14 results about "Arctiin" patented technology

The present invention discloses a method for constructing a fingerprint of Gualou Niu Bang decoction, relating to the technical field of analytical chemistry. The method is simple and has high precision, stability, and repeatability. Determination revealed that seven components, including geniposide, liquiritin, hesperidin, arctiin, baicalin, melaleucalyptol A-7-O-β-D-glucuronide, and wogonin, can be used as common characteristic peaks in the fingerprint of Gualou Niu Bang decoction for identification research.

The invention discloses a platelet increasing capsule characteristic chromatogram and a construction method and application thereof, and belongs to the technical field of quality control of traditional Chinese medicine compound preparations. According to the method, 13 control components including gallic acid, catechin, paeoniflorin, forsythiaside B, benzoic acid, astragalus smicus glycoside, forsythin, arctiin, liquiritigenin, benzoyl paeoniflorin, paeonol, arctigenin and indirubin are selected, a high performance liquid chromatography-mass spectrometry technology is applied, multiple batches of preparation samples are analyzed, and the content of the components in the preparation samples is determined. And establishing a characteristic spectrum of the chemical components. Compared with a traditional method, the technology has good precision and reproducibility, the data result is accurate and reliable, meanwhile, the technology can identify the 13 components at the same time under the same chromatographic condition, the analysis efficiency is remarkably improved, synchronous monitoring of multiple effective components is achieved, and the consistency and stability of the preparation quality can be guaranteed.

The invention belongs to the technical field of detection, and discloses a method for detecting the content of five components in a traditional Chinese medicine preparation child heat-clearing and lung-benefiting oral liquid. According to the method, the contents of five active ingredients, namely ephedrine hydrochloride, pseudoephedrine hydrochloride, tectoridin, forsythin and arctiin, in the oral liquid for clearing heat and benefiting lung for children are simultaneously detected by adopting a multi-wavelength switching method through a specific solvent and chromatographic conditions. Compared with the prior art, the method has the advantages that the problems of single component, long detection period, high labor and reagent cost and the like in content determination of the oral liquid for clearing heat and benefiting lung for children are solved, the method is simple, convenient, high in specificity, good in repeatability and accurate in result, and reference can be provided for process research, quality guarantee and quality standard improvement of the oral liquid for clearing heat and benefiting lung for children.

This invention belongs to the field of novel pharmaceutical uses, and more specifically, relates to the application of arctiin in the preparation of drugs for treating porcine reproductive and respiratory syndrome (PRRS). This invention is the first to discover that arctiin has a significant antiviral effect against PRRSV, and demonstrates through Western blotting and qRT-PCR techniques at multiple levels that arctiin can significantly inhibit PRRSV infection and replication, exhibiting significant anti-PRRSV activity. It can be used to prepare drugs for treating PRRSV, and also for preparing drugs to treat PRRSV infection.

The invention discloses three diaryl butyrolactone lignan compounds in saussurea medusa as well as an extraction and separation method and application of the diaryl butyrolactone lignan compounds, and belongs to the technical field of extraction and separation of traditional Chinese medicines. The molecular formulas of the three lignan compounds are respectively as follows: C27H34O11 (arctiin), C21H24O6 (arctigenin) and C42H46O12 (arctigenin), and the molecular formulas of the three lignan compounds are respectively as follows: C27H34O11 (arctigenin), C21H24O6 (arctigenin) and C42H46O12 ( According to the invention, ethanol extraction, extraction with different polar solvents, silica gel column chromatography and high performance liquid chromatography are adopted for separation, purification and preparation, and ESIMS, 1H-NMR, 13C-NMR, HSQC and other spectrums are adopted for identifying the structure. The diaryl butyrolactone lignan compounds with important medicinal values are efficiently separated from saussurea medusa, and a new source and a material basis are provided for further research and application of the diaryl butyrolactone lignan compounds.

The utility model discloses an arctiin extracting and purifying device which comprises a processing barrel, a fixing box, a solution separating mechanism, a lifting assembly, a squeezing assembly, a connecting frame, a fixing block and an extracting and purifying mechanism, and the solution separating mechanism comprises a threaded rod, a driving motor, a guide rod, a nut seat, a connecting rod, a rotating shaft support, a squeezing disc, a filter screen, a telescopic air cylinder and a supporting disc. The extraction and purification mechanism comprises a purification barrel, a fixed table, a support plate and a filter layer support table. The utility model belongs to the technical field of arctiin purification, a nut seat can be driven to move by starting a driving motor, so that a squeezing disc is conveniently driven to descend to sufficiently squeeze crushed burdock on a filter screen to thoroughly separate out a solution, and a telescopic cylinder is started to extend to drive a supporting disc to be separated from the filter screen, so that the separated solution can flow out conveniently; different types of filter layers are fixedly placed on each group of filter layer support table, so that arctiin can be conveniently and finely extracted and purified from a flowing burdock precipitation solution.

The invention discloses a hermetia illucens sand organic fertilizer based on kitchen garbage as well as a preparation method and application thereof, and relates to the technical field of biology. The hermetia illucens insect sand organic fertilizer is prepared from the following components in parts by weight: 90 to 110 parts of hermetia illucens insect sand, 11 to 15 parts of corn straw powder, 8 to 12 parts of sawdust and 2 to 2.5 parts of bioactive substances, the bioactive substances comprise arctiin and magnolol; the mass ratio of arctiin to magnolol is (1-9): 9. According to the organic fertilizer and the preparation method thereof, the double breakthrough of efficient recycling of the kitchen garbage and high-value utilization of the organic fertilizer is achieved, the organic fertilizer provided by the invention can remarkably promote plant growth and prevent and treat clubroot of plants, the problems of chemical pesticide residues and drug resistance of pathogenic bacteria can be avoided, and an effective solution is provided for recycling of the kitchen garbage and development of green agriculture.

The invention relates to the technical field of traditional Chinese medicine compositions, in particular to sugar-free traditional Chinese medicine granules for treating wind-heat type common cold and a preparation method of the sugar-free traditional Chinese medicine granules. The sugar-free traditional Chinese medicine granules for treating wind-heat type common cold are prepared by extracting mint, schizonepeta spike, burdock, radix isatidis, fructus forsythiae, folium mori, rhizoma phragmitis, chrysanthemum, semen armeniacae amarae, ramulus mori and medicated leaven as raw materials. The weight part ratio of the raw materials is 3: (2-3): 3: (4-5): 3: 3: 3: 3: 3: 3: 3: 3; wherein the burdock extract is an alcohol extract, and the content of arctiin in the alcohol extract is not less than 10% by mass. The sugar-free traditional Chinese medicine granules for treating wind-heat type common cold have higher arctiin content, and have advantages in extraction of burdock and utilization of active ingredients compared with wind-heat type common cold granules prepared by a traditional process.

The invention provides a quality detection method of an anti-pharyngitis traditional Chinese medicine compound extract, which adopts high performance liquid chromatography for qualitative and quantitative analysis of iridin and arctiin, and adopts ultraviolet-visible spectrophotometry for quantitative analysis of total flavonoids. Furthermore, comprehensive evaluation is carried out by taking the contents of iridin, arctiin and total flavonoids as well as the yield of the extract as indexes, the extraction time and the solvent amount which have great influence on the water extraction effect are investigated, and the extraction process of the anti-pharyngitis traditional Chinese medicine compound extract is optimized; the high performance liquid chromatography and the ultraviolet-visible spectrophotometric method are good in linear relation, high in precision, good in repeatability and accurate in determination result, and qualitative and quantitative analysis are combined to lay a foundation for establishing the quality standard of the anti-pharyngitis traditional Chinese medicine compound extract.

The invention discloses a method for synchronously and quantitatively detecting 14 components in fructus forsythiae based on ultra-high performance liquid chromatography, and belongs to the technical field of quality detection of traditional Chinese medicinal materials. Dissolving the fructus forsythiae powder in a methanol aqueous solution, and extracting to obtain a to-be-detected sample; the method comprises the following steps: respectively preparing a standard solution and a mixed standard solution by taking chlorogenic acid, forsythiaside I, forsythiaside B, rutin, forsythiaside A, forsythiaside H, tectoridin, pinoresinol-beta-D-glucoside, naringin, forsythin, arctiin, quercetin, kaempferol and forsythiaside as standard substances; the method comprises the following steps: acquiring a standard curve corresponding to each standard substance, a peak position and a chromatographic result of a to-be-detected sample solution through ultra-high performance liquid chromatography, and substituting the chromatographic result into a standard curve equation of the standard substance; and calculating the contents of chlorogenic acid, forsythiaside I, forsythiaside B, rutin, forsythiaside A, forsythiaside H, tectoridin, pinoresinol-beta-D-glucoside, naringin, forsythin, arctiin, quercetin, kaempferol and forsythiaside in the sample to be detected.

This invention discloses a quality testing method for pediatric throat-clearing granules, belonging to the field of traditional Chinese medicine preparation quality control technology. The method optimizes the identification methods for indigo naturalis and burdock seed using thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC), and adds identification methods for dandelion, scrophularia, and forsythia. Furthermore, HPLC is used to simultaneously determine the content of arctiin and forsythoside. This invention enables quality control of the five medicinal materials in pediatric throat-clearing granules, thus allowing for more effective and comprehensive control and evaluation of the quality of this traditional Chinese medicine preparation. Moreover, this method has advantages such as safety, durability, and good repeatability.

The application provides a quality detection method of an anti-pharyngitis traditional Chinese medicine compound extract, adopts high performance liquid chromatography to qualitatively and quantitatively analyze iriflorend and arctiin, adopts ultraviolet-visible spectrophotometry to quantitatively analyze total flavones, further comprehensively evaluates indexes of the contents of iriflorend and arctiin, the content of total flavones and the yield of the extract, investigates extraction time and solvent amount which have great influence on water extraction effect, and optimizes the extraction process of the anti-pharyngitis traditional Chinese medicine compound extract; the high performance liquid chromatography and the ultraviolet-visible spectrophotometry have good linear relationship, high precision, good repeatability and accurate determination results, and the combination of qualitative and quantitative analysis lays a foundation for the establishment of the quality standard of the anti-pharyngitis traditional Chinese medicine compound extract.

The present application provides a preparation that can be used for colitis, comprising arctiin; chitosan; and arctiin and chitosan connected via a diselenide bond. A method for preparing the aforementioned preparation is also provided. Compared to other existing technologies with complex preparation processes and inconvenient administration methods, the preparation method of the present application is simple, has a stable yield, and is convenient and quick to synthesize in only two steps. The prepared hydrogel also uses a safe and non-toxic natural non-toxic cross-linking agent as a cross-linking agent, has good efficacy, can be administered orally, and has better patient compliance than rectal administration. It has significant advantages and extremely high development potential for clinical development and use.

The invention discloses a method for preparing arctigenin through dynamic regulation and control fermentation, and belongs to the technical field of natural active ingredient extraction. In order to solve the technical problem that the extraction efficiency of arctigenin is poor in the prior art, the invention provides a method for preparing arctigenin through dynamic regulation and control fermentation. According to the method, the arctigenin is prepared by dynamically regulating and controlling fermentation through a multi-path replaceable process, and the method comprises the following steps: dynamically regulating and controlling fermentation in a time-sharing manner, and dynamically regulating and controlling the feeding speed, the stirring speed and the fermentation temperature; the biomass of the thalli is improved by selecting a carbon source adaptive to the metabolic characteristics of the strains; dynamic time-sharing fermentation regulation and control is combined with dynamic regulation and control of material supplementation, stirring rate and fermentation temperature, so that the yield of arctigenin is increased. According to the method for preparing arctigenin through dynamic regulation and control fermentation, the conversion efficiency of arctigenin is improved to the maximum extent, the waste rate is reduced, and energy consumption and production cost are effectively saved.