200 results about "Joint swelling" patented technology

The invention relates to a traditional Chinese medicine composition and a preparation thereof, and especially relates to a pharmaceutical composition with effects of dispelling wind, relieving pain, dispelling cold, removing dampness, warming meridians and collaterals, relaxing meridians, and invigorating blood circulation, a hot-compress preparation and a preparation method thereof. The pharmaceutical composition for dispelling wind, relieving pain, dispelling cold, and removing dampness is mainly characterized by comprising the following raw materials by weight: 10-20 parts by weight of notopterygium roots, 10-20 parts by weight of radix angelicae pubescentis, 10-20 parts by weight of rhizoma atractylodis, and 10-20 parts by weight of radices sileris. Through clinical treatment demonstration by a lot of cases, the pharmaceutical composition of the invention has significant effect, is nontoxic, and good in stability; and a new traditional Chinese medicine preparation is provided with treatment, rehabilitation and health care effect on rheumatic joint swelling and pain, limb crymodynia, muscle and bone pain caused by wind-cold invasion, swelling and pain caused by soft tissue damage, ankylosis, and the like.

The inventors sought to provide compositions and methods of prophylaxis to prevent these harmful immune responses in patients and to prevent the related undesirable symptoms biological tissue such as for example inflammation, cell injury, tissue injury, tissue degradation, tenderness, redness, joint stiffness, joint swelling, restricted mobility and reduced strength. The inventors found that prophylactic therapy of an animal comprising administering a pharmaceutical composition comprising a GAG-peptide complex, optionally together with a connective tissue derived polypeptide, prevented the onset of at least one undesirable symptom.

Medicated wine for treating rheumatism comprises the compositions: 15 g of angelica sinensis, 10 g of radix rehmanniae praeparata, 15 g of rhizoma ligustici wallichii, 15 g of taxillus sutchuenensis, 10 g of radix paeoniae alba, 10 g of rhizoma gastrodiae, 10 g of radix rehmanniae, 10 g of poria cocos, 10 g of radix gentianae macrophyllae, 10 g of radix aucklandiae, 10 g of radix astragali preparata, 10 g of polygala tenuifolia, 15 g of Chinese wolfberry, 15 g of charred white atractylodes rhizome, 15 g of radix dipsaci asperoidis, 15 g of eucommia ulmoides, 10 g of cassia twig, 15 g of homalomena occulta, 10 g of illicium difengpi, 20 g of safflower, 15 g of radix saposhnikoviae, 7.5 g of radix achyranthis bidentatae, 10 g of herba schizonepetae, 10 g of pericarpium citri reticulatae, 10 g of semen brassicae, 10 g of apricot kernel, 15 g of papaya, 10 g of notopterygium root, 15 g of cortex acanthopanacis, 15 g of rhizoma cibotii, 1000 g of rock sugar, and 1500 mL of pure grain Baijiu. Through long-term clinical trials, the medicated wine overcomes the shortages of traditional medicated wine, has the health-care effects of adjusting the balance of yin and yang, clearing heat and detoxifying, promoting blood circulation to remove blood stasis, inducing diuresis for replenishing blood, tonifying qi, nourishing yin, strengthening spleen and stomach, tonifying liver and kidney, and regulating menstruation and relieving pain, and especially has relatively good therapeutic effects on rheumatism palsy, low back aching pain, muscles and bones pain and joint swelling and pain.

The invention discloses a healthcare silk quilt which is composed of two silk flocculi and a medicine quilt core serving as an interlayer. A traditional Chinese medicine composition in the medicine quilt core is prepared from, by weight, 10-20 parts of silkworm excrement, 2-4 parts of Albizia bark, 2-4 parts of Chinese parsnip root and 1-2 parts of tuber fleeceflower stem, the Chinese medicinal herbs except for silkworm excrement are crushed and then uniformly mixed with the silkworm excrement, and a mixture is spread and scattered into the medicine quilt core or subpackaged into a plurality of medicine bags to be placed into the medicine quilt core. The traditional Chinese medicine composition further comprises 2-4 parts of mulberry leaf and 2-4 parts of chrysanthemum flower, can comprise 1-2 parts of Szechuan lovage rhizome and 1-2 parts of Chinese angelica root or can comprise1-2 parts of and 1-2 parts of large-leaved gentian. The traditional Chinese medicine composition in the medicine quilt core is uniformly spread and scattered by 80-150g per square meter. The healthcare silk quilt has healthcare functions of keeping warmth, dispelling wind to remove dampness, harmonizing stomach to dissolve turbidity, nourishing heart to tranquilize mind and hypnotizing, and has certain curative effect on rheumatic arthralgia, damp turbidity blockage, vomiting and diarrhea spasm, joint swelling and pain, heat pain, insomnia, arthritis, rheumatism and rheumatoid.

The invention provides a device for detecting joint swelling parameters of a patient, which includes a housing, a take-up wheel assembly, an angle sensor, an acquisition circuit module and a wireless communication module arranged in the housing, and the disease can be detected through simple operations. The difference in wheel shaft rotation angle corresponding to the affected joint, as a disease parameter representing the joint swelling of the patient, has a reliable reference significance, and is easy to use and operate, and can be used for self-service detection by the patient, so as to realize the remote diagnosis of rheumatoid disease. The technical goal of monitoring and remote condition nursing provides the basis for the technical realization of condition parameter information collection; meanwhile, the present invention also provides a detection method and a detection system using the above-mentioned patient's joint swelling parameter detection device for detection operation, which is convenient for patients to monitor the patient's joint swelling. At the same time, it is convenient for doctors to obtain the patient's condition parameter data information, so as to remotely care for the patient's condition or make diagnosis and treatment judgments.

The present invention relates to a composition for improving the health status of various joints in the human body. The composition includes at least one plant extract as fatty base with active role, at least one extract from plants with anti-microbial properties, at least one extract from plants with analgesic and/or anti-inflammatory properties, and at least one extract from plants with anti-rheumatic and regenerative properties, to which dimethylsulfoxide, allantoin and/or potassium alum may be added. The composition may be used to treat osteoarthritis, rheumatic joint disease, joint swelling, pain, hallux valgus, traumatic conditions of the joints including sprains, strains, post-surgical recovery, bone edema, and speed up the recovery of athletes post-injury.

The invention discloses a joint repairing composition based on sturgeon cartilage active components and a preparation method of the joint repairing composition. The joint repairing composition is prepared from the following components in parts by weight: 80 to 95 parts of sturgeon cartilage type-II collagen, 1 to 10 parts of sturgeon cartilage chondroitin sulfate, 5 to 15 parts of glucosamine and 0.1 to 1 part of calcium caseinate. The joint repairing composition has the beneficial effects that the prepared joint repairing composition based on the sturgeon cartilage active components has a relatively good joint repairing effect, can be used as medical food for patients suffering from joint swelling pain, osteoporosis and the like and also can be used as a daily health product for old people with weak joint functions.

The invention discloses a Chinese medicinal bagged soaking agent for treating joint numbness pain. The bagged soaking agent is prepared from the following raw materials in part by weight: 10 to 15 parts of sappan wood, 4 to 8 parts of frankincense, 4 to 8 parts of myrrh, 4 to 8 parts of safflower, 8 to 12 parts of variegated coralbean bark, 8 to 12 parts of garden balsam stem, and 8 to 12 parts of common clubmoss herb. A preparation method for the bagged soaking agent comprises the following steps of: crushing the safflower and the common clubmoss herb into medium powder for later use; soaking the sappan wood, the variegated coralbean bark and the garden balsam stem into water, decocting, extracting, and filtering to obtain an aqueous extract; soaking the frankincense and the myrrh into ethanol, refluxing, extracting, and filtering to obtain an ethanol extract; and reclaiming the ethanol from the ethanol extract, then combining the ethanol extract and the aqueous extract, concentrating to obtain thick paste, adding the thick paste into the medium powder, mixing uniformly, granulating, drying, and packaging into filter paper bags. The bagged soaking agent has the effects of relaxing tendons, dredging channels and relieving swelling and pain, is used for treating the symptoms such as rheumatism and joint swelling, pain and function limitation caused by blood stagnated limbs, is convenient to use, and has a good curative effect.

The invention relates to a traditional Chinese medicine composition having effects of tonifying kidney and dredging collaterals and a preparation method thereof. The traditional Chinese medicine composition comprises malaytea scurfpea fruit, medicinal cyathula root, Chinese taxillus herb, rhizoma drynariae, white paeony root, sichuan lovage rhizome, suberect spatholobus stem and Rhizoma Dioscoreae Nipponicae. Results of multiple human body and animal experiments show that the traditional Chinese medicine composition can effectively relieve gonitis symptoms such as joint pain, joint swelling and joint function limitation. Compared with the prior art, the traditional Chinese medicine composition has better effects.

The invention provides medicine for treating rheumatism and rheumatoid. The medicine is glycoprotein, mixture of polysaccharide and protein, polypeptide or protein. The medicine has the advantages that the joint pain of rat rheumatic arthritis can be relieved effectively, and the joint pain threshold is increased evidently; the joint swelling of the rat rheumatic arthritis can be evidently relieved; rat hypothalamus L-ENK and beta-END contents can be increased, the secretion of proinflammatory factors such as IL-1beta and IL-6 can be lowered, the synthesizing and secretion of serum immunoglobulin IgG can be inhibited, and the release of pain excitation factor SP can be inhibited; the medicine is safe, efficient, free of side effect, and capable of preventing the pantalgia, joint pain and muscle pain caused by the rheumatism and rheumatoid, the joint swelling and pain, joint pain, neck and shoulder pain and waist and back pain not caused by trauma, and the joint pain caused by gout.

The invention discloses a Chinese patent medicine for treating rheumatism and rheumatoid arthritis, comprising the following components: 50-100 g of cassia twig, 30-70 g of radix paeoniae rubra, 40-90 g of coix seed, 40-90 g of achyranthes root, 40-90 g of loranthus parasiticus and 10-20 g of radix glycyrrhizae. If the components of the invention are taken at the same time, the Chinese patent medicine has the following advantages: the medicine is quite mild and has properties of reinforcement and elimination in combination, and the medicine is the best effective prescription for complementingliver and kidney, strengthening bones and tendons, tonifying spleen, eliminating dampness, activating blood circulation, and relieving bruises and pains. The Chinese patent medicine is suitable for treating pains of limbs caused by rheumatism and rheumatoid arthritis, joint swelling or variant, strain, bruises, wind, cold, wet, heat and Bi-syndrome. The medicine of the invention has low price of the drugs, has no toxic side effects, and completely realizes the aims of the invention at low cost, good curative effect and non toxic side effects.

The invention discloses a livestock and poultry calcium supplementing feed additive which comprises oyster calcium carbonate, calcium gluconate, calcium lactate, zinc gluconate, VD3, folic acid, pantothenic acid, nicotinic acid, biotin, selenium yeast, cane sugar, acid agents, microelements, emulsifiers, co-emulsifiers, antioxidants, preservatives and carriers. The invention further provides a formula of the livestock and poultry calcium supplementing feed additive and a manufacturing method. The additive can prevent whole body osteoporosis, bone mineral density reduction, incapability of standing, lameness, joint swelling deformation and paralysis caused by calcium deficiency of chicken, ducks, gooses and pigeons, egg weight and egg shell hardness can be obviously increased, egg shell and egg yolk colors are improved, and laying of eggs shell cracks, soft eggs, white skin eggs and sand cover eggs of cage rearing chicken and 'egg laying fatigue syndrome' are effectively prevented. Adolescent egg layers use the feed additive, so that shin bones and hip bones are well developed, and the body weight reaches standards. The additive is used for skeletal development of meat birds, so that skeletons are wide, and the body weight of the meat birds is increased. Besides, vitamins, selenium, microelements and the like can be supplemented, and the additive is sour and sweet in flavor and good in taste.

The invention provides an external traumatic medicine composition, which is prepared from the following raw materials in parts by weight: 30-70 parts of flowers carthami, 50-80 parts of radix achyranthis bidentatae, 5-13 parts of radix aconiti sinensis, 40-50 parts of ardisia hanceana, 10-18 parts of semen brassicae, 5-10 parts of fructus gardenia, 10-60 parts of rhizoma corydalis, 15-40 parts of peach kernel, 20-35 parts of rhizoma arisaematis, 15-25 parts of loofah sponge, 5-15 parts of radix dipsaci and 5-15 parts of polygonum cuspidatum. The invention also provides external traumatic medicinal oil and a preparation method thereof. The external traumatic medicine composition has the following beneficial effects that the external traumatic medicine composition is economical in materials, has a significant curative effect on kinds of traumatic injuries, has the functions of diminishing swelling, removing stasis, relaxing tendons, activating collaterals and relieving pain, can be used for treating soft tissue injuries such as skin swelling, congestion and joint swelling and pain caused by traumatic injuries and impact sprain, and is applicable to use under the condition of skin abrasion.

The invention provides an application of bovine bone collagen peptide in preparation of children's drinks to enhance bone development, and relates to the new medical application field of bovine bone collagen peptide. In the application of bovine bone collagen peptide in preparation of children's health care products or drinks to enhance bone development in the invention, the bone collagen in bovine bone collagen peptide may effectively prevent and improve osteoporosis; eliminate joint pain, keep off and reduce joint swelling, deformation and stiffness; accelerate fracture healing, and improvebone toughness; and keep off calcium loss and increase calcium absorption rate.

The invention relates to the field of natural medicaments, in particular to application of a philippine violet herb total phenol extract to treatment of hyperuricacidemia. Pharmacological tests prove that joint swelling of gouty arthritis of rats due to sodium urate crystals can be relieved obviously and the tread treatment of the rats can be improved by intragastric administration of the philippine violet herb total phenol extract. The philippine violet herb total phenol extract has the obvious inhibitory effect on hyperuricemia and urate nephropathy of mice due to a uricase inhibitor, adenine and ethambutol, but does not exert obvious influence on urinary volume, so the philippine violet herb total phenol extract has the effect of promoting the excretion of uric acid and has no effect of diuresis; and due to the single function of the philippine violet herb total phenol extract, doctors do not need to consider the influence of diuretic factors on patients during clinical application.

The invention discloses a drug for treatment of rheumatic arthritis. The drug is characterized in that it is a granule, a tablet or a capsule made from the following raw material drugs by weight: 2-4 of masson pine bark, 1.5-2.5 of field thistle, 2.3-3.5 of white paeony roots, 2-4 of roots of sageretia theezans, 1.5-2.5 of honeysuckle, 2-4 of panax notoginseng, 1.5-2.5 of sodium bicarbonate, 2-4 of Rhizoma Heterosmilacis Japonicae, 1.5-2.5 of radix rehmanniae, and 1.5-2.5 of eleusine indica. The drug provided in the invention is used for treating rheumatic arthritis, and after taking it, a good curative effect can be achieved. The drug has the efficacy of joint swelling reducing, pain relieving, and joint function recovery and improvement, etc. Through preliminary clinical verification, the drug has a rheumatic arthritis cure rate up to 96.5% and an effective rate of 100%. In addition, the drug also has the characteristics of easily available medicinal raw materials, and convenient administration, etc.

The invention discloses a black guinea-pig medicinal liquor and a preparation method thereof. The black guinea-pig medicinal liquor comprises the following components: a processed black guinea-pig, 1000-2000 g of grain liquor, 5-40 g of codonopsis pilosula, 5-40 g of Chinese Angelica, 5-40 g of astragalus membranaceus, 5-40 g of fructus lycii and 5-40 g of red dates. The black guinea-pig medicinal liquor disclosed by the invention is prepared by soaking the processed black guinea-pig and the corresponding traditional Chinese medicines with the grain liquor, and through reasonable compounding, all the medicines can have a good synergistic effect in the curative efficacy, and the efficacies of tonifying the liver and kidney, replenishing qi and blood, and relaxing and activating the tendons are jointly achieved. The black guinea-pig medicinal liquor can be used for adjuvant therapy of high blood pressure, hyperlipaemia, diabetes and the like, besides, the black guinea-pig medicinal liquor also has certain efficacies for treating hyperostosis, joint swelling and pain, lumbar disc herniation, gout and the like.

The present invention relates to a method for eliciting a disease modifying effect on an arthritic condition in a hip or stifle of a canine which comprises administering to the canine a therapeutically effective amount of a bisphosphonate. The present invention also relates to method for eliciting a disease modifying effect on hip dysplasia or stifle instability, the pain associated with hip dysplasia or stifle instability, joint swelling, shallowing of the acetabulum, narrowing of the joint space, subchondral bone sclerosis, preventing osteophyte formation and preventing joint destruction in a canine which comprises administering to the canine a therapeutically effective amount of a bisphosphonate.

The invention provides a plaster for assisting in treating rheumatic arthralgia. The plaster is characterized by comprising 5-15 percent of heracleum lanatum, 5-20 percent of prepared root of Chinese aconite, 10-35 percent of safflower, 5-20 percent of wooly datchmanspipe herb, 5-25 percent of eupolyphaga sinensis, 5-15 percent of pepper, 0.001-0.005 percent of artificial musk and 15-25 percent of garden balsam stem in a formula. A preparation method of the plaster comprises the steps of removing impurities, cleaning, drying, grinding, sieving and decocting to form the plaster. The plaster has various efficacies of promoting blood circulation and stopping pain, expelling wind and removing dampness, promoting blood circulation and removing blood stasis, clearing heat and detoxicating and the like and has unique curative effects of improving joint swelling, muscle and bone pain, sciatica and other bony lesions. In addition, by using the plaster, the activation of unit nerve cell tissues can be strengthened and the immunocompetence of human body can be improved.

The invention belongs to the technical field of pharmacy, and in particular relates to novel application of (2E,6E)-2-(3,5-dimethoxy phenylidene)-6-(4-chlorphenyl methylene)cyclohexanone and a derivative thereof. With a moderate/high dose, the (2E,6E)-2-(3,5-dimethoxy phenylidene)-6-(4-chlorphenyl methylene)cyclohexanone and the derivative thereof provided by the invention can remarkably reduce the acute gouty arthritis mouse ankle joint swelling degree and the serum uric acid level, meanwhile have very good NLRP3 and TLR4 dual inhibition activity, have effects better than that of a positive control dexamethasone, can be used for preparing medicines for treating hyperuricemia or acute gouty arthritis, and is small in side effect and high in safety.

Combination preparation, preparation method and combination packaging of Jingulian tablets with traditional Chinese medicine decoction pieces The present invention discloses a combination preparation, preparation method and combination packaging of Jingulian tablets with traditional Chinese medicine decoction pieces. Each component of part: 343 parts of Touguxiang, 400 parts of Chinese peach leaves, 370 parts of Daxueteng, 50 parts of Star Anise Maple, 50 parts of Jin Tie Suo, the combination preparation of Jingulian sheet Chinese medicine decoction pieces of the present invention dispels wind and dampness, reduces swelling and relieves pain , used for joint swelling and pain caused by rheumatic numbness, poor flexion and extension, etc., has good curative effect, quick effect, and no toxic side effects.

The invention relates to gel for resisting rheumatism and a preparation method thereof. The preparation method of the gel for resisting the rheumatism comprises the following steps: mixing 0.5 to 3 parts of wild grape root, 0.3 to 2 parts of Japanese cayratia herb, 0.5 to 2 parts of herba eupatorii chinansis, 0.5 to 2 parts of borneol cinnamomum camphora leaves and 0.5 to 2 parts of camphortree leaves; adding a pharmaceutically acceptable solvent, extracting, filtrating and collecting filtrate; adding carbomer into the filtrate to form gel filtrate; adding wintergreen oil, eucalyptus oil and capsaicin into the gel filtrate for emulsifying, thus obtaining the gel for resisting the rheumatism. The gel for resisting the rheumatism has a relatively good penetration effect, so that the gel canwell penetrate into the skin, and the symptoms of joint swelling and pain are quickly relieved.

The invention discloses a rheumatism pain-relieving plaster patch which is prepared from the following raw materials: rough materials are zaocys dhumnade, ephedra, saponin, radix aconiti, kusnezoff monkshood root, red paeony root; the seed of Job's tears, clematis root, angelica sinensis, ligusticum wallichii, rhizoma atractylodis, herba siegesbeckiae, radix angelicae pubescentis, pittosporum tobira, yam rhizome, akebiaquinata, peach kernel, centipede and Scorpio; and the fine material is prepared frankincense. The rheumatism pain-relieving plaster patch provided by the invention has the effects of warming yang and dispersing cold, benefiting qi and activating blood as well as relieving swelling and pain, and is used for treating arthrocele, non-agile motion, pain relieving with heat and pain increasing with cold, insensitiveness and pain immigration which are caused by the blocking of cold and dampness, has certain treatment efficacy for diseases of each kind of rheumatoid arthritis, rheumatic arthritis, cervical spondylosis, slipped discs, hyperostosis, scapulohumeral periarthritis, ankylosing spondylitis and the like, is convenient and rapid to use, has good treatment efficacy, is not administrated orally, has no side effects, and is low in treatment expense.

The invention discloses a formula of a hyperosteogeny treatment emplastrum. The formula comprises 3-5g of pangolin, 3-5g of ground beetle, 6-10g of Ligusticum wallichii, 6-10g of Aconitum kusnezoffii, 6-10g of Boswellia carteri, 6-10g of myrrh, 10-15g of Viciaamoena Fisch, 10-15g of Rhizoma Cibotii, 10-15g of Eucommia ulmoides, 10-15g of Chinese Taxillus Twig, 10-15g of Malaytea Scurfpea Fruit, 10-15g of Fructus Aurantii, 10-15g of Achyranthes bidentata, 10-15g of Salvia miltiorrhiza and 10-15g of Millettia dielsiana. The above components are respectively ground to fine particles with the size of 200-300 meshes, and the fine particles are mixed and blended in proportion to obtain the emplastrum for the external application of an afflicted part. The hyperosteogeny treatment emplastrum has the advantages of very fast treatment effectiveness, lasting and non-bounce effect, fundamental removal of the hyperosteogeny after long-term lasting use, no toxic side effects, avoiding of the damages of the oral administration of traditional Chinese medicines the liver and the kidney because of direct action on acupuncture points, and protruding effect especially on joint swelling, aches and limited activity caused by the hyperosteogeny.

The invention relates to an externally-applied traditional Chinese medicine composition for treating acute gouty arthritis and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following raw medicines in parts by weight: 5-6 parts of hairy holly root, 5-6 parts of giant knotweed, 1-2 parts of angelica, 1-2 parts of piper wallichii and 1-2 parts of borneol. The preparation method of the traditional Chinese medicine composition comprises the following steps of: respectively processing the raw medicines into powder; taking the fine powder of each raw medicine; mixing; sterilizing; bagging; and adding 8-15g of gooey to prepare the externally-applied traditional Chinese medicine composition. The traditional Chinese medicine composition is suitable for treating acute gouty arthritis, can be used for eliminating the symptoms of swelling and pain of joints of patients with acute gouty arthritis, has obvious effects on eliminating swelling and relieving pain after being externally applied on joints, has synergistic effects of the raw medicines, is fragrant, has the functions of clearing away heat, promoting diuresis, promoting blood circulation, removing heat from blood, eliminating toxicity and expelling stasis, and has the advantages of obvious treatment effect, short treatment period, low treatment cost and the like.

The invention provides application of indole-propioponic acid to preparing medicine for controlling rheumatoid arthritis, and relates to the technical field of rheumatoid arthritis disease treatment.Through the indole-propioponic acid, occurrence and development of experimental arthritis can be remarkably inhibited, and joint swelling symptoms are effectively relieved. The indole-propioponic acidcan inhibit a proinflammatory cell Th1 and a follicular helper T cell (Tfh) and increase the proportion of an anti-inflammation T regulatory cell (T regulatory, Treg). The indole-propioponic acid canalso reduce expression of proinflammatory factors IL-1beta, IL-6 and IL-17A in serum and anti-CII (anti-type II collage antibody), and can increase secretion of beta-endorphin with the analgesic effect. The indole-propioponic acid has anti-inflammation and immunosuppression effects, the unbalance state of immune cells in organisms can be corrected, and the aim of controlling rheumatoid arthritisis thus achieved.

The invention belongs to the technical field of nourishment, and particularly relates to a nutritional composition beneficial for joint comfortableness as well as a preparation method and applicationthereof. The nutritional composition beneficial for the joint comfortableness is prepared from collagen powder, anti-inflammation material, a detumescence material and an emulsifier, wherein the anti-inflammation material is prepared from one or several of fish oil, olive oil, rhizoma curcumae longae and piperine; the swelling subsiding material is prepared from bromelain and/or papain. The nutritional composition disclosed by the invention is capable of relieving joint discomfort through nutritional intervention, balancing nutrition and achieving the effects of repairing cartilago articularis, removing inflammatory response, removing arthrocele, strengthening ligamenta and building muscles.