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113 results about "Corydalis" patented technology

Corydalis (Greek korydalís "crested lark") is a genus of about 470 species of annual and perennial herbaceous plants in the Papaveraceae family, native to the temperate Northern Hemisphere and the high mountains of tropical eastern Africa. They are most diverse in China and the Himalayas, with at least 357 species in China.

External traditional Chinese medicine composition for tendon injury, blood stasis, swelling and pain and bone impediment

The invention belongs to the technical field of traditional Chinese medicines, and provides an external traditional Chinese medicine composition for tendon injury, blood stasis, swelling and pain and bone impediment. The traditional Chinese medicine composition comprises the following components: prepared kusnezoff monkshood root, lycopodium clavatum, garden burnet, rheum officinale, radix clematidis, ligusticum wallichii, rhizoma zingiberis, angelica sinensis, Sinkiang lithospermum, peach kernel, fried gardenia, turmeric, radix angelicae pubescentis, asarum, notopterygium root, sappan wood, red paeony root, garden balsam stem, vinegar frankincense, vinegar corydalis tuber, vinegar myrrh, vinegar rhizoma cyperi, bran-fried fructus aurantii and golden cypress. The invention further discloses a preparation method and application of the traditional Chinese medicine composition for tendon injury, blood stasis, swelling and pain and bone impediment. The traditional Chinese medicines perform respective functions in monarch, minister, assistant and guide, the whole formula has the effects of promoting blood circulation to remove blood stasis, activating meridians to stop pain, dispelling wind and eliminating dampness, and reducing swelling and removing stasis, a synergistic treatment effect on tendon injury, blood stasis, swelling and pain and bone impediment is formed through a multi-target-point synergistic effect, the limitation that a traditional Chinese medicine with a single effect is difficult to comprehensively deal with is solved, and the effect of treating both symptoms and root causes is achieved; the traditional Chinese medicine composition has remarkable social benefits and clinical application value.
Owner:TIANJIN INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE HOSPITAL (TIANJIN NANKAI HOSPITAL)

Traditional Chinese medicine preparation for treating chronic prostatitis

The invention provides a traditional Chinese medicine preparation for treating chronic prostatitis, and relates to the technical field of traditional Chinese medicine pharmacy. The traditional Chinese medicine preparation is prepared from black nightshade, hypericum perforatum, yam rhizome, rhizoma sparganii, common sage herb, chingma abutilon seed, polyporus umbellatus, uniflower swisscentaury root, corydalis amabilis, aspongopus, glossy privet fruit, fructus broussonetiae, radix ophiopogonis, tuber fleeceflower stem, day lily and liquorice. The traditional Chinese medicine preparation has the effects of clearing heat and promoting diuresis, promoting blood circulation to remove blood stasis, nourishing yin and soothing nerves and tonifying liver and kidney. The traditional Chinese medicine preparation disclosed by the invention has a remarkable treatment effect on CNP rats, and the prostate pathological injury condition and inflammatory response of the CNP rats are effectively relieved. In addition, the traditional Chinese medicine composition has a good treatment effect on relieving pain, frequent micturition, urgent urination, dysuria and other clinical symptoms and inflammation conditions of patients, and has a high total treatment effective rate on chronic prostatitis. The traditional Chinese medicine preparation provides a new scheme for treating chronic prostate.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV

Traditional Chinese medicine composition for treating acute gout, external gel and preparation method thereof

PendingCN121796471AAerosol deliverySkeletal disorderAcute goutAnimal testing
The invention discloses a traditional Chinese medicine composition for treating acute gout, an external gel and a preparation method thereof, and the traditional Chinese medicine composition comprises the following raw material components in parts by mass: 5-20 parts of radix clematidis, 5-20 parts of polygonum cuspidatum, 5-20 parts of honeysuckle stem, 5-15 parts of radix aconiti preparata, 5-15 parts of pine nodular branch, 1-5 parts of corydalis tuber and 1-3 parts of asarum. The gel disclosed by the invention is an external gel prepared by researching through a traditional Chinese medicine composition intermediate extraction process and a preparation forming process, has the effective effects of directly reaching an affected part, taking effect quickly, being good in patient compliance and the like, and can realize industrial production through pilot scale-up experiment verification. Animal experiment research results show that the radix clematidis pain-relieving gel has remarkable anti-inflammatory and pain-relieving effects.
Owner:SUZHOU UNIV

External traditional Chinese medicine ointment for treating acute gouty arthritis and preparation method thereof

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to an external traditional Chinese medicine ointment for treating acute gouty arthritis and a preparation method thereof. Comprising the following components in parts by mass: 18-22 parts of rheum officinale, 20-26 parts of turmeric, 15-19 parts of cortex phellodendri, 15-19 parts of indigo naturalis, 15-19 parts of rhizoma smilacis glabrae, 14-18 parts of radix clematidis, 14-18 parts of moutan bark, 14-18 parts of herba lycopi, 10-14 parts of semen plantaginis, 8-12 parts of radix stephaniae tetrandrae, 8-12 parts of rhizoma corydalis and 5-9 parts of liquorice. The ointment not only aims at inflammation and pain in the acute stage of gout, but also promotes uric acid excretion through medicines such as rhizoma smilacis glabrae and semen plantaginis, and has a certain auxiliary uric acid reduction effect. The compound design of the traditional Chinese medicine composition integrates the functions of clearing heat and promoting diuresis and promoting blood circulation to remove blood stasis, body metabolism is regulated from multiple targets, symptoms are relieved, pathogenesis conditioning is also considered, and a more comprehensive solution is provided for treatment of gouty arthritis.
Owner:SHANGHAI SIXTH PEOPLES HOSPITAL JINSHAN BRANCH (JINSHAN DISTRICT CENT HOSPITAL AFFILIATED TO SHANGHAI HEALTH MEDICAL COLLEGE SHANGHAI JINSHAN DISTRICT CENT HOSPITAL)

A traditional Chinese medicine composition for treating abdominal distension and diarrhea with cold and heat symptoms and a preparation method thereof

The application belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating abdominal distension and diarrhea of cold-heat complex type and a preparation method thereof. The technical scheme points of the traditional Chinese medicine composition are as follows: the traditional Chinese medicine composition is composed of the following raw medicinal materials in parts by weight: 3-6 parts of perilla, 3-10 parts of dried ginger, 3-12 parts of eucommia, 3-10 parts of scrophularia, 2-6 parts of coptis, 10-20 parts of fried coix seed, 6-10 parts of clear pinellia, 3-10 parts of dried tangerine or orange peel, 10-15 parts of poria, 6-10 parts of wheat-cooked atractylodes, 6-10 parts of vinegar-cured corydalis, 6-10 parts of vinegar-cured bupleurum, 6-10 parts of pericarpium zephyritae, 6-10 parts of chuanxiong, 6-10 parts of magnolia officinalis, 6-10 parts of fried hawthorn fruit, 3-6 parts of platycodon, and 3-10 parts of fried licorice. The traditional Chinese medicine composition and the traditional Chinese medicine water pill prepared from the traditional Chinese medicine composition have the effect of treating abdominal distension and diarrhea of cold-heat complex type.
Owner:HULUNBEIER CHINA MONGOLIA HOSPITAL (HULUNBEIER CHINA MONGOLIA MEDICAL RES INST)

Stasis-removing and pain-relieving pill and quality detection method thereof

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to stasis-removing and pain-relieving pills and a quality detection method thereof. The stasis-removing and pain-relieving pill is prepared by taking radix paeoniae alba, rhizoma corydalis, radix paeoniae rubra, angelica sinensis, ligusticum wallichii, rhizoma cyperi, rhizoma zingiberis, fennel and astragalus membranaceus as raw materials and taking 10% starch slurry as an adhesive. The quality detection method of the stasis-removing and pain-relieving pill comprises general inspection, microscopic identification and thin-layer chromatography identification. And high performance liquid chromatography content determination. According to the present invention, by researching the preparation process and the quality standard of the stasis removing and pain relieving pill, the new thought and the new method are provided for the development of the traditional Chinese medicine preparation, the excellent choice is hopefully provided for the common gynecologic symptoms such as irregular menstruation, dysmenorrhea, postpartum blood stasis abdominal pain and the like, and the pain caused by the illness is relieved.
Owner:HEILONGJIANG UNIV OF CHINESE MEDICINE

Traditional Chinese medicine composition for treating chronic prostatitis and preparation method and application thereof

PendingCN121466239ADispersion deliveryUrinary disorderLycopus lucidusPatrinia
The invention relates to the field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for treating chronic prostatitis and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 5-15 parts of pericarpium citri reticulatae viride; 5-15 parts of szechwan chinaberry fruit; 5-15 parts of the root of three-nerved spicebush; 5-15 parts of radix angelicae dahuricae; 10-20 parts of herba lycopi; 10 to 20 parts of herba patriniae; 4 to 8 parts of frankincense; 4 to 8 parts of myrrh; 5 to 15 parts of rhizoma corydalis; 10 to 20 parts of caulis spatholobi; 5 to 15 parts of diverse wormwood herb; 10 to 20 parts of cowherb seed; 5-15 parts of radix curcumae; and 4-8 parts of fennel. The traditional Chinese medicine composition can significantly improve the symptoms of chronic prostatitis, regulate the syndromes of traditional Chinese medicine and improve the life quality of patients, and has good safety and patient compliance.
Owner:SHANGHAI SEVENTH PEOPLES HOSPITAL

Gene bHLH35 for promoting anthocyanin accumulation of plants and application thereof

The present invention relates to a method for cultivating transgenic plants having increased anthocyanin content and enhanced tolerance to biotic and abiotic stress environments. The method comprises transferring a bHLH35 gene into recipient plants using a genetic engineering transformation method, to obtain transgenic plants having increased anthocyanin content and tolerance to biotic and abiotic stress environments. The bHLH35 gene may be selected from a ChbHLH35 gene from Corydalis hemidicentra or an AtbHLH35 gene from Arabidopsis thaliana.
Owner:LANZHOU UNIV

A formula of a traditional Chinese medicine treatment of muscle and bone pain granules

The application discloses a traditional Chinese medicine for treating contusion and injury, postoperative swelling and pain, and early swelling and pain of broken tendon and bone injury, which is configured from angelica sinensis, ligusticum chuanxiong, red peony root, prepared rehmannia, persicae semen, safflower, costus, fructus aurantii, panax notoginseng, poria cocos, alisma orientalis, astragalus membranaceus and rhizoma corydalis. The medicine is prepared according to the traditional Chinese medicine dialectical theory, has the effects of activating blood and resolving stasis, eliminating swelling and relieving pain, has reasonable formula, simple manufacturing process, remarkable curative effect, convenient use and moderate price, and is an effective prescription for treating tendon and bone pain in traditional Chinese medicine.
Owner:赵珞

Traditional Chinese medicine composition for treating muscle fascia injury and special muscle effect patch structure

PendingCN121337900AAnthropod material medical ingredientsAntipyreticMuscle fasciaMuscular fascia
The invention relates to the technical field of physical therapy products, in particular to a traditional Chinese medicine composition for treating muscle fascia injury and a special muscle effect patch structure. The traditional Chinese medicine composition comprises the following raw materials: premna fulva, safflower, corydalis tuber, garden balsam stem, corydalis amabilis, lycopodium clavatum, ground beetle, cassia twig, borneol and white spirit. The special muscle effect patch structure comprises a fixing area and a cross-shaped structure formed by connecting four anchoring parts, the anchoring parts are connected with the fixing area, a medicine ball is connected to the center of the fixing area, and a plurality of medicine outlet holes are formed in the wall face of the medicine ball with liquid absorption filler inside. The surface of the targeting part is provided with a bonding layer used for being adhered to the skin, the bonding layer is connected with release paper, and the release paper is provided with a protruding film matched with the medicine balls. Through the unique structural design and cooperation of the fixing area, the anchoring part, the targeting part, the medicine ball and the like, muscles are relaxed in a physical mode, dynamic and active medicine permeation and physical pressing are achieved, and the pressing and rebounding effects of manual massage are simulated, so that transdermal delivery of medicine components is better achieved.
Owner:李登全

Traditional Chinese medicine composition for treating diarrhea-type irritable bowel syndrome

The invention relates to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating diarrhea-type irritable bowel syndrome. The traditional Chinese medicine composition comprises 4-16 g of codonopsis pilosula, 4-16 g of roasted rhizoma atractylodis macrocephalae, 3-12 g of fructus psoraleae, 2-8 g of galangal, 3-12 g of poria cocos, 4-16 g of white hyacinth bean, 2-8 g of elecampane, 3-12 g of corydalis tuber and 2-8 g of honey-fried licorice root. The traditional Chinese medicine composition provided by the invention has the effects of tonifying spleen, clearing damp, warming middle-jiao, stopping diarrhea and the like, and can obviously improve clinical symptoms of IBS-D patients and model animals, specifically, the clinical symptoms are improved, the water content of excrement is reduced, and visceral hypersensitivity is relieved.
Owner:SHENZHEN BAOAN DISTRICT TRADITIONAL CHINESE MEDICINE HOSPITAL

Application of total alkaloids of corydalis tomentosa in preparation of medicine for preventing and treating liver cancer

The invention belongs to the technical field of biological medicines, and particularly relates to application of total alkaloids of corydalis tomentosa in preparation of medicines for preventing and treating liver cancer. The corydalis tomentosa total alkaloid is prepared by the following steps: crushing a corydalis tomentosa medicinal material, performing reflux extraction, and sequentially performing filtration, concentration, impurity removal, pH adjustment, redissolution, filtration and freeze-drying treatment on the obtained extracting solution, thereby obtaining the corydalis tomentosa total alkaloid. The obtained corydalis tomentosa total alkaloid contains 10%-20% of dehydrocavidine, 0.6%-2% of coptisine and 1%-5% of methyl coptisine. According to the invention, the total alkaloids of corydalis tomentosa are separated and extracted, a mouse model bearing liver cancer H22 transplanted tumor is established, the tumor inhibition activity of the total alkaloids of corydalis tomentosa is evaluated, and the action mechanism of the total alkaloids of corydalis tomentosa is preliminarily discussed. The results show that the corydalis tomentosa total alkaloid not only has a remarkable tumor inhibition effect, but also can improve the immune level of mice, induce tumor cell apoptosis and regulate the level of cytokines, has small side effects on visceral organs, and has great application potential.
Owner:CHONGQING DRUG PLANTING RES INST

A qistagnation and blood stasis acupoint patch and a preparation method thereof

The present application relates to the technical field of Qizixuexu agent sticking, especially to a Qizixuexu acupoint sticking and a preparation method thereof, the Qizixuexu acupoint sticking comprises the following raw materials and weight parts, Anarhichas lupus, 3-7 parts; red peony root, 8-12 parts; peach kernel, 8-12 parts; gardenia, 8-12 parts; myrrh in vinegar, 8-12 parts; olibanum in vinegar, 8-12 parts; baizhi, 8-12 parts; sanqi, 8-12 parts; rhubarb, 8-12 parts; xiangfu, 8-12 parts; corydalis, 8-12 parts; safflower, 8-12 parts. The present application improves the Qizixuexu related symptoms of the elderly patients by preparing a specific Qizixuexu acupoint sticking, plays a role in multiple targets and multiple directions, and improves the treatment effect of the patients.
Owner:金小越

An external traditional Chinese medicine composition for treating thin endometrium

The present application relates to the field of traditional Chinese medicine, and specifically relates to a kind of external use traditional Chinese medicine composition for treating thin endometrium, which is composed of the following raw medicinal materials: cinnamon 250-300g, fennel 250-300g, Corydalis 250-480g, Cnidium 250-400g, safflower 250-300g, Evodia 150-200g, mugwort leaf 250-300g, and ginger juice 500-600ml.The external use combined medicine of the present application can obviously improve the symptoms of dysmenorrhea, little menstrual flow, dark red menstrual color, and more menstrual blood clots, thicken the endometrial thickness during ovulation, and improve the clinical pregnancy rate of patients with thin endometrium.The external use traditional Chinese medicine is absorbed through skin, does not burden liver and kidney functions, achieves the purposes of warming meridians, activating blood and resolving stasis through the action of acupoint meridian, has little side effects, and is convenient for promotion.
Owner:SHUGUANG HOSPITAL AFFILIATED WITH SHANGHAI UNIV OF T C M

Composition with function of preventing hair breakage as well as preparation method and application of composition

PendingCN122005379ACosmetic preparationsHair cosmeticsBiotechnologyPanax notoginseng root extract
The invention relates to the technical field of cosmetics, in particular to a composition with a hair breakage prevention function and a preparation method and application thereof. The composition consists of plant extracts and composite polypeptide, wherein the plant extracts comprise a pseudo-ginseng root extract, a cnidium monnieri fruit extract and a coralline algae extract; the composite polypeptide comprises tripeptide-2, acetyl tetrapeptide-3 and pentapeptide-3. The composition disclosed by the invention is applied to shampoo or hair conditioners, so that the tensile strength of hair can be improved, and hair breakage can be prevented.
Owner:GUANGDONG FADI COSMETICS TECH CO LTD +1

Compound preparation for treating osteoarthritis and preparation method thereof

The invention discloses a compound preparation for treating osteoarthritis and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations. Comprising the following raw materials in parts by weight: 15-19 parts of wine-processed radix achyranthis bidentatae, 13-15 parts of salted eucommia ulmoides, 11-13 parts of angelica sinensis, 9-11 parts of bran-fried rhizoma atractylodis, 11-13 parts of semen coicis, 5-7 parts of poria cocos, 4-6 parts of wine-processed flos carthami, 4-6 parts of vinegar-processed rhizoma corydalis, 4-6 parts of radix paeoniae alba, 8-10 parts of sand-scalded rhizoma drynariae and 4-6 parts of honey-fried liquorice. According to the compound preparation for treating osteoarthritis and the preparation method, arthralgia and stiffness can be rapidly relieved, long-acting repair and adjustment can be achieved, intestinal flora and systemic immunity are synergistically adjusted through targeted colon, and the pathological process of osteoarthritis is blocked from multiple ways. Clinical verifications show that the curative effect of the traditional Chinese medicine composition is obviously superior to that of conventional preparations and first-line western medicines, the safety is better, and an innovative treatment choice which takes effect quickly, takes effect for a long time and treats both symptoms and root causes is provided for patients.
Owner:HENAN GUOZHEN PHARM CO LTD

A cosmetic composition, method of making and use thereof

The present application relates to the field of medical or cosmetic formulations, the field of biopharmaceutical manufacturing technology and the field of preparation manufacturing technology, and in particular to a cosmetic composition, a preparation method and application thereof.The cosmetic composition comprises an active ingredient; the active ingredient comprises a chloranthus specious extract and a rhizoma corydalis extract; and the weight ratio of the chloranthus specious extract and the rhizoma corydalis extract is 0.6:1-1:1.The chloranthus specious extract and the rhizoma corydalis extract in the cosmetic composition provided by the present application are synergistic with each other, and have excellent soothing and repairing effects.
Owner:GUANGZHOU MASHANGHUI BIOTECHNOLOGY CO LTD

SSR molecular markers associated with the proliferation trait of Corydalis yanhusuo mother bulbs and their applications

PendingCN122303398ABiotechnologyGenotype
This invention provides SSR molecular markers associated with the proliferation trait of Corydalis rhizomes, belonging to the field of molecular genetics. Trait correlation analysis shows that Corydalis rhizomes proliferation is a key factor affecting its yield. This invention utilizes 24 pairs of SSR markers to perform regression analysis on the individual genotype and rhizome proliferation trait of Corydalis rhizomes. The association loci for Corydalis rhizomes proliferation were detected using the GLM program, explaining 18.73% of phenotypic variation, with the SSR molecular marker CYC2-8 showing a highly significant correlation. The primers provided by this invention for amplifying the aforementioned SSR molecular markers can be used to screen for superior Corydalis rhizomes with high rhizome proliferation, locate key genes controlling the rhizome proliferation trait, and for marker-assisted breeding, which is of great significance for cultivating high-yielding Corydalis rhizomes varieties.
Owner:INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI

Traditional chinese medicine formulation for preventing and treating constipation-predominant irritable bowel syndrome (IBS-c)

PendingUS20260021153A1Hydroxy compound active ingredientsDigestive systemPaeonia albifloraConstipation predominant irritable bowel syndrome
A composition of traditional Chinese medicine (TCM) comprising Corydalis Rhizoma, Paeoniae Radix, Magnoliae Officinalis Cortex, and Sennae Folium; a composition of extracts of the TCM composition; a pharmaceutical composition thereof; a method of using the same for treating constipation, including constipation-predominant symptoms (IBS-C); and a method of preparing the compositions. The various compositions disclosed herein are safe and effective in treating constipations.
Owner:CENT FOR CHINESE HERBAL MEDICINE DRUG DEV LTD

Benzyl isoquinoline alkaloid glycoside compound as well as preparation method and application thereof

The invention discloses a benzylisoquinoline alkaloid glycoside compound as well as a preparation method and application thereof. The preparation method comprises the following steps: soaking tubers of rhizoma corydalis in a 6% acetic acid solution, crushing, soaking in water, and carrying out ultrasonic extraction to obtain a plant extract; after water dispersion, carrying out HPD100 type macroporous resin column chromatography separation, carrying out gradient elution by using ethanol aqueous solutions with different concentrations, and collecting a 50% ethanol elution part to obtain an elution part YH-D; carrying out MCI column chromatography separation, and carrying out gradient elution by using a 0-100% methanol-water solution to obtain four parts of eluents; the preparation method comprises the following steps: dissolving YH-D-2 in water, filtering, and carrying out medium-pressure ODS column chromatography separation, Sephadex LH-20 column chromatography separation, medium-pressure ODS column chromatography separation and semi-preparative C18 column HPLC (High Performance Liquid Chromatography) purification on the filtrate to obtain six new compounds 1-6. In-vitro experiments prove that the elution part YH-D-2 containing benzylisoquinoline alkaloid glycoside of the benzylisoquinoline alkaloid glycoside compounds 1-6 has NO generation inhibition activity, and has a good development prospect as an anti-inflammatory drug.
Owner:DONGZHIMEN HOSPITAL OF BEIJING UNIV OF CHINESE MEDICINE

Traditional Chinese medicine compound composition as well as preparation method and application thereof

The invention provides a traditional Chinese medicine compound which is prepared from the following raw material medicines: rhizoma smilacis glabrae, rhizoma dioscoreae septemlobae, semen coicis, rhizoma curcumae longae, herba taxilli, radix salviae miltiorrhizae, cortex phellodendri, rhizoma acori graminei, plantain herb, rhizoma atractylodis macrocephalae, wine-treated rhubarb, radix angelicae pubescentis, bran-fried rhizoma atractylodis and vinegar-treated rhizoma corydalis, and also provides application of the traditional Chinese medicine compound composition in medicines for treating gout and gouty nephropathy. In addition, the invention also provides a preparation method of the sustained-release granule of the compound composition, which comprises the following steps: firstly, preparing the raw medicinal materials into a traditional Chinese medicine fluid extract, then adding the filler into the traditional Chinese medicine fluid extract, stirring to form a soft material, passing the soft material through a swinging granulator, and drying to obtain a medicine-containing pill core; and putting the pill cores into a fluidized bed, laterally spraying the slow-release coating solution, drying, and sieving to prepare the slow-release granules. The prepared traditional Chinese medicine formula sustained-release granules can release 90% or above within 8-10 hours, have a good constant-speed sustained-release characteristic, can meet the clinical requirement of 1-2 times of administration every day, and have good clinical application prospects and market value.
Owner:WANGJING HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI

Application of Tibetan medicine pellet preparation for treating chronic bronchitis

PendingCN121714655AAntipyreticAnalgesicsBiotechnologyGentiana algida
The invention discloses a Tibetan medicine Banjiaojiaopian pellet preparation, which comprises raw materials and auxiliary materials, the raw materials comprise the following components: gentiana algida, agilawood, choerospondias axillaris, white sandalwood, myristica fragrans, tabasheer, alpine horseradish, costus root, fructus chebulae, fructus terminaliae billericae, emblic leafflower fruit, tinospora sinensis merr, corydalis impatiens, clove and liquorice, and the auxiliary materials comprise an adhesive and a filler microcrystalline cellulose; the technological parameters for preparing the pellet preparation by adopting centrifugal granulation are as follows: the liquid spraying speed is 50ml / min, the number of revolutions of a turntable is 30r / min, and the air inlet temperature is 75 DEG C. Compared with traditional pills, the pellet preparation provided by the invention has the advantages of high dissolution rate, obviously improved bioavailability, reliable drug effect, accurate taking dosage, stable quality, low cost, good treatment effect, fine production process, good reproducibility, good quality controllability, high industrial production efficiency and wide application range.
Owner:张玲

A traditional Chinese medicine composition for treating osteoarthritis and a preparation method and use thereof

This invention provides a traditional Chinese medicine composition for treating osteoarthritis, prepared from the following raw materials in the indicated weight ratios: Corydalis Rhizome 8-12 parts, Red Peony Root 7.2-10.8 parts, Achyranthes Root 7.2-10.8 parts, Clematis Root 7.2-10.8 parts, White Peony Root 7.2-10.8 parts, Chaenomeles Root 7.2-10.8 parts, and Liquidambar Root 7.2-10.8 parts. This invention also provides a method for preparing this traditional Chinese medicine composition and its uses. This traditional Chinese medicine composition prioritizes promoting blood circulation and removing blood stasis, while also relaxing muscles and tendons, and nourishing blood and soothing the liver, thus achieving the combined effects of "promoting blood circulation and removing blood stasis, relaxing muscles and tendons." The combination of warming and cooling properties, along with a combination of tonifying and purging effects, removes blood stasis, clears the meridians, and improves joint mobility, thereby relieving knee pain, swelling, and limited mobility. Modern pharmacological studies have shown that the drug of this invention has anti-inflammatory, analgesic, microcirculation-improving, and cartilage-repair-promoting effects, which are highly compatible with the treatment needs of knee osteoarthritis.
Owner:SICHUAN CENT FOR TRANSLATIONAL MEDICINE OF TRADITIONAL CHINESE MEDICINE +1

A pharmaceutical composition for treating cervical spondylosis, preparation and application thereof

The application discloses a kind of drug composition for treating cervical spondylosis and its preparation and application, belong to traditional Chinese medicine composition technical field, the drug composition includes the following component by weight fraction: 6-28 parts of cornus officinalis, 6-28 parts of antler, 6-20 parts of cassia twig, 6-30 parts of kudzu root, 10-40 parts of astragalus, 6-16 parts of peach kernel, 6-16 parts of safflower, 6-20 parts of purple salvia miltiorrhiza, 6-20 parts of wine dengue, 6-20 parts of chuanxiong, 6-20 parts of red peony root, 6-20 parts of turmeric, 6-20 parts of frankincense, 6-20 parts of myrrh, 6-20 parts of notopterygium, 6-20 parts of rinkhals, 6-20 parts of sea wind, 6-20 parts of giant knotweed, 6-20 parts of corydalis, 6-15 parts of licorice.The drug composition can be added pharmaceutically acceptable adjuvant, and be made into preparation.The drug composition and preparation can be used for preparing the drug for treating cervical spondylosis mainly with wind, cold and damp.
Owner:HUALONG SHENGAI TRADITIONAL CHINESE MEDICINE GRP CO LTD

Preparation method and application of traditional Chinese medicine dispersion liquid containing self-assembled nanoparticles

The invention provides a preparation method of a traditional Chinese medicine dispersion liquid containing self-assembled nanoparticles, which comprises the following steps: mixing fructus piperis longi, rhizoma corydalis, radix angelicae, ligusticum wallichii, ligusticum and indigo naturalis, crushing, sieving to obtain a traditional Chinese medicine crushed material, adding purified water, carrying out ultrasonic extraction and suction filtration to obtain a traditional Chinese medicine extracting solution, centrifuging, removing precipitate, filtering supernate by a filter membrane, and drying to obtain the traditional Chinese medicine dispersion liquid containing the self-assembled nanoparticles. And carrying out ultrafiltration centrifugation, sucking liquid in the tube, and carrying out high-speed centrifugation to obtain the traditional Chinese medicine dispersion liquid containing the self-assembled nanoparticles. The invention also provides application of the traditional Chinese medicine dispersion liquid. The prepared traditional Chinese medicine dispersion liquid containing the self-assembled nanoparticles can relieve rat migraine caused by nitroglycerin, can remarkably improve the mechanical pain threshold and the heat pain threshold of model rats and remarkably promote callback of inflammatory factors and migraine markers in brain tissues of chronic migraine rats, and is used for preparing drugs for improving migraine through nasal administration.
Owner:SHAANXI PROVINCIAL INSTITUTE OF TRADITIONAL CHINESE MEDICINE (SHAANXI PROVINCIAL TRADITIONAL CHINESE MEDICINE HOSPITAL SHAANXI PROVINCIAL INSTITUTE OF INTEGRATED TRADITIONAL CHINESE & WESTERN MEDICINE)

Traditional Chinese medicine composition for ovary maintenance and application thereof

The invention relates to a traditional Chinese medicine composition for ovary maintenance and application thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following components: eucommia ulmoides, fructus cnidii, witch hazel, radix sophorae flavescentis, saffron crocus, leonurus, eclipta alba, golden cypress, stiff silkworm, radix rehmanniae, radix scrophulariae, radix polygonati officinalis, semen cuscutae, salvia miltiorrhiza, radix puerariae powder, aloe, chrysanthemum and angelica sinensis. The traditional Chinese medicine composition is used for preparing the herbal medicine plant bag, various herbal medicines are used, and the traditional Chinese medicine composition can be used for maintaining ovary, treating female postpartum vaginal relaxation, repairing damaged elastic fibers, treating vaginal relaxation from inside to outside and diminishing inflammation, and has the characteristics of quick effect, good curative effect, convenience in use, nature, safety and no side effect.
Owner:GUANGXI GAOZAN HEALTH MANAGEMENT CO LTD

Intelligent mosquito bite itching relieving liquid based on rhizoma corydalis extract and preparation method thereof

The invention discloses an intelligent mosquito bite itching relieving liquid based on a rhizoma corydalis extract and a preparation method thereof, and belongs to the technical field of daily chemicals and medicines. The antipruritic liquid is composed of 5-15% of rhizoma corydalis two-phase extract nanoparticles, 10-20% of temperature-sensitive liposome, 2-5% of a pH-responsive transdermal enhancer, 1-3% of a humectant, 0.5-2% of a thickening agent, 0.1-0.5% of a preservative and purified water. The preparation method comprises the following steps: synchronously obtaining rhizoma corydalis water-soluble alkaloid and fat-soluble terpenoid enrichment through dynamic solvent gradient extraction; the beta-cyclodextrin modified chitosan is used as a carrier and is embedded by a micro-fluidic chip to form nano-particles; constructing an intelligent transdermal system consisting of a citric acid-chitosan compound and lipidosome with the phase transition temperature of 32-37 DEG C; and mixing and molding through a micro-channel reactor. According to the invention, the efficient delivery and intelligent release of active components are realized through biphase extraction, molecular imprinting embedding and intelligent transdermal synergistic technologies.
Owner:LANZHOU HOKURIKU BIOLOGICAL TECH CO LTD

Pine-soot ink moxibustion and preparation method and use method thereof

The invention discloses pine-soot ink moxibustion as well as a preparation method and a use method thereof, and relates to the technical field of traditional Chinese medicine moxibustion therapy. Comprising the following raw materials: pine-soot ink, tourmaline powder, radix aconiti preparata, semen strychni preparata, sanguisorba officinalis, rhizoma corydalis, pseudo-ginseng, angelica sinensis, safflower carthamus, ligusticum wallichii, radix saposhnikoviae, gastrodia elata, frankincense, earthworm, herba epimedii, dogwood, lucid ganoderma, astragalus membranaceus, gynostemma pentaphyllum, artificial musk, wintergreen oil, borneol and beautifying wax. According to the pine-soot ink moxibustion and the preparation method and the use method thereof, the pine-soot ink is used as a substrate, the tourmaline powder is compounded, and a raw material system of multiple traditional Chinese medicines is selected, so that the product not only has the hot compress and pharmacodynamic permeation functions of the traditional Chinese medicines, but also has the adsorption characteristic of the pine-soot ink and the physical effects of negative ion release and far infrared effect generation of tourmaline; multiple synergy of a drug therapy and a physical therapy is realized, so that better health-care effects of relaxing tendons and activating collaterals, dispelling cold and removing dampness and relieving bone and joint pain are achieved.
Owner:SHANGHAI FANGYI E-COMMERCE CO LTD

Combined traditional chinese medicine formulation for treating herpes zoster and preparation method therefor

PCT designated stageWO2026016105A1AntiviralsPlant ingredientsViola yedoensisScutellariae radix
A combined traditional Chinese medicine formulation for treating herpes zoster and a preparation method therefor. The formulation consists of the following ingredients: 5-10 g of Violae Herba, 1-4 g of Menthae herba, 2-6 g of Cortex pseudolaricis, 5-17 g of Sophorae flavescentis radix, 7-20 g of Cnidii fructus, 4-12 g of Kochiae fructus, 2-6 g of Dictamni cortex, 4-7 g of Phellodendri chinensis cortex, 6-8 g of Gleditsiae spina, 8-25 g of costust root, 5-8 g of Angelicae sinensis radix, 3-10 g of Dictamni cortex, 2-6 g of camphor, 30-40 g of Vaseline, 1-4 g of Aurantii fructus, 1-3 g of Toosendan fructus, 2-4 g of Corydalis rhizoma, 1-3 g of Gentianae radix et rhizoma, 2-4 g of Gardeniae fructus, 2-5 g of Scutellariae radix, and 2-6 g of Carthami flos. The traditional Chinese medicine has a prominent effect. The traditional Chinese medicine not only relieves patients' pain and itching but also prevents recurrence, and the efficacy is stable.
Owner:LIU STELLA