139results about How to "Prevent good" patented technology

An apatite-coated solid composition which contains a biodegradable polymer and an apatite-coated solid composition which contains a biodegradable polymer and a medicinal substance have properties of sustained release and of osteoconductive activity.

The invention describes the use of a PDE4 inhibitor in combination with BH4 or a BH4 derivative for the prevention and/or treatment of respiratory diseases.

A side light type spread illuminating apparatus comprises: a light conductive plate having a plurality of prisms formed on a light exit surface thereof, point light sources; and a prism sheet disposed on the light conductive plate, wherein the prisms have respective circular arc configurations with a common curvature in cross section taken along a line orthogonal to the direction the prisms extend, and are arrayed such that distances each defined between apexes of adjacent two of the prisms differ irregularly from one another within a range of 10 to 200 μm, and such that overall tangential angles at respective ends of the prisms vary irregularly within a range of 40 to 70 degrees, and wherein the respective ridges of the prisms are located on a common virtual plane, whereby the prism sheet are supported evenly by all of the prisms of the light conductive plate.

A stent device is provided. The stent device includes a stent body and one or more HDAC inhibitor depot(s) provided on or in the stent body, the depot(s) capable of controllably releasing HDAC inhibitor(s). Methods of using the stents in treating and/or preventing restenosis are provided. A delivery system including the stent device and a methods of using the delivery system in treating and/or preventing restenosis are also provided. Kits comprising stents are provided.

An optical film includes a filmy support that includes a polymer having all alicyclic structure; an ultraviolet absorbing layer; and a hardcoat layer, wherein the ultraviolet absorbing layer has a beam transmittance of 5% or less in a wavelength region of 200 to 340 nm and includes at least one ultraviolet absorbent selected from the group consisting of a metal oxide fine particle and a polymer particle.

A manufacturing method for a semiconductor device that has a first region for memory elements and a second region for elements other than memory elements on a substrate, includes forming a first interlayer dielectric film on the substrate. A first opening section, which is made to reach the substrate, is formed in the first interlayer dielectric film over the first region. A second opening section, which also reaches the substrate, is formed in the first interlayer dielectric film over the second region. A first plug electrode is formed in the first opening section and a second plug electrode is formed in the second opening section. A ferroelectric capacitor is formed on the first interlayer dielectric film and made to cover and contact the first plug electrode. A first wiring pattern covering and contacting the second plug electrode is formed on the first interlayer dielectric film. A second interlayer dielectric film, which covers the ferroelectric capacitor and the first wiring pattern, is formed on the first interlayer dielectric film. A third opening section is then made in the second interlayer dielectric film over the second region and reaching the first wiring pattern. A third plug electrode is formed in the third opening section.

A colored coating material for a color mirror that includes a film-forming component, a pigment, and a solvent, wherein the pigment, which comprises a calcined inorganic pigment comprising one or more elements or oxides of elements selected from the group consisting of Fe, Mn, Co, Ni, Al, Cr, Ti, Sb, Cu, Si, Zn, Li and P, and has a primary particle average particle size of no more than 0.1 μm, is used in a quantity within a range from 40 to 90% by mass relative to the combined weight of the film-forming component and the pigment.

The present invention is to provide a multiple-agents-binding compound comprising a compound having anti-HIV activity and having no affinity for cell surface protein bound together with a same or different kind of at least one compound having anti-HIV activity and having no affinity for cell surface protein, or a salt thereof, and a pharmaceutical composition for the prevention or treatment of infectious diseases of HIV or AIDS comprising said multiple-agents-binding compound.

An object of the present invention is to provide a water-in-oil type emulsion sunscreen cosmetic which can achieve excellent UV protection capability and have excellent effects in the prevention and inhibition stability of discoloration with the passage of time.

The water-in-oil type emulsion sunscreen cosmetic in the present invention is characterized by comprising 1 to 30% by mass (a) hydrophobized titanium oxide and/or zinc oxide, 0.1 to 10% by mass (b) phenylbenzimidazole sulfonate, 50% by mass or more (c) triethanolamine with respect to the component (b), 0.1 to 10% by mass (d) trimethylsiloxysilicate and further, if desired, 0.01 to 20% by mass (e) silicone surfactant.

A magnetic core has a structure in which Fe-based soft magnetic alloy particles are connected via a grain boundary. The Fe-based soft magnetic alloy particles contain Al, Cr and Si. An oxide layer containing at least Fe, Al, Cr and Si is formed at the grain boundary that connects the neighboring Fe-based soft magnetic alloy particles. The oxide layer contains an amount of Al larger than that in Fe-based soft magnetic alloy particles, and includes a first region in which the ratio of Al is higher than the ratio of each of Fe, Cr and Si to the sum of Fe, Cr, Al and Si, and a second region in which the ratio of Fe is higher than the ratio of each of Al, Cr and Si to the sum of Fe, Cr, Al and Si. The first region is on the Fe-based soft magnetic alloy particle side.

The present invention regards cancer-specific control sequences that direct expression of a polynucleotide encoding a therapeutic gene product for treatment of the cancer. Specifically, the invention encompasses breast cancer-specific and ovarian cancer-specific control sequences. Two breast cancer-specific sequences utilize specific regions of fatty acid synthase and claudin 4 promoters, particularly in combination with a two-step transcription amplification sequence and/or a post-transcriptional control sequence. Two ovarian cancer-specific sequences utilize specific regions of hTERT and survivin promoters, particularly in combination with a two-step transcription amplification sequence and/or a post-transcriptional control sequence. In more particular embodiments, these polynucleotides are administered in combination with liposomes.

Compositions are provided for the intranasal administration of granisetron or a pharmaceutically acceptable salt thereof. Preferred compositions are in the form of an aqueous solution. Optionally, the compositions comprise chitosan, a salt or derivative thereof or a salt of a derivative of chitosan. The compositions can be used for the treatment or prevention of nausea and/or vomiting.

The present invention provides water-in-oil type emulsion sunscreen cosmetics that achieve an excellent UV blocking effect, and have excellent effects in the prevention and inhibition of discoloration (discoloration to red). The water-in-oil emulsion sunscreen cosmetic according to the present invention is characterized by comprising: (a) octocrylene; (b) hydrophobized zinc oxide; (c) cationic surfactant; and (d) silica.

A material comprising at least one polymer and at least one sensitizer wherein the sensitizer is localised at a surface of the material wherein the sensitizer is an agent or compound able to provide improved anti-bacterial and/or anti-viral activity following exposure of the sensitizer to a particular wavelength or range of wavelengths of electromagnetic radiation.

The present invention relates to a cosmetic, dietary supplement, or pharmaceutical composition for oral ingestion or topical application to the skin comprising effective amounts of a tocopherol quinone, tocopherol quinol, plastoquinol, menaquinol, or phylloquinol compound, or any combination thereof as a method for preventing free radical oxidation or preventing or treating environmental skin damage including photoaging, trauma, discoloration, dryness, thickness, elasticity, or wrinkles.

The present invention regards cancer-specific control sequences that direct expression of a polynucleotide encoding a therapeutic gene product for treatment of the cancer. Specifically, the invention encompasses breast cancer-, prostate cancer-, and pancreatic cancer-specific control sequences. Two breast cancer-specific sequences utilize specific regions of topoisomerase IIα and transferrin receptor promoters, particularly in combination with an enhancer. The prostate cancer-specific and pancreatic cancer-specific control sequences utilize composites of tissue-specific control sequences, a two-step transcription amplification sequence, and a post-transcriptional control sequence. In more particular embodiments, these polynucleotides are administered in combination with liposomes.

The invention relates to the use of N-desulfated heparin for treating or preventing inflammation, which is based on the experimental results in animal acute abdominal inflammation model and animal bleed model. The N-desulfated heparin's anti-inflammation activity is better than or equal to that of the low molecular weight heparin, and has low activity of anti-coagulant. From a series of N-desulfated heparin of different N-sulfur-containing, a sample of the best anti-inflammation activity and the lowest anti-coagulant activity was selected. The invention solved the problem of bleeding in the use of heparin for treating of inflammation, and provided a new pathway to use heparin to prevent and treat inflammation.

The present invention provides an application of a periplaneta americana medicinal powder or a periplaneta americana extract in preparation for a medicine used for preventing and treating radiation-induced damages. The medicine is capable of preventing and treating the damages caused by radiation therapy for nasopharyngeal cancer, esophageal cancer, stomach cancer, lung cancer, liver cancer, breast cancer, waldeyer's lymphoma, and other cancers. Through test verification, the medicine of the present invention has an obvious prevention and treatment effect for damages caused by radiation therapy for patients with breast tumours and breast cancer after surgery.

The present invention relates to a gas barrier film including: an inorganic layer which contains oxygen atoms; and an organic-inorganic mixed layer which contains silica (SiO₂) formed on one surface of the inorganic layer. The inorganic layer has a first area that is adjacent to the organic-inorganic mixed layer; and a second area that is present below the first area in the thickness direction of the inorganic layer. The number of the oxygen (O) atoms in the first area is greater than the number of the oxygen atoms in the second area which is equal in volume to the first area. The gas barrier film is excellent in terms of gas barrier properties, flexibility, transparency, and crack prevention. In addition, the gas barrier film enables non-vacuum wet coating and is thus advantageous in shortening the manufacturing time.

A remotely controlled access system for a plurality of containers consisting of a plurality of intelligent access mechanisms for locking the containers, the intelligent access mechanisms being configured in a network to facilitate communication therebetween and with a central command node. Requests for access can be communicated from the central command node to the intelligent access mechanisms and event information can be communicated form the intelligent access mechanisms back to the central command node.

Disclosed are a metal curtain wall system of a monolayer structure and a construction method thereof. The metal curtain wall system comprises a plurality of composite material curtain wall units (1) that are produced in a numerical control manner and have complex models. The plurality of composite material curtain wall units (1) is spliced to form an inner-outer wall body model. Embedded members (2) are arranged in the composite material curtain wall units (1). Lead-out parts of the embedded members are oriented towards the inner and outer wall bodies and are fixed to inner and outer wall bodies. The composite material curtain wall units (1) in vertical adjacency are arrayed in a staggered manner. An elastic structural adhesive (3) is coated on surfaces of the composite material curtain wall units (1). Thin-type metal sheets (4) are covered on the elastic structural adhesive (3). The metal curtain wall system can be produced continuously in a numerical control manner in the production and manufacturing process. The precision of hyperbolic metal is improved in the environment-friendly and energy-saving manufacturing process. With a simple and mature process, the construction difficulty and the construction cost are reduced; resources or space is saved; and the complex digital building project is improved to the rank of the modern scientific and technical industry.

The present invention relates to novel urea derivatives and, more particularly, to novel urea derivatives with histone deacetylase (HDAC) inhibitory activity, isomers thereof, pharmaceutically acceptable salts thereof, their use for the preparation of a medicaments comprising the same, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing novel urea derivatives. The novel urea derivatives as selective histone deacetylase (HDAC) inhibitors are effective for the treatment of histone deacetylase-mediated diseases such as malignant tumors, inflammatory diseases, rheumatoid arthritis, neurodegeneration, etc.

A method of producing a volume hologram laminate which can regenerate a hologram image in an arbitrary wavelength by a simple process. The method uses a volume hologram forming substrate which includes: a substrate, a volume hologram layer formed on the substrate and containing a photopolymerizable material, a resin layer, formed on the substrate so as to contact to the volume hologram layer, containing a resin and a polymerizable compound. The producing method includes processes of: a hologram recording process to record a volume hologram to the volume hologram layer, a substance transit process of transiting the polymerizable compound to the volume hologram layer, and an after-treatment process of polymerizing the polymerizable compound.

An object of the present invention is to provide a water-in-oil type emulsion sunscreen cosmetic which can achieve excellent UV protection capability and have excellent effects in the prevention and inhibition stability of smell change with the passage of time.

The water-in-oil type emulsion sunscreen cosmetic in the present invention is characterized by comprising 0.2 to 10% by mass (a) octocrylene, 0.2 to 30% by mass (b) hydrophobized titanium dioxide and/or zinc oxide, 0.02 to 8% by mass (c) phenylbenzimidazole sulfonate, (d) a neutralizer for the above-mentioned component (c), and further, if desired, 0.01 to 20% by mass (e) silicone surfactant.