4 results about "Nerve degeneration" patented technology

The invention discloses application of glutaric acid or medicinal salt thereof in medicine, a medicine composition and a medicine preparation, and belongs to the field of medicine application. According to the application of the glutaric acid or the medicinal salt thereof in preparing the medicine for inhibiting neurodegeneration, promoting lysosomal activity and treating the Alzheimer's disease, a new potential treatment medicine is provided for treatment of the Alzheimer's disease, and a more effective scheme for treating the Alzheimer's disease is provided.

The present invention provides a method for preparing mesenchymal stem cell exosomes, which is convenient to obtain materials and has low cost. It can quickly and efficiently prepare a large amount of high-purity mesenchymal stem cell-derived exosomes, which can effectively reduce costs and increase yields compared to the prior art, and is suitable for large-scale application; the exosomes can be used to promote the growth and repair of nerve cells, and can induce neural progenitor cells to differentiate into various nerve cell forms such as neurons and peripheral nerves; drugs can enter the cerebrospinal fluid through the exosomes, alleviate brain nerve degeneration, can pass through the blood-brain barrier, and can be used as a natural carrier for drugs for treating central nervous system diseases; it can regulate the growth of epidermal cells, promote the secretion of inflammatory cytokines in the microenvironment, stimulate angiogenesis and collagen deposition at skin defects, and regulate the proliferation and differentiation of skin fibroblasts, thereby accelerating skin tissue regeneration and repair; it can effectively promote hair follicle regeneration, thereby achieving a hair growth effect.

The present invention provides an active substance of Lactic Acid Bacteria, a composition comprising thereof and its use for promoting longevity, especially for increasing Cisd2 gene expression, reducing mitochondrial damage and delaying aging conditions such as nerve degeneration and sarcopenia.

The present disclosure relates to peptide compositions and methods for treating an inflammatory condition such as ocular inflammation, retinal inflammation, dry eye, uveitis, allergic conjunctivitis, and inflammation resulting from nerve injury or nerve degeneration. The peptide compositions disclosed herein can also be used for treating pain such as neuropathic pain, ocular pain, chronic pain, pain resulting from chemotherapy or radiation, pain resulting from nerve injury or nerve degeneration, and pain resulting from an inflammatory condition, dysesthesia, or allodynia.