19 results about "Chronic cough" patented technology

The application belongs to the technical field of traditional Chinese medicines, and particularly relates to a preparation method of a traditional Chinese medicine composition for intractable chronic cough and application thereof; and particularly discloses a traditional Chinese medicine composition for treating intractable chronic cough, which comprises, by weight fraction, 10-40 parts of Poria cocos, 3-25 parts of fried licorice, 3-20 parts of Schisandra chinensis, 1-20 parts of dried ginger, 1-12 parts of Asarum, 3-20 parts of prepared pinellia, 3-20 parts of bitter apricot kernel, 5-40 parts of white mulberry bark, 3-25 parts of bupleurum, 3-25 parts of wind-protecting plant, 5-40 parts of north-sand peony and 1-5 pieces of centipede. The application is a pure traditional Chinese medicine prescription, has high safety and good efficacy, and can quickly relieve symptoms of intractable chronic cough patients, and is suitable for clinical popularization and application due to wide drug source.

Systems, methods, and computer programs disclosed herein relate to training and using a machine learning model for classifying individuals suffering from chronic cough at least partially based on information about cough events of the patient.

The invention relates to the use of camlipixant in the treatment of cough, in particular chronic cough, and drug-drug interactions when administered with a CYP3A4 inducer and / or CYP2C8 inducer.

Provided herein are compounds, including ifenprodil, and pharmaceutical compositions for use in treating refractory chronic cough. The compounds and pharmaceutical compositions may also be suitable for treating refractory chronic cough in subjects also diagnosed with idiopathic pulmonary fibrosis.

The invention relates to the technical field of data processing, in particular to a system and a method for auxiliary analysis of hormone-sensitive chronic cough, and the method comprises the following steps: collecting target indexes of a patient, including allergic disease history, sour regurgitation heartburn symptom, hematophilic granulocyte count, CRP, IgE, FEV1 / FVC and FeNO; preprocessing the target index to obtain a preprocessed index; and generating a risk score corresponding to the hormone-sensitive chronic cough according to the pretreatment index. In order to solve the problems that in the prior art, hormone-sensitive cough diagnosis indexes need to depend on a complex detection instrument to be collected, and implementation is difficult, on the basis of regression analysis, the indexes of auxiliary analysis are determined to be clinical data which can be obtained easily based on clinical symptoms, blood routine indexes, lung function examination and the like of a patient, and the hormone-sensitive cough diagnosis indexes are obtained. And a related auxiliary analysis system is established, so that complex instruments required in the traditional medical examination process are omitted, and the medical examination process can be quickly completed in any level of medical institutions.

The invention relates to a salt derivative of (R)-6-(5-fluoropyridin-2-yl)-8-methoxy-N-(1-(5-methyl-1, 2, 4-oxadiazol-3-yl) ethyl) quinazoline-4-amine, in particular to a salt derivative of (R)-6-(5-fluoropyridin-2-yl)-8-methoxy-N-(1-(5-methyl-1, 2, 4-oxadiazol-3-yl) ethyl) quinazoline-4-amine, and a salt derivative of (R)-6-(5-fluoropyridin-2-yl)-8-methoxy-N-(1-(5-methyl-1, 2, 4-oxadiazol-3-yl) ethyl) quinazoline-4-amine. The present invention relates to mesylate and ethanesulfonate salts of 2, 4-oxadiazol-3-yl) ethyl) quinazolin-4-amine, pharmaceutical compositions containing such salts, and therapeutic uses thereof. The salts of the invention are useful in the treatment of diseases or conditions associated with respiratory diseases, in particular chronic cough.

The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for treating refractory chronic cough and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 6-12 parts of ephedra, 6-12 parts of semen armeniacae amarae, 6-12 parts of scutellaria baicalensis, 6-12 parts of gardenia jasminoides, 4-8 parts of platycodon grandiflorum, 6-12 parts of radix ophiopogonis, 6-12 parts of thunberg fritillary bulb, 6-12 parts of exocarpium citri rubrum, 6-12 parts of poria cocos, 4-8 parts of white mulberry root-bark, 4-8 parts of rhizoma anemarrhenae, 4-8 parts of semen trichosanthis and 6-12 parts of honey-fried licorice root. The compatibility of the traditional Chinese medicine composition accords with the theory of monarch, minister, assistant and guide in traditional Chinese medicine, the compatibility is ordered, and the whole formula has the effects of dispelling cold, clearing heat, nourishing yin, relieving cough and reducing phlegm. Clinical effects show that after the traditional Chinese medicine composition is used for treating the refractory chronic cough for two weeks, the total effective rate of treatment reaches up to 97.73%, and the treatment effect is remarkable.

The invention provides a cough-relieving medicine for treating chronic cough after respiratory virus infection and a preparation method thereof, and relates to the technical field of traditional Chinese medicines. The cough-relieving medicine disclosed by the invention is prepared from fructus mume, radix platycodonis, herba taraxaci, rhizoma dioscoreae, honeysuckle flower, fructus jujubae and fructus momordicae. According to the invention, dandelion and honeysuckle are used as monarch drugs, momordica grosvenori and platycodon grandiflorum are used as ministerial drugs, Chinese yam and jujube are used as adjuvant drugs, and dark plum is used as a conductant drug. By adjusting the composition of the raw materials, the raw materials play a synergistic role, and the prepared cough relieving medicine has the effects of tonifying lung deficiency, eliminating cold-dampness, eliminating dampness and heat, freeing lung qi and the like.

1. Name of the product in this design: Fog reservoir (for both mouth and nose). 2. Intended use of this design: an inhalation device for the simultaneous treatment of rhinitis, asthma, adenoid hypertrophy, allergic rhinitis-asthma syndrome, chronic cough, and COPD. 3. The key design feature of this product is its shape. 4. The picture or photo that best illustrates the key design points: Design 1 Combined State Diagram 1. 5. Design 1 is designated as the basic design. 6. Other situations requiring explanation: In the 3D diagram of component 1, part A is made of transparent material.

The application belongs to the technical field of Chinese patent medicines, and provides a use of Guiling tablets in the preparation of a medicine for treating stress urinary incontinence or bladder cough. On the basis of the known efficacy of Guiling tablets, a commercially available Chinese patent medicine, for treating kidney deficiency causing asthma and lung deficiency causing chronic cough, the application uses the kidney tonifying and qi consolidating effect of Guiling tablets to treat stress urinary incontinence or bladder cough, and very significant effects are observed on the incontinence of urine caused by excessive cough and asthma due to kidney deficiency in the middle-aged and the elderly, especially in middle-aged and elderly women.

A digital therapeutic method for delivering personalized Behavioral Cough Suppression Therapy through an electronic device, such as a smartphone, operates by collecting both objective data (such as cough sounds detected by the device's microphone and analyzed by a processor) and subjective data (self-reported by the patient through the app). By combining these two data streams, the device automatically generates personalized recommendations for cough suppression strategies. The method includes detecting patterns in cough events, such as trends over time, bouts of coughing, or periods of reduced coughing, and adjusting recommendations dynamically. The system also tracks adherence to therapy, guides patients through suppression training sessions, and generates progress reports. It can elicit potential cough triggers and deliver specific advice for managing them. Importantly, the recommendation engine can use machine learning to refine its suggestions based on ongoing data, enabling increasingly tailored and effective support.

The present invention relates to salt derivatives of (R)-6-(5-fluoropyridine-2-yl)-8-methoxy-N-(1-(5-methyl-1,2,4-oxadiazole-3-yl)ethyl)quinazoline-4-amine, and more particularly to mesylates and esylates of (R)-6-(5-fluoropyridine-2-yl)-8-methoxy-N-(1-(5-methyl-1,2,4-oxadiazole-3-yl)ethyl)quinazoline-4-amine, pharmaceutical compositions containing them, and their therapeutic uses. The salts of the present invention may be useful in the treatment of respiratory diseases, particularly diseases or conditions associated with chronic cough.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating plateau chronic cough, which is prepared from the following raw materials in parts by weight: 2-30 parts of thunberg fritillary bulb, 2-30 parts of burdock root, 1-15 parts of radix asparagi, 1-15 parts of bamboo shavings, 1-15 parts of honey white mulberry root-bark, 1-15 parts of fructus chebulae, 1-10 parts of pericarpium citri reticulatae, 1-15 parts of herba houttuyniae, 1-15 parts of radix glehniae, 2-30 parts of radix astragali and 2-10 parts of fructus momordicae.

The invention relates to the use of camlipixant in the treatment of cough, in particular chronic cough, and drug-drug interactions when administered with a CYP2C8 inhibitor.

The invention discloses a traditional Chinese medicine composition for treating chronic cough caused by phlegm-dampness obstructing lung and wind-disturbing reversed-qi flow as well as a preparation method and application of the traditional Chinese medicine composition, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10 to 18 parts of radix bupleuri, 7 to 14 parts of radix scutellariae, 10 to 18 parts of rhizoma pinelliae, 10 to 14 parts of cortex magnoliae officinalis, 8 to 12 parts of semen armeniacae amarae, 7 to 12 parts of lumbricus, 10 to 15 parts of poria cocos, 6 to 12 parts of fructus perillae, 6 to 12 parts of radix platycodonis and 8 to 12 parts of radix angelicae sinensis. The radix bupleuri and the pinellia ternate are used as monarch drugs for treating core pathogenesis, the ministerial drugs are used for assisting and synergism, the adjuvant drugs are used for comprehensively complementing the pathogenesis and performing targeted conditioning, so that the drugs are used for guiding channels and regulating the middle warmer, strengthening the body resistance and harmonizing and progressively increasing layer by layer, the symptoms such as cough, asthma and excessive phlegm are quickly relieved, and the effects of reducing phlegm, clearing damp, regulating qi activity, fixing and protecting lung and spleen and completely eradicating relapse are achieved. The traditional Chinese medicine composition accords with the principle that the symptoms are treated when urgent treatment is carried out and the root is treated when slow treatment is carried out, and a unique treatment scheme is formed.

The invention discloses a preparation method of a traditional Chinese medicine ointment for treating cough. The preparation method comprises the following steps: step 1, preparing materials; step 2, crushing; step 3, mixing; step 4, extracting and concentrating; step 5, forming; the prescription is derived from a classic famous prescription, and the whole prescription has the effects of replenishing qi to invigorate the spleen, drying dampness, reducing phlegm, ventilating the lung and relieving cough. A chronic cough patient with a long course of disease is often deficient in both qi and yin. Ginseng with mild medicine property has strong energy tonifying capacity, but can help dampness to generate heat or warm dryness hurts lung yin, and is not the best choice for phlegm-dampness symptoms. The radix pseudostellariae has the effects of tonifying qi and yin, is mild in nature, can promote salivation and moisten the lung while tonifying qi of the spleen and the lung, and conforms to the chronic cough pathogenesis of spleen deficiency and excessive dampness and slight lung fluid damage.

The present invention relates to methods for treating patients with refractory chronic cough (RCC) with nalbuphine compositions, wherein the method provides a therapeutic effect in a patient.