22 results about "Monkshood Root" patented technology

The invention discloses medical soap for sterilizing, relieving itching and removing acne and a manufacturing method thereof, belonging to the field of articles of everyday use. The medical soap is prepared from ingredient A, ingredient B and ingredient C, wherein the ingredient A is prepared from dandelions, folium isatidis, rabdosia rubescens and glabrous sarcandra herb; the ingredient B is prepared from radix angelicae, rhizoma typhonii, white poria, Chinese angelia root tai, radix pseudostellariae, raw milkvetch root, Chinese honeylocust fruit, red paeony root, prepared kusnezoff monkshood root, radices lithospermi, cortex dictamni, thunberg fritillary bulb, fiveleaf akebia fruit, white muscardine silkworms and solanum lyratum; the ingredient C is prepared from soap base, honey and bovine bone marrow oil. The medical soap disclosed by the invention is used for external washing or smearing after being wet by adding water in the morning and evening every day; after a person with smelly feet washes the feet, the medical soap is smeared in gaps between toes; and the medical soap is not suitable for use when the skin is damaged. The medical soap prepared by the invention is a black brown solid body, and has soap medicine odor; the medical soap can be used for nourishing the skin, is antiallergic, beautifies the features, removes acne, relieves itching, removes freckles, clearing heat and deterring sweat; the medical soap can beautify the features, whiten the skin, and remove the acne and the freckles when used for washing the face, and can deter the sweat, remove the smelly odor and treat dermatophytosis when used for washing the feet; and the medical soap has a control effect on the itching toxin which appears after mosquito bite, and has a moisturizing effect for the person having the dry skin.

The invention provides an external traditional Chinese medicine composition for treating knee osteoarthritis and a preparation method thereof. The traditional Chinese medicine composition is prepared from Chinese angelica, safflower, pollen typhae, herba schizonepetae, zedoary, radix clematidis, notopterygium root, cortex periplocae, cortex erythrinae, caulis spatholobi, fried szechwan chinaberry fruit, rhizoma smilacis glabrae, salvia miltiorrhiza, pepper, garden balsam stem and prepared kusnezoff monkshood root. The external traditional Chinese medicine composition for treating knee osteoarthritis is reasonable in compatibility of the components, dredges channels and collaterals, activates blood circulation to remove blood stasis, enables qi and blood of tendons and vessels to be smooth, eliminates dampness and coldness, and relieves pain, so that the treatment purpose is achieved.

The invention provides a traditional Chinese medicine gel emplastrum for treating gouty arthritis and a preparation method thereof, the traditional Chinese medicine gel emplastrum for treating gouty arthritis at least comprises a gel layer loaded with a traditional Chinese medicine extract, the traditional Chinese medicine extract comprises the following raw materials: semen coicis, cortex phellodendri, radix clematidis, kadsura coccinea, rhizoma atractylodis, rhizoma dioscoreae hypoglaucae, red psychotria leaf, alangium platanifolium, kadsura pepper stem, radix aconiti, radix aconiti agrestis, semen strychni, frankincense, myrrh, angelica sinensis, safflower carthamus, radix cyathulae, radix paeoniae rubra, rhizoma smilacis glabrae, lycopodium clavatum, radices hemerocallis, weeping willow twig, evodia lepta, swamp mahogany, radix sophorae flavescentis, herba andrographitis, Chinese lobelia, coptis chinensis, edible tulip, cassia twig, pepper and borneol; a matrix of the gel layer is prepared from the following raw materials in parts by weight: silk fibroin, polyvinyl pyrrolidone, azide-polyethylene glycol-carboxylic acid, 1-ethynyl cyclopropyl carboxylic acid, 2, 5-dicarboxylic acid-3, 4-ethylenedioxythiophene and glycerol. The traditional Chinese medicine gel emplastrum disclosed by the invention can achieve a good treatment effect through percutaneous absorption.

The invention discloses a traditional Chinese medicine composition for treating rheumatic bone pain and a preparation method of the traditional Chinese medicine composition, and relates to the technical field of traditional Chinese medicines. The ointment consists of traditional Chinese medicine components and auxiliary materials, wherein the traditional Chinese medicine components of the ointment are prepared from the following components: unprocessed radix aconiti, unprocessed radix aconiti kusnezoffii, scorpio, centipede, earthworm, frankincense, myrrh, notopterygium root, radix angelicae pubescentis, radix clematidis, gentiana macrophylla, lycopodium clavatum, safflower and phryma leptostachya; the decoction is prepared from the following components: eucommia ulmoides, longspur epimedium, radix rehmanniae preparata, raw astragalus membranaceus, teasel root, semen cuscutae, radix achyranthis bidentatae, radix clematidis, salvia miltiorrhiza, radix aconiti preparata, prepared kusnezoff monkshood root, angelica sinensis and liquorice. According to the invention, a treatment mode of combining external use of ointment and oral administration of decoction is innovatively adopted, aiming at the pathogenesis characteristics of rheumatism ostalgia, local symptoms are rapidly relieved through the external ointment, the internal organ function is fundamentally conditioned through the oral decoction, the treatment strategy of treating symptoms in emergency and treating root causes in slow is realized, and the clinical curative effect is remarkably improved.

The invention discloses a muscle and bone patch for treating lumbago. The traditional Chinese medicine is prepared from the following raw materials by weight: 5 to 7 grams of prepared kusnezoff monkshood root, 5 to 7 grams of radix aconiti, 5 to 7 grams of herba asari, 14 to 16 grams of cassia twig, 14 to 16 grams of cortex eucommiae, 14 to 16 grams of radix dipsaci, 14 to 16 grams of rhizoma drynariae, 14 to 16 grams of radix angelicae pubescentis, 14 to 16 grams of radix clematidis, 14 to 16 grams of radix achyranthis bidentatae, 9 to 11 grams of frankincense, 9 to 11 grams of myrrh, 9 to 11 grams of flos carthami, 17 to 19 grams of caulis spatholobi, 17 to 19 grams of herba lycopodii, 17 to 19 grams of herba speranskiae tuberculatae and 11 to 13 grams of herba lycopi. The ointment is prepared by the following steps: weighing and preparing the raw materials according to the proportion, crushing the medicines, sieving with a 120-mesh sieve to obtain fine powder, blending honey, egg white, wine for treating cold symptoms, vinegar and the fine powder into thick paste, and coating the thick paste on a dressing to prepare the ointment. The traditional Chinese medicine has the effects of warming channels and expelling cold, activating meridians to stop pain, tonifying kidney and strengthening waist, strengthening bones and benefiting spines, clearing damp and dispersing blood stasis, activating meridians to stop pain, penetrating channels and inducing meridians and relieving swelling and urgency, has a good treatment effect on lumbago, does not have side effects, and has a good popularization prospect and a good medical economic value.

The invention discloses a pharmaceutical composition for bone fracture and a preparation and a preparation method thereof. The pharmaceutical composition is prepared from, by weight, 2-6 parts of calcined native copper, 0.5-1.5 parts of himalayan teasel root pieces, 6-8 parts of dried ginger, 0.5-1.5 parts of ground beetles, 1.5-2.5 parts of prepared kusnezoff monkshood roots, 1.5-2.5 parts of large-leaved gentian, 30-40 parts of vinegar frankincense, 30-40 parts of vinegar myrrh, 0.5-1.5 parts of muskmelon seeds, 1.5-2.5 parts of pseudo-ginseng, 0.5-1.5 parts of prepared nux vomica, 0.5-1.5 parts of dragon's blood, 0.5-1.5 parts of safflower and 0.5-1.5 parts of radix stephaniae tetrandrae. , 0.5 to 1.5 parts of Chinese angelica, 1.5 to 2.5 parts of radix aconiti preparata, and 0.5 to 1.5 parts of cassia twig. And a transdermal absorption plaster preparation is prepared. The pharmaceutical composition and the preparation thereof have the functions and functions of mainly treating bone reunion and swelling and pain relief, and are used for various types of closed fractures. A plurality of traditional Chinese medicine components are reasonably proportioned, the preparation method is unique, the auxiliary materials are well proportioned, the forming effect is good, the patch can be directly pasted on the affected part, the main medicine is uniformly dispersed in the matrix through transdermal absorption, the medicine directly reaches the affected part, the medicine effect is directly exerted, the effect is strong, the curative effect is remarkable, the use is convenient, and the medication is safe.

The invention provides a preparation method of prepared kusnezoff monkshood root decoction pieces. The preparation method comprises the following steps: (1) dividing kusnezoff monkshood roots into large kusnezoff monkshood roots which are larger than or equal to a cm and small kusnezoff monkshood roots which are smaller than a cm according to the Dividing the kusnezoff monkshood root into a grade I of less than b, a grade II of more than or equal to b and less than or equal to c and a grade III of more than c according to the mass percentage content of the total amount of the monoester alkaloid; obtaining a small radix aconiti agrestis file I, a large radix aconiti agrestis file I, a small radix aconiti agrestis file II, a large radix aconiti agrestis file II, a small radix aconiti agrestis file III and a large radix aconiti agrestis file III; (2) respectively adding water into the small radix aconiti agrestis file I, the large radix aconiti agrestis file I, the small radix aconiti agrestis file II, the large radix aconiti agrestis file II, the small radix aconiti agrestis file III and the large radix aconiti agrestis file III for soaking; (3) boiling the soaked radix aconiti kusnezoffii; and (4) drying to obtain the prepared kusnezoff monkshood root Wherein in the step (1), a ranges from 1 to 1.5, b ranges from 0.015% to 0.025%, and c ranges from 0.035% to 0.045%. The radix aconiti kusnezoffii is graded according to the size and the content of the monoester alkaloids, so that the content of the monoester alkaloids in the prepared radix aconiti kusnezoffii decoction pieces is increased while the low toxicity of the radix aconiti kusnezoffii is

The invention provides traditional Chinese medicinal liquor with tendon dredging and blood activating effects and a brewing method of the traditional Chinese medicinal liquor. The medicinal liquor is prepared from the following raw materials in parts by weight: 2-5 parts of angelica sinensis, 1-3 parts of rhizoma drynariae, 2-5 parts of fructus liquidambaris, 2-5 parts of caulis spatholobi, 1-6 parts of radix angelicae pubescentis, 3-5 parts of grape root, 2-5 parts of radix angelicae, 5-8 parts of cassia twig, 1-6 parts of prepared tripterygium wilfordii, 4-10 parts of mint, 3-4 parts of pseudo-ginseng, 2-5 parts of prepared pinellia ternate, 3-6 parts of safflower, 2-7 parts of honeysuckle, 2-5 parts of prepared arisaema consanguineum schott, 2-5 parts of prepared kusnezoff monkshood root, 1-5 parts of prepared radix aconiti, 3-8 parts of eucommia ulmoides and 550-650 parts The tendon-dredging and blood-activating medicinal liquor has the beneficial effects that the tendon-dredging and blood-activating medicinal liquor with synergistic interaction and high safety is provided through specific medicinal material compatibility and a processing technology, and the effects of warming channels, expelling cold, dispelling wind and eliminating dampness are achieved.

The invention relates to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine ointment for rapid bone setting. The traditional Chinese medicine ointment is prepared from the following raw materials in parts by weight: 1 to 10 parts of semen strychni, 1 to 20 parts of herba lycopodii, 1 to 7 parts of catechu, 1 to 10 parts of myrrh, 1 to 5 parts of dragon's blood, 1 to 20 parts of garden balsam stem, 1 to 5 parts of radix aconiti agrestis, 1 to 8 parts of indigo naturalis, 1 to 5 parts of rhizoma kaempferiae, 1 to 10 parts of borneol, 1 to 8 parts of radix aconiti, 1 to 15 parts of frankincense, 1 to 25 parts of radix saposhnikoviae, 1 to 18 parts of radix dipsaci, 1 to 15 parts of rhizoma smilacis glabrae, 10 to 25 parts of rhizoma drynariae, 1 to 10 parts of musk and 2 to 5 parts of achyranthes aspera. The raw materials are processed and prepared into mixed medicine powder, sesame oil and minium are taken, the mass ratio of the sesame oil to the minium to the mixed medicine powder is 1: 1: 1, firstly, the sesame oil is put into a container to be heated, then the obtained mixed medicine powder is added, after uniform stirring, decoction is conducted for 30 seconds, flameout is conducted for natural cooling, then minium is put into the container, uniform stirring is conducted again, and the mixture in the container is oxidized to be dark. The ointment is suitable for traumatic injury and fracture swelling and pain, and can accelerate fracture healing and relieve local pain and swelling when being externally applied.

The invention belongs to the field of plasters, and particularly discloses an anti-inflammatory and analgesic plaster and a preparation method thereof. The traditional Chinese medicine composition comprises 20 to 30 g of monkshood, 20 to 30 g of kusnezoff monkshood root, 20 to 50 g of ground beetle, 20 to 30 g of paris polyphylla, 20 to 30 g of frankincense, 20 to 30 g of myrrh, 20 to 40 g of stir-baked squama manitis, 20 to 30 g of ligusticum wallichii, 20 to 30 g of turmeric, 20 to 30 g of radix rehmanniae, 20 to 30 g of grub, 10 to 20 g of pseudo-ginseng, 10 to 20 g of dragon's blood, 10 to 20 g of scorpion, 10 to 20 g of divaricate saposhnikovia root, 30 to 50 g of garter snake, 30 to 50 g of caulis spatholobi, 30 to 40 g of pawpaw, 25 to 40 g of safflower, 30 to 40 g of Chinese angelica, 30 to 40 g of radix 55-65 g of rhizoma corydalis, and 2.5-3.2 kg of oil; through the combined action of the radix salviae miltiorrhizae, the flos carthami and the rhizoma chuanxiong, blood circulation is promoted, pain caused by blood stasis is reduced, the radix angelicae pubescentis and the rhizoma chuanxiong can achieve the pain relieving effect through different ways, the compound pain relieving effect is formed, and the plaster has the good effects of promoting blood circulation to remove blood stasis, diminishing inflammation and relieving pain.

The invention relates to a treatment patch for vein tendons and muscles and a preparation method thereof, and relates to the technical field of meridian treatment, the treatment patch comprises pepper, peruvian groundcherry herb, South African leaf, betelnutpalm male flower, Chinese angelica, asarum, frankincense, dragon's blood, radix aconiti preparata, prepared kusnezoff monkshood root, rhizoma dioscoreae nipponicae, impatiens balsamina, lycopodium clavatum, radix clematidis, myrrh, borneol, pressure-sensitive adhesive, methyl ester, salicylic acid, beach morningglory herb, motherwort and ceramic powder. According to the treatment patch for veins and tendons and muscles and the preparation method thereof, pepper and peruvian groundcherry herb are used for warming middle-jiao and relieving pain for meridians and collaterals of a user, heat is provided for dispelling cold for the used meridians and collaterals, South African leaves are used for clearing away heat and toxic materials for the user, angelica sinensis and frankincense are used for regulating menstruation and relieving pain, and ulcers and sores and traumatic injuries are treated; therefore, heat is provided for meridians and collaterals of the whole body, and dampness and cold are eliminated. The raw materials such as pepper, peruvian groundcherry herb, South African leaf, betelnutpalm male flower, Chinese angelica, manchurian wildginger and frankincense are added into the treatment patch, so that the meridians of a user can be treated.

The invention discloses a preparation method of a Waixiao pain capsule. The preparation method comprises the following steps: (1) preparing raw medicinal powder as base powder; weighing Chinese angelica, pseudo-ginseng, dahurian angelica root and prepared kusnezoff monkshood root, crushing into coarse powder, sieving and mixing; (2) preparing mixed clear paste; step (3): mixing; adding the prepared clear paste into a spray trolley matched with a spray drying granulator, adding the raw medicinal powder prepared in the step (3) into the spray drying granulator, heating the raw medicinal powder to a set temperature, spraying the clear paste into the spray drying granulator through the spray trolley, and intermittently shaking bags to form a mixture; (4) crushing and sieving the mixture; (5) uniformly mixing the fine powder with paracetamol; and (6) filling the mixed medicine powder into capsules. The process steps of drying the clear paste and crushing the clear paste into dry powder are reduced, the operation process is remarkably simplified, the retention rate of effective components is higher, and the product quality and the production efficiency are improved.

The invention belongs to the technical field of Chinese patent medicine preparations, and particularly relates to a muscle and bone tablet with reduced toxic and side effects and a preparation method and application thereof. The muscle and bone tablets are prepared from the following traditional Chinese medicine raw materials: radix aconiti preparata, herba epimedii, cyrtomium fortunei, cornu cervi pantotrichum, asarum, flos carthami, lumbricus, scalded rhizoma drynariae, red ginseng, prepared kusnezoff monkshood root, radix achyranthis bidentatae, cortex phellodendri chinensis, radix dipsaci, ephedra, acanthopanax, parasitic loranthus, anisetree bark, prepared semen strychni, notopterygium root, zaocys dhumnade, dark plum, cassia twig, honeysuckle, liquorice and prepared myrrh. The muscle and bone tablet is an upgraded product prepared by improving the preparation method of the Wantong muscle and bone tablet. The muscle and bone tablets have a good detoxification effect on radix aconiti preparata and radix aconiti kusnezoffii preparata, meanwhile, the effects of expelling wind, removing cold and activating meridians to stop pain of the muscle and bone tablets can be improved, and the problems that in clinical application, due to the fact that a patient takes the Wantong muscle and bone tablets for a long time, the medicine side effect is high, and safety is low are effectively solved.

The invention relates to the technical field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for relieving lumbago, a traditional Chinese medicine preparation and a preparation method and application thereof. The traditional Chinese medicine composition contains rheum officinale, pinellia ternate, cape jasmine, coptis chinensis, goat bones, cucumber seeds, prepared kusnezoff monkshood roots, curcuma zedoary, ground beetles, artemisia rupestris, frankincense, myrrh and liquorice. The preparation method of the traditional Chinese medicine preparation for relieving lumbago comprises the following steps: mixing a mixture A of rheum officinale, pinellia ternate, cape jasmine, coptis chinensis, goat bones and cucumber seeds with a solvent containing monohydric alcohol, carrying out alcohol extraction for at least one time, and collecting an alcohol extract; and mixing the mixture B of prepared kusnezoff monkshood root, curcuma zedoary, ground beetle, artemisia rupestris, frankincense, myrrh and liquorice with water, decocting for at least one time, and performing solid-liquid separation to obtain the water extract. The invention also provides application of the traditional Chinese medicine composition prepared by the method or the traditional Chinese medicine preparation prepared by the method in medicines for relieving back pain. The traditional Chinese medicine composition has the effects of relieving pain, diminishing swelling, dredging collaterals and strengthening tendons and bones.

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating pain and a preparation method and application thereof. The traditional Chinese medicine composition is composed of eleven traditional Chinese medicines including polygonum cuspidatum, pseudo-ginseng, rheum officinale, cape jasmine, chrysanthemum, safflower, processed rhizoma arisaematis, processed radix aconiti, processed kusnezoff monkshood root, vinegar frankincense and vinegar myrrh, the compatibility is precise and appropriate, synergistic interaction is achieved, and the traditional Chinese medicine composition has the effects of promoting blood circulation to remove blood stasis and relieving swelling and pain. Especially musculoskeletal pain caused by osteoarthritis, fracture, soft tissue injury, cervical spondylosis, scapulohumeral periarthritis, protrusion of lumbar intervertebral disc and the like, the total response rate after treatment is 87.98%, and the patient satisfaction degree is larger than 90%.

The invention discloses a traditional Chinese medicine pellet for conditioning heart-kidney disharmony type insomnia and a preparation method of the traditional Chinese medicine pellet. The traditional Chinese medicine pellet is prepared from coptis chinensis, cinnamon, spina date seed, platycladi seed, polygala tenuifolia, radix ophiopogonis, schisandra chinensis, angelica sinensis, prepared rehmannia root, radix paeoniae alba, poria cocos, rhizoma alismatis, dogwood, moutan bark, tuber fleeceflower stem, cortex albiziae, rhizoma acori graminei, fructus alpiniae oxyphyllae, mulberry, glossy privet fruit and auxiliary materials. The specific preparation method comprises the following steps: pretreating the medicinal materials, crushing, mixing, preparing a soft material, pelleting, drying, coating, granulating and packaging. The traditional Chinese medicine pellet has the beneficial effects that the traditional Chinese medicine pellet has a better conditioning effect; the traditional Chinese medicine pellet has better convenience; the traditional Chinese medicine pellet has relatively high compliance; the traditional Chinese medicine pellets are convenient to absorb; the medicine effect of the traditional Chinese medicine pellet is accurate and lasting; the preparation method effectively improves the stability of the traditional Chinese medicine pellet.

The invention relates to a thin-layer identification method and application of kusnezoff monkshood root and / or prepared kusnezoff monkshood root formula granules, and the identification method comprises the following steps: (1) mixing a kusnezoff monkshood root reference medicinal material with water, and carrying out reflux extraction to obtain a reference medicinal material solution; (2) mixing a to-be-detected sample with methanol, and performing ultrasonic treatment to obtain a test solution; and (3) carrying out thin-layer chromatography analysis on the reference medicinal material solution and the test solution. According to the thin-layer identification method provided by the invention, a reference medicinal material identification method is creatively added for identifying the prepared kusnezoff monkshood root formula granules, so that the specificity of the method is greatly improved, the information amount is large, and the kusnezoff monkshood root and the prepared kusnezoff monkshood root formula granules can be identified more accurately; and the used solvent is non-toxic, does not pollute the environment, does not cause harm to the body health of operators, and is easy to popularize and use.

The invention relates to the technical field of traditional Chinese medicinal liquor, in particular to external medicinal liquor for gout and a preparation process thereof, the external medicinal liquor for gout comprises the following raw materials: centipede, sapium sebiferum, cassia twig, radix aconiti preparata, prepared kusnezoff monkshood root, angelica sinensis, mulberry twig, polygonum cuspidatum, lycopodium clavatum, garden balsam stem, radix angelicae pubescentis, gentiana macrophylla, angelica dahurica, safflower, notopterygium root, divaricate saposhnikovia root, asarum, ash bark, Chinese starjasmine stem and white spirit. The medicinal liquor has the beneficial effects that the medicinal liquor is obtained by soaking the centipede, the sapium sebiferum, the cassia twig, the radix aconiti preparata, the prepared kusnezoff monkshood root, the angelica sinensis, the mulberry twig, the polygonum cuspidatum, the lycopodium clavatum, the garden balsam stem, the radix angelicae pubescentis, the gentiana macrophylla, the radix angelicae, the safflower, the notopterygium root, the divaricate saposhnikovia root, the asarum, the cortex fraxini and the Chinese starjasmine stem in the white spirit, and the medicinal liquor has the effects of promoting blood circulation to remove blood stasis, dispelling wind and eliminating dampness and activating meridians to stop pain by being smeared on the gout affected part; arthralgia of gout patients can be effectively relieved; the external medicinal liquor for gout is simple and convenient to prepare, easy to operate and suitable for industrial production.

The invention provides a specific chromatogram construction method and application of a prepared kusnezoff monkshood root aqueous extract and formula granules, and the specific chromatogram construction method of the prepared kusnezoff monkshood root comprises the following steps: obtaining a specific chromatogram of an object to be detected by adopting a high performance liquid chromatography; specific chromatographic conditions of the high performance liquid chromatography are provided, and octadecylsilane chemically bonded silica is used as a chromatographic column of a filler; acetonitrile is used as a mobile phase A, an aqueous solution containing 0.18%-0.22% of triethylamine and 0.18%-0.22% of glacial acetic acid is used as a mobile phase B, and elution is performed according to a specific gradient program; the detection wavelength is 238 to 242 nm in 0 to 14 minutes, the detection wavelength is 278 to 282 nm in 14 to 38.5 minutes, and the detection wavelength is 238 to 242 nm in 38.5 to 59 minutes. The material information in the characteristic chromatogram obtained by the construction method is comprehensive, and the overall quality control of the prepared kusnezoff monkshood root and the identification of easily mixed products of the prepared kusnezoff monkshood root can be realized through the related information in the characteristic chromatogram represented by the method.

The invention provides application of radix aconiti kusnezoffii extract and relates to the technical field of bacteriostasis, the application of the radix aconiti kusnezoffii extract is used for inhibiting growth of escherichia coli, and the minimum inhibitory concentration of the radix aconiti kusnezoffii extract is 2.5 mg / mL; the kusnezoff monkshood root extract can directly destroy cell walls and cell membranes of bacteria, down-regulate key genes of a flagellum assembly pathway, interfere a core metabolic pathway of the bacteria, and down-regulate a two-component system, ABC transporter and other related genes; the MIC of the radix aconiti agrestis extract to escherichia coli is determined to be 2.5 mg / mL clearly for the first time, an accurate dosage basis is provided for development of the radix aconiti agrestis extract into an antibacterial preparation, and it is proved that the radix aconiti agrestis extract has a clear and quantifiable direct antibacterial effect; meanwhile, through a multi-target attack strategy of membrane rupture, leg breaking, grain breaking and blinding, bacteria are difficult to generate drug resistance through single mutation, and a new thought is provided for solving the problem of drug resistance of antibiotics.

The invention discloses a traditional Chinese medicine external spray for treating shoulder, neck, waist and leg pain and a preparation method thereof. The traditional Chinese medicine external spray is characterized by comprising the following components in parts by weight: 6-10 parts of radix aconiti preparata, 6-10 parts of prepared kusnezoff monkshood root, 10-15 parts of safflower, 10-12 parts of ligusticum wallichii, 10-15 parts of beefwood-like clubmoss herb, 5-8 parts of scorpion, 3-5 parts of asarum, 10-12 parts of salvia miltiorrhiza, 8-10 parts of yellow ginger and 2-4 parts of borneol. According to the external traditional Chinese medicine spray for treating shoulder, neck, waist and leg pain and the preparation method of the external traditional Chinese medicine spray, the effects of promoting blood circulation to remove blood stasis, dispelling wind and eliminating dampness and activating meridians to stop pain can be achieved on local swelling and pain caused by shoulder, neck, waist and leg pain such as cervical spondylosis, lumbar disc herniation, lumbar muscle degeneration, rheumatic arthritis, rheumatoid arthritis and traumatic injuries.