36 results about "Pharyngitis" patented technology

The invention provides a strain of high-temperature-resistant and inflammation-relieving Witzia ciliaris and an application thereof, the high-temperature-resistant and inflammation-relieving Witzia ciliaris is Witzia ciliaris CN985 and is preserved in the China Center for Type Culture Collection (CCTCC), the preservation date is April 7, 2024, and the preservation number is CCTCC NO: M 2024641. The invention further provides a preparation method of the high-temperature-resistant and inflammation-relieving Witzia ciliaris strain for preventing and treating inflammation of the high-temperature-resistant and inflammation-relieving Witzia ciliaris strain for preventing and treating inflammation of the high-temperature-resistant and inflammation-relieving Witzia ciliaris strain. The invention provides a brand new strain of Witzia ciliaris CN985, which is resistant to high temperature, has better acid resistance and bile resistance, and has no hemolysis risk when being applied to a human body. The Witzia coagulans CN985 has excellent antibacterial performance, and especially can significantly inhibit streptococcus pyogenes, salmonella enteritidis and / or group B streptococcus; besides, experimental results show that the Witzia ciliaris CN985 can relieve enteritis, improve the immunity of the organism and relieve pharyngitis, and especially when the Witzia ciliaris CN985 and the phytobacterium plantarum CE18 are combined for use, the Witzia ciliaris CN985 and the phytobacterium plantarum CE18 have a synergistic interaction effect, so that the relieving effect on enteritis can be remarkably improved.

The invention discloses preparation of an anti-chronic pharyngitis microcapsule medicine and application of the anti-chronic pharyngitis microcapsule medicine in tipping paper for cigarettes, the medicine is MF-GA / IL (at) MPN, and the medicine is composed of an ionic liquid (IL) as an internal carrier and a microcapsule carrier with a metal phenol network (MPN) as a shell; wherein the metal phenol network is formed by aluminum ions and mangiferin through a coordination reaction, and the ionic liquid is CAGE ILs formed by vanillin and choline. The combination of mangiferin and glycyrrhizic acid is used as a strategy for treating chronic pharyngitis, it is found that the effective loaded MF-GA / IL-coated MPN microcapsule preparation is obtained by packaging the two drugs including mangiferin and glycyrrhizic acid with the ionic liquid as the core and the metal phenol network as the shell, the tissue permeability of the drugs is improved, a certain slow release effect is achieved, and the effect of treating chronic pharyngitis is achieved. The bioavailability of mangiferin and glycyrrhizic acid is improved, and the anti-inflammatory activity effect is better achieved.

The invention discloses a mineralization repair type oral cavity and throat nursing material for middle-aged and elderly people and a preparation method thereof. The nursing material consists of a core mineralization precursor, a function relieving component and an auxiliary synergistic component, wherein the core mineralization precursor is a biocompatible mineralization matrix of modified hydroxyapatite loaded carbon nitride quantum dots, and is used for realizing mucous membrane mineralization repair; the functional soothing component is a mixture of dihydromyricetin, a licorice extract and a menthol-beta-cyclodextrin inclusion compound, and has mild soothing and anti-inflammatory effects; the auxiliary synergistic component is a mixture of bovine serum albumin and a gamma-polyglutamic acid-g-methoxypolyethylene glycol derivative, and a mineralized precursor is stabilized and mucous membrane adhesion is enhanced by constructing a protein nanocage structure. By optimizing the process, the production efficiency and stability are improved, the biological safety is enhanced, the nursing requirements of middle-aged and elderly oral cavity and throat sensitive mucous membranes are better met, and the oral cavity and throat sensitive mucous membrane repairing gel is suitable for oral cavity mucous membrane sensitive repairing and chronic pharyngitis auxiliary nursing.

The invention relates to a recombinant human interferon alpha1b solution as well as a preparation method and application thereof, and belongs to the technical field of pharmaceutical preparations. The technical problems that in the prior art, the production cost is increased and the risk of blood virus infection exists due to the fact that the recombinant human alpha interferon spray is prepared from human albumin are solved. The recombinant human interferon alpha 1b solution comprises recombinant human interferon alpha 1b, gelatin, a pH regulator, a surfactant, a bacteriostatic agent and water, and further comprises one or more of an antioxidant, a thickening agent and an osmotic pressure regulator. The recombinant human interferon alpha1b solution is good in product quality and good in stability, can be stored for at least 24 months at the temperature of 2-8 DEG C under the dark condition, and can be stably stored for 3 months under the common indoor condition; the compound can be applied to preparation of medicines for treating or preventing diseases (herpes simplex, herpangina of children, hand-foot-and-mouth disease and respiratory diseases) caused by virus infection.

Composition for use for the treatment and / or prevention of infections or lesions of the (oral) mucosa, in particular originating from at least one selected the group consisting of: perleche; scarlet fever; pharyngitis; acute necrotising ulcerative mucositis; impetigo contagiosa; chelitis glandularis apostem atosa; gingivostomatitis herpetica; herpes simplex; herpes stabistis recidivans; herpes zoster; hand-foot-mouth; human papilloma virus; HIV; oral candidiasis; oral lichen planus; lichen ruber planus; leukoplakia, erythroplakia; methicillin-resistant staphylococcus aureus; gingivitis / periodontitis; mucositis / peri- implantitis; alveolar osteolytis; wherein the composition comprises or consists of the following components: (a) polyhexanide (PHMB); (b) an organic or inorganic buffer different from a); (c) further additives; (d) optionally water.

This invention provides a traditional Chinese medicine compound for treating chronic pharyngitis, belonging to the field of biomedical technology. The invention comprises a self-formulated traditional Chinese medicine compound consisting of *Pearl Umbrella*, *Trichosanthes kirilowii*, *Sapindus mukorossi*, *Lycoperdon perlatum*, *Panax japonicus*, *Gnaphalium affine*, *Aster tataricus*, and prepared licorice root for the treatment of chronic pharyngitis. Addressing the complex pathogenesis of chronic pharyngitis, characterized by a mixture of deficiency and excess, phlegm and blood stasis, and yin deficiency, the ingredients in the compound are rationally combined and work synergistically to achieve the effects of promoting blood circulation without depleting yin, clearing heat without harming yang, resolving phlegm without hindering the spleen, nourishing yin without being cloying, combining tonification and purgation, using both warming and cooling methods, and treating both the root cause and the symptoms. This compound is suitable for the treatment and management of chronic pharyngitis.

The invention discloses a traditional Chinese medicine composition for treating chronic pharyngitis and application of the traditional Chinese medicine composition, and belongs to the technical field of traditional Chinese medicine, the traditional Chinese medicine composition comprises the following components in parts by weight: 10-20 parts of radix glehniae, 10-20 parts of radix ophiopogonis, 10-20 parts of radix scrophulariae, 10-20 parts of radix salviae miltiorrhizae, 15-25 parts of radix rehmanniae, 15-25 parts of radix paeoniae rubra, 20-30 parts of rhizoma cimicifugae, 1-8 parts of liquorice and 10-20 parts of semen sesami nigrum. The traditional Chinese medicine composition blocks the case development of chronic pharyngitis from the two aspects of tonifying deficiency and removing stasis, plays a good role in treating chronic pharyngitis, and effectively solves the problems existing in the prior art.

Provided herein are formulations for use in enteral tube feeding, that contain one or more whole food-based ingredients, mineral nutrients, small molecules, and / or large molecules, the combination of which is effective to bind bile acids when administered to a subject in need thereof. The combination of crafted ingredients for tube feeding reduce symptoms of gastroesophageal reflux, vomiting, abdominal pain, irregular stooling (diarrhea or constipation) and to reduce organ damage including pneumonia, pharyngitis, aspiration, esophagitis, gastritis and enteritis.

Provided herein are pharmaceutical compositions, therapeutic combinations, devices and methods for treating, ameliorating, reversing, causing the remission of, and / or preventing (acting as a prophylaxis, or preventing the initiation of) an inflammatory bowel disorder (IBD) or inflammatory bowel disease (IBD), Ulcerative Colitis; Crohn's disease; J-pouch; fistulising Crohn's disease; a Colitis which can be microscopic, lymphocytic or collagenous; an eosinophilic colitis; indeterminate colitis; idiopathic colitis; diverticulosis and diverticulitis; relapsing diverticulitis; constipation associated inflammatory bowel disease and / or small intestinal bacterial overgrowth; Irritable Bowel Syndrome (IBS) with or without diarrhoea, constipation or pain predominant IBS; periodontitis; rheumatoid arthritis; respiratory infections, appendicitis, vascular disorders such as thrombophlebitis; bacteremia; osteomyelitis; septic shock; Alzheimer's disease; Lemierre syndrome (postanginal sepsis); colonic polyps or adenomas (optionally hyperplastic, adenomatous or serrated adenomas) or preventing the growth of colonic polyps or adenomas, bowl cancer, or metastases (optionally preventing the initiation or promotion of bowl cancer or metastasis); pharyngitis; otitis; sinusitis; and any disease, symptom or condition caused or exacerbated by a Fusobacteria (optionally, a F. nucleatum or F. varium) infection. In alternative embodiments, pharmaceutical compositions comprise rifaximin alone or in combination with other antibiotics or drugs.

The invention discloses an aerosol inhalant containing cannabidiol and application of the aerosol inhalant. The aerosol inhalant is prepared from the following components: 3.0 to 5.0 g of cannabidiol, 2.2 to 2.6 g of honeysuckle flower extract, 1.0 to 1.5 g of bamboo leaf extract, a proper amount of water for injection and 9.0 to 15.0 g of glycerol, and the volume of the water for injection is fixed to 1000ml. The aerosol inhalant can be used for preventing and treating sphagitis.

The invention provides a tobacco additive composition for relieving respiratory tract discomfort symptoms. The tobacco additive composition comprises daidzein and naringenin. The tobacco additive disclosed by the invention has unique characteristics. When the tobacco is ignited, the daidzein and the naringenin are not changed by combustion, but are directly converted into gaseous states, and are inhaled into the respiratory tract of a human body along with smoke generated by combustion of the tobacco. The characteristic specially exerts positive effects on chronic pharyngitis and pharyngolaryngitis, not only can relieve diseases and prevent diseases, but also can assist in treatment, is free of any complications after being used for a long time, and provides a solid guarantee for health and safety of a user. In the aspect of use experience, the additive enables tobacco products to be better in taste, and the additive is easily accepted by vast smokers.

The present invention discloses an anti-inflammatory and antibacterial composition, and a preparation method and application thereof. The composition is obtained by compounding a turmeric plant extract and a Chinese herbal medicine extract, wherein the turmeric plant extract is a volatile oil extract of the turmeric plant; the Chinese herbal medicine extract contains houttuynia cordata extract, chrysanthemum extract, bupleurum extract, yew lily extract, andrographis paniculata extract, and capillaris extract; the properly matched composition has a significant synergistic effect and can enhance its anti-inflammatory and antibacterial effects. At the same time, the promotion of transdermal absorption of the composition was studied, and it was found that the piperine compounding scheme can significantly improve the transdermal absorption effect and improve the bioavailability of the composition. The anti-inflammatory and antibacterial composition of the present invention has the effects of clearing away heat and detoxifying, reducing swelling and draining pus, stopping bleeding and relieving pain, and anti-inflammatory and sterilizing. At the same time, it has the advantages of a short treatment course, high efficacy, no toxic side effects, no recurrence of the disease, and is not easy to develop drug resistance. It can be used to treat oral inflammation and pharyngitis.

The present invention addresses the problem of providing a novel technique for suppressing pharyngitis and restoring water swallowing reflex by using loxoprofen and / or a salt thereof. According to the present invention, provided is a pharmaceutical composition having a pharyngitis-inhibiting effect and containing at least one substance selected from the group consisting of loxoprofen, salts thereof, and hydrates thereof.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to traditional Chinese medicine granules for relieving sore-throat and clearing away lung-heat and a preparation method thereof. The granule is prepared from the following raw materials: honeysuckle flower, dried orange peel, Chinese olive, balloonflower root and licorice root, adopts a volatile oil extraction and water decoction synergistic enrichment technology, and realizes synergistic retention of volatile and water-soluble components through the steps of volatile oil independent extraction, low-temperature preservation, spray addition, low-temperature vacuum concentration and the like. The finished product is uniform in particle size, convenient to take, high in stability and suitable for chronic pharyngitis patients and people using sound for a long time. The traditional Chinese medicine composition solves the problems of active ingredient loss, poor stability and inconvenience in taking of traditional Chinese medicines, and has remarkable clinical application value.

The utility model belongs to the technical field of medical instruments, and particularly relates to a portable mouth and nose atomizer. The portable mouth-nose atomizer comprises an atomizer main body, a heating mechanism and a control mechanism, the atomizer body comprises a main machine box, a respirator arranged at the front end of the atomizer body and a liquid medicine box arranged on the main machine box. The main machine box comprises a mounting groove extending inwards from the top of the main machine box and an atomizing assembly arranged in the main machine box and communicated with the respirator. The heating mechanism is used for heating the liquid medicine box and comprises a heating sheet which is arranged at the bottom of the mounting groove and is opposite to the liquid storage chamber; the control mechanism is used for controlling the heating mechanism and the atomization assembly. Through cooperation of the atomizer body, the heating mechanism arranged on the main machine box and the control mechanism arranged on the main machine box, liquid medicine in the liquid medicine box is heated, so that the temperature of liquid medicine mist is increased, the temperature of the liquid medicine mist inhaled by a patient is appropriate, stimulation of low temperature to people can be effectively prevented, and the comfort of the patient is improved. The traditional Chinese medicine has a good treatment effect on patients suffering from rhinitis and pharyngitis.

The invention discloses a method for detecting a Wantongkang in-blood core bioactive component group and verification, serum, urine and excrement are collected as an experimental group after a preset time, and serum, urine and excrement of animals not given with Wantongkang are used as a control group; and detecting the experimental group and the control group by adopting liquid chromatography-mass spectrometry. The invention systematically analyzes the original components and metabolites of Wantongkang in blood plasma, urine and excrement of rats. 38 primordial components are detected in plasma, 48 urine and 89 excrement. The terpenoids may form a core pharmacodynamic material basis of WTYK for treating pharyngitis. A metabolic conversion path of picria fel-terrae glycoside IA, rosmarinic acid, isofraxidin, caffeic acid and apigenin-7-O-glucuronide is constructed through metabolic conversion analysis, and active metabolites of picria fel-terrae glycoside IA, rosmarinic acid, isofraxidin, caffeic acid and The network pharmacological research based on the in-blood component reveals that the WTYK plays a therapeutic role in treating the pharyngitis mainly by regulating key signal channels such as PI3K-Akt, MAPK, TNF, JAK-STAT and NF-kB, wherein the NF-kB signal channel is closely related to the occurrence and development of the pharyngitis.

The invention provides a tobacco additive composition for preventing and treating sphagitis. The tobacco additive composition comprises isorhamnetin and naringenin. The tobacco additive has unique properties, when tobacco is ignited, isorhamnetin and naringenin are not changed through a combustion mode but are converted into a gaseous state, and the isorhamnetin and the naringenin enter the respiratory tract of the human body along with gas generated by tobacco combustion. Due to the characteristic, the traditional Chinese medicine composition can play a positive role in chronic pharyngitis and pharyngolaryngitis, effectively relieve symptoms, prevent diseases and assist the treatment process, does not cause any complications after being used for a long time, and greatly guarantees the health and safety of a user. From the perspective of use experience, the tobacco product is endowed with good taste by the additive, and the additive can be appreciated and accepted by the majority of smokers.

The invention belongs to the field of extraction technology of Ilex fringeii, discloses a kind of preparation method and use of Ilex fringeii total alkaloids, the method is:Take Ilex fringeii dried bulb and crush, sieve, 60 80% ethanol solution reflux extraction, filter, concentrate to dry paste;Use 1 3% HCl solution to dissolve, filter, filtrate is repeated on cation exchange resin;Sequentially eluted with deionized water and 50 70% NaCl ethanol solution, collect ethanol eluent and concentrate to dry paste;Add absolute ethanol, adjust pH to weak alkaline rear hot reflux extraction, filter the extract and be concentrated under reduced pressure to no alcohol taste;Add 1 3% HCl to dissolve completely, adjust pH to 8 9, repeatedly load over macroporous resin;Sequentially eluted with deionized water, ethanol solution of different volume concentrations;Collect target eluent decompression concentration, dry and obtain Ilex fringeii total alkaloid extract.Ilex fringeii total alkaloids of the present invention can be used for developing medicines for the treatment of chronic respiratory diseases, including: chronic obstructive pneumonia, chronic pharyngitis, pulmonary fibrosis.

The invention belongs to a traditional Chinese medicine formula for treating pharyngitis. The traditional Chinese medicine composition is prepared from a plurality of Chinese herbal medicines in proportion, and is suitable for treating acute and chronic pharyngitis such as swollen sore throat, hoarseness, foreign body sensation in throat, dysphagia and the like caused by wind-heat toxin. The formula is definite in curative effect, has the total effective rate of 98% or above, does not have toxic or side effects, and particularly has a unique curative effect on hoarseness. The formula belongs to a special-effect good formula.

This invention discloses a traditional Chinese medicine composition for the prevention and treatment of throat and oral diseases, and its preparation method. The composition comprises poultry egg yolk oil, honey, platycodon root, dandelion, licorice, monk fruit, menthol, and maltose in specific weight proportions. Its preparation includes steps such as frying poultry egg yolk oil, preparing water extracts of platycodon root and dandelion, and mixing with maltose to form a final product. The composition of this invention uses only food-grade medicinal materials, ensuring safety and reliability. When formulated into topical dosage forms such as lozenges, it provides long-lasting effects on the affected area, offering multiple benefits including analgesia, anti-inflammation, mucosal repair, and cough suppression. It effectively solves the problems of significant side effects and limited duration of local application in existing oral medications. This product has a pleasant taste and high patient compliance, making it suitable for the prevention and treatment of throat and oral diseases such as pharyngitis, tonsillitis, oral ulcers, gingivitis, and sore throat.

The invention provides a traditional Chinese medicine composition for treating chronic pharyngitis, a traditional Chinese medicine preparation and a preparation method thereof, and the traditional Chinese medicine composition comprises the following components in parts by weight: 2-80 parts of physalis alkekengi, 1-70 parts of sugarcane, 1-60 parts of laver, 1-50 parts of lily, 1-50 parts of American ginseng, 1-50 parts of pseudo-ginseng, 1-40 parts of pericarpium citri reticulatae, 1-40 parts of semen coicis and 1-40 parts of lotus seed. The invention further provides a traditional Chinese medicine preparation for treating chronic pharyngitis and a preparation method thereof. The traditional Chinese medicine composition has a remarkable curative effect on chronic pharyngitis, the raw materials of the traditional Chinese medicine composition are all medicinal and edible varieties, are high in safety, free of toxicity and side effects, wide in raw material source, easy to obtain and suitable for being taken for a long time, and the preparation method of the traditional Chinese medicine composition is easy and convenient to operate, can achieve large-scale industrial production and is beneficial to industrial application of the composition.

The invention discloses a special health-care beverage for treating sphagitis. The formula of the special health-care beverage comprises smoked plum, seville orange flower, endothelium corneum gigeriae galli, kelp, momordica grosvenori, platycodon grandiflorum and water. The beverage is carefully selected from natural plant raw materials, has multiple effects of clearing away heat and toxic materials, relieving sore-throat, diminishing swelling, relieving cough and reducing sputum, has no toxic or side effect, and is safe and reliable. The preparation process is simple, convenient, easy to operate and suitable for large-scale production and daily drinking.

The invention provides a quality detection method of an anti-pharyngitis traditional Chinese medicine compound extract, which adopts high performance liquid chromatography for qualitative and quantitative analysis of iridin and arctiin, and adopts ultraviolet-visible spectrophotometry for quantitative analysis of total flavonoids. Furthermore, comprehensive evaluation is carried out by taking the contents of iridin, arctiin and total flavonoids as well as the yield of the extract as indexes, the extraction time and the solvent amount which have great influence on the water extraction effect are investigated, and the extraction process of the anti-pharyngitis traditional Chinese medicine compound extract is optimized; the high performance liquid chromatography and the ultraviolet-visible spectrophotometric method are good in linear relation, high in precision, good in repeatability and accurate in determination result, and qualitative and quantitative analysis are combined to lay a foundation for establishing the quality standard of the anti-pharyngitis traditional Chinese medicine compound extract.

The invention discloses a micro-magnetic far-infrared nasal lung therapeutic apparatus, and relates to the technical field of medical supplies, the micro-magnetic far-infrared nasal lung therapeutic apparatus comprises an interlayer sponge layer, a graphene heating sheet, a knitted pure cotton layer, a soft magnetic sheet, a sandwich screen cloth layer and a fixing device, the fixing device is arranged on the back of the interlayer sponge layer, the graphene heating sheet is attached to the interlayer sponge layer, and the soft magnetic sheet is attached to the knitted pure cotton layer. The knitted pure cotton layer is attached to the graphene heating sheet, the soft magnetic sheet is attached to the knitted pure cotton layer, and the sandwich screen cloth layer is attached to the soft magnetic sheet. According to the traditional Chinese medicine, a series of symptoms such as breath promotion, asthma, cough, pharyngalgia, pharynx itching, rhinocnesmus, nasal obstruction, running nose and sneezing caused by heavy lung dampness can be removed through a physical method; the original biological magnetic field of the human body is conditioned and repaired through micro-magnetism to strengthen the exterior and protect the body, so that various diseases such as acute rhinitis, allergic rhinitis, chronic rhinitis, allergic pharyngitis and asthma of the nose and the lung and various acute and chronic infectious diseases of the lung are effectively treated.

This invention provides a traditional Chinese medicine composition, characterized in that the composition comprises: 0.5-1 parts by weight of honey-processed ephedra, 0.5-1.5 parts by weight of bitter almond, 0.5-1 parts by weight of perilla seed, 1.5-3 parts by weight of mulberry bark, 1.5-2 parts by weight of scutellaria, 0.5-1.5 parts by weight of cicada slough, 0.5-1.5 parts by weight of silkworm, 1.5-3 parts by weight of earthworm, 0.5-1.5 parts by weight of angelica root, 0.5-1.5 parts by weight of belamcanda rhizome, 1.5-3 parts by weight of coltsfoot flower, 0.5-1.5 parts by weight of prepared pinellia tuber, and 0.5-1 parts by weight of licorice root. This invention provides a traditional Chinese medicine composition that works synergistically to relieve lung congestion and asthma, suppress cough, clear heat, and resolve phlegm. Modern pharmacological experiments have shown that this composition can be used to treat bronchial asthma or its chronic persistent phase, bronchitis with cough, and pharyngitis.

The invention relates to a quality detection method of a traditional Chinese medicine composition for acute and chronic pharyngitis. The quality detection method comprises the steps of identifying components of the traditional Chinese medicine composition and determining the content of the traditional Chinese medicine composition, in the aspect of component identification, an ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry is adopted, and the method is high in resolution, high in quality precision and high in sensitivity, and can be used for rapidly and accurately identifying eight characteristic components from monarch drug scutellaria baicalensis, ministerial drugs honeysuckle and mint, adjuvant drug radix scrophulariae and conductant drug fructus chebulae immaturus at one time; the reliable technical support is provided for the definition of the material basis of the preparation; in the aspect of content determination, a high performance liquid chromatography method for simultaneously determining the components of baicalin, chlorogenic acid and gallic acid is established. Through verification, the method has the advantages of good precision, repeatability and stability, ideal sample recovery rate, simple and rapid operation and accurate and reliable result, is suitable for production process monitoring and finished product batch release inspection of the preparation, and can be used for quality control and technical reference of the traditional Chinese medicine granules.

The invention discloses a preparation method and application of Pudilan direct granules, and belongs to the technical field of traditional Chinese medicine preparations. The directly-taken granules are prepared by extracting and concentrating four Chinese herbal medicines including dandelion, isatis root, bunge corydalis herb and scutellaria baicalensis to obtain extracts according to a specific process, the directly-taken granules suitable for being taken are prepared, the bad taste of the medicine is effectively covered, and the problem of the taste of the medicine is solved. The traditional Chinese medicine composition has the effects of clearing away heat and toxic materials, resisting inflammation, diminishing swelling and the like, and is used for treating diseases such as parotitis, pharyngitis, amygdalitis or furuncle. The pudilan directly-taken granules disclosed by the invention are suitable for children to take.

The invention relates to the technical field of medicine preparation, in particular to burka granules, a preparation process and application of the burka granules in preparation of antipyretic, anti-inflammatory and cough-relieving medicines. According to the invention, the medicine for treating and preventing the heat type common cold is obtained by adopting the burka particles for the first time, and has the characteristics of rapid efficacy, long shelf life of the efficacy, stable efficacy and convenience in taking; the love granules provided by the invention have the curative effects of clearing heat, diminishing inflammation, relieving cough and the like in animal experiments. The traditional Chinese medicine composition has the effects of conditioning abnormal bile fluid, abating fever and dredging obstruction in clinical application, is used for sweating of fever infectious diseases, cold, cough, pharyngitis and the like, and has a good application prospect in medicines for preventing and / or treating influenza and acute upper respiratory infection. Meanwhile, the preparation method is safe, simple and convenient, and compared with a traditional preparation, the medicine compliance can be obviously improved. The prepared burka granules disclosed by the invention are convenient to store and transport.

Provided is a formulation useful for treating sore throat, throaty cough, xerostomia, pharyngitis, laryngitis, postoperative pain, dysphagia, laryngeal granuloma, vocal optimization, laryngopharyngeal reflux or dysbiosis, wherein the formulation comprises: an aqueous solution comprising one or more active ingredients selected from the group consisting of marshmallow root, slippery elm extract, aloe vera extract, manuka honey, honey, holy basil, menthol, spearmint, capsaicin, propolis, curcumin, xylitol, turmeric, probiotics, and calendula, the aqueous solution being present as aerosolized particles in a range of 10 to 35 microns.