70 results about "Pharyngitis" patented technology

The invention provides a strain of high-temperature-resistant and inflammation-relieving Witzia ciliaris and an application thereof, the high-temperature-resistant and inflammation-relieving Witzia ciliaris is Witzia ciliaris CN985 and is preserved in the China Center for Type Culture Collection (CCTCC), the preservation date is April 7, 2024, and the preservation number is CCTCC NO: M 2024641. The invention further provides a preparation method of the high-temperature-resistant and inflammation-relieving Witzia ciliaris strain for preventing and treating inflammation of the high-temperature-resistant and inflammation-relieving Witzia ciliaris strain for preventing and treating inflammation of the high-temperature-resistant and inflammation-relieving Witzia ciliaris strain. The invention provides a brand new strain of Witzia ciliaris CN985, which is resistant to high temperature, has better acid resistance and bile resistance, and has no hemolysis risk when being applied to a human body. The Witzia coagulans CN985 has excellent antibacterial performance, and especially can significantly inhibit streptococcus pyogenes, salmonella enteritidis and / or group B streptococcus; besides, experimental results show that the Witzia ciliaris CN985 can relieve enteritis, improve the immunity of the organism and relieve pharyngitis, and especially when the Witzia ciliaris CN985 and the phytobacterium plantarum CE18 are combined for use, the Witzia ciliaris CN985 and the phytobacterium plantarum CE18 have a synergistic interaction effect, so that the relieving effect on enteritis can be remarkably improved.

A method for automated discrimination between Group A Streptococcus (GAS) and non-GAS pharyngitis, including segmenting and tracking a region of interest including a throat in a displayed image or video; automatically acquiring an input image based on the segmentation of the displayed image or video; receiving at least one patient symptom; removing shadows in the input image; segmenting the input image to isolate the region of interest including the throat; determining an image quality of the isolated region of interest; and classifying, via a machine learning classifier, pharyngitis in the isolated region of interest as being caused by GAS or a non-GAS cause based on the isolated region of interest and the at least one patient symptom.

The invention discloses preparation of an anti-chronic pharyngitis microcapsule medicine and application of the anti-chronic pharyngitis microcapsule medicine in tipping paper for cigarettes, the medicine is MF-GA / IL (at) MPN, and the medicine is composed of an ionic liquid (IL) as an internal carrier and a microcapsule carrier with a metal phenol network (MPN) as a shell; wherein the metal phenol network is formed by aluminum ions and mangiferin through a coordination reaction, and the ionic liquid is CAGE ILs formed by vanillin and choline. The combination of mangiferin and glycyrrhizic acid is used as a strategy for treating chronic pharyngitis, it is found that the effective loaded MF-GA / IL-coated MPN microcapsule preparation is obtained by packaging the two drugs including mangiferin and glycyrrhizic acid with the ionic liquid as the core and the metal phenol network as the shell, the tissue permeability of the drugs is improved, a certain slow release effect is achieved, and the effect of treating chronic pharyngitis is achieved. The bioavailability of mangiferin and glycyrrhizic acid is improved, and the anti-inflammatory activity effect is better achieved.

1. The name of the product of this design: packaging box (pharyngitis tablets). 2. Purpose of this design product: used for packaging medicines. 3. The design key point of this appearance design product lies in the combination of shape and pattern. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a pharyngitis adjuvant therapy traditional Chinese medicine formula capable of clearing and nourishing throat and a preparation method thereof, and the pharyngitis adjuvant therapy traditional Chinese medicine formula comprises radix pseudostellariae, poria cocos, Chinese yam, radix scrophulariae, honeysuckle, lily, radix rehmanniae, radix rehmanniae preparata, radix ophiopogonis, folium mori, scutellaria baicalensis, platycodon grandiflorum, coptis chinensis, mint, radix saposhnikoviae, dark plum, pericarpium citri reticulatae, scaphium scaphigerum, rhizoma phragmitis and liquorice. According to the invention, a layer-by-layer self-assembly technology is adopted, a slow-release coating with a multi-layer structure is constructed on the surfaces of drug particles, and the coating can control the release speed of the drug, so that the drug is continuously released at the throat part, the action time of the drug is prolonged, and the bioavailability and the treatment effect of the drug are improved; the structure not only enhances the stability of the coating, but also further controls the release speed of the medicine, so that the medicine is released more stably and lastingly.

The invention discloses a mineralization repair type oral cavity and throat nursing material for middle-aged and elderly people and a preparation method thereof. The nursing material consists of a core mineralization precursor, a function relieving component and an auxiliary synergistic component, wherein the core mineralization precursor is a biocompatible mineralization matrix of modified hydroxyapatite loaded carbon nitride quantum dots, and is used for realizing mucous membrane mineralization repair; the functional soothing component is a mixture of dihydromyricetin, a licorice extract and a menthol-beta-cyclodextrin inclusion compound, and has mild soothing and anti-inflammatory effects; the auxiliary synergistic component is a mixture of bovine serum albumin and a gamma-polyglutamic acid-g-methoxypolyethylene glycol derivative, and a mineralized precursor is stabilized and mucous membrane adhesion is enhanced by constructing a protein nanocage structure. By optimizing the process, the production efficiency and stability are improved, the biological safety is enhanced, the nursing requirements of middle-aged and elderly oral cavity and throat sensitive mucous membranes are better met, and the oral cavity and throat sensitive mucous membrane repairing gel is suitable for oral cavity mucous membrane sensitive repairing and chronic pharyngitis auxiliary nursing.

The invention relates to a recombinant human interferon alpha1b solution as well as a preparation method and application thereof, and belongs to the technical field of pharmaceutical preparations. The technical problems that in the prior art, the production cost is increased and the risk of blood virus infection exists due to the fact that the recombinant human alpha interferon spray is prepared from human albumin are solved. The recombinant human interferon alpha 1b solution comprises recombinant human interferon alpha 1b, gelatin, a pH regulator, a surfactant, a bacteriostatic agent and water, and further comprises one or more of an antioxidant, a thickening agent and an osmotic pressure regulator. The recombinant human interferon alpha1b solution is good in product quality and good in stability, can be stored for at least 24 months at the temperature of 2-8 DEG C under the dark condition, and can be stably stored for 3 months under the common indoor condition; the compound can be applied to preparation of medicines for treating or preventing diseases (herpes simplex, herpangina of children, hand-foot-and-mouth disease and respiratory diseases) caused by virus infection.

The utility model discloses a traditional Chinese medicine atomization device for pharyngitis, and provides the traditional Chinese medicine atomization device for pharyngitis, which is adjustable in mist temperature and good in using effect. Comprising an atomization frame, one end of the atomization frame is provided with an atomization box, the other end of the atomization frame is connected with a cooling column, the atomization box is connected with an atomization pipe, the atomization pipe is wound on the cooling column, the outer side of the middle of the cooling column is connected with a movable heat preservation sleeve, and the end of the atomization pipe is connected with an atomization mask. The cooling device has the advantages that the cooling effect of the arranged cooling column can be adjusted through the cooling pump, and the using effect is improved; the atomization pipe is spirally installed in the cooling groove of the cooling column, the atomization pipe can be cooled through the cooling column, and scalding is avoided.

The invention belongs to the technical field of traditional Chinese medicines, and mainly relates to a traditional Chinese medicine composition for clearing heat from throat, a traditional Chinese medicine preparation and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicines in parts by weight: 0.9 to 1.5 parts by weight of radix scrophulariae, 1.2 to 5.0 parts by weight of radix polygonati officinalis, 1.0 to 3.0 parts by weight of radix glehniae, 1.0 to 1.5 parts by weight of radix rehmanniae, 1.0 to 3.0 parts by weight of radix ophiopogonis, 1.5 to 6.0 parts by weight of gypsum and 0.5 to 3.0 parts by weight of liquorice root. The preparation method of the traditional Chinese medicine preparation comprises the working procedures of processing, burdening, extracting, concentrating, preparing a soft material, granulating, drying and finishing granules. The traditional Chinese medicine composition or the traditional Chinese medicine preparation for clearing heat from throat can relieve symptoms such as red and swollen pharynx, dry mouth and dry throat, pharyngalgia, pharynx itching, scorching fever, less phlegm and foreign body sensation of pharynx caused by heat evil, and has a remarkable curative effect on chronic pharyngitis. Through a unified preparation method, the accuracy of the quality and dosage of the used medicinal materials and the stability of the treatment effect are ensured.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating plateau chronic pharyngitis, which comprises the following raw materials in parts by weight: 2-20 parts of ginseng, 2-30 parts of astragalus membranaceus, 1-10 parts of dendrobe, 1-15 parts of medlar, 1-30 parts of bighead atractylodes rhizome, 1-18 parts of thunberg fritillary bulb, 2-30 parts of momordica grosvenori, 1-15 parts of pericarpium citri reticulatae, 1-15 parts of mint, 1-15 parts of honeysuckle and 1-20 parts of chrysanthemum. The traditional Chinese medicine composition for treating plateau chronic pharyngitis has the effects of tonifying qi and relieving sore-throat, is refreshing and pleasant in taste, can mildly and effectively act on the throat part, relieves dry itching, pain, chronic cough, hoarseness and the like, achieves the goal of integrating treatment, prevention and health care, and embodies the idea of treating diseases by traditional Chinese medicines.

Composition for use for the treatment and / or prevention of infections or lesions of the (oral) mucosa, in particular originating from at least one selected the group consisting of: perleche; scarlet fever; pharyngitis; acute necrotising ulcerative mucositis; impetigo contagiosa; chelitis glandularis apostem atosa; gingivostomatitis herpetica; herpes simplex; herpes stabistis recidivans; herpes zoster; hand-foot-mouth; human papilloma virus; HIV; oral candidiasis; oral lichen planus; lichen ruber planus; leukoplakia, erythroplakia; methicillin-resistant staphylococcus aureus; gingivitis / periodontitis; mucositis / peri- implantitis; alveolar osteolytis; wherein the composition comprises or consists of the following components: (a) polyhexanide (PHMB); (b) an organic or inorganic buffer different from a); (c) further additives; (d) optionally water.

This invention provides a traditional Chinese medicine compound for treating chronic pharyngitis, belonging to the field of biomedical technology. The invention comprises a self-formulated traditional Chinese medicine compound consisting of *Pearl Umbrella*, *Trichosanthes kirilowii*, *Sapindus mukorossi*, *Lycoperdon perlatum*, *Panax japonicus*, *Gnaphalium affine*, *Aster tataricus*, and prepared licorice root for the treatment of chronic pharyngitis. Addressing the complex pathogenesis of chronic pharyngitis, characterized by a mixture of deficiency and excess, phlegm and blood stasis, and yin deficiency, the ingredients in the compound are rationally combined and work synergistically to achieve the effects of promoting blood circulation without depleting yin, clearing heat without harming yang, resolving phlegm without hindering the spleen, nourishing yin without being cloying, combining tonification and purgation, using both warming and cooling methods, and treating both the root cause and the symptoms. This compound is suitable for the treatment and management of chronic pharyngitis.

The invention discloses a traditional Chinese medicine composition for treating chronic pharyngitis and application of the traditional Chinese medicine composition, and belongs to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition comprises the following components in parts by weight: 10-20 parts of radix glehniae, 10-20 parts of radix ophiopogonis, 10-20 parts of radix scrophulariae, 10-20 parts of radix salviae miltiorrhizae, 15-25 parts of radix rehmanniae, 15-25 parts of radix paeoniae rubra, 20-30 parts of rhizoma cimicifugae, 1-8 parts of liquorice and 10-20 parts of semen sesami nigrum. The traditional Chinese medicine composition blocks the case development of chronic pharyngitis from the two aspects of tonifying deficiency and removing stasis, plays a good role in treating chronic pharyngitis, and effectively solves the problems existing in the prior art.

Provided herein are formulations for use in enteral tube feeding, that contain one or more whole food-based ingredients, mineral nutrients, small molecules, and / or large molecules, the combination of which is effective to bind bile acids when administered to a subject in need thereof. The combination of crafted ingredients for tube feeding reduce symptoms of gastroesophageal reflux, vomiting, abdominal pain, irregular stooling (diarrhea or constipation) and to reduce organ damage including pneumonia, pharyngitis, aspiration, esophagitis, gastritis and enteritis.

Provided herein are pharmaceutical compositions, therapeutic combinations, devices and methods for treating, ameliorating, reversing, causing the remission of, and / or preventing (acting as a prophylaxis, or preventing the initiation of) an inflammatory bowel disorder (IBD) or inflammatory bowel disease (IBD), Ulcerative Colitis; Crohn's disease; J-pouch; fistulising Crohn's disease; a Colitis which can be microscopic, lymphocytic or collagenous; an eosinophilic colitis; indeterminate colitis; idiopathic colitis; diverticulosis and diverticulitis; relapsing diverticulitis; constipation associated inflammatory bowel disease and / or small intestinal bacterial overgrowth; Irritable Bowel Syndrome (IBS) with or without diarrhoea, constipation or pain predominant IBS; periodontitis; rheumatoid arthritis; respiratory infections, appendicitis, vascular disorders such as thrombophlebitis; bacteremia; osteomyelitis; septic shock; Alzheimer's disease; Lemierre syndrome (postanginal sepsis); colonic polyps or adenomas (optionally hyperplastic, adenomatous or serrated adenomas) or preventing the growth of colonic polyps or adenomas, bowl cancer, or metastases (optionally preventing the initiation or promotion of bowl cancer or metastasis); pharyngitis; otitis; sinusitis; and any disease, symptom or condition caused or exacerbated by a Fusobacteria (optionally, a F. nucleatum or F. varium) infection. In alternative embodiments, pharmaceutical compositions comprise rifaximin alone or in combination with other antibiotics or drugs.

The invention discloses an aerosol inhalant containing cannabidiol and application of the aerosol inhalant. The aerosol inhalant is prepared from the following components: 3.0 to 5.0 g of cannabidiol, 2.2 to 2.6 g of honeysuckle flower extract, 1.0 to 1.5 g of bamboo leaf extract, a proper amount of water for injection and 9.0 to 15.0 g of glycerol, and the volume of the water for injection is fixed to 1000ml. The aerosol inhalant can be used for preventing and treating sphagitis.

The invention provides a method for extracting kapur through compound bacterium fermentation, which comprises the following steps: drying leaves of kapur burmannii chvar.Borneol by microwaves, mixing and crushing to obtain leaf powder, adding a compound enzyme of xylanase, hemicellulase, lipase and pectinase for enzymolysis, taking a citric acid-sodium citrate buffer solution as a solvent, carrying out enzymolysis, heating for inactivation, filtering, washing, and drying to obtain a finished product. The borneol type cinnamomum burmannii leaves are obtained by fermenting the borneol type cinnamomum burmannii leaves with a complex microbial inoculant, extracting a fermentation product with an ionic liquid-ethanol mixed solution, extracting with petroleum ether, condensing and refluxing with absolute ethyl alcohol and performing vacuum drying to remove an organic solvent, the yield of the borneol type cinnamomum burmannii leaves is high, release of IFN-beta and IL-6 inflammatory mediators can be remarkably reduced, inflammatory response is relieved, and the borneol type cinnamomum burmannii leaves are prepared. The inflammation process is inhibited, the effect of treating or preventing chronic pharyngitis is achieved, and the effects of improving sleep and relieving emotion are achieved.

The invention provides a tobacco additive composition for relieving respiratory tract discomfort symptoms. The tobacco additive composition comprises daidzein and naringenin. The tobacco additive disclosed by the invention has unique characteristics. When the tobacco is ignited, the daidzein and the naringenin are not changed by combustion, but are directly converted into gaseous states, and are inhaled into the respiratory tract of a human body along with smoke generated by combustion of the tobacco. The characteristic specially exerts positive effects on chronic pharyngitis and pharyngolaryngitis, not only can relieve diseases and prevent diseases, but also can assist in treatment, is free of any complications after being used for a long time, and provides a solid guarantee for health and safety of a user. In the aspect of use experience, the additive enables tobacco products to be better in taste, and the additive is easily accepted by vast smokers.

The present invention discloses a traditional Chinese medicine composition with the effects of replenishing qi and drying dampness and its application. The present invention provides a new application of a known traditional Chinese medicine composition for blocking the carcinogenic transformation of colitis in the preparation of a drug for treating cough. The present invention also obtains a new traditional Chinese medicine composition by improvement on the basis of this formula, which not only has a cough-relieving effect, but also has a good therapeutic effect on the sticky phlegm accompanied by cough caused by respiratory tract infection, chronic obstructive pulmonary disease, pharyngitis and bronchitis.

The present invention belongs to the technical field of traditional Chinese medicine, and mainly relates to a traditional Chinese medicine composition for clearing the throat and relieving sore throat, a traditional Chinese medicine preparation, and their preparation methods and applications. The traditional Chinese medicine composition is composed of the following traditional Chinese medicines in parts by weight: 0.9-1.5 parts by weight of Scrophulariae Radix, 1.2-5.0 parts by weight of Polygonati Odorati Rhizoma, 1.0-3.0 parts by weight of Glehniae Radix, 1.0-1.5 parts by weight of Rehmanniae Radix, 1.0-3.0 parts by weight of Ophiopogonis Radix, 1.5-6.0 parts by weight of Gypsum Fibrosum, and 0.5-3.0 parts by weight of Glycyrrhizae Radix. The preparation method of the traditional Chinese medicine preparation includes processes of processing, proportioning, extraction, concentration, soft material preparation, granulation, drying, and sizing. The traditional Chinese medicine composition or preparation for clearing the throat and relieving sore throat can relieve symptoms such as red and swollen pharynx, dry mouth and throat, sore throat, itchy throat, burning sensation, less phlegm, and foreign body sensation in the pharynx caused by pathogenic heat, and shows significant curative effect on the treatment of chronic pharyngitis. Through a unified preparation method, the quality and dosage accuracy of the medicinal materials used are ensured, as well as the stability of the treatment effect.

The invention provides traditional Chinese medicinal liquor for treating pharyngitis and tonifying Yang and a preparation method thereof, and relates to the technical field of traditional Chinese medicinal liquor, the traditional Chinese medicinal liquor is prepared from the following raw materials: cistanche powder, licorice powder, wolfberry powder, red date powder, onion powder and edible white spirit; the cistanche powder has the effects of tonifying kidney yang and benefiting essence and blood; the Chinese wolfberry powder has the effects of nourishing kidney and liver and improving sexual function; the red date powder has the effects of tonifying middle-Jiao and Qi and nourishing blood and tranquilizing mind; the licorice powder can tonify spleen and qi, clear away heat and toxic materials and relieve pharyngitis symptoms; the onion powder is rich in various anti-inflammatory and sterilizing substances, and plays a role in regulating pharyngitis; the raw materials adopted by the invention are all natural materials, are reasonable in compatibility, small in side effect and low in cost, and are beneficial to relieving pharyngeal inflammation and pain, comprehensively conditioning sexual dysfunction and treating both symptoms and root causes after being matched with the edible white spirit.

The invention firstly discloses the composition for treating sphagitis. The composition is prepared from 30-40% of dendrobium officinale and 30-40% of fructus phyllanthi. And the balance of honey. Preparing the dendrobium officinale into superfine powder, preparing the fructus phyllanthi into superfine powder, and uniformly mixing the superfine powder with the honey to obtain the composition. The composition is mixed with a pharmaceutically common excipient to obtain the medicine for treating sphagitis. The medicine comprises but is not limited to tablets, capsules, pills and liquid preparations. The invention develops a novel natural formula preparation, and experiments prove that the preparation can effectively prevent and treat pharyngitis.

The invention discloses a traditional Chinese medicine composition with effects of tonifying qi and eliminating dampness and application of the traditional Chinese medicine composition. The invention provides a novel application of a known traditional Chinese medicine composition for blocking transformation of colitis cancer in preparation of a medicine for treating cough. The invention also obtains a new traditional Chinese medicine composition through improvement on the basis of the formula, and the traditional Chinese medicine composition not only has an antitussive effect, but also has a good treatment effect on sticky phlegm accompanied by cough caused by respiratory tract infection, chronic obstructive pulmonary disease, pharyngitis and bronchitis.

The invention provides spray liquid for clearing heat from throat. The spray liquid for clearing heat from throat comprises the following components in percentage by weight: 3%-8% of towel gourd extract, 2%-5% of litchi extract and 87%-95% of preserving fluid. The throat clearing spray liquid disclosed by the invention has the effect of relieving pharyngitis. After the lychee extract and the towel gourd extract are compounded, the anti-inflammatory effect of the towel gourd extract is remarkably enhanced, and the lychee extract and the towel gourd extract have a potential good clinical application prospect.

The present invention discloses an anti-inflammatory and antibacterial composition, and a preparation method and application thereof. The composition is obtained by compounding a turmeric plant extract and a Chinese herbal medicine extract, wherein the turmeric plant extract is a volatile oil extract of the turmeric plant; the Chinese herbal medicine extract contains houttuynia cordata extract, chrysanthemum extract, bupleurum extract, yew lily extract, andrographis paniculata extract, and capillaris extract; the properly matched composition has a significant synergistic effect and can enhance its anti-inflammatory and antibacterial effects. At the same time, the promotion of transdermal absorption of the composition was studied, and it was found that the piperine compounding scheme can significantly improve the transdermal absorption effect and improve the bioavailability of the composition. The anti-inflammatory and antibacterial composition of the present invention has the effects of clearing away heat and detoxifying, reducing swelling and draining pus, stopping bleeding and relieving pain, and anti-inflammatory and sterilizing. At the same time, it has the advantages of a short treatment course, high efficacy, no toxic side effects, no recurrence of the disease, and is not easy to develop drug resistance. It can be used to treat oral inflammation and pharyngitis.

The present invention addresses the problem of providing a novel technique for suppressing pharyngitis and restoring water swallowing reflex by using loxoprofen and / or a salt thereof. According to the present invention, provided is a pharmaceutical composition having a pharyngitis-inhibiting effect and containing at least one substance selected from the group consisting of loxoprofen, salts thereof, and hydrates thereof.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to traditional Chinese medicine granules for relieving sore-throat and clearing away lung-heat and a preparation method thereof. The granule is prepared from the following raw materials: honeysuckle flower, dried orange peel, Chinese olive, balloonflower root and licorice root, adopts a volatile oil extraction and water decoction synergistic enrichment technology, and realizes synergistic retention of volatile and water-soluble components through the steps of volatile oil independent extraction, low-temperature preservation, spray addition, low-temperature vacuum concentration and the like. The finished product is uniform in particle size, convenient to take, high in stability and suitable for chronic pharyngitis patients and people using sound for a long time. The traditional Chinese medicine composition solves the problems of active ingredient loss, poor stability and inconvenience in taking of traditional Chinese medicines, and has remarkable clinical application value.

The utility model belongs to the technical field of medical instruments, and particularly relates to a portable mouth and nose atomizer. The portable mouth-nose atomizer comprises an atomizer main body, a heating mechanism and a control mechanism, the atomizer body comprises a main machine box, a respirator arranged at the front end of the atomizer body and a liquid medicine box arranged on the main machine box. The main machine box comprises a mounting groove extending inwards from the top of the main machine box and an atomizing assembly arranged in the main machine box and communicated with the respirator. The heating mechanism is used for heating the liquid medicine box and comprises a heating sheet which is arranged at the bottom of the mounting groove and is opposite to the liquid storage chamber; the control mechanism is used for controlling the heating mechanism and the atomization assembly. Through cooperation of the atomizer body, the heating mechanism arranged on the main machine box and the control mechanism arranged on the main machine box, liquid medicine in the liquid medicine box is heated, so that the temperature of liquid medicine mist is increased, the temperature of the liquid medicine mist inhaled by a patient is appropriate, stimulation of low temperature to people can be effectively prevented, and the comfort of the patient is improved. The traditional Chinese medicine has a good treatment effect on patients suffering from rhinitis and pharyngitis.

The invention discloses a method for detecting a Wantongkang in-blood core bioactive component group and verification, serum, urine and excrement are collected as an experimental group after a preset time, and serum, urine and excrement of animals not given with Wantongkang are used as a control group; and detecting the experimental group and the control group by adopting liquid chromatography-mass spectrometry. The invention systematically analyzes the original components and metabolites of Wantongkang in blood plasma, urine and excrement of rats. 38 primordial components are detected in plasma, 48 urine and 89 excrement. The terpenoids may form a core pharmacodynamic material basis of WTYK for treating pharyngitis. A metabolic conversion path of picria fel-terrae glycoside IA, rosmarinic acid, isofraxidin, caffeic acid and apigenin-7-O-glucuronide is constructed through metabolic conversion analysis, and active metabolites of picria fel-terrae glycoside IA, rosmarinic acid, isofraxidin, caffeic acid and The network pharmacological research based on the in-blood component reveals that the WTYK plays a therapeutic role in treating the pharyngitis mainly by regulating key signal channels such as PI3K-Akt, MAPK, TNF, JAK-STAT and NF-kB, wherein the NF-kB signal channel is closely related to the occurrence and development of the pharyngitis.

The invention provides a tobacco additive composition for preventing and treating sphagitis. The tobacco additive composition comprises isorhamnetin and naringenin. The tobacco additive has unique properties, when tobacco is ignited, isorhamnetin and naringenin are not changed through a combustion mode but are converted into a gaseous state, and the isorhamnetin and the naringenin enter the respiratory tract of the human body along with gas generated by tobacco combustion. Due to the characteristic, the traditional Chinese medicine composition can play a positive role in chronic pharyngitis and pharyngolaryngitis, effectively relieve symptoms, prevent diseases and assist the treatment process, does not cause any complications after being used for a long time, and greatly guarantees the health and safety of a user. From the perspective of use experience, the tobacco product is endowed with good taste by the additive, and the additive can be appreciated and accepted by the majority of smokers.