139 results about "Liquiritigenin" patented technology

The invention relates to a quality detection method of a traditional Chinese medicine preparation. The method comprises the following steps: respectively taking gallic acid, albiflorin, paeoniflorin,ferulic acid, liquiritin, beta-ecdysterone, senkyunolide I, glycyrrhizin, cinnamic acid, cinnamyl aldehyde, paeonol, ammonium glycyrrhizinate and ligustilide as reference substances, and establishinga fingerprint spectrum of the traditional Chinese medicine preparation by adopting high performance liquid chromatography; identifying Chinese angelica, the rhizome of chuanxiong, radix paeoniae alba,moutan bark, ginseng, cassia bark, licorice root and the root of bidentate achyranthes of the traditional Chinese medicine preparation by adopting thin-layer chromatography. The traditional Chinese medicine preparation is prepared by using the following raw materials: Chinese angelica, the rhizome of chuanxiong, radix paeoniae alba, cassia bark, moutan bark, zedoray rhizome, ginseng, licorice root and the root of bidentate achyranthes. With the two detection ways, comprehensive quality evaluation can be conducted on the meridian-warming decoction traditional Chinese medicine preparation. Themethod is simple, convenient, high in accuracy and high in reproducibility; a scientific basis can be provided for quality detection and evaluation of the meridian-warming decoction traditional Chinese medicine preparation, and the product quality is effectively controlled.

A synergistic clean extraction method of effective components in licorice root adopts a solvent to synchronously extract the effective components in licorice root in order to obtain a total extract product, and the total extract product is separated one by one according to physical and chemical properties of all the components. The method comprises the following steps: 1, preparing the total extract product of the licorice root; 2, separating water-soluble and fat-soluble components; 3, separating glycyrrhizic acid from licorice pigments, licorice glucose and licorice polysaccharides in the water-soluble components; 4, separating the licorice pigments from the licorice glucose and the licorice polysaccharides; 5, separating the licorice glucose from the licorice polysaccharides; 6, separating and purifying glabridin in the fat-soluble components; 7, separating and purifying liquiritin and isoliquiritin in the fat-soluble components; 8, separating and purifying isoliquiritigenin and liquiritigenin in the fat-soluble components; 9, separating and purifying licochalcone A in the fat-soluble components; 10, separating and purifying licorice lignin in the fat-soluble components; and 11, separating and purifying licorice cellulose in the fat-soluble components.

The invention discloses a method used for separating and identifying flavonoid matters in tobacco by adopting liquid chromatography-mass spectrography. The method comprises the following steps: a sample is ground and dried, an extractant is added according to the standard that 0.1 ml of the extractant is added into 1 mg of the sample for extraction and centrifugation, a supernatant liquor is collected, water and chloroform are added according to the standard that 0.5 ml of the water and 1 ml of the chloroform are added into 1 ml of the supernatant liquor for centrifugation, and the supernatant liquor is collected for analysis; 153+ and 151- are adopted as characteristic ions for scanning, parent ions are extracted for second level mass spectrum scanning, and an obtained spectrogram is compared with a spectral library to determine a chemical structure and verified through a reference substance; the molecules and ions of the identified matters and myricetin, dihydromyricetin, catechinic acid / epicatechin, daidzein, glycitein and glycyrrhizin / isoliquiritigenin are adopted as characteristic ions for scanning, the molecules and ions of the searched glycosylation flavonoid matters are used as the parent ions for the second level mass spectrum scanning, an obtained spectrogram is compared with the spectral library to determine a chemical structure and verified through the reference substance. According to the invention, the method is suitable for the analyzing and detecting micro even trace flavonoid matters.

The present invention is compound interferon inducing agent lozenge, relates to biomedicine engineering, and aims at providing lozenge capable of inducing body to generate endogenous interferon and with high curative effect, less side effect, small dosage and wide application. Each of the compound interferon inducing agent lozenge contains attenuated Newcastle disease virus vaccine or deactivated Newcastle disease virus vaccine 10-120 hemagglutination units, astragalus root 1-2000 mg, liquiritigenin 1-1000 mg, supplementary material and stabilizer. The compound interferon inducing agent lozenge is suitable for preventing SARS and other viral infectious respiratory tract diseases, and has also auxiliary treatment effect on various kinds of tumor, hepatitis B and hepatitis C.

The invention relates to a preparation method of a composite probiotic ice cream. The preparation method comprises the following steps of (1) weighing raw materials according to the formula: whole milk powder, soybean milk powder, water, cane sugar, beta-cyclodextrin, soybean protein powder, inulin, honeysuckle flower powder, Chinese wolfberry fruit powder and liquiritigenin for standby application; and (2) uniformly mixing and stirring the weighed raw materials in step (1), then performing homogenizing, performing sterilization and performing ageing to obtain an ice cream mixture, then adding0.003-0.008 part of composite probiotics to the ice cream mixture, performing uniform stirring to obtain a mixture, sending the mixture to a condensing and freezing machine for condensing and freezing, after condensing and freezing, performing filling, and performing hardening, so as to obtain the probiotic ice cream. The ice cream made by the preparation method is rich in nutrition, various probiotics and traditional Chinese medicine components, and has good health-care functions. According to the method, the ice cream is compounded from specific components in specific parts by weight, so that the survival rate of probiotics for the probiotic ice cream in the preparation and preservation process can be increased, and normal exertion of the health-care functions of the probiotic ice creamcan be guaranteed.

The technical field of the invention relates to preparation of a drug preparation method with liquiritigenin and combination containing liquiritigenin which is used to treat senile dementia and Parkinson disease. The liquiritigenin is added with excipient and processed into agents such as capsules, tablets, granules and injection, etc. The liquiritigenin has protection and nutrition functions to neurons and has no obvious female activity, thereby being capable of improving memory ability of dementia mouse and adlibitum sports ability of Parkinson disease model mouse.

The invention relates to anticancer liquiritigenin oral preparation and injection preparation, and a preparation method thereof, belonging to a medical technology field. The oral preparation comprises a particulate agent, tablets, capsules, pills and softgel, and the injection preparation comprises small hydro-acupuncture, freeze-dried powder injection, glucose injection and sodium chloride injection. The liquiritigenin oral preparation contains 0.1-100g liquiritigenin per 1000 preparation unit, and the injection preparation contains 0.1-100g liquiritigenin per 1000mL. Pharmaceutic adjuvants contain a diluent, a wetting agent, a disintegrating agent, a flow aid, a cosolvent, an excipient and an osmotic pressure regulator. The liquiritigenin preparation provided by the invention is safe and reliable, and has functions for preventing and treating cancers. And the anticancer medicament is used for preventing and treating lung cancer, liver cancer, stomach cancer, colorectal carcinoma, leukemia, etc., and is a new and effective anticancer medicine.

The invention discloses finely cut tobacco leaves with flavonoid compound essence for cigarettes and a method for preparing the finely cut tobacco leaves. The method includes weighing adhesive with the weight of 0.1%-1% of the weight of the flavonoid compound essence; dissolving the adhesive in water and then adding the dissolved adhesive into the flavonoid compound essence; uniformly stirring the dissolved adhesive and the flavonoid compound essence to obtain soft materials; extruding the soft materials by the aid of an extruder to obtain thin and long strips; rounding the strips by the aid of a rounder; drying the strips to obtain the finely cut tobacco leaves with the flavonoid compound essence. The flavonoid compound essence comprises, by weight, 20%-50% of liquiritigenin, 20%-50% of eugenol, 10%-40% of luteolin and 5%-20% of naringin. The finely cut tobacco leaves with the flavonoid compound essence and the method have the advantages that the finely cut tobacco leaves have obvious merits in the aspect of reducing phenol in smoke, the phenol reduction rate can reach 15-45%, and the free radical reduction rate is 8-25%; the flavonoid compound essence has excellent natural smell and can be added to a cigarette holder, so that the cigarettes can have unique and strong extra aroma.

The invention relates to a method for controlling quality of a liquorice medicinal material and a liquorice preparation. The method concretely relates to the step of simultaneously determining the content of the liquorice medicinal material and the content of six main active ingredients, namely liquiritin, isoliquiritin, liquiritigenin, isoliquiritigenin, glycyrrhizic acid and glycyrrhetinic acid in the liquorice preparation by utilizing a high performance liquid chromatography. A new method for controlling the quality of the liquorice and the liquorice preparation is established and the six main active ingredients, namely liquiritin, isoliquiritin, liquiritigenin, isoliquiritigenin, glycyrrhizic acid and glycyrrhetinic acid are quantitatively determined simultaneously by utilizing the high performance liquid chromatography. Confirmed by methodological investigation and test, the method is simple and convenient, correct in result and good in reproducibility, the defect of the existing quality control is overcome, and the quality control on the liquorice and the liquorice preparation is perfect and scientific.

The invention provides a full-function facial mask. The facial mask comprises the following components in percentage by mass: 0.01-2 percent of hyaluronic acid, 0.01-1 percent of reduced glutathione, 0.01-2 percent of L-vitamin C, 0.01-2 percent of tranexamic acid, 0.01-2 percent of liquiritigenin, 0.01-5 percent of vitamin E, 0.01-1 percent of EGF lyophilized powder, 0.01-2 percent of active peptide, 0.01-3 percent of SOD, 0.01-2 percent of arbutin, 0.1-2 percent of allantoin, 0.5-5 percent of glycerinum, 0.5-5 percent of propylene glycol and the balance of water, wherein the effective components are independently embedded with liposome or coated with nano-microcapsules before being mixed. The activated effective components of the facial mask are independently coated or embedded with transporters, and are delivered to the corium layer or the superficial corium layer by virtue of transportation of the transporters to achieve the effects of quadruple whitening, triple repairing and double moistening.