11 results about "Chronic renal failure" patented technology

To provide a jelly composition containing spherical adsorptive carbon for improving uremic symptoms and delaying initiation of dialysis of chronic renal failure patients, which has more improved medication compliance than existing therapeutic agents.SOLUTION: The jelly composition contains spherical adsorptive carbon as an active ingredient, a gelling agent, a thickener, and spherical adsorptive carbon containing distilled water.SELECTED DRAWING: Figure 2

This invention belongs to the field of pharmaceutical analysis, specifically relating to a method for constructing a fingerprint spectrum of Shenfushu granules. The method for constructing a fingerprint spectrum of Shenfushu granules provided by this invention features high accuracy, high stability, good repeatability, good specificity, and strong specificity. The fingerprint spectrum analysis method for Shenfushu granules, a traditional Chinese medicine preparation for treating chronic renal failure, established by this invention can not only qualitatively analyze and identify the seven chemical components contained in this preparation, but also simultaneously present the characteristic peaks of five traditional Chinese medicines in the prescription, achieving the goal of overall quality control of multiple medicinal ingredients.

The invention belongs to the field of traditional Chinese medicines, and provides a medicine for treating or adjunctively treating chronic renal failure, which is prepared from the following raw material medicines in parts by weight: 5-15 parts of ginseng; 5-20 parts by weight of bighead atractylodes rhizome; 10-30 parts by weight of wrinkled gianthyssop herb; 10-30 parts by weight of amomum tsao-ko; 5-20 parts by weight of Chinese angelica; 5-25 parts by weight of ligusticum wallichii; 5-20 parts by weight of rheum officinale; 5-20 parts by weight of curcuma zedoary; 5-20 parts by weight of rhizoma sparganii; and 10-30 parts by weight of Radix Astragali. The components in the medicine provided by the invention are reasonable in compatibility and synergistic in effect, can relieve progressive deterioration of renal function and improve biochemical indexes of patients, has an obvious treatment effect on chronic renal failure, does not have obvious toxic or side effects, and is very suitable for popularization and application.

The invention belongs to the technical field of biological medicines, and particularly discloses a liposome containing a natural extract composition as well as a preparation method and application of the liposome. The method for preparing the liposome containing the natural extract composition comprises the following steps: S1, adding the grape, poria cocos and apple extract, cholesterol and lecithin into an organic solvent, heating, stirring and dissolving to obtain an organic phase; adding the soybean extract and the ginseng extract into ultrapure water, heating and stirring to obtain a water phase; and S2, slowly adding the organic phase into the water phase while stirring, continuing stirring and emulsifying, and removing the organic solvent by reduced pressure distillation to obtain a liposome suspension. And S3, filtering the suspension, adding a freeze-drying protective additive, and freeze-drying to obtain the liposome. The invention also covers the application of the liposome in treating renal failure. In the invention, through the combination of natural extracts and the combination of a specific composition and liposome administration, the components generate a synergistic effect, and the pharmaceutical composition has a remarkable treatment effect on renal failure, especially chronic renal failure.

The invention relates to the technical field of traditional Chinese medicine, and particularly discloses a traditional Chinese medicine monomer composition for chronic renal failure and application thereof. The traditional Chinese medicine monomer composition is prepared from the following raw materials in molar ratio: 9.5 to 40 mol of liquiritigenin, 3.5 to 9.5 mol of ginsenoside Rg2, 1 to 4 mol of quercetin, 0.5 to 3.5 mol of tanshinone IIA and 1 to 5 mol of baicalin. The invention further discloses application of the traditional Chinese medicine monomer composition in preparation of a preparation for chronic renal failure and application of the traditional Chinese medicine monomer composition in preparation of a medicine for chronic renal failure. The traditional Chinese medicine monomer composition has good in-vivo anti-inflammatory and anti-renal fibrosis activity, can significantly improve the renal function of chronic renal failure animals, and has a good application prospect.

The invention provides a combined dialysis nursing bed for the nephrology department, and relates to the technical field of chronic renal failure nursing. The left side and the right side of the top of the nursing bed body are each rotationally provided with an extension bed board. Four supporting sleeves in two groups are fixed on the inner wall of the top of the nursing bed main body, and an expansion bed board bracket is slidably mounted on each of the two groups of supporting sleeves; a double-head motor is further fixed on the inner wall of the top of the nursing bed main body; bracket adjusting screw rods are fixed on main shafts on the left side and the right side of the double-head motor; a heating block is fixed to the front side of the top of the upper heating bracket, and a dialysis tube limiting block is installed among the four guide rods in a sliding mode. When the nursing bed is not used, the expansion bed plates can be rotated downwards to be folded on the left side and the right side of the nursing bed body, the overall length of the nursing bed is shortened, therefore, the occupied space during folding is saved, dialysate about to flow into the abdominal cavity of a patient can be heated and subjected to heat preservation, and the comfort of the patient is improved.

A Cs-4 fermentation mycelium heteropolysaccharide, a preparation method and use thereof, the polysaccharide structure is as shown below, n is selected from 6-104, the polysaccharide can be used for preventing or treating chronic renal failure, inhibiting immune rejection, preventing or treating hyperlipidemia, preventing or treating acute kidney injury.

This invention discloses a metal-coordinated iohexol nanoparticle, its preparation method, and its applications. The metal-coordinated iohexol nanoparticles of this invention are prepared by reacting a metal salt with iohexol in an organic medium; the particle size range of the metal-coordinated iohexol nanoparticles is 50-100 nm. This invention synthesizes metal-coordinated iohexol nanoparticles via a one-pot method, which is simple and does not require multiple reaction steps. The metal-coordinated iohexol nanoparticles prepared by this invention mainly accumulate in the liver, with only a small amount accumulating in the kidneys. They can significantly reduce the nephrotoxicity of chronic renal failure model mice after CT imaging, and exhibit good biocompatibility and almost no cytotoxicity in vitro.

Use of hydronidone in the preparation of a medicament for treating chronic renal failure patients such as by preventing and / or treating chronic renal failure.

As a compound that can be used as a therapeutic or preventative agent for diseases involving TRPC6, such as nephrotic syndrome, membranous nephropathy, acute renal failure, sepsis, chronic renal failure, diabetic nephropathy, pulmonary hypertension, acute lung injury, heart failure, malignant tumors, and muscular dystrophy, a compound of formula (I) or a pharmaceutically acceptable salt thereof is provided (where Ar... 1 Ar 2 X 1 ~X 3 R 1 R 3 R 7 R 8 and L 1 L 2 (As defined in the instruction manual).