can improve the treatment effect of chronic glomerulonephritis, with a total effective rate reaching 84%. Moreover, it can significantly reduce the urinary protein and red blood cells in patients, showing a significant difference compared with the control group using western medicine alone. This indicates that it can effectively improve the clinical symptoms of patients, has no adverse reactions, has high safety, and has extremely high popularization value.

The invention relates to the technical field of physical therapy products, in particular to a traditional Chinese medicine composition for treating muscle fascia injury and a special muscle effect patch structure. The traditional Chinese medicine composition comprises the following raw materials: premna fulva, safflower, corydalis tuber, garden balsam stem, corydalis amabilis, lycopodium clavatum, ground beetle, cassia twig, borneol and white spirit. The special muscle effect patch structure comprises a fixing area and a cross-shaped structure formed by connecting four anchoring parts, the anchoring parts are connected with the fixing area, a medicine ball is connected to the center of the fixing area, and a plurality of medicine outlet holes are formed in the wall face of the medicine ball with liquid absorption filler inside. The surface of the targeting part is provided with a bonding layer used for being adhered to the skin, the bonding layer is connected with release paper, and the release paper is provided with a protruding film matched with the medicine balls. Through the unique structural design and cooperation of the fixing area, the anchoring part, the targeting part, the medicine ball and the like, muscles are relaxed in a physical mode, dynamic and active medicine permeation and physical pressing are achieved, and the pressing and rebounding effects of manual massage are simulated, so that transdermal delivery of medicine components is better achieved.