This invention belongs to the field of
traditional Chinese medicine (TCM) technology, specifically relating to a TCM composition with detoxifying and
uterus-warming effects and its application in the preparation of external products. The medicinal component of this external TCM product is composed of fenugreek, amethyst, rose,
pomegranate seed,
centella asiatica,
long pepper, five-finger peach,
lycopodium, litchi seed, and
achyranthes bidentata. Animal experiments show that this product can significantly reduce the number of writhing movements in animals with cold-induced
blood stasis type dysmenorrhea, lower COX-2 and PGE2 levels in the
uterus, and improve peritoneal
inflammation, demonstrating good detoxifying,
blood stasis-removing, menstruation-regulating, and pain-relieving effects. Regarding blood
rheology, it exhibits the effects of inhibiting
platelet aggregation, dilating blood vessels, reducing
blood viscosity, and balancing TXA2 and PGI2 levels, reflecting its effects of warming the kidneys and
uterus, and strengthening the body's foundation. In summary, the TCM composition of this invention and its prepared external product can warm the kidneys and uterus, promote
diuresis and eliminate
turbidity, providing a novel TCM
external application solution for the
clinical treatment of cold-induced
blood stasis type dysmenorrhea.